| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | ATPase-coupled ion transmembrane transporter activity | 4.86e-09 | 24 | 18 | 4 | GO:0042625 | |
| GeneOntologyMolecularFunction | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism | 4.86e-09 | 24 | 18 | 4 | GO:0044769 | |
| GeneOntologyMolecularFunction | proton-transporting ATPase activity, rotational mechanism | 4.86e-09 | 24 | 18 | 4 | GO:0046961 | |
| GeneOntologyMolecularFunction | ATPase-coupled monoatomic cation transmembrane transporter activity | 2.50e-07 | 62 | 18 | 4 | GO:0019829 | |
| GeneOntologyMolecularFunction | ATPase binding | 2.34e-06 | 108 | 18 | 4 | GO:0051117 | |
| GeneOntologyMolecularFunction | ATPase-coupled transmembrane transporter activity | 2.42e-06 | 109 | 18 | 4 | GO:0042626 | |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 1.69e-05 | 178 | 18 | 4 | GO:0015399 | |
| GeneOntologyMolecularFunction | proton transmembrane transporter activity | 2.10e-05 | 188 | 18 | 4 | GO:0015078 | |
| GeneOntologyMolecularFunction | active monoatomic ion transmembrane transporter activity | 1.31e-04 | 301 | 18 | 4 | GO:0022853 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 7.54e-04 | 477 | 18 | 4 | GO:0022804 | |
| GeneOntologyMolecularFunction | ATP-dependent activity | 1.92e-03 | 614 | 18 | 4 | GO:0140657 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 2.07e-03 | 627 | 18 | 4 | GO:0022890 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 2.56e-03 | 664 | 18 | 4 | GO:0008324 | |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 4.12e-03 | 758 | 18 | 4 | GO:0015318 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 4.84e-03 | 793 | 18 | 4 | GO:0015075 | |
| GeneOntologyMolecularFunction | unfolded protein binding | 5.66e-03 | 126 | 18 | 2 | GO:0051082 | |
| GeneOntologyMolecularFunction | olfactory receptor activity | 6.40e-03 | 431 | 18 | 3 | GO:0004984 | |
| GeneOntologyBiologicalProcess | vacuolar acidification | 1.83e-08 | 36 | 17 | 4 | GO:0007035 | |
| GeneOntologyBiologicalProcess | intracellular pH reduction | 1.30e-07 | 58 | 17 | 4 | GO:0051452 | |
| GeneOntologyBiologicalProcess | regulation of intracellular pH | 9.20e-07 | 94 | 17 | 4 | GO:0051453 | |
| GeneOntologyBiologicalProcess | regulation of cellular pH | 1.23e-06 | 101 | 17 | 4 | GO:0030641 | |
| GeneOntologyBiologicalProcess | regulation of pH | 2.45e-06 | 120 | 17 | 4 | GO:0006885 | |
| GeneOntologyBiologicalProcess | proton transmembrane transport | 9.75e-06 | 170 | 17 | 4 | GO:1902600 | |
| GeneOntologyBiologicalProcess | synaptic vesicle lumen acidification | 1.20e-04 | 20 | 17 | 2 | GO:0097401 | |
| GeneOntologyBiologicalProcess | lysosomal lumen acidification | 1.75e-04 | 24 | 17 | 2 | GO:0007042 | |
| GeneOntologyBiologicalProcess | macroautophagy | 2.10e-04 | 374 | 17 | 4 | GO:0016236 | |
| GeneOntologyBiologicalProcess | synaptic vesicle maturation | 2.56e-04 | 29 | 17 | 2 | GO:0016188 | |
| GeneOntologyBiologicalProcess | regulation of lysosomal lumen pH | 3.13e-04 | 32 | 17 | 2 | GO:0035751 | |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | 6.97e-04 | 922 | 17 | 5 | GO:0098662 | |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | 7.68e-04 | 942 | 17 | 5 | GO:0098655 | |
| GeneOntologyBiologicalProcess | vacuole organization | 1.04e-03 | 249 | 17 | 3 | GO:0007033 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | 1.09e-03 | 1017 | 17 | 5 | GO:0098660 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | 1.33e-03 | 611 | 17 | 4 | GO:0030003 | |
