Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	adenylate cyclase activity	GUCY2F GUCY2D ADCY2	1.65e-05	18	56	3	GO:0004016
GeneOntologyMolecularFunction	cyclase activity	GUCY2F GUCY2D ADCY2	4.06e-05	24	56	3	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	GUCY2F GUCY2D ADCY2	4.60e-05	25	56	3	GO:0016849
GeneOntologyMolecularFunction	guanylate cyclase activity	GUCY2F GUCY2D	3.43e-04	10	56	2	GO:0004383
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9C1 SLC17A6	6.88e-04	14	56	2	GO:0015386
GeneOntologyBiologicalProcess	cyclic nucleotide biosynthetic process	GUCY2F GUCY2D ADCY2	3.41e-05	23	57	3	GO:0009190
GeneOntologyBiologicalProcess	negative regulation of lysosome organization	FLCN BECN1	4.49e-05	4	57	2	GO:1905672
GeneOntologyCellularComponent	organelle outer membrane	SYNE3 GUCY2F GUCY2D COASY BECN1 PINK1	1.21e-04	279	58	6	GO:0031968
GeneOntologyCellularComponent	outer membrane	SYNE3 GUCY2F GUCY2D COASY BECN1 PINK1	1.26e-04	281	58	6	GO:0019867
GeneOntologyCellularComponent	nuclear outer membrane	SYNE3 GUCY2F GUCY2D	1.86e-04	40	58	3	GO:0005640
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8B3 ATP8B4	6.74e-04	14	58	2	GO:1990531
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	BRD4 POLR1B PFKL BECN1 TRRAP	2.35e-03	335	58	5	GO:0061695
GeneOntologyCellularComponent	photoreceptor disc membrane	GUCY2F GUCY2D	2.36e-03	26	58	2	GO:0097381
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	CHMP7 ATP8B3 MRC1 DMXL2 ATP8B4 SCNN1B TLR7 BECN1 SERPINA5 SLC17A6	2.94e-03	1307	58	10	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	CHMP7 ATP8B3 MRC1 DMXL2 ATP8B4 SCNN1B TLR7 BECN1 SERPINA5 SLC17A6	3.25e-03	1325	58	10	GO:0012506
Domain	DUF3657	FAM135A FAM135B	9.15e-06	2	57	2	IPR022122
Domain	DUF676	FAM135A FAM135B	9.15e-06	2	57	2	PF05057
Domain	DUF3657	FAM135A FAM135B	9.15e-06	2	57	2	PF12394
Domain	DUF676_lipase-like	FAM135A FAM135B	9.15e-06	2	57	2	IPR007751
Domain	A/G_cyclase_CS	GUCY2F GUCY2D ADCY2	1.78e-05	17	57	3	IPR018297
Domain	Nucleotide_cyclase	GUCY2F GUCY2D ADCY2	2.13e-05	18	57	3	IPR029787
Domain	-	GUCY2F GUCY2D ADCY2	2.13e-05	18	57	3	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	GUCY2F GUCY2D ADCY2	2.52e-05	19	57	3	PS00452
Domain	Guanylate_cyc	GUCY2F GUCY2D ADCY2	2.52e-05	19	57	3	PF00211
Domain	GUANYLATE_CYCLASE_2	GUCY2F GUCY2D ADCY2	2.52e-05	19	57	3	PS50125
Domain	A/G_cyclase	GUCY2F GUCY2D ADCY2	2.52e-05	19	57	3	IPR001054
Domain	CYCc	GUCY2F GUCY2D ADCY2	2.52e-05	19	57	3	SM00044
Domain	Sox7/17/18_central	SOX7 SOX17	2.74e-05	3	57	2	IPR033392
Domain	Sox17_18_mid	SOX7 SOX17	2.74e-05	3	57	2	PF12067
Domain	Sox_C	SOX7 SOX17	2.74e-05	3	57	2	IPR021934
Domain	SOX_C	SOX7 SOX17	2.74e-05	3	57	2	PS51516
Domain	-	ATP8B3 ATP8B4 ATP12A	1.26e-04	32	57	3	3.40.1110.10
Domain	-	ATP8B3 ATP8B4 ATP12A	1.26e-04	32	57	3	2.70.150.10
Domain	HNOB_dom_associated	GUCY2F GUCY2D	1.36e-04	6	57	2	IPR011645
Domain	HNOBA	GUCY2F GUCY2D	1.36e-04	6	57	2	PF07701
Domain	ATPase_P-typ_cyto_domN	ATP8B3 ATP8B4 ATP12A	1.65e-04	35	57	3	IPR023299
Domain	P_typ_ATPase	ATP8B3 ATP8B4 ATP12A	1.79e-04	36	57	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP8B3 ATP8B4 ATP12A	1.79e-04	36	57	3	IPR018303
Domain	ATPASE_E1_E2	ATP8B3 ATP8B4 ATP12A	1.79e-04	36	57	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8B3 ATP8B4 ATP12A	1.95e-04	37	57	3	IPR008250
Domain	E1-E2_ATPase	ATP8B3 ATP8B4 ATP12A	1.95e-04	37	57	3	PF00122
Domain	Hydrolase_3	ATP8B3 ATP8B4	4.05e-04	10	57	2	PF08282
Domain	P_typ_ATPase_c	ATP8B3 ATP8B4	8.13e-04	14	57	2	IPR032630
