Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH2 DNAH7 RAB11FIP3

6.50e-05281574GO:0051959
GeneOntologyMolecularFunctionpotassium channel inhibitor activity

RASA1 CAV3 ENSA

7.51e-05111573GO:0019870
GeneOntologyMolecularFunctionpotassium channel regulator activity

ANK2 RASA1 CAV3 AKAP9 ENSA

8.49e-05571575GO:0015459
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH2 DNAH7 HTT

1.98e-04371574GO:0045505
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH2 DNAH7

3.57e-04181573GO:0008569
GeneOntologyMolecularFunctionmRNA cap binding complex binding

ZC3H18 SRRT

3.65e-0441572GO:0140262
GeneOntologyMolecularFunctioncytoskeletal protein binding

DCDC1 ANK2 ANK3 KLC2 TMOD4 RCSD1 ADGRV1 CAV3 TERF1 ITGB1 TTBK2 FGD4 ANKRD2 SNCB PLK1 TNS1 MX2 HTT TBCE HDGF

4.00e-04109915720GO:0008092
GeneOntologyMolecularFunctiontransmembrane transporter binding

ANK2 ANK3 RASA1 CAV3 AKAP9 KCNQ3 HTT

4.30e-041721577GO:0044325
GeneOntologyBiologicalProcesscilium assembly

SPAG1 ERICH3 KIAA0586 DNAH2 DYNC2I1 TTLL8 DNAH7 TBC1D8 TTBK2 CFAP221 IFT122 SGSM3 HTT CFAP46 RAB11FIP3

1.47e-0644415615GO:0060271
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

SPAG1 ERICH3 KIAA0586 DNAH2 DYNC2I1 TTLL8 ITGB1 DNAH7 TBC1D8 TTBK2 FGD4 CFAP221 IFT122 SGSM3 FGD3 HTT CFAP46 RAB11FIP3

3.33e-0667015618GO:0120031
GeneOntologyBiologicalProcesscilium organization

SPAG1 ERICH3 KIAA0586 DNAH2 DYNC2I1 TTLL8 DNAH7 TBC1D8 TTBK2 CFAP221 IFT122 SGSM3 HTT CFAP46 RAB11FIP3

3.46e-0647615615GO:0044782
GeneOntologyBiologicalProcesscell projection assembly

SPAG1 ERICH3 KIAA0586 DNAH2 DYNC2I1 TTLL8 ITGB1 DNAH7 TBC1D8 TTBK2 FGD4 CFAP221 IFT122 SGSM3 FGD3 HTT CFAP46 RAB11FIP3

4.53e-0668515618GO:0030031
GeneOntologyCellularComponentcostamere

ANK2 ANK3 AHNAK AHNAK2

2.02e-05221574GO:0043034
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH2 DNAH7

4.80e-05101573GO:0036156
GeneOntologyCellularComponentT-tubule

ANK2 ANK3 CAV3 AHNAK AHNAK2

3.23e-04791575GO:0030315
GeneOntologyCellularComponentcilium

ERICH3 DNAH10 KIAA0586 DNAH2 KLC2 DYNC2I1 ADGRV1 TTLL8 DNAH7 TTBK2 AKAP9 GUCY2F CFAP221 PRKAR1B TMEM218 IFT122 CFAP46

4.32e-0489815717GO:0005929
GeneOntologyCellularComponentcell-cell contact zone

ANK2 ANK3 CAV3 ITGB1 AHNAK

7.19e-04941575GO:0044291
GeneOntologyCellularComponentdynein complex

DNAH10 DNAH2 DYNC2I1 DNAH7

7.23e-04541574GO:0030286
GeneOntologyCellularComponentciliary base

DYNC2I1 TTBK2 PRKAR1B IFT122

8.30e-04561574GO:0097546
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAH2 DNAH7

8.47e-04251573GO:0005858
DomainSANT/Myb

BDP1 SMARCA5 CHD7 TERF1 MIDEAS MYSM1 SMARCA1 OSMR

1.20e-08521588IPR001005
DomainSANT

BDP1 SMARCA5 CHD7 TERF1 MIDEAS MYSM1 SMARCA1

2.00e-07501587SM00717
DomainMYB_LIKE

BDP1 SMARCA5 TERF1 MIDEAS MYSM1

1.63e-05381585PS50090
DomainSANT_dom

SMARCA5 MIDEAS MYSM1 SMARCA1

6.37e-05261584IPR017884
DomainSLIDE

SMARCA5 SMARCA1

7.11e-0521582IPR015195
DomainISWI_HAND-dom

SMARCA5 SMARCA1

7.11e-0521582IPR015194
DomainSLIDE

SMARCA5 SMARCA1

7.11e-0521582PF09111
DomainHAND

SMARCA5 SMARCA1

7.11e-0521582PF09110
DomainISWI

SMARCA5 SMARCA1

7.11e-0521582IPR029915
DomainSANT

SMARCA5 MIDEAS MYSM1 SMARCA1

8.62e-05281584PS51293
DomainZU5

MACC1 ANK2 ANK3

1.24e-04121583PF00791
DomainZU5_dom

MACC1 ANK2 ANK3

1.24e-04121583IPR000906
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH2 DNAH7

2.02e-04141583IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH2 DNAH7

2.02e-04141583IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH2 DNAH7

2.02e-04141583IPR013602
DomainDHC_N2

DNAH10 DNAH2 DNAH7

2.02e-04141583PF08393
DomainMT

DNAH10 DNAH2 DNAH7

2.02e-04141583PF12777
DomainAAA_8

DNAH10 DNAH2 DNAH7

2.02e-04141583PF12780
DomainMyb_DNA-binding

SMARCA5 TERF1 MIDEAS MYSM1

2.10e-04351584PF00249
DomainCRIC

CNKSR1 CNKSR2

2.12e-0431582PS51290
DomainDBINO

SMARCA5 SMARCA1

2.12e-0431582IPR020838
DomainCRIC_domain

CNKSR1 CNKSR2

2.12e-0431582IPR017874
DomainCRIC_ras_sig

CNKSR1 CNKSR2

2.12e-0431582PF10534
DomainDBINO

SMARCA5 SMARCA1

2.12e-0431582PF13892
DomainDHC_fam

DNAH10 DNAH2 DNAH7

2.51e-04151583IPR026983
DomainDynein_heavy

DNAH10 DNAH2 DNAH7

2.51e-04151583PF03028
DomainDynein_heavy_dom

DNAH10 DNAH2 DNAH7

2.51e-04151583IPR004273
DomainK_chnl_volt-dep_KCNQ_C

KCNQ5 KCNQ3

6.99e-0451582IPR013821
DomainK_chnl_volt-dep_KCNQ

KCNQ5 KCNQ3

6.99e-0451582IPR003937
DomainKCNQ_channel

KCNQ5 KCNQ3

6.99e-0451582PF03520
Domain-

GUF1 SUPT16H

1.45e-03715823.30.70.240
DomainEFG_V

GUF1 SUPT16H

1.45e-0371582IPR000640
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SART3 SMARCA5 RNF31 GNE ESYT1 POLR2B UBR4 ZNF185 POLR2H ACOT7 CHD7 XPO1 MTHFS NDUFA9 ATAD2 MIDEAS NSUN2 ESF1 DDX10 SART1 SRRT GUF1 ALKBH1 ARHGEF1 AHNAK SUPT16H SMARCA1 PLK1 TP53BP2 AHNAK2

