Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycine-gated chloride ion channel activity

GLRA3 GLRA2

3.29e-0521152GO:0022852
GeneOntologyMolecularFunctionglycine binding

GLRA3 GLDC GLRA2

6.47e-05141153GO:0016594
GeneOntologyCellularComponentseptin complex

SEPTIN6 SEPTIN8 SEPTIN11

5.50e-05141143GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN6 SEPTIN8 SEPTIN11

5.50e-05141143GO:0005940
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN6 SEPTIN8 SEPTIN11

8.40e-05161143GO:0032156
DomainG_SEPTIN_dom

SEPTIN6 SEPTIN8 SEPTIN11

5.75e-05131123IPR030379
DomainSeptin

SEPTIN6 SEPTIN8 SEPTIN11

5.75e-05131123PF00735
DomainG_SEPTIN

SEPTIN6 SEPTIN8 SEPTIN11

5.75e-05131123PS51719
DomainKRAB

ZNF585A ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 ZNF436 ZNF92 ZNF84 ZNF90

5.91e-0535811210PS50805
DomainKRAB

ZNF585A ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 ZNF436 ZNF92 ZNF84 ZNF90

5.91e-0535811210PF01352
Domainzf-C2H2

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

6.86e-0569311214PF00096
DomainSeptin

SEPTIN6 SEPTIN8 SEPTIN11

7.28e-05141123IPR016491
DomainKRAB

ZNF585A ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 ZNF436 ZNF92 ZNF84 ZNF90

7.60e-0536911210SM00349
DomainKRAB

ZNF585A ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 ZNF436 ZNF92 ZNF84 ZNF90

7.77e-0537011210IPR001909
DomainGlycine_rcpt_A

GLRA3 GLRA2

2.12e-0441122IPR008127
Domain-

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

2.15e-04679112133.30.160.60
DomainZINC_FINGER_C2H2_2

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

2.21e-0477511214PS50157
DomainZINC_FINGER_C2H2_1

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

2.27e-0477711214PS00028
DomainZnf_C2H2/integrase_DNA-bd

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

2.66e-0469411213IPR013087
DomainZnf_C2H2

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

3.26e-0480511214IPR007087
DomainZnF_C2H2

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

3.38e-0480811214SM00355
DomainFATC

ATR MTOR

3.52e-0451122PF02260
DomainFAT

ATR MTOR

5.26e-0461122PS51189
DomainFATC

ATR MTOR

5.26e-0461122PS51190
DomainFAT

ATR MTOR

5.26e-0461122PF02259
DomainPIK-rel_kinase_FAT

ATR MTOR

5.26e-0461122IPR003151
DomainFATC_dom

ATR MTOR

5.26e-0461122IPR003152
DomainPIK_FAT

ATR MTOR

5.26e-0461122IPR014009
DomainFATC

ATR MTOR

5.26e-0461122SM01343
DomainZnf_MYM

ZMYM4 ZMYM6

7.34e-0471122IPR010507
Domainzf-FCS

ZMYM4 ZMYM6

7.34e-0471122PF06467
DomainZnf_C2H2-like

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

9.63e-0479611213IPR015880
DomainTRASH_dom

ZMYM4 ZMYM6

9.75e-0481122IPR011017
DomainTRASH

ZMYM4 ZMYM6

9.75e-0481122SM00746
DomainEPL1

JADE1 EPC1

9.75e-0481122PF10513
DomainEnhancer_polycomb-like_N

JADE1 EPC1

9.75e-0481122IPR019542
DomainMyosin_head_motor_dom

MYO1D MYO10 MYO18B

1.52e-03381123IPR001609
DomainMYOSIN_MOTOR

MYO1D MYO10 MYO18B

1.52e-03381123PS51456
DomainMyosin_head

MYO1D MYO10 MYO18B

1.52e-03381123PF00063
DomainMYSc

MYO1D MYO10 MYO18B

1.52e-03381123SM00242
Domainzf-C2H2_6

FEZF2 ZNF195 ZNF621 GFI1 ZNF92 ZNF84 ZNF90

2.86e-033141127PF13912
DomainPI3/4_kinase_CS

ATR MTOR

3.56e-03151122IPR018936
Domain-

ATR MTOR

4.05e-031611221.10.1070.11
DomainPI3Kc

ATR MTOR

4.05e-03161122SM00146
DomainHEAT

ATR TOGARAM1 MTOR

5.10e-03581123IPR000357
DomainPI3_PI4_kinase

ATR MTOR

5.12e-03181122PF00454
DomainPI3_4_KINASE_1

ATR MTOR

5.12e-03181122PS00915
DomainPI3_4_KINASE_2

ATR MTOR

5.12e-03181122PS00916
DomainPI3/4_kinase_cat_dom

ATR MTOR

5.12e-03181122IPR000403
DomainPI3_4_KINASE_3

ATR MTOR

5.12e-03181122PS50290
Pubmed

SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.

RELN CRIM1 FEZF2 DIAPH3

1.56e-0715116418215621
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF254 ZNF195 ZNF595

2.99e-069116310360839
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN6 SEPTIN8 SEPTIN11

2.99e-069116318809578
Pubmed

Cyclooxygenase-2 up-regulates ataxia telangiectasia and Rad3 related through extracellular signal-regulated kinase activation.