| GeneOntologyBiologicalProcess | sensory perception | 1.38e-03 | 1072 | 17 | 5 | GO:0007600 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | 1.43e-03 | 622 | 17 | 4 | GO:0006873 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | 1.64e-03 | 1115 | 17 | 5 | GO:0034220 | |
| GeneOntologyBiologicalProcess | process utilizing autophagic mechanism | 1.68e-03 | 650 | 17 | 4 | GO:0061919 | |
| GeneOntologyBiologicalProcess | autophagy | 1.68e-03 | 650 | 17 | 4 | GO:0006914 | |
| GeneOntologyBiologicalProcess | monoatomic cation transport | 1.93e-03 | 1157 | 17 | 5 | GO:0006812 | |
| GeneOntologyBiologicalProcess | neuron cellular homeostasis | 2.14e-03 | 84 | 17 | 2 | GO:0070050 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | 2.26e-03 | 705 | 17 | 4 | GO:0055080 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | 2.40e-03 | 717 | 17 | 4 | GO:0050801 | |
| GeneOntologyBiologicalProcess | regulation of autophagy | 4.02e-03 | 400 | 17 | 3 | GO:0010506 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | 4.10e-03 | 1374 | 17 | 5 | GO:0006811 | |
| GeneOntologyBiologicalProcess | lytic vacuole organization | 4.24e-03 | 119 | 17 | 2 | GO:0080171 | |
| GeneOntologyBiologicalProcess | lysosome organization | 4.24e-03 | 119 | 17 | 2 | GO:0007040 | |
| GeneOntologyBiologicalProcess | autophagosome assembly | 4.38e-03 | 121 | 17 | 2 | GO:0000045 | |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | 4.74e-03 | 866 | 17 | 4 | GO:0055082 | |
| GeneOntologyBiologicalProcess | autophagosome organization | 4.96e-03 | 129 | 17 | 2 | GO:1905037 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | 4.99e-03 | 432 | 17 | 3 | GO:0050911 | |
| GeneOntologyBiologicalProcess | sensory perception of smell | 6.12e-03 | 465 | 17 | 3 | GO:0007608 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | 6.87e-03 | 485 | 17 | 3 | GO:0050907 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | 7.36e-03 | 981 | 17 | 4 | GO:0019725 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | 8.50e-03 | 524 | 17 | 3 | GO:0009593 | |
| GeneOntologyCellularComponent | vacuolar proton-transporting V-type ATPase, V0 domain | 8.05e-11 | 10 | 18 | 4 | GO:0000220 | |
| GeneOntologyCellularComponent | proton-transporting V-type ATPase, V0 domain | 1.90e-10 | 12 | 18 | 4 | GO:0033179 | |
| GeneOntologyCellularComponent | proton-transporting two-sector ATPase complex, proton-transporting domain | 5.68e-09 | 26 | 18 | 4 | GO:0033177 | |
| GeneOntologyCellularComponent | vacuolar proton-transporting V-type ATPase complex | 5.68e-09 | 26 | 18 | 4 | GO:0016471 | |
| GeneOntologyCellularComponent | proton-transporting V-type ATPase complex | 9.02e-09 | 29 | 18 | 4 | GO:0033176 | |
| GeneOntologyCellularComponent | cation-transporting ATPase complex | 7.96e-08 | 49 | 18 | 4 | GO:0090533 | |
| GeneOntologyCellularComponent | proton-transporting two-sector ATPase complex | 1.10e-07 | 53 | 18 | 4 | GO:0016469 | |
| GeneOntologyCellularComponent | ATPase dependent transmembrane transport complex | 1.28e-07 | 55 | 18 | 4 | GO:0098533 | |
| GeneOntologyCellularComponent | phagocytic vesicle membrane | 6.78e-07 | 83 | 18 | 4 | GO:0030670 | |
| GeneOntologyCellularComponent | ATPase complex | 3.96e-06 | 129 | 18 | 4 | GO:1904949 | |
| GeneOntologyCellularComponent | phagocytic vesicle | 8.63e-06 | 157 | 18 | 4 | GO:0045335 | |