1.08e-1213531623029467282
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

SART3 SMARCA5 CDK12 ZC3H18 CHD7 ZNF318 ESF1 DDX10 SART1 PAPOLA SUPT16H COIL PSPC1

9.17e-102831621330585729
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SART3 SMARCA5 ANK2 CDK12 ESYT1 ACOT7 ZNF318 NSUN2 CBS ESF1 DDX10 PAPOLA ARID2 AHNAK DDRGK1 COIL PC HERC4 ENSA TP53BP2 AHNAK2

2.92e-099341622133916271
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SART3 POLR2B UBR4 ZC3H18 MIDEAS CBS DDX10 SART1 SRRT PAPOLA SUPT16H PLK1 PSPC1

8.62e-093411621332971831
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SART3 SMARCA5 DNAH10 ACAD9 ESYT1 POLR2B UBR4 KIAA0586 XPO1 TTC3 ATAD2 NSUN2 CBS SDAD1 ESF1 DDX10 SART1 SRRT SUPT16H SMARCA1 COIL PC PSPC1 HDGF

5.23e-0814251622430948266
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SART3 ACAD9 POLR2B UBR4 E2F7 ZC3H18 XPO1 ATAD2 NSUN2 ITGB1 ESF1 UBE2R2 ARID2 SUPT16H RASEF TMEM218 MAPK6 COIL PLK1 PC HTT TBCE RAB11FIP3

6.12e-0813271622332694731
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SART3 SMARCA5 ANK2 CDK12 ESYT1 APTX CHD7 MIDEAS NSUN2 ITGB1 SDAD1 MEX3C DDX10 SRRT AKAP9 AHNAK SUPT16H SMARCA1 CCDC106 COIL PC PSPC1 MX2

1.10e-0713711622336244648
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 ANK3 RASA1 FOSL2 MYT1 DYNC2I1 WNT4 ADGRV1 TTC3 ITGB1 SFMBT2 ITPK1 PTPRB SHC2 KCNQ5 PRKAR1B RASEF IGSF9 IFT122 ARHGEF37 MAPK6 MAP2K2 HTT GULP1

1.18e-0714891622428611215
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SMARCA5 CDK12 FOSL2 KLC2 ZC3H18 CHD7 ZNF318 XPO1 ATAD2 NSUN2 HDAC7 ESF1 SART1 SRRT PAPOLA COIL MAP2K2

1.44e-077741621715302935
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SART3 MACC1 SPAG1 SMARCA5 ANK2 COL20A1 UBR4 DNAH2 CAGE1 ZNF318 TEX14 TTC3 SFMBT2 ESF1 SART1 AHNAK SUPT16H SMARCA1 DDRGK1 IFT122 MAPK6 PSPC1 CFAP46

2.67e-0714421622335575683
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

RNF31 UBR4 RNF19B TTC3 MEX3C HECW2 HERC4

3.27e-0795162729643511
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SMARCA5 ANK3 CDK12 POLR2B ZNF318 MIDEAS ESF1 ARID2 AHNAK COIL PLK1 PC TP53BP2 HTT

3.30e-075491621438280479
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SART3 SMARCA5 POLR2B ATAD2 ESF1 DDX10 SART1 SUPT16H SMARCA1 COIL PSPC1

5.05e-073321621125693804
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SART3 MACC1 CDK12 ACAD9 ESYT1 FOSL2 POLR2B APTX POLR2H CHD7 ZNF318 NDUFA9 ATAD2 SDAD1 ESF1 DDX10 SRRT GUF1 FGD4 ARID2 DDRGK1 PSPC1 MNAT1

5.12e-0714971622331527615
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ESYT1 KLC2 DNAH7 HDAC7 MEX3C LPIN3 SRRT AKAP9 KCNQ5 ARHGEF1 AHNAK PLK1 PC MAP2K2 MEX3B TP53BP2 AHNAK2

6.36e-078611621736931259
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

SMARCA5 ESYT1 XPO1 NDUFA9 ATAD2 MIDEAS NSUN2 SDAD1 ESF1 DDX10 SART1 SRRT AHNAK SUPT16H COIL PLK1 PC HDGF

9.40e-079891621836424410
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SART3 SMARCA5 XPO1 MIDEAS NSUN2 SRRT ARID2 SUPT16H PSPC1

1.01e-06220162935785414
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

ESYT1 ACOT7 XPO1 NSUN2 ITGB1 CBS SART1 SRRT PIGR SUPT16H MRPL40 PC PSPC1 TBCE

1.09e-066071621439147351
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

SART3 GNE POLR2B UBR4 POLR2H ACOT7 KLC2 XPO1 NSUN2 CBS SRRT UBE2R2 PAPOLA ARHGEF1 AHNAK SUPT16H PRKAR1B HERC4 HTT TBCE AHNAK2 HDGF

1.21e-0614551622222863883
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SART3 SMARCA5 CDK12 POLR2B UBR4 POLR2H ZC3H18 XPO1 NSUN2 ESF1 SART1 SRRT PAPOLA AHNAK SUPT16H PSPC1 MNAT1 HDGF

1.34e-0610141621832416067
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SMARCA5 WWC3 POLR2B POLR2H ACOT7 KLC2 XPO1 NSUN2 ITGB1 HDAC7 ESF1 MEX3C SART1 SRRT AKAP9 PAPOLA WDR87 MAP2K2 TP53BP2 HDGF

1.59e-0612471622027684187
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SART3 ANK2 ANK3 ACAD9 ESYT1 POLR2B UBR4 NSL1 NDUFA9 TTC3 ITGB1 ESF1 DDX10 TBC1D8 GUF1 AKAP9 SUPT16H PRKAR1B DDRGK1 MRPL40 IFT122 ENSA

1.72e-0614871622233957083
Pubmed

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.

