Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvirion binding

CLEC4M CD209 NECTIN1

1.95e-05101113GO:0046790
GeneOntologyMolecularFunctionICAM-3 receptor activity

CLEC4M ITGAL

9.15e-0531112GO:0030369
GeneOntologyMolecularFunctionvirus receptor activity

CLEC4M CD209 TYRO3 NECTIN1 CXADR

1.12e-04851115GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

CLEC4M CD209 TYRO3 NECTIN1 CXADR

1.18e-04861115GO:0140272
GeneOntologyMolecularFunction(1->3)-beta-D-glucan binding

CLEC4M CD209

1.82e-0441112GO:0001872
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PRTG FAT4 DSC3 PCDHGA6 PECAM1 ITGAL CD209 NECTIN1 CXADR CDH15

1.11e-0531311610GO:0098742
GeneOntologyBiologicalProcesspositive regulation of viral life cycle

TRIM21 CLEC4M CD209 TYRO3

1.51e-05271164GO:1903902
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

FAT4 ITGAL CD209 NECTIN1 CXADR

2.80e-05631165GO:0007157
GeneOntologyBiologicalProcesssymbiont entry into host cell

KIAA0319L TRIM21 CLEC4M CD209 TYRO3 NECTIN1 CXADR

4.82e-051691167GO:0046718
GeneOntologyBiologicalProcesssymbiont entry into host

KIAA0319L TRIM21 CLEC4M CD209 TYRO3 NECTIN1 CXADR

6.24e-051761167GO:0044409
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PRTG FAT4 DSC3 PCDHGA6 PECAM1 NECTIN1 CDH15

9.13e-051871167GO:0007156
GeneOntologyBiologicalProcessB cell adhesion

CLEC4M CD209

9.37e-0531162GO:0097323
GeneOntologyBiologicalProcesspeptide antigen transport

CLEC4M CD209

9.37e-0531162GO:0046968
GeneOntologyBiologicalProcessdetection of yeast

CLEC4M CD209

1.87e-0441162GO:0001879
GeneOntologyBiologicalProcessmitotic spindle assembly checkpoint signaling

NDC80 ATM ZW10 GEN1

1.94e-04511164GO:0007094
GeneOntologyBiologicalProcessspindle assembly checkpoint signaling

NDC80 ATM ZW10 GEN1

1.94e-04511164GO:0071173
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

KIF18A GOLGA8N NDC80 ATM ZW10 GOLGA8O GEN1

1.99e-042121167GO:0000070
GeneOntologyBiologicalProcessnegative regulation of mitotic metaphase/anaphase transition

NDC80 ATM ZW10 GEN1

2.25e-04531164GO:0045841
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid segregation

NDC80 ATM ZW10 GEN1

2.25e-04531164GO:0033048
GeneOntologyBiologicalProcessnegative regulation of sister chromatid segregation

NDC80 ATM ZW10 GEN1

2.25e-04531164GO:0033046
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid separation

NDC80 ATM ZW10 GEN1

2.25e-04531164GO:2000816
GeneOntologyBiologicalProcessmitotic spindle checkpoint signaling

NDC80 ATM ZW10 GEN1

2.25e-04531164GO:0071174
GeneOntologyBiologicalProcessnegative regulation of metaphase/anaphase transition of cell cycle

NDC80 ATM ZW10 GEN1

2.60e-04551164GO:1902100
GeneOntologyBiologicalProcessnegative regulation of chromosome separation

NDC80 ATM ZW10 GEN1

2.60e-04551164GO:1905819
GeneOntologyBiologicalProcessspindle checkpoint signaling

NDC80 ATM ZW10 GEN1

2.98e-04571164GO:0031577
GeneOntologyBiologicalProcessnegative regulation of chromosome segregation

NDC80 ATM ZW10 GEN1

2.98e-04571164GO:0051985
GeneOntologyBiologicalProcessbiological process involved in interaction with host

KIAA0319L TRIM21 CLEC4M CD209 TYRO3 NECTIN1 CXADR

3.09e-042281167GO:0051701
GeneOntologyBiologicalProcessdetection of fungus

CLEC4M CD209

3.10e-0451162GO:0016046
GeneOntologyBiologicalProcesstransport of virus

KIAA0319L CLEC4M CD209

3.22e-04241163GO:0046794
GeneOntologyBiologicalProcessmitotic cell cycle checkpoint signaling