| GeneOntologyCellularComponent | endocytic vesicle membrane | 2.81e-05 | 212 | 18 | 4 | GO:0030666 | |
| GeneOntologyCellularComponent | endocytic vesicle | 2.80e-04 | 384 | 18 | 4 | GO:0030139 | |
| GeneOntologyCellularComponent | lysosome | 4.88e-04 | 811 | 18 | 5 | GO:0005764 | |
| GeneOntologyCellularComponent | lytic vacuole | 4.88e-04 | 811 | 18 | 5 | GO:0000323 | |
| GeneOntologyCellularComponent | lysosomal membrane | 5.63e-04 | 462 | 18 | 4 | GO:0005765 | |
| GeneOntologyCellularComponent | lytic vacuole membrane | 5.63e-04 | 462 | 18 | 4 | GO:0098852 | |
| GeneOntologyCellularComponent | vacuolar membrane | 7.98e-04 | 507 | 18 | 4 | GO:0005774 | |
| GeneOntologyCellularComponent | vacuole | 8.37e-04 | 913 | 18 | 5 | GO:0005773 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | 8.97e-04 | 523 | 18 | 4 | GO:1902495 | |
| GeneOntologyCellularComponent | transporter complex | 1.08e-03 | 550 | 18 | 4 | GO:1990351 | |
| GeneOntologyCellularComponent | ficolin-1-rich granule membrane | 1.24e-03 | 61 | 18 | 2 | GO:0101003 | |
| GeneOntologyCellularComponent | endosome membrane | 1.51e-03 | 602 | 18 | 4 | GO:0010008 | |
| GeneOntologyCellularComponent | secretory vesicle | 3.33e-03 | 1246 | 18 | 5 | GO:0099503 | |
| GeneOntologyCellularComponent | apical plasma membrane | 7.90e-03 | 487 | 18 | 3 | GO:0016324 | |
| GeneOntologyCellularComponent | tertiary granule | 8.62e-03 | 164 | 18 | 2 | GO:0070820 | |
| GeneOntologyCellularComponent | secretory granule | 9.76e-03 | 1014 | 18 | 4 | GO:0030141 | |
| GeneOntologyCellularComponent | exocytic vesicle membrane | 1.02e-02 | 179 | 18 | 2 | GO:0099501 | |
| GeneOntologyCellularComponent | synaptic vesicle membrane | 1.02e-02 | 179 | 18 | 2 | GO:0030672 | |
| GeneOntologyCellularComponent | ficolin-1-rich granule | 1.09e-02 | 185 | 18 | 2 | GO:0101002 | |
| GeneOntologyCellularComponent | apical part of cell | 1.34e-02 | 592 | 18 | 3 | GO:0045177 | |
| GeneOntologyCellularComponent | endosome | 1.58e-02 | 1167 | 18 | 4 | GO:0005768 | |
| HumanPheno | Reduced bone mineral density | 1.32e-05 | 578 | 7 | 6 | HP:0004349 | |
| HumanPheno | Abnormality of bone mineral density | 1.05e-04 | 822 | 7 | 6 | HP:0004348 | |
| HumanPheno | Abnormal bone ossification | 1.09e-04 | 827 | 7 | 6 | HP:0011849 | |
| HumanPheno | Abnormal bone structure | 1.57e-04 | 881 | 7 | 6 | HP:0003330 | |
| HumanPheno | Slender long bone | 1.72e-04 | 89 | 7 | 3 | HP:0003100 | |
| HumanPheno | Gracile long bones | 1.72e-04 | 89 | 7 | 3 | HP:0003061 | |
| MousePheno | no spontaneous movement | 1.80e-06 | 123 | 11 | 4 | MP:0001404 | |
| MousePheno | abnormal hippocampus CA3 region morphology | 1.06e-04 | 20 | 11 | 2 | MP:0008267 | |
| MousePheno | increased freezing behavior | 1.17e-04 | 128 | 11 | 3 | MP:0020421 | |
| MousePheno | abnormal cochlear endolymph physiology | 1.54e-04 | 24 | 11 | 2 | MP:0006390 | |
| MousePheno | abnormal endocochlear potential | 1.54e-04 | 24 | 11 | 2 | MP:0002630 | |
| MousePheno | abnormal endolymph physiology | 1.67e-04 | 25 | 11 | 2 | MP:0004885 | |
| MousePheno | abnormal freezing behavior | 2.40e-04 | 163 | 11 | 3 | MP:0020420 | |
| MousePheno | facial cleft | 5.72e-04 | 46 | 11 | 2 | MP:0008797 | |
| MousePheno | abnormal hippocampus region morphology | 7.03e-04 | 51 | 11 | 2 | MP:0008262 | |
| MousePheno | abnormal Ammon gyrus morphology | 8.17e-04 | 55 | 11 | 2 | MP:0000815 | |
