Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell proliferation in forebrain

POU3F2 POU3F3 TACC2

3.32e-0538343GO:0021846
GeneOntologyBiologicalProcessforebrain ventricular zone progenitor cell division

POU3F2 POU3F3

3.94e-056342GO:0021869
MousePhenosyndactyly

MYO10 FMN1 FREM1 VCAN

5.03e-0593314MP:0000564
MousePhenomicrophthalmia

GAPVD1 JADE3 ANKRD52 MYO10 FREM1 VCAN

1.23e-04362316MP:0001297
MousePhenoabnormal eye size

GAPVD1 JADE3 ANKRD52 MYO10 FREM1 VCAN

1.49e-04375316MP:0002697
DomainTF_POU_3

POU3F2 POU3F3

1.81e-054332IPR016362
DomainPOU

POU3F2 POU3F3

3.58e-0416332SM00352
DomainPOU_2

POU3F2 POU3F3

3.58e-0416332PS00465
DomainPou

POU3F2 POU3F3

3.58e-0416332PF00157
DomainPOU_dom

POU3F2 POU3F3

3.58e-0416332IPR000327
DomainPOU_3

POU3F2 POU3F3

3.58e-0416332PS51179
DomainPOU_1

POU3F2 POU3F3

3.58e-0416332PS00035
DomainPOU

POU3F2 POU3F3

4.05e-0417332IPR013847
Domain-

POU3F2 POU3F3

1.03e-03273321.10.260.40
DomainLambda_DNA-bd_dom

POU3F2 POU3F3

1.19e-0329332IPR010982
DomainIQ

SCN10A MYO10

6.97e-0371332PF00612
Pubmed

Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals.

POU3F2 POU3F3

2.95e-0633528703082
Pubmed

The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon.

POU3F2 POU3F3

2.95e-06335216547000
Pubmed

Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4.

POU3F2 POU3F3

5.90e-06435226951672
Pubmed

Structure and evolution of four POU domain genes expressed in mouse brain.

POU3F2 POU3F3

5.90e-0643521565620
Pubmed

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

POU3F2 POU3F3

5.90e-06435226265007
Pubmed

The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

POU3F2 POU3F3

9.82e-0653529105675
Pubmed

Cooperative function of POU proteins and SOX proteins in glial cells.

POU3F2 POU3F3

9.82e-0653529632656
Pubmed

Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo.

POU3F2 POU3F3

1.47e-05635215465489
Pubmed

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

POU3F2 POU3F3

1.47e-0563522739723
Pubmed

Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

POU3F2 POU3F3

1.47e-05635215262984
Pubmed

Hippocampus-like corticoneurogenesis induced by two isoforms of the BTB-zinc finger gene Zbtb20 in mice.

POU3F2 POU3F3

2.06e-05735217301088
Pubmed

POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex.

POU3F2 POU3F3

2.74e-05835222892427
Pubmed

Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development.

POU3F2 POU3F3

2.74e-05835219147497
Pubmed

Chromosomal organization of mammalian POU domain factors.

POU3F2 POU3F3

3.53e-0593528276396
Pubmed

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.

POU3F2 POU3F3

3.53e-05935215872005
Pubmed

Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development.

CHL1 POU3F2

4.40e-051035229127326
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

XRN1 RCOR3 GAPVD1 ANKRD52 PALB2

5.91e-0541835534709266
Pubmed

Murine chromosomal location of four class III POU transcription factors.

POU3F2 POU3F3

6.45e-05123528276397
Pubmed

Expression of Pou3f3/Brn-1 and its genomic methylation in developing auditory epithelium.

POU3F2 POU3F3

6.45e-051235219743445
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

XRN1 GAPVD1 JADE3 ANKRD52 MYO10 GYS1 IWS1

6.69e-05103835726673895
Pubmed

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

POU3F2 POU3F3

7.62e-05133528543156
Pubmed

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.

POU3F2 POU3F3

7.62e-051335219403657
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

CHL1 POU3F2 POU3F3

7.83e-058235331073041
Pubmed

Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

POU3F2 POU3F3

8.89e-051435217141158
Pubmed

Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.

POU3F2 POU3F3

1.02e-041535218255031
Pubmed

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.

PATJ PDZD2

1.02e-041535223782696
Pubmed

The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.

POU3F2 POU3F3

1.17e-04163529118797
Pubmed

Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.

POU3F2 POU3F3

1.17e-041635219527706
Pubmed

The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.