MEX3C AGO1 MEX3B

1.96e-066162317267406
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SART3 SMARCA5 UBR4 ZC3H18 CHD7 ZNF318 XPO1 ATAD2 NSUN2 ESF1 DDX10 SART1 AHNAK COIL

2.54e-066531621422586326
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SART3 SMARCA5 CDK12 ZC3H18 CHD7 ZNF318 MIDEAS ESF1 DDX10 SART1 SRRT ARID2 AHNAK SUPT16H COIL PC PSPC1

2.55e-069541621736373674
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SART3 SMARCA5 POLR2B UBR4 POLR2H ZC3H18 XPO1 NDUFA9 NSUN2 ITGB1 CBS SART1 SRRT ARHGEF1 AHNAK SUPT16H DDRGK1 PC PSPC1 AHNAK2 HDGF

2.89e-0614151622128515276
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

SMARCA5 CDK12 POLR2B XPO1 TERF1 NSUN2 SDAD1 ESF1 DDX10 SART1 SRRT ARID2 SUPT16H COIL PLK1

2.97e-067591621535915203
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RNF31 CARMIL3 ZC3H18 HDAC7 ARHGEF1 IFT122

3.00e-0685162615449545
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SART3 ANK2 ANK3 ZNF185 ACOT7 KLC2 CNKSR2 XPO1 MTHFS NDUFA9 SRRT AGO1 FGD4 CADPS HECW2 ARHGEF1 KCNQ3 PC PSPC1 TNS1 TP53BP2

3.44e-0614311622137142655
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SMARCA5 ESYT1 POLR2B UBR4 POLR2H ACOT7 CHD7 NDUFA9 NSUN2 ITPK1 DDX10 GUF1 ARHGEF1 AHNAK SUPT16H COIL PLK1 PC MAP2K2 PSPC1

3.65e-0613181622030463901
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SART3 SPAG1 ANK3 ACAD9 ESYT1 DYNC2I1 NDUFA9 CBS HDAC7 SMYD2 ESF1 LPIN3 SART1 POSTN AHNAK SUPT16H IFT122 PLK1 TP53BP2 TBCE

3.78e-0613211622027173435
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

BDP1 SMARCA5 ANK3 ACAD9 POLR2B KLC2 XPO1 SDAD1 SART1 PTPRB ARID2 PLK1

4.12e-064971621236774506
Pubmed

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.

SART3 POLR2H MTHFS NDUFA9 UBE2R2 MAP2K2 HDGF

5.63e-06145162728846114
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

SART3 ESYT1 UBR4 POLR2H XPO1 NSUN2 SDAD1 SART1 SRRT SUPT16H DDRGK1 MAP2K2 PSPC1 TNS1

6.71e-067111621433022573
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SART3 SMARCA5 ESYT1 POLR2B ZNF318 NSUN2 SDAD1 ESF1 SRRT ARID2 SUPT16H

7.58e-064401621134244565
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

SART3 SMARCA5 POLR2B POLR2H CHD7 MEX3C SRRT SUPT16H MNAT1 MEX3B

7.63e-063581621032460013
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SART3 NAB1 ZNF185 ZNF318 ITGB1 SART1 ZNHIT6 PIGR AHNAK PC AHNAK2

8.25e-064441621134795231
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ANK3 POLR2B XPO1 ITGB1 SDAD1 ESF1 POSTN PTPRB AKAP9 AHNAK SUPT16H COIL PLK1 PC TNS1 ENSA TP53BP2

8.87e-0610491621727880917
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

SART3 SPAG1 ESYT1 POLR2B UBR4 POLR2H SART1 ZNHIT6 PSPC1

1.25e-05300162928561026
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SMARCA5 CDK12 POLR2B POLR2H ZC3H18 CHD7 XPO1 TERF1 SDAD1 SART1 SRRT AGO1 ARID2 SUPT16H MRPL40 COIL PSPC1

1.32e-0510821621738697112
Pubmed

TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.

SMARCA5 UBR4 POLR2H SMARCA1

1.67e-0533162433567268
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

SART3 SMARCA5 ZC3H18 CHD7 XPO1 MIDEAS SART1 ARID2 AHNAK SUPT16H

1.75e-053941621027248496
Pubmed

Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.

MEX3C AGO1 MEX3B

2.12e-0512162318779327
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

RASA1 UBR4 KLC2 DYNC2I1 TTC3 CBS UBE2R2 ARHGEF1 SGSM3 OSMR MAPK6 PLK1 IGSF21 TNS1 MEX3B GPRASP2 TP53BP2

2.15e-0511241621721900206
Pubmed

Role of UDP-N-acetylglucosamine2-epimerase/N-acetylmannosamine kinase (GNE) in β1-integrin-mediated cell adhesion.

GNE ITGB1

2.16e-052162224474513
Pubmed

Heart Failure Promotes Cancer Progression in an Integrin β1-Dependent Manner.

ITGB1 POSTN

2.16e-052162238139195
Pubmed

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells.

KCNQ5 KCNQ3

2.16e-052162211159685
Pubmed

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis.

XPO1 CD19

2.16e-052162231285298
Pubmed

Huntingtin interacts with cystathionine beta-synthase.

CBS HTT

2.16e-05216229466992
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

2.16e-052162215007166
Pubmed

Histamine contributes to tissue remodeling via periostin expression.

POSTN HRH1

2.16e-052162224577408
Pubmed

The localization and interactions of huntingtin.

CBS HTT

2.16e-052162210434301
Pubmed

Hyperhomocysteinemia suppresses bone marrow CD34+/VEGF receptor 2+ cells and inhibits progenitor cell mobilization and homing to injured vasculature-a role of β1-integrin in progenitor cell migration and adhesion.

ITGB1 CBS

2.16e-052162225854700
Pubmed

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor.

SART3 SART1

2.16e-052162212032085
Pubmed

Huntingtin interacts with the receptor sorting family protein GASP2.

GPRASP2 HTT

2.16e-052162216835690
Pubmed

Direct neurotransmitter activation of voltage-gated potassium channels.

KCNQ5 KCNQ3

2.16e-052162229748663
Pubmed

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

CNKSR1 CNKSR2

2.16e-052162218287031
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

2.16e-052162211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

2.16e-052162225383926
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

2.16e-052162220833135
Pubmed

A GTPase-activating protein controls Rab5 function in endocytic trafficking.

RAB41 SGSM3

2.16e-052162216086013
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SPAG1 SMARCA5 ESYT1 UBR4 ZNF185 ACOT7 ZC3H18 HMOX1 XPO1 NSUN2 ITGB1 UBE2R2 AHNAK SUPT16H PC PSPC1 ENSA AHNAK2 HDGF

2.21e-0513671621932687490
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

ESYT1 ZC3H18 CAV3 MIDEAS SDAD1 AGO1 CADPS FER1L4 MAPK6 PLK1 GPRASP2

2.30e-054961621131343991
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

SMARCA5 GNE NSUN2 CBS SUPT16H PC PSPC1

2.47e-05182162732239614
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SART3 SMARCA5 ESYT1 POLR2B ZNF185 ZC3H18 XPO1 NDUFA9 NSUN2 SDAD1 ESF1 SART1 SRRT AHNAK SUPT16H SMARCA1 COIL PSPC1

2.50e-0512571621836526897
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

GNE ACAD9 POLR2B UBR4 POLR2H SART1 ARHGEF1 AHNAK SUPT16H SMARCA1 PC PSPC1

2.72e-056011621233658012
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SART3 POLR2B ZC3H18 NSUN2 ESF1 MEX3C DDX10 SART1 SRRT AGO1 SUPT16H MRPL40 PSPC1 MEX3B

2.73e-058071621422681889
Pubmed

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

SMARCA5 POLR2B ZC3H18 SRRT AHNAK SUPT16H SMARCA1

3.03e-05188162729721183
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SMARCA5 NSL1 ZC3H18 CHD7 ATAD2 MIDEAS MYSM1 DDX10 ARID2 SUPT16H SMARCA1 HDGF