| MousePheno | increased bone mineral content | 9.19e-04 | 258 | 11 | 3 | MP:0010123 | |
| MousePheno | abnormal lysosome morphology | 1.00e-03 | 61 | 11 | 2 | MP:0005058 | |
| MousePheno | abnormal vacuole morphology | 1.17e-03 | 66 | 11 | 2 | MP:0020851 | |
| MousePheno | cleft palate | 1.28e-03 | 289 | 11 | 3 | MP:0000111 | |
| MousePheno | oral cleft | 1.30e-03 | 291 | 11 | 3 | MP:0021164 | |
| MousePheno | abnormal mouth morphology | 1.32e-03 | 670 | 11 | 4 | MP:0000452 | |
| Domain | V-type_ATPase_116kDa_su_euka | 6.04e-13 | 4 | 18 | 4 | IPR026028 | |
| Domain | V_ATPase_I | 6.04e-13 | 4 | 18 | 4 | PF01496 | |
| Domain | V-ATPase_116kDa_su | 6.04e-13 | 4 | 18 | 4 | IPR002490 | |
| Domain | HSP40/DnaJ_pept-bd | 3.15e-05 | 9 | 18 | 2 | IPR008971 | |
| Domain | DnaJ_C | 3.15e-05 | 9 | 18 | 2 | IPR002939 | |
| Domain | DnaJ_C | 3.15e-05 | 9 | 18 | 2 | PF01556 | |
| Domain | DnaJ_domain_CS | 3.04e-04 | 27 | 18 | 2 | IPR018253 | |
| Domain | DnaJ | 9.64e-04 | 48 | 18 | 2 | PF00226 | |
| Domain | DnaJ | 1.00e-03 | 49 | 18 | 2 | SM00271 | |
| Domain | DNAJ_1 | 1.00e-03 | 49 | 18 | 2 | PS00636 | |
| Domain | DNAJ_2 | 1.00e-03 | 49 | 18 | 2 | PS50076 | |
| Domain | - | 1.00e-03 | 49 | 18 | 2 | 1.10.287.110 | |
| Domain | DnaJ_domain | 1.09e-03 | 51 | 18 | 2 | IPR001623 | |
| Domain | Prefoldin | 2.15e-03 | 72 | 18 | 2 | IPR009053 | |
| Domain | Olfact_rcpt | 5.96e-03 | 393 | 18 | 3 | IPR000725 | |
| Domain | GPCR_Rhodpsn_7TM | 2.51e-02 | 670 | 18 | 3 | IPR017452 | |
| Domain | 7tm_1 | 2.58e-02 | 677 | 18 | 3 | PF00001 | |
| Domain | G_PROTEIN_RECEP_F1_1 | 2.66e-02 | 685 | 18 | 3 | PS00237 | |
| Domain | G_PROTEIN_RECEP_F1_2 | 2.72e-02 | 691 | 18 | 3 | PS50262 | |
| Domain | GPCR_Rhodpsn | 2.73e-02 | 692 | 18 | 3 | IPR000276 | |
| Pathway | REACTOME_INSULIN_RECEPTOR_RECYCLING | 1.64e-08 | 30 | 14 | 4 | M506 | |
| Pathway | REACTOME_INSULIN_RECEPTOR_RECYCLING | 1.89e-08 | 31 | 14 | 4 | MM15467 | |
| Pathway | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | 1.89e-08 | 31 | 14 | 4 | MM15639 | |
| Pathway | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | 1.89e-08 | 31 | 14 | 4 | M991 | |
| Pathway | REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES | 3.52e-08 | 36 | 14 | 4 | M26923 | |
| Pathway | REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES | 4.41e-08 | 38 | 14 | 4 | MM14519 | |
| Pathway | KEGG_LYSOSOME | 8.07e-08 | 121 | 14 | 5 | M11266 | |
| Pathway | KEGG_VIBRIO_CHOLERAE_INFECTION | 1.87e-07 | 54 | 14 | 4 | M17906 | |
| Pathway | REACTOME_IRON_UPTAKE_AND_TRANSPORT | 2.17e-07 | 56 | 14 | 4 | MM15638 | |
| Pathway | REACTOME_IRON_UPTAKE_AND_TRANSPORT | 2.50e-07 | 58 | 14 | 4 | M962 | |
| Pathway | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | 4.78e-07 | 68 | 14 | 4 | M16848 | |
| Pathway | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | 7.49e-07 | 76 | 14 | 4 | MM15442 | |
| Pathway | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | 1.02e-06 | 82 | 14 | 4 | M1021 | |
| Pathway | KEGG_OXIDATIVE_PHOSPHORYLATION | 6.84e-06 | 132 | 14 | 4 | M19540 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 2.13e-05 | 176 | 14 | 4 | MM15718 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 2.48e-05 | 183 | 14 | 4 | M997 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 3.60e-04 | 681 | 14 | 5 | MM14985 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 5.16e-04 | 736 | 14 | 5 | M27287 | |
| Pathway | REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES | 6.02e-04 | 418 | 14 | 4 | MM15587 | |
