Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopolyphosphatase activity	NUDT11 NUDT10	1.17e-04	5	69	2	GO:0000298
GeneOntologyMolecularFunction	bis(5'-adenosyl)-hexaphosphatase activity	NUDT11 NUDT10	1.17e-04	5	69	2	GO:0034431
GeneOntologyMolecularFunction	diphosphoinositol-polyphosphate diphosphatase activity	NUDT11 NUDT10	1.17e-04	5	69	2	GO:0008486
GeneOntologyMolecularFunction	bis(5'-adenosyl)-pentaphosphatase activity	NUDT11 NUDT10	1.75e-04	6	69	2	GO:0034432
GeneOntologyBiologicalProcess	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901910
GeneOntologyBiologicalProcess	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901911
GeneOntologyBiologicalProcess	diadenosine pentaphosphate catabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901907
GeneOntologyBiologicalProcess	diadenosine pentaphosphate metabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901906
GeneOntologyBiologicalProcess	diadenosine hexaphosphate catabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901909
GeneOntologyBiologicalProcess	diadenosine hexaphosphate metabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:1901908
GeneOntologyBiologicalProcess	diphosphoinositol polyphosphate metabolic process	NUDT11 NUDT10	1.16e-04	5	71	2	GO:0071543
GeneOntologyBiologicalProcess	diadenosine polyphosphate catabolic process	NUDT11 NUDT10	1.74e-04	6	71	2	GO:0015961
MousePheno	decreased spinal cord ventral horn cell number	MORC2 DYNC1H1	1.69e-05	2	58	2	MP:0005113
MousePheno	heart left atrium hypoplasia	CARM1 SMG9	5.06e-05	3	58	2	MP:0010647
MousePheno	decreased heart left atrium size	CARM1 SMG9	5.06e-05	3	58	2	MP:0031578
MousePheno	abnormal optic nerve morphology	FAM161A PPFIA2 LPP SMG9 MORC2 RUNDC1	1.04e-04	182	58	6	MP:0001330
MousePheno	abnormal heart development	CARM1 NCOR2 VCAN SMG9 ITGA4 MORC2 SPEN RFX3	1.40e-04	372	58	8	MP:0000267
Domain	Liprin	PPFIA4 PPFIA2	2.06e-04	6	70	2	IPR029515
Domain	NUDIX_hydrolase_CS	NUDT11 NUDT10	8.92e-04	12	70	2	IPR020084
Domain	FH2	FMN1 FMNL1	1.41e-03	15	70	2	PS51444
Domain	FH2_Formin	FMN1 FMNL1	1.41e-03	15	70	2	IPR015425
Domain	FH2	FMN1 FMNL1	1.41e-03	15	70	2	PF02181
Domain	FH2	FMN1 FMNL1	1.41e-03	15	70	2	SM00498
Domain	Myosin_tail_1	MYO18A MYH15	2.04e-03	18	70	2	PF01576
Domain	Myosin_tail	MYO18A MYH15	2.04e-03	18	70	2	IPR002928
Domain	Myosin-like_IQ_dom	MYO18A MYH15	2.27e-03	19	70	2	IPR027401
Domain	-	MYO18A MYH15	2.27e-03	19	70	2	4.10.270.10
Domain	-	SACS MORC2	2.52e-03	20	70	2	3.30.565.10
Domain	HATPase_C	SACS MORC2	2.78e-03	21	70	2	IPR003594
Domain	NUDIX_BOX	NUDT11 NUDT10	3.62e-03	24	70	2	PS00893
Domain	NUDIX	NUDT11 NUDT10	3.62e-03	24	70	2	PF00293
Domain	NUDIX	NUDT11 NUDT10	4.25e-03	26	70	2	PS51462
Domain	-	NUDT11 NUDT10	4.91e-03	28	70	2	3.90.79.10
Domain	NUDIX_hydrolase_dom-like	NUDT11 NUDT10	4.91e-03	28	70	2	IPR015797
Domain	NUDIX_hydrolase_dom	NUDT11 NUDT10	5.27e-03	29	70	2	IPR000086
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	NRXN2 PPFIA4 PPFIA2 RTN3	1.15e-04	67	53	4	MM15327
Pathway	BIOCARTA_CARM_ER_PATHWAY	CARM1 NCOR2 SPEN	1.23e-04	26	53	3	M2499
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	NCOR2 PPFIA2 FRYL CCDC136 DYNC1H1 EXOC4	6.88e-07	151	71	6	17043677
Pubmed	Knockout mice with pituitary malformations help identify human cases of hypopituitarism.	SMG9 MORC2 PLXNB2 RUNDC1	2.23e-06	45	71	4	38822427
Pubmed	An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.	NUDT11 NUDT10	4.11e-06	2	71	2	12105228
Pubmed	Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.	NUDT11 NUDT10	4.11e-06	2	71	2	12689335
Pubmed	The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments.	FMN1 FMNL1	4.11e-06	2	71	2	14990563
Pubmed	Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.	FMN1 FMNL1	4.11e-06	2	71	2	16480715
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 TSC22D1 SACS PPFIA4 MORC2 MGA RSPRY1 EXOC4	7.50e-06	493	71	8	15368895