BRCA1 NDC80 ATM ZW10 CLSPN GEN1

3.22e-041631166GO:0007093
GeneOntologyBiologicalProcesscentrosome cycle

GOLGA8N BRCA1 NDC80 CEP295 GOLGA8O GEN1

3.33e-041641166GO:0007098
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid segregation

NDC80 ATM ZW10 GEN1

3.63e-04601164GO:0033047
GeneOntologyBiologicalProcessphosphatidylinositol metabolic process

PIGG PLA2G4E SLC27A1 PLCB1 ATM PLCE1

4.03e-041701166GO:0046488
GeneOntologyBiologicalProcessmeiotic nuclear division

KIF18A GOLGA8N NDC80 PLCB1 SGO2 ATM GOLGA8O

4.21e-042401167GO:0140013
GeneOntologyBiologicalProcessregulation of proton transport

ACTN4 PLCB1 NR3C2

4.59e-04271163GO:0010155
GeneOntologyBiologicalProcesspositive regulation of sodium:proton antiporter activity

ACTN4 PLCB1

4.63e-0461162GO:0032417
GeneOntologyBiologicalProcessnegative regulation of mitotic nuclear division

NDC80 ATM ZW10 GEN1

4.65e-04641164GO:0045839
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid separation

NDC80 ATM ZW10 GEN1

4.65e-04641164GO:0010965
GeneOntologyBiologicalProcesscell-cell junction organization

EPHB2 PECAM1 GJC1 ACTN4 NECTIN1 CXADR CDH15

4.88e-042461167GO:0045216
GeneOntologyBiologicalProcessmeiotic spindle assembly

GOLGA8N NDC80 GOLGA8O

5.12e-04281163GO:0090306
GeneOntologyBiologicalProcessmicrotubule organizing center organization

GOLGA8N BRCA1 NDC80 CEP295 GOLGA8O GEN1

5.30e-041791166GO:0031023
GeneOntologyBiologicalProcessmitotic sister chromatid separation

NDC80 ATM ZW10 GEN1

5.54e-04671164GO:0051306
GeneOntologyBiologicalProcesssister chromatid segregation

KIF18A GOLGA8N NDC80 ATM ZW10 GOLGA8O GEN1

5.90e-042541167GO:0000819
GeneOntologyBiologicalProcesspositive regulation of viral process

TRIM21 CLEC4M CD209 TYRO3

6.19e-04691164GO:0048524
GeneOntologyBiologicalProcessregulation of sodium:proton antiporter activity

ACTN4 PLCB1

6.46e-0471162GO:0032415
GeneOntologyBiologicalProcessadiponectin-activated signaling pathway

SLC27A1 APPL1

6.46e-0471162GO:0033211
GeneOntologyBiologicalProcessnatural killer cell activation