ATR PTGS2

1.10e-052116219584262
Pubmed

Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.

GLRA3 GLRA2

1.10e-052116227382060
Pubmed

Inhibition of mammalian target of rapamycin signaling pathway decreases retinoic acid stimulated gene 8 expression in adult mouse testis.

STRA8 MTOR

1.10e-052116225241363
Pubmed

mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.

MTOR PHLPP1

1.10e-052116221177869
Pubmed

Selective glycine receptor α2 subunit control of crossover inhibition between the on and off retinal pathways.

GLRA3 GLRA2

1.10e-052116222399754
Pubmed

ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.

ATR FANCM

1.10e-052116223698467
Pubmed

Mannan and peptidoglycan induce COX-2 protein in human PMN via the mammalian target of rapamycin.

PTGS2 MTOR

1.10e-052116217683115
Pubmed

Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.

ATR REV3L

1.10e-052116228075014
Pubmed

MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.

MTOR MYO18B

1.10e-052116230390677
Pubmed

Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain.

GLRA3 GLRA2

1.10e-052116228784756
Pubmed

Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.

CRIM1 FEZF2 DIAPH3

1.28e-0514116315664173
Pubmed

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.

ATR FANCM FANCI

1.60e-0515116319536649
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN6 SEPTIN8 SEPTIN11

1.96e-0516116322575789
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

AHCYL1 PDE2A FAM120B MYO1D COPS3 PTGS2 OPCML SEPTIN6 CSDE1 SEPTIN8 ATP6V1H MICAL2 SEPTIN11 ATP1A2 TNS1 VDAC1

2.23e-0514311161637142655
Pubmed

Fezl is required for the birth and specification of corticospinal motor neurons.

CRIM1 FEZF2 DIAPH3

2.38e-0517116316157277
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

AHCYL1 DTNA SEC24A SMC2 CSDE1 ATP6V1H CCDC88A FANCI DIAPH3 SLC25A19 VDAC1

2.62e-057081161139231216
Pubmed

The granulocyte-colony stimulating factor receptor (G-CSFR) interacts with retinoic acid receptors (RARs) in the regulation of myeloid differentiation.

RARA CSF3R

3.30e-053116223136256
Pubmed

The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling.

RARA PRAME

3.30e-053116216179254
Pubmed

The interleukin 6 trans-signaling increases prostaglandin E2 production in human granulosa cells†.

PTGS2 IL6R

3.30e-053116234198336
Pubmed

Cloning and mapping of members of the MYM family.

ZMYM4 ZMYM6

3.30e-053116210486218
Pubmed

F-actin rearrangement is regulated by mTORC2/Akt/Girdin in mouse fertilized eggs.

CCDC88A MTOR

3.30e-053116227666957
Pubmed

Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2.

ATR FANCM

3.30e-053116231067464
Pubmed

Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5.

SEPTIN8 SEPTIN11

3.30e-053116216767699
Pubmed

Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation.

PTGS2 ARNT

3.30e-053116229568008
Pubmed

Interleukin 6 receptor alpha expression in PMNs isolated from prematurely born neonates: decreased expression is associated with differential mTOR signaling.

MTOR IL6R

3.30e-053116230965356
Pubmed

Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice.

GLRA3 GLRA2

3.30e-053116217920294
Pubmed

Septin expression in proliferative retinal membranes.

SEPTIN8 SEPTIN11

3.30e-053116217625225
Pubmed

The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation.

ATR KIFC1

3.30e-053116233397932
Pubmed

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.

MTOR VDAC1

3.30e-053116226655341
Pubmed

Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination.

ATR FANCI

3.30e-053116234828369
Pubmed

Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein.

RARA STRA8

3.30e-05311629203140
Pubmed

Direct control of mitochondrial function by mTOR.

MTOR VDAC1

3.30e-053116220080789
Pubmed

Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).

MTOR IL6R

3.30e-053116224047696
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF195 ZNF595 ZNF92 ZNF724 ZNF84 ZNF90

3.38e-05181116637372979
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

AHCYL1 MYO10 INTS1 TRMT1 JADE1 GFI1 ARNT SUDS3 EPC1 CDK5RAP1 PHLPP1 DIAPH3 NXF1 ZMYM4 VDAC1

3.64e-0513271161532694731
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF254 ZNF195 ZNF595

3.95e-052011637479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF254 ZNF195 ZNF595

3.95e-052011632542606
Pubmed

Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.

ZNF254 ZNF195 ZNF595 CSF3R

5.29e-056111648662221
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

AHCYL1 OPCML SEPTIN6 SEPTIN8 ATP6V1H SEPTIN11 ATP1A2 VDAC1

6.48e-05403116830562941
Pubmed

Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.

GLRA3 GLRA2

6.59e-05411629051263
Pubmed

CCR5-Dependent Activation of mTORC1 Regulates Translation of Inducible NO Synthase and COX-2 during Encephalomyocarditis Virus Infection.

PTGS2 MTOR

6.59e-054116226408666
Pubmed

Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.

ATR MTOR

6.59e-054116219955088
Pubmed

Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma.

PTGS2 ARNT

6.59e-054116219203995
Pubmed

Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting.