Pubmed	Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.	NCOR2 SPEN	1.23e-05	3	71	2	24268649
Pubmed	Fibulin-1 Integrates Subendothelial Extracellular Matrices and Contributes to Anatomical Closure of the Ductus Arteriosus.	VCAN PTGER4	1.23e-05	3	71	2	32640908
Pubmed	Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.	NUDT11 NUDT10	1.23e-05	3	71	2	12121577
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 RC3H2 MYO18A SMG9 MORC2 SPEN MGA EXOC4 CEP55	1.65e-05	724	71	9	36232890
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CEP350 SACS MGA DYNC1H1	1.83e-05	76	71	4	27542412
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	NCOR2 RC3H2 MISP SEC24B MYO18A MORC2 MGA DYNC1H1 EXOC4	2.26e-05	754	71	9	35906200
Pubmed	Defining the membrane proteome of NK cells.	CEP350 NCOR2 MIA3 MTHFD1 MYO18A NUP188 ITGA4 FMNL1 DYNC1H1 EXOC4 CEP55	2.36e-05	1168	71	11	19946888
Pubmed	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.	NCOR2 SPEN	2.46e-05	4	71	2	16129689
Pubmed	Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.	NUDT11 NUDT10	2.46e-05	4	71	2	12370170
Pubmed	Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.	NCOR2 SPEN	2.46e-05	4	71	2	15062576
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MISP NRXN2 SACS MTHFD1 HECW2 PPFIA4 PPFIA2 VCAN MYO18A RTN3 DYNC1H1 EXOC4	3.04e-05	1431	71	12	37142655
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF502 NCOR2 TSC22D1 MIA3 RTN3 NUP188 MGA PLXNB2 RSPRY1 ZNF697 EXOC4	3.10e-05	1203	71	11	29180619
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	PPFIA4 PPFIA2 EXOC4	3.18e-05	30	71	3	16186258
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CEP350 STAC2 ELOA2 SACS PPFIA4 MYO18A SPEN CCDC136	3.37e-05	608	71	8	16713569
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	CEP350 CSN2 MTHFD1 DYNC1H1 EXOC4	3.66e-05	182	71	5	31067453
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP350 NCOR2 SEC24B SPEN MGA	3.85e-05	184	71	5	32908313
Pubmed	Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.	NUDT11 NUDT10	4.09e-05	5	71	2	18264098
Pubmed	Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte.	TRPC6 TRPM1	4.09e-05	5	71	2	16857711
Pubmed	Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1.	NCOR2 SPEN	4.09e-05	5	71	2	15778499
Pubmed	The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.	PPFIA4 PPFIA2	4.09e-05	5	71	2	19013515
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 LUC7L3 SACS MTHFD1 NUP188 SPEN MGA PLXNB2 DYNC1H1 LGALS3BP	4.25e-05	1024	71	10	24711643
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOR2 ZFAND3 TSC22D1 MIA3 LUC7L3 PPFIA2 TBCK LPP SLX4IP RTN3 FRYL EXOC4	4.47e-05	1489	71	12	28611215
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCOR2 SETX SLMAP MORC2 SPEN MGA RFX3 DYNC1H1 LGALS3BP	6.10e-05	857	71	9	25609649
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MISP MIA3 SETX MTHFD1 SEC24B BAG1 RTN3 NUP188 PLXNB2 DYNC1H1 LGALS3BP	6.11e-05	1297	71	11	33545068
Pubmed	The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.	NCOR2 SPEN	6.13e-05	6	71	2	25915022
Pubmed	Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.	PPFIA4 PPFIA2	6.13e-05	6	71	2	21618221
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZFAND3 MIA3 SETX MTHFD1 FMN1 VCAN LPP FRYL NUP188 MGA	6.84e-05	1084	71	10	11544199
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 RC3H2 MISP MIA3 LPP	7.05e-05	209	71	5	36779422
Pubmed	The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.	NCOR2 SPEN	8.57e-05	7	71	2	11867749
Pubmed	Elongator and codon bias regulate protein levels in mammalian peripheral neurons.	SETX VCAN	8.57e-05	7	71	2	29497044
Pubmed	Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.	PPFIA4 PPFIA2	8.57e-05	7	71	2	11931740
Pubmed	An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.	SEC24B PLXNB2	1.14e-04	8	71	2	21559415