TYRO3 TYROBP RASGRP1 RAET1L HECTD1

6.82e-041241165GO:0030101
GeneOntologyCellularComponentGolgi cis cisterna

GOLGA8R GOLGA8Q GOLGA8N GOLGA8O

3.36e-05331174GO:0000137
GeneOntologyCellularComponentcell-cell junction

DSC3 PECAM1 LAMA1 GJC1 ACTN4 ITGAL PPL IQGAP1 NECTIN1 NHS CXADR CDH15

1.20e-0459111712GO:0005911
GeneOntologyCellularComponentGolgi cisterna membrane

GOLGA8R GOLGA8Q B4GALT5 GOLGA8N GOLGA8O

1.86e-04941175GO:0032580
DomainGOLGA2L5

GOLGA8R GOLGA8N GOLGA8O

1.65e-04181133PF15070
DomainGolgin_A

GOLGA8R GOLGA8N GOLGA8O

1.65e-04181133IPR024858
DomainMacrogloblnA2_thiol-ester-bond

A2M CPAMD8

9.92e-0481132IPR019565
DomainThiol-ester_cl

A2M CPAMD8

9.92e-0481132PF10569
DomainMacrogloblnA2_CS

A2M CPAMD8

9.92e-0481132IPR019742
DomainA2M_N_2

A2M CPAMD8

9.92e-0481132SM01359
Domain-

A2M CPAMD8

9.92e-04811322.60.40.690
DomainA2M_recep

A2M CPAMD8

9.92e-0481132SM01361
DomainA2M

A2M CPAMD8

9.92e-0481132SM01360
DomainA2M

A2M CPAMD8

1.58e-03101132PF00207
DomainA2M_N_2

A2M CPAMD8

1.58e-03101132IPR011625
DomainA2M_comp

A2M CPAMD8

1.58e-03101132IPR011626
DomainA2M_recep

A2M CPAMD8

1.58e-03101132PF07677
DomainA2M_comp

A2M CPAMD8

1.58e-03101132PF07678
DomainA2M_N

A2M CPAMD8

1.58e-03101132PF01835
DomainA2M_N

A2M CPAMD8

1.58e-03101132IPR002890
DomainA-macroglobulin_rcpt-bd

A2M CPAMD8

1.58e-03101132IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M CPAMD8

1.58e-03101132PS00477
DomainA2M_N_2

A2M CPAMD8

1.58e-03101132PF07703
DomainMacroglobln_a2

A2M CPAMD8

1.58e-03101132IPR001599
Domain-

A2M CPAMD8

2.30e-031211321.50.10.20
DomainHEAT

PPP4R1 PPP2R1B UTP20

3.06e-03481133PF02985
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH9

3.15e-03141132IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH9

3.15e-03141132IPR024743
DomainTUDOR

TDRD15 TDRD3

3.15e-03141132PF00567
DomainMT

DNAH14 DNAH9

3.15e-03141132PF12777
DomainAAA_8

DNAH14 DNAH9

3.15e-03141132PF12780
DomainDHC_fam

DNAH14 DNAH9

3.62e-03151132IPR026983
DomainEF-hand_like

PLCB1 PLCE1

3.62e-03151132PF09279
DomainPI-PLC-Y

PLCB1 PLCE1

3.62e-03151132PF00387
DomainPLCYc

PLCB1 PLCE1

3.62e-03151132SM00149
DomainDynein_heavy

DNAH14 DNAH9

3.62e-03151132PF03028
DomainPLipase_C_Pinositol-sp_Y

PLCB1 PLCE1

3.62e-03151132IPR001711
DomainPIPLC_Y_DOMAIN

PLCB1 PLCE1

3.62e-03151132PS50008
DomainDynein_heavy_dom

DNAH14 DNAH9

3.62e-03151132IPR004273
DomainPI-PLC_fam

PLCB1 PLCE1

3.62e-03151132IPR001192
DomainPLC_EF-hand-like

PLCB1 PLCE1

3.62e-03151132IPR015359
DomainMethyltransf_11

BUD23 PRMT6

4.12e-03161132IPR013216
DomainMethyltransf_11

BUD23 PRMT6

4.12e-03161132PF08241
Domain-

PLXNA3 IQGAP1

4.12e-031611321.10.506.10
DomainCadherin_CS

FAT4 DSC3 PCDHGA6 CDH15

4.34e-031091134IPR020894
DomainHEAT_type_2

PPP4R1 PPP2R1B

4.65e-03171132IPR021133
DomainVWA

COL6A5 ITGAL COL21A1

4.74e-03561133PF00092
DomainCADHERIN_1

FAT4 DSC3 PCDHGA6 CDH15

4.93e-031131134PS00232
DomainCadherin

FAT4 DSC3 PCDHGA6 CDH15

4.93e-031131134PF00028
DomainCADHERIN_2

FAT4 DSC3 PCDHGA6 CDH15

5.09e-031141134PS50268
Domain-

FAT4 DSC3 PCDHGA6 CDH15

5.09e-0311411342.60.40.60
DomainPI-PLC-X

PLCB1 PLCE1

5.21e-03181132PF00388
DomainTerpenoid_cyclase/PrenylTrfase

A2M CPAMD8

5.21e-03181132IPR008930
DomainPLCXc

PLCB1 PLCE1

5.21e-03181132SM00148
DomainRasGAP_dom

PLXNA3 IQGAP1

5.21e-03181132IPR001936
DomainHEAT

PPP4R1 PPP2R1B UTP20

5.23e-03581133IPR000357
DomainLaminin_G

FAT4 LAMA1 COL21A1

5.23e-03581133IPR001791
DomainCA

FAT4 DSC3 PCDHGA6 CDH15

5.25e-031151134SM00112
DomainCadherin-like

FAT4 DSC3 PCDHGA6 CDH15

5.41e-031161134IPR015919
DomainCadherin

FAT4 DSC3 PCDHGA6 CDH15

5.75e-031181134IPR002126
DomainPIPLC_X_DOMAIN

PLCB1 PLCE1

5.80e-03191132PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB1 PLCE1

5.80e-03191132IPR000909
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

AMPD2 NCKAP1 ETF1 RANBP9 DAPK1 TRIM21 RTN1 MAP3K5 IQGAP1 GOLGA8N TDRD3 EIF4A1 PLCB1 APPL1 RIMS1 GOLGA8O

1.76e-079631181628671696
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PPP4R1 USP11 KIAA0319L RANBP9 ACTN4 BRWD3 IQGAP1 PRKRA ZBTB44 SCG2 EIF4A1 APPL1 ATM HECTD1 PADI2 GEN1 BTRC DOP1B