Domain	P-type_ATPase_N	ATP8B3 ATP8B4	8.13e-04	14	57	2	IPR032631
Domain	P-type_ATPase_IV	ATP8B3 ATP8B4	8.13e-04	14	57	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B3 ATP8B4	8.13e-04	14	57	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B3 ATP8B4	8.13e-04	14	57	2	PF16209
Domain	Integrin_alpha_C_CS	ITGA1 ITGA7	1.07e-03	16	57	2	IPR018184
Domain	Integrin_alpha-2	ITGA1 ITGA7	1.36e-03	18	57	2	IPR013649
Domain	Integrin_alpha2	ITGA1 ITGA7	1.36e-03	18	57	2	PF08441
Domain	Integrin_alpha	ITGA1 ITGA7	1.36e-03	18	57	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGA1 ITGA7	1.36e-03	18	57	2	PS00242
Domain	Int_alpha_beta-p	ITGA1 ITGA7	1.51e-03	19	57	2	IPR013519
Domain	Int_alpha	ITGA1 ITGA7	1.51e-03	19	57	2	SM00191
Domain	HAD-like_dom	ATP8B3 ATP8B4 ATP12A	1.81e-03	79	57	3	IPR023214
Domain	FG_GAP	ITGA1 ITGA7	2.03e-03	22	57	2	PS51470
Domain	FG-GAP	ITGA1 ITGA7	2.42e-03	24	57	2	PF01839
Domain	FG-GAP	ITGA1 ITGA7	2.42e-03	24	57	2	IPR013517
Domain	Integrin_dom	ITGA1 ITGA7	2.62e-03	25	57	2	IPR032695
Domain	Serpin_CS	SERPINA1 SERPINA5	4.28e-03	32	57	2	IPR023795
Domain	Serpin_dom	SERPINA1 SERPINA5	5.39e-03	36	57	2	IPR023796
Domain	ANF_lig-bd_rcpt	GUCY2F GUCY2D	5.69e-03	37	57	2	IPR001828
Domain	SERPIN	SERPINA1 SERPINA5	5.69e-03	37	57	2	SM00093
Domain	ANF_receptor	GUCY2F GUCY2D	5.69e-03	37	57	2	PF01094
Domain	SERPIN	SERPINA1 SERPINA5	5.69e-03	37	57	2	PS00284
Domain	Serpin	SERPINA1 SERPINA5	6.00e-03	38	57	2	PF00079
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 SLC9C1 ATP8B4 CLIC2 SCNN1B ATP12A	1.80e-05	183	43	6	M997
Pubmed	Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.	GUCY2F GUCY2D	2.73e-06	2	58	2	7777544
Pubmed	Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.	SOX7 SOX17	2.73e-06	2	58	2	18682240
Pubmed	The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors.	GUCY2F GUCY2D	2.73e-06	2	58	2	17255100
Pubmed	PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage.	BECN1 PINK1	2.73e-06	2	58	2	35203326
Pubmed	PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation.	BECN1 PINK1	2.73e-06	2	58	2	28368777
Pubmed	Expandable endodermal progenitors: new tools to explore endoderm and its derivatives.	SOX7 SOX17	8.19e-06	3	58	2	18940723
Pubmed	FBG1 Is the Final Arbitrator of A1AT-Z Degradation.	SERPINA1 BECN1	8.19e-06	3	58	2	26295339
Pubmed	The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms.	SOX7 SOX17	8.19e-06	3	58	2	19328208
Pubmed	Dll4 Blockade Promotes Angiogenesis in Nonhealing Wounds of Sox7-Deficient Mice.	SOX7 SOX17	8.19e-06	3	58	2	33095124
Pubmed	Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge.	BECN1 PINK1	8.19e-06	3	58	2	29844467
Pubmed	Genetic mapping of the integrin alpha 1 gene (Vla1) to mouse chromosome 13.	GZMA ITGA1	8.19e-06	3	58	2	1427867
Pubmed	Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase.	GUCY2F GUCY2D	8.19e-06	3	58	2	34537244
Pubmed	RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.	GUCY2F GUCY2D	1.64e-05	4	58	2	21078983
Pubmed	Retinal guanylyl cyclase isozyme 1 is the preferential in vivo target for constitutively active GCAP1 mutants causing congenital degeneration of photoreceptors.	GUCY2F GUCY2D	1.64e-05	4	58	2	22623665
Pubmed	The kinase homology domain of retinal guanylyl cyclases 1 and 2 specifies the affinity and cooperativity of interaction with guanylyl cyclase activating protein-2.	GUCY2F GUCY2D	1.64e-05	4	58	2	9698373
Pubmed	SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene.	SOX7 SOX17	1.64e-05	4	58	2	15220343
Pubmed	Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos.	SOX7 SOX17	1.64e-05	4	58	2	17610846