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	LPP SEC24B SPEN MGA DYNC1H1 EXOC4 CEP55	1.31e-04	549	71	7	38280479
Pubmed	Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.	FMN1 FMNL1	1.47e-04	9	71	2	17554679
Pubmed	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.	PPFIA4 PPFIA2	1.47e-04	9	71	2	12923177
Pubmed	Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.	PPFIA4 PPFIA2	1.47e-04	9	71	2	12629171
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RGPD2 ELOA2 SACS FAM161A PPFIA4 PPFIA2 BAG1 MYO18A MYH15 SPEN CCDC158	1.56e-04	1442	71	11	35575683
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CEP350 RC3H2 MIA3 SLMAP CEP55	1.66e-04	251	71	5	29778605
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 SETX MTHFD1 SEC24B MUC16 SPEN MGA DYNC1H1	1.84e-04	777	71	8	35844135
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MIA3 LPP SEC24B EXOC4 CEP55	2.06e-04	263	71	5	34702444
Pubmed	Versican interacts with chemokines and modulates cellular responses.	VCAN ITGA4	2.23e-04	11	71	2	11083865
Pubmed	Multiple newly identified loci associated with prostate cancer susceptibility.	NUDT11 NUDT10	2.23e-04	11	71	2	18264097
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	CARM1 SEC24B	2.23e-04	11	71	2	23968836
Pubmed	Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.	NCOR2 SPEN	2.23e-04	11	71	2	11331609
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	CARM1 LUC7L3 MTHFD1 LPP MYO18A DYNC1H1 EXOC4	2.27e-04	601	71	7	33658012
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MISP COL17A1 MTHFD1 SLMAP MYO18A ITGA4 SPEN DYNC1H1 LGALS3BP CEP55	2.29e-04	1257	71	10	36526897
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CEP350 FAM161A DYNC1H1 CEP55	2.33e-04	146	71	4	21399614
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	TSC22D1 LUC7L3 LRRC58 MGA DYNC1H1	2.37e-04	271	71	5	25737280
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOR2 SPEN MGA RUNDC1 DYNC1H1 CEP55	2.51e-04	430	71	6	35044719
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PPFIA4 PPFIA2	2.68e-04	12	71	2	9624153
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	NCOR2 SETX LPP SEC24B SLX4IP MGA	2.98e-04	444	71	6	34795231
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	CARM1 MIA3 MTHFD1 MYO18A EXOC4	2.99e-04	285	71	5	32838362
Pubmed	Alternative splice variants encoding unstable protein domains exist in the human brain.	NRXN2 MYO18A	3.16e-04	13	71	2	15491607
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	NCOR2 SLMAP DYNC1H1 LGALS3BP	3.38e-04	161	71	4	32572027
Pubmed	Global landscape of HIV-human protein complexes.	CARM1 RTN3 ITGA4 DYNC1H1 LGALS3BP EXOC4	3.47e-04	457	71	6	22190034
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RC3H2 MIA3 SETX LUC7L3 MORC2 RSPRY1 EXOC4	3.64e-04	650	71	7	38777146
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMN1 FMNL1	3.68e-04	14	71	2	26272686
Pubmed	Validation of genome-wide prostate cancer associations in men of African descent.	NUDT11 NUDT10	4.24e-04	15	71	2	21071540
Pubmed	A human MAP kinase interactome.	CEP350 TSC22D1 SETX CSN2 MYO18A MGA	4.80e-04	486	71	6	20936779
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	MISP MTHFD1 MYO18A DYNC1H1 LGALS3BP EXOC4	4.90e-04	488	71	6	31324722
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	CARM1 NCOR2	5.48e-04	17	71	2	19183483
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NCOR2 NUP188 SPEN	5.56e-04	78	71	3	28611094
Pubmed	Human transcription factor protein interaction networks.	NCOR2 SEC24B MYO18A SLX4IP MORC2 SPEN MGA DYNC1H1 LGALS3BP EXOC4	6.27e-04	1429	71	10	35140242
Pubmed	Systematic identification of pathological lamin A interactors.	STAC2 KASH5 FAM161A RTN3 BRICD5	6.40e-04	337	71	5	24623722
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CARM1 SETX MTHFD1 HECW2 PPFIA2 NUP188 DYNC1H1	7.60e-04	736	71	7	29676528
Pubmed	mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.	PPFIA4 PPFIA2	7.62e-04	20	71	2	23791195
