Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	PRRG4 FBLN5 FBN1 ADGRE1 SYT3 LTBP4 LDLR FBN3 PROS1 GAS6	9.46e-07	749	38	10	GO:0005509
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBLN5 FBN1	2.30e-04	12	38	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBLN5 FBN1	3.16e-04	14	38	2	GO:0097493
GeneOntologyMolecularFunction	integrin binding	FBLN5 FBN1 LTBP4 ADAM22	3.33e-04	175	38	4	GO:0005178
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBLN5 FBN1 LTBP4 FBN3	4.37e-04	188	38	4	GO:0005201
GeneOntologyCellularComponent	microfibril	FBN1 LTBP4 FBN3	1.33e-06	13	36	3	GO:0001527
GeneOntologyCellularComponent	supramolecular fiber	FBLN5 FBN1 DIAPH3 ACTL8 LTBP4 TCAP FBN3 SLMAP	7.34e-04	1179	36	8	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	FBLN5 FBN1 DIAPH3 ACTL8 LTBP4 TCAP FBN3 SLMAP	7.67e-04	1187	36	8	GO:0099081
HumanPheno	Abnormal aortic morphology	FANCD2 SAMHD1 FBLN5 FBN1 PTEN LDLR UBE3B SOS2	1.01e-05	401	16	8	HP:0001679
HumanPheno	Emphysema	FBLN5 FBN1 PTEN LTBP4	3.68e-05	64	16	4	HP:0002097
HumanPheno	Abnormal aortic morphology	SAMHD1 FBLN5 FBN1 PTEN LDLR UBE3B SOS2	5.74e-05	363	16	7	HP:0030963
HumanPheno	Multiple bladder diverticula	FBLN5 LTBP4	9.20e-05	5	16	2	HP:0012619
HumanPheno	Abnormal morphology of the great vessels	FANCD2 SAMHD1 FBLN5 FBN1 PTEN LTBP4 LDLR UBE3B SOS2	1.15e-04	736	16	9	HP:0030962
HumanPheno	Genu recurvatum	FBLN5 FBN1 PTEN	1.43e-04	34	16	3	HP:0002816
HumanPheno	Abnormal blood vessel morphology	FANCD2 SAMHD1 FBLN5 FBN1 PTEN LTBP4 TCAP LDLR UBE3B PROS1 SOS2	1.58e-04	1201	16	11	HP:0033353
MousePheno	abnormal aorta elastic fiber morphology	FBLN5 FBN1 LTBP4	2.58e-06	14	28	3	MP:0003211
MousePheno	abnormal aorta elastic tissue morphology	FBLN5 FBN1 LTBP4	1.08e-05	22	28	3	MP:0009862
MousePheno	abnormal blood vessel elastic tissue morphology	FBLN5 FBN1 LTBP4	1.42e-05	24	28	3	MP:0006083
MousePheno	emphysema	FBLN5 FBN1 LTBP4	5.34e-05	37	28	3	MP:0001958
MousePheno	abnormal thrombosis	FBLN5 FBN1 PROS1 GAS6	5.56e-05	106	28	4	MP:0005048
MousePheno	abnormal aorta tunica media morphology	FBLN5 FBN1 LTBP4	6.27e-05	39	28	3	MP:0009873
MousePheno	abnormal aorta wall morphology	FBLN5 FBN1 LTBP4	1.32e-04	50	28	3	MP:0009866
MousePheno	increased aorta wall thickness	FBN1 LTBP4	1.38e-04	9	28	2	MP:0010996
MousePheno	abnormal susceptibility to induced thrombosis	FBLN5 PROS1 GAS6	1.58e-04	53	28	3	MP:0020408
MousePheno	decreased erythroblast number	FANCD2 DIAPH3	2.52e-04	12	28	2	MP:0011179
MousePheno	abnormal blood vessel morphology	FANCD2 TRIM45 FBLN5 FBN1 PTEN LTBP4 LDLR UBE3B MOV10 PROS1	3.59e-04	1472	28	10	MP:0001614
Domain	EGF_CA	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	7.93e-12	86	39	8	PF07645
Domain	EGF_Ca-bd_CS	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	2.13e-11	97	39	8	IPR018097
Domain	EGF_CA	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	2.51e-11	99	39	8	PS01187
Domain	ASX_HYDROXYL	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	2.73e-11	100	39	8	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	4.38e-11	106	39	8	IPR000152
Domain	EGF_CA	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	1.36e-10	122	39	8	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	1.56e-10	124	39	8	IPR001881
Domain	GOLGA6L	GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4	2.43e-10	6	39	4	IPR026737
Domain	Growth_fac_rcpt_	FBLN5 FBN1 ADGRE1 LTBP4 LDLR FBN3 PROS1 GAS6	9.77e-10	156	39	8	IPR009030
Domain	EGF_3	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	1.03e-09	235	39	9	PS50026
Domain	EGF	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	1.03e-09	235	39	9	SM00181
Domain	EGF-like_dom	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	1.72e-09	249	39	9	IPR000742
Domain	cEGF	FBLN5 FBN1 ADGRE1 FBN3 GAS6	1.94e-09	26	39	5	IPR026823
Domain	cEGF	FBLN5 FBN1 ADGRE1 FBN3 GAS6	1.94e-09	26	39	5	PF12662
Domain	EGF_1	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	2.12e-09	255	39	9	PS00022
Domain	EGF-like_CS	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	2.60e-09	261	39	9	IPR013032
Domain	EGF_2	FBLN5 FBN1 ADGRE1 LTBP4 LDLR ADAM22 FBN3 PROS1 GAS6	2.97e-09	265	39	9	PS01186
Domain	GOLGA2L5	GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4	4.86e-08	18	39	4	PF15070
Domain	Golgin_A	GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4	4.86e-08	18	39	4	IPR024858
Domain	TB	FBN1 LTBP4 FBN3	2.93e-07	7	39	3	PF00683
Domain	-	FBN1 LTBP4 FBN3	4.68e-07	8	39	3	3.90.290.10
Domain	TB	FBN1 LTBP4 FBN3	7.01e-07	9	39	3	PS51364
Domain	TB_dom	FBN1 LTBP4 FBN3	7.01e-07	9	39	3	IPR017878
Domain	Coagulation_fac_subgr_Gla_dom	PRRG4 PROS1 GAS6	1.83e-06	12	39	3	IPR017857
Domain	-	PRRG4 PROS1 GAS6	1.83e-06	12	39	3	4.10.740.10
Domain	GLA	PRRG4 PROS1 GAS6	3.02e-06	14	39	3	SM00069
Domain	Gla	PRRG4 PROS1 GAS6	3.02e-06	14	39	3	PF00594
Domain	GLA_1	PRRG4 PROS1 GAS6	3.02e-06	14	39	3	PS00011
