Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSushi

SUSD3 SELL SELP PAMR1 APOH SEZ6

2.49e-05522106PF00084
DomainCCP

SUSD3 SELL SELP PAMR1 APOH SEZ6

3.10e-05542106SM00032
DomainSUSHI

SUSD3 SELL SELP PAMR1 APOH SEZ6

3.82e-05562106PS50923
DomainSushi_SCR_CCP_dom

SUSD3 SELL SELP PAMR1 APOH SEZ6

4.23e-05572106IPR000436
DomainRCC1

MYCBP2 RCC1 HERC2 HERC4

6.53e-05202104PF00415
DomainRCC1_1

MYCBP2 RCC1 HERC2 HERC4

8.00e-05212104PS00625
DomainRCC1_2

MYCBP2 RCC1 HERC2 HERC4

8.00e-05212104PS00626
DomainRCC1_3

MYCBP2 RCC1 HERC2 HERC4

8.00e-05212104PS50012
Domain-

MYCBP2 RCC1 HERC2 HERC4

9.69e-052221042.130.10.30
DomainReg_chr_condens

MYCBP2 RCC1 HERC2 HERC4

9.69e-05222104IPR000408
DomainRCC1/BLIP-II

MYCBP2 RCC1 HERC2 HERC4

1.16e-04232104IPR009091
DomainFISNA

NLRP12 NLRP3

1.26e-0422102SM01288
DomainKELK

CDC42BPA CDC42BPB

1.26e-0422102IPR031597
DomainNACHT-assoc

NLRP12 NLRP3

1.26e-0422102IPR029495
DomainFISNA

NLRP12 NLRP3

1.26e-0422102PF14484
DomainKELK

CDC42BPA CDC42BPB

1.26e-0422102PF15796
DomainZP_dom_CS

ZP2 ZP1 TGFBR3

1.59e-04102103IPR017977
DomainAgo_hook

TNRC6B TNRC6A

3.75e-0432102PF10427
DomainSelectin_superfamily

SELL SELP

3.75e-0432102IPR002396
DomainRequiem/DPF_N_dom

DPF1 DPF3

3.75e-0432102IPR025750
DomainTNRC6_PABC-bd

TNRC6B TNRC6A

3.75e-0432102IPR032226
DomainArgonaute_hook_dom

TNRC6B TNRC6A

3.75e-0432102IPR019486
DomainTNRC6-PABC_bdg

TNRC6B TNRC6A

3.75e-0432102PF16608
DomainRequiem_N

DPF1 DPF3

3.75e-0432102PF14051
DomainZP_2

ZP2 ZP1 TGFBR3

4.65e-04142103PS51034
DomainZP_1

ZP2 ZP1 TGFBR3

4.65e-04142103PS00682
DomainZP

ZP2 ZP1 TGFBR3

5.77e-04152103SM00241
DomainMyotonic_dystrophy_kinase_coil

CDC42BPA CDC42BPB

7.44e-0442102IPR014930
DomainMyotonic_dystrophy_kinase_coil

CDC42BPA CDC42BPB

7.44e-0442102PD011252
DomainDMPK_coil

CDC42BPA CDC42BPB

7.44e-0442102PF08826
DomainZP_dom

ZP2 ZP1 TGFBR3

8.48e-04172103IPR001507
DomainZona_pellucida

ZP2 ZP1 TGFBR3

8.48e-04172103PF00100
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KNTC1 MYO5A DOCK5 SBF1 PRRC2C NUP210 XRN1 HERC2 AP3D1 CDC42BPA ECPAS CDC42BPB

6.60e-092022181233005030
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO5A MYCBP2 ACOT7 KIF4A RCC1 URB2 DDB1 NUP205 POLR1F NF1 FBXL18 PELO AP2A2 SBF1 XRN1 ZNF638 HERC2 AP3D1 PLEKHG4 KIF21A UBR4 WDR59 SMG8 EIF2D SLC16A1 PA2G4

4.42e-0713532182629467282
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYCBP2 NUP205 PRRC2C AGL NUP210 PKHD1 ZNF638 CDC42BPA CDC42BPB SLC16A1

6.65e-072022181024639526
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

RASGRP4 TGIF2 NUP205 PTPN11 NF1 FBXL18 PELO OR4K1 XRN1 MTO1 HEATR3 TAFAZZIN LCMT1 SIN3B UBR4 DCLRE1B WDR59 PCED1B SMG8 SLC25A36 EIF2D ATAD1 SLC16A1 SLC25A28

3.59e-0613272182432694731
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

MYO5A AP2A2 NFATC3 AGL ZNF638 ABCC10 SDHC PLEKHG4 ST3GAL3 ZBTB44 RASGRP1 RNF220 NUDT1 VANGL1 EXD2 SLC25A19 HERC4 MYB SEZ6

6.78e-069252181928986522
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IFT140 NUP205 STOX2 SBF1 TNRC6A SDK2 CDC42BPA FLYWCH1 KIF21A E2F3 ECPAS HMGXB3 KAT6B HERC4

7.25e-065292181414621295
Pubmed

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.

MYO5A NF1 LRIG1 VANGL1

8.27e-0621218425340873
Pubmed

Genome wide molecular analysis of minimally differentiated acute myeloid leukemia.

JAK2 PTPN11 NF1

8.35e-067218319773259
Pubmed

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.

MYCBP2 HERC2 RGS12

8.35e-067218336700049
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYO5A MYCBP2 TNRC6B KIF4A DDB1 STOX2 NF1 AP2A2 SBF1 NFATC3 PRRC2C MTCL1 HERC2 SIN3B KIF21A UBR4 CDC42BPB FAM171A2 KIF4B

1.19e-059632181928671696
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYO5A MYCBP2 KIF4A URB2 DDB1 NUP205 NF1 SBF1 PRRC2C NUP210 XRN1 ZNF638 HERC2 UBR4 ECPAS

1.82e-056532181522586326
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ATP7B MYO5A MYCBP2 TNRC6B URB2 TYSND1 DDB1 AP2A2 NUP210 HERC2 HEATR3 ALG11 ECPAS WDR59 ATAD1 JRK

2.50e-057542181633060197
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MYCBP2 NEK4 POLR1F STOX2 NF1 SBF1 NFATC3 PRRC2C XRN1 MTCL1 CDC42BPA NCKIPSD WDR59 RGS12 FAM171A2 SLC16A1 ARHGEF10

3.44e-058612181736931259
Pubmed

Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

OR3A3 OR3A1 OR3A2

3.86e-051121838004088
Pubmed

Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.

MYO5A SELL IL1A

3.86e-051121831421760
Pubmed

TAM receptors and the regulation of erythropoiesis in mice.

AXL MERTK

3.91e-052218219211638
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

3.91e-052218236482480
Pubmed

Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.

AXL MERTK

3.91e-052218218247125
Pubmed

Increased Mer and Axl receptor tyrosine kinase expression on glomeruli in lupus nephritis.

AXL MERTK

3.91e-052218228127639
Pubmed

TRIM38 suppresses migration, invasion, metastasis, and proliferation in non-small cell lung cancer (NSCLC) via regulating the AMPK/NF-κB/NLRP3 pathway.

TRIM38 NLRP3

3.91e-052218237566200
Pubmed

Role of GW182 protein in the cell.

TNRC6B TNRC6A

3.91e-052218229791863
Pubmed

MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.

AXL MERTK

3.91e-052218223617806
Pubmed

The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages.

AXL MERTK

3.91e-052218235967387
Pubmed

Role of selectins in experimental Staphylococcus aureus-induced arthritis.

SELL SELP

3.91e-052218210898496
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

3.91e-052218230081192
Pubmed

The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding.

FADD NLRP3

3.91e-052218230804327
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

3.91e-052218231067151
Pubmed

Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.

CDC42BPA CDC42BPB

3.91e-052218210198171
Pubmed

Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson's disease.

ATP7B NLRP3

3.91e-052218233462188
Pubmed

Hypoxia inhibits JAK2V617F activation via suppression of SHP-2 function in myeloproliferative neoplasm cells.