POU3F3 PATJ

1.17e-041635214758363
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

CHL1 POU3F2 TACC2 PATJ MYO10 PDZD2

1.47e-0481435623251661
Pubmed

Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

POU3F2 POU3F3

1.85e-042035212130536
Pubmed

Transcriptional regulation of cortical neuron migration by POU domain factors.

POU3F2 POU3F3

1.85e-042035211859196
Pubmed

Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion.

POU3F2 POU3F3

2.91e-042535239271675
Pubmed

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.

POU3F2 POU3F3

3.15e-042635222992956
Pubmed

Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.

ADRB2 GYS1

3.40e-042735220384434
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

RCOR3 ANKRD52 VIRMA YME1L1 GYS1

4.21e-0463835531182584
Pubmed

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.

BNC2 VCAN

5.73e-043535232913205
Pubmed

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.

POU3F2 POU3F3

5.73e-043535222991445
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

PATJ PDZD2

5.73e-043535233864728
Pubmed

Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.

STX16 VCAN

6.07e-043635222421546
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL6A5 FREM1 VCAN

6.36e-0416735322159717
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RCOR3 GAPVD1 TACC2 PATJ FMN1 VCAN

6.77e-04108435611544199
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VIRMA MYO10 SRGAP3 PDZD2

7.26e-0440735412693553
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

ATP6V0A1 YME1L1 GYS1 IWS1

8.31e-0442235427342126
Pubmed

Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.

FGFR4 ADRB2

8.66e-044335220565774
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

GAPVD1 JADE3 VIRMA PALB2 IWS1

1.01e-0377435515302935
CytobandEnsembl 112 genes in cytogenetic band chr9p22

BNC2 FREM1

7.59e-0453352chr9p22
GeneFamilyPOU class homeoboxes and pseudogenes

POU3F2 POU3F3

4.94e-0423262523
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

FREM1 VCAN

1.58e-03412621298
CoexpressionGSE32901_NAIVE_VS_TH1_CD4_TCELL_UP

BNC2 ADRB2 GVINP1 FREM1

2.77e-05131354M8933
CoexpressionGSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP

ADRB2 GVINP1 SRGAP3 DMXL1

4.95e-05152354M2964
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP

CHL1 ADRB2 MYO10 PDZD2

5.08e-05153354M8249
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 FGFR4 MYO10 SRGAP3 FREM1 VCAN

9.53e-0919735631a1852911bda38543916585fda34255fd62a134
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 BNC2 COL6A5 MYO10 FREM1 VCAN

1.01e-08199356a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

BNC2 COL6A5 FGFR4 MYO10 FREM1

3.45e-07187355e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 FGFR4 MYO10 SRGAP3 FREM1

3.64e-07189355203c80030df08ae112f9ae4043709f455d87ce89
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 MYO10 FREM1

3.64e-071893552a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1 VCAN

3.83e-07191355b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 FGFR4 MYO10 FREM1 VCAN

4.14e-07194355011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FGFR4 MYO10 SRGAP3 FREM1 VCAN

4.14e-07194355b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 FGFR4 SRGAP3 FREM1 VCAN

4.35e-071963551450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FGFR4 MYO10 SRGAP3 FREM1 VCAN

4.46e-071973550034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BNC2 FGFR4 SRGAP3 FREM1 VCAN

4.58e-0719835517dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 MYO10 FREM1 VCAN

4.69e-0719935530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 MYO10 FREM1 VCAN

4.81e-07200355a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

ATP6V0A1 ADRB2 SRGAP3 C2CD2

7.22e-0615935497c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

ATP6V0A1 ADRB2 SRGAP3 C2CD2

7.22e-06159354fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 COL6A5 MYO10 FREM1

1.20e-051813549ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PATJ SRGAP3 PDZD2

1.23e-05182354eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 BNC2 PATJ PDZD2

1.37e-05187354c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 BNC2 PATJ SRGAP3

1.37e-05187354c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TACC2 PATJ FMN1 PDZD2

1.37e-051873545df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO10 SRGAP3 FREM1 VCAN

1.37e-05187354a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 BNC2 PATJ PDZD2

1.40e-05188354af740fa78542438fdff627ea1f74f4eee43316be
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.43e-05189354a153b83314cf52808f685296cff8c95af3f4983d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.46e-051903546c7e1086c0a274cd5527c3104106e372811c9905
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 BNC2 PATJ SRGAP3

1.46e-051903541cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 BNC2 PATJ SRGAP3

1.46e-0519035459bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.46e-05190354841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 VCAN

1.46e-0519035445df8fee00f8949937863159d7aa042e72748d9b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.46e-05190354d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TACC2 PATJ SRGAP3 FREM1