Pubmed	FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body.	ATP8B3 ATP8B4	1.64e-05	4	58	2	12880872
Pubmed	Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality.	SOX7 SOX17	1.64e-05	4	58	2	29444818
Pubmed	Role of the mannose receptor in phagocytosis of Enterococcus faecalis strain EC-12 by antigen-presenting cells.	MRC1 TLR7	1.64e-05	4	58	2	23801521
Pubmed	SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.	SOX7 SOX17	1.64e-05	4	58	2	28619820
Pubmed	Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.	GUCY2F GUCY2D	2.72e-05	5	58	2	23082185
Pubmed	Regionalization of cell fates and cell movement in the endoderm of the mouse gastrula and the impact of loss of Lhx1(Lim1) function.	SOX7 SOX17	2.72e-05	5	58	2	15355796
Pubmed	SoxF Transcription Factors Are Positive Feedback Regulators of VEGF Signaling.	SOX7 SOX17	2.72e-05	5	58	2	27528602
Pubmed	SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation.	BECN1 PINK1	2.72e-05	5	58	2	29330382
Pubmed	Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors.	GUCY2F GUCY2D	2.72e-05	5	58	2	21598940
Pubmed	Retinal guanylyl cyclase activation by calcium sensor proteins mediates photoreceptor degeneration in an rd3 mouse model of congenital human blindness.	GUCY2F GUCY2D	2.72e-05	5	58	2	31346032
Pubmed	Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein.	GUCY2F GUCY2D	2.72e-05	5	58	2	27471269
Pubmed	Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.	SERPINA1 SERPINA5	4.08e-05	6	58	2	15853774
Pubmed	Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice.	SOX7 SOX17	4.08e-05	6	58	2	19515696
Pubmed	SOX7 and GATA-4 are competitive activators of Fgf-3 transcription.	SOX7 SOX17	4.08e-05	6	58	2	15082719
Pubmed	Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.	SOX7 SOX17	4.08e-05	6	58	2	29635272
Pubmed	Chromosomal localization and genomic organization of genes encoding guanylyl cyclase receptors expressed in olfactory sensory neurons and retina.	GUCY2F GUCY2D	5.71e-05	7	58	2	8838319
Pubmed	CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.	ATP8B3 ATP8B4	5.71e-05	7	58	2	20961850
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	ITGA1 ITGA7	5.71e-05	7	58	2	9004048
Pubmed	SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development.	SOX7 SOX17	5.71e-05	7	58	2	28577909
Pubmed	AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.	BECN1 PINK1	5.71e-05	7	58	2	25215947
Pubmed	The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner.	SOX7 SOX17	7.60e-05	8	58	2	36715213
Pubmed	Developmental regulation of integrin expression at the time of implantation in the mouse embryo.	ITGA1 ITGA7	7.60e-05	8	58	2	8306881
Pubmed	Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.	BECN1 NBR1	9.77e-05	9	58	2	36221902
Pubmed	A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse.	SOX7 SOX17	9.77e-05	9	58	2	30530745
Pubmed	Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages.	BECN1 PINK1	9.77e-05	9	58	2	37319285
Pubmed	Sox7-positive endothelial progenitors establish coronary arteries and govern ventricular compaction.	SOX7 SOX17	9.77e-05	9	58	2	37551717
Pubmed	High-resolution linkage map of mouse chromosome 13 in the vicinity of the host resistance locus Lgn1.	GZMA ITGA1	1.22e-04	10	58	2	9119362
Pubmed	The expression of Sox17 identifies and regulates haemogenic endothelium.	SOX7 SOX17	1.49e-04	11	58	2	23604320
Pubmed	Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.	GZMA TLR7	1.49e-04	11	58	2	31293597