JAK2 PTPN11

3.91e-052218224860972
Pubmed

Opposing Roles of Tyrosine Kinase Receptors Mer and Axl Determine Clinical Outcomes in Experimental Immune-Mediated Nephritis.

AXL MERTK

3.91e-052218227527599
Pubmed

Platelet, not endothelial, P-selectin expression contributes to generation of immunity in cutaneous contact hypersensitivity.

SELL SELP

3.91e-052218220056837
Pubmed

Bi-Allelic Mutations in NUP205 and NUP210 Are Associated With Abnormal Cardiac Left-Right Patterning.

NUP205 NUP210

3.91e-052218231306055
Pubmed

PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway.

PIK3CD NLRP3

3.91e-052218234162771
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

3.91e-052218210559369
Pubmed

Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection.

AXL MERTK

3.91e-052218236581764
Pubmed

Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation.

AXL MERTK

3.91e-052218228916522
Pubmed

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer.

AXL MERTK

3.91e-052218222890323
Pubmed

Rare mutations in NLRP3 and NLRP12 associated with familial cold autoinflammatory syndrome: two Chinese pedigrees.

NLRP12 NLRP3

3.91e-052218235852776
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

3.91e-052218221565503
Pubmed

Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells.

AXL MERTK

3.91e-052218221540291
Pubmed

Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.

AXL MERTK

3.91e-052218225904803
Pubmed

Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins.

SELL SELP

3.91e-052218212093896
Pubmed

L- and P-selectins collaborate to support leukocyte rolling in vivo when high-affinity P-selectin-P-selectin glycoprotein ligand-1 interaction is inhibited.

SELL SELP

3.91e-052218215743805
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

3.91e-05221827929562
Pubmed

Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.

CDC42BPA CDC42BPB

3.91e-052218218263588
Pubmed

Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer.

AXL MERTK

3.91e-052218223878224
Pubmed

PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.

RCC1 PRMT6

3.91e-052218233539787
Pubmed

Selectin-mediated adhesion in shear flow using micropatterned substrates: multiple-bond interactions govern the critical length for cell binding.

SELL SELP

3.91e-052218222627390
Pubmed

Syp associates with gp130 and Janus kinase 2 in response to interleukin-11 in 3T3-L1 mouse preadipocytes.

JAK2 PTPN11

3.91e-05221827559603
Pubmed

Downregulation of ClC-2 by JAK2.

JAK2 CLCN2

3.91e-052218222613974
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

3.91e-052218231486502
Pubmed

Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.

AXL MERTK

3.91e-052218230723115
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

3.91e-052218210773663
Pubmed

Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression.

JAK2 SELP

3.91e-052218230171023
Pubmed

Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer.

AXL MERTK

3.91e-052218232571802
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

3.91e-052218231616463
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

3.91e-052218228350061
Pubmed

Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity.

AXL MERTK

3.91e-052218233239426
Pubmed

Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.

SELL SELP

3.91e-052218211854515
Pubmed

Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance.

MYO5A RYR3

3.91e-052218227134178
Pubmed

Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.

AXL MERTK

3.91e-05221827784083
Pubmed

EBP1 is a novel E2F target gene regulated by transforming growth factor-β.

E2F3 PA2G4

3.91e-052218221085677
Pubmed

NF1 gene mutations represent the major molecular event underlying neurofibromatosis-Noonan syndrome.

PTPN11 NF1

3.91e-052218216380919
Pubmed

Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1.

FCAR CD79A

3.91e-05221828666916
Pubmed

Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction.

AXL MERTK

3.91e-052218225403570
Pubmed

T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation.

PTCRA PTPN11

3.91e-052218235983034
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

3.91e-052218224658398
Pubmed

Phosphorylation of SHP-2 regulates interactions between the endoplasmic reticulum and focal adhesions to restrict interleukin-1-induced Ca2+ signaling.

PTPN11 IL1A

3.91e-052218216905534
Pubmed

Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice.

AXL NLRP3

3.91e-052218227780404
Pubmed

Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK.

AXL MERTK

3.91e-052218228935638
Pubmed

Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas.

SELL SELP

3.91e-052218212975470
Pubmed

Novel mutations in ZP1 and ZP2 cause primary infertility due to empty follicle syndrome and abnormal zona pellucida.

ZP2 ZP1

3.91e-052218232829425
Pubmed

Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice.

AXL MERTK

3.91e-052218221918185
Pubmed

Independent NF1 and PTPN11 mutations in a family with neurofibromatosis-Noonan syndrome.

PTPN11 NF1

3.91e-052218219449407
Pubmed

Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.

AXL MERTK

3.91e-052218228251492
Pubmed

Cone-rod dystrophy associated with amelogenesis imperfecta in a child with neurofibromatosis type 1.

NF1 CNNM4

3.91e-052218221728811
Pubmed

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.

NLRP12 NLRP3

3.91e-052218238261657
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

3.91e-052218223500491
Pubmed

Differential regulation of lung homeostasis and silicosis by the TAM receptors MerTk and Axl.

AXL MERTK

3.91e-052218238774866
Pubmed

The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development.

RASGRP4 RASGRP1

3.91e-052218222262848
Pubmed

[The analysis of the influence of short term physical effort on selected endothelial function parameters and blood vessels stiffness features among young and healthy men].

SELL SELP

3.91e-052218225095634
Pubmed

Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model.

ATP7B HR

3.91e-052218222308360
Pubmed

Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.

NLRP12 NLRP3

3.91e-052218220861349
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

3.91e-05221829658142
Pubmed

TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice.

AXL MERTK

3.91e-052218234120143
Pubmed

Protective effects of fucoidan, a P- and L-selectin inhibitor, in murine acute pancreatitis.

SELL SELP

3.91e-052218224177139
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

MYCBP2 TNRC6B AP2A2 PRRC2C TNRC6A XRN1 ZNF638 MTO1 SLC25A36 MBNL2 EXD2 SLC25A19

3.95e-054622181231138677
Pubmed

Defining the membrane proteome of NK cells.

ATP7B MYO5A MYCBP2 KIF4A TYSND1 NUP205 NF1 PRRC2C NUP210 XRN1 HERC2 AP3D1 UBR4 ALG11 GTPBP1 ECPAS ATAD1 SLC16A1 PA2G4 SLC37A4

5.19e-0511682182019946888
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

KNTC1 ATP7B MYCBP2 TNRC6B KIF4A DDB1 NEK4 TNRC6A XRN1 ZNF638 WDR59 ATAD1 ARHGEF10 VANGL1 RSBN1L

6.75e-057332181534672954
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

SLCO2B1 DOCK5 NF1 CLCN2 VPS51 CDC42BPA CDC42BPB RGS12 FAM171A2 SLC16A1 VANGL1 EXD2 DCBLD2

6.98e-055692181330639242
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

NUP205 RPS6KC1 DOCK5 JAK2 AGL PKHD1 MTCL1 HEATR3 SIN3B KIF21A UBR4 BRME1 PCARE ECPAS ZBTB44

7.06e-057362181529676528
Pubmed

Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.

PTPN11 PRRC2C MYB

8.40e-0514218315747776
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DPF1 IFT140 ATP7B TNRC6B DDB1 PELO SH3TC1 TNRC6A XRN1 MTO1 VPS51 GPATCH2 SLC16A1 VANGL1 DPF3 SLC25A19 KAT6B RSBN1L TCTN2

8.66e-0511162181931753913
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

ACOT7 NUP205 PTPN11 C17orf75 AP2A2 SBF1 ALDH6A1 HEATR3 HDHD5 DUSP5 CDC42BPB CNNM4 EIF2D NUDT1 PA2G4 VANGL1 SLC25A19

8.96e-059312181727432908
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MYCBP2 NF1 PRRC2C RBM15B MTCL1 CPLANE1 DNAH9 SDK2 UBR4 ASXL3

1.03e-043612181026167880
Pubmed

Human transcription factor protein interaction networks.

