Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP13A4 ATP2B2 ATP2B4	8.25e-05	11	162	3	GO:0005388
GeneOntologyCellularComponent	acrosomal vesicle	ATP8B3 SPATA31A3 SPATA31A7 DCST1 SPATA31A6 SPATA31A5 SPATA31A1 SPACA3	2.28e-04	206	164	8	GO:0001669
GeneOntologyCellularComponent	presynaptic membrane	NRG1 LRFN1 SLC6A3 SLC6A11 AP2M1 NRXN2 CNTNAP4 ATP2B2 ATP2B4	3.50e-04	277	164	9	GO:0042734
GeneOntologyCellularComponent	presynaptic active zone membrane	NRG1 LRFN1 NRXN2 ATP2B2 ATP2B4	3.72e-04	78	164	5	GO:0048787
GeneOntologyCellularComponent	cell surface	SELE CFH LRFN1 NTRK1 CLSTN2 DSCAML1 SLC6A3 TYRO3 ACE2 TGFBR3 LIFR MELTF IGF2R KCNA5 FCN2 TLN1 ASTN1 PLAUR GPC2 IL4R	4.56e-04	1111	164	20	GO:0009986
GeneOntologyCellularComponent	serine-type endopeptidase complex	CFH FCN2 PLAUR	4.90e-04	20	164	3	GO:1905370
GeneOntologyCellularComponent	serine-type peptidase complex	CFH FCN2 PLAUR	6.54e-04	22	164	3	GO:1905286
GeneOntologyCellularComponent	DNA repair complex	FANCD2 FANCI ASCC3	7.48e-04	23	164	3	GO:1990391
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	2.50e-06	12	161	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	2.50e-06	12	161	4	IPR027970
Domain	ATPase_P-typ_cyto_domN	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.26e-04	35	161	4	IPR023299
Domain	ATPase_P-typ_P_site	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.53e-04	36	161	4	IPR018303
Domain	P_typ_ATPase	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.53e-04	36	161	4	IPR001757
Domain	ATPASE_E1_E2	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.53e-04	36	161	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.81e-04	37	161	4	IPR008250
Domain	E1-E2_ATPase	ATP8B3 ATP13A4 ATP2B2 ATP2B4	2.81e-04	37	161	4	PF00122
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	4.38e-04	4	161	2	IPR022141
Domain	IMS	POLK REV1	4.38e-04	4	161	2	PF00817
Domain	IMS_C	POLK REV1	4.38e-04	4	161	2	PF11799
Domain	UMUC	POLK REV1	4.38e-04	4	161	2	PS50173
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	4.38e-04	4	161	2	PF12424
Domain	Carboxyl_trans	MCCC2 PCCB	4.38e-04	4	161	2	PF01039
Domain	COA_CT_CTER	MCCC2 PCCB	4.38e-04	4	161	2	PS50989
Domain	COA_CT_NTER	MCCC2 PCCB	4.38e-04	4	161	2	PS50980
Domain	COA_CT_N	MCCC2 PCCB	4.38e-04	4	161	2	IPR011762
Domain	COA_CT_C	MCCC2 PCCB	4.38e-04	4	161	2	IPR011763
Domain	-	POLK REV1	4.38e-04	4	161	2	3.30.1490.100
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B4	4.38e-04	4	161	2	IPR006408
Domain	DNA_pol_Y-fam_little_finger	POLK REV1	4.38e-04	4	161	2	IPR017961
Domain	Carboxyl_trans	MCCC2 PCCB	4.38e-04	4	161	2	IPR000022
Domain	Cation_ATPase_N	ATP13A4 ATP2B2 ATP2B4	4.66e-04	18	161	3	PF00690
Domain	Cation_ATPase_N	ATP13A4 ATP2B2 ATP2B4	4.66e-04	18	161	3	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP13A4 ATP2B2 ATP2B4	5.50e-04	19	161	3	IPR004014
Domain	PHOSPHOPANTETHEINE	MEIOC ALDH1L2	7.26e-04	5	161	2	PS00012
Domain	-	TDRD15 TDRD6	1.08e-03	6	161	2	2.40.50.90
Domain	Staphylococal_nuclease_OB-fold	TDRD15 TDRD6	1.08e-03	6	161	2	IPR016071
Domain	UmuC	POLK REV1	1.08e-03	6	161	2	IPR001126
Domain	FN3	LRFN1 COL12A1 DSCAML1 TYRO3 LIFR ASTN1 IL4R	1.13e-03	185	161	7	SM00060
Domain	FN3	LRFN1 COL12A1 DSCAML1 TYRO3 LIFR ASTN1 IL4R	1.72e-03	199	161	7	PS50853
Domain	Epox_hydrolase-like	EPHX1 PPME1	2.00e-03	8	161	2	IPR000639
Domain	FN3_dom	LRFN1 COL12A1 DSCAML1 TYRO3 LIFR ASTN1 IL4R	2.27e-03	209	161	7	IPR003961
Domain	WD40/YVTN_repeat-like_dom	KIF21B STRN SF3B3 CFAP52 RPTOR PLXNA4 MAPKBP1 RIC1 ANAPC4	2.54e-03	335	161	9	IPR015943
Domain	-	ATP8B3 ATP13A4 ATP2B2	2.60e-03	32	161	3	3.40.1110.10
Domain	-	ATP8B3 ATP13A4 ATP2B2	2.60e-03	32	161	3	2.70.150.10
Domain	MAC_perforin	ASTN1 C8A	3.18e-03	10	161	2	IPR001862
Domain	Hydrolase_3	ATP8B3 ATP2B2	3.18e-03	10	161	2	PF08282
Domain	Clathrin_mu	AP2M1 AP5M1	3.18e-03	10	161	2	IPR001392
Domain	Adap_comp_sub	AP2M1 AP5M1	3.86e-03	11	161	2	PF00928
Domain	WD40_repeat_dom	KIF21B STRN SF3B3 CFAP52 RPTOR MAPKBP1 RIC1 ANAPC4	4.30e-03	297	161	8	IPR017986
Domain	MACPF	ASTN1 C8A	4.61e-03	12	161	2	IPR020864
Domain	MACPF	ASTN1 C8A	4.61e-03	12	161	2	SM00457
Domain	HAD-like_dom	ATP8B3 ATP13A4 ATP2B2 ATP2B4	4.84e-03	79	161	4	IPR023214
Domain	-	NRG1 LRFN1 COL12A1 NTRK1 DSCAML1 TYRO3 LIFR MALT1 RBPJ PLXNA4 ASTN1 IL4R SCN3B	4.95e-03	663	161	13	2.60.40.10
Domain	Kinesin_motor_CS	KIF21B KIF1A KIF24	5.27e-03	41	161	3	IPR019821
Domain	MHD	AP2M1 AP5M1	5.41e-03	13	161	2	PS51072
Domain	MHD	AP2M1 AP5M1	5.41e-03	13	161	2	IPR028565
Domain	EGF-like_dom	SELE NRG1 IMPG1 NRXN2 CNTNAP4 ASTN1 C8A	5.92e-03	249	161	7	IPR000742
Domain	Kinesin-like_fam	KIF21B KIF1A KIF24	6.03e-03	43	161	3	IPR027640
Domain	TUDOR	TDRD15 TDRD6	6.28e-03	14	161	2	PF00567
Domain	-	KIF21B KIF1A KIF24	6.43e-03	44	161	3	3.40.850.10
Domain	Kinesin	KIF21B KIF1A KIF24	6.43e-03	44	161	3	PF00225
Domain	KISc	KIF21B KIF1A KIF24	6.43e-03	44	161	3	SM00129
Domain	KINESIN_MOTOR_1	KIF21B KIF1A KIF24	6.43e-03	44	161	3	PS00411
Domain	Kinesin_motor_dom	KIF21B KIF1A KIF24	6.43e-03	44	161	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF21B KIF1A KIF24	6.43e-03	44	161	3	PS50067
Domain	ATPase_P-typ_TM_dom	ATP2B2 ATP2B4	8.19e-03	16	161	2	IPR023298
Domain	-	ATP2B2 ATP2B4	8.19e-03	16	161	2	1.20.1110.10
Domain	Ig-like_fold	NRG1 LRFN1 COL12A1 NTRK1 DSCAML1 TYRO3 LIFR MALT1 RBPJ PLXNA4 ASTN1 IL4R SCN3B	8.22e-03	706	161	13	IPR013783
Domain	-	KIF21B STRN CFAP52 RPTOR PLXNA4 MAPKBP1 RIC1 ANAPC4	8.38e-03	333	161	8	2.130.10.10
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	1.35e-11	6	165	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	1.35e-11	6	165	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	8.94e-08	24	165	5	32212159
Pubmed	A genetic screen for behavioral mutations that perturb dopaminergic homeostasis in mice.	SLC6A3 UNC79 ATP2B2	1.05e-07	3	165	3	16436185