3.05e-056081621236089195
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

SART3 POLR2B UBR4 POLR2H KLC2 E2F7 CNKSR2 NDUFA9 HDAC7 SDAD1 SMYD2 SRRT TTBK2 PIGR DDRGK1 UNC79 MNAT1 ENSA

3.30e-0512841621817353931
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CNKSR1 ANK2 ANK3 UBR4 DYNC2I1 TTC3 TERF1 NSUN2 CBS SMYD2 ME3 GUF1 CADPS IFT122 SGSM3 PC MNAT1 GPRASP2

3.33e-0512851621835914814
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH2 DNAH7

3.48e-051416239373155
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

BDP1 ANK3 GNE ZNF180 KLC2 CNKSR2 HMOX1 TTC3 ATAD2 DNAH7 POSTN AHNAK HRH1 KCTD15 MRPL40 SGSM3 OSMR PSPC1

3.61e-0512931621815342556
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

SART3 SMARCA5 ANK2 ZNF318 DDX10 AHNAK SMARCA1 PSPC1

4.30e-05271162832433965
Pubmed

Tip110 protein binds to unphosphorylated RNA polymerase II and promotes its phosphorylation and HIV-1 long terminal repeat transcription.

SART3 POLR2B POLR2H

4.33e-0515162324217245
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

GNE ACAD9 UBR4 POLR2H ACOT7 E2F7 XPO1 SRRT MAP2K2 PSPC1 TBCE

4.49e-055341621135032548
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SART3 POLR2B NSUN2 ESF1 DDX10 SART1 SRRT AGO1

4.65e-05274162834244482
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANK2 ANK3 UBR4 CNKSR2 CHD7 ZNF318 TTC3 SART1 AGO1 AKAP9 SUPT16H PRKAR1B TNS1 UNC79 TP53BP2

4.81e-059631621528671696
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

CNKSR1 MXRA5 UBR4 DNAH2 CHD7 NDUFA9 DNAH7 ESF1 TTBK2 ARID2 MAP2K2 AHNAK2

4.85e-056381621231182584
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ANK3 ACAD9 POLR2B AKNAD1 CHD7 ZNF318 TTC3 ITGB1 ESF1 TTBK2 UBE2R2 PAPOLA ARHGEF1 TNS1 HERC4 RAB11FIP3

5.06e-0510841621611544199
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

SART3 SPAG1 RASA1 POLR2B XPO1 NSUN2 CBS ESF1 SART1 AHNAK PC

5.57e-055471621137267103
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

SART3 ANK2 RNF31 NAB1 KIAA0586 POLR2H KLC2 ZC3H18 TTC3 UBE2R2 FER1L4 ARID2 KCTD15 MRPL40 PC CFAP46 HDGF

5.65e-0512151621715146197
Pubmed

Human UBL5 protein interacts with coilin and meets the Cajal bodies.

SART1 COIL

6.45e-053162223726919
Pubmed

Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate.

ZC3H18 SRRT

6.45e-053162228297668
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

6.45e-053162215611082
Pubmed

Periostin activates integrin α5β1 through a PI3K/AKT‑dependent pathway in invasion of cholangiocarcinoma.

ITGB1 POSTN

6.45e-053162222735632
Pubmed

Expression of tumor-rejection antigens in gynecologic cancers.

SART3 SART1

6.45e-053162211092984
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK AHNAK2

6.45e-053162221940993
Pubmed

IL-33 Is a Cell-Intrinsic Regulator of Fitness during Early B Cell Development.

CD19 IL1RL1

6.45e-053162231391233
Pubmed

KCNQ2 is a nodal K+ channel.

ANK3 KCNQ3

6.45e-053162214762142
Pubmed

Plk1 phosphorylation of TRF1 is essential for its binding to telomeres.

TERF1 PLK1

6.45e-053162218625707
Pubmed

ARS2/SRRT: at the nexus of RNA polymerase II transcription, transcript maturation and quality control.

POLR2B SRRT

6.45e-053162234060620
Pubmed

2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells.

HMOX1 SRRT

6.45e-053162226404762
Pubmed

Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.

SMARCA5 SMARCA1

6.45e-053162221738833
Pubmed

Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.

SMARCA5 SMARCA1

6.45e-053162211359880
Pubmed

Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint.

TEX14 PLK1

6.45e-053162222405274
Pubmed

CircAHNAK1 inhibits proliferation and metastasis of triple-negative breast cancer by modulating miR-421 and RASA1.

RASA1 AHNAK

6.45e-053162231857500
Pubmed

Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation.

KCNQ5 KCNQ3

6.45e-053162212890507
Pubmed

MYSM1-dependent checkpoints in B cell lineage differentiation and B cell-mediated immune response.

MYSM1 CD19

6.45e-053162227895164
Pubmed

Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.

KCNQ5 KCNQ3

6.45e-053162218786918
InteractionRCL1 interactions

ZC3H18 XPO1 NSUN2 ESF1 SART1 HECW2 DDRGK1 PSPC1 HDGF

7.46e-071261609int:RCL1
InteractionNAA40 interactions

SART3 SMARCA5 ANK2 CDK12 ESYT1 ACOT7 KLC2 ZNF318 NSUN2 CBS ESF1 DDX10 PAPOLA ARID2 AHNAK SUPT16H DDRGK1 COIL PC PSPC1 HERC4 ENSA TP53BP2 AHNAK2

8.35e-0797816024int:NAA40
InteractionDYNC2I2 interactions

UBR4 DYNC2I1 XPO1 MAPK6 COIL MAP2K2

4.79e-06551606int:DYNC2I2
InteractionHMGB1 interactions

SMARCA5 POLR2B DYNC2I1 ZC3H18 ZNF318 XPO1 SRRT AHNAK SUPT16H SMARCA1 DDRGK1 COIL MAP2K2 MNAT1 HTT

7.99e-0648616015int:HMGB1
InteractionKDM1A interactions

SMARCA5 MYT1 POLR2B UBR4 CAGE1 CHD7 ZNF318 XPO1 NDUFA9 TERF1 SFMBT2 ZNHIT6 AKAP9 AHNAK SUPT16H COIL PC PSPC1 GPRASP2 TP53BP2 HTT

1.83e-0594116021int:KDM1A
InteractionKDR interactions

SMARCA5 RASA1 NSUN2 ITGB1 SHC2 SUPT16H SMARCA1 AHNAK2

2.68e-051501608int:KDR
InteractionH2BC21 interactions

SART3 SMARCA5 POLR2B APTX DNAH2 ZC3H18 CHD7 ATAD2 MIDEAS SFMBT2 ARID2 AHNAK SUPT16H SMARCA1 MNAT1 CFAP46 HDGF

4.03e-0569616017int:H2BC21
InteractionXRCC6 interactions

SART3 SMARCA5 RNF31 RASA1 CDK12 POLR2H ZC3H18 CHD7 ZNF318 NSUN2 ESF1 DDX10 SART1 PAPOLA SUPT16H DDRGK1 COIL PSPC1 HTT HDGF

