Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	damaged DNA binding	RBBP8 XPC DDB1 CREBBP BRCA1	7.40e-05	84	103	5	GO:0003684
GeneOntologyMolecularFunction	procollagen-proline 3-dioxygenase activity	P3H3 P3H1	7.88e-05	3	103	2	GO:0019797
GeneOntologyMolecularFunction	transcription coregulator activity	ASXL1 RBBP8 CMTM2 XPC AIP RAD54L2 USP16 CREBBP BCLAF3 BRCA1 DNMT3B	1.53e-04	562	103	11	GO:0003712
GeneOntologyMolecularFunction	peptidyl-proline 3-dioxygenase activity	P3H3 P3H1	1.57e-04	4	103	2	GO:0031544
GeneOntologyMolecularFunction	histone modifying activity	USP16 CREBBP BAP1 MST1 RSBN1 KMT5B BAZ1A	1.86e-04	229	103	7	GO:0140993
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	ASXL1 RBBP8 CMTM2 XPC AIP RAD54L2 USP16 DDB1 CREBBP BCLAF3 SPTBN4 BRCA1 HSH2D DNAJB2 DNMT3B SOS1	2.86e-04	1160	103	16	GO:0030674
GeneOntologyMolecularFunction	histone H2A deubiquitinase activity	USP16 BAP1	3.90e-04	6	103	2	GO:0140950
GeneOntologyMolecularFunction	procollagen-proline dioxygenase activity	P3H3 P3H1	7.23e-04	8	103	2	GO:0019798
GeneOntologyMolecularFunction	histone deubiquitinase activity	USP16 BAP1	7.23e-04	8	103	2	GO:0140934
GeneOntologyBiologicalProcess	chromatin organization	ASXL1 ARID4B EP400 H1-7 HJURP RAD54L2 USP16 DDB1 CREBBP BAP1 RSBN1 BRCA1 KMT5B BAZ1A SCMH1 DNMT3B	9.12e-06	896	103	16	GO:0006325
GeneOntologyBiologicalProcess	chromatin remodeling	ARID4B EP400 HJURP RAD54L2 USP16 DDB1 CREBBP BAP1 RSBN1 BRCA1 KMT5B BAZ1A SCMH1 DNMT3B	1.88e-05	741	103	14	GO:0006338
GeneOntologyBiologicalProcess	protein-DNA complex organization	ASXL1 ARID4B EP400 H1-7 HJURP RAD54L2 USP16 DDB1 CREBBP BAP1 RSBN1 BRCA1 KMT5B BAZ1A SCMH1 DNMT3B	3.46e-05	999	103	16	GO:0071824
GeneOntologyBiologicalProcess	regulation of type I interferon production	DHX36 DDX56 DHX33 CREBBP IKBKE TBK1	7.61e-05	141	103	6	GO:0032479
GeneOntologyBiologicalProcess	type I interferon production	DHX36 DDX56 DHX33 CREBBP IKBKE TBK1	8.89e-05	145	103	6	GO:0032606
GeneOntologyCellularComponent	PR-DUB complex	ASXL1 BAP1	1.43e-04	4	103	2	GO:0035517
GeneOntologyCellularComponent	lamellipodium membrane	PIEZO1 EPHA2 VASP	1.67e-04	22	103	3	GO:0031258
GeneOntologyCellularComponent	BRCA1-C complex	RBBP8 BRCA1	3.56e-04	6	103	2	GO:0070533
Domain	RIBOSOMAL_S26E	RPS26 RPS26P11	2.84e-05	2	100	2	PS00733
Domain	Ribosomal_S26e	RPS26 RPS26P11	2.84e-05	2	100	2	PF01283
Domain	Ribosomal_S26e	RPS26 RPS26P11	2.84e-05	2	100	2	IPR000892
Domain	Helicase_C	DHX36 EP400 DDX56 DHX33 RAD54L2	2.75e-04	107	100	5	PF00271
Domain	HELICc	DHX36 EP400 DDX56 DHX33 RAD54L2	2.75e-04	107	100	5	SM00490
Domain	Helicase_C	DHX36 EP400 DDX56 DHX33 RAD54L2	2.87e-04	108	100	5	IPR001650
Domain	HELICASE_CTER	DHX36 EP400 DDX56 DHX33 RAD54L2	2.99e-04	109	100	5	PS51194
Domain	HELICASE_ATP_BIND_1	DHX36 EP400 DDX56 DHX33 RAD54L2	2.99e-04	109	100	5	PS51192
Domain	DEXDc	DHX36 EP400 DDX56 DHX33 RAD54L2	2.99e-04	109	100	5	SM00487
Domain	Helicase_ATP-bd	DHX36 EP400 DDX56 DHX33 RAD54L2	3.12e-04	110	100	5	IPR014001
Domain	DNA/RNA_helicase_DEAH_CS	DHX36 EP400 DHX33	8.61e-04	35	100	3	IPR002464
Domain	DEAH_ATP_HELICASE	DHX36 EP400 DHX33	1.10e-03	38	100	3	PS00690
Domain	2OG-FeII_Oxy_3	P3H3 P3H1	1.51e-03	11	100	2	PF13640
Domain	P4Hc	P3H3 P3H1	3.24e-03	16	100	2	SM00702
Domain	Pro_4_hyd_alph	P3H3 P3H1	3.24e-03	16	100	2	IPR006620
Domain	DUF1605	DHX36 DHX33	3.66e-03	17	100	2	IPR011709
Domain	OB_NTP_bind	DHX36 DHX33	3.66e-03	17	100	2	PF07717
Domain	ZF_ZZ_2	CREBBP HERC2	4.11e-03	18	100	2	PS50135
Domain	ZF_ZZ_1	CREBBP HERC2	4.11e-03	18	100	2	PS01357
Domain	ZZ	CREBBP HERC2	4.11e-03	18	100	2	PF00569
Domain	HA2	DHX36 DHX33	4.11e-03	18	100	2	SM00847
Domain	HA2	DHX36 DHX33	4.11e-03	18	100	2	PF04408