Pubmed	FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.	FANCD2 FANCI REV1	1.05e-07	3	165	3	26187992
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ZNF157 SAMD4B BCORL1 MCCC2 FANCD2 JARID2 HNRNPUL2 FANCI SPEN ANAPC4 SMAD4	3.34e-06	396	165	11	26687479
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EPHX1 PSAT1 KIF1A PNN DSG1 MCCC2 AP3B1 NDUFS1 FANCD2 JARID2 UBA1 AP2M1 IGF2R SF3B3 HNRNPUL2 FANCI RPTOR TLN1 RBPJ TDRD6 SPEN	4.33e-06	1425	165	21	30948266
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 RNGTT ZCCHC8 BCORL1 MCCC2 ZNF546 STRN SF3B3 RPTOR RBPJ POLK SPEN PCNT	5.17e-06	588	165	13	38580884
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EPHX1 AHCYL1 USP24 ANKRD50 AP3B1 UBA1 IGF2R SF3B3 SEC24C MAP4K5 FANCI TLN1 XRN1 ASCC3	7.91e-06	708	165	14	39231216
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	AHCYL1 RNGTT INTS7 ZCCHC8 SAMD4B USP24 ASCC3 SPEN ANAPC4	8.86e-06	282	165	9	23667531
Pubmed	A protein interaction landscape of breast cancer.	DDX60 JARID2 UBA1 AP2M1 IGF2R SEC24C HNRNPUL2 FANCI LOXL2 TLN1 PPME1 ATP2B4 ANAPC4	1.15e-05	634	165	13	34591612
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF1A PNN ZCCHC8 USP24 NDUFS1 IGF2R SEC24C FANCI TLN1 XRN1 ASCC3 SPEN PCNT	1.57e-05	653	165	13	22586326
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 LRFN1 PPRC1 PPP1R3B RTTN IGF2R FANCI RPTOR TLN1 BAMBI GPC2 MAPKBP1 SPEN PREX1 IL4R RIC1 PCNT	2.20e-05	1105	165	17	35748872
Pubmed	Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.	RBPJ GPC2	2.24e-05	2	165	2	28440309
Pubmed	DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.	FANCD2 FANCI	2.24e-05	2	165	2	32269332
Pubmed	Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway.	RBPJ SPEN	2.24e-05	2	165	2	12594956
Pubmed	Microvascular abnormalities in capillaroscopy correlate with higher serum IL-18 and sE-selectin levels in patients with type 1 diabetes complicated by microangiopathy.	SELE IL18	2.24e-05	2	165	2	21526496
Pubmed	FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.	FANCD2 FANCI	2.24e-05	2	165	2	34256011
Pubmed	FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures.	FANCD2 FANCI	2.24e-05	2	165	2	19561358
Pubmed	Binding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPAR.	IGF2R PLAUR	2.24e-05	2	165	2	12665524
Pubmed	Congenital insensitivity to pain with anhidrosis (CIPA): novel mutations of the TRKA (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency.	NTRK1 PKLR	2.24e-05	2	165	2	11668614
Pubmed	Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex.	FANCD2 FANCI	2.24e-05	2	165	2	28636932
Pubmed	Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.	RBPJ SPEN	2.24e-05	2	165	2	30673607
Pubmed	Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.	FANCD2 FANCI	2.24e-05	2	165	2	19465922
Pubmed	Expression and purification of human FANCI and FANCD2 using Escherichia coli cells.	FANCD2 FANCI	2.24e-05	2	165	2	25168188
Pubmed	Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes.	RBPJ SPEN	2.24e-05	2	165	2	21372128
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	2.24e-05	2	165	2	1313367
Pubmed	Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.	FANCD2 FANCI	2.24e-05	2	165	2	24278431
Pubmed	FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.	FANCD2 FANCI	2.24e-05	2	165	2	39085614
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	2.24e-05	2	165	2	22252018
Pubmed	Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity.	PDE4D PDE5A	2.24e-05	2	165	2	14668322
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	2.24e-05	2	165	2	25690014
Pubmed	Structural insight into FANCI-FANCD2 monoubiquitination.	FANCD2 FANCI	2.24e-05	2	165	2	32725171
Pubmed	Mechanism, specificity, and function of FANCD2-FANCI ubiquitination and deubiquitination.	FANCD2 FANCI	2.24e-05	2	165	2	34137174
Pubmed	Homocysteine inhibits neural stem cells survival by inducing DNA interstrand cross-links via oxidative stress.	FANCD2 FANCI	2.24e-05	2	165	2	27773793
Pubmed	FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.	FANCD2 FANCI	2.24e-05	2	165	2	26430909
Pubmed	Design, synthesis and biological evaluation of novel 1,2,4a,5-tetrahydro-4H-benzo[b][1,4]oxazino[4,3-d][1,4]oxazine-based AAK1 inhibitors with anti-viral property against SARS-CoV-2.	ACE2 AP2M1	2.24e-05	2	165	2	38377825
Pubmed	Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays.	FANCD2 FANCI	2.24e-05	2	165	2	32167469
Pubmed	FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.	FANCD2 FANCI	2.24e-05	2	165	2	29059323
Pubmed	HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease - Insights from randomized clinical trials and human genetics.	CETP AP3B1	2.24e-05	2	165	2	34637926
Pubmed	FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.	FANCD2 FANCI	2.24e-05	2	165	2	17460694
Pubmed	The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2.	FANCD2 FANCI	2.24e-05	2	165	2	27405460
Pubmed	Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus.	POLK REV1	2.24e-05	2	165	2	19628463
Pubmed	Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.	FANCD2 FANCI	2.24e-05	2	165	2	21764741
Pubmed	Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.	ATP2B2 ATP2B4	2.24e-05	2	165	2	16216224
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	NCOA3 PDE4D PNN ZCCHC8 SAMD4B USP24 UBA1 HNRNPUL2 FANCI RPTOR SPEN	3.09e-05	503	165	11	16964243
Pubmed	A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).	SELE IL18 CETP IGF2R PLAUR IL4R VEGFB	3.19e-05	186	165	7	20673868
Pubmed	Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.	SELE IL18 CETP IGF2R PLAUR IL4R VEGFB	3.19e-05	186	165	7	20452482
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NCOA3 LCORL ZCCHC8 BCORL1 USP24 MCCC2 XRN1 ASCC3 PCCB PCNT	3.38e-05	418	165	10	34709266