DPF1 MYO5A TNRC6B DDB1 NUP205 NFATC3 PRRC2C TNRC6A XRN1 ZNF638 HERC2 SIN3B CDC42BPA UBR4 E2F3 GTPBP1 TDP2 SLC25A36 DPF3 ELF4 HAL MYB

1.03e-0414292182235140242
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ATP7B PTPN11 APEX2 SELENOO ALAS2 MTO1 ALDH6A1 TAFAZZIN SDHC SLC25A27 HDHD5 SLC25A36 ATAD1 NUDT1 EXD2 ETHE1 FAM222B SLC25A19 SLC25A28

1.09e-0411362181934800366
Pubmed

Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.

SELL SELP

1.17e-043218210500197
Pubmed

Microglia use TAM receptors to detect and engulf amyloid β plaques.

AXL MERTK

1.17e-043218233859405
InteractionLRRC31 interactions

KNTC1 MYO5A DOCK5 SBF1 PRRC2C NUP210 XRN1 HERC2 AP3D1 CDC42BPA ECPAS CDC42BPB

1.39e-0620520612int:LRRC31
InteractionOPALIN interactions

KNTC1 AXL URB2 ACVR1 NUP205 DOCK5 NF1 SBF1 VPS51 ECPAS FAM171A2 SLC25A19

1.71e-0620920612int:OPALIN
Cytoband2q23-q24

ACVR1 PLA2R1

2.24e-05221822q23-q24
Cytoband8p21.2

DOCK5 ADAMDEC1 HR

2.25e-042521838p21.2
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SUSD3 SELL SELP PAMR1 APOH SEZ6

6.73e-065714761179
GeneFamilyOlfactory receptors, family 3

OR3A3 OR3A1 OR3A2

1.03e-0561473150
GeneFamilyCD molecules|Selectins|Sushi domain containing|C-type lectin domain containing

SELL SELP

1.96e-0431472945
GeneFamilyZona pellucida glycoproteins

ZP2 ZP1

3.90e-04414728
GeneFamilyNLR family

NLRP12 NLRC3 NLRP3

1.06e-03251473666
GeneFamilyZinc fingers GRF-type|Topoisomerases

ZGRF1 APEX2

1.34e-0371472135
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NLRP12 ATP8B4 JAML DOCK5 SH3TC1 PIK3CD MERTK HEATR3 E2F3 NLRP3

5.60e-0820021710881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP8B4 MYO5A SLCO2B1 AP2A2 SH3TC1 MERTK HEATR3 E2F3 NLRP3

4.92e-071942179663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

NLRP12 ATP8B4 JAML DOCK5 SH3TC1 PIK3CD MERTK E2F3 NLRP3

5.36e-071962179cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 ATP8B4 SLCO2B1 JAML ADAMDEC1 MERTK DCLRE1B NLRP3 KCNH4

5.83e-0719821790b928a829844f49f4d47e88908af192cb919011f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

SLC16A12 JAK2 CLCN2 SH3TC1 NCKIPSD CNNM4 EIF2D SLC41A1 SLC25A19

6.34e-072002179e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTCRA JAML ARL5C MTCL1 SELL SDK2 WNT6 CBFA2T3

1.77e-061682178d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP8B4 PTCRA PIK3CD NUP210 SELL CBFA2T3 CD79A MYB

4.58e-06191217847f20686001f945bc31d5a0b974958e4009edb34
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RASGRP4 JAML FCAR SELL ADGRG3 NLRP3 HAL IL1A

4.94e-061932178b044fca95f519ff2ceb378afe40a95911931a29e
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYCBP2 KIF4A NUP210 XRN1 MTCL1 NLRC3 RASGRP1 KAT6B

5.33e-06195217883c125223e7ca0f08a31414b3a16347912564765
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RASGRP4 JAML FCAR PIK3CD SELL ADGRG3 APOH HAL

5.75e-061972178d2b2eaa6f7294ff56b84a69c8727c7e0f9fd0466
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 ATP8B4 MYO5A SLCO2B1 JAML SH3TC1 MERTK NLRP3

6.19e-061992178f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 DNAH9 NLRC3 RSPH10B DNAI2 CFAP46 MYB CDHR4

6.42e-06200217873ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 NEK4 AP2A2 SH3TC1 MERTK NLRP3 RNF220 IL1A

6.42e-062002178f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCellMS-CD4-CD8_2|MS / Condition, Cell_class and T cell subcluster

PELO ZNF541 SELL OR3A2 ZP1 CNNM4 PLA2R1

8.66e-06149217708fb6be5599c5988890c851ce5ac6781c319948e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAML ARL5C NFATC3 SMG8 IGHA2 CD79A

1.20e-051042176b6208db091c802f32fa64b2ef6701df1c0e9ad8b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAML ARL5C NFATC3 SMG8 IGHA2 CD79A

1.20e-051042176793cc94735f4339bb189d288972a90b38a8fa850
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PTCRA FCAR SELP AQP10 ADGRG3 NLRP3 IL1A

1.38e-05160217708696d93ff42a1beca23c70ab3e0d082cfff4aa7
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 GPR82 JAML NUP210 ALAS2 ILDR1 MYB

1.43e-0516121777e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC16A12 NUP205 ARL5C DNAH9 KIF21A SMG8 LRIG1

1.61e-051642177d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCellfacs-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGRF1 KIF4A RYR3 BRME1 PCED1B RASGRP1 ELF4

1.68e-051652177ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 JAML DOCK5 SELL WNT6 TGFBR3 DPF3

1.68e-051652177ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

ATP8B4 MYO5A SLCO2B1 AP2A2 ADAMDEC1 OR3A3 MERTK

1.75e-051662177be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN2 ALAS2 SLC16A1 VANGL1 DPF3 ACKR1 HR

1.89e-05168217717fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN2 ALAS2 SLC16A1 VANGL1 DPF3 ACKR1 HR

1.89e-051682177a61b39884851384cffd430079040546d125b2b40
ToppCellCOVID-19_Severe-Treg|COVID-19_Severe / disease group, cell group and cell class

GPR82 PCED1B RASGRP1 LRIG1 ADAMTS7 SLC16A1 CDHR4

2.04e-051702177d61269a51283125835884c4aa50623756c4fdda2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTCRA JAML ARL5C SELL SDK2 DUSP5 CBFA2T3

2.11e-05171217739c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCellCOVID-19-lung-RBC|lung / Disease (COVID-19 only), tissue and cell type

PTCRA RYR3 ALAS2 SELP AQP10 CBFA2T3 DPF3

2.11e-0517121770e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 NLRP12 JAML ALAS2 SELL ADGRG3 HAL

2.11e-051712177ef9397cec7f5c217d34583f26270af7ed7fbcebf
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARL5C POLR1F PIK3CD APOH RASGRP1 CD79A MYB

2.20e-05172217776c06a968d3333441eed103abef1e636a1c3e7a1
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 NLRP12 FCAR SELL ADGRG3 NLRP3 HAL

2.20e-051722177cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 ATP8B4 JAML ADAMDEC1 PIK3CD NLRP3 MYB

2.20e-051722177f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF4A ZIK1 SELP DUSP5 ASTE1 E2F3 SLC16A1

2.20e-051722177ebeda7ef181cac0109be750a98e7589c615d2724
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 GPR82 JAML DUSP5 NCKIPSD CBFA2T3 HAL

2.54e-0517621777b5e50eb144bf43ca0cf354a466eb58b976a79f1
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B4 JAML NLRC3 ADGRG3 OR3A2 DPF3 ANKRD36

2.74e-0517821770b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCellASK452-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

PTPN11 DNAH9 CDC42BPA DUSP5 GPATCH2 IGHA2 CD79A

2.84e-051792177c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCellmoderate-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTCRA ARL5C NUP210 SDK2 DUSP5 CBFA2T3 MYB

2.94e-0518021771d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

URB2 PRSS36 SBF1 SELENOO HEATR3 FEZ2 ARHGEF10

2.94e-0518021777368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PTCRA FCAR ALAS2 SELL SELP AQP10 CBFA2T3

3.15e-051822177e5e16abf4d3bd5a97e7c573b99f7a3d9a5add120
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 SUSD3 KIF4A JAML JAK2 PIK3CD NUP210