Domain	Helicase-assoc_dom	DHX36 DHX33	4.11e-03	18	100	2	IPR007502
Domain	Znf_ZZ	CREBBP HERC2	4.57e-03	19	100	2	IPR000433
Domain	ZnF_ZZ	CREBBP HERC2	4.57e-03	19	100	2	SM00291
Domain	2OG-FeII_Oxy	P3H3 P3H1	4.57e-03	19	100	2	PF03171
Domain	DH_1	NET1 PLEKHG4B SOS1	4.69e-03	63	100	3	PS00741
Domain	RasGEFN	KNDC1 SOS1	5.06e-03	20	100	2	SM00229
Domain	RasGEF_N	KNDC1 SOS1	5.58e-03	21	100	2	PF00618
Domain	FE2OG_OXY	P3H3 P3H1	5.58e-03	21	100	2	PS51471
Domain	RhoGEF	NET1 PLEKHG4B SOS1	5.80e-03	68	100	3	SM00325
Domain	Ras-like_Gua-exchang_fac_N	KNDC1 SOS1	6.11e-03	22	100	2	IPR000651
Domain	RASGEF_NTER	KNDC1 SOS1	6.11e-03	22	100	2	PS50212
Domain	RhoGEF	NET1 PLEKHG4B SOS1	6.29e-03	70	100	3	PF00621
Domain	DH_2	NET1 PLEKHG4B SOS1	6.29e-03	70	100	3	PS50010
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP IKBKE TBK1	1.14e-05	9	74	3	M47451
Pathway	REACTOME_SUMOYLATION	XPC CREBBP BRCA1 IKBKE SCMH1 HERC2 DNMT3B	5.87e-05	189	74	7	M27214
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP IKBKE TBK1	6.04e-05	15	74	3	M953
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SRRM1 ARID4B EP400 NET1 P3H3 RNF213 DDX56 XPC DDB1 CREBBP RSBN1 FAT1 BRCA1 KMT5B TBK1 AGBL1 SOS1	6.35e-08	1116	108	17	31753913
Pubmed	Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation.	CREBBP IKBKE TBK1	2.90e-07	5	108	3	17015689
Pubmed	Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity.	CREBBP IKBKE TBK1	5.78e-07	6	108	3	34239064
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DHX36 ARID4B HJURP ABCF2 DDX56 RPS26 DHX33 LARP4 DDB1 RSBN1 SLX9 BAZ1A HERC2	7.06e-07	759	108	13	35915203
Pubmed	Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes.	IKBKE TBK1 UBASH3B	2.41e-06	9	108	3	17599067
Pubmed	De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.	RBBP8 ABCF2 DDB1	4.72e-06	11	108	3	37081042
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ARID4B EP400 XPC DDB1 BRCA1 DNMT3B	7.76e-06	150	108	6	28242625
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	EP400 HJURP RAD54L2 PLEKHG4B HSH2D VASP IQCE DNMT3B SOS1	8.25e-06	430	108	9	35044719
Pubmed	Human transcription factor protein interaction networks.	DHX36 ASXL1 ARID4B EP400 DDX56 RAD54L2 LARP4 DDB1 CREBBP BAP1 PCF11 RSBN1 FAT1 BRCA1 HERC2 NUDC	8.75e-06	1429	108	16	35140242
Pubmed	The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression.	RBBP8 BRCA1	9.55e-06	2	108	2	23712259
Pubmed	circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia.	ASXL1 BAP1	9.55e-06	2	108	2	31780633
Pubmed	Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1.	ASXL1 BAP1	9.55e-06	2	108	2	36865140
Pubmed	Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.	IKBKE TBK1	9.55e-06	2	108	2	30082428
Pubmed	Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon.	IKBKE TBK1	9.55e-06	2	108	2	16888014
Pubmed	BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.	RBBP8 BRCA1	9.55e-06	2	108	2	23994874
Pubmed	Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo.	ASXL1 BAP1	9.55e-06	2	108	2	29743720
Pubmed	Cutting edge: Role of TANK-binding kinase 1 and inducible IkappaB kinase in IFN responses against viruses in innate immune cells.	IKBKE TBK1	9.55e-06	2	108	2	17056502
Pubmed	The downregulation of BAP1 expression by BCR-ABL reduces the stability of BRCA1 in chronic myeloid leukemia.	BAP1 BRCA1	9.55e-06	2	108	2	26118501
Pubmed	Characterization of a carboxy-terminal BRCA1 interacting protein.	RBBP8 BRCA1	9.55e-06	2	108	2	9811458
Pubmed	BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms.	BAP1 BRCA1	9.55e-06	2	108	2	36550359
Pubmed	Functionally distinct effects of the C-terminal regions of IKKε and TBK1 on type I IFN production.	IKBKE TBK1	9.55e-06	2	108	2	24722368