Pubmed	The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.	SOX7 SOX17	1.49e-04	11	58	2	21146513
Pubmed	Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.	ITGA1 ITGA7	1.49e-04	11	58	2	15739233
Pubmed	Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease.	BECN1 NBR1	1.49e-04	11	58	2	32093570
Pubmed	Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice.	SOX7 SOX17	1.78e-04	12	58	2	16895970
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP8B3 ATP8B4	2.11e-04	13	58	2	11015572
Pubmed	Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules.	BECN1 NBR1	2.11e-04	13	58	2	36692217
Pubmed	Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.	ITGA1 ITGA7	2.11e-04	13	58	2	20563599
Pubmed	Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.	SOX7 SOX17	2.11e-04	13	58	2	22962592
Pubmed	Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst.	SOX7 SOX17	2.11e-04	13	58	2	23747191
Pubmed	Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.	SOX7 SOX17	2.46e-04	14	58	2	8921394
Pubmed	Depletion of definitive gut endoderm in Sox17-null mutant mice.	SOX7 SOX17	2.46e-04	14	58	2	11973269
Pubmed	Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.	SOX7 SOX17	2.83e-04	15	58	2	26630461
Pubmed	Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types.	SOX7 SOX17	2.83e-04	15	58	2	28512199
Pubmed	SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.	SOX7 SOX17	2.83e-04	15	58	2	29882512
Pubmed	Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.	ITGA1 ITGA7	2.83e-04	15	58	2	15366018
Pubmed	Integrin requirement for hippocampal synaptic plasticity and spatial memory.	ITGA1 ITGA7	3.23e-04	16	58	2	12904471
Pubmed	Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.	SOX7 SOX17	3.66e-04	17	58	2	25912690
Pubmed	Spatio-temporal expression of Sox genes in murine palatogenesis.	SOX7 SOX17	3.66e-04	17	58	2	27241892
Pubmed	Expression of Sox genes in tooth development.	SOX7 SOX17	4.11e-04	18	58	2	26864488
Pubmed	An integrated genetic map of the pearl locus of mouse chromosome 13.	GZMA ITGA1	4.59e-04	19	58	2	8828042
Pubmed	HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.	SOX7 SOX17	5.09e-04	20	58	2	25340657
Pubmed	Sox17 is indispensable for acquisition and maintenance of arterial identity.	SOX7 SOX17	5.09e-04	20	58	2	24153254
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA7 SLC17A6	5.09e-04	20	58	2	22687584
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TRAF1 ADRM1 PFKL BECN1 BABAM2 NBR1	5.21e-04	608	58	6	16713569
Pubmed	Expression of Sox transcription factors in the developing mouse pancreas.	SOX7 SOX17	5.62e-04	21	58	2	12815626
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA1 SERPINA5	5.62e-04	21	58	2	15014966
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	ITGA1 CSMD3	6.18e-04	22	58	2	35245678
Pubmed	The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.	GUCY2F GUCY2D	6.76e-04	23	58	2	17954614
Pubmed	Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development.	ITGA7 TNNI1	6.76e-04	23	58	2	25190801
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGA1 ITGA7	6.76e-04	23	58	2	23152823
Pubmed	Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development.	SOX7 SOX17	8.00e-04	25	58	2	36046192
Pubmed	A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.	SOX7 SOX17	8.00e-04	25	58	2	19369396
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	AKAP11 PFKL ATP12A	8.37e-04	110	58	3	27889896
Pubmed	Specification of CNS macrophage subsets occurs postnatally in defined niches.	MRC1 SOX17	9.34e-04	27	58	2	35444273