Pubmed	Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.	EPHX1 NCOA3 CETP SLC6A3 IGF2R IL4R	6.01e-05	141	165	6	18636124
Pubmed	Transcriptional regulation of the TGF-beta pseudoreceptor BAMBI by TGF-beta signaling.	BAMBI SMAD4	6.69e-05	3	165	2	15240101
Pubmed	Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.	UNC79 UNC80	6.69e-05	3	165	2	26708753
Pubmed	Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).	UNC79 UNC80	6.69e-05	3	165	2	30167850
Pubmed	The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.	ERG RBPJ	6.69e-05	3	165	2	28695891
Pubmed	Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors.	FANCD2 FANCI	6.69e-05	3	165	2	29030393
Pubmed	Interleukin-4, interleukin-4 receptor, and interleukin-18 polymorphisms and rheumatoid arthritis: a meta-analysis.	IL18 IL4R	6.69e-05	3	165	2	23883285
Pubmed	FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.	FANCD2 FANCI	6.69e-05	3	165	2	20671156
Pubmed	The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI.	FANCD2 FANCI	6.69e-05	3	165	2	21355096
Pubmed	Genetic variants of complement genes ficolin-2, mannose-binding lectin and complement factor H are associated with leprosy in Han Chinese from Southwest China.	CFH FCN2	6.69e-05	3	165	2	23423485
Pubmed	Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ.	POLK REV1	6.69e-05	3	165	2	22700975
Pubmed	Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.	ASTL SPACA3	6.69e-05	3	165	2	22206759
Pubmed	Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.	UNC79 UNC80	6.69e-05	3	165	2	21040849
Pubmed	Generation of a conditional knockout allele for mammalian Spen protein Mint/SHARP.	RBPJ SPEN	6.69e-05	3	165	2	17457934
Pubmed	Mechanism of RAD51-dependent DNA interstrand cross-link repair.	FANCD2 FANCI	6.69e-05	3	165	2	21719678
Pubmed	Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.	UNC79 UNC80	6.69e-05	3	165	2	32620897
Pubmed	Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.	FANCD2 FANCI	6.69e-05	3	165	2	25489943
Pubmed	A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.	FANCD2 FANCI	6.69e-05	3	165	2	31219578
Pubmed	Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.	FANCD2 FANCI	6.69e-05	3	165	2	22855611
Pubmed	Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination.	FANCD2 FANCI	6.69e-05	3	165	2	34828369
Pubmed	Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.	POLK REV1	6.69e-05	3	165	2	26982350
Pubmed	CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression.	LIFR CELF2	6.69e-05	3	165	2	36104590
Pubmed	Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.	RBPJ SPEN	6.69e-05	3	165	2	17242367
Pubmed	Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction.	IGF2R PLAUR	6.69e-05	3	165	2	9566979
Pubmed	Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.	POLK REV1	6.69e-05	3	165	2	25080294
Pubmed	SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway.	RBPJ SPEN	6.69e-05	3	165	2	12374742
Pubmed	Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism.	FANCD2 FANCI	6.69e-05	3	165	2	28684355
Pubmed	The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.	ATP2B2 ATP2B4	6.69e-05	3	165	2	17689535
Pubmed	Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.	ATP2B2 ATP2B4	6.69e-05	3	165	2	20211863
Pubmed	The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition.	MEIOC XRN1	6.69e-05	3	165	2	35305312
Pubmed	Inactivation of ribosomal protein S27-like impairs DNA interstrand cross-link repair by destabilization of FANCD2 and FANCI.	FANCD2 FANCI	6.69e-05	3	165	2	33051438
Pubmed	Oxidative Stress Induces E-Selectin Expression through Repression of Endothelial Transcription Factor ERG.	SELE ERG	6.69e-05	3	165	2	37930129
Pubmed	Regulation of m6A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.	MEIOC XRN1	6.69e-05	3	165	2	29033321
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	NSUN4 AP3B1 IGF2R USP32 PPME1 ASCC3 NME7	7.29e-05	212	165	7	33462405
Pubmed	Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.	PPP1R3B CETP USP24	8.12e-05	18	165	3	23726366
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	AHCYL1 IL18 PNN DSG1 MCCC2 NDUFS1 UBA1 AP2M1 SF3B3 SEC24C HNRNPUL2 MAP4K5 FANCI RPTOR TLN1 XRN1 ASCC3 NME7	8.21e-05	1353	165	18	29467282
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	AHCYL1 PSAT1 USP24 CDK14 NDUFS1 FANCD2 UBA1 IGF2R SEC24C COG1 FANCI TLN1 GSTCD PPME1	8.25e-05	878	165	14	37223481
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CLPSL2 LIFR FANCI ISCU PKLR EFCAB7	9.11e-05	152	165	6	34299191
Pubmed	Lung cancer susceptibility model based on age, family history and genetic variants.	IL18 SLC6A3 REV1	9.61e-05	19	165	3	19390575
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	NRG1 NSUN4 NEUROD4 NTRK1 SLC6A3 SLC6A11 NRXN2 ASTN1	9.94e-05	300	165	8	19086053
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DSCAML1 RBM12 NRXN2 TLN1 PREX1 UNC80 PCNT	1.06e-04	225	165	7	12168954
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	PSAT1 CETP CTSC FTCD ACE2 TGFBR3 MELTF UBA1 AP2M1 IGF2R FCN2 TLN1 GSTCD PKLR SPEN	1.08e-04	1016	165	15	19056867
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B2 ATP2B4	1.33e-04	4	165	2	12209837
Pubmed	Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.	IGF2R PLAUR	1.33e-04	4	165	2	19037107
Pubmed	Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.	EPHX1 SFTPB	1.33e-04	4	165	2	15817713
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B2 ATP2B4	1.33e-04	4	165	2	12784250
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B2 ATP2B4	1.33e-04	4	165	2	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B4	1.33e-04	4	165	2	8245032
Pubmed	FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation.	FANCD2 FANCI	1.33e-04	4	165	2	26336824
Pubmed	Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system.	PDE4D PDE5A	1.33e-04	4	165	2	15938621