1.49e-051913543e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHL1 POU3F3 ADRB2 PDZD2

1.49e-05191354f9a46956778a8773d6656340ecf5d218376d79c2
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.52e-05192354dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.52e-051923546f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell11.5-Distal|11.5 / Age, Tissue, Lineage and Cell class

FGFR4 MYO10 FREM1 VCAN

1.52e-05192354169b9ee2377beb9e4ad35bc82bb7a3dafe8f05b6
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.52e-051923543d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.52e-051923544e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.52e-05192354deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.55e-05193354fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

BNC2 FGFR4 MYO10 FREM1

1.55e-05193354acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 FGFR4 MYO10 FREM1

1.55e-0519335499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

BNC2 COL6A5 FGFR4 FREM1

1.55e-05193354ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.58e-0519435460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.58e-051943546e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 BNC2 COL6A5 FREM1

1.58e-0519435489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

BNC2 COL6A5 FGFR4 FREM1

1.61e-0519535461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO10 SRGAP3 FREM1 VCAN

1.61e-051953540e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.65e-05196354671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.65e-05196354f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 MYO10 FREM1

1.68e-05197354fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 COL6A5 FREM1 VCAN

1.68e-0519735444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 SRGAP3 FREM1 VCAN

1.68e-0519735473a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 FGFR4 VCAN PDZD2

1.71e-0519835402d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.75e-0519935419a97e27a4758e794ce7246d295e112b47931a48
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.75e-05199354e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.75e-05199354333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.75e-05199354e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.75e-05199354c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 MYO10 VCAN

1.75e-051993541a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 MYO10 VCAN

1.75e-05199354211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-052003549b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN PDZD2

1.78e-05200354ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-0520035444a68bacdb3d5bf563bd35952176995850933a81
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 FGFR4 FREM1 VCAN

1.78e-052003543dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-0520035464ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 GAPVD1 TACC2 SRGAP3

1.78e-0520035464462a18afca3c1a8548a857924b8166058bf958
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 FGFR4 MYO10 FREM1

1.78e-05200354e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 FGFR4 FREM1 VCAN

1.78e-05200354311fab076f2ceb258e3970eb21e39344b894042a
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-05200354a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-05200354dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CHL1 COL6A5 FREM1 VCAN

1.78e-05200354bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 COL6A5 FREM1 VCAN

1.78e-0520035458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL6A5 GVINP1 FREM1

2.18e-05693530862e6c8d8af4310b9a1f0879e51ee25115b26b1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL6A5 GVINP1 FREM1

2.18e-0569353d2ff9cea216122d697822cdd2eecbce8f557728d
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MYO10 VCAN PDZD2

1.19e-04122353a2f343962069253a08faa80fd70723b8488a99ec
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATP6V0A1 VCAN DMXL1

1.91e-041433537adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ATP6V0A1 PATJ FMN1

2.20e-041503536a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PATJ SRGAP3 PALB2

2.24e-041513532dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PATJ SRGAP3 PALB2

2.24e-0415135322afd8201eff8471da3456be065f2790de5e4bfe
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 TACC2 VCAN

2.42e-0415535377fdae85d36efb776db977eb424b32487ef222e4
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 MYO10

2.66e-041603530293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 MYO10

2.66e-041603533eaae86fa08f7651021316f8e5811bf48055591e
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FGFR4 FREM1 VCAN

2.71e-04161353b19f82dd98a3064581793711bb70373f18abecd9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 SRGAP3 FREM1

2.71e-04161353176a4a72bb4892932da3c834d1fea5e211847f92
ToppCellCD8+_Memory_T_cell-FLU-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ATP6V0A1 SRGAP3 C2CD2

2.76e-0416235376f39935763848ea6e7917b2f9f1432c543063d9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 VCAN PDZD2

2.86e-041643531cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 VCAN PDZD2

2.86e-04164353a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MYO10 VCAN PDZD2

2.96e-04166353f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FGFR4 FREM1 VCAN

2.96e-0416635365dafed953b01a9830b54309af75c7a561e88336
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 PATJ PDZD2

3.01e-041673533edb0570e583bb527165bcd8a4c25a042054043b
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 FREM1

3.07e-041683531bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 FREM1

3.07e-0416835369f534de0f9a293047bea03cb1b78551087a8df5
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 ADRB2

3.07e-04168353c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCellControl|World / group, cell type (main and fine annotations)

TACC2 PATJ PDZD2

3.07e-04168353a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 FGFR4 ADRB2

3.07e-0416835383b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

TACC2 PATJ PDZD2

3.17e-04170353e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

CHL1 ADRB2 FREM1

3.40e-041743530f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3|TCGA-Breast / Sample_Type by Project: Shred V9