Domain	GLA_domain	PRRG4 PROS1 GAS6	3.02e-06	14	39	3	IPR000294
Domain	GLA_2	PRRG4 PROS1 GAS6	3.02e-06	14	39	3	PS50998
Domain	CCDC85	CCDC85C CCDC85B	1.27e-05	3	39	2	IPR019359
Domain	CCDC85	CCDC85C CCDC85B	1.27e-05	3	39	2	PF10226
Domain	FBN	FBN1 FBN3	1.27e-05	3	39	2	IPR011398
Domain	Laminin_G_1	PROS1 GAS6	2.31e-04	11	39	2	PF00054
Domain	-	PDZRN3 PDZRN4	3.81e-04	14	39	2	3.90.890.10
Domain	SIAH-type	PDZRN3 PDZRN4	5.01e-04	16	39	2	IPR013323
Domain	TRAF-like	PDZRN3 PDZRN4	1.14e-03	24	39	2	IPR008974
Domain	hEGF	FBN3 GAS6	1.55e-03	28	39	2	PF12661
Domain	EGF	FBN3 PROS1 GAS6	2.29e-03	126	39	3	PF00008
Domain	LAM_G_DOMAIN	PROS1 GAS6	2.85e-03	38	39	2	PS50025
Domain	Laminin_G_2	PROS1 GAS6	3.15e-03	40	39	2	PF02210
Domain	LamG	PROS1 GAS6	3.80e-03	44	39	2	SM00282
Domain	Znf_RING_CS	TRIM45 PDZRN3 PDZRN4	4.74e-03	163	39	3	IPR017907
Domain	Laminin_G	PROS1 GAS6	6.52e-03	58	39	2	IPR001791
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN5 FBN1 LTBP4 FBN3	5.76e-07	37	26	4	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN5 FBN1 LTBP4 FBN3	1.17e-06	44	26	4	M26969
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN5 FBN1 LTBP4	2.67e-05	32	26	3	MM14854
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN5 FBN1 LTBP4	4.87e-05	39	26	3	MM14601
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP4	9.10e-05	8	26	2	M47850
Pathway	REACTOME_TRANSPORT_OF_GAMMA_CARBOXYLATED_PROTEIN_PRECURSORS_FROM_THE_ENDOPLASMIC_RETICULUM_TO_THE_GOLGI_APPARATUS	PROS1 GAS6	1.17e-04	9	26	2	MM14614
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	PTEN MOV10	1.17e-04	9	26	2	M27810
Pathway	REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS	PROS1 GAS6	1.46e-04	10	26	2	M26977
Pathway	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	PROS1 GAS6	1.78e-04	11	26	2	M12484
Pathway	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	PROS1 GAS6	1.78e-04	11	26	2	MM14615
Pathway	WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE	PTEN GAS6 SOS2	4.81e-04	84	26	3	M39839
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 FBN3	9.56e-04	25	26	2	M39713
Pathway	WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT	PTEN LDLR SOS2	1.05e-03	110	26	3	M39492
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBLN5 FBN1 LTBP4	3.03e-08	6	41	3	19349279
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	HNF1B FBN1 DIAPH3 CNTROB LDLR MCM3AP	7.79e-08	184	41	6	32908313
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	FBLN5 FBN1 LTBP4 LDLR PROS1 GAS6	4.51e-07	248	41	6	24006456
Pubmed	Replication Study of the Association of GAS6 and PROS1 Polymorphisms with Behçet's Disease in a Japanese Population.	PROS1 GAS6	1.36e-06	2	41	2	37133403
Pubmed	Duodenal mucosa of untreated celiac disease patients has altered expression of the GAS6 and PROS1 and the negative regulator tyrosine kinase TAM receptors subfamily.	PROS1 GAS6	1.36e-06	2	41	2	38575045
Pubmed	DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries.	FBLN5 LDLR	1.36e-06	2	41	2	10428823
Pubmed	Plasma concentrations of growth arrest-specific protein 6 and protein S in patients with acute pancreatitis.	PROS1 GAS6	1.36e-06	2	41	2	19744001
Pubmed	Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5.	FBLN5 LTBP4	1.36e-06	2	41	2	23382201
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	1.36e-06	2	41	2	15221638
Pubmed	Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity.	PROS1 GAS6	1.36e-06	2	41	2	23497733
Pubmed	Opposite Roles of MerTK Ligands Gas6 and Protein S During Retinal Phagocytosis.	PROS1 GAS6	1.36e-06	2	41	2	29721990
Pubmed	Modulation of protein S and growth arrest specific 6 protein signaling inhibits pancreatic cancer cell survival and proliferation.	PROS1 GAS6	1.36e-06	2	41	2	32945517
Pubmed	Protein S and Gas6 induce efferocytosis of HIV-1-infected cells.	PROS1 GAS6	1.36e-06	2	41	2	29304470
Pubmed	DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner.	FBLN5 FBN1	4.06e-06	3	41	2	19167375
Pubmed	Fibulin-5 interacts with fibrillin-1 molecules and microfibrils.	FBLN5 FBN1	4.06e-06	3	41	2	15790312
Pubmed	Identification and characterization of PDZRN3 and PDZRN4 genes in silico.	PDZRN3 PDZRN4	4.06e-06	3	41	2	15010864
Pubmed	Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa.	FBLN5 LTBP4	4.06e-06	3	41	2	22829427
Pubmed	Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.	FBLN5 LTBP4	4.06e-06	3	41	2	25713297
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 LTBP4	8.12e-06	4	41	2	12429738
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN3	8.12e-06	4	41	2	25034023
Pubmed	Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.	FBLN5 FBN1	8.12e-06	4	41	2	15610515
Pubmed	Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.	PROS1 GAS6	1.35e-05	5	41	2	23259948
Pubmed	Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.	PROS1 GAS6	1.35e-05	5	41	2	25265470