Pubmed	Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.	CARM1 NCOR2 NRXN2	8.16e-04	89	71	3	18950845
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CEP350 MTHFD1 SLX4IP MGA DYNC1H1	8.28e-04	357	71	5	37059091
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MIA3 SACS BAG1 SLMAP MYO18A RTN3 PLXNB2 LGALS3BP EXOC4 CEP55	8.50e-04	1487	71	10	33957083
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	MIA3 LPP SEC24B SLMAP DYNC1H1	8.60e-04	360	71	5	33111431
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO18A TRPM1 MORC2 SPEN	8.83e-04	208	71	4	33230847
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	CARM1 LUC7L3 MTHFD1 FRYL LSM11 MGA	9.22e-04	551	71	6	34728620
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PPFIA2 LPP RTN3 CEP55	1.05e-03	218	71	4	33378226
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	LUC7L3 MGA CCDC136	1.08e-03	98	71	3	34943047
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPC6 TRPM1	1.10e-03	24	71	2	33884443
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CEP350 PPFIA2 LPP SLMAP PLXNB2 DYNC1H1	1.13e-03	573	71	6	28330616
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PPFIA4 FRYL MORC2	1.14e-03	100	71	3	10048485
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	TSC22D1 LUC7L3 MTHFD1 SLMAP FRYL NUP188 DYNC1H1 LGALS3BP EXOC4	1.18e-03	1284	71	9	17353931
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPC6 TRPM1	1.20e-03	25	71	2	16382100
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	RGPD2 MYO18A RTN3 LGALS3BP	1.20e-03	226	71	4	37839992
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NRXN2 MYH15 SPEN	1.21e-03	102	71	3	10231032
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	SMG9 FRYL RUNDC1	1.25e-03	103	71	3	29539633
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	CEP350 LPP SLMAP	1.32e-03	105	71	3	19156129
Pubmed	An introduction to TRP channels.	TRPC6 TRPM1	1.40e-03	27	71	2	16460286
Pubmed	Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1.	ADGRE3 VCAN OSBPL1A	1.43e-03	108	71	3	23383108
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	LUC7L3 MTHFD1 DYNC1H1 EXOC4	1.43e-03	237	71	4	29564676
Pubmed	Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.	CARM1 NCOR2	1.50e-03	28	71	2	24880616
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	NCOR2 RTN3 SPEN	1.50e-03	110	71	3	37219487
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	PPFIA4 PPFIA2 EXOC4	1.50e-03	110	71	3	27889896
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 SETX CSN2 MORC2 SPEN MGA	1.52e-03	608	71	6	36089195
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SETX LUC7L3 NRXN2 SACS VCAN MYO18A SPEN DYNC1H1	1.61e-03	1082	71	8	38697112
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	SETX LUC7L3 HECW2 MUC16 SPEN	1.70e-03	420	71	5	28065597
Pubmed	Control of developmentally primed erythroid genes by combinatorial co-repressor actions.	NCOR2 SPEN	1.72e-03	30	71	2	26593974
Interaction	PPP2R3C interactions	CEP350 FAM161A SMG9 RTN3 DYNC1H1	7.63e-07	50	69	5	int:PPP2R3C
Interaction	SQSTM1 interactions	CEP350 CARM1 SETX MTHFD1 LPP SEC24B BAG1 SMG9 RTN3 FRYL NUP188 DYNC1H1 LGALS3BP EXOC4 CEP55	1.80e-05	1257	69	15	int:SQSTM1
Interaction	CEP63 interactions	CEP350 NCOR2 FAM161A TBCK EXOC4 CEP55	3.40e-05	179	69	6	int:CEP63
Interaction	CAPZA1 interactions	CARM1 RC3H2 TBCK SEC24B MYO18A ITGA4 DYNC1H1 EXOC4	3.49e-05	366	69	8	int:CAPZA1
Coexpression	GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_UP	CARM1 SETX COL17A1 FAM161A SPEN RUNDC1	1.74e-05	200	71	6	M9354
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP	CEP350 STAC2 LUC7L3 OSBPL1A LRRC58 MGA	1.74e-05	200	71	6	M3774
Coexpression	GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP	CARM1 ZFAND3 TSC22D1 SEC24B MYO18A DYNC1H1	1.74e-05	200	71	6	M3675