3.26e-051832177062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 JAML SH3TC1 PIK3CD NUP210 HDHD5 DUSP5

3.50e-051852177969248b63d4ce335f223528de756bcddffadbd77
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 ACOT7 KIF4A RCC1 NUP210 CD79A MYB

3.75e-051872177e53471c3e146a6f54788d81ecc469aba55b051bb
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AXL FBXL18 LRRN2 PAMR1 THSD7B VANGL1 ACKR1

3.75e-051872177fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 ACOT7 KIF4A RCC1 NUP210 CD79A MYB

3.75e-0518721773d7d51fbadb20dc884d0b3c0d61b80f022b19d09
ToppCellLPS-IL1RA+antiTNF-Myeloid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLRP12 JAML FCAR SELL LILRA3 NLRP3 IL1A

3.75e-0518721774e0bbef6ba0d1b3e1f8d900d4a9dbd41f09a7bc5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

GALK2 MYCBP2 RYR3 LRRN2 ABCC10 CBFA2T3 MYB

4.01e-0518921773717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP8B4 MYO5A SLCO2B1 PRSS36 AP2A2 MERTK NLRP3

4.14e-0519021772d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

ATP8B4 MYO5A SLCO2B1 JAML AP2A2 PIK3CD MERTK

4.29e-051912177e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SUSD3 PIK3CD NUP210 NLRC3 SELL PCED1B RASGRP1

4.43e-05192217792f141d5ac462f652f405efa73ac6ef751f40ea3
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NLRP12 FCAR PIK3CD SELL ADGRG3 HAL MYB

4.43e-0519221770ba5729a890bfba5db567cd0eec7924cd1991ac3
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NLRP12 JAML FCAR SELL ADGRG3 NLRP3 IL1A

4.43e-051922177d44f46352bac414b45cc749f7cbdc3a159bd7ae8
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

ATP8B4 MYO5A SLCO2B1 AP2A2 SH3TC1 MERTK NLRP3

4.58e-051932177a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RSPH10B2 CPLANE1 DNAH9 SLC25A36 LRIG1 CFAP46 CDHR4

4.58e-051932177ea345d34440b25f65358a53dc72831998d1c3620
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

SUSD3 JAML SELL SDK2 PCED1B CD79A MYB

4.58e-051932177627d345baf1940218c61907305705298e473dbab
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMC6 JAML PIK3CD NUP210 NLRC3 SELL RASGRP1

4.58e-051932177326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NLRP12 ATP8B4 FCAR SELL ADGRG3 NLRP3 HAL

4.58e-051932177888b11d7d66970931d1c33bea714659ca3cfe149
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

ATP8B4 MYO5A SLCO2B1 AP2A2 SH3TC1 MERTK NLRP3

4.58e-0519321775fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDB1 NFATC3 PRRC2C RBM15B RASGRP1 SLC16A1 MYB

4.73e-051942177f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 AXL GPR82 JAML AP2A2 SH3TC1 MERTK

4.73e-0519421777c7091de47359760003e910cfbe63db5c99410d6
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDB1 NFATC3 PRRC2C RBM15B RASGRP1 SLC16A1 MYB

4.73e-051942177cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDB1 NFATC3 PRRC2C RBM15B RASGRP1 SLC16A1 MYB

4.73e-05194217766c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 MYO5A SLCO2B1 AXL AP2A2 MERTK NLRP3

4.73e-051942177c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNRC6B ANKRD36C PRRC2C RASGRP1 MBNL2 CD79A ANKRD36

4.89e-051952177ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 MYO5A SLCO2B1 PIK3CD MERTK CBFA2T3 NLRP3

4.89e-05195217734a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 MYO5A SLCO2B1 AXL ARL5C MERTK NLRP3

5.05e-051962177cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellCOVID-19-COVID-19_Convalescent-Others-HSPC|COVID-19_Convalescent / Disease, condition lineage and cell class

ATP7B AQP10 CDC42BPA CBFA2T3 EXD2 DCBLD2 MYB

5.21e-051972177c1033a1a8b8b5c8569130aa9405a6e8e65ef7bd0
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B4 MYO5A SLCO2B1 AXL JAML SH3TC1 MERTK

5.21e-05197217710190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

STOX2 SCN1A DNAH9 AQP10 TGFBR3 ZDHHC11

5.26e-051352176cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 DNAH9 RSPH10B DNAI2 CFAP46 MYB CDHR4

5.38e-051982177f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellBiopsy_IPF-Immune-pDCs|Biopsy_IPF / Sample group, Lineage and Cell type

PTCRA JAML ARL5C SELL SDK2 DUSP5 CBFA2T3

5.38e-051982177aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 MYO5A SLCO2B1 AP2A2 SH3TC1 MERTK NLRP3

5.38e-051982177c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellSepsis-ICU-SEP-Myeloid-pDC|ICU-SEP / Disease, condition lineage and cell class

PTCRA AXL ACOT7 OR3A3 SDK2 CBFA2T3 MYB

5.38e-051982177fe8a68bff8c1b9566eee4bfcab564f206a20ae7b
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

NLRP12 ATP8B4 JAML DOCK5 SH3TC1 PIK3CD NLRP3

5.38e-051982177d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTCRA NUP210 ALAS2 DPF3 DNAI2 MYB

5.48e-051362176a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 SLCO2B1 JAML FCAR SH3TC1 E2F3 NLRP3

5.55e-0519921771413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KNTC1 NUP210 MERTK DUSP5 CBFA2T3 IGHA2 CD79A

5.55e-05199217758242d78517c05fa367a7c6edac57ef79107453c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_activated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 URB2 ADAMDEC1 DUSP5 VANGL1 ELF4 MYB

5.55e-0519921773b2bd3caf4d189a1726a737b0121860b265eec04
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-NK_CD56bright|Influenza_Severe / Disease, condition lineage and cell class

POLR1F PLEKHG4 ST3GAL3 TGFBR3 RASGRP1 ARHGEF10 VANGL1

5.55e-051992177784e7e7ede2baa28ede600834813e6de2240bfdf
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAML PIK3CD NUP210 NLRC3 SELL PCED1B RASGRP1

5.55e-0519921776150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 ATP8B4 SLCO2B1 RYR3 MTCL1 CBFA2T3 ADAMTS7

5.73e-0520021779156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 MYO5A SLCO2B1 AP2A2 SH3TC1 MERTK NLRP3

5.73e-052002177179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 DNAH9 NLRC3 DNAI2 CFAP46 MYB CDHR4

5.73e-052002177af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 NLRP12 ATP8B4 JAML FCAR SH3TC1 NLRP3

5.73e-0520021775432bdf495431cd26f6e4cd585100f3652588913
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 ATP8B4 SLCO2B1 JAML FCAR MERTK NLRP3

5.73e-05200217748ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ATP8B4 SLCO2B1 AXL SUSD3 JAML ADAMDEC1 SLC25A19

5.73e-052002177e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 ATP8B4 SLCO2B1 RYR3 MTCL1 CBFA2T3 ADAMTS7

5.73e-052002177566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Monocytic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 JAML POLR1F FCAR SELL NLRP3 IL1A

5.73e-0520021771003f0f417b015f0fe8ff71dd47449de22214d62
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP12 ATP8B4 JAML FCAR SH3TC1 PIK3CD NLRP3

5.73e-052002177b4277b6faa69f20974696c7c422311f5c89e3663
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARL5C ALDH6A1 NCKIPSD SMG8 IGHA2 CD79A

6.97e-051422176199a0a1024b6cc446f5ca1f277846a2bdb227a9f
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTCRA GCK SELL LILRA3 CBFA2T3 CD79A

7.82e-051452176bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUSD3 ARL5C DUSP5 RASGRP1 CD79A MYB

8.76e-051482176b78dac56b333bf901136ccafb0999f345e978f51
ToppCell368C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 KIF4A PRSS36 ALAS2 ADGRG3 CDC42BPA