Pubmed	Cell-intrinsic regulation of murine epidermal Langerhans cells by protein S.	PROS1 GAS6	1.35e-05	5	41	2	29871951
Pubmed	Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.	PROS1 GAS6	1.35e-05	5	41	2	22043818
Pubmed	Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.	FBLN5 FBN1	1.35e-05	5	41	2	17255108
Pubmed	Differential regulation of elastic fiber formation by fibulin-4 and -5.	FBLN5 FBN1	1.35e-05	5	41	2	19570982
Pubmed	TAM receptors regulate multiple features of microglial physiology.	PROS1 GAS6	1.35e-05	5	41	2	27049947
Pubmed	Function of latent TGFβ binding protein 4 and fibulin 5 in elastogenesis and lung development.	FBLN5 LTBP4	1.35e-05	5	41	2	24962333
Pubmed	DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.	CCDC85C CCDC85B	2.84e-05	7	41	2	25009281
Pubmed	Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.	PROS1 GAS6	3.78e-05	8	41	2	19729839
Pubmed	Analysis of the DNA sequence and duplication history of human chromosome 15.	GOLGA6L10 GOLGA6L19 GOLGA6L4	4.04e-05	56	41	3	16572171
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FANCD2 TTC39A ACTL8 LTBP4 LDLR PDZRN3 MCM3AP GAS6	4.08e-05	1116	41	8	31753913
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	FBN1 PTEN LDLR	4.26e-05	57	41	3	23788249
Pubmed	Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis.	PROS1 GAS6	1.22e-04	14	41	2	30735494
Pubmed	E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3.	LTBP4 MCM3AP	1.41e-04	15	41	2	18276110
Pubmed	α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.	FBLN5 FBN1	1.41e-04	15	41	2	25670798
Pubmed	Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity.	FBN1 ADGRE1	1.41e-04	15	41	2	36207400
Pubmed	Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney.	HNF1B PTEN	1.82e-04	17	41	2	24003036
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	FBN1 ADGRE1	2.05e-04	18	41	2	39040056
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	FBLN5 FBN1 LTBP4	2.34e-04	101	41	3	20551380
Pubmed	Analysis of microsatellite polymorphism in inbred knockout mice.	PTEN LDLR	2.54e-04	20	41	2	22509320
Pubmed	Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.	FBLN5 FBN1	3.09e-04	22	41	2	21979435
Pubmed	Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.	CNTROB MOV10	4.67e-04	27	41	2	35709258
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FBLN5 FBN1 PTEN LTBP4 CNTROB	4.94e-04	560	41	5	21653829
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	FBLN5 FBN1 LTBP4	5.47e-04	135	41	3	28675934
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	FBLN5 FBN1	5.78e-04	30	41	2	32882513
Pubmed	Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.	HNF1B PTEN	6.17e-04	31	41	2	36656901
Pubmed	Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.	HNF1B ADGRE1	6.58e-04	32	41	2	25715394
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	FBLN5 FBN1 LTBP4	6.87e-04	146	41	3	27068509
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	FBLN5 LTBP4 CNTROB TCAP CCDC85B	7.16e-04	608	41	5	16713569
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	PDZRN3 PDZRN4	7.43e-04	34	41	2	30726710
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	FBLN5 FBN1 LTBP4	7.87e-04	153	41	3	25037231
Pubmed	Identification of transcripts with enriched expression in the developing and adult pancreas.	PPP4R1 TTC39A LTBP4 MOV10 GAS6	8.04e-04	624	41	5	18554416
Pubmed	Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.	LDLR SOS2	8.33e-04	36	41	2	9344654
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	PDZRN3 PDZRN4	8.33e-04	36	41	2	26053890
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	PPP4R1 DIAPH3 SLMAP	9.12e-04	161	41	3	32572027
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FBLN5 FBN1 LTBP4	1.01e-03	167	41	3	22159717
Pubmed	Hepatitis C virus infection protein network.	FBLN5 LTBP4	1.13e-03	42	41	2	18985028
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	FBLN5 FBN1 LTBP4	1.16e-03	175	41	3	28071719
Interaction	NTN5 interactions	FBLN5 FBN1 LTBP4 LDLR	1.24e-07	24	39	4	int:NTN5
Interaction	BRD1 interactions	FANCD2 TTC39A CNTROB LDLR PDZRN3 MCM3AP GAS6	3.82e-06	344	39	7	int:BRD1
Interaction	ZFP41 interactions	FBLN5 FBN1 LTBP4 LDLR	4.39e-06	57	39	4	int:ZFP41
Interaction	HRG interactions	FANCD2 FBLN5 FBN1 LTBP4	6.57e-06	63	39	4	int:HRG
Interaction	ADGRE1 interactions	FANCD2 ADGRE1	1.09e-05	3	39	2	int:ADGRE1
Interaction	CNTROB interactions	FANCD2 CCDC85C PTEN CNTROB SLMAP	1.64e-05	166	39	5	int:CNTROB
Interaction	ST8SIA6 interactions	FANCD2 PTEN	2.18e-05	4	39	2	int:ST8SIA6
Interaction	ZNF764 interactions	FBLN5 GOLGA6L9 LTBP4 CCDC85B	3.09e-05	93	39	4	int:ZNF764
Interaction	SAYSD1 interactions	FANCD2 CCDC85C CCDC85B	4.58e-05	36	39	3	int:SAYSD1
Interaction	ZNF326 interactions	FANCD2 PTEN CNTROB MOV10 SOS2	6.86e-05	224	39	5	int:ZNF326