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 HECW2 TRPM1 LRRC58 PTGER4 CCDC158	4.80e-07	183	71	6	a0a3e4d07ac73dbbb1e019fd11e88ccffe6cf2ca
ToppCell	droplet-Marrow-nan-3m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 VCAN ITGA4 PLXNB2	7.95e-06	171	71	5	992df143d76f9e7fb1997a8996f61e941f0f9d4f
ToppCell	droplet-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 PTGER4 FMNL1	8.18e-06	172	71	5	f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 ITGA4 PTGER4 FMNL1	8.18e-06	172	71	5	f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ARL5C SETX PPFIA4 ITGA4	1.13e-05	184	71	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	PPFIA2 MUC16 PTGER4 RUNDC1 CCDC136	1.29e-05	189	71	5	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TBCK FRYL ITGA4 SPEN EXOC4	1.36e-05	191	71	5	9454f642c3621370fa23640b631301346b300950
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CEP350 FRYL LRRC58 MGA DYNC1H1	1.43e-05	193	71	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TSC22D1 MIA3 LUC7L3 LPP LGALS3BP	1.65e-05	199	71	5	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CEP350 SETX FRYL ITGA4 DYNC1H1	1.69e-05	200	71	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	RC3H2 VCAN SPEN EXOC4	6.45e-05	135	71	4	b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TSC22D1 PPFIA4 PPFIA2 TRPC6	1.18e-04	158	71	4	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLX4IP ITGA4 FMNL1 CEP55	1.18e-04	158	71	4	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM161A PPFIA4 TRPC6 PTGER4	1.21e-04	159	71	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM161A PPFIA4 TRPC6 PTGER4	1.21e-04	159	71	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.21e-04	159	71	4	cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM161A PPFIA4 TRPC6 PTGER4	1.21e-04	159	71	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	NUDT11 PPFIA2 TRPC6 LPP	1.24e-04	160	71	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	NUDT11 PPFIA2 TRPC6 LPP	1.27e-04	161	71	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RC3H2 PPFIA4 PLXNB2 CEP55	1.30e-04	162	71	4	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.43e-04	166	71	4	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.43e-04	166	71	4	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARL5C SACS ADGRE3 FMNL1	1.47e-04	167	71	4	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	droplet-Tongue-TONGUE-1m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.47e-04	167	71	4	e85d97f8b0127663a3295db2b22b8488c0148455
ToppCell	droplet-Tongue-TONGUE-1m-Myeloid\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.47e-04	167	71	4	ac21c7112b592e30473e693a2bbee81ff0bb0160
ToppCell	droplet-Tongue-TONGUE-1m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.47e-04	167	71	4	a54e200789db14f41c9fc8d21cd7fa7cedde77ad
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C ITGA4 FMNL1 CEP55	1.50e-04	168	71	4	84977db9d71e59208727885320cc18d80d064380
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 ITGA4 FMNL1	1.50e-04	168	71	4	ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 ITGA4 FMNL1	1.50e-04	168	71	4	af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 VCAN ITGA4	1.50e-04	168	71	4	0ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 VCAN ITGA4	1.50e-04	168	71	4	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C VCAN ITGA4 FMNL1	1.53e-04	169	71	4	907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 NRXN2 PPFIA4 PTGER4	1.57e-04	170	71	4	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C ITGA4 PLXNB2 FMNL1	1.57e-04	170	71	4	4d28dc9eb572f43809619f923978cd7494853d43