| Pathway | REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES | 1.48e-03 | 532 | 14 | 4 | M27870 | |
| Pathway | REACTOME_INNATE_IMMUNE_SYSTEM | 2.03e-03 | 995 | 14 | 5 | MM14661 | |
| Pathway | REACTOME_INNATE_IMMUNE_SYSTEM | 3.53e-03 | 1128 | 14 | 5 | M1036 | |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | 6.05e-03 | 389 | 14 | 3 | M14091 | |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | 7.34e-03 | 417 | 14 | 3 | M4072 | |
| Pathway | REACTOME_NEUTROPHIL_DEGRANULATION | 1.07e-02 | 478 | 14 | 3 | M27620 | |
| Pathway | REACTOME_NEUTROPHIL_DEGRANULATION | 1.28e-02 | 511 | 14 | 3 | MM15330 | |
| Pathway | REACTOME_SENSORY_PERCEPTION | 2.29e-02 | 636 | 14 | 3 | M41834 | |
| Pubmed | 5.02e-14 | 4 | 18 | 4 | 17595521 | ||
| Pubmed | 2.51e-13 | 5 | 18 | 4 | 35948619 | ||
| Pubmed | Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. | 7.53e-13 | 6 | 18 | 4 | 21307348 | |
| Pubmed | 1.76e-12 | 7 | 18 | 4 | 20711468 | ||
| Pubmed | 3.58e-11 | 13 | 18 | 4 | 32001091 | ||
| Pubmed | 1.16e-10 | 3 | 18 | 3 | 10722719 | ||
| Pubmed | 1.16e-10 | 3 | 18 | 3 | 12672822 | ||
| Pubmed | 1.16e-10 | 3 | 18 | 3 | 10702241 | ||
| Pubmed | 1.16e-10 | 3 | 18 | 3 | 24072707 | ||
| Pubmed | Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. | 1.19e-10 | 17 | 18 | 4 | 33065002 | |
| Pubmed | 3.65e-10 | 22 | 18 | 4 | 12788495 | ||
| Pubmed | The vacuolar (H+)-ATPases--nature's most versatile proton pumps. | 3.65e-10 | 22 | 18 | 4 | 11836511 | |
| Pubmed | Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes. | 3.65e-10 | 22 | 18 | 4 | 14580332 | |
| Pubmed | Neurotransmitter release: the dark side of the vacuolar-H+ATPase. | 3.65e-10 | 22 | 18 | 4 | 14597263 | |
| Pubmed | 3.65e-10 | 22 | 18 | 4 | 17662945 | ||
| Pubmed | 4.65e-10 | 4 | 18 | 3 | 17497178 | ||
| Pubmed | Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor. | 6.31e-10 | 25 | 18 | 4 | 2874839 | |
| Pubmed | Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification. | 4.07e-09 | 7 | 18 | 3 | 19549681 | |
| Pubmed | The vacuolar H+-ATPase: a universal proton pump of eukaryotes. | 9.45e-08 | 18 | 18 | 3 | 9210392 | |
| Pubmed | Animal plasma membrane energization by proton-motive V-ATPases. | 9.45e-08 | 18 | 18 | 3 | 10440860 | |
| Pubmed | 9.45e-08 | 18 | 18 | 3 | 10340843 | ||
| Pubmed | 9.45e-08 | 18 | 18 | 3 | 10224039 | ||
| Pubmed | Vacuolar and plasma membrane proton-adenosinetriphosphatases. | 9.45e-08 | 18 | 18 | 3 | 10221984 | |
| Pubmed | Structure, function and regulation of the vacuolar (H+)-ATPase. | 1.12e-07 | 19 | 18 | 3 | 9442887 | |
| Pubmed | The mutational spectrum of human malignant autosomal recessive osteopetrosis. | 2.53e-07 | 2 | 18 | 2 | 11532986 | |
| Pubmed | 7.59e-07 | 3 | 18 | 2 | 15800125 | ||
| Pubmed | 7.59e-07 | 3 | 18 | 2 | 23288846 | ||
| Pubmed | The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans. | 7.59e-07 | 3 | 18 | 2 | 12649290 | |
| Pubmed | V1 and V0 domains of the human H+-ATPase are linked by an interaction between the G and a subunits. | 1.52e-06 | 4 | 18 | 2 | 17360703 | |
| Pubmed | a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a. | 2.53e-06 | 5 | 18 | 2 | 11498539 | |
| Pubmed | Protein Binder Toolbox for Studies of Solute Carrier Transporters. | 3.17e-06 | 56 | 18 | 3 | 38878854 | |
| Pubmed | 5.77e-06 | 235 | 18 | 4 | 32614325 | ||
| Pubmed | 3.42e-05 | 17 | 18 | 2 | 28793259 | ||