Interaction	CRKL interactions	FANCD2 PTEN LTBP4 MOV10 SOS2	7.31e-05	227	39	5	int:CRKL
Interaction	SMTN interactions	FANCD2 PTEN MOV10	8.40e-05	44	39	3	int:SMTN
Interaction	USP2 interactions	FANCD2 GOLGA6L9 LDLR MOV10 CCDC85B	9.32e-05	239	39	5	int:USP2
Interaction	FOXD4L6 interactions	LTBP4 LDLR MCM3AP	1.16e-04	49	39	3	int:FOXD4L6
Interaction	TAB1 interactions	FANCD2 TRIM45 CNTROB MOV10 SLMAP	1.20e-04	252	39	5	int:TAB1
Interaction	ZNF415 interactions	ZNF415 LDLR	1.30e-04	9	39	2	int:ZNF415
Interaction	MFAP5 interactions	FBN1 LTBP4 LDLR	1.39e-04	52	39	3	int:MFAP5
Interaction	ZNF669 interactions	FBLN5 GOLGA6L9 LTBP4	1.39e-04	52	39	3	int:ZNF669
Interaction	OTUD5 interactions	PTEN LDLR MOV10	1.64e-04	55	39	3	int:OTUD5
Interaction	ZNF408 interactions	FBLN5 FBN1 LTBP4 LDLR	1.74e-04	145	39	4	int:ZNF408
Interaction	TRIM37 interactions	HNF1B FBN1 DIAPH3 PTEN CNTROB LDLR MCM3AP	1.82e-04	630	39	7	int:TRIM37
Interaction	PRG2 interactions	FANCD2 LTBP4 LDLR PROS1 GAS6	2.12e-04	285	39	5	int:PRG2
Cytoband	15q25.2	GOLGA6L10 GOLGA6L9 GOLGA6L4	7.38e-06	43	40	3	15q25.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q25	GOLGA6L10 GOLGA6L9 GOLGA6L4	3.73e-04	160	40	3	chr15q25
Cytoband	Ensembl 112 genes in cytogenetic band chr14q32	CCDC85C FBLN5 TTC7B SETD3	1.47e-03	566	40	4	chr14q32
Cytoband	17q12	HNF1B TCAP	3.40e-03	99	40	2	17q12
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	HNF1B TCAP	7.53e-03	149	40	2	chr17q12
GeneFamily	Gla domain containing	PROS1 GAS6	1.66e-04	13	27	2	1250
GeneFamily	Ring finger proteins	TRIM45 PDZRN3 PDZRN4	7.77e-03	275	27	3	58
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC39A TTC7B	1.27e-02	115	27	2	769
GeneFamily	PDZ domain containing	PDZRN3 PDZRN4	2.15e-02	152	27	2	1220
Coexpression	NABA_ECM_GLYCOPROTEINS	FBLN5 FBN1 LTBP4 FBN3 GAS6	1.04e-05	196	39	5	M3008
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 FBN1 LTBP4 PDZRN3 PROS1 GAS6	2.43e-08	195	41	6	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	FBLN5 FBN1 LTBP4 PDZRN3 PDZRN4	7.20e-07	184	41	5	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SAMHD1 FBLN5 FBN1 GAS6 PDZRN4	7.60e-07	186	41	5	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SAMHD1 FBLN5 FBN1 GAS6 PDZRN4	7.60e-07	186	41	5	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4 PDZRN4	8.89e-07	192	41	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4 PDZRN4	8.89e-07	192	41	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN LTBP4	9.12e-07	193	41	5	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 PROS1 GAS6	9.12e-07	193	41	5	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 LTBP4 PDZRN4	9.12e-07	193	41	5	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 PROS1 GAS6	9.12e-07	193	41	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN LTBP4	9.12e-07	193	41	5	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 PROS1 GAS6	9.12e-07	193	41	5	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN LTBP4	9.59e-07	195	41	5	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN LTBP4	9.59e-07	195	41	5	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LTBP4 PDZRN3 PROS1 GAS6	9.84e-07	196	41	5	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LTBP4 PDZRN3 PROS1 GAS6	9.84e-07	196	41	5	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN LTBP4	1.01e-06	197	41	5	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN PDZRN4	1.03e-06	198	41	5	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 LTBP4 PDZRN3 PROS1 PDZRN4	1.06e-06	199	41	5	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SAMHD1 FBLN5 FBN1 LTBP4 PROS1	1.06e-06	199	41	5	56d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN5 FBN1 LTBP4 PROS1 PDZRN4	1.09e-06	200	41	5	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN5 FBN1 LTBP4 PROS1 PDZRN4	1.09e-06	200	41	5	a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN5 FBN1 LTBP4 PROS1 PDZRN4	1.09e-06	200	41	5	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	SAMHD1 FBLN5 FBN1 LTBP4	1.75e-05	169	41	4	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SAMHD1 FBN1 LTBP4 PDZRN3	1.75e-05	169	41	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCD2 FBN1 DIAPH3 LTBP4	1.75e-05	169	41	4	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 PTEN ACTL8 LTBP4	1.75e-05	169	41	4	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAMHD1 TTC7B ADGRE1 SOS2	2.05e-05	176	41	4	76fdf211bce101e83a27d822cb399487bd107027