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 NRXN2 PPFIA4 PTGER4	1.57e-04	170	71	4	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C ITGA4 PLXNB2 FMNL1	1.60e-04	171	71	4	ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C PPFIA4 PTGER4 FMNL1	1.60e-04	171	71	4	87cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NUDT11 FRYL LSM11 LGALS3BP	1.60e-04	171	71	4	6a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NUDT11 FRYL LSM11 LGALS3BP	1.60e-04	171	71	4	9be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NRXN2 PPFIA4 PTGER4	1.64e-04	172	71	4	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	facs-BAT-Fat-18m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 ITGA4 PLXNB2 FMNL1	1.64e-04	172	71	4	36fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	1.64e-04	172	71	4	66823536288c7009ce01b5177794a3e874e94570
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5C VCAN ITGA4 FMNL1	1.64e-04	172	71	4	f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NRXN2 PPFIA4 PTGER4	1.64e-04	172	71	4	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMN1 ITGA4 FMNL1 CEP55	1.64e-04	172	71	4	ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NUDT11 NRXN2 PPFIA4	1.68e-04	173	71	4	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NUDT11 NRXN2 PPFIA4	1.68e-04	173	71	4	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSC22D1 MISP CCDC158 JHY	1.72e-04	174	71	4	a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSC22D1 MISP CCDC158 JHY	1.72e-04	174	71	4	6cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSC22D1 MISP CCDC158 JHY	1.72e-04	174	71	4	4b8bc5568e36031c8ecf001bb646809038c23919
ToppCell	droplet-Marrow-nan-24m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 VCAN PLXNB2	1.79e-04	176	71	4	eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 NUDT11 NUDT10 LGALS3BP	1.79e-04	176	71	4	3027d34fd663c8a08544d469183dc45138916749
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL17A1 UGT2A3 NUDT10 LGALS3BP	1.83e-04	177	71	4	9e65b39fd797b6ce204b6480415810d1923acee5
ToppCell	droplet-Liver-LIVER-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C VCAN ITGA4 FMNL1	1.83e-04	177	71	4	12f804438add5e016b65f066e8363921ba28f919
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	RC3H2 TSC22D1 PPFIA2 MYH15	1.83e-04	177	71	4	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	droplet-Liver-LIVER-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C VCAN ITGA4 FMNL1	1.83e-04	177	71	4	3b6b6a6a13458c5ffb8df8873372efad9fda6eee
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA4 FMNL1 CCDC136 JHY	1.87e-04	178	71	4	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	Somatosensory_Cortex_(S1)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FMN1 LPP ITGA4 RFX3	1.91e-04	179	71	4	82348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCell	droplet-Tongue-nan-24m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARL5C PPFIA4 ITGA4 FMNL1	2.04e-04	182	71	4	0f06309318c064f0ebdb12a46226b90032290137
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	PPFIA2 LPP SLMAP MYH15	2.08e-04	183	71	4	818fd886e0188091310825f9145fa53328f2c979
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIA2 VCAN TRPC6 LPP	2.08e-04	183	71	4	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	FRYL ITGA4 SPEN EXOC4	2.17e-04	185	71	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	ADGRE3 SMG9 PLXNB2 ZNF697	2.21e-04	186	71	4	3314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PPFIA2 VCAN MUC16 MYH15	2.21e-04	186	71	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	FRYL ITGA4 SPEN EXOC4	2.21e-04	186	71	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CEP350 SETX LPP SLMAP	2.21e-04	186	71	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ZFAND3 LPP SPEN DYNC1H1	2.31e-04	188	71	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RC3H2 LUC7L3 VCAN TBCK	2.35e-04	189	71	4	160963355256f7c0f2138da80c90de478f5a9fe8
ToppCell	facs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 MTHFD1 OSBPL1A LGALS3BP	2.35e-04	189	71	4	533685a921a65d84107d8d33c43b4fffde019143