| Pubmed | 3.64e-05 | 126 | 18 | 3 | 17897319 | ||
| Pubmed | A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. | 4.29e-05 | 392 | 18 | 4 | 33144569 | |
| Pubmed | 4.30e-05 | 19 | 18 | 2 | 16177003 | ||
| Pubmed | 4.78e-05 | 20 | 18 | 2 | 22982048 | ||
| Pubmed | Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. | 5.71e-05 | 422 | 18 | 4 | 27342126 | |
| Pubmed | 5.81e-05 | 22 | 18 | 2 | 11147971 | ||
| Pubmed | 6.94e-05 | 24 | 18 | 2 | 23085658 | ||
| Pubmed | 8.16e-05 | 26 | 18 | 2 | 35961308 | ||
| Interaction | VMA21 interactions | 1.84e-08 | 110 | 16 | 5 | int:VMA21 | |
| Interaction | CYTH2 interactions | 1.02e-07 | 57 | 16 | 4 | int:CYTH2 | |
| Interaction | ATP6V0D2 interactions | 1.64e-07 | 64 | 16 | 4 | int:ATP6V0D2 | |
| Interaction | CCDC115 interactions | 9.53e-07 | 99 | 16 | 4 | int:CCDC115 | |
| Interaction | ATP6V1C1 interactions | 1.12e-06 | 103 | 16 | 4 | int:ATP6V1C1 | |
| Interaction | ATP6V1D interactions | 1.12e-06 | 103 | 16 | 4 | int:ATP6V1D | |
| Interaction | ATP6V1B1 interactions | 2.06e-06 | 120 | 16 | 4 | int:ATP6V1B1 | |
| Interaction | ATP6V1E1 interactions | 2.27e-06 | 123 | 16 | 4 | int:ATP6V1E1 | |
| Interaction | ATP6V1F interactions | 2.50e-06 | 126 | 16 | 4 | int:ATP6V1F | |
| Interaction | ATP6V0A2 interactions | 2.92e-06 | 131 | 16 | 4 | int:ATP6V0A2 | |
| Interaction | ATP6V0C interactions | 3.49e-06 | 137 | 16 | 4 | int:ATP6V0C | |
| Interaction | TMEM199 interactions | 3.81e-06 | 140 | 16 | 4 | int:TMEM199 | |
| Interaction | ATP6AP1 interactions | 3.81e-06 | 140 | 16 | 4 | int:ATP6AP1 | |
| Interaction | ATP6V1G2 interactions | 4.97e-06 | 43 | 16 | 3 | int:ATP6V1G2 | |
| Interaction | ATP6V0D1 interactions | 1.15e-05 | 185 | 16 | 4 | int:ATP6V0D1 | |
| Interaction | EMC1 interactions | 1.36e-05 | 418 | 16 | 5 | int:EMC1 | |
| Interaction | RNF128 interactions | 1.91e-05 | 67 | 16 | 3 | int:RNF128 | |
| Interaction | MS4A12 interactions | 2.12e-05 | 9 | 16 | 2 | int:MS4A12 | |
| Interaction | TCIRG1 interactions | 2.37e-05 | 72 | 16 | 3 | int:TCIRG1 | |
| Interaction | ATP6V1B2 interactions | 3.09e-05 | 238 | 16 | 4 | int:ATP6V1B2 | |
| Interaction | AQP5 interactions | 3.88e-05 | 12 | 16 | 2 | int:AQP5 | |
| Interaction | TAP2 interactions | 5.27e-05 | 94 | 16 | 3 | int:TAP2 | |
| Interaction | ATP6AP2 interactions | 8.21e-05 | 306 | 16 | 4 | int:ATP6AP2 | |
| Interaction | KIAA2013 interactions | 9.85e-05 | 116 | 16 | 3 | int:KIAA2013 | |
| Interaction | SLC12A6 interactions | 1.20e-04 | 124 | 16 | 3 | int:SLC12A6 | |
| Interaction | CDC42EP1 interactions | 1.41e-04 | 131 | 16 | 3 | int:CDC42EP1 | |
| Interaction | TTC9C interactions | 1.58e-04 | 136 | 16 | 3 | int:TTC9C | |
| Interaction | NPC1 interactions | 1.60e-04 | 364 | 16 | 4 | int:NPC1 | |
| Interaction | FOXJ1 interactions | 1.90e-04 | 26 | 16 | 2 | int:FOXJ1 | |
| Interaction | DNASE2 interactions | 1.90e-04 | 26 | 16 | 2 | int:DNASE2 | |
| Interaction | ATP6V0A4 interactions | 2.21e-04 | 28 | 16 | 2 | int:ATP6V0A4 | |
| Interaction | TUBD1 interactions | 2.54e-04 | 30 | 16 | 2 | int:TUBD1 | |
| Interaction | METTL23 interactions | 2.54e-04 | 30 | 16 | 2 | int:METTL23 | |
| Interaction | MUC1 interactions | 2.94e-04 | 168 | 16 | 3 | int:MUC1 | |
| Interaction | SLC14A1 interactions | 3.08e-04 | 33 | 16 | 2 | int:SLC14A1 | |
| Interaction | ATP6V0E1 interactions | 3.46e-04 | 35 | 16 | 2 | int:ATP6V0E1 | |
| Interaction | ATP6V0A1 interactions | 3.49e-04 | 178 | 16 | 3 | int:ATP6V0A1 | |