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN	2.09e-05	177	41	4	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SAMHD1 FBLN5 FBN1 PDZRN4	2.28e-05	181	41	4	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	Mesenchymal_cells-Adipo-CAR\|Mesenchymal_cells / Lineage and Cell class	SAMHD1 FBLN5 GAS6 PDZRN4	2.28e-05	181	41	4	1cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN5 LTBP4 PDZRN3 GAS6	2.38e-05	183	41	4	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 DIAPH3 LTBP4 PDZRN3	2.44e-05	184	41	4	4a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	SAMHD1 FBLN5 FBN1 PDZRN3	2.59e-05	187	41	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 LDLR	2.65e-05	188	41	4	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LTBP4 PDZRN3 GAS6	2.65e-05	188	41	4	b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CCDC85C HNF1B LDLR SLMAP	2.65e-05	188	41	4	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FBLN5 FBN1 LTBP4 PDZRN4	2.65e-05	188	41	4	0e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.71e-05	189	41	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.71e-05	189	41	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.71e-05	189	41	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.71e-05	189	41	4	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PDZRN3 ADAM22	2.71e-05	189	41	4	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PDZRN3 ADAM22	2.76e-05	190	41	4	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PDZRN3 ADAM22	2.76e-05	190	41	4	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.82e-05	191	41	4	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PDZRN3 ADAM22	2.82e-05	191	41	4	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PDZRN3 ADAM22	2.82e-05	191	41	4	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBLN5 FBN1 LTBP4 PDZRN3	2.82e-05	191	41	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBN1 LTBP4 PDZRN4	2.82e-05	191	41	4	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBLN5 FBN1 LTBP4 PDZRN3	2.82e-05	191	41	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.82e-05	191	41	4	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.88e-05	192	41	4	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.88e-05	192	41	4	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.88e-05	192	41	4	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	droplet-Lung-nan-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 GAS6	2.88e-05	192	41	4	df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.88e-05	192	41	4	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN5 FBN1 LTBP4 PDZRN3	2.88e-05	192	41	4	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	2.88e-05	192	41	4	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.88e-05	192	41	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	2.94e-05	193	41	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LTBP4 TCAP PDZRN3 GAS6	2.94e-05	193	41	4	2b80991e7ba7640f7ab2139d30e4c54d8e533862
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 GAS6	2.94e-05	193	41	4	ac088c8f27b5b1888610e461ff45870ca60da886
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LTBP4 TCAP PDZRN3 GAS6	2.94e-05	193	41	4	90cfc34c2d0d7c70f071703d35db1d6037961481
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 GAS6	2.94e-05	193	41	4	92048d2e9e43513e6185e09553be3ee47d7e5207
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 PDZRN3	2.94e-05	193	41	4	80380358f44c2f4781676ec0f1fa94d4c69080d6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN5 FBN1 LTBP4 PDZRN3	3.00e-05	194	41	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	SAMHD1 FBLN5 FBN1 PDZRN4	3.00e-05	194	41	4	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LTBP4 PDZRN3 GAS6	3.00e-05	194	41	4	ca1f24070424b44b7a442e4fca761ebfbe24b063
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 PTEN LTBP4	3.00e-05	194	41	4	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 LTBP4 PDZRN4	3.00e-05	194	41	4	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	FBLN5 FBN1 LTBP4 PDZRN4	3.00e-05	194	41	4	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP4 TCAP PDZRN3 GAS6	3.06e-05	195	41	4	3f64e2313ec79a6d5f4013a52722d071172f6c5d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 LTBP4 PDZRN4	3.06e-05	195	41	4	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 FBN1 LTBP4 PDZRN4	3.06e-05	195	41	4	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN5 FBN1 LTBP4 PDZRN3	3.06e-05	195	41	4	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	Mesenchymal_cells\|World / Lineage and Cell class	FBLN5 FBN1 LTBP4 GAS6	3.06e-05	195	41	4	380eb436baa371f7aa2dc0c4a594afb173b5a25b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 FBN1 LTBP4 GAS6	3.06e-05	195	41	4	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP4 TCAP PDZRN3 GAS6	3.06e-05	195	41	4	d32716a12014522492becbde1088dc1106308490
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBLN5 FBN1 LTBP4 PDZRN3	3.06e-05	195	41	4	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBLN5 FBN1 LTBP4 PDZRN3	3.06e-05	195	41	4	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP4 TCAP PDZRN3 GAS6	3.06e-05	195	41	4	b913d5df50c88a3a255f516a1aa42419c6701e1e