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TSC22D1 NUDT11 OSBPL1A NUDT10	2.35e-04	189	71	4	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	facs-Marrow-KLS-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 MTHFD1 OSBPL1A LGALS3BP	2.35e-04	189	71	4	dca56ab02bf0505f9a352ff907edaef30906d854
ToppCell	facs-Marrow-KLS-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 MTHFD1 OSBPL1A LGALS3BP	2.40e-04	190	71	4	a513c1e7df62c28128c932a68b252ee8f0255172
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 TRPC6 OSBPL1A LGALS3BP	2.40e-04	190	71	4	96a9756cad5468a12591021e6d661ed269b5b3d9
ToppCell	facs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 TRPC6 OSBPL1A LGALS3BP	2.40e-04	190	71	4	11f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCell	facs-Marrow-KLS-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 TRPC6 OSBPL1A LGALS3BP	2.40e-04	190	71	4	20f4f6fe09345878484086047061d6f900f9d476
ToppCell	hematopoetic_progenitors-CD34+_CLP\|World / Lineage and Cell class	TSC22D1 NRXN2 ITGA4 LGALS3BP	2.45e-04	191	71	4	32f2537c97c9984629d61c6f34a337f555146ad4
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR2 STAC2 COL17A1 FRYL	2.45e-04	191	71	4	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 TRPC6 OSBPL1A LGALS3BP	2.50e-04	192	71	4	959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 MTHFD1 OSBPL1A LGALS3BP	2.50e-04	192	71	4	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZFAND3 FMN1 LPP EXOC4	2.55e-04	193	71	4	779276e775cb2492e8dd36436295a536084a6415
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPC6 LPP SLMAP ITGA4	2.55e-04	193	71	4	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	ASK440-Epithelial-Secretory\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	FSIP2 TSC22D1 MISP COL17A1	2.55e-04	193	71	4	50e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	LUC7L3 VCAN TBCK RFX3	2.55e-04	193	71	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	TSC22D1 PPFIA2 VCAN EXOC4	2.55e-04	193	71	4	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW2 TRPC6 ITGA4 CEP55	2.60e-04	194	71	4	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STAC2 MISP FAM161A MUC16	2.60e-04	194	71	4	ea5b7727ffef6cb454c501979a51bc1d4108d0e4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN1 VCAN ITGA4 FMNL1	2.65e-04	195	71	4	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ITGA4 PTGER4 FMNL1 CEP55	2.65e-04	195	71	4	c75d04b15d9f95fe2b5650cd4a5a376776610000
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 FRYL MGA DYNC1H1	2.65e-04	195	71	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	VCAN OSBPL1A LGALS3BP CEP55	2.65e-04	195	71	4	578bbb06a5476c08fc3b351cc580c551dfe53ae4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 FRYL MGA DYNC1H1	2.65e-04	195	71	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	proximal-Hematologic-Interstitial_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RC3H2 NRXN2 VCAN NLRP8	2.70e-04	196	71	4	b6a858c43fef42cd724d56c8283e954bcb546106
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STAC2 COL17A1 PPFIA2 CCDC158	2.70e-04	196	71	4	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	proximal-3-Hematologic-Interstitial_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RC3H2 NRXN2 VCAN NLRP8	2.70e-04	196	71	4	d8c9cb86233470c3044865ad05ea202e294d80bf
ToppCell	proximal-Hematologic-Interstitial_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RC3H2 NRXN2 VCAN NLRP8	2.70e-04	196	71	4	9d4d8ffe9d30de7d1dc33d261bc2aaf4189ad86c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STAC2 COL17A1 PPFIA2 CCDC158	2.75e-04	197	71	4	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FMN1 VCAN ITGA4 FMNL1	2.75e-04	197	71	4	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSC22D1 TRPC6 LPP SLMAP	2.75e-04	197	71	4	1a6b2ca94a4634c24cd95481576c955b20000a5f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN1 VCAN ITGA4 FMNL1	2.75e-04	197	71	4	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FMN1 VCAN ITGA4 FMNL1	2.81e-04	198	71	4	ea34096bee852a7e996f097fa279381afa8f86ff