CRIM1 FEZF2

6.59e-054116234686320
Pubmed

Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process.

PTGS2 CSF3R

6.59e-054116223337807
Pubmed

Glycinergic input of widefield, displaced amacrine cells of the mouse retina.

GLRA3 GLRA2

6.59e-054116219528249
Pubmed

Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.

GLRA3 GLRA2

6.59e-054116221486797
Pubmed

Fine mapping of the human pentraxin gene region on chromosome 1q23.

PTGS2 FCER1A

6.59e-05411628613143
Pubmed

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

ATR FANCI

6.59e-054116218931676
Pubmed

Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition.

FANCM FANCI

6.59e-054116219737859
Pubmed

Human transcription factor protein interaction networks.

AHCYL1 MYO1D DTNA SEC24A ZNF691 SEPTIN6 ARNT SUDS3 EPC1 ZNF724 HERC1 NXF1 ZMYM4 VDAC1 KIFC1

8.37e-0514291161535140242
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AHCYL1 RELN PDE2A CRIM1 FEZF2 REV3L SMYD2 CSDE1 MICAL2 ZNF92 ZNF84 ATP1A2 ZMYM4 DOP1B

9.95e-0512851161435914814
Pubmed

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

ATR MTOR EXOC2

9.97e-0527116323027611
Pubmed

Septins regulate bacterial entry into host cells.

SEPTIN6 SEPTIN11

1.10e-045116219145258
Pubmed

Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.

GLRA3 GLRA2

1.10e-045116221850450
Pubmed

Native glycine receptor subtypes and their physiological roles.

GLRA3 GLRA2

1.10e-045116218721822
Pubmed

ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

ATR FANCI

1.10e-045116225843623
Pubmed

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.

SEPTIN6 SEPTIN11

1.10e-045116224113571
Pubmed

Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations.

CRIM1 FEZF2

1.10e-045116236934325
Pubmed

Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice.

ARNT IL6R

1.10e-045116211937300
Pubmed

Pyramidal neuron subtype diversity governs microglia states in the neocortex.

RELN FEZF2

1.10e-045116235948630
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF254 ZNF595

1.10e-045116224190968
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF254 ZNF595

1.10e-045116220042539
Pubmed

mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.

LAMP1 MTOR

1.10e-045116223394946
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF254 ZNF195 ZNF595

1.24e-0429116314563677
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYO1D SEC24A TRMT1 CHML PIGU SENP1 STX5 PMPCA ARFGAP3 CDK5RAP1 PNPLA8 DIAPH3 HERC1 PRAME VDAC1

1.39e-0414961161532877691
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

INTS1 REV3L SMC2 ZMYM4 VDAC1

1.52e-04150116530154076
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MYO1D DTNA ARNT CCDC88A ZNF92 DIAPH3 NXF1 ZMYM4 ZMYM6

1.63e-04588116938580884
Pubmed

FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.

ATR FANCM

1.64e-046116218995830
Pubmed

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.

ARNT MTOR

1.64e-046116223183047
Pubmed

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway.

ATR FANCI

1.64e-046116222258451
Pubmed

FANCI is a negative regulator of Akt activation.

FANCI PHLPP1

1.64e-046116227097374
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF254 ZNF595

1.64e-046116230846446
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

AHCYL1 CRIM1 ATR INTS1 PIGU CSDE1 SEPTIN8 STX5 PMPCA FANCI SEPTIN11 HERC1

2.29e-0410611161233845483
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF254 ZNF595

2.29e-047116222801370
Pubmed

Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth.

RELN MTOR

2.29e-047116217698586
Pubmed

Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically toward Thoraco-Lumbar Spinal Cord.

CRIM1 FEZF2

2.29e-047116236823038
Pubmed

Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.

GLRA3 GLRA2

2.29e-047116222988142
Pubmed

Lysosomal dynamics regulate mammalian cortical neurogenesis.

LAMP1 MTOR

2.29e-047116238103552
Pubmed

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.

FANCM FANCI

2.29e-047116224451376
Pubmed

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

AHCYL1 FBXL2 PRAME

2.38e-0436116324035498
Pubmed

Septin 14 is involved in cortical neuronal migration via interaction with Septin 4.

SEPTIN6 SEPTIN11

3.05e-048116220181826
Pubmed

Identifying key genes related to inflammasome in severe COVID-19 patients based on a joint model with random forest and artificial neural network.

PTGS2 MTOR

3.05e-048116237113134
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF92 ZNF90

3.05e-04811622023909
Pubmed

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

ATR MTOR

3.05e-048116220810650
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

AHCYL1 ATR SMC2 CSDE1 ARNT CCDC88A CDK5RAP1 NXF1 KIFC1

3.40e-04650116938777146
Pubmed

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.

TRMT1 SEPTIN6 CSDE1 SEPTIN8 SEPTIN11

3.54e-04180116530110629
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYO1D MYO10 MICAL2 ATP1A2

3.74e-0410111649872452
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

JADE1 SUDS3 EPC1

3.77e-0442116316387653
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

ATR SMC2 ATP6V1H MTOR DOP1B

3.82e-04183116523956138
Pubmed

The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs.

COPS3 PTGS2

3.91e-049116217429597
Pubmed

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.