9.43e-05150217617b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCellPND01-Immune-Immune_Myeloid-DC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR82 SUSD3 JAML SH3TC1 DCLRE1B SLC25A19

1.01e-041522176c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR82 SUSD3 JAML SH3TC1 DCLRE1B SLC25A19

1.01e-041522176c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR82 SUSD3 JAML SH3TC1 DCLRE1B SLC25A19

1.01e-041522176cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALAS2 SELL ADGRG3 NLRP3 CNNM4 IL1A

1.05e-041532176489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellControl-Myeloid-Neutrophils-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLRP12 JAML DOCK5 FCAR SELL LILRA3

1.05e-041532176e3630f2b10f33092a3b6a63dba3a39fbdecbc7bd
ToppCellControl-Myeloid-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLRP12 JAML DOCK5 FCAR SELL LILRA3

1.05e-041532176c33d63b2d1a220bc428e776b157b23faa43ea8ca
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5A GPR82 JAML ST3GAL3 CBFA2T3 RASGRP1

1.09e-041542176c663e9834be0b45389a862dc3c13a1f988a3e5ee
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACVR1 SDK2 EXD2 JRK CD79A TCTN2

1.17e-0415621767ece590fd8f29382e349dd0e5e016d2926aeb518
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

DNAH9 RSPH10B KIF21A ANKRD36 CFAP46 CDHR4

1.17e-04156217610d191e29b16cae8238e8df6c0ff38882253f34e
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

RCC1 JAK2 NUP210 ASTE1 E2F3 CBFA2T3 ECPAS RASGRP1 ELF4 KAT6B MYB

1.25e-06184211116939_DN
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

IFT140 GALK2 URB2 JAK2 ALDH6A1 DUSP5 GTPBP1 CBFA2T3 RASGRP1 SLC16A1 MYB

1.62e-06189211116997_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

IFT140 RCC1 JAK2 NUP210 E2F3 CBFA2T3 ECPAS RASGRP1 KAT6B MYB

6.32e-06177211107550_DN
Drugscriptaid; Down 200; 10uM; MCF7; HT_HG-U133A

TGIF2 RCC1 JAK2 E2F3 CBFA2T3 RASGRP1 ELF4 KAT6B MYB CYB561

6.98e-06179211106901_DN
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A

RCC1 JAK2 AP2A2 NUP210 GTPBP1 CBFA2T3 RASGRP1 SLC16A1 SLC25A28 MYB

9.33e-06185211106965_DN
Drugstearyl sulfate

PTPN11 SELL SELP

1.54e-0562113CID000008912
DrugSulfadoxine [2447-57-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A

IFT140 NF1 AP2A2 HEATR3 CDC42BPA NCKIPSD SLC25A36 GSTCD HERC4 CYB561

1.54e-05196211103547_DN
DrugVincamine [1617-90-9]; Down 200; 11.2uM; HL60; HT_HG-U133A

TNRC6B AP2A2 NFATC3 DUSP5 WDR59 FAM222B GSTCD KAT6B TCTN2 CYB561

1.54e-05196211102367_DN
Drug1-phenylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A

MYCBP2 TNRC6B EXOC6B MTO1 MERTK AP3D1 ATG10 KCNH4 CD79A ELF4

1.61e-051972111022_DN
DrugN-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; PC3; HT_HG-U133A

POLR1F NF1 FCAR SH3TC1 ALDH6A1 ATG10 POU1F1 RGS12 ARHGEF10 DNAI2

1.61e-05197211104622_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A

TMC6 RCC1 NF1 AP2A2 SBF1 NUP210 TAFAZZIN RGS12 ZBTB44 LRIG1

1.61e-05197211103277_DN
DrugNatamycin [7681-93-8]; Down 200; 6uM; HL60; HT_HG-U133A

GALK2 RCC1 NFATC3 AP3D1 TAFAZZIN DUSP5 NLRP3 ARHGEF10 GSTCD CYB561

1.76e-05199211106126_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

RBM15B E2F3 CBFA2T3 ECPAS RASGRP1 ELF4 KAT6B MYB CYB561

3.09e-0517021197043_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

RCC1 NUP210 CBFA2T3 ECPAS RASGRP1 ELF4 KAT6B MYB CYB561

3.71e-0517421191659_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

RCC1 JAK2 NUP210 E2F3 CBFA2T3 ECPAS RASGRP1 KAT6B MYB

3.88e-0517521196891_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NUP210 E2F3 CBFA2T3 ECPAS RASGRP1 RNF220 ELF4 KAT6B MYB

4.06e-0517621196932_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

JAK2 NUP210 E2F3 CBFA2T3 ECPAS RASGRP1 ELF4 KAT6B MYB

4.06e-051762119981_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A

TGIF2 ATP8B4 SH3TC1 PIK3CD NUP210 CBFA2T3 ELF4 KAT6B MYB

4.43e-0517821196193_DN
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

URB2 JAK2 NF1 NUP210 CBFA2T3 RASGRP1 LRIG1 KAT6B MYB

4.84e-0518021191076_DN
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ACOT7 CES2 JAK2 NF1 NCKIPSD CBFA2T3 RASGRP1 KAT6B MYB

5.27e-0518221191043_DN
Diseasediastolic blood pressure, systolic blood pressure

ATP8B4 AXL FADD TNRC6B GCK DOCK5 POLR1F LNX1 GSX2 APOH CBFA2T3 RGS12 ZBTB44 RASGRP1 RNF220 LRIG1 DPF3 FAM222B

1.45e-0667020818EFO_0006335, EFO_0006336
Diseaseessential thrombocythemia (implicated_via_orthology)

JAK2 MYB

4.95e-0522082DOID:2224 (implicated_via_orthology)
DiseaseOOCYTE MATURATION DEFECT 1

ZP2 ZP1

1.48e-0432082C4014291
DiseaseOOCYTE MATURATION DEFECT 3

ZP2 ZP1

1.48e-0432082C4540205
Diseaseobsolete aging

ATP8B4 OR3A3 SELP SIN3B POU1F1 ST3GAL3 THSD7B SP6 ACKR1

1.74e-042792089GO_0007568
DiseaseEpilepsy, Atonic

SCN1A JRK

2.94e-0442082C0086236
DiseaseJUVENILE MYELOMONOCYTIC LEUKEMIA

PTPN11 NF1

2.94e-0442082607785
DiseaseEpilepsy, Tonic

SCN1A JRK

2.94e-0442082C0086241
DiseaseGeneralized convulsive epilepsy

SCN1A JRK

2.94e-0442082C0311334
DiseaseSymptomatic Generalized Epilepsy

SCN1A JRK

2.94e-0442082C0270854
DiseaseGeneralized Nonconvulsive Seizure Disorder

SCN1A JRK

2.94e-0442082C0017332
DiseaseJuvenile myelomonocytic leukemia

PTPN11 NF1

2.94e-0442082cv:C0349639
DiseaseFamilial cold autoinflammatory syndrome

NLRP12 NLRP3

2.94e-0442082cv:C0343068
DiseaseEpilepsy, Akinetic

SCN1A JRK

2.94e-0442082C0347869
Diseasesensorineural hearing loss (implicated_via_orthology)

LNX1 DNAH9 DNAI2

3.08e-04192083DOID:10003 (implicated_via_orthology)
Diseaseenergy expenditure measurement

GPATCH2 THSD7B MBNL2

3.60e-04202083EFO_0008005
Diseaseantibody measurement

LRRN2 ALG11 LRIG1 ASXL3

3.96e-04492084EFO_0004556
Diseaseprotein fam107a measurement

NLRP12 APOH

4.88e-0452082EFO_0020673
Diseasejuvenile myelomonocytic leukemia (implicated_via_orthology)

PTPN11 NF1

4.88e-0452082DOID:0050458 (implicated_via_orthology)
DiseaseSchwannomatosis, Plexiform