4.81e-0592816020int:XRCC6
InteractionDNAJB6 interactions

XPO1 TEX14 NSUN2 HDAC7 DDX10 ALKBH1 SUPT16H DDRGK1 MAPK6 MAP2K2 FGD3 HTT

5.22e-0537916012int:DNAJB6
InteractionLSM7 interactions

SART3 ZBTB8B KLC2 ZC3H18 SART1 DDRGK1 MEX3B

5.44e-051221607int:LSM7
InteractionKCNQ2 interactions

ANK2 ANK3 KCNQ5 PRKAR1B KCNQ3 SNCB

5.56e-05841606int:KCNQ2
InteractionZNF330 interactions

SMARCA5 ZC3H18 CHD7 XPO1 MIDEAS SDAD1 MYSM1 ESF1 DDX10 ARID2 SUPT16H SMARCA1 COIL

5.91e-0544616013int:ZNF330
InteractionSNRPF interactions

SART3 RNF31 RASA1 POLR2B ZC3H18 MND1 SART1 SRRT PIGR DDRGK1 COIL HDGF

6.06e-0538516012int:SNRPF
InteractionPWP2 interactions

ZC3H18 XPO1 NSUN2 SDAD1 ESF1 HECW2 DDRGK1 HDGF

7.10e-051721608int:PWP2
Cytoband2q32.3-q33

NAB1 GULP1

1.24e-05216222q32.3-q33
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

BDP1 SMARCA5 CHD7 TERF1 MIDEAS MYSM1 SMARCA1

3.99e-08531147532
GeneFamilyDyneins, axonemal

DNAH10 DNAH2 DNAH7

1.56e-04171143536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD4 ARHGEF1 ARHGEF37 FGD3

8.00e-04661144722
GeneFamilyImmunoglobulin like domain containing

MXRA5 CCDC141 CD19 IGSF9 IL1RL1 IGSF21

1.41e-031931146594
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

CNKSR1 RASA1 CNKSR2 FGD4 CADPS FGD3

1.96e-032061146682
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 ANK3 DNAH10 DNAH2 DYNC2I1 ADGRV1 DNAH7 TBC1D8 CFAP221 CFAP46 MAP3K19 AHNAK2

3.29e-1319316213ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

2.71e-0919516210649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

2.71e-0919516210129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

2.71e-09195162103e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DNAH10 DNAH2 DYNC2I1 DNAH7 TBC1D8 AKAP9 CFAP46 MAP3K19

2.99e-091971621091637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DNAH10 DNAH2 DYNC2I1 DNAH7 TBC1D8 AKAP9 CFAP46 MAP3K19

2.99e-091971621022c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DNAH10 DNAH2 DYNC2I1 DNAH7 TBC1D8 AKAP9 CFAP46 MAP3K19

2.99e-09197162103bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DNAH10 DNAH2 DYNC2I1 DNAH7 TBC1D8 AKAP9 CFAP46 MAP3K19

2.99e-091971621087db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 SPAG1 ERICH3 ANK3 DNAH7 AKAP9 PIGR AHNAK CFAP46 MAP3K19

3.14e-0919816210d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ERICH3 DNAH10 DNAH2 DNAH7 PIGR CFAP221 CFAP46 MAP3K19 AHNAK2

3.58e-081911629ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ERICH3 DNAH10 DNAH2 DNAH7 PIGR CFAP221 CFAP46 MAP3K19 AHNAK2

3.58e-0819116296228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

SOX5 ERICH3 ANK3 ADGRV1 PIGR CFAP221 RASEF OSMR CFAP46

3.75e-0819216290644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 ANK2 SEC11C WNT4 ADGRV1 DNAH7 TBC1D8 FGD4 RASEF

3.75e-081921629b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

3.92e-081931629ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP46 MAP3K19

4.09e-0819416294a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SOX5 ERICH3 DCDC1 ANK3 DNAH10 DNAH7 PIGR CFAP221 CFAP46

4.28e-081951629fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SOX5 ERICH3 DCDC1 ANK3 DNAH10 DNAH7 PIGR CFAP221 CFAP46

4.28e-08195162921dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SOX5 ERICH3 DCDC1 ANK3 DNAH10 DNAH7 PIGR CFAP221 CFAP46

4.28e-081951629eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

SPAG1 ERICH3 DNAH10 DNAH2 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

4.47e-081961629de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPAG1 ERICH3 DCDC1 DNAH10 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

4.67e-08197162971fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 DCDC1 DNAH10 DNAH2 DYNC2I1 DNAH7 AKAP9 CFAP221 CFAP46

4.67e-08197162974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

ERICH3 DNAH10 DNAH2 DNAH7 PIGR CFAP221 RASEF CFAP46 MAP3K19

4.67e-08197162918fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 ANK3 CNKSR2 KCNQ5 CADPS HECW2 KCNQ3 UNC79 MNAT1

5.32e-08200162948d801219bc771d6c7e151dc88ca4c179988de85
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CARMIL3 E2F7 CAGE1 MND1 CD19 KCNQ3 GULP1 RAB11FIP3

2.32e-071721628e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPAG1 ERICH3 DCDC1 DNAH10 E2F7 DNAH7 CFAP46 MAP3K19

3.42e-071811628dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

SOX5 ANK3 ADGRV1 CCDC141 PIGR KCNQ3 RASEF OSMR

3.72e-0718316288e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

4.04e-0718516285e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

4.21e-07186162876033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

4.21e-07186162885787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL20A1 MYT1 SEC11C CHD7 ADGRV1 POSTN FGD4 GULP1

4.38e-071871628dfc2b95d70daf533bc0cc4ce78af9f65dd75a25b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

4.57e-071881628803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DNAH10 E2F7 DNAH7 TBC1D8 CFAP46 MAP3K19

5.15e-071911628683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

5.35e-071921628be592e661367affced9ebe80849b466e6adb3a34
ToppCellControl-B_intermediate-10|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX5 ANK2 ANK3 MYT1 CD19 PIGR FGD4 SNCB

5.35e-071921628224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCellmulticiliated|World / shred by cell class for turbinate

SPAG1 ERICH3 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

5.35e-0719216280f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

5.35e-071921628354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

5.57e-071931628e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

5.57e-0719316280b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 CARMIL3 ESYT1 UBR4 WNT4 SLC38A10 CADPS PC

5.57e-071931628fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

5.79e-071941628756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 ERICH3 DCDC1 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

5.79e-071941628b4ce60c06568123008b1081d644733cb91c28f51
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

5.79e-0719416281ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG1 ERICH3 DCDC1 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

5.79e-0719416287a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 ERICH3 ANK2 SEC11C WNT4 ADGRV1 FGD4 CADPS

5.79e-071941628b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

5.79e-07194162843be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

6.02e-0719516280e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 TBC1D8 CFAP46 MAP3K19

6.02e-07195162879dc031258579ea328181dda33710dd897f1064a
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH7 PIGR CFAP221 CFAP46 MAP3K19