Computational	Genes upregulated in subsets of cells of a given type within various tumors	CEP350 SETX ITGA4 DYNC1H1	2.79e-05	49	39	4	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	LUC7L3 LPP SPEN DYNC1H1	3.02e-05	50	39	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Computational	Neighborhood of MAP4K4	CEP350 ZFAND3 TBCK FRYL DYNC1H1	3.67e-04	172	39	5	GCM_MAP4K4
Drug	diadenosine 5',5''''-P1,P6-hexaphosphate	NUDT11 NUDT10	9.59e-06	2	71	2	ctd:C070070
Drug	adenosine 5'-tetraphosphate	NUDT11 NUDT10	9.59e-06	2	71	2	ctd:C017991
Drug	adenosine 5'-pentaphosphate	NUDT11 NUDT10	9.59e-06	2	71	2	ctd:C048567
Disease	facial depth measurement	TRPC6 TRPM1	1.92e-04	9	69	2	EFO_0007857
Disease	Charcot-Marie-Tooth Disease	SETX MORC2	3.50e-04	12	69	2	C0007959
Disease	urate measurement, bone density	FSIP2 LUC7L3 PPFIA2 ADGRE3 TRPC6 LPP JHY	6.05e-04	619	69	7	EFO_0003923, EFO_0004531
Disease	cardioembolic stroke	NCOR2 PPFIA4 TRPC6 CCDC136	6.87e-04	170	69	4	EFO_1001976
Disease	susceptibility to scarlet fever measurement	PPFIA2 SEC24B FRYL	8.52e-04	79	69	3	EFO_0008409
Disease	nevus count, cutaneous melanoma	MIA3 FMN1 PLXNB2	1.28e-03	91	69	3	EFO_0000389, EFO_0004632
Disease	Disorder of eye	FAM161A VCAN TRPM1 BBS12	1.55e-03	212	69	4	C0015397

Protein segments in the cluster

Peptide	Gene	Start	Entry
ERIVTETVTTRLTSL	COL17A1	16	Q9UMD9
IDSTDRDRLLTTREE	ARL5C	91	A6NH57
DTLITLDTSRIITES	VCAN	1666	P13611
EDSDRETLRLLVDTS	BRICD5	131	Q6PL45
STTTLLEQLEETTRE	CEP55	96	Q53EZ4
TRSEELTRSEELTLS	BAG1	81	Q99933
SSTVRLLESLDLTSA	BBS12	51	Q6ZW61
RSEREDEVLLVSSSR	NUDT10	26	Q8NFP7
LISRSTDSTLRALET	RC3H2	506	Q9HBD1
TTERERLLTNLLSSD	FMN1	91	Q68DA7
DTILSERTRDVESLA	KASH5	306	Q8N6L0
FRTSSTLEIDTEELT	HECW2	386	Q9P2P5
TLEIDTEELTSTSSR	HECW2	391	Q9P2P5
SQSSDLLERERESVL	MISP	541	Q8IVT2
RTEISSSRTSISDLD	MUC16	5521	Q8WXI7
TTRLRETSTSEETSL	MUC16	7541	Q8WXI7
RDREREKSILTSTTT	NCOR2	1806	Q9Y618
LDRTSVSSLSEVEEV	ELOA2	356	Q8IYF1
EESRSELSGRTTRTD	LSM11	291	P83369
ILSRVESESQLSSER	JHY	596	Q6NUN7
ETRSTHTLDLSRELS	LGALS3BP	126	Q08380
ISDSISTERILDDSK	MGA	556	Q8IWI9
LTSTLIDRLEDLSED	NLRP8	291	Q86W28
STELRAEEIETRVTS	PPFIA4	596	O75335
TLERSVFSERTEESS	CARM1	131	Q86X55
TTDTLEIRIRTSSNE	FSIP2	5641	Q5CZC0
IIVSTRLLDRTDSRE	PLXNB2	181	O15031
RLESRISELTSELTD	MYO18A	1286	Q92614
EDTTSLRTLRISETS	PTGER4	426	P35408
TATTLSDVLSRLVET	FRYL	1841	O94915
ATTSRESADTLRLEL	NRXN2	771	Q9P2S2
EERRSSLDAEIDSLT	LPP	111	Q93052
KEERELLRSTTSTIE	LUC7L3	166	O95232
RSEREDEVLLVSSSR	NUDT11	26	Q96G61
SDSESERSLSRLEAV	OSBPL1A	481	Q9BXW6
LSVSTETLESELEAR	LRRC58	21	Q96CX6
SEESLRTSERKLRET	MORC2	976	Q9Y6X9
SVIRTLSTSDDVEDR	EXOC4	26	Q96A65
RETIESLSSSEESIT	CSN2	16	P05814
SLTESERSRGSLESI	CEP350	2151	Q5VT06
DVSSLSRAEEDLSIT	ITGA4	731	P13612
ESTQVLRELETSLRT	FMNL1	116	O95466
EDRAVESRTTDLLTD	DYNC1H1	1246	Q14204
DLESTVSQLRSELRE	CCDC158	321	Q5M9N0
LESSERTISDLTTSL	CCDC158	491	Q5M9N0
IREDSLSDSSRSVSE	FAM161A	131	Q3B820
ELDTLSSERARSFIT	SEC24B	1201	O95487
RLSISVIDSSDEATI	SACS	961	Q9NZJ4
TDTESELDLISRLSR	MTHFD1	761	P11586
SDTVDRLLTESNERL	PPFIA2	466	O75334
DISSLSTEELRQRVD	RUNDC1	236	Q96C34
TIRETTRVDAVSSLS	RTN3	811	O95197
LTISESSISDRLVTL	RSPRY1	261	Q96DX4
LVSDDETTRLVTSLE	MIA3	286	Q5JRA6
TITESSNLSEIESRL	RFX3	396	P48380
LSTRDVQESRELLES	RGPD2	246	P0DJD1
SSLDSEAKSRIEVTR	MYH15	1611	Q9Y2K3
ERERRDASEETSTSV	SMG9	46	Q9H0W8
IVSTRLLTDSSTDAL	SETX	741	Q7Z333
SSEILDVSLSRATDL	TSC22D1	151	Q15714
RRDTVETSSDSVIAE	SLX4IP	186	Q5VYV7
EISSTATTILRDVES	ADGRE3	156	Q9BY15
TSESDLETRKSLEVV	CCDC136	1006	Q96JN2
LDDTVSIASRSREVS	SPEN	91	Q96T58
TSTRDELLSARDEIL	SLMAP	571	Q14BN4
SESPTRSLSERDELT	STAC2	226	Q6ZMT1
ELSSELSTLLSSLSR	NUP188	1686	Q5SRE5
DRSSLLDDTTVTLSL	TBCK	371	Q8TEA7
SSSDERIRVTSERVE	TRPM1	1176	Q7Z4N2
LSESDSISRSLREDD	ZNF697	106	Q5TEC3
TSSLVTRLRVSTEES	ZNF502	111	Q8TBZ5
EDLLRALRTVITDSS	UGT2A3	421	Q6UWM9
RSTSLSIEEERFLDA	TRPC6	91	Q9Y210
LLENTERSEETSRSK	ZFAND3	136	Q9H8U3