LAMP1 MTOR

3.91e-049116228137967
Pubmed

A 6000 kb segment of chromosome 1 is conserved in human and mouse.

FCER1A ATP1A2

3.91e-04911622591369
Pubmed

Retinoid signaling determines germ cell fate in mice.

RARA STRA8

3.91e-049116216574820
Pubmed

FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

RELN FBXO10

3.91e-049116220554749
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

RARA STRA8

3.91e-049116228235998
Pubmed

Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1.

FCER1A ATP1A2

3.91e-04911627797269
InteractionFGFR1 interactions

AHCYL1 RARA DTNA SEC24A SMC2 OPCML SEPTIN6 SEPTIN8 CCDC88A STX5 ARFGAP3 FANCI SEPTIN11 IL17RD VDAC1

2.50e-0663211315int:FGFR1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF138 ZNF585A FEZF2 ZNF175 ZNF254 ZNF195 ZNF621 ZNF595 GFI1 ZNF691 ZNF436 ZNF92 ZNF84 ZNF90

7.87e-06718871428
GeneFamilySeptins

SEPTIN6 SEPTIN8 SEPTIN11

2.97e-0513873732
GeneFamilyGlycine receptors

GLRA3 GLRA2

2.27e-045872868
GeneFamilyZinc fingers MYM-type

ZMYM4 ZMYM6

3.39e-04687286
GeneFamilyX-linked mental retardation|RNA helicases

FANCM HFM1

1.22e-03118721168
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

FANCM FANCI

4.11e-0320872548
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

SMC2 FCER1A FANCI HFM1 DIAPH3 ATP1A2 KIFC1

5.67e-0718511679d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OPCML GLRA2 MYO18B PRAME UBALD1

4.07e-06911165b0658e020f80e56fab9d2aa07e321d9b33d7af2c
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

ATP8B3 CLEC5A PTGS2 CC2D2B FCER1A CSF3R

6.20e-06173116638f88f5bbf92a3bf5109bc4782cd071b7cb1ca34
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLEC9A DTNA PTGS2 CCDC88A CSF3R NALCN

1.03e-051891166e4b2f00cb3675a4d94e8807d6ff99cc55f9ed233
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

CLEC9A DTNA CLEC5A FCER1A CSF3R ALPK3

1.16e-051931166198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SMC2 OPCML FANCI ZNF724 DIAPH3 KIFC1

1.16e-051931166bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1|TCGA-Endometrium / Sample_Type by Project: Shred V9

SMC2 PTGS2 SMYD2 FANCI DIAPH3 IL17RD

1.16e-051931166c2673d86f7d7b849788036032a93a6d136a70040
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CLEC9A DTNA CCDC88A FCER1A IL6R VDAC1

1.16e-051931166984ea5b871479527ab57dd813bacae844c0d8c06
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CLEC9A DTNA CCDC88A FCER1A IL6R VDAC1

1.16e-051931166529281b912070c8655e38880ac73f5e4bd6ee4ce
ToppCellILEUM-inflamed-(3)_moDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CLEC9A CHML PTGS2 CCDC88A FCER1A CSF3R

1.19e-051941166c9d2acab0bbcfa9a9113cf3b9f8147403f0beb43
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 MYO1D DTNA MICAL2 ATP1A2 MYO18B

1.19e-0519411665c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 MYO1D DTNA MICAL2 ATP1A2 MYO18B

1.19e-051941166ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|343B / Donor, Lineage, Cell class and subclass (all cells)

CLEC5A SMC2 FCER1A FANCI DIAPH3 KIFC1

1.23e-05195116647a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

RELN PDE2A CRIM1 MYO10 ADGRL4 HERC1

1.26e-051961166e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell343B-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A CLEC5A COPS3 SEPTIN6 FCER1A KIFC1

1.30e-051971166b340d6f041231e5c69140895aaa1e8d28bafb998
ToppCellmild-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLEC5A SMC2 GFI1 FANCI DIAPH3 KIFC1

1.30e-051971166bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell(3)_DC_Monocyte_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CLEC5A SMC2 FCER1A FANCI DIAPH3 KIFC1

1.34e-051981166e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCellsevere-Myeloid-Immature_Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLEC5A SMC2 GFI1 FANCI DIAPH3 KIFC1

1.34e-051981166844f534551483c89ef789d1cfeb4680e54f794b2
ToppCellsevere-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLEC5A SMC2 GFI1 FANCI DIAPH3 KIFC1

1.34e-051981166e36303628af3139310c1d7a84d2919b7319bbda4
ToppCell(5)_Dendritic_cell|World / shred on Cell_type and subtype

CLEC9A PTGS2 CCDC88A FCER1A CSF3R DIAPH3

1.38e-051991166495de74a918c5c625a2d0ef120fe4162d4ce6e76
ToppCellMild/Remission-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SMC2 GLDC FANCI DIAPH3 IL6R KIFC1

1.38e-0519911661dda6116de639140c2d6f5012b7ab9ad0f737ae1
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZNF195 SMC2 CCDC88A FANCI DIAPH3 KIFC1

1.41e-0520011664cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell(52)_cycling_DCs|World / shred on Cell_type and subtype