Pubmed	Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis.	CREBBP BRCA1	9.55e-06	2	108	2	31499338
Pubmed	Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.	RBBP8 BRCA1	9.55e-06	2	108	2	16101277
Pubmed	The non-canonical IκB kinases IKKε and TBK1 as potential targets for the development of novel therapeutic drugs.	IKBKE TBK1	9.55e-06	2	108	2	23157677
Pubmed	Reducing hyperactivated BAP1 attenuates mutant ASXL1-driven myeloid malignancies in human haematopoietic cells.	ASXL1 BAP1	9.55e-06	2	108	2	34186160
Pubmed	Roles of BRCA1 and its interacting proteins.	RBBP8 BRCA1	9.55e-06	2	108	2	10918303
Pubmed	Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes.	IKBKE TBK1	9.55e-06	2	108	2	27123832
Pubmed	IKKε and TBK1 expression in gastric cancer.	IKBKE TBK1	9.55e-06	2	108	2	27145266
Pubmed	Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells.	IKBKE TBK1	9.55e-06	2	108	2	30349097
Pubmed	BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.	RBBP8 BRCA1	9.55e-06	2	108	2	25582120
Pubmed	Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.	IKBKE TBK1	9.55e-06	2	108	2	15367631
Pubmed	Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.	ASXL1 BAP1	9.55e-06	2	108	2	30013160
Pubmed	IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling.	IKBKE TBK1	9.55e-06	2	108	2	32858764
Pubmed	Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.	IKBKE TBK1	9.55e-06	2	108	2	36936901
Pubmed	Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions.	IKBKE TBK1	9.55e-06	2	108	2	23096996
Pubmed	The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection.	IKBKE TBK1	9.55e-06	2	108	2	15210742
Pubmed	Deubiquitinase BAP1 regulates stability of BRCA1 protein and inactivates the NF-κB signaling to protect mice from sepsis-induced acute kidney injury.	BAP1 BRCA1	9.55e-06	2	108	2	37414201
Pubmed	Breast cancer risk and the BRCA1 interacting protein CTIP.	RBBP8 BRCA1	9.55e-06	2	108	2	18095152
Pubmed	Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia.	ASXL1 BAP1	9.55e-06	2	108	2	35122023
Pubmed	BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.	BAP1 BRCA1	9.55e-06	2	108	2	9528852
Pubmed	Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.	IKBKE TBK1	9.55e-06	2	108	2	22619329
Pubmed	BRCA1 accelerates CtIP-mediated DNA-end resection.	RBBP8 BRCA1	9.55e-06	2	108	2	25310973
Pubmed	The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy.	IKBKE TBK1	9.55e-06	2	108	2	30504235
Pubmed	Rare germline heterozygous missense variants in BRCA1-associated protein 1, BAP1, cause a syndromic neurodevelopmental disorder.	BAP1 BRCA1	9.55e-06	2	108	2	35051358
Pubmed	DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains.	RBBP8 BRCA1	9.55e-06	2	108	2	15485915
Pubmed	DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination.	RBBP8 BRCA1	9.55e-06	2	108	2	28132842
Pubmed	Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?	IKBKE TBK1	9.55e-06	2	108	2	18353649
Pubmed	Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.	ASXL1 BAP1	9.55e-06	2	108	2	37556531
Pubmed	Crystal structure and mechanism of activation of TANK-binding kinase 1.	IKBKE TBK1	9.55e-06	2	108	2	23453971
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SRRM1 RPS26 F5 PCF11 SPTBN4 FAT1 BAZ1A DNAH6	1.78e-05	361	108	8	26167880
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SRRM1 ARID4B XPC DDB1 BAP1 SLX9 BRCA1 BAZ1A SCMH1 HERC2	2.07e-05	608	108	10	36089195
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SRRM1 EP400 DDX56 XPC AIP LARP4 DDB1 GFPT1 PCF11 RSBN1 SLX9 BAZ1A EPHA2 TBK1 HERC2	2.25e-05	1371	108	15	36244648
Pubmed	Characterization of cancer-linked BRCA1-BRCT missense variants and their interaction with phosphoprotein targets.	RBBP8 BRCA1	2.86e-05	3	108	2	19452558