6.02e-07195162834e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.02e-0719516283486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.02e-071951628e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ERICH3 DCDC1 DNAH7 PIGR CFAP221 CFAP46 MAP3K19

6.02e-0719516289651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-07196162827b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

ERICH3 DCDC1 ANK3 DNAH7 PIGR CFAP221 OSMR CFAP46

6.26e-071961628af4cdc61830685a888a1209826c23bcf54a43084
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-071961628686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-07196162867aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-071961628ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-0719616281cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

ERICH3 DCDC1 ANK3 DNAH7 PIGR CFAP221 OSMR CFAP46

6.26e-0719616286d02d494196e3f857d53eea46d9419690d43beca
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-071961628d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

ERICH3 DCDC1 ANK3 DNAH10 DNAH7 CFAP221 RASEF CFAP46

6.26e-07196162887d9881cfec461a5d89b688a83749b618c519485
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.26e-07196162869f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

6.76e-071981628ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK3 TTC3 KCNQ5 CADPS HECW2 KCNQ3 UNC79 MNAT1

6.76e-0719816280ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.02e-0719916282de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCelldistal-Epithelial-Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.02e-07199162818ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCelldistal-Epithelial-Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.02e-0719916286ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-07200162852aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-07200162855c148238d5c80c1faa3428a917ae8075be2c145
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

MYT1 NAB1 CHD7 ATAD2 CBS SNCB PLK1 HDGF

7.29e-0720016287c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-07200162831d75c26055177d656df1fbb10b764cebd61e122
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-072001628721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

RCSD1 XPO1 TTC3 ITGB1 AKAP9 FGD4 AHNAK SUPT16H

7.29e-072001628e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-0720016285abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-072001628e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-0720016289c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-072001628f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-072001628d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPAG1 ERICH3 DCDC1 DNAH10 DNAH7 CFAP221 CFAP46 MAP3K19

7.29e-072001628cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellControl-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX5 ANK2 ANK3 CD19 PIGR FGD4 SNCB

2.20e-061621627aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

SOX5 MACC1 ANK2 CCDC141 CD19 PIGR SNCB

2.39e-061641627746833f74095c0f25ce76baf1069f1848c231933
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CARMIL3 CAGE1 TEX14 CD19 KCNQ3 GULP1 RAB11FIP3

2.59e-061661627f4698fd08965936d51695d571bd10fb77330d916
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

CARMIL3 ACOT7 E2F7 CAGE1 MND1 TEX14 RAB11FIP3

2.69e-0616716277efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH10 DYNC2I1 DNAH7 CFAP221 CFAP46 MAP3K19

2.91e-061691627fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP221 CFAP46

2.91e-06169162714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 DCDC1 DNAH7 PIGR CFAP221 CFAP46 MAP3K19

3.81e-061761627dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

4.10e-061781627255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1 CNKSR2 SHC2 CADPS SMARCA1 PRKAR1B GPRASP2

4.10e-06178162730ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 DNAH10 DYNC2I1 DNAH7 TBC1D8 CFAP46 MAP3K19

4.41e-0618016271f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

SOX5 ANK3 ADGRV1 CCDC141 CFAP221 KCNQ3 RASEF

4.41e-061801627198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERICH3 ANK2 MYT1 CNKSR2 CHD7 KCNQ5 CADPS

4.58e-0618116277f99002a6411117cc2361334c7c9228e20c574b4
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

4.75e-061821627fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ANK3 ADGRV1 CCDC141 PIGR CFAP221 KCNQ3 RASEF

5.10e-061841627369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.10e-0618416275daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.28e-061851627f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.28e-06185162730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.28e-0618516273e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.28e-06185162718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.47e-061861627f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.67e-0618716279e10ed56090d82589bc457788282f664b70ace4b
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

ERICH3 DCDC1 DNAH10 DNAH2 DNAH7 CFAP46 MAP3K19

5.87e-06188162761a459f3fe57e5728efc72637ff2edc2d343492b
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

KCNQ5 KCNQ3 MX2

4.06e-05131573DOID:0112202 (implicated_via_orthology)
DiseaseRomano-Ward Syndrome

ANK2 CAV3 AKAP9

7.87e-05161573C0035828
DiseaseX-linked Aarskog syndrome (implicated_via_orthology)

FGD4 FGD3

1.68e-0441572DOID:6683 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease type 4H (implicated_via_orthology)

FGD4 FGD3

1.68e-0441572DOID:0110192 (implicated_via_orthology)
Diseasefrailty measurement

ANK3 MAPK6 HTT

2.42e-04231573EFO_0009885
Diseasecortical surface area measurement

SOX5 DCDC1 ANK3 MYT1 RCSD1 CHD7 MND1 WNT4 ADGRV1 XPO1 DNAH7 CADPS PAM IGSF9 MAPK6 PC TNS1 MNAT1

3.04e-04134515718EFO_0010736
Diseaseneuroimaging measurement

SOX5 DCDC1 ANK3 CNKSR2 CHD7 XPO1 CADPS ARHGEF1 IGSF9 TMEM218 MAPK6 PC TNS1 MNAT1 HTT

6.10e-04106915715EFO_0004346
Diseaseintellectual disability (implicated_via_orthology)

ANK2 UBR4 NSUN2 GPRASP2

6.99e-04751574DOID:1059 (implicated_via_orthology)
Diseasechronotype measurement

SOX5 ANK2 ANK3 RASA1 NAB1 SEC11C ZNF318 TEX14 CAV3 HECW2 ARID2 PC ENSA

9.08e-0488215713EFO_0008328
Diseasesystemic scleroderma

SOX5 ESYT1 NAB1 CHD7

1.12e-03851574EFO_0000717
Diseaselong QT syndrome (implicated_via_orthology)

KCNQ5 KCNQ3

1.23e-03101572DOID:2843 (implicated_via_orthology)
DiseaseCongenital long QT syndrome

CAV3 AKAP9

1.50e-03111572cv:C1141890
DiseaseNon-Small Cell Lung Carcinoma

MXRA5 E2F7 ITGB1 OSMR MAP2K2

1.51e-031561575C0007131
Diseasechildhood gender nonconformity

FOSL2 MYSM1 PC

1.56e-03431573EFO_0020103
DiseaseLong QT syndrome

CAV3 AKAP9

1.79e-03121572cv:C0023976
DiseasePrimary Ciliary Dyskinesia

SPAG1 CFAP221 IFT122

2.02e-03471573C4551720
DiseaseCoffin-Siris syndrome

ARID2 SMARCA1

2.11e-03131572C0265338
DiseaseShort Rib-Polydactyly Syndrome

KIAA0586 DYNC2I1

2.11e-03131572C0036996
DiseaseSaldino-Noonan Syndrome

KIAA0586 DYNC2I1

2.45e-03141572C0036069
DiseaseMajewski Syndrome

KIAA0586 DYNC2I1

2.45e-03141572C0024507
Diseaseasthma exacerbation measurement, response to corticosteroid