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA1 ITGA7	9.34e-04	27	58	2	31541017
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	TANC2 SERPINA1 ADRM1 TRRAP FAM135A NBR1	1.24e-03	719	58	6	35337019
Pubmed	Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.	ITGA7 BECN1	1.40e-03	33	58	2	24569637
Pubmed	A SOX17-PDGFB signaling axis regulates aortic root development.	SOX7 SOX17	1.48e-03	34	58	2	35831318
Pubmed	Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.	DMXL2 SLC17A6	1.57e-03	35	58	2	37758766
Pubmed	Global Proximity Interactome of the Human Macroautophagy Pathway.	BECN1 NBR1	1.57e-03	35	58	2	34524948
Cytoband	14q32.1	SERPINA1 SERPINA5	8.56e-05	11	58	2	14q32.1
Cytoband	15q21.2	DMXL2 ATP8B4	6.23e-04	29	58	2	15q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	TTLL6 COASY BECN1 NBR1	3.04e-03	473	58	4	chr17q21
GeneFamily	Guanylate cyclase receptors	GUCY2F GUCY2D	1.15e-04	7	43	2	343
GeneFamily	ATPase phospholipid transporting	ATP8B3 ATP8B4	5.69e-04	15	43	2	1210
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA1 ITGA7	8.25e-04	18	43	2	1160
GeneFamily	SRY-boxes	SOX7 SOX17	9.21e-04	19	43	2	757
GeneFamily	Serpin peptidase inhibitors	SERPINA1 SERPINA5	3.49e-03	37	43	2	739
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9C1 GUCY2F ATP12A CSMD3 SLC17A6	1.19e-06	145	57	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MRC1 DMXL2 SERPINA1 CLIC2 SHE	2.75e-06	172	57	5	968d18ab8c3cdeb7936a2aa721a7f41525763863
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX7 SOX17 SHE ITGA1 SERPINA5	5.32e-06	197	57	5	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	mLN-Macrophage-Macrophage\|mLN / Region, Cell class and subclass	MRC1 DMXL2 SERPINA1 TTLL6 CLIC2	5.59e-06	199	57	5	6bbec8450afb30347b07da28401a698fc51a3c53
ToppCell	mLN-(6)_Macrophage-(60)_Macrophage\|mLN / shred on region, Cell_type, and subtype	MRC1 DMXL2 SERPINA1 TTLL6 CLIC2	5.59e-06	199	57	5	1ea28b832c6173b1b58da432aaf21e6cd291561e
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SERPINA1 SCNN1B IGSF1 ATP12A ADCY2	5.73e-06	200	57	5	df90b67490cd649de3e3a713762ffbc34a698899
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP5 SCNN1B ATP12A FAM135B	3.88e-05	148	57	4	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 TRAF1 ATP8B4 ITGA1	4.76e-05	156	57	4	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B3 SOX7 GUCY2D FAM135A	5.00e-05	158	57	4	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B3 SOX7 GUCY2D FAM135A	5.00e-05	158	57	4	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ATP8B3 TTLL6 TLR7	5.10e-05	56	57	3	ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ATP8B3 TTLL6 TLR7	5.10e-05	56	57	3	20a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCell	343B-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CHMP7 GUCY2D ENPP5 FAM135B	5.38e-05	161	57	4	537a1d86de99a493b0345ca0f760994260e97049
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue\|TCGA-Kidney / Sample_Type by Project: Shred V9	SCNN1B ATP12A TNNI1 SERPINA5	5.51e-05	162	57	4	a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney\|TCGA-Kidney / Sample_Type by Project: Shred V9	SCNN1B ATP12A TNNI1 SERPINA5	5.51e-05	162	57	4	d007ec42d6458431f6c490df61de7a9caef857f0
ToppCell	TCGA-Kidney-Solid_Tissue_Normal\|TCGA-Kidney / Sample_Type by Project: Shred V9	SCNN1B ATP12A TNNI1 SERPINA5	5.51e-05	162	57	4	65549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX7 SOX17 SHE ITGA1	5.78e-05	164	57	4	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX7 SOX17 SHE ITGA1	5.78e-05	164	57	4	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 GUCY2D GZMA ITGA1	6.06e-05	166	57	4	62523e635784512b3261b672beaa7747cb9d114a