CLEC9A CLEC5A PTGS2 FCER1A DIAPH3 KIFC1

1.46e-052011166ad2d25d84345fdd593065516a05c5c2b5429eac0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRIM1 FEZF2 NSUN7 LRRC9 DIAPH3

2.58e-0513311659d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

DSG3 PNLDC1 NALCN SEPTIN11 FBXL2

3.41e-051411165399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

CLEC9A DTNA FCER1A ALPK3 CD200R1L

5.70e-051571165ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A SEPTIN6 CCDC88A DIAPH3 IL6R

6.23e-0516011655c28121916a12dbc22ef2421040bdc9148a40b78
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A SEPTIN6 CCDC88A DIAPH3 IL6R

6.23e-051601165b7093678987575f2f99d648821d31b4a37075aca
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHML GFI1 FBXL2 ZMYM4 ARAP2

6.81e-051631165a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC9A SEPTIN6 CCDC88A ZNF724 KIFC1

7.42e-05166116563dc58864268b4e7779e4c45155022556fc634f9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A PARS2 MTOR EPC1 SLC25A19

9.51e-051751165bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE2A COPS3 NAGS CCDC88A FCER1A

9.51e-051751165c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PDE2A NALCN MICAL2 PRAME

1.00e-041771165c274fbdc141855ff4581d437d4997c64cc193278
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PDE2A NALCN MICAL2 PRAME

1.00e-041771165f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A ADAM32 SMC2 DIAPH3 KIFC1

1.00e-041771165844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A ADAM32 SMC2 DIAPH3 KIFC1

1.00e-04177116526c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PDE2A NALCN MICAL2 PRAME

1.00e-041771165c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho|lymph-node_spleen / Manually curated celltypes from each tissue

ZNF175 SI PIGU ZNF691 FCER1A

1.00e-04177116553040dbeb18574a48e352e4bce252c7c3018762c
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A SMC2 FANCI DIAPH3 KIFC1

1.00e-041771165ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A CRIM1 MYO10 STRA8 ADGRL4

1.03e-041781165a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RELN PDE2A ADGRL4 NALCN MICAL2

1.06e-041791165ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RELN PDE2A ADGRL4 NALCN MICAL2

1.06e-04179116535fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GLDC FANCI DIAPH3 IL6R KIFC1

1.06e-0417911659383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTNA SEPTIN6 LRFN2 ATP1A2 ARAP2

1.09e-04180116578fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SMC2 FANCI DIAPH3 CD200R1L KIFC1

1.11e-041811165ac1ee313910c05b1b3cb497bae14565464919c21
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN CRIM1 DTNA LRFN2 NALCN

1.11e-0418111655f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN CRIM1 DTNA LRFN2 NALCN

1.11e-041811165c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PTGS2 FCER1A HFM1 DIAPH3 KIFC1

1.17e-041831165f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

MYO1D SEC24A SEPTIN6 GLDC DIAPH3

1.17e-0418311652c016bb59f131a0e821853b085289a3583f0a729
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D MICAL2 DIAPH3 TNS1 ARAP2

1.20e-04184116557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SMC2 FANCI ZNF724 DIAPH3 KIFC1

1.20e-0418411656b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SMC2 FANCI ZNF724 DIAPH3 KIFC1

1.20e-041841165e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D MICAL2 DIAPH3 TNS1 ARAP2

1.20e-041841165d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DTNA SMYD2 NALCN ALPK3 MYO18B

1.20e-041841165e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC5A REV3L CHML SLC25A19 IL6R

1.20e-041841165b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PNLDC1 SMC2 FANCM DIAPH3 KIFC1

1.23e-0418511650e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PNLDC1 SMC2 FANCM DIAPH3 KIFC1

1.23e-04185116589b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCellnormal-na-Myeloid-conventional_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CLEC9A CCDC88A FCER1A IL6R VDAC1

1.23e-04185116567e881a89a491665b8c612fff084c202c0c79235
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLRA3 PTGS2 CSF3R PNPLA8 IL6R

1.23e-04185116542690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

CLEC9A GPR88 CCDC88A DIAPH3 KIFC1

1.23e-041851165912d8efdc37820dbb07736221a98af929e5a7c97
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP8B3 SMC2 FANCI DIAPH3 KIFC1

1.23e-0418511659d424a8608b339dd6129c58d87626678d4ec4af7
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

MYO1D SEC24A SEPTIN6 GLDC DIAPH3

1.27e-04186116566676d9395172de5707e204826a1c9f73b448cca
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

CLEC9A SI CCDC88A FCER1A IL6R

1.27e-04186116563a5cdd3f60681762a218be32db84be8f29b88fd
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

CLEC9A SI CCDC88A FCER1A IL6R

1.27e-04186116539457a7b43537f2c3e221f9375c95d4515424d7d
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ATP8B3 SMC2 FANCI DIAPH3 KIFC1

1.27e-0418611650067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellHealthy-multiplets|Healthy / disease group, cell group and cell class

CLEC9A MYO1D GLDC DIAPH3 KIFC1

1.27e-0418611652ec999b97e95afb898f8083042b0f188d3d234bc
ToppCelldroplet-Fat-SCAT-30m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.33e-041881165e901a9bdf00b8e91806f445af66647373bf62661
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO1D PTGS2 MICAL2 FBXL2 ARAP2