Pubmed	The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.	KIF1A NTRK1	1.33e-04	4	165	2	27263974
Cytoband	6q16	RNGTT ASCC3	1.27e-04	5	165	2	6q16
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	3.54e-04	8	165	2	chr9q12
GeneFamily	Fibronectin type III domain containing	LRFN1 COL12A1 DSCAML1 TYRO3 LIFR ASTN1	3.98e-04	160	108	6	555
Coexpression	GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN	NCOA3 IL18 PDE4D JARID2 RPTOR XRN1 PLXNA4 PLAUR IL4R	4.00e-06	197	162	9	M8133
Coexpression	GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN	ZNF157 ZFAND4 ZNF546 RND3 SLC25A40 SHPRH AP5M1 POLK EFCAB7	4.53e-06	200	162	9	M9777
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NCOA3 NRG1 RNGTT USP24 AP3B1 JARID2 TGFBR3 MALT1 IGF2R MAP4K5 RBPJ PLAUR ASCC3 SPEN ATP2B4 SMAD4 PCNT CHST3	6.30e-06	856	162	18	M4500
Coexpression	YAGI_AML_WITH_INV_16_TRANSLOCATION	MON2 SELE ERG PNLIPRP1 PNN NTRK1 SLC6A11 MELTF KCNA5 SLC25A40 MAPKBP1 SPEN	1.02e-05	411	162	12	M1047
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN	NRG1 RNGTT PPP1R3B CDK14 JARID2 CELF2 LOXL2 RBPJ XRN1 ASCC3 PCCB IL4R	1.92e-05	438	162	12	M227
Coexpression	GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN	EPHX1 ZCCHC8 CTSC ZBTB41 ANKRD50 AP2M1 PLAUR ASCC3	3.62e-05	200	162	8	M5073
Coexpression	PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP	CFH EPHX1 IL18 COL12A1 CETP CTSC RND3 LIFR	5.28e-05	211	162	8	M12225
Coexpression	GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN	MON2 KIF21B NARF SLC25A40 MAP4K5 SHPRH EFCAB7	5.67e-05	157	162	7	M6871
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 COL12A1 FIGN DSCAML1 MELTF ASXL3 CNTNAP4 UNC79 UNC80	3.04e-08	184	165	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 COL12A1 FIGN DSCAML1 MELTF ASXL3 CNTNAP4 UNC79 UNC80	3.04e-08	184	165	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 COL12A1 FIGN DSCAML1 MELTF ASXL3 CNTNAP4 UNC79 UNC80	3.04e-08	184	165	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SELE PNLIPRP1 IMPG1 FTCD SLC6A3 PLAUR	5.74e-07	81	165	6	20796e59cdeb398e7772f4356578d74a33405f71
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH EPHX1 NRG1 CTSC CLSTN2 CPED1 LOXL2 BAMBI	7.47e-07	197	165	8	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IL18 NTRK1 GPRC6A TG CELF2 UGT3A2 ATP2B2	7.71e-07	136	165	7	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRG1 KIF1A DSCAML1 SLC25A15 BAMBI UNC79 UNC80	3.04e-06	167	165	7	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NMNAT2 LRFN1 BCORL1 NRXN2 SHISAL2A ATP2B2 SCN3B	5.96e-06	185	165	7	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 CLSTN2 TYRO3 CELF2 ASXL3 ATP2B4 SCN3B	6.17e-06	186	165	7	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CPED1 RND3 TGFBR3 IGF2R CELF2 PDE5A ATP2B4	6.86e-06	189	165	7	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NMNAT2 GPRC6A CLSTN2 TGFBR3 LOXL2 PDE5A ATP2B4	7.34e-06	191	165	7	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	LCORL ZBTB41 ANKRD50 NDUFS1 STRN IGF2R USP32	7.86e-06	193	165	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CPED1 RND3 TGFBR3 RBPJ XRN1 ASCC3	8.41e-06	195	165	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGF2R CELF2 TLN1 USP32 PLAUR PREX1 IL4R	8.98e-06	197	165	7	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial-Proteoglycan-expressing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFH COL12A1 CTSC CPED1 TGFBR3 LOXL2 PDE5A	9.91e-06	200	165	7	94ef227b2162ba77af33b8cc8aaa4a7e3bdf79a7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFH COL12A1 CTSC CPED1 TGFBR3 LOXL2 PDE5A	9.91e-06	200	165	7	429028c3112d279b26abf3296e01b1884b4b7fcb
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	JARID2 MAP4K5 ASXL3 C16orf87 RBPJ SPEN	1.98e-05	149	165	6	768877bade04ca0321593b8470b5011ad8270431
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZNF157 RTTN KIF24 TESMIN FANCI CDHR4	2.66e-05	157	165	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 DSCAML1 CNTNAP4 ASTN1 TDRD6 UNC80	2.95e-05	160	165	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 DSCAML1 CNTNAP4 ASTN1 TDRD6 UNC80	2.95e-05	160	165	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRG1 ASXL3 BAMBI C8A UNC79 UNC80	3.39e-05	164	165	6	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHX1 CLSTN2 SAPCD1 IGF2R GSTCD PDE5A	3.75e-05	167	165	6	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRG1 KIF1A DSCAML1 BAMBI UNC79 UNC80	4.01e-05	169	165	6	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	ATP13A4 LCORL FANCD2 COG1 FANCI GSTCD	4.15e-05	170	165	6	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ATP13A4 AHCYL1 SLC6A11 ACSM5 C8A	4.48e-05	105	165	5	c41264e8b7d306d5d3ffa5b29eb36c7131d1cedf
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ATP13A4 AHCYL1 SLC6A11 ACSM5 C8A	4.48e-05	105	165	5	ed570cfdd452767dfb4dcae72282fe0fb25a4029
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ATP13A4 AHCYL1 SLC6A11 ACSM5 C8A	4.48e-05	105	165	5	ed3a431195c42c96c7d9c420e4b9fb00f415012d