ACOT7 ME3 KCNQ3

2.55e-03511573EFO_0007614, GO_0031960
DiseaseNeoplasm Invasiveness

HMOX1 ITGB1 ITPK1 AHNAK TP53BP2

3.10e-031841575C0027626
Diseasecolorectal mucinous adenocarcinoma

SOX5 CCDC141

3.21e-03161572EFO_0009361
Diseasecentral nervous system disease (implicated_via_orthology)

SMARCA5 SMARCA1

3.21e-03161572DOID:331 (implicated_via_orthology)
DiseaseIdiopathic hypogonadotropic hypogonadism

CHD7 CCDC141

4.07e-03181572C0342384
Diseaselongevity

NAB1 CNKSR2 SDAD1 SLC38A10 MEX3B FGD3

4.25e-032841576EFO_0004300
Diseaseuterine fibroid

DNAH2 WNT4 TNS1 MEX3B GULP1

4.33e-031991575EFO_0000731
DiseaseColorectal Carcinoma

ANK2 ZBTB8B CNKSR2 POSTN ZNHIT6 AKAP9 KCNQ5 ARHGEF1 HRH1 IGSF21

4.48e-0370215710C0009402
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

RASA1 MAP2K2

4.53e-03191572C3501846
DiseaseNoonan syndrome-like disorder with loose anagen hair

RASA1 MAP2K2

4.53e-03191572C1843181
DiseaseCardio-facio-cutaneous syndrome

RASA1 MAP2K2

4.53e-03191572C1275081
DiseaseCostello syndrome (disorder)

RASA1 MAP2K2

4.53e-03191572C0587248
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

DNAH2 ITPK1

5.02e-03201572EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
DiseaseTinnitus