1.33e-04188116543a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.33e-0418811655cf060bb8adaefa9964187195d67993c1248ef47
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.33e-041881165449f9602df3c83b2110eb479a00d428d1b55b423
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-041901165d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CLEC9A CCDC88A FCER1A IL6R VDAC1

1.40e-0419011654b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-04190116538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-041901165dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellMonocytes-Tissue-resident_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

CLEC9A DTNA CLEC5A FCER1A CSF3R

1.40e-04190116507215e8f292cb54c670037aaf28393cddbe5548c
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-041901165c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCell(2)_Dendritic_Cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CLEC9A CLEC5A PTGS2 FCER1A CSF3R

1.40e-0419011655163a5be95fb6c2609bfa3d69166af172f74e724
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-0419011655174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-041901165bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-041901165d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.40e-04190116590e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

SMC2 CCDC88A FCER1A DIAPH3 KIFC1

1.43e-041911165aa9c0b1b90cdb7a95d4e6332819f82cae0a79ff9
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYO1D SEC24A GLDC ARFGAP3 IL6R

1.43e-0419111653df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellwk_20-22-Hematologic-Myeloid-Cycling_DC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ATP8B3 SMC2 FCER1A DIAPH3 KIFC1

1.43e-0419111651da569ebcfab4e1a95315430ae77a17a1f119263
ToppCelldroplet-Fat-Gat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.47e-041921165c312e39003c51503c9f648332fb5c6218f33f99b
ToppCelldroplet-Fat-Gat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.47e-041921165df09056f0e562f53b6fb30b674d2d83e9eb857d0
ToppCelldroplet-Fat-Gat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.47e-041921165133b3ad251d72ff31e45e1dc6217945516ac63de
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN SMYD2 CCDC88A MICAL2 TNS1

1.47e-041921165d43caf42ec744e895137f31ef65a990e250669d2
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CLEC9A CCDC88A FCER1A IL6R VDAC1

1.47e-0419211658e606eae3e5b07a856d3c2a74186d486da96309c
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLEC5A GFI1 FANCI DIAPH3 KIFC1

1.50e-04193116533349830e9eba506470ad3661fad5e5a283d20ca
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CRIM1 MYO1D MYO10 DTNA NALCN

1.50e-0419311655896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SMC2 OPCML FANCI DIAPH3 KIFC1

1.50e-041931165516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellFetal_brain-fetalBrain_Zhong_nature|Fetal_brain / Sample Type, Dataset, Time_group, and Cell type.

DSG3 JADE1 SEPTIN6 SEPTIN11 ZNF84

1.50e-0419311651553c856f3b71c1b0a78ec8d59c7948144d9c5bb
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF195 IGSF5 ZNF621 COPS3 ZNF691

1.50e-041931165088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATP8B3 CCDC88A FANCI DIAPH3 KIFC1

1.54e-041941165e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO1D SMC2 GLDC DIAPH3 KIFC1

1.54e-0419411655a519538327029ad2b880ef9647e2ac6ab3961a4
ToppCelldroplet-Fat-Scat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.54e-0419411650f81df418166589ea327d6dfe06674bcf2fe8f72
ToppCelldroplet-Fat-Scat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.54e-041941165009b005a94a5c80f6e1fdda2a0c7881a9a0ce75b
ToppCelldroplet-Fat-Scat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CRIM1 MYO10 ADGRL4 TNS1

1.54e-04194116584bfe5e68069824370dc2a3f2c5958c552eaaa03
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

DTNA SMYD2 NALCN ALPK3 MYO18B

1.58e-041951165f1ef50331eda8f1239dba6ea970df4eaccf032f1
DiseaseLarge cell carcinoma of lung

ATR MTOR ALPK3 MYO18B

6.75e-06321134C0345958
Diseaseglomerular filtration rate, renal transplant outcome measurement

GLRA3 OR1D4 MICAL2 OR1D5

9.74e-06351134EFO_0005199, EFO_0005208
Diseasesevere congenital neutropenia (implicated_via_orthology)

GFI1 CSF3R

4.35e-0531132DOID:0050590 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (is_marker_for)

GFI1 CSF3R PRAME

5.94e-05201133DOID:0050908 (is_marker_for)
Diseaseglioblastoma (biomarker_via_orthology)

PTGS2 ADGRL4

8.68e-0541132DOID:3068 (biomarker_via_orthology)
Diseaserheumatoid arthritis

PDE2A PTGS2 GFI1 SENP1 EXOC2 CD200R1L IL6R VDAC1

4.15e-044621138EFO_0000685
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

PTGS2 GFI1 EXOC2 CD200R1L IL6R

5.09e-041701135EFO_0000685, EFO_0007791, EFO_0007837
DiseaseMalignant Head and Neck Neoplasm

FANCM FANCI PRAME

6.46e-04441133C0278996
Diseaseniacinamide measurement

SEPTIN8 EXOC2

9.36e-04121132EFO_0010511
DiseaseCongenital neutropenia

GFI1 CSF3R

9.36e-04121132C0340970
DiseaseSarcomatoid Renal Cell Carcinoma

PTGS2 MTOR PRAME IL6R

1.51e-031281134C1266043
DiseaseChromophobe Renal Cell Carcinoma

PTGS2 MTOR PRAME IL6R

1.51e-031281134C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PTGS2 MTOR PRAME IL6R