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX7 SOX17 SHE ITGA1	6.06e-05	166	57	4	27af6c906cff1d40d134f0386db7708869691121
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	MRC1 SHE ITGA1 STEAP1B	6.20e-05	167	57	4	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	ATP8B4 CLIC2 SHE TLR7	6.20e-05	167	57	4	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	Control-Epithelial_airway-Club_cells-Airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SERPINA1 SCNN1B IGSF1 ADCY2	6.35e-05	168	57	4	ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCell	Control-Epithelial_airway-Club_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SERPINA1 SCNN1B IGSF1 ADCY2	6.35e-05	168	57	4	e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 GUCY2D GZMA ITGA1	6.35e-05	168	57	4	b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 GZMA ENPP5 ITGA1	6.50e-05	169	57	4	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	droplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 MRC1 TTLL6 TRRAP	6.80e-05	171	57	4	7ca404539344e14dcd90c746c9122f713a7db78b
ToppCell	droplet-Lung-nan-18m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 MRC1 TTLL6 TRRAP	6.80e-05	171	57	4	ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ATP8B3 MRC1 SYNE3 STEAP1B	6.96e-05	172	57	4	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX7 SOX17 SHE ITGA1	7.27e-05	174	57	4	b1bcd5f4505d2ccef4183fcfbf1de81964b3f9e0
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 GUCY2D GZMA ITGA1	7.60e-05	176	57	4	dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX7 SOX17 SHE TNNI1	7.60e-05	176	57	4	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX7 SOX17 SHE TNNI1	7.60e-05	176	57	4	96779273b94345250cf53ba671203345b43d9e00
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MRC1 CLIC2 SCNN1B SHE	8.12e-05	179	57	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MRC1 CLIC2 SCNN1B SHE	8.12e-05	179	57	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	TANC2 MRC1 SCNN1B ITGA1	8.12e-05	179	57	4	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX7 GZMA SOX17 SHE	8.29e-05	180	57	4	af7c4b9f1a0ddd894085cf93c29a6d253a7d077c
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX7 GZMA SOX17 SHE	8.29e-05	180	57	4	e35e9159f5cd9ec905b3b6e27d938158aeb9c51c
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	MMAA DMXL2 TMEM19	8.34e-05	66	57	3	57fd31a25addc48793d7975eadccf4c5a41a8b03
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 GUCY2D GZMA ITGA1	8.47e-05	181	57	4	ee1c5af8ed75dd8a0ed3152ba5b9a42d2a8c2ae4
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX7 GZMA SOX17 SHE	8.47e-05	181	57	4	7d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	8.47e-05	181	57	4	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	8.84e-05	183	57	4	c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	8.84e-05	183	57	4	c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	8.84e-05	183	57	4	92eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX7 CLIC2 SOX17 SHE	9.03e-05	184	57	4	df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX7 CLIC2 SOX17 SHE	9.03e-05	184	57	4	1ace70f12b417185bdd46042833f72b3b6815966
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	MRC1 DMXL2 ATP8B4 STEAP1B	9.22e-05	185	57	4	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	SOX7 SOX17 SHE ITGA1	9.22e-05	185	57	4	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MRC1 SERPINA1 ATP8B4 TLR7	9.41e-05	186	57	4	e41f14aee8cfbf76b8d0d4695a6170e2cd92aec8