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	FBLN5 FBN1 LTBP4 PDZRN3	3.06e-05	195	41	4	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP4 TCAP PDZRN3 GAS6	3.06e-05	195	41	4	7a5108335353ac160b684650c5da97d6f7f4dbcf
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 PDZRN3 PROS1	3.06e-05	195	41	4	223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	FBLN5 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN	3.12e-05	196	41	4	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCAP PDZRN3 GAS6 SLMAP	3.12e-05	196	41	4	5159d8625d80c20eb28157b2603c8bde9d377a35
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 FBN1 LTBP4 GAS6	3.12e-05	196	41	4	f47e551ba484687ba6ce8c29a085106131364042
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN5 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	Control-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	FBLN5 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	1ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 FBN1 LTBP4 GAS6	3.12e-05	196	41	4	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 FBLN5 FBN1 PTEN	3.12e-05	196	41	4	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	IPF-Stromal-Fibroblast\|IPF / Disease state, Lineage and Cell class	FBLN5 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCAP PDZRN3 GAS6 SLMAP	3.12e-05	196	41	4	6b5b7dbcb2cce8a736e44145a01290905876a5e9
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SAMHD1 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBLN5 FBN1 LTBP4 PDZRN3	3.12e-05	196	41	4	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	droplet-Bladder-nan-24m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAMHD1 FBLN5 FBN1 LTBP4	3.12e-05	196	41	4	83669ffdfe663885086571ccb0809f62aaba9752
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SAMHD1 FBLN5 FBN1 PDZRN4	3.12e-05	196	41	4	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 LTBP4 PDZRN3 PDZRN4	3.18e-05	197	41	4	2cb1f557ce1400398975de94638126b4522567f3
Computational	Metal / Ca ion binding.	FBN1 ADGRE1 LDLR GAS6	2.32e-04	133	25	4	MODULE_324
Drug	Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A	CCDC85C ADAM22 UBE3B GAS6 SOS2	2.04e-05	196	39	5	3204_DN
Drug	Epivincamine [6835-99-0]; Down 200; 11.2uM; PC3; HT_HG-U133A	HNF1B ANKMY1 ADAM22 MCM3AP SOS2	2.04e-05	196	39	5	4500_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A	TRIM45 CCDC85C ACTL8 MCM3AP SOS2	2.09e-05	197	39	5	3456_DN
Drug	Thioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; MCF7; HT_HG-U133A	CCDC85C ACTL8 LTBP4 ADAM22 GAS6	2.09e-05	197	39	5	4164_DN
Drug	Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; MCF7; HT_HG-U133A	HNF1B PRRG4 ACTL8 ADAM22 SOS2	2.19e-05	199	39	5	2232_UP
Drug	desmosine	FBLN5 FBN1 FBN3	1.03e-04	53	39	3	CID000025435
Drug	argatroban	ADGRE1 LDLR	1.28e-04	10	39	2	ctd:C031942
Drug	Rolitetracycline [751-97-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A	PRRG4 ACTL8 ADAM22 SOS2	2.78e-04	185	39	4	3369_DN
Drug	AC1LD8HW	DIAPH3 ACTL8 LDLR	2.88e-04	75	39	3	CID000644061
Drug	NOAC	LDLR PROS1	2.96e-04	15	39	2	CID000133043
Drug	Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A	CCDC85C LDLR GAS6 SOS2	3.01e-04	189	39	4	1700_UP
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	CCDC85C ACTL8 ADAM22 SOS2	3.20e-04	192	39	4	4395_DN
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	CCDC85C PRRG4 ADAM22 GAS6	3.20e-04	192	39	4	6054_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A	ANKMY1 PRRG4 ACTL8 PDZRN3	3.20e-04	192	39	4	2831_UP
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A	CCDC85C ZNF415 MCM3AP SOS2	3.20e-04	192	39	4	3804_DN
Drug	NSC226080	HNF1B FBN1 PTEN ACTL8 FBN3 PROS1 GAS6	3.23e-04	782	39	7	CID000005040
Drug	Theobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A	CCDC85C HNF1B ANKMY1 SOS2	3.26e-04	193	39	4	6613_DN
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A	PRRG4 ADAM22 MCM3AP SOS2	3.26e-04	193	39	4	4725_UP
Drug	Gramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A	TTC39A ADAM22 CCDC85B SOS2	3.26e-04	193	39	4	4118_UP
Drug	Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 LTBP4 SOS2	3.26e-04	193	39	4	5633_DN
Drug	Cyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A	TRIM45 CCDC85C ADAM22 SOS2	3.33e-04	194	39	4	4411_DN
Drug	alpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A	CCDC85C ZNF415 MCM3AP SOS2	3.33e-04	194	39	4	3795_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PRRG4 ACTL8 LTBP4 ADAM22	3.33e-04	194	39	4	3938_DN
Drug	STOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A	TRIM45 LTBP4 LDLR SOS2	3.33e-04	194	39	4	6380_DN
Drug	Cinchonine [118-10-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 PRRG4 LTBP4	3.33e-04	194	39	4	4107_DN
Drug	Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	ANKMY1 TTC39A ADAM22 GAS6	3.33e-04	194	39	4	2863_UP
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A	TTC39A LTBP4 ZNF415 ADAM22	3.33e-04	194	39	4	6031_UP