E2F7 ZNF318 WNT4 ITPK1

5.22e-031301574HP_0000360

Protein segments in the cluster

PeptideGeneStartEntry
QLVPETEDEKKRFEE

ACOT7

346

O00154
TQEKEGILPERAEEA

ENSA

21

O43768
AEQPELAEEFTEKRE

ERICH3

816

Q5RHP9
HEVPGQEIEVEVFDK

ESYT1

391

Q9BSJ8
VPGQELEVEVFDKDL

ESYT1

711

Q9BSJ8
SRKDFEEEDVILQPE

BDP1

756

A6H8Y1
EREVSPQENGLEEVK

BDP1

1041

A6H8Y1
EFGEENLPKEETEFL

AKAP9

1291

Q99996
GQNTEEPTEREKVEL

ARHGEF1

576

Q92888
DNEKEGFPITAIREI

CDK12

761

Q9NYV4
EKEVTAEGVERPEIV

CAGE1

251

Q8TC20
EPIEDEKRDISTEGF

ALKBH1

356

Q13686
QEAGLIPRTEDKEFD

ARHGEF37

256

A1IGU5
LGPVEKFFTEEVDSR

ACAD9

71

Q9H845
VDFEVTIPGEGKDRI

AGO1

111

Q9UL18
TARERDFIPVEKGET

ADGRV1

1046

Q8WXG9
LVFRDFTDEKEGPIT

ARID2

1751

Q68CP9
IVEFEEEAKNPGLET

APTX

111

Q7Z2E3
IGSEPEGLQVEEKER

CFAP46

2246

Q8IYW2
EVKGERVQNEEVGPE

RCSD1

316

Q6JBY9
GREVDVNLPKADIDV

AHNAK

1271

Q09666
QPKREEEEVLDQGDF

PAM

376

P19021
FPEDTVEQKAESVGR

ACSF2

421

Q96CM8
GEIFNVQLPDKEERT

ATAD2

916

Q6PL18
QQESVDAEGPVVEKI

CHD7

791

Q9P2D1
RVLEQAEGKVEEPEN

CHD7

2166

Q9P2D1
VILAQEEEGVEKPAE

DDRGK1

96

Q96HY6
ALDQVDDGEVPLREK

TP53BP2

436

Q13625
EEKAEGLPVVTREDV

CCDC83

81

Q8IWF9
DAKELEAIFGRPVVD

MAP2K2

271

P36507
GREVAKEFDQLTPEE

RCN3

61

Q96D15
ADLSPEREVQAVEGK

RHEBL1

121

Q8TAI7
PENKEVEEERIAGTE

OSMR

526

Q99650
VEEVGREEDPHEGKI

RASA1

336

P20936
GDEAKFIPREEQVST

RASEF

136

Q8IZ41
PKEGTVEIELESFEE

RAB41

201

Q5JT25
EGPEEDIADKVVFLE

RAB11FIP3

456

O75154
DSFKIRPLGFTEEVE

ITGB1

441

P05556
ADPERVENQIEKVFD

GUF1

201

Q8N442
ELEDLEVDGQKVEVP

NSUN2

101

Q08J23
GEPFEIVERVKEDLE

ANK2

1546

Q01484
NEEVFGQITERELKP

HECW2

1376

Q9P2P5
FVQKLGDALPEEIRE

NSL1

56

Q96IY1
DGIGTVTVEEKERFE

CADPS

766

Q9ULU8
EIETEEIIKDIFQRG

MTHFS

61

P49914
VAIFGEEKQVTEPEE

DCDC1

1066

M0R2J8
REKVVDIELNGEPVD

LPIN3

61

Q9BQK8
VVREADGSDELKPEQ

PTPRB

1491

P23467
ELDKIEGVFERPSDE

ITPK1

246

Q13572
RLVETKDSIGDEDPF

IFT122

1136

Q9HBG6
QLFEDPTVDKEVEIR

MNAT1

61

P51948
RIKVEDGFPDFQDSV

NAB1

331

Q13506
SRVPFSGLKEEEEED

ATXN8OS

16

P0DMR3
EEEEEGFFQKVLTPL

ATXN8OS

36

P0DMR3
LVEKDVPEVDAQGEE

KCNQ3

281

O43525
ESKLFITDEEVGPEE

KCNQ5

866

Q9NR82
FELLTVEEAEKRPVG

FER1L4

1706

A9Z1Z3
DGEEEKEGTLFPERT

CARMIL3

1246

Q8ND23
RPGGEETVEIEKEET

DYNC2I1

346

Q8WVS4
DGTSPEEEIEIERQK

ESF1

691

Q9H501
EEEVQVDPRKYLDGD

MAPK6

391

Q16659
FEENKIDRTFGIPED

MND1

186

Q9BWT6
PLEERGAETETKVQE

FGD4

166

Q96M96
GIDEEIVLEPRKSDF

HERC4

16

Q5GLZ8
EGEEKEAATLEVERP

HDGF

176

P51858
KRAFQLEEGEETEPD

COIL

111

P38432
EEDIVNPANELIKEG

FGD3

361

Q5JSP0
FLVEPEGIEKERTQS

OVOS2

891

Q6IE36
VGEKVVRDAFPEAII

NDUFA9

186

Q16795
FPREEKLSQDEIVLG

KLC2

6

Q9H0B6
LKPFGVFEEEEELQR

PAPOLA

46

P51003
EEVKDLRAVEEAFVP

PAPOLA

141

P51003
EDIRKTFEINPISGE

PCDHB14

286

Q9Y5E9
EEITGPVDEETFLKA

ANKRD2

141

Q9GZV1
KFVLRDEATEPGDQE

HTT

646

P42858
TKITDFGEPRIQQEE

IL1RL1

256

Q01638
EFDGKELVLERVPAE

IGSF21

391

Q96ID5
RELEFVEQPKELGDA

CCDC141

806

Q6ZP82
VVGDSAVDEFEKQRP

E2F7

126

Q96AV8
GIKTEPEFFELDVVV

GNE

31

Q9Y223
AEVGEFDPSKERLLE

CCDC106

231

Q9BWC9
EEPLVVKVEEGDNAV

CD19

21

P15391
KGEEEEREVQVGRPE

COL20A1

506

Q9P218
AARGEIPEKLEFDQV

GUCY2F

331

P51841
EVEQPKGTEVVRDAV

GULP1

36

Q9UBP9
GIVVAQERPDLEEEK

DNAH7

3116

Q8WXX0
VEDRPEVKDENAGVL

ZNHIT6

101

Q9NWK9
EILREKGFDQAPVVD

CBS

436

P35520
VGAVVVKQEPLEEDS

FOSL2

216

P15408
TIVGDFDPERKVEGE

AKNAD1

451

Q5T1N1
EGRIDDEEPFKIVEK

ANK3

1936

Q12955
IVKVDFEDVIAEPVG

CAV3

36

P56539
DPDFEVKTEGERKEI

MACC1

441

Q6ZN28
VPEIQEKEEQEEGRE

MIDEAS

946

Q6PJG2
PEDNIKAVVVTDGER

ME3

176

Q16798
LEPVQFEDGEKIVVQ

PRKAR1B

271

P31321
LEEEIERNKESPVFA

HMOX1

61

P09601
PGRSIKDEEEETVFR

ENGASE

46

Q8NFI3
IKEVPTQFLDRDEEE

DDX10

616

Q13206
PVVFSQEDDREVDKL

HRH1

286

P35367
RVPGADKEEVEAVTA

HDAC7

911

Q8WUI4
ELPGVKEFFEHIERE

DNAH10

806

Q8IVF4
DFEEEVKPIGNVVTE

DNAH2

2576

Q9P225
LKQEVEERFNESGDP

SART3

456

Q15020
REELEQAQIKGPVDV

SLC38A10

451

Q9HBR0
LKEGNIPAVREEDID

MAP3K19

336

Q56UN5
GDPILDEEFQRLKTE

CFAP221

411

Q4G0U5
GEEPVFVVTGRKEDV

MEX3B

106

Q6ZN04
REEFPTDLKPEEVAQ

SNCB

86

Q16143
DKARERPQVELTFEE

MRPL40

96

Q9NQ50
VKIEFDEDDGPITVA

RNF19B

456

Q6ZMZ0
EDPIRAGEIVVFKVE

SEC11C

86

Q9BY50
IGEKEVIQADDEPTF

TEX14

236

Q8IWB6
DNIAREVEGKSPEEV

SMARCA1

881

P28370
REEAKPESEEEAIFG

GPRASP2

436

Q96D09
RGEEPIFVVTGRKED

MEX3C

271

Q5U5Q3
TFRLDEDGKVLTPEE

SGSM3

616

Q96HU1
KGFDQEEVFEKPTRE

POLR2B

821

P30876
IPGAEVLEVEKEENA

SDAD1

476

Q9NVU7
TKEELEFEVPFRDLG

SUPT16H

791

Q9Y5B9
RILEQEEEEEQAGKP

SRRT

266

Q9BXP5
DLEVQDGQVDVKLPE

AHNAK2

731

Q8IVF2
EEVLGDPELTGEKFR

CNKSR1

641

Q969H4
EGEVAIIDKVLDNPD

CNKSR2

966

Q8WXI2
VIEQKEVPNGLRDEA

RNF31

971

Q96EP0
KPEEVLVVENDQGEV

XPO1

426

O14980
KVIPDVEDEGARVND

TTLL8

86

A6PVC2
DPEGVVRTKDVLFES

SHC2

536

P98077
LEDGPEEDRKEQIVT

TBCE

91

Q15813
VGNLPTDITEEDFKR

PSPC1

86

Q8WXF1
EKALIEEVFPETGDV

KCTD15

186

Q96SI1
TEVPKDVTVREGDDI

VSTM2B

31

A6NLU5
AEQEEEPEKFREALV

TBC1D8

131

O95759
IEIQEVNEGKEEPGR

SPAG1

756

Q07617
VVREFENLPGETEEK

TTBK2

766

Q6IQ55
QPEEDEGKVVVRLSE

TNS1

1006

Q9HBL0
PEGTEDTKQEEEERL

SFMBT2

801

Q5VUG0
EFFPEETRQILEKAG

TTC3

1136

P53804
FEDIFDVKDIDPEGK

POLR2H

6

P52434
KEAEEVFERIFGDPN

TERF1

191

P54274
APDEKVLDSGFREIE

PIGR

581

P01833
IERPKEEYFQEVGRE

IGSF9

421

Q9P2J2
EDEDPERKGAIVFNA

SART1

541

O43290
ALEVKERDDLVPFTG

TMOD4

76

Q9NZQ9
QRIFDEEPANGVKIE

ZNF180

126

Q9UJW8
EKFDGATEVEPRRVG

WNT4

236

P56705
RQKVEEEESDGLPAF

SOX5

36

P35711
PEVEVKIVDDFFIGR

TMEM218

66

A2RU14
ELKSLQEEPVEGFRI

UBE2R2

16

Q712K3
EGEPEFRLIKEGETI

POSTN

706

Q15063
ENIAREVEGKTPEEV

SMARCA5

866

O60264
LAEVRAVQEIKPGEE

SMYD2

221

Q9NRG4
EGKDLDPEVFQRLVI

UBR4

2561

Q5T4S7
EGGIEEEEVIPFLKR

WDR87

2181

Q6ZQQ6
GPKIAEEFEVELERG

PC

1041

P11498
PKTLVLDFETEGERN

ZNF318

2076

Q5VUA4
QAPFIAKRVEVVEED

ZNF185

211

O15231
GVFEPLTKRNEDAEE

WWC3

576

Q9ULE0
EEVKFPGTNFDEIID

KIAA0586

846

Q9BVV6
QEPDFEEKRFTVTIG

ZC3H18

321

Q86VM9
EDGAEESEFKIQIVP

UNC79

1821

Q9P2D8
REKEEPVVRETGEVV

PLK1

356

P53350
RIEPKVEFDADEVEV

ZBTB8B

226

Q8NAP8
TELELQDPGQVEKEI

MX2

176

P20592
EKEPETNVAEGRRVF

MXRA5

751

Q9NR99
IQEEEKQAIPEFFEG

MYSM1

386

Q5VVJ2
EKGLFIQPEDAEEVV

MYT1

211

Q01538