Pubmed	Piezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway.	PIEZO1 CCL25	2.86e-05	3	108	2	39236454
Pubmed	Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA.	XPC DDB1	2.86e-05	3	108	2	22039351
Pubmed	Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study.	IKBKE TBK1	2.86e-05	3	108	2	29755980
Pubmed	EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.	RBBP8 BRCA1	2.86e-05	3	108	2	29513652
Pubmed	RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor.	RBBP8 BRCA1	2.86e-05	3	108	2	35203293
Pubmed	Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.	ASXL1 BAP1	2.86e-05	3	108	2	29345617
Pubmed	Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.	RBBP8 BRCA1	2.86e-05	3	108	2	18285836
Pubmed	BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.	RBBP8 BRCA1	2.86e-05	3	108	2	11739404
Pubmed	ORF45 of Kaposi's sarcoma-associated herpesvirus inhibits phosphorylation of interferon regulatory factor 7 by IKKε and TBK1 as an alternative substrate.	IKBKE TBK1	2.86e-05	3	108	2	22787218
Pubmed	Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response.	RBBP8 BRCA1	2.86e-05	3	108	2	10910365
Pubmed	NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.	RBBP8 BRCA1	2.86e-05	3	108	2	21908405
Pubmed	HTLV-1 Tax protein recruitment into IKKε and TBK1 kinase complexes enhances IFN-I expression.	IKBKE TBK1	2.86e-05	3	108	2	25531185
Pubmed	New role for nuclear hormone receptors and coactivators in regulation of BRCA1-mediated DNA repair in breast cancer cell lines.	CREBBP BRCA1	2.86e-05	3	108	2	16417649
Pubmed	Three Novel Genetic Variants in the FAM110D, CACNA1A, and NLRP12 Genes Are Associated With Susceptibility to Hypertension Among Dai People.	CACNA1A FAM110D	2.86e-05	3	108	2	33621312
Pubmed	Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.	ASXL1 BAP1	2.86e-05	3	108	2	29284740
Pubmed	Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes.	P3H3 P3H1	2.86e-05	3	108	2	15044469
Pubmed	Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype.	BRCA1 HERC2	2.86e-05	3	108	2	27759030
Pubmed	RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci.	RBBP8 BRCA1	2.86e-05	3	108	2	31932421
Pubmed	SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity.	IKBKE TBK1	2.86e-05	3	108	2	25939384
Pubmed	Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.	IKBKE TBK1	2.86e-05	3	108	2	16380379
Pubmed	Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.	ASXL1 BAP1	2.86e-05	3	108	2	33731362
Pubmed	Evasion of antiviral immunity through sequestering of TBK1/IKKε/IRF3 into viral inclusion bodies.	IKBKE TBK1	2.86e-05	3	108	2	24335286
Pubmed	Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.	TBK1 USP35	2.86e-05	3	108	2	32678307
Pubmed	Peroxiredoxin 1 Interacts with TBK1/IKKε and Negatively Regulates Pseudorabies Virus Propagation by Promoting Innate Immunity.	IKBKE TBK1	2.86e-05	3	108	2	34260286
Pubmed	Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.	RBBP8 BRCA1	2.86e-05	3	108	2	10196224
Pubmed	A20 is a negative regulator of IFN regulatory factor 3 signaling.	IKBKE TBK1	2.86e-05	3	108	2	15661910
Pubmed	Specialized distribution of the histone methyltransferase Ezh2 in the nuclear apical region of round spermatids and its interaction with the histone variant H1t2.	H1-7 C4BPA	2.86e-05	3	108	2	22323620
Pubmed	Effect of DNA damage on a BRCA1 complex.	RBBP8 BRCA1	2.86e-05	3	108	2	11689934
Pubmed	BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.	BAP1 BRCA1	2.86e-05	3	108	2	19117993
Pubmed	Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription.	RBBP8 BRCA1	2.86e-05	3	108	2	22832221
Pubmed	The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.	ASXL1 BAP1	2.86e-05	3	108	2	21642991