1.51e-031281134C1266044
DiseasePapillary Renal Cell Carcinoma

PTGS2 MTOR PRAME IL6R

1.51e-031281134C1306837
DiseaseRenal Cell Carcinoma

PTGS2 MTOR PRAME IL6R

1.51e-031281134C0007134
DiseaseGlobal developmental delay

INTS1 TRMT1 PIGU CSDE1

1.74e-031331134C0557874
DiseaseBone marrow hypocellularity

FANCM FANCI

2.14e-03181132C1855710
DiseaseMYELODYSPLASTIC SYNDROME

FANCM CSF3R FANCI

2.19e-03671133C3463824
Diseaseportal hypertension (implicated_via_orthology)

PTGS2 MTOR

2.38e-03191132DOID:10762 (implicated_via_orthology)
Diseasebipolar disorder (is_marker_for)

RELN PTGS2

2.38e-03191132DOID:3312 (is_marker_for)
Diseaseemphysema pattern measurement

MYO1D SEPTIN11

2.38e-03191132EFO_0005850
Diseaseanorexia nervosa

MYO1D OPCML ADGRL4

2.48e-03701133MONDO_0005351
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PTGS2 MTOR PRAME IL6R

2.56e-031481134C0279702
Diseasestatus epilepticus (implicated_via_orthology)

PTGS2 MTOR

2.91e-03211132DOID:1824 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ACFSAKVNNSSLIGL