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ZCCHC8 LINS1 MELTF SEC24C SLC25A15 USP32	4.72e-05	174	165	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH COL12A1 FIGN CPED1 CELF2 CDHR4	4.87e-05	175	165	6	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	NRG1 KIF1A TESMIN ASXL3 UNC79 UNC80	4.87e-05	175	165	6	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	NRG1 KIF1A TESMIN ASXL3 UNC79 UNC80	4.87e-05	175	165	6	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC39 PDE4D TG MELTF NRXN2 PLXNA4	5.19e-05	177	165	6	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC39 PDE4D TG MELTF NRXN2 PLXNA4	5.19e-05	177	165	6	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC39 PDE4D TG MELTF NRXN2 PLXNA4	5.19e-05	177	165	6	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 CLSTN2 BAMBI ATP2B4 IL4R SCN3B	5.70e-05	180	165	6	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFH COL12A1 CNTNAP4 FHIP1A SCN3B PCNT	5.70e-05	180	165	6	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	NRG1 ATP13A4 IL18 COL12A1 SFTPB FHIP1A	6.24e-05	183	165	6	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMNAT2 RTTN CLSTN2 ASTL LOXL2 PDE5A	6.24e-05	183	165	6	0e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMNAT2 RTTN CLSTN2 ASTL LOXL2 PDE5A	6.24e-05	183	165	6	cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 PDE4D CNTNAP4 UNC79 ATP2B2 UNC80	7.04e-05	187	165	6	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	NRG1 PSAT1 FTCD FIGN ACE2 MALT1	7.04e-05	187	165	6	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PDE4D CTSC RTTN FIGN JARID2 BAMBI	7.04e-05	187	165	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NMNAT2 RND3 AP2M1 PLXNA4 GPC2 SCN3B	7.04e-05	187	165	6	85645de9069bd9a8a02d53b0d3d73bf9c2b57189
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL12A1 ERG CLSTN2 CPED1 PLXNA4 UNC80	7.04e-05	187	165	6	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 CPED1 TGFBR3 CELF2 XRN1 SHPRH	7.25e-05	188	165	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 CPED1 TGFBR3 CELF2 XRN1 SHPRH	7.25e-05	188	165	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 CPED1 TGFBR3 CELF2 XRN1 SHPRH	7.25e-05	188	165	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 SFTPB CTSC CLSTN2 FIGN FHIP1A	7.25e-05	188	165	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	CFH COL12A1 ERG TGFBR3 PLXNA4 UNC80	7.46e-05	189	165	6	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH EPHX1 CPED1 LIFR IGF2R ATP2B4	7.46e-05	189	165	6	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CLSTN2 DSCAML1 RND3 NRXN2 GPC2 SCN3B	7.46e-05	189	165	6	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	NRG1 CLSTN2 FTCD FIGN DSCAML1 MALT1	7.46e-05	189	165	6	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RTTN KIF24 MELTF TESMIN FANCI PCNT	7.68e-05	190	165	6	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RTTN KIF24 MELTF TESMIN FANCI PCNT	7.68e-05	190	165	6	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERG CPED1 KIF24 FANCD2 FANCI PLXNA4	8.37e-05	193	165	6	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CTSC TRDC TGFBR3 IGF2R ATP2B4 PCNT	8.62e-05	194	165	6	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RTTN KIF24 MELTF TESMIN FANCI PCNT	8.62e-05	194	165	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 TGFBR3 CELF2 LOXL2 PLXNA4 PDE5A	8.86e-05	195	165	6	2514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHCYL1 RND3 TGFBR3 IGF2R LOXL2 PPME1	9.11e-05	196	165	6	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH CTSC ANKRD50 RND3 TGFBR3 LOXL2	9.11e-05	196	165	6	a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 TGFBR3 CELF2 LOXL2 PLXNA4 PDE5A	9.11e-05	196	165	6	e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 TGFBR3 CELF2 LOXL2 PLXNA4 PDE5A	9.11e-05	196	165	6	f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PDE4D CTSC FIGN RND3 LIFR	9.11e-05	196	165	6	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHCYL1 PSAT1 KIF1A TYRO3 SLC6A11 PREX1	9.11e-05	196	165	6	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NMNAT2 KIF1A ASXL3 ASTN1 UNC79 UNC80	9.11e-05	196	165	6	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH COL12A1 ERG FIGN CPED1 RND3	9.11e-05	196	165	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHCYL1 RND3 TGFBR3 IGF2R LOXL2 PPME1	9.11e-05	196	165	6	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH COL12A1 ERG FIGN CPED1 RND3	9.11e-05	196	165	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH NRG1 CTSC CLSTN2 CPED1 LOXL2	9.37e-05	197	165	6	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH EPHX1 CTSC CPED1 RND3 LOXL2	9.37e-05	197	165	6	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	LRRC39 DDX60 TGFBR3 NRXN2 GSTCD ATP2B4	9.64e-05	198	165	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH COL12A1 CTSC CLSTN2 RND3 LOXL2	9.64e-05	198	165	6	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NMNAT2 CDK14 CELF2 UNC79 ATP2B2 UNC80	9.64e-05	198	165	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NMNAT2 CDK14 CELF2 UNC79 ATP2B2 UNC80	9.64e-05	198	165	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NMNAT2 CDK14 CELF2 UNC79 ATP2B2 UNC80	9.64e-05	198	165	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPED1 RND3 IGF2R CELF2 LOXL2 PDE5A	9.64e-05	198	165	6	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH EPHX1 COL12A1 RND3 LIFR LOXL2	9.91e-05	199	165	6	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MON2 PNN RTTN USP24 TGFBR3 CELF2	9.91e-05	199	165	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH EPHX1 COL12A1 RND3 LIFR LOXL2	9.91e-05	199	165	6	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH EPHX1 COL12A1 RND3 TGFBR3 LOXL2	9.91e-05	199	165	6	6200618e029063486719479c41eaf31798bd13cf
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NMNAT2 CPED1 TGFBR3 NRXN2 PLXNA4 PDE5A	9.91e-05	199	165	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	E16.5-Mesenchymal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPED1 RND3 IGF2R CELF2 LOXL2 PDE5A	9.91e-05	199	165	6	ebd9ca151434f5ca27a82d4f1815a1ea500c1989