Drug	Mephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A	ANKMY1 ADAM22 GAS6 SOS2	3.39e-04	195	39	4	3580_DN
Drug	Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; MCF7; HT_HG-U133A	CCDC85C HNF1B ACTL8 SOS2	3.39e-04	195	39	4	4155_DN
Drug	Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A	ANKMY1 LTBP4 PDZRN3 ADAM22	3.39e-04	195	39	4	3942_DN
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A	TRIM45 CCDC85C LTBP4 ADAM22	3.39e-04	195	39	4	4742_DN
Drug	Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	PRRG4 LTBP4 UBE3B MCM3AP	3.39e-04	195	39	4	3191_DN
Drug	Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	TRIM45 TTC39A ZNF415 MCM3AP	3.39e-04	195	39	4	3718_DN
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ANKMY1 ACTL8 LDLR SOS2	3.39e-04	195	39	4	6224_UP
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A	DIAPH3 LTBP4 ADAM22 SOS2	3.46e-04	196	39	4	3817_UP
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A	ACTL8 PDZRN3 MCM3AP SOS2	3.46e-04	196	39	4	4148_DN
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A	PRRG4 TTC39A LTBP4 SOS2	3.46e-04	196	39	4	4808_UP
Drug	Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A	CCDC85C SAMHD1 PDZRN3 GAS6	3.46e-04	196	39	4	6273_DN
Drug	Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A	ANKMY1 FBN1 GAS6 SOS2	3.46e-04	196	39	4	2862_UP
Drug	Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A	HNF1B ACTL8 LTBP4 ADAM22	3.46e-04	196	39	4	4151_DN
Drug	Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A	LTBP4 UBE3B MCM3AP SOS2	3.46e-04	196	39	4	3167_DN
Drug	D-cycloserine [68-41-7]; Down 200; 39.2uM; MCF7; HT_HG-U133A	ANKMY1 SAMHD1 MCM3AP SOS2	3.46e-04	196	39	4	6782_DN
Drug	Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A	ANKMY1 SAMHD1 MCM3AP GAS6	3.46e-04	196	39	4	1511_DN
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A	ACTL8 LTBP4 ADAM22 SOS2	3.46e-04	196	39	4	6038_DN
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	HNF1B LTBP4 ZNF415 ADAM22	3.53e-04	197	39	4	3577_UP
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PRRG4 ACTL8 ADAM22 SOS2	3.53e-04	197	39	4	5692_DN
Drug	troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	ANKMY1 PRRG4 ZNF415 ADAM22	3.53e-04	197	39	4	6991_UP
Drug	Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 ACTL8 ADAM22	3.53e-04	197	39	4	3372_DN
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	CCDC85C ACTL8 ADAM22 MCM3AP	3.53e-04	197	39	4	3865_DN
Drug	Vigabatrin [60643-86-9]; Down 200; 31uM; MCF7; HT_HG-U133A	CCDC85C ACTL8 ADAM22 SOS2	3.53e-04	197	39	4	5415_DN
Drug	Ethionamide [536-33-4]; Up 200; 24uM; MCF7; HT_HG-U133A	TTC39A FBN1 LTBP4 ADAM22	3.53e-04	197	39	4	4418_UP
Drug	S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ANKMY1 PRRG4 ADAM22 SOS2	3.53e-04	197	39	4	5694_DN
Drug	Proadifen hydrochloride [62-68-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	CCDC85C ACTL8 MCM3AP GAS6	3.60e-04	198	39	4	3446_DN
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	FBN1 ADGRE1 LTBP4 ADAM22	3.60e-04	198	39	4	4414_UP
Drug	AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A	HNF1B FBN1 ADAM22 UBE3B	3.60e-04	198	39	4	6557_DN
Drug	Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A	HNF1B TTC39A ACTL8 LTBP4	3.60e-04	198	39	4	5446_UP
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	ACTL8 LTBP4 LDLR GAS6	3.60e-04	198	39	4	4805_DN
Drug	0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 PRRG4 SOS2	3.60e-04	198	39	4	7064_UP
Drug	copper(II) sulfate pentahydrate; Up 200; 100uM; ssMCF7; HG-U133A	ANKMY1 TTC39A ADAM22 MCM3AP	3.60e-04	198	39	4	500_UP
Drug	Bezafibrate [41859-67-0]; Down 200; 11uM; MCF7; HT_HG-U133A	LDLR UBE3B GAS6 SOS2	3.60e-04	198	39	4	4999_DN
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	PRRG4 SAMHD1 ACTL8 SOS2	3.60e-04	198	39	4	3294_DN
Drug	Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A	ANKMY1 PRRG4 ACTL8 ADAM22	3.60e-04	198	39	4	5673_DN
Drug	Benfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ACTL8 ADAM22 GAS6 SOS2	3.60e-04	198	39	4	6032_DN
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	CCDC85C ADAM22 MCM3AP SOS2	3.60e-04	198	39	4	3466_DN
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A	ANKMY1 ADAM22 MCM3AP SOS2	3.60e-04	198	39	4	3219_DN
Drug	Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HG-U133A	CCDC85C HNF1B SAMHD1 GAS6	3.60e-04	198	39	4	1924_UP
Drug	Gibberellic acid [77-06-5]; Up 200; 11.6uM; PC3; HT_HG-U133A	ZNF415 PDZRN3 ADAM22 CCDC85B	3.67e-04	199	39	4	4234_UP
Drug	Sulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 TTC39A MCM3AP	3.67e-04	199	39	4	3944_UP
Drug	Suramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A	TRIM45 ANKMY1 ACTL8 UBE3B	3.67e-04	199	39	4	7496_UP
Drug	Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A	CCDC85C PRRG4 ADGRE1 LTBP4	3.67e-04	199	39	4	3552_UP