VDAC1

231

P21796
INTNTNKLFCSIIAG

ADGRL4

481

Q9HBW9
GFSAQQVATQATAKT

ARNT

646

P27540
NCFTKGQKNSTLIFT

C21orf62

21

Q9NYP8
SSALKLAAAANCQVS

EPC1

786

Q9H2F5
IFKGENVTLTCNGNN

FCER1A

41

P12319
SLGAQKLANTCFNEI

ARFGAP3

231

Q9NP61
TLFSQVQLFISTCNG

COPS3

76

Q9UNS2
VANNSISCNRQSGVK

FBXO10

771

Q9UK96
IYQASAQNSKGIVSC

ALPK3

351

Q96L96
STNCSRLQNKVSGKF

ABITRAM

71

Q9NX38
SVKFQLCVLGQNAQT

CSDE1

651

O75534
SFQNFISNVGVKCLQ

ADAM32

366

Q8TC27
LVFSSCLFQTKGQTS

ARAP2

1266

Q8WZ64
KTGTLTQNILTFNKC

ATP8B3

496

O60423
CQVAKSNSQTNGLNF

CCDC180

1131

Q9P1Z9
NAQTFGFNLSSLCKL

DIAPH3

856

Q9NSV4
KCFSLGVNLQNVAES

CC2D2B

121

Q6DHV5
CTTIDGLNATKNFLQ

CHML

351

P26374
GNIISGDKTISFNNC

OR6C1

81

Q96RD1
ALCQLGKYTTNNSSE

RARA

201

P10276
NVTCNIFINSFGSIA

GLRA3

71

O75311
NLSGNQICSFKELTN

LRRC9

171

Q6ZRR7
QQTGFVKCQTLSGSQ

DSG3

891

P32926
NFKVLGSLSSSQCSQ

FANCI

546

Q9NVI1
QSTSIGIKNNICAFL

FANCI

731

Q9NVI1
VGDSSLKTFAQNCRN

FBXL2

91

Q9UKC9
KLQTTSNAFIVNGCA

GPR88

61

Q9GZN0
FFTVNACLNGSQLAV

IL17RD

11

Q8NFM7
QVCGKAFSQSSNLIT

GFI1

371

Q99684
FKAKGNSLVSVLACN

INTS1

196

Q8N201
NFASKNIFGVQLTAS

DOP1B

636

Q9Y3R5
SFIKNINQGSSSSVI

FANCM

816

Q8IYD8
QNCTFVIQANGTVLA

HERC1

4036

Q15751
FASKVNQCVIGTAQA

KIFC1

656

Q9BW19
TVNSSAGFRSKQLVN

CCDC88A

1541

Q3V6T2
FQSRNITAVCKAVTG

CD200R1L

151

Q6Q8B3
QCVSSFSKNGALQAR

EXOC2

841

Q96KP1
QTSTLLCFSVNGVFK

NXF1

486

Q9UBU9
RGTNNSFQVASKSVL

PDE2A

701

O00408
NNSSRFGKFVQLNIC

MYO10

216

Q9HD67
NTASIQSLICNNVKG

PTGS2

546

P35354
EVLKCQQGVSSLAFA

NAGS

146

Q8N159
AKSTCAINNTLIAFF

PIGU

156

Q9H490
LQFKLNIGCANQFSS

RELN

1301

P78509
LVFCATRKGVQQAAS

HFM1

531

A2PYH4
CVATNKLGNTNASIT

OPCML

296

Q14982
LTQNKFITYAGCLSQ

OR7C1

86

O76099
CNRAVFKAGQENISV

ATP1A2

426

P50993
VTVLLKGCQDANSQA

ATR

1336

Q13535
LKGSQARFNCTVSQG

IGSF5

51

Q9NSI5
KFSKTQTFQGCGILQ

IL6R

201

P08887
SLNNQLVSVDCKKGT

CRIM1

981

Q9NZV1
FTLKSFKSRGNCQTQ

CSF3R

156

Q99062
VNVTCNIFINSFGSV

GLRA2

71

P23416
SCFSQQKKVTLNGFL

DTNA

196

Q9Y4J8
RALQATVGNSYKCNA

LAMP1

326

P11279
LIICLVNNKGSANSS

DYNAP

131

Q8N1N2
AFIAQALCLQGKSTS

FAM120B

741

Q96EK7
NQCGKAFNRSSTLNT

FEZF2

336

Q8TBJ5
QASTCKGTLQAFNIL

MICAL2

21

O94851
LAKNKSISFIGCATQ

OR5T3

116

Q8NGG3
SGQNKTQGFRKAISC

PHYH

266

O14832
QSQNKAISYAGCLTQ

OR1D4

86

P47884
QSQNKAISYAGCLTQ

OR1D5

86

P58170
LSSQKTIIFSGCAVQ

OR2K2

86

Q8NGT1
SSNVSVLQQFASGLK

MTOR

16

P42345
STLNSVSKAVFGNQN

PNPLA8

106

Q9NP80
FNAQFTNVCGKPTLA

PARS2

321

Q7L3T8
LRVASQNKFGQFCTV

PMPCA

76

Q10713
KASASKQALVFQCVG

TRMT1

336

Q9NXH9
LQTEGSQCAKTFINL

ATP6V1H

66

Q9UI12
LVNKSTSQGFCFNIL

SEPTIN11

31

Q9NVA2
AQFTSQFLSLQCLQA

PRAME

286

P78395
QTNSKGSSNFCVKNI

AHCYL1

96

O43865
VGKNCTQNFLSQVLG

SEC24A

996

O95486
SILTNNNTSKVFVCG

NSUN7

311

Q8NE18
QQFTVCQIGLSVFSA

PNLDC1

51

Q8NA58
KDSLFKNGNSCASQI

SENP1

231

Q9P0U3
SFIQGSTKGCNVNKL

SI

511

P14410
CNGSLIKVNYNQTAV

JADE1

721

Q6IE81
QLVNKSVSQGFCFNI

SEPTIN6

31

Q14141
SACKSLQTRQNGIQT

STX5

66

Q13190
GLSCANTQVKQEASF

STRA8

296

Q7Z7C7
AKNQAVAQSSGSYLC

B3GNTL1

96

Q67FW5
NQNFNCATIGLTKTF

CLEC5A

156

Q9NY25
SANQVCGYVKSNSLL

CLEC9A

206

Q6UXN8
TKANQTSVGCTQLVL

CDK5RAP1

511

Q96SZ6
QKGVNNGVYQCLSTT

ZNF595

126

Q8IYB9
NGVYQCLSTTQSKIF

ZNF595

131

Q8IYB9
NGLNQCLTTTDSKIF

ZNF92

131

Q03936
VQCGKGFTQSSNLIT

ZNF436

421

Q9C0F3
NGFNQCLTTTQSKIF

ZNF724

131

A8MTY0
ICAQCGKTFNNTSNL

ZNF691

116

Q5VV52
GFNGLNQCLKITTSK

ZNF138

66

P52744
INAQQKLSGCFSSFL

REV3L

1286

O60673
ANSTADLLKQGAACN

TNS1

1586

Q9HBL0
SKSVTQGFSFNILCV

SEPTIN8

36

Q92599
STVARFTQCQNGKIS

SMC2

1166

O95347
SNCGKSFISKSQLQV

ZNF585A

301

Q6P3V2
VSQSIVLFQAACKGF

MYO18B

1336

Q8IUG5
SQCGKAFSQKSQLTS

ZNF84

266

P51523
CGKAFTQKIASIQHQ

ZNF621

296

Q6ZSS3
NGLNQCLTATQSKVF

ZNF90

131

Q03938
QGTLTTFFNLCNKID

ZMYM6

1131

O95789
FTLTSANVGKCQTVL

PHLPP1

1281

O60346
QTNLSGKCAQLGFSQ

TOGARAM1

741

Q9Y4F4
DNQKLSCVISSVGAN

SUDS3

281

Q9H7L9
SLVVLFAQVNCNGFT

SMYD2

171

Q9NRG4
RNNTKFQVAVAGSVS

SLC25A19

11

Q9HC21
NTNSLGKTELFCSVN

ZMYM4

546

Q5VZL5
SCVVAFQNLFNKPTG

ZMYM4

606

Q5VZL5
ECGKNFTQSSNLIVH

ZNF195

526

O14628
GLNQCFTTAQSKVFQ

ZNF254

141

O75437
CGKGFSQNSTLIIHQ

ZNF175

396

Q9Y473
QFVLTAGCAADQAKQ

UBALD1

16

Q8TB05
KATSNICTAQALLAN

GLDC

376

P23378
ASNKAFVVNNLVSGT

LRFN2

471

Q9ULH4
DCNGIFRINVSVSKN

NALCN

1056

Q8IZF0
SNCVLEAFGNAKTNR

MYO1D

141

O94832