Pubmed	The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage.	USP16 HERC2	2.86e-05	3	108	2	25305019
Pubmed	Immunohistochemical Evaluation of BAP1 Expression in Breast Cancer with Known BRCA1 and BRCA2 Mutations and Comparison with Histopathological Features.	BAP1 BRCA1	2.86e-05	3	108	2	35261270
Pubmed	Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.	ASXL1 BAP1	2.86e-05	3	108	2	20436459
Pubmed	BAP1/ASXL1 recruitment and activation for H2A deubiquitination.	ASXL1 BAP1	2.86e-05	3	108	2	26739236
Pubmed	Novel serum biomarkers for detection of excessive alcohol use.	ARID4B MST1	2.86e-05	3	108	2	25704570
Pubmed	Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.	EP400 CREBBP	2.86e-05	3	108	2	9590171
Pubmed	Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform.	IKBKE TBK1	2.86e-05	3	108	2	24706939
Pubmed	Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK.	IKBKE TBK1	2.86e-05	3	108	2	17327220
Pubmed	The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter.	CREBBP BRCA1	2.86e-05	3	108	2	9926942
Pubmed	TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.	IKBKE TBK1	2.86e-05	3	108	2	34518217
Pubmed	TUSC4 functions as a tumor suppressor by regulating BRCA1 stability.	BRCA1 HERC2	2.86e-05	3	108	2	25480944
Pubmed	RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance.	RBBP8 BRCA1	2.86e-05	3	108	2	27454289
Pubmed	Phosphorylation of RAB7 by TBK1/IKKε Regulates Innate Immune Signaling in Triple-Negative Breast Cancer.	IKBKE TBK1	2.86e-05	3	108	2	31662325
Pubmed	Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase.	BRCA1 DNMT3B	2.86e-05	3	108	2	31963223
Pubmed	IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2.	IKBKE TBK1	2.86e-05	3	108	2	11839743
Pubmed	UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.	XPC DDB1	2.86e-05	3	108	2	15882621
Interaction	DYRK1B interactions	EP400 RAD54L2 DDB1 CREBBP PLEKHG4B KNDC1	7.63e-06	91	104	6	int:DYRK1B
Interaction	NUP43 interactions	SRRM1 ARID4B EP400 RBBP8 CCDC168 XPC RPS26 RAD54L2 DDB1 RSBN1 BRCA1 BAZ1A NUDC	1.99e-05	625	104	13	int:NUP43
Interaction	ABI1 interactions	CACNA1A SRRM1 HHEX CCDC57 BAP1 EPHA2 VASP SOS1	2.05e-05	223	104	8	int:ABI1
Interaction	RPS19 interactions	DHX36 SRRM1 ASXL1 HJURP DDX56 RPS26 LARP4 BAP1 RSBN1 SLX9 RPS26P11 BRCA1 HERC2	2.51e-05	639	104	13	int:RPS19
Interaction	HDAC2 interactions	ARID4B EP400 RBBP8 ABCF2 DDB1 CREBBP GFPT1 IKZF4 BAP1 BRCA1 BAZ1A C22orf31 TBK1 HERC2 DNMT3B	3.69e-05	865	104	15	int:HDAC2
Interaction	ETS1 interactions	ARID4B EP400 CREBBP BAP1 SPTBN4 BRCA1	3.88e-05	121	104	6	int:ETS1
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	RBBP8 BRCA1	1.34e-04	5	67	2	1336
GeneFamily	DEAH-box helicases	DHX36 DHX33	1.57e-03	16	67	2	500
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP HERC2	1.99e-03	18	67	2	91
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HJURP DHX33 USP16 BRCA1 IKBKE HSH2D UBASH3B	2.04e-07	171	108	7	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	SRRM1 ARID4B ZBTB4 B3GNT7 USP16 RPS26P11 BAZ1A	5.70e-07	199	108	7	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	droplet-Marrow-BM-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 XPC IKBKE BAZ1A ENTPD5 TMEM40	6.40e-06	187	108	6	6be99f71532b7d679d1287ea1bb08245d9538db7
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	DHX36 SRRM1 ARID4B RNF213 USP16 HSH2D	8.62e-06	197	108	6	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	DHX36 SRRM1 ARID4B RNF213 USP16 HSH2D	8.87e-06	198	108	6	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DHX36 SRRM1 ARID4B RNF213 USP16 HSH2D	8.87e-06	198	108	6	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ARID4B ZBTB4 B3GNT7 USP16 BAZ1A EPHA2	9.13e-06	199	108	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	390C-Lymphocytic-ILC\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZNF793 APOBEC3D ZBTB37 GALNT8 SOS1	4.98e-05	164	108	5	b0fc63b72162b5cc4d1e0a271a12f3d3ab29398f