Drug	Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A	PRRG4 ADAM22 MCM3AP SOS2	3.67e-04	199	39	4	3449_UP
Drug	ikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA	CCDC85C ANKMY1 PDZRN3 SOS2	3.67e-04	199	39	4	918_DN
Drug	Artemisinin [63968-64-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	SAMHD1 FBN1 LDLR GAS6	3.67e-04	199	39	4	7247_DN
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; MCF7; HT_HG-U133A	CCDC85C PRRG4 ADAM22 MCM3AP	3.67e-04	199	39	4	5006_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	ADGRE1 ZNF415 PDZRN3 SOS2	3.67e-04	199	39	4	5604_UP
Drug	Tribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	CCDC85C ADAM22 UBE3B SOS2	3.67e-04	199	39	4	3507_DN
Drug	Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A	HNF1B FBN1 ADAM22 SOS2	3.67e-04	199	39	4	5539_UP
Drug	genistein; Up 200; 1uM; MCF7; HG-U133A	HNF1B SAMHD1 ADAM22 SOS2	3.67e-04	199	39	4	268_UP
Drug	HA-1077 dihydrochloride; Down 200; 10uM; MCF7; HG-U133A	HNF1B ADGRE1 ADAM22 SOS2	3.67e-04	199	39	4	343_DN
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A	HNF1B ANKMY1 ZNF415 LDLR	3.74e-04	200	39	4	2077_UP
Drug	Sparteine (-) [90-39-1]; Down 200; 17uM; HL60; HT_HG-U133A	CCDC85C FBN1 GAS6 SOS2	3.74e-04	200	39	4	2134_DN
Drug	Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A	ANKMY1 PRRG4 ACTL8 MCM3AP	3.74e-04	200	39	4	3935_UP
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A	CCDC85C ANKMY1 FBN1 MCM3AP	3.74e-04	200	39	4	2648_UP
Drug	Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A	TTC39A LTBP4 ADAM22 SOS2	3.74e-04	200	39	4	3752_UP
Drug	dihydro-vitamin K1	PROS1 GAS6	3.83e-04	17	39	2	CID005189703
Drug	pifarnine	FBN1 LDLR	4.30e-04	18	39	2	CID006436032
Drug	Trenimon	FANCD2 HNF1B	4.80e-04	19	39	2	CID000006235
Disease	cutis laxa (implicated_via_orthology)	FBLN5 LTBP4	4.59e-06	3	37	2	DOID:3144 (implicated_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN3	4.59e-06	3	37	2	DOID:65 (implicated_via_orthology)
Disease	Cutis Laxa	FBLN5 LTBP4	2.29e-05	6	37	2	C0010495
Disease	Silicosis	PTEN PDZRN4	5.48e-05	9	37	2	C0037116
Disease	Thromboembolism	PROS1 GAS6	1.00e-04	12	37	2	C0040038
Disease	FEV/FEC ratio	SEC14L3 CCDC85C TTC39A FBN1 TTC7B LTBP4 PDZRN3 SLMAP	1.16e-04	1228	37	8	EFO_0004713
Disease	cortical surface area measurement	FBN1 DIAPH3 SETD3 PDZRN3 FBN3 MOV10 PDZRN4 SOS2	2.16e-04	1345	37	8	EFO_0010736
Disease	LEOPARD Syndrome	PTEN SOS2	3.48e-04	22	37	2	C0175704
Disease	hepatitis C (is_implicated_in)	SAMHD1 LDLR	5.67e-04	28	37	2	DOID:1883 (is_implicated_in)
Disease	fatty liver disease (implicated_via_orthology)	PTEN LDLR	6.95e-04	31	37	2	DOID:9452 (implicated_via_orthology)
Disease	testicular carcinoma	ACTL8 MCM3AP	1.16e-03	40	37	2	EFO_0005088

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAENRELRDLCCFLD	CCDC85B	71	Q15834
EDCDRRCLFQLETVA	ACTL8	191	Q9H568
TVCREAVNDCDIRET	ADAM22	501	Q9P0K1
FCCQQKERREEEDIE	DIAPH3	686	Q9NSV4
AQERNCTDIDECRIS	FBN3	1021	Q75N90
DECERFRELLELKCQ	PDZRN3	641	Q9UPQ7
DEDCERFRQLLELKC	PDZRN4	621	Q6ZMN7
ARCDARVENLQAECR	ANKRD36C	1616	Q5JPF3
AVETDQRVRVARCCE	MCM3AP	1196	O60318
RLQDDNQELRELCCF	CCDC85C	76	A6NKD9
NQELRELCCFLDDDR	CCDC85C	81	A6NKD9
REHEERLCEQEERLC	GOLGA6L3	251	A6NEY3
RLCEQEERLCEQEER	GOLGA6L3	256	A6NEY3
CEQEERLREQEERLC	GOLGA6L3	286	A6NEY3
HEERLCEQEERLCEQ	GOLGA6L4	246	A6NEF3
CEQEERLCEQEERLR	GOLGA6L4	251	A6NEF3
CEQEERLREQEERLC	GOLGA6L4	286	A6NEF3
QEERLCEQEERLCEQ	GOLGA6L9	211	A6NEM1
CEQEERLCEQEERLR	GOLGA6L9	216	A6NEM1
CEQEERLREQEERLC	GOLGA6L10	251	A6NI86
QEERLCEQEERLCEQ	GOLGA6L10	281	A6NI86
CEQEERLCEQEERLR	GOLGA6L10	286	A6NI86
EQEERLCEQEERLCE	GOLGA6L10	301	A6NI86
LCEQEERLCEQEERL	GOLGA6L10	306	A6NI86
ERLCEQEERLCEQEK	GOLGA6L10	311	A6NI86
CEQEERLREQEERLC	GOLGA6L19	251	H0YKK7
QEERLCEQEERLCEQ	GOLGA6L19	316	H0YKK7
CEQEERLCEQEERLC	GOLGA6L19	321	H0YKK7
RLCEQEERLCEQEER	GOLGA6L19	326	H0YKK7
EERLCEQEERLCEQE	GOLGA6L19	331	H0YKK7
EQEERLCEQEERLCE	GOLGA6L19	336	H0YKK7
LDSEERNCTDIDECR	FBN1	1061	P35555
LERECVEELCSREEA	GAS6	61	Q14393
CEREDDNKCARDIVR	ANKMY1	666	Q9P2S6
RRDVDECQLFRDQVC	LTBP4	1251	Q8N2S1
DDNRSCQDINECEHR	FBLN5	281	Q9UBX5
RDCERILHECDLQTE	SEC14L3	126	Q9UDX4
EAEQQRCCVLQEERD	CNTROB	321	Q8N137
RNCLLSCERLQDEEA	FANCD2	111	Q9BXW9
CDQEIDSICSIERAD	PTEN	296	P60484
REALVEECNRAECLQ	HNF1B	261	P35680
CARVRDADTNDRCQE	SYT3	21	Q9BQG1
DLCNDREVEKRCQTC	TRIM45	136	Q9H8W5
CSEEQEDRECLNQAI	SOS2	361	Q07890
LDTLREVCDDERDCI	PPP4R1	71	Q8TF05
EVCDDERDCIAVLER	PPP4R1	76	Q8TF05
CEVDNELRICARDKE	SAMHD1	341	Q9Y3Z3
LQACADVVDRERFCR	MOV10	751	Q9HCE1
EDDRCECVALQDFRA	SETD3	291	Q86TU7
LSCEVSEENCERREA	TCAP	6	O15273
RECIEELCNKEEARE	PROS1	56	P07225
DQGVECRDIDECRQD	ADGRE1	261	Q14246
CQQCEDQQREEATRL	SLMAP	641	Q14BN4
ERECNEELCNYEEAR	PRRG4	66	Q9BZD6
LRDQDRCRDVCESLE	UBE3B	291	Q7Z3V4
RVEIDQRCENRLECN	ZNF415	51	Q09FC8
ETEIERCRSECQWER	TTC7B	11	Q86TV6
IDAAIRRFEECCEAQ	TTC39A	331	Q5SRH9
LVAQRRCEDIDECQD	LDLR	346	P01130