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH EPHX1 COL12A1 RND3 LIFR LOXL2	9.91e-05	199	165	6	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CFH COL12A1 CTSC RND3 LIFR CELF2	9.91e-05	199	165	6	56d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial\|2m / Sample Type, Dataset, Time_group, and Cell type.	CFH COL12A1 CPED1 LOXL2 PDE5A PLAUR	1.02e-04	200	165	6	3da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	NMNAT2 CDK14 CELF2 UNC79 ATP2B2 UNC80	1.02e-04	200	165	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NMNAT2 KIF1A NRXN2 PLXNA4 SCN3B	1.02e-04	200	165	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	CFH COL12A1 CPED1 LOXL2 PDE5A PLAUR	1.02e-04	200	165	6	eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH COL12A1 CLSTN2 CPED1 TGFBR3 CELF2	1.02e-04	200	165	6	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NMNAT2 ANKRD50 NRXN2 ASXL3 SCN3B	1.02e-04	200	165	6	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	KIF21B DDX60 USP24 TGFBR3 IGF2R ATP2B4	1.02e-04	200	165	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	INTS7 CLSTN2 RPTOR ANKEF1 TDRD6	1.11e-04	127	165	5	9071cd0953c8bb6746dc9cd13d153e3d6ef40b08
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	TDRD15 ZCCHC8 CETP MAP4K5 POLK	7.71e-06	51	157	5	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	triglycerides in IDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	1.46e-05	58	157	5	EFO_0022149
Disease	phospholipids in VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	1.59e-05	59	157	5	EFO_0022301
Disease	interstitial lung disease (is_implicated_in)	SFTPB AP3B1 IL4R	1.73e-05	10	157	3	DOID:3082 (is_implicated_in)
Disease	respiratory syncytial virus infectious disease (is_implicated_in)	IL18 SFTPB ACE2	1.73e-05	10	157	3	DOID:1273 (is_implicated_in)
Disease	total lipids in VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	1.73e-05	60	157	5	EFO_0022314
Disease	free cholesterol in VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	1.87e-05	61	157	5	EFO_0022276
Disease	cysteine-rich with EGF-like domain protein 1 measurement	FANCD2 SLC6A11 ATP2B2 ATP2B4	2.47e-05	32	157	4	EFO_0021870
Disease	cholesterol in large VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	2.55e-05	65	157	5	EFO_0021902
Disease	cholesterol in very large VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	2.55e-05	65	157	5	EFO_0022230
Disease	cerebral malaria (is_implicated_in)	NRG1 ACE2	2.81e-05	2	157	2	DOID:14069 (is_implicated_in)
Disease	total lipids in small VLDL	TDRD15 CETP IGF2R MAP4K5 PCCB	2.96e-05	67	157	5	EFO_0022148
Disease	triglycerides in very small VLDL measurement	TDRD15 CETP IGF2R MAP4K5 PCCB	3.18e-05	68	157	5	EFO_0022144
Disease	schizophrenia (implicated_via_orthology)	NRG1 CTSC SLC6A3 ASTN1 CHST3	3.18e-05	68	157	5	DOID:5419 (implicated_via_orthology)
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	TDRD15 ZCCHC8 CETP MAP4K5 POLK	3.42e-05	69	157	5	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	triglycerides in large LDL measurement	TDRD15 IGF2R MAP4K5 PCCB	8.10e-05	43	157	4	EFO_0022319
Disease	leukemia inhibitory factor receptor measurement	CFH LIFR	8.41e-05	3	157	2	EFO_0010788
Disease	Malignant neoplasm of prostate	EPHX1 NCOA3 IL18 PDE4D ERG LIFR IGF2R CELF2 GSTCD PLAUR POLK SPEN	1.20e-04	616	157	12	C0376358
Disease	Prostatic Neoplasms	EPHX1 NCOA3 IL18 PDE4D ERG LIFR IGF2R CELF2 GSTCD PLAUR POLK SPEN	1.20e-04	616	157	12	C0033578
Disease	Hypertriglyceridemia	TDRD15 CETP MAP4K5	1.35e-04	19	157	3	EFO_0004211
Disease	phospholipids in medium LDL measurement	TDRD15 CETP IGF2R MAP4K5	1.36e-04	49	157	4	EFO_0022183
Disease	triglycerides to total lipids in medium LDL percentage	CETP MAP4K5 POLK PCCB	1.47e-04	50	157	4	EFO_0022334
Disease	Intellectual Disability	ZCCHC8 RNF113A RTTN SLC6A3 ACE2 LINS1 AP2M1 NRXN2 ASTN1 ASCC3	1.49e-04	447	157	10	C3714756
Disease	endoglin measurement	CFH PLAUR	1.68e-04	4	157	2	EFO_0008118
Disease	hereditary sensory neuropathy (is_implicated_in)	KIF1A NTRK1	1.68e-04	4	157	2	DOID:0050548 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TDRD15 CETP USP24 IGF2R MAP4K5 PLAUR PCCB VEGFB	1.75e-04	291	157	8	EFO_0008317, EFO_0020946
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TDRD15 CETP USP24 IGF2R MAP4K5 PCCB VEGFB	1.95e-04	222	157	7	EFO_0008317, EFO_0020943
Disease	total lipids in medium VLDL	TDRD15 CETP IGF2R MAP4K5	1.98e-04	54	157	4	EFO_0022153
Disease	myocardial infarction (biomarker_via_orthology)	IL18 ACE2 PLAUR C8A IL4R SMAD4	2.23e-04	160	157	6	DOID:5844 (biomarker_via_orthology)
Disease	phospholipids:total lipids ratio	TDRD15 CETP USP24 IGF2R MAP4K5 PCCB VEGFB	2.23e-04	227	157	7	EFO_0020946
Disease	triglycerides in LDL measurement	TDRD15 IGF2R MAP4K5 PCCB	2.28e-04	56	157	4	EFO_0022320
Disease	cholesterol to total lipids in large LDL percentage	TDRD15 CETP MAP4K5 POLK	2.28e-04	56	157	4	EFO_0022235
Disease	low density lipoprotein particle size measurement	TDRD15 CETP MAP4K5 POLK	2.62e-04	58	157	4	EFO_0008593
Disease	triglycerides to total lipids in small VLDL percentage	TDRD15 CETP MAP4K5 VEGFB	2.62e-04	58	157	4	EFO_0022338
Disease	cholesterol to total lipids in IDL percentage	MAP4K5 POLK PCCB VEGFB	2.98e-04	60	157	4	EFO_0022233
Disease	triglycerides in small VLDL measurement	TDRD15 CETP MAP4K5 PCCB	3.18e-04	61	157	4	EFO_0022145
Disease	free cholesterol in very large VLDL measurement	TDRD15 CETP MAP4K5 PCCB	3.18e-04	61	157	4	EFO_0022274
Disease	triglyceride measurement, intermediate density lipoprotein measurement	CETP RBM12 IGF2R MAP4K5 PCCB	3.26e-04	111	157	5	EFO_0004530, EFO_0008595
Disease	phospholipids in large VLDL measurement	TDRD15 CETP MAP4K5 PCCB	3.38e-04	62	157	4	EFO_0022169
Disease	triglycerides in medium LDL measurement	TDRD15 IGF2R MAP4K5 PCCB	3.38e-04	62	157	4	EFO_0022322
Disease	phospholipids in very large VLDL measurement	TDRD15 CETP MAP4K5 PCCB	3.38e-04	62	157	4	EFO_0022299
Disease	lipoprotein A measurement	TDRD15 CETP DSCAML1 IGF2R PCCB	3.39e-04	112	157	5	EFO_0006925
Disease	Micronuclei, Chromosome-Defective	EPHX1 SLC6A3 POLK	3.51e-04	26	157	3	C1449861
Disease	Micronuclei, Genotoxicant-Induced	EPHX1 SLC6A3 POLK	3.51e-04	26	157	3	C1449862