ToppCell	390C-Lymphocytic-ILC-ILC-2\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZNF793 APOBEC3D ZBTB37 GALNT8 SOS1	5.59e-05	168	108	5	2781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr\|Thalamus / BrainAtlas - Mouse McCarroll V32	B3GNT7 USP16 BRCA1 TMEM40	6.00e-05	87	108	4	0c3a3ed1f279ed29a0113cc73ae590157a4b7334
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	B3GNT7 USP16 BRCA1 TMEM40	6.00e-05	87	108	4	5d1dbbd86d82cbce4f2a3365242eb92d9c821a9e
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2\|Thalamus / BrainAtlas - Mouse McCarroll V32	B3GNT7 USP16 BRCA1 TMEM40	6.00e-05	87	108	4	a93dbe73b337cc2d93208822728b9badf30b6870
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)\|Thalamus / BrainAtlas - Mouse McCarroll V32	B3GNT7 USP16 BRCA1 TMEM40	6.00e-05	87	108	4	45ef27ba84f731e4b2188813cd6931950e5164ac
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHEX F5 KIAA0753 TMEM40 DNMT3B	7.35e-05	178	108	5	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KATNAL2 MST1 CCDC154 KNDC1 DNAH6	7.74e-05	180	108	5	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP DCST1 ZBTB37 UBASH3B	8.11e-05	94	108	4	d25f096626af873f724a8cd6454ed56e33fd9854
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP DCST1 ZBTB37 UBASH3B	8.11e-05	94	108	4	2fb80a08f823295fa4c3e6494bf020e5b4052f0f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP IKZF4 ZBTB37 DNAH6 DNMT3B	8.37e-05	183	108	5	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CADM3 ZNF793 P3H1 BSCL2 USP35	8.81e-05	185	108	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CADM3 ZNF793 P3H1 BSCL2 USP35	8.81e-05	185	108	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	CADM3 CCDC57 IKZF4 MST1 IKBKE	9.04e-05	186	108	5	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CADM3 ZNF793 P3H1 BSCL2 USP35	9.04e-05	186	108	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	droplet-Marrow-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 XPC IKBKE ENTPD5 TMEM40	9.04e-05	186	108	5	332931f92352b464c7f23aeebf313cf7db6d499c
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	CADM3 ZNF793 P3H1 BSCL2 USP35	9.04e-05	186	108	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM1 ARID4B CREBBP PCF11 BAZ1A	9.27e-05	187	108	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 RBBP8 XPC IKBKE ENTPD5	9.27e-05	187	108	5	14c239af77116d28d511dea754b6150d20488080
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ASXL1 NET1 CCDC57 RSBN1 BAZ1A	9.50e-05	188	108	5	939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCell	droplet-Marrow-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 XPC IKBKE ENTPD5 TMEM40	9.50e-05	188	108	5	1526e271411e381eae7a342003002276f83f47a3
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RBBP8 HJURP ERI2 BRCA1 DNMT3B	9.50e-05	188	108	5	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MAMLD1 MYOF BAZ1A SCMH1 UBASH3B	1.05e-04	192	108	5	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNA1A CMTM2 F5 AGBL1 VASP	1.13e-04	195	108	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNA1A CMTM2 F5 AGBL1 VASP	1.13e-04	195	108	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	SRRM1 HHEX ARID4B NET1 TBK1	1.16e-04	196	108	5	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KATNAL2 ERI2 ARMC2 PLEKHG4B DNAH6	1.18e-04	197	108	5	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	COVID-19_Severe-PLT_4\|COVID-19_Severe / Disease Group and Platelet Clusters	SRRM1 HHEX ARID4B NET1 