AXL NF1

4.88e-0452082C0751374
DiseaseNeurodevelopmental Disorders

TNRC6B PTPN11 SCN1A CDC42BPB ASXL3

5.21e-04932085C1535926
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

NF1 MERTK SDHC

5.51e-04232083C1708353
DiseaseNoonan Syndrome

PTPN11 NF1 KAT6B

6.26e-04242083C0028326
DiseaseCerebral Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0750935
DiseaseIntracranial Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0750936
DiseaseAstrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0004114
DiseaseGrade I Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C1704230
DiseaseSubependymal Giant Cell Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0205768
DiseaseMixed oligoastrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0547065
DiseasePilocytic Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0334583
DiseaseJuvenile Pilocytic Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0280783
DiseaseDiffuse Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0280785
DiseaseChildhood Cerebral Astrocytoma

ACVR1 PTPN11 NF1

7.08e-04252083C0338070
Diseasebeta-hydroxybutyric acid measurement

MERTK THSD7B

7.28e-0462082EFO_0010465
Diseaseplastin-2 measurement

NLRP12 APOH

7.28e-0462082EFO_0801885
DiseaseEpilepsy, Generalized

SCN1A JRK

7.28e-0462082C0014548
DiseaseNeurilemmoma

AXL NF1

7.28e-0462082C0027809
Diseasemyelofibrosis (implicated_via_orthology)

JAK2 MYB

7.28e-0462082DOID:4971 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

ACVR1 PTPN11 NF1

7.96e-04262083C0334581
DiseaseProtoplasmic astrocytoma

ACVR1 PTPN11 NF1

7.96e-04262083C0334580
DiseaseFibrillary Astrocytoma

ACVR1 PTPN11 NF1

7.96e-04262083C0334582
DiseaseAnaplastic astrocytoma

ACVR1 PTPN11 NF1

8.91e-04272083C0334579
Diseasecognitive function measurement, self reported educational attainment

MYCBP2 NEK4 CLCN2 TNRC6A PKHD1 ZNF638 ST3GAL3 THSD7B EXD2

9.92e-043552089EFO_0004784, EFO_0008354
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

PTPN11 NF1

1.01e-0372082DOID:0050458 (is_implicated_in)
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

TNRC6A PKHD1 E2F3 PRMT6 LRIG1 FEZ2 SP6 SLC37A4 HR

1.18e-033642089EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A TNRC6A

1.35e-0382082C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A TNRC6A

1.35e-0382082C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A TNRC6A

1.35e-0382082C0338479
DiseaseFamilial hyperinsulinism

GCK SLC16A1

1.35e-0382082cv:C3888018
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A TNRC6A

1.35e-0382082C0751120
DiseaseJuvenile Myoclonic Epilepsy

CLCN2 JRK

1.35e-0382082C0270853
DiseaseMyoclonic Encephalopathy

SCN1A TNRC6A

1.35e-0382082C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A TNRC6A

1.35e-0382082C0393703
DiseaseMalignant Glioma

ACVR1 NF1 CLCN2 MYB

1.53e-03702084C0555198
Diseasemixed gliomas

ACVR1 NF1 CLCN2 MYB

1.53e-03702084C0259783
DiseaseMyoclonic Epilepsy

SCN1A TNRC6A

1.72e-0392082C0014550
Diseaseliver cancer (is_marker_for)

SLCO2B1 JAK2

1.72e-0392082DOID:3571 (is_marker_for)
DiseaseKunitz-type protease inhibitor 2 measurement

DPF1 RASGRP4

2.14e-03102082EFO_0008200
Diseasethrombosis (implicated_via_orthology)

JAK2 APOH

2.14e-03102082DOID:0060903 (implicated_via_orthology)
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A TNRC6A

2.14e-03102082C0917800
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPA CDC42BPB

2.61e-03112082DOID:0060669 (implicated_via_orthology)
DiseaseMyoclonic Astatic Epilepsy

SCN1A TNRC6A

2.61e-03112082C0393702
Diseasemean arterial pressure

POLR1F PTPN11 TNRC6A PKHD1 MERTK LNX1 ABCC10 THSD7B SEZ6 CYB561

3.01e-0349920810EFO_0006340
Diseasetriacylglycerol 58:12 measurement

LNX1 E2F3

3.12e-03122082EFO_0010439
DiseaseThromboembolism

JAK2 MERTK

3.12e-03122082C0040038
Diseaseobsolete_red blood cell distribution width

TMC6 PRSS36 DOCK5 PRRC2C NUP210 ALAS2 ALDH6A1 TRIM38 HEATR3 AQP10 ALG11 CBFA2T3 NLRP3 PRMT6 LRIG1 DPF3 FAM222B WDSUB1 MYB

3.29e-03134720819EFO_0005192
Diseaseserum albumin measurement

POLR1F PTPN11 LNX1 E2F3 APOH RGS12 NLRP3 IGHA2 SLC37A4 RSBN1L CDHR4

3.37e-0359220811EFO_0004535
DiseaseGlioma

ACVR1 NF1 CLCN2 MYB

3.38e-03872084C0017638
Diseaseoptic disc size measurement

SELP CDC42BPA GSX2 ARHGEF10 VANGL1 JRK

3.43e-032052086EFO_0004832
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A TNRC6A

3.66e-03132082C0751122
DiseaseDiverticular Bleeding

FADD GTPBP1

3.66e-03132082C4505353
DiseaseDiverticular Diseases

FADD GTPBP1

3.66e-03132082C4317009
Diseaseleukemia (is_implicated_in)

FADD JAK2

3.66e-03132082DOID:1240 (is_implicated_in)
Diseaseuric acid measurement

TMC6 ACVR1 SELENOO VPS51 CDC42BPA GPATCH2 LRIG1 DPF3 ILDR1 SLC41A1 HERC4

4.21e-0361020811EFO_0004761
Diseaseglycerate measurement

RYR3 THSD7B

4.89e-03152082EFO_0021029
DiseaseRASopathy

PTPN11 NF1

4.89e-03152082cv:C5555857
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

PTPN11 PELO E2F3 APOH RGS12 SP6

5.04e-032222086EFO_0008317, EFO_0020943
Diseasemean corpuscular hemoglobin concentration

KNTC1 IFT140 ATP7B AXL TMC6 TNRC6B URB2 NEK4 ZNF638 ALAS2 HEATR3 ABCC10 FAM222B KIF4B SLC25A28 MYB

5.35e-03110520816EFO_0004528
DiseaseInherited oocyte maturation defect

ZP2 ZP1

5.56e-03162082cv:CN238505
DiseaseSquamous cell carcinoma of the head and neck

ATP7B MERTK IL1A

5.92e-03522083C1168401
DiseaseGlycogen storage disease

AGL SLC37A4

6.27e-03172082cv:C0017919
Diseaseulcerative colitis (is_implicated_in)

JAK2 SELL

6.27e-03172082DOID:8577 (is_implicated_in)
Diseaseleukemia

JAK2 PTPN11 NF1

6.92e-03552083C0023418
DiseaseDiffuse Large B-Cell Lymphoma

JAK2 PIK3CD CD79A

6.92e-03552083C0079744
DiseaseHOMA-B

GCK TGFBR3 ARHGEF10

6.92e-03552083EFO_0004469
Diseaseautoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease

PRSS36 SLC25A27

7.02e-03182082EFO_0003779, EFO_0004237, EFO_0006812

Protein segments in the cluster

PeptideGeneStartEntry
ESILQHLAFCITNGM

VANGL1

421

Q8TAA9
SLNCSQYHSMSGPLI

URB2

621

Q14146
DFLSPMCIGEVAHVS

ACOT7

111

O00154
ECMAAGTIILAHNSG

ALG11

406

Q2TAA5
VQLSLHTKVGMHCSG

BPIFB3

111

P59826
GSCTHQMGQIAIVSF

ARHGEF10

926

O15013
CVPASMTLLFQESGH

EIF2D

386

P41214
MDVHVFCTDSIQGTP

NUDT1

81

P36639
PQHAMFGNDTITCTT

APOH

176

P02749
FLTNEVVHMCPTIGS

ARL5C

36

A6NH57
MACGVTGSVSVALHP

COPS6

31

Q7L5N1
MLSGVTGQSHICTSA

C2orf78

106

A6NCI8
ASCVHSIEGMISQLE

ATP7B

371

P35670
LPIMELSQELFHSGC

GJA10

486

Q969M2
HPSCLQFTVNMTAAV

DPF1

301

Q92782
AMVHCGSIRQTATIL

GTPBP1

511

O00178
FNTLMAVIGGLCHSS

RASGRP1

291

O95267
CIADLGLAVMHSQST

ACVR1

351

Q04771
VSGAHLNPAFSLAMC

AQP10

76

Q96PS8
HSGDPVMLVTLCNTL

CFAP46

776

Q8IYW2
MGNCLHRAELSPSTE

ACKR1

1

Q16570
HILTRISQAGCGVSM

ADGRG3

266

Q86Y34
RTALHLACATGQPEM

ANKRD36

66

A6QL64
LALCHTVMSEENSAG

ATP8B4

471

Q8TF62
ASTHGQTCLPMEEAF

ATG10

61

Q9H0Y0
SLMVSLGEDAHFQCP

CD79A

41

P11912
QASFLLPEVMGSDHC

APEX2

291

Q9UBZ4
GATPLIIAAQMCHTD

ANKRD24

181

Q8TF21
SDLQFNAHPLCMVIG

CYB561

46

P49447
PVDTGIQCSISMSEH

DNAI2

46

Q9GZS0
TVTLLDANHCPGSVM

DCLRE1B

91

Q9H816
LKFTCGNHVMEGSLS

CDHR4

101

A6H8M9
LCGNDHVNLPIMETF

ASTE1

221

Q2TB18
SGTSPLACLNAMLHT

ASXL3

46

Q9C0F0
NRPCETLGLSHVAGM

ADAMTS7

351

Q9UKP4
VITGSVDLGVCLHMS

ALG1L

51

Q6GMV1
TFMGLALHCIASVGS

AP2A2

126

O94973
MQSHLAPLACAAAAG

CECR9

1

P0C854
SSGMPNHSASIQLCV

AP3D1

291

O14617
QAEAGGMHTVCLSKS

RCC1

71

P18754
SCFPTSMHILEGDQG

RBM15B

731

Q8NDT2
CIQMTTGAFIAGNLH

OR5K2

141

Q8NHB8
IQSNCHGPISMDFAI

JAK2

396

O60674
CTSLGFASPLHSLEM

MTCL1

1581

Q9Y4B5
TRAAHMCSAGLAGVI

GCK

376

P35557
SLMLQSSPTFQHAVC

NUP205

1766

Q92621
AISRATGMCPHDIAT

KAT6B

926

Q8WYB5
RTALHLACATGQPEM

ANKRD36C

66

Q5JPF3
SFNCTPIEGMLSHQL

PA2G4

176

Q9UQ80
GCGHSLDNTFLMTKL

RSPH10B

431

P0C881
GCGHSLDNTFLMTKL

RSPH10B2

431

B2RC85
PGSSTIMIHDLCLVF

NUP210

951

Q8TEM1
SVVANGVCHMLAPLS

SLC16A1

336

P53985
GLQVVEHACSVTSLM

ALDH6A1

141

Q02252
LKQCHLSEVITSMGG

ABCC10

1356

Q5T3U5
MSLACLAGTAIHGLE

OTOP3

386

Q7RTS5
GPLHEGCMDQSVSLS

IL1A

41

P01583
QPMHLSGEASTARTC

PTCRA

121

Q6ISU1
AQCRVVNFLGTLSMH

GPR82

86

Q96P67
IGRMLQAFVTATCAH

LRIG1

456

Q96JA1
MDGAICIATALSGNH

NLRC3

1016

Q7RTR2
VPGLTEMAVFSCEAH

MERTK

251

Q12866
AGINTHTTLNMPECV

RPS6KC1

1006

Q96S38
GHPTCLQFTLNMTEA

DPF3

291

Q92784
DVHNGIITDGTLCMT

ELF4

56

Q99607
LQTLCLSAGVHAEIM

HERC2

1971

O95714
THRVDTIGQMSCNPS

MTO1

66

Q9Y2Z2
EVHCVLSLEMAGPAT

FLYWCH1

61

Q4VC44
PSLQVASGESMVLHC

LRRN2

431

O75325
LSHTGIQSQDTMPFC

KIAA1109

2446

Q2LD37
EAGHAACSLMLTQFV

HR

651

O43593
MCLAHSAGVVPTSQS

ECPAS

601

Q5VYK3
CHSQGGLRSLMQLES

EXD2

566

Q9NVH0
TVPSHAGMAEQCLAV

HMGXB3

171

Q12766
FHCLTMGGSDASQVP

GSX2

186

Q9BZM3
LMPGENISLTCSSAH

FCAR

136

P24071
LTVLMCANATGSHRL

JRK

216

O75564
THTVAMSTLNFCGPN

OR3A1

161

P47881
LTHTVAMSTLNFCGP

OR3A2

166

P47893
GAHTVPASACLLQMV

OR51S1

96

Q8NGJ8
LTHTVAMSTLNFCGP

OR3A3

166

P47888
MGIAHLSCSDISINV

OR52B6

201

Q8NGF0
GCMAQIFVLHSFVGS

OR4K1

96

Q8NGD4
SGEHAPDLVIMNSCL

PCED1B

111

Q96HM7
LENHCDMASTLIGTP

NEK4

156

P51957
AHLQQMCSEASGTPA

FAM222B

371

Q8WU58
RDGTTHPAMCLQDLT

CES2

86

O00748
LMGSIVTEIACGRQH

HERC4

291

Q5GLZ8
HFGLSNLTGMNCLVD

GALK2

121

Q01415
NFNTLMAVTGGLCHS

RASGRP4

286

Q8TDF6
GHPCSMLSSLGSEVV

ILDR1

311

Q86SU0
AGCVATLLHDAAMNP

SLC25A28

176

Q96A46
TTLAEVHCPASVGTM

KCNH4

951

Q9UQ05
AVNGRSTSGMIHACL

LNX1

691

Q8TBB1
DLGIMNCSHPLASFS

SELL

266

P14151
MIHDLASQAATICSP

KNTC1

1131

P50748
EESASPARCMIVHQG

MYB

366

P10242
FTHLPGKVAQTACMS

EXOC6B

656

Q9Y2D4
QESIMDAGPVVVHCS

PTPN11

446

Q06124
PTQCSHCTSLMVGLI

CDC42BPB

1036

Q9Y5S2
PSGRAISFHSCMAQL

OR10G8

86

Q8NGN5
GSTCGSMSQTHPVLE

CBFA2T3

16

O75081
SLQGLIHEGTMTSLC

C17orf75

251

Q9HAS0
AFETVHSMDGAICPL

ALAS2

326

P22557
CIQMTTGAFIAGNLH

OR5K1

141

Q8NHB7
MTAILERCSGLHVNS

SBF1

546

O95248
DQATSMSQLHLICGG

FAM171A2

366

A8MVW0
AHCFMTNGTLEPAAE

PRSS36

86

Q5K4E3
LCGTSHAIVGLMANV

SLC37A4

361

O43826
MTLCKAGIHSSNVGV

HEATR3

541

Q7Z4Q2
GLNSGFMIAHCTAAA

HAL

491

P42357
HSSLGCSSLGMVVIA

BRME1

326

Q0VDD7
GHSDCSVSMGNLSPL

E2F3

386

O00716
QSPHIGSFVACMIAL