| Interaction | HPS5 interactions | 3.66e-04 | 36 | 16 | 2 | int:HPS5 | |
| Interaction | EDEM1 interactions | 5.05e-04 | 202 | 16 | 3 | int:EDEM1 | |
| Interaction | SFT2D1 interactions | 5.24e-04 | 43 | 16 | 2 | int:SFT2D1 | |
| Interaction | ARRDC5 interactions | 5.24e-04 | 43 | 16 | 2 | int:ARRDC5 | |
| Interaction | SLC25A30 interactions | 5.48e-04 | 44 | 16 | 2 | int:SLC25A30 | |
| Interaction | FAM131B interactions | 5.99e-04 | 46 | 16 | 2 | int:FAM131B | |
| Interaction | BCAM interactions | 7.08e-04 | 50 | 16 | 2 | int:BCAM | |
| Interaction | SLC34A2 interactions | 7.08e-04 | 50 | 16 | 2 | int:SLC34A2 | |
| Interaction | PSEN1 interactions | 7.09e-04 | 227 | 16 | 3 | int:PSEN1 | |
| Interaction | PLPP4 interactions | 7.37e-04 | 51 | 16 | 2 | int:PLPP4 | |
| Interaction | CTSL interactions | 8.33e-04 | 240 | 16 | 3 | int:CTSL | |
| Interaction | SERINC2 interactions | 8.56e-04 | 55 | 16 | 2 | int:SERINC2 | |
| Interaction | MAP2K3 interactions | 9.48e-04 | 251 | 16 | 3 | int:MAP2K3 | |
| Interaction | FZD10 interactions | 1.23e-03 | 66 | 16 | 2 | int:FZD10 | |
| Interaction | AGPAT2 interactions | 1.27e-03 | 67 | 16 | 2 | int:AGPAT2 | |
| Interaction | EMP3 interactions | 1.34e-03 | 69 | 16 | 2 | int:EMP3 | |
| Interaction | TANGO6 interactions | 1.42e-03 | 71 | 16 | 2 | int:TANGO6 | |
| Interaction | GPRC5D interactions | 1.46e-03 | 72 | 16 | 2 | int:GPRC5D | |
| Interaction | TMEM231 interactions | 1.54e-03 | 74 | 16 | 2 | int:TMEM231 | |
| Interaction | PCSK9 interactions | 1.59e-03 | 75 | 16 | 2 | int:PCSK9 | |
| Interaction | HSPA6 interactions | 1.76e-03 | 311 | 16 | 3 | int:HSPA6 | |
| Interaction | MTO1 interactions | 1.85e-03 | 81 | 16 | 2 | int:MTO1 | |
| Interaction | ACP2 interactions | 1.94e-03 | 83 | 16 | 2 | int:ACP2 | |
| Interaction | MAN2B1 interactions | 2.08e-03 | 86 | 16 | 2 | int:MAN2B1 | |
| Interaction | ATP11C interactions | 2.13e-03 | 87 | 16 | 2 | int:ATP11C | |
| Interaction | TMEM185A interactions | 2.13e-03 | 87 | 16 | 2 | int:TMEM185A | |
| Interaction | TCTN3 interactions | 2.15e-03 | 334 | 16 | 3 | int:TCTN3 | |
| Cytoband | 11q12.1 | 1.80e-03 | 161 | 18 | 2 | 11q12.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q12 | 7.96e-03 | 345 | 18 | 2 | chr11q12 | |
| GeneFamily | V-type ATPases | 2.69e-09 | 23 | 15 | 4 | 415 | |
| GeneFamily | Olfactory receptors, family 4 | 1.52e-04 | 129 | 15 | 3 | 151 | |
| GeneFamily | DNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing | 7.39e-04 | 49 | 15 | 2 | 584 | |
| Drug | WIN 52035 | 4.14e-09 | 5 | 18 | 3 | CID000001786 | |
| Drug | Na-Z | 8.49e-09 | 31 | 18 | 4 | CID005497094 | |
| Drug | MoO2 | 6.68e-08 | 51 | 18 | 4 | CID000029320 | |
| Drug | AC1MC4XW | 5.47e-07 | 21 | 18 | 3 | CID002724447 | |
| Drug | 6-carboxyfluorescein diacetate | 1.66e-06 | 30 | 18 | 3 | CID000151095 | |
| Drug | AC1OCACR | 2.44e-06 | 34 | 18 | 3 | CID006914630 | |
| Drug | ClNCO | 3.54e-06 | 4 | 18 | 2 | CID000139629 | |
| Drug | Ph-F | 4.38e-06 | 144 | 18 | 4 | CID000447564 | |
| Drug | AMPCP | 4.67e-06 | 42 | 18 | 3 | CID000004798 | |
| Drug | vanadium | 5.02e-06 | 149 | 18 | 4 | CID000023990 | |
| Drug | NSC381866 | 8.27e-06 | 169 | 18 | 4 | CID000002287 | |
| Drug | NF T | 1.31e-05 | 190 | 18 | 4 | CID006436102 | |
| Drug | A4-1 | 1.65e-05 | 8 | 18 | 2 | CID006102684 | |
| Drug | AC1L1G92 | 1.65e-05 | 8 | 18 | 2 | CID000003582 | |