TBK1	1.21e-04	198	108	5	abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	SRRM1 ZBTB4 USP16 BAZ1A SOS1	1.21e-04	198	108	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	SRRM1 ARID4B B3GNT7 USP16 BAZ1A	1.24e-04	199	108	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CADM3 HHEX NET1 FAM110D F5	1.24e-04	199	108	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	SRRM1 B3GNT7 USP16 RPS26P11 BAZ1A	1.24e-04	199	108	5	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CADM3 HHEX NET1 FAM110D MAMLD1	1.27e-04	200	108	5	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Sigmoid-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	APOBEC3D HJURP KIAA0753 MYOF BRCA1	1.27e-04	200	108	5	4e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A ERI2 EPHA2 UBASH3B DNAJB2	1.27e-04	200	108	5	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FREM1 FAT1 ADRA1A FRMPD3 UBASH3B	1.27e-04	200	108	5	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Sigmoid-(1)_T_cell-(18)_cycling_gd_T\|Sigmoid / shred on region, Cell_type, and subtype	APOBEC3D HJURP KIAA0753 MYOF BRCA1	1.27e-04	200	108	5	6e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	ZNF793 B3GNT7 UBASH3B CCL25 ZNF614	1.27e-04	200	108	5	c2df917900872453ea17a39928e39d071a6d3339
ToppCell	Sigmoid-T_cell-cycling_gd_T\|Sigmoid / Region, Cell class and subclass	APOBEC3D HJURP KIAA0753 MYOF BRCA1	1.27e-04	200	108	5	9769185abae084ffac36420c749625e679b70ca8
Disease	myelodysplastic syndrome (implicated_via_orthology)	ASXL1 CREBBP BAP1	1.99e-05	15	106	3	DOID:0050908 (implicated_via_orthology)
Disease	xeroderma pigmentosum (implicated_via_orthology)	XPC DDB1	1.90e-04	6	106	2	DOID:0050427 (implicated_via_orthology)
Disease	Disease Exacerbation	ABCF2 XPC RPS26 DDB1 EPHA2	3.31e-04	165	106	5	C0235874
Disease	hepatocyte growth factor-like protein measurement	RAD54L2 TMEM89 MST1	3.47e-04	38	106	3	EFO_0008154
Disease	Neoplasm of uncertain or unknown behavior of breast	BAP1 BRCA1 HERC2	4.35e-04	41	106	3	C0496956
Disease	Breast adenocarcinoma	BAP1 BRCA1 HERC2	4.35e-04	41	106	3	C0858252
Disease	Adenoid Cystic Carcinoma	ARID4B CREBBP FAT1 BRCA1	4.73e-04	100	106	4	C0010606
Disease	Diamond-Blackfan anemia (implicated_via_orthology)	RPS26 RPS26P11	5.65e-04	10	106	2	DOID:1339 (implicated_via_orthology)
Disease	Noonan Syndrome 1	EPHA2 SOS1	6.88e-04	11	106	2	C4551602
Disease	Turner Syndrome, Male	EPHA2 SOS1	6.88e-04	11	106	2	C0041409
Disease	Female Pseudo-Turner Syndrome	EPHA2 SOS1	6.88e-04	11	106	2	C1527404
Disease	Adenocarcinoma of lung (disorder)	TRPM6 XPC CREBBP BAP1 SOS1	9.05e-04	206	106	5	C0152013
Disease	Benign tumor of pancreas	RBBP8 BRCA1	9.72e-04	13	106	2	C0347284
Disease	male infertility (implicated_via_orthology)	ARMC2 BSCL2	9.72e-04	13	106	2	DOID:12336 (implicated_via_orthology)
Disease	antisaccade response measurement	B3GNT7 GALNT8 RNF32-DT	1.09e-03	56	106	3	EFO_0006874
Disease	pro-hydroxy-pro measurement	TRPM6 APLN	1.48e-03	16	106	2	EFO_0021132
Disease	Pancreatic carcinoma	RBBP8 BRCA1	2.10e-03	19	106	2	C0235974
Disease	LEOPARD Syndrome	EPHA2 SOS1	2.82e-03	22	106	2	C0175704
Disease	partial thromboplastin time	F5 AGBL1	3.35e-03	24	106	2	EFO_0004310
Disease	Cancer of Head	BAP1 FAT1	3.35e-03	24	106	2	C0751177
Disease	Head Neoplasms	BAP1 FAT1	3.35e-03	24	106	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	BAP1 FAT1	3.35e-03	24	106	2	C0887900
Disease	Noonan Syndrome	EPHA2 SOS1	3.35e-03	24	106	2	C0028326
Disease	acute myeloid leukemia (is_implicated_in)	ASXL1 CREBBP DNMT3B	3.48e-03	84	106	3	DOID:9119 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HRRRKENQGSGVPVS	CACNA1A	1026	O00555
KRCRHPGELRNGQVE	C4BPA	111	P04003
IGKKTNRGRRSNHIP	ARID4B	136	Q4LE39