DOCK5

946

Q9H7D0
LCESVSVHPLQMTGL

CPLANE1

2831

Q9H799
AMSICHRGTGIALSA

SDHC

66

Q99643
GMHSVEVSGSQLCQA

DDX11L8

406

A8MPP1
ATVAHLVGALRSCQM

FADD

156

Q13158
ATRCLMGHSEIVVQG

PRMT6

226

Q96LA8
TPGCVTFVLNDHSMA

ETHE1

136

O95571
QQHAAFIPTGSVLCM

MBNL2

311

Q5VZF2
AVQCQHLEAPSEGTM

SELP

321

P16109
SEGTMDCVHPLTAFA

SELP

331

P16109
LGGNSHTLMIACVSP

KIF4A

301

O95239
HTLMIACVSPADSNL

KIF4A

306

O95239
LGGNSHTLMIACVSP

KIF4B

301

Q2VIQ3
HTLMIACVSPADSNL

KIF4B

306

Q2VIQ3
ETFSCMVGHEALPLA

IGHA2

296

P01877
RDSSPLCMAGVHAGV

DCBLD2

231

Q96PD2
LCMAGVHAGVVSNTL

DCBLD2

236

Q96PD2
SNFGRITHPCMESAE

DNAH9

626

Q9NYC9
RQTSMHLGSLCTGDI

GPATCH2

426

Q9NW75
TQASMVCGVTHDPRV

SDK2

511

Q58EX2
HLQTLSPDMQGAYCT

DUSP5

341

Q16690
MFNIGVALHACGVAT

GSTCD

506

Q8NEC7
SAGTFLCETPVLAMH

IFT140

476

Q96RY7
VFCHGSLVMQNLGET

DDB1

1006

Q16531
ETSPGSCNHQIMSAS

LINC02914

86

Q52M58
TIGSMALTEGALCQH

FAM126B

141

Q8IXS8
MHSIIVSCVNDEPLF

FEZ2

146

Q9UHY8
NVTLLCQSQGGMHTF

LILRA3

341

Q8N6C8
CQSQGGMHTFLLTKE

LILRA3

346

Q8N6C8
MAQPVHSLCSAFGLQ

MUCL3

1

Q3MIW9
DHGIPVSVTDNMFCA

PAMR1

636

Q6UXH9
MGCTPSHSDLVNSVA

PCARE

1

A6NGG8
KALSTCGSHVGVMAL

OR52I2

266

Q8NH67
LDMVQCVLPSSSHAA

NLRP3

701

Q96P20
ASTVEYLPGMLHSNC

SMG8

741

Q8ND04
SSVLGPHTDNMICAV

RSBN1L

716

Q6PCB5
MAACPSGHAAILISG

TAS2R38

286

P59533
ASVGTVLMFRCPSNH

SUSD3

51

Q96L08
SLMTNPVSINCGHSY

TRIM38

21

O00635
PTDCTVTLQVAHMSN

FER1L5

111

A0AVI2
HCQIVNLGAGMDTTF

LCMT1

91

Q9UIC8
SVVSNHLSCQVGIML

SLC16A12

106

Q6ZSM3
LCPMSSHLSLAQGES

PLEKHG4

106

Q58EX7
AAECLPVSNHATNVM

POU1F1

31

P28069
TVHVGDSALMGCVFQ

JAML

31

Q86YT9
LQVVMCHLFTGESLA

FBXL18

641

Q96ME1
LCFSPGLMEASHVVN

HDHD5

391

Q9BXW7
SHFSQLSCMPSLIAQ

PRRC2C

2356

Q9Y520
CHGVLNTDNMSILGL

SELENOO

331

Q9BVL4
SLFTGNGPCEMHSVQ

SIN3B

241

O75182
TLGSVAVTMALHGCD

ST3GAL3

301

Q11203
MSQRDTLVHLFAGGC

SLC25A36

1

Q96CQ1
CHGPAITFMTQAVEA

SH3TC1

801

Q8TE82
TISCMQGGHTTLTLI

SLC41A1

426

Q8IVJ1
VTAGSNHTAVLLMDG

MYCBP2

996

O75592
VMQEGLAHICLVTPS

PELO

141

Q9BRX2
NILGHALLVGTCTEM

PKHD1

2261

P08F94
CTPISMLNHSGVGAF

RNF220

106

Q5VTB9
MLTAVCGSLGSQHTE

SP6

1

Q3SY56
TLCLSAGVHAEIMQS

HERC2P3

701

Q9BVR0
SCFLILAHSNPGELM

MROH2B

301

Q7Z745
TLSFIAHQPMDAICA

CDC42BPA

1401

Q5VT25
AHSSCQMQGGTLLSI

PLA2R1

256

Q13018
LSMALPSGQVCHDQQ

NCKIPSD

366

Q9NZQ3
SLSVCSMPLHSGQGE

TGIF2

126

Q9GZN2
MHSTVDCNGVVSLVG

SCN1A

641

P35498
NIMTTPVCGNHLLEV

ADAMDEC1

416

O15204
DHSCQVIVMGATNRP

ATAD1

226

Q8NBU5
GPFVHIASMCAALLS

CLCN2

206

P51788
FPIDGCTTHMENLAE

CNNM4

731

Q6P4Q7
EGLIVGFVHSMCQTA

VPS51

491

Q9UID3
VLAAVRTLSGMCSGH

UNC45B

196

Q8IWX7
THCGTTMQVAGDQLI

ZP1

331

P60852
GALRTSCHVFMVDPD

RGS12

331

O14924
TPLITVSNHQSCMDD

TAFAZZIN

61

Q16635
GSALACLTHTPSFML

SLCO2B1

571

O94956
HLGPVMCLTVDQISS

KIF21A

1491

Q7Z4S6
LSMLTEAVQCSGAHI

RYR3

1696

Q15413
PVTQEALMEHLTTCF

STOX2

91

Q9P2F5
MLENFALVASLGCGH

ZIK1

56

Q3SY52
TCGAMLTNSGNLIVH

ZBTB44

491

Q8NCP5
VHVNVSGNELCLMTS

TDP2

211

O95551
DNIMTHGLSSLCSGL

SLC25A27

226

O95847
THCTLQAVLSDDGMG

AXL

256

P30530
NCITPGTEFMARLHE

XRN1

131

Q8IZH2
ASHAVTQACSMGELL

WNT6

116

Q9Y6F9
NECIRHSASVPMATG

nan

86

Q8N8P6
QGTPLTFMHQECEAI

NF1

1806

P21359
SINSCSVNGGHEMVV

NFATC3

606

Q12968
GLFHGNEMLCKTVSS

PIK3CD

346

O00329
QGFVLMGSSILTCHD

SEZ6

801

Q53EL9
MGSSILTCHDRQAGS

SEZ6

806

Q53EL9
LMGIVNKVSSSHIGC

POLR1F

131

Q3B726
LCQFSTRVHPDGGSM

ZDHHC11

366

Q9H8X9
AMSVDCLGQHAVLSG

WDR59

21

Q6PJI9
VMVRGHSSQLGCSQF

ZGRF1

951

Q86YA3
LELLTGAGCFTHTVM

TMC6

291

Q7Z403
QLCGHAMVVTGLAVS

WDR31

141

Q8NA23
PVLACAFSHDGQMLV

WDSUB1

241

Q8N9V3
EGVQIRSLSCMVHSG

THSD7B

1321

Q9C0I4
QEVILRCDPSSGHMF

TRBV17

36

A0A087X0K7
VSVATCMAILHVGSA

UBR4

341

Q5T4S7
GLAACMATLTVHPVD

SLC25A19

126

Q9HC21
VTCNATHMTLTIPEF

ZP2

266

Q05996
AIMIHCSLNIPGSSD

TMEM78

116

Q5T7P6
SSVNGMCLDIPAHLS

TCTN2

551

Q96GX1
QIDGSTLRTLCMQHG

TNRC6A

1791

Q8NDV7
LHMCVLGNTTILAEF

TNRC6A

1836

Q8NDV7
NPQNIGDHMLTCSLS

ZNF638

1066

Q14966
TPVMLQTTCAVHSGS

TYSND1

466

Q2T9J0
MNGTHFVLESPLNGC

TGFBR3

491

Q03167
TALHMCVLGNTTILA

TNRC6B

1701

Q9UPQ9
MHLPSFSESQGLNCS

ZNF541

16

Q9H0D2
SGELAHQLAPSRCSM

nan

106

Q8TCH9
CTVDMNIALTTFIPH

AGL

346

P35573
CQEMASVLGTNPHLV

NLRP12

816

P59046
ACTLLGISESHQMGI

MYO5A

311

Q9Y4I1