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	9.41e-05	186	57	4	0cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	9.41e-05	186	57	4	86b218a400f9c64f92b050f00b49f09647b17437
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	9.41e-05	186	57	4	f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MRC1 SERPINA1 ATP8B4 TLR7	9.41e-05	186	57	4	b3633cd4e360c5b45060c50b4f606d483e03a89a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MRC1 SERPINA1 ATP8B4 TLR7	9.41e-05	186	57	4	9dd31dc9af1704f35c74de726a6c27fa21e9a014
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GUCY2D GZMA SCNN1B	9.52e-05	69	57	3	11e6747ed4a45acee210c48ba670bfe0375fb19b
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GUCY2D GZMA SCNN1B	9.52e-05	69	57	3	96564b46008a6e5220b6596cbbe0a24e9b5955ee
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	9.61e-05	187	57	4	52ffd4be374e329ac8d321063f061b826d252956
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX7 SOX17 SHE TNNI1	9.81e-05	188	57	4	59f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	ITGA1 ITGA7 TNNI1 STEAP1B	9.81e-05	188	57	4	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	9.81e-05	188	57	4	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	9.81e-05	188	57	4	05de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX7 CLIC2 SOX17 SHE	9.81e-05	188	57	4	986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX7 SOX17 SHE TNNI1	1.00e-04	189	57	4	feedac2751ed770f80bc56fec31662b5b3826f58
ToppCell	facs-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCell	facs-Heart-LV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	d424d2554595b2304219f7324406b401711af7c2
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	1.00e-04	189	57	4	4bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	8ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCell	droplet-Lung-LUNG-30m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	25db316f66cee53774bb2b286cc457b37353356c
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	facs-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCell	facs-Trachea-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCell	facs-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	5559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.00e-04	189	57	4	bec57459ad4bab15b2532b57722549fec2e771fb
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	b7fc451e160e31dc898b122de844b501f587db67
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	06bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell	21-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	MRC1 SOX7 SOX17 SHE	1.02e-04	190	57	4	bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MRC1 SYNE3 FLCN SLC49A3	1.02e-04	190	57	4	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	5174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	83cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	5f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCell	21-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	MRC1 SOX7 SOX17 SHE	1.02e-04	190	57	4	08437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.02e-04	190	57	4	90e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	1.06e-04	192	57	4	f68e6cbde87678122da1b5c0061904cfb7d04bf5