RRSKRLVVSNNGPNH	ERI2	601	A8K979
QSKRPRLEVGHQGVV	EP400	516	Q96L91
QRPRKGHEENGDVVT	ABCF2	21	Q9UG63
SQHKRLPSQQREIRG	SLC4A9	341	Q96Q91
HRKVCGNPKSREVQR	CCL25	71	O15444
RGPVLPKRQSNHRQE	APOBEC3D	56	Q96AK3
RKRGVFRNQVDPETH	APOBEC3D	246	Q96AK3
SGVNRLRRKENPHVR	RBBP8	171	Q99708
PRSTRGRQGRNHVDE	DNMT3B	121	Q9UBC3
QVTLRIHRKNAPAGG	ADRA1A	231	P35348
QKPVGQRGEQHRAQR	ARMC2	581	Q8NEN0
RVNKFLRRQNHPEAG	CREBBP	1341	Q92793
RQGVSIGRLHKQRKP	BAP1	701	Q92560
DGNVRHLVQPRGSRN	APLN	36	Q9ULZ1
AQRDRFPGRKQPGVH	C22orf31	261	O95567
TGRPKGVLSTHQNIR	ACSF3	206	Q4G176
RSQHTKANRQREPGL	ACADM	21	P11310
QLARAVKPHQIGGIR	RAD54L2	266	Q9Y4B4
RKGDQELHGEPTRIQ	CADM3	166	Q8N126
HLRGVREKVDGLPQQ	CCDC154	456	A6NI56
QRGPATRQRDGHFKK	ASXL1	396	Q8IXJ9
RGRPPKRIHISQEDN	BAZ1A	276	Q9NRL2
RNIAVGKDPLEGQRH	AIP	106	O00170
RTKNERAHPVDGLQG	AGBL1	1006	Q96MI9
IVSRPTIRQGHGENR	HJURP	416	Q8NCD3
KHGGVQAPRPRVVRA	RNF32-DT	66	Q8NI28
QPRGDRNKDHERLRG	IQCE	381	Q6IPM2
ENPHGVKAVTRGQRC	P3H1	656	Q32P28
SRRHQRVQDKTGRAP	P3H3	716	Q8IVL6
THQTQPGIRRARDKA	NET1	571	Q7Z628
IRQQGTRHGRSPQVG	FAT1	3956	Q14517
VRGKLHQPEEVQRGS	ENTPD5	311	O75356
QRPLHKRKGGQVRFS	HHEX	131	Q03014
HVRRPRQVQGLQGKK	HERC2	4236	O95714
HNNPVRFRPIKGRQE	KMT5B	121	Q4FZB7
LRENGIVHRDIKPGN	IKBKE	126	Q14164
HRKATGPVVEQAVRG	DDX56	71	Q9NY93
HRAGRTARANNPGIV	DDX56	371	Q9NY93
RLGEHNLRKRDGPEQ	KLK15	71	Q9H2R5
RKDSGEENAHPRRGQ	KATNAL2	171	Q8IYT4
VKVPQRKHVRRTVNG	FAM222B	66	Q8WU58
AREPQHGVVRRAGVT	FREM1	931	Q5H8C1
RRKSGRHEAPRGQAK	H1-7	91	Q75WM6
PERGQRVRQQLKSHL	HSH2D	211	Q96JZ2
RKTHQNGDLQIRGGR	GTSCR1	36	Q86UQ5
KGTNRDPRLNRISQH	PCF11	291	O94913
RDKPRQGGRHIQAIR	MOGAT2	61	Q3SYC2
VRGDVVNGRNHQGPK	BRCA1	1736	P38398
VNGRNHQGPKRARES	BRCA1	1741	P38398
RAGREPQGVSQQHVR	FGF8	41	P55075
QHKDAVALRPTRNVG	DNAH6	656	Q9C0G6
EVEGNHRNTRVRPFK	BCLAF3	636	A2AJT9
GQLGQQIRRHPSFKR	BNIP5	551	P0C671
RAPQRHSRGEGVNTI	GFY	371	I3L273
RGQRRKQPHTTVQRL	DCST1	11	Q5T197
KKPAGGREAQHRRQG	DNAJB2	271	P25686
GREAQHRRQGRPKAQ	DNAJB2	276	P25686
PKRRAVQSQEQGRHL	FRMPD3	716	Q5JV73
RHPERKGLAQARNTG	GALNT8	251	Q9NY28
AKQRKGRAGRVQPGH	DHX36	596	Q9H2U1
NDDIKRIGVRLPGHQ	EPHA2	941	P29317
HNPPSRREEVQGVRK	DHX33	536	Q9H6R0
LGKHQPRSAQVGSRL	CCDC57	761	Q2TAC2
SPGRKHQGTVKRRQE	MAMLD1	51	Q13495
HRAIPQGVTRRNGKE	LARP4	701	Q71RC2
NVNKHPGGRQKARIL	KNDC1	1236	Q76NI1
GQKQDRTGRPHVILT	CCDC168	4811	Q8NDH2
DQRRSKLRVVGGHPG	MST1	476	P26927
AQREHGVLGGKLRQR	DDAH2	41	O95865
RKEVQRRISAHQPGP	BSCL2	281	Q96G97
GDVLQHARPIRRKDN	B3GNT7	266	Q8NFL0
ITRAHGNVQDRIGRP	DDB1	101	Q16531
RVRTPGSHRQGKDNL	IKZF4	16	Q9H2S9
PHAGVSPRGVKRQRR	RSBN1	76	Q5VWQ0
FPRVRHKSLQVRQDG	F5	1001	P12259
RIKRTAGDHPGRAVQ	GFPT1	311	Q06210
DIRRGVNQALKHPSR	WDR19	826	Q8NEZ3
GLRKAERGRQSQPHS	KIAA0753	516	Q2KHM9
IIQRKKIARDNGPGH	SOS1	736	Q07889
THQVIARRQEPALRG	FAM110D	31	Q8TAY7
DIQRRHLRVGLKGQP	NUDC	201	Q9Y266
STKTVLEHQPGQRGR	SCMH1	261	Q96GD3
VQPKHEVGTRRGCRR	CMTM2	56	Q8TAZ6
DRTQTGHVLGNPQRR	RNF213	4551	Q63HN8
KLLQRINHGRRPNGE	ZNF793	171	Q6ZN11
GAAHSRKQRQPARLQ	ZBTB45	166	Q96K62
RHNTPKGNRRGQVSA	ZBTB37	166	Q5TC79
QKIHCRSRQGVPVVG	TRPM6	276	Q9BX84
EPVCRHIRKGLEQGN	USP16	21	Q9Y5T5
AKKGRGHVQPIRCTN	RPS26P11	11	Q5JNZ5
RLHPEGSSRKQQRAQ	SOGA3	26	Q5TF21
PGTRDRHGRAVVQVR	PLEKHG4B	206	Q96PX9
HVKNGEVGRRRRHSP	SRRM1	511	Q8IYB3
GRVGPRRQRKHCITE	USP35	636	Q9P2H5
DQQPRATGKHRRSLG	TMEM40	76	Q8WWA1
PKRLQTHEAQCRRGA	ZBTB4	246	Q9P1Z0
KNQGLRREIQAHGPR	SPTBN4	1556	Q9H254
GLRARVHQAAVRPKG	SLX9	6	Q9NSI2
GTPAPEHNEKRQRRQ	TMEM208	151	Q9BTX3
LQGRRRSQATKGEHP	TMEM89	86	A2RUT3
AKKGRGHVQPIRCTN	RPS26	11	P62854
QEKHRQGRVDRSRPQ	PIEZO1	1361	Q92508
RNRQQRPGTIKHGSA	UBASH3B	26	Q8TF42
GDKQEKATQRRPHGR	XPC	406	Q01831
QKRRHGINNPVEFIG	ZNF614	146	Q8N883
LRENGIVHRDIKPGN	TBK1	126	Q9UHD2
QKRQQPGPSEHIERR	VASP	141	P50552
NQDPLGIQGRRIHKE	NAGA	306	P17050
GQTHRTRIKRGNNPF	MYOF	226	Q9NZM1
QKHIGKGSSQERPIR	NEXN-AS1	6	Q8NBZ9