Disease	free cholesterol to total lipids in medium LDL percentage	CETP MAP4K5 PCCB VEGFB	3.60e-04	63	157	4	EFO_0022283
Disease	Liver carcinoma	EPHX1 CETP CDK14 FANCD2 RND3 LIFR IGF2R FCN2 FANCI CNTNAP4	4.05e-04	507	157	10	C2239176
Disease	NTF2-related export protein 1 measurement	CFH NRG1	4.16e-04	6	157	2	EFO_0801847
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B4	4.16e-04	6	157	2	DOID:0050429 (implicated_via_orthology)
Disease	total lipids in large VLDL	TDRD15 CETP MAP4K5 PCCB	4.56e-04	67	157	4	EFO_0022175
Disease	free cholesterol in large VLDL measurement	TDRD15 CETP MAP4K5 PCCB	4.82e-04	68	157	4	EFO_0022265
Disease	complement factor H-related protein 2 measurement	CFH COL12A1 ZBTB41	4.88e-04	29	157	3	EFO_0600055
Disease	pulmonary hypertension (is_implicated_in)	ACE2 KCNA5 VEGFB	5.40e-04	30	157	3	DOID:6432 (is_implicated_in)
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	EPHX1 GGT3P	5.80e-04	7	157	2	DOID:5022 (biomarker_via_orthology)
Disease	anosmin-1 measurement	CFH NRG1	5.80e-04	7	157	2	EFO_0802284
Disease	TNF-related apoptosis-inducing ligand measurement	CFH DSG1 ASXL3 PLAUR	5.99e-04	72	157	4	EFO_0008300
Disease	Amphetamine-Related Disorders	EPHX1 NRG1 PDE4D SLC6A3	6.99e-04	75	157	4	C0236733
Disease	Amphetamine Abuse	EPHX1 NRG1 PDE4D SLC6A3	6.99e-04	75	157	4	C0236807
Disease	Amphetamine Addiction	EPHX1 NRG1 PDE4D SLC6A3	6.99e-04	75	157	4	C0236804
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 CETP MAP4K5 ASXL3 PLAUR PCCB	7.28e-04	200	157	6	EFO_0004611, EFO_0020945
Disease	E3 ubiquitin-protein ligase RNF13 measurement	CFH NRG1	7.71e-04	8	157	2	EFO_0801556
Disease	central serous retinopathy	CFH PREX1	7.71e-04	8	157	2	EFO_0009784
Disease	tyrosine-protein kinase receptor TYRO3 measurement	CFH TYRO3	7.71e-04	8	157	2	EFO_0020829
Disease	neurexophilin-1 measurement	CFH C8A	7.71e-04	8	157	2	EFO_0008244
Disease	programmed cell death 1 ligand 2 measurement	CFH RIC1	7.71e-04	8	157	2	EFO_0008268
Disease	opioid-binding protein/cell adhesion molecule measurement	CFH MAP4K5	7.71e-04	8	157	2	EFO_0020618
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 USP24 IGF2R MAP4K5 PLAUR	8.50e-04	137	157	5	EFO_0004611, EFO_0008591
Disease	free cholesterol in small HDL measurement	TDRD15 CETP MAP4K5	8.54e-04	35	157	3	EFO_0022270
Disease	Schizophrenia	NRG1 PSAT1 IL18 PDE4D NTRK1 NDUFS1 SLC6A3 JARID2 LIFR SLC6A11 CELF2 NRXN2 PCNT	9.17e-04	883	157	13	C0036341
Disease	pulmonary tuberculosis (is_marker_for)	IL18 PLAUR IL4R	9.28e-04	36	157	3	DOID:2957 (is_marker_for)
Disease	Idiopathic pulmonary hypertension	KCNA5 SMAD4	9.88e-04	9	157	2	C0152171
Disease	DCN1-like protein 5 measurement	CFH MAP4K5	9.88e-04	9	157	2	EFO_0801520
Disease	apolipoprotein A-V measurement	CETP MAP4K5	9.88e-04	9	157	2	EFO_0801387
Disease	leukocyte immunoglobulin-like receptor subfamily A member 5 measurement	CFH MAP4K5	9.88e-04	9	157	2	EFO_0801766
Disease	Endomyocardial Fibrosis	ACE2 IGF2R	9.88e-04	9	157	2	C0553980
Disease	cholesteryl esters to total lipids in medium LDL percentage	CETP IGF2R MAP4K5	1.01e-03	37	157	3	EFO_0022252
Disease	triglyceride measurement, C-reactive protein measurement	CETP MAP4K5 PCCB	1.09e-03	38	157	3	EFO_0004458, EFO_0004530
Disease	lipoprotein measurement, phospholipid measurement	TDRD15 CETP MAP4K5 POLK	1.12e-03	85	157	4	EFO_0004639, EFO_0004732
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	TDRD15 CETP RBM12 IGF2R MAP4K5 PCCB	1.19e-03	220	157	6	EFO_0004529, EFO_0008317
Disease	level of phosphatidylcholine	CETP MAP4K5	1.23e-03	10	157	2	OBA_2040179
Disease	WNT1-inducible-signaling pathway protein 1 measurement	TG C8A	1.23e-03	10	157	2	EFO_0008321
Disease	1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) measurement	CETP MAP4K5	1.23e-03	10	157	2	EFO_0800464
Disease	Fanconi anemia (is_implicated_in)	FANCD2 FANCI	1.23e-03	10	157	2	DOID:13636 (is_implicated_in)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	TDRD15 CETP MAP4K5 PLAUR PCCB	1.27e-03	150	157	5	EFO_0004611, EFO_0020947
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	TDRD15 CETP USP24 IGF2R MAP4K5 PLAUR	1.34e-03	225	157	6	EFO_0008317, EFO_0020947
Disease	autism spectrum disorder (implicated_via_orthology)	DSCAML1 SLC6A3 NRXN2 CNTNAP4 PREX1	1.35e-03	152	157	5	DOID:0060041 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	TDRD15 CETP RBM12 IGF2R MAP4K5 PCCB	1.46e-03	229	157	6	EFO_0004639, EFO_0008317
Disease	aortic valve stenosis (is_marker_for)	JARID2 BAMBI	1.50e-03	11	157	2	DOID:1712 (is_marker_for)
Disease	gastrin-releasing peptide measurement	CFH NRG1	1.50e-03	11	157	2	EFO_0022000
Disease	amino acid metabolic disorder (is_implicated_in)	SLC25A15 PCCB	1.50e-03	11	157	2	DOID:9252 (is_implicated_in)
Disease	hemopexin measurement	CFH ZBTB41	1.50e-03	11	157	2	EFO_0008149
Disease	Situs Inversus	CFAP52 NME7	1.50e-03	11	157	2	C0037221
Disease	receptor-interacting serine/threonine-protein kinase 2 measurement	CFH NRG1	1.50e-03	11	157	2	EFO_0802997
Disease	cholesteryl esters to total lipids in small HDL percentage	CETP MAP4K5 PCCB	1.56e-03	43	157	3	EFO_0022254
Disease	cholesterol to total lipids in large VLDL percentage	TDRD15 CETP MAP4K5	1.78e-03	45	157	3	EFO_0022236
Disease	metachronous colorectal adenoma	PDE4D SLC6A11 KCNA5	1.78e-03	45	157	3	EFO_0803377
Disease	economic and social preference	PLXNA4 ASCC3 ATP2B2 ATP2B4	1.82e-03	97	157	4	EFO_0004827
Disease	free cholesterol in very small VLDL measurement	TDRD15 CETP PCCB	2.02e-03	47	157	3	EFO_0022275
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	CETP MAP4K5	2.11e-03	13	157	2	OBA_2045072
Disease	MAP kinase-activated protein kinase 3 measurement	CFH NRG1	2.11e-03	13	157	2	EFO_0008226
Disease	Graves ophthalmopathy (is_marker_for)	IL18 KIF1A	2.11e-03	13	157	2	DOID:0081120 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NKVNGFTCIVQEDMP	ERICH6	461	Q7L0X2