CHL1 ADRB2 FREM1

3.40e-041743537f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCellTCGA-Breast-Solid_Tissue_Normal|TCGA-Breast / Sample_Type by Project: Shred V9

CHL1 ADRB2 FREM1

3.40e-04174353e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

CHL1 ADRB2 FREM1

3.40e-041743531aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 BNC2 COL6A5

3.40e-04174353f90ca117b729436cf452e2ddcec26ba525c5c13b
Diseasecortical thickness

BNC2 POU3F3 TACC2 SRGAP3 VCAN PDZD2

1.54e-031113346EFO_0004840
Diseasebody fat distribution

BNC2 FGFR4 VCAN

1.62e-03202343EFO_0004341
Diseasesevere acute respiratory syndrome, COVID-19

SUN3 PATJ SRGAP3 PDZD2

1.68e-03447344EFO_0000694, MONDO_0100096
Diseasefacial pigmentation measurement

BNC2 FMN1

1.98e-0357342EFO_0006942
Diseasedilated cardiomyopathy (implicated_via_orthology)

ADRB2 YME1L1

3.85e-0380342DOID:12930 (implicated_via_orthology)
Diseaseleptin measurement

PATJ PDZD2

3.94e-0381342EFO_0005000
Diseasecleft lip

FGFR4 GVINP1 FMN1

4.23e-03284343EFO_0003959
DiseaseProstatic Neoplasms

FGFR4 ADRB2 PATJ PALB2

5.31e-03616344C0033578
DiseaseMalignant neoplasm of prostate

FGFR4 ADRB2 PATJ PALB2

5.31e-03616344C0376358

Protein segments in the cluster

PeptideGeneStartEntry
GSHAPDHDVTQERDE

ADRB2

16

P07550
VPSEPHDSNDESNDD

VCAN

2601

P13611
SERPDENHSEPSHQD

BNC2

756

Q6ZN30
DDRNTEHQVHPNASD

GVINP1

921

Q7Z2Y8
DDEDPKSHRDPSNRH

FGFR4

126

P22455
EPHTPSSHDAEEDEP

ANKRD52

506

Q8NB46
SHHNALRTPDVDNPE

DMXL1

656

Q9Y485
HNQGDSDDDVEETHP

RCOR3

151

Q9P2K3
HPDHSLTEQDDRTPG

FMN1

681

Q68DA7
ESEEPPRHQASDSEN

IWS1

186

Q96ST2
SEEPPRHQASDSENE

IWS1

226

Q96ST2
ESEDPPRHQASDSEN

IWS1

251

Q96ST2
SEESQGQPEENHHSE

LUZP4

146

Q9P127
EVGRSQPSQPSDHHE

CHL1

691

O00533
HSTRNGLPDHTDPED

GAPVD1

1141

Q14C86
HVADHEDPDRNTTAA

PDZD2

1936

O15018
SETSTDEHQHVPEDP

CWF19L2

436

Q2TBE0
QPPNSSHSERRHDEV

FREM1

371

Q5H8C1
DSPNPSEHGHSDQRT

MYO10

1006

Q9HD67
HPQARDSSGADQHPD

INSM2

366

Q96T92
TDDTQEHFPHRVSDP

PALB2

121

Q86YC2
STHQEDAPSHPERAA

C2CD2

541

Q9Y426
THRPSDDEVHDAALN

COL6A5

346

A8TX70
HSSPHQSEDEEDPRN

GYS1

651

P13807
NSHDPHSDEDTPTSD

POU3F3

306

P20264
EDHRNSSTETDQQPH

JADE3

551

Q92613
HDPHSDEDTPTSDDL

POU3F2

256

P20265
HDNGTEPHTSDEEVE

SRGAP3

731

O43295
GSPTAEHHPEDTEEQ

PATJ

1781

Q8NI35
QPSNPDSRHGEDEHQ

SCN10A

556

Q9Y5Y9
HLNRPTLDDSSEEEH

STX16

106

O14662
NTHGDPVEDPDHTEE

SUN3

151

Q8TAQ9
NEVQSSHHGEPPSEE

XRN1

1331

Q8IZH2
DAESRDHPSSHSAQP

TACC2

621

O95359
NQHRDVVPEHEAPSS

YME1L1

41

Q96TA2
QHDQLSTHSEDADEP

ATP6V0A1

691

Q93050
PNHSEPDHDTDAGLE

VIRMA

581

Q69YN4