| Drug | nordiazepam | 1.68e-05 | 64 | 18 | 3 | CID000002997 | |
| Drug | p-azophenylarsonate | 3.23e-05 | 11 | 18 | 2 | CID000023749 | |
| Drug | Lndfh-ii | 3.23e-05 | 11 | 18 | 2 | CID000124919 | |
| Drug | AC1NRA2O | 3.80e-05 | 84 | 18 | 3 | CID005287668 | |
| Drug | A-52 | 3.88e-05 | 12 | 18 | 2 | CID000120355 | |
| Drug | HCNO | 3.88e-05 | 12 | 18 | 2 | CID000521293 | |
| Drug | nitrogen peroxide | 6.16e-05 | 15 | 18 | 2 | CID003032552 | |
| Drug | NSC643699 | 7.04e-05 | 16 | 18 | 2 | CID000370474 | |
| Drug | hydroxymethyltrioxsalen | 7.04e-05 | 16 | 18 | 2 | CID000104953 | |
| Drug | AC1L8NTU | 8.04e-05 | 108 | 18 | 3 | CID000384608 | |
| Drug | oxovanadium | 1.10e-04 | 120 | 18 | 3 | CID000024411 | |
| Drug | L-cysteine methyl ester | 1.23e-04 | 21 | 18 | 2 | CID000004040 | |
| Drug | AC1MHDI0 | 1.35e-04 | 22 | 18 | 2 | CID003000984 | |
| Drug | dihydroflavonol | 1.48e-04 | 23 | 18 | 2 | CID000147806 | |
| Drug | Chlorocruorin | 1.75e-04 | 25 | 18 | 2 | CID005748247 | |
| Drug | AC1OCACU | 2.05e-04 | 27 | 18 | 2 | CID006914631 | |
| Drug | hypoiodite | 2.20e-04 | 28 | 18 | 2 | CID000123340 | |
| Drug | AC1O581Q | 2.37e-04 | 29 | 18 | 2 | CID006453768 | |
| Drug | L-thiocitrulline | 2.53e-04 | 30 | 18 | 2 | CID002733514 | |
| Drug | propan | 3.07e-04 | 33 | 18 | 2 | CID000006334 | |
| Drug | I-DOX | 3.26e-04 | 34 | 18 | 2 | CID000108161 | |
| Drug | AC1NRB3N | 3.87e-04 | 37 | 18 | 2 | CID005288242 | |
| Drug | FR-3 | 3.87e-04 | 37 | 18 | 2 | CID000447341 | |
| Drug | N,N,N',N'-tetramethyl-p-phenylenediamine | 4.30e-04 | 39 | 18 | 2 | CID000007490 | |
| Drug | MAPS | 4.32e-04 | 191 | 18 | 3 | CID000066161 | |
| Drug | Thioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; PC3; HG-U133A | 4.52e-04 | 194 | 18 | 3 | 1905_DN | |
| Drug | Zm241385 | 5.23e-04 | 43 | 18 | 2 | CID005311506 | |
| Drug | guanidine-3-propanol | 5.48e-04 | 44 | 18 | 2 | CID000448503 | |
| Drug | nitrosonium | 5.48e-04 | 44 | 18 | 2 | CID000084878 | |
| Drug | AC1L1I0G | 5.99e-04 | 46 | 18 | 2 | CID000004370 | |
| Drug | glycyl-dl-alanine | 6.52e-04 | 48 | 18 | 2 | CID000098153 | |
| Drug | funiferine N-oxide | 6.79e-04 | 49 | 18 | 2 | CID000191631 | |
| Drug | uranium | 9.67e-04 | 252 | 18 | 3 | CID000023989 | |
| Disease | autosomal recessive osteopetrosis 1 (implicated_via_orthology) | 3.77e-13 | 5 | 17 | 4 | DOID:0110942 (implicated_via_orthology) | |
| Disease | renal tubular acidosis (implicated_via_orthology) | 5.27e-12 | 8 | 17 | 4 | DOID:14219 (implicated_via_orthology) | |
| Disease | obsolete aging | 1.10e-02 | 279 | 17 | 2 | GO_0007568 | |
| Disease | mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement | 1.50e-02 | 328 | 17 | 2 | EFO_0008377, EFO_0008378 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| FPHGGGFVLAFEFML | 71 | Q8IZL9 | |
| FFYFTHIDAGMFGVF | 286 | Q9H7Y0 | |
| IFFFHFLGGAMVFFL | 101 | P58180 | |
| FFFFGPIMTFDRFHA | 216 | Q9HCP6 | |
| IFFFHFAGGADIFFL | 101 | Q8NGJ1 | |
| MFFFHLLGGADVFSL | 101 | Q8NGE8 | |
| DIFSHIFGGGLFGFM | 86 | O60884 | |
| DVGVFTFDHGMGYFE | 456 | Q86XK2 | |
| FSHFFGDFGFMFGGT | 106 | Q9UBS4 | |
| SLFAQMGFDGFFFGR | 206 | O00754 | |
| HFSFGVGAFPFGFFT | 121 | Q99942 | |
| FFGMHGFLDEIFFTF | 246 | B2RXF0 | |
| DKGFFFAFGAGHFMG | 321 | Q86V40 | |
| GFSFFMVASFGVGAA | 71 | O00322 | |
| FLFAVMFGDFGHGIL | 401 | Q93050 | |
| FPFLFAVMFGDCGHG | 401 | Q9HBG4 | |
| FPFLFAVMFGDVGHG | 396 | Q13488 | |
| FLFAVMFGDFGHGFV | 406 | Q9Y487 | |
| MFGDFGHGFVMFLFA | 411 | Q9Y487 |