QTMEGCSSPIVVKFA	CELF2	196	O95319
GFPSQAQVTVHCLKM	CETP	331	P11597
ADVIGKSMNQAICIP	ANAPC4	541	Q9UJX5
LMTCQPGVTAQEKVN	C8A	11	P07357
AEGTPCISKEVMCQL	CPED1	161	A4D0V7
NKVLMPCDAVLIEGS	ATP13A4	291	Q4VNC1
GSTPIGKQIMKSCAV	ALDH1L2	671	Q3SY69
PARVTIKMECNPSQV	ERG	61	P11308
TQMSKQVDCSPAGVK	BCORL1	146	Q5H9F3
KPQIIAMGNVSFSCS	CNTNAP4	351	Q9C0A0
GQSETVVICANPKGM	ACSM5	371	Q6NUN0
KTPLMTACASGNIDV	ANKEF1	526	Q9NU02
SQCKIMIPSAQQEIG	ANKRD50	1326	Q9ULJ7
KMASFQGTVTCEAPN	ATP8B3	296	O60423
ALPKAQTTVTCMENG	CFH	421	P08603
NCQGMDSVIKPLDTI	CDK14	51	O94921
KMSIQGCVAQPSSFL	CD177	366	Q8N6Q3
PGKMESQKVISCLQA	CLSTN2	526	Q9H4D0
APLGRSVEVTKMSCQ	CDHR4	561	A6H8M9
GACITQDSPLKAVQM	ATP2B2	896	Q01814
GACITQDSPLKAVQM	ATP2B4	861	P23634
GGMQVVSLAPTCLQK	ASTL	161	Q6HA08
CAMPSQVPDKQLTTI	ASTN1	1101	O14525
KMEGSTGVIIVNPNC	ASXL3	1151	Q9C0F0
MLKTIQGTDTPCIAI	ASXL3	1281	Q9C0F0
QPCIFGDKMVSIQIT	AP3B1	891	O00203
MILNPEGDVNSAKVC	RBM12	531	Q9NTZ6
IKSVLTVNPCMSNQE	RIC1	406	Q4ADV7
ICNKISEMIQGLATP	INTS7	176	Q9NVH2
APACGDVMKLQIQVD	ISCU	66	Q9H1K1
FTGARCTENVPMKVQ	NRG1	216	Q02297
MVGQVKQCEGITSPE	PPME1	231	Q9Y570
SVVTNCALIGMSPQV	ANO10	566	Q9NW15
LQVCQSSGGIPKNME	FANCI	1181	Q9NVI1
SKVCSPVSGILFNNM	GGT3P	406	A6NGU5
MNCVPDVITASKAGV	FIGN	121	Q5HY92
MPNASCGVPTLKVQV	NTRK1	186	P04629
VAPVCLKTNSQMSGS	LINS1	71	Q8NG48
DGAKMVAAVACAQVP	MCCC2	421	Q9HCC0
TAMAVCNSISNPVTK	RNGTT	541	O60942
QKLMPGSTLVLQCVA	MALT1	236	Q9UDY8
ALKVPVSEGCSQALM	GPC2	241	Q8N158
TGVKVCPQESMKQIL	IMPG1	76	Q17R60
QNVAPTLTMLCAKTG	LRFN1	41	Q9P244
SIGPSIVCKSIQMNQ	LCORL	186	Q8N3X6
MTENVVCTGAVNAVK	LRRC39	1	Q96DD0
VSLDPMKNVTCENGL	LOXL2	281	Q9Y4K0
MKNVTCENGLPAVVS	LOXL2	286	Q9Y4K0
TGTLALGVNMPCKSV	DDX60	1291	Q8IY21
LGVNMPCKSVVFAQN	DDX60	1296	Q8IY21
PTECQTGQLKRIVMS	CFAP52	196	Q8N1V2
GRMCPATQKLIEESQ	PNN	246	Q9H307
AGSNVVVMFGKQPCL	PLXNA4	981	Q9HCM2
SMPGCKKNALSQIVD	PNLIPRP1	251	P54315
PMCNQPSINKATITE	PDE4D	256	Q08499
NKIPSMQVGFIDAIC	PDE5A	811	O76074
LSAQMKAVSAECLGP	KIF21B	1141	O75037
KGARTAPLQCVSMAE	KIF21B	1291	O75037
AKVTQNLPMKEGCTE	HNRNPUL2	296	Q1KMD3
SPVSNNFMGCLKDVV	NRXN2	441	Q9P2S2
FIGNAKTCMIANISP	KIF24	511	Q5T7B8
VKCSSLAVPGKINMS	SELE	491	P16581
TPDSCIISMVVGQLK	NUTF2	76	P61970
NLAGKPVVCATQMLE	PKLR	361	P30613
NCLSDAGVRKMTAPV	LRRC42	211	Q9Y546
TPLNTSGVQVICMKG	AP2M1	326	Q96CW1
TVTCKCDLEGIMPNV	AP5M1	236	Q9H0R1
KENSSEVVQPFLMGC	MON2	61	Q7Z3U7
VPAMIKLACGDTSLN	OR2C1	181	O95371
MAEQLSPGKAVDQVC	RNF113A	1	O15541
APLCKQEGVMSVLTV	PCNT	2011	O95613
LTEGVKTSGMPEICQ	DSG1	656	Q02413
SSCQVGELVIPNLMA	NSUN4	356	Q96CB9
IGEPQDFTCKTRQTM	GPRC6A	651	Q5T6X5
ICKIMDQAITVGAPV	PCCB	141	P05166
LRVVTVCNGNTMPLA	OTOP1	461	Q7RTM1
SLQGVDPETCMIVFK	FHIP1A	16	Q05DH4
ASSGNMKVLQEPTCV	IL4R	21	P24394
ICTNMAQLVPSHVKG	EPHX1	231	P07099
CPSKAGFSRNIMNII	KCNA5	346	P22460
SGLSMKAQAISPCVQ	COG1	501	Q8WTW3
GQVAKLDLECMVPVS	BAMBI	206	Q13145
MATKSCPECDQQVPV	C16orf87	11	Q6PH81
KTQPMKVQVECSRGV	COL12A1	421	Q99715
AVEVGPKSTMVCQHV	EFCAB7	596	A8K855
IFPCKPTIQASEMSN	DCST1	441	Q5T197
EKVVNPGEQFSLMCA	DSCAML1	416	Q8TD84
LQAADTCPEVKMVGL	FCN2	26	Q15485
DVNCSVMGPQEKKVV	CTSC	51	P53634
SMLTDPGNVQKAVCH	ACE2	331	Q9BYF1
RITMICLPQTKGATN	CLPSL2	61	Q6UWE3
AGCKMPSAEQSRIAQ	MAPKBP1	1441	O60336
SQPRGMAVTISVKCE	IL18	91	Q14116
GSLSPMVITCQAVVN	C4orf54	1146	D6RIA3
IPCTSDMAKQAQVPL	SEC24C	381	P53992
DTVICAMKITQEPQG	SPACA3	176	Q8IXA5
VQVISMEPESCSPKN	GSTCD	611	Q8NEC7
SPQMKALACVSAEGV	PPRC1	1076	Q5VV67
PCVAMEIQQNNATKT	NME7	306	Q9Y5B8
MSQLVECVPNFSEGK	FTCD	1	O95954
IVNAFCQETSPEMKG	FANCD2	796	Q9BXW9
DQQAMLKTPNTFAVC	KIF1A	1631	Q12756
KTLEMNPCTPNNVEV	LIFR	896	P42702
PMVCVAISKGTESNQ	MAP4K5	686	Q9Y4K4
PCIQLSSKNEASGMV	PPP1R3B	36	Q86XI6
MDPNQNVKCKIVVVG	RND3	16	P61587
SNVMISPEVLCKEGI	JARID2	981	Q92833
DSNPMVICQLKGGTQ	TESMIN	206	Q9Y4I5
SRAACAVKPQEVQMV	IGF2R	2121	P11717
VLCGDPVMRVSLSQQ	RTTN	906	Q86VV8
IKNCFTPQTGLSDIM	MEIOC	266	A2RUB1
KGPVLCVVMSSNGEQ	STRN	516	O43815
VPLSQECVTKGAMEL	TDRD6	1876	O60522
MIPKGALAVAVAQVC	SFTPB	221	P07988
LSTPEIQKCGDMAVA	MELTF	371	P08582
IKVTPLQQMLASCTG	SLC25A40	11	Q8TBP6
TVGTQVLCPMSDSKI	TDRD15	416	B5MCY1
VMVEPGTTVLQACEK	NDUFS1	41	P28331
PGMATKSETQPQVCA	SPATA31A6	1011	Q5VVP1
LCVPAMNVNDSVTKQ	AHCYL1	271	O43865
GMATKSETQPQVCAA	SPATA31A7	1016	Q8IWB4
PDVKGAVLVCDMSSN	PSAT1	166	Q9Y617
MDVQVGETFKVPSSC	SMAD4	331	Q13485
QPQVEGVDNKMSQCT	NCOA3	756	Q9Y6Q9
PAVQSALQAMKTVCS	PREX1	221	Q8TCU6
CQGVNTGMAAEVPKV	SHISAL2A	116	Q6UWV7
CPTVKAAEMAQRLSG	SHPRH	826	Q149N8
VTQPKEEMAQRGCTK	SAPCD1	126	Q5SSQ6
TACVLTGQPFDTMKV	SLC25A15	21	Q9Y619
MKVQDIPTGADSCVT	RPTOR	1156	Q8N122
TNENMLICAPTGAGK	ASCC3	491	Q8N3C0
SMPFKLAQVVQAACG	CHST3	431	Q7LGC8
GMATKSETQPQVCAA	SPATA31A3	1016	Q5VYP0
IFVPTAQDGAQMVCK	nan	101	Q9BRP9
GSIPMQACQQKDVFA	ZCCHC8	386	Q6NZY4
SNLASVGLCVAKPEM	ZNF157	61	P51786
MNQCLVATGTHEPKN	PLAUR	241	Q03405
GMTVSKPDLIACLEQ	ZNF735	56	P0CB33
VECVASAAMISPGKL	ZSCAN30	201	Q86W11
QCEVKLLVTASMPGT	UNC80	1981	Q8N2C7
TMAGAVIAPSTKCKQ	SPEN	2761	Q96T58
GMATKSETQPQVCAA	SPATA31A1	1016	Q5TZJ5
LKTQDCLVPMVNSVA	REV1	236	Q9UBZ9
GMATKSETQPQVCAA	SPATA31A5	1016	Q5VU36
IPSQFTRVMGKVCTQ	SAMD4B	471	Q5PRF9
TAAQKAQEACGPLEM	TLN1	1036	Q9Y490
KTMLQNVSAEVCVPV	ZBTB41	796	Q5SVQ8
CSVGLMSSVVAPAKE	SLC6A3	6	Q01959
AGIAPNTMLAKVCSD	POLK	311	Q9UBT6
GCVSQMLIQKQISHP	ZNF546	191	Q86UE3
PQTMTVCQVKLSNGL	XRN1	1466	Q8IZH2
SETEAVQGNPMKLRC	SCN3B	31	Q9NY72
GVSPRMVTVNDCDAK	SLC6A11	601	P48066
DTVPVAAAMCVLKTG	SF3B3	331	Q15393
VSMVTKDNPGVVTCL	UBA1	221	P22314
QTVKLVCSVTGMALP	RBPJ	246	Q06330
MGTVAKQLVPSCVTV	VEGFB	61	P49765
EQEKSLPGVVMALVC	USP24	1066	Q9UPU5
KPSVFVMKNGTNVAC	TRDC	6	B7Z8K6
GSMVNTCQNPEIFKE	UGT3A2	301	Q3SY77
EMTNKASKEPVGCVN	ZFAND4	551	Q86XD8
LITTLQTQPGAVRCM	TG	2141	P01266
QQAIALAKEVSCPMS	TG	2431	P01266
QGQPVKLNCSVEGME	TYRO3	56	Q06418
VVPCGTEKNFTNGMV	USP32	1046	Q8NFA0
KAAEGCVMSSQPQNE	TGFBR3	216	Q03167
SAMQQGPKEFIECVS	UNC79	2396	Q9P2D8
LCTAKSPQQVMGSLV	NARF	191	Q9UHQ1
EMLCKGLSQPTSNLV	NEUROD4	156	Q9HD90
MKRVTGCILSNVNTP	NMNAT2	106	Q9BZQ4