ToppCell	EC\|World / Lineage and Cell class	MRC1 SOX7 SOX17 SHE	1.06e-04	192	57	4	478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.06e-04	192	57	4	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	droplet-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.06e-04	192	57	4	42e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX7 SOX17 SHE ITGA1	1.06e-04	192	57	4	6b69bb8fab9b470850eba1a070a500435ec233cd
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX7 SOX17 SHE ITGA1	1.06e-04	192	57	4	4fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX17 SHE ITGA1 SERPINA5	1.09e-04	193	57	4	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MRC1 SOX7 SOX17 SHE	1.09e-04	193	57	4	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX7 SOX17 SHE ITGA1	1.09e-04	193	57	4	ce5c3ab79900aa6f394c894267340167009c6149
Disease	neutrophil elastase measurement	SERPINA1 ATP8B4	2.27e-05	4	58	2	EFO_0020605
Disease	kallistatin measurement	SERPINA1 SERPINA5	1.06e-04	8	58	2	EFO_0008196
Disease	alpha-1-antitrypsin measurement	SERPINA1 SERPINA5	1.35e-04	9	58	2	EFO_0008327
Disease	Lung diseases	SERPINA1 SCNN1B FLCN	4.94e-04	78	58	3	C0024115
Disease	serum non-albumin protein measurement	CHMP7 TRAF1 TTLL6 GUCY2D STEAP1B	7.18e-04	361	58	5	EFO_0004568
Disease	Bronchiectasis	SERPINA1 SCNN1B	8.55e-04	22	58	2	C0006267
Disease	response to paliperidone, schizophrenia symptom severity measurement	SERPINA1 C3orf38 CSMD3 SLC17A6	8.70e-04	216	58	4	EFO_0007925, EFO_0007927
Disease	serum albumin measurement	MRC1 SERPINA1 ITGA1 STEAP1B BABAM2 SERPINA5	1.06e-03	592	58	6	EFO_0004535
Disease	Glioblastoma Multiforme	GUCY2F BRD4 PINK1	1.38e-03	111	58	3	C1621958

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKMGIKSGFTFWNLV	CSMD3	36	Q7Z407
KKDLKIKNMGSWASL	BRD4	1191	O60885
CKKLSSWVLLMKYLG	SERPINA1	256	P01009
LSKKHLNWIIMTIKG	GZMA	246	P12544
KEFMLLSKQLQEKGW	AKAP11	1851	Q9UKA4
ILMGKSFKQKKWQDL	ATP8B3	221	O60423
NKLDKFMGILSWKDS	ATP8B4	206	Q8TF62
LSMKKKAVVWGLFRS	DMXL2	1671	Q8TDJ6
NVKLLKFWMTGLSKT	FLCN	546	Q8NFG4
IKLDWMFKSSLLLDL	GUCY2D	636	Q02846
KFLKQMVGGFSILLW	ATP12A	106	P54707
TKALKFMLTNLKWGL	BECN1	426	Q14457
FMQKWKKSGSLLQLT	FAM135A	1376	Q9P2D6
ILALKNLKLDKMVGW	PINK1	516	Q9BXM7
TKLGVKAMLWLSEKL	PFKL	676	P17858
GYLIQMLKKAKLWNT	ENPP5	216	Q9UJA9
CTKWMLLSDGLKRKL	MMAA	51	Q8IVH4
LMLLILALWKIGFFK	ITGA1	1156	P56199
SSLSSKKMWGVLQKK	IKZF5	171	Q9H5V7
NWKKIVLGTMLLASK	CCNYL3	116	P0C7X3
KKASPLLMWLLKSSG	ADCY2	656	Q08462
SKFLLLKDKTQMTWI	IGSF1	66	Q8N6C5
KKGWLKTMLNFFVRT	BNIP5	96	P0C671
AEGFTKLTLLLMWKD	BABAM2	291	Q9NXR7
LMKRFGLKATTKINW	EFCAB6	341	Q5THR3
FLLKPLKWTLSNMLG	CHMP7	126	Q8WUX9
WKIKFINLKIMGESS	C3orf38	266	Q5JPI3
KLDWMFKSSLLLDLI	GUCY2F	641	P51841
GLSEKTLRKWLKMFK	SERPINA5	281	P05154
LALLVLLLWKMGFFK	ITGA7	1096	Q13683
WLMQKLKKSGSLLQL	FAM135B	1266	Q49AJ0
PKKKAMWFLLTLLFA	SCNN1B	46	P51168
LKSMGAPFIFIKNWK	RXYLT1	376	Q9Y2B1
LFMILWLKGVKFNVT	CLIC2	36	O15247
FIGLLISLDKKFAWM	MRC1	861	P22897
AELSKMLGKSWKALT	SOX17	96	Q9H6I2
MLGKSWKALTLAEKR	SOX17	101	Q9H6I2
SKMLGKSWKALTLSQ	SOX7	76	Q9BT81
LKKMASLARKASLWL	TRIM48	86	Q8IWZ4
KMWLKLGLAITARKI	SLC9C1	996	Q4G0N8
QWMLYKSKLKDSGHL	SYNE3	881	Q6ZMZ3
KLKFMWGNLTLASTE	NBR1	411	Q14596
KSLMHTLWAKFKLNR	NANOGNB	111	Q7Z5D8
FLSKMIGKFPSWLKL	TANC2	561	Q9HCD6
DKWMLTRKQFGLLSL	STEAP1B	136	Q6NZ63
LKFKAGSKRLFFWMQ	ADRM1	96	Q16186
FGNKKQLKILTDIMW	COASY	431	Q13057
TSEKFLDGLKLQLMW	SLC49A3	231	Q6UXD7
NLLGAMEKFKTPWRK	SLC17A6	291	Q9P2U8
LLLKSLMLAKAKECW	TNNI1	16	P19237
LNLLLGFMKQWKARL	TRAF1	116	Q13077
KMLKSFLPTKSKSFW	TTLL6	691	Q8N841
SLAKNGLKSFSWKKL	TLR7	681	Q9NYK1
LMFFLSSSKLTKWKG	TMEM19	101	Q96HH6
LAITFKKLIAMWKEG	ZCCHC4	286	Q9H5U6
FLMFLKEKLEGWLVS	POLR1B	381	Q9H9Y6
LMAAKWFKEFPLNLK	SHE	36	Q5VZ18
KSELKLQWFDKLLMT	TRRAP	2141	Q9Y4A5
AWSVSLKIFGKMNLK	NLRP14	71	Q86W24