3.48e-0712851181835914814
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 IARS1 VPS13C LAMA1 DNAH14 KMT2C ZBTB44 TDRD3 UTP20 CEP295 ATM ITPRIPL1 DOP1B

1.39e-067361181329676528
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

AMPD2 NCKAP1 IARS1 RANBP9 MRPS27 ACTN4 LDHA RTN1 PRKRA NECTIN1 PLCB1 APPL1 RIMS1 DAAM1 BTRC CXADR

1.60e-0611391181636417873
Pubmed

A phenotype-based screen for embryonic lethal mutations in the mouse.

PECAM1 POGLUT1 HECTD1

2.11e-06811839636176
Pubmed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

LDHA BRCA1 SLC27A1 ATM GEN1

2.11e-0661118527694478
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NCKAP1 USP11 U2AF2 ACTN4 THOC2 IQGAP1 PRKRA EIF4A1 NLE1 UTP20 ATM HECTD1

2.42e-066531181222586326
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

NCKAP1 POGK MRPS27 U2AF2 GMPR2 SAP30 IQGAP1 PRKRA BUD23 EIF4A1 NLE1 UTP20

5.21e-067041181229955894
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

A2M DSC3 IARS1 ETF1 MRPS27 U2AF2 ACTN4 TRIM21 THOC2 LDHA PPL IQGAP1 PRKRA EIF4A1 NLE1 UTP20

5.62e-0612571181636526897
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PPP4R1 BPIFB3 NCKAP1 USP11 IARS1 SAMD4B RANBP9 U2AF2 IQGAP1 PRKRA KMT2C RASGRP1 EIF4A1 SGO2 RIMS1 ZW10

7.33e-0612841181617353931
Pubmed

Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo.

CLEC4M CD209

1.14e-052118212351402
Pubmed

Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs.

CLEC4M CD209

1.14e-052118225870292
Pubmed

The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection.

CLEC4M CD209

1.14e-052118218981244
Pubmed

Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity.

BRCA1 ATM

1.14e-052118221849032
Pubmed

Molecular characterization of the murine SIGNR1 gene encoding a C-type lectin homologous to human DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118212137941
Pubmed

Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN.

CLEC4M CD209

1.14e-052118211581396
Pubmed

Constitutive activation of the ATM/BRCA1 pathway prevents DNA damage-induced apoptosis in 5-azacytidine-resistant cell lines.

BRCA1 ATM

1.14e-052118224680865
Pubmed

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.

BRCA1 CLSPN

1.14e-052118215096610
Pubmed

Role of homozygous DC-SIGNR 5/5 tandem repeat polymorphism in HIV-1 exposed seronegative North Indian individuals.

CLEC4M CD209

1.14e-052118217876530
Pubmed

C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans.

CLEC4M CD209

1.14e-052118212050398
Pubmed

The clinical significance of DC-SIGN and DC-SIGNR, which are novel markers expressed in human colon cancer.

CLEC4M CD209

1.14e-052118225504222
Pubmed

Utilization of human DC-SIGN and L-SIGN for entry and infection of host cells by the New World arenavirus, Junín virus.

CLEC4M CD209

1.14e-052118224183720
Pubmed

Murine SIGNR1 (CD209b) Contributes to the Clearance of Uropathogenic Escherichia coli During Urinary Tract Infections.

CLEC4M CD209

1.14e-052118231998663
Pubmed

Human lectins and their roles in viral infections.

CLEC4M CD209

1.14e-052118225642836
Pubmed

Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118211739956
Pubmed

L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus.

CLEC4M CD209

1.14e-052118215371595
Pubmed

Autonomous tetramerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118219249311
Pubmed

N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN.

CLEC4M CD209

1.14e-052118221191006
Pubmed

Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis.

CLEC4M CD209

1.14e-052118217224292
Pubmed

Oligomerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR: Sequence variation and stability differences.

CLEC4M CD209

1.14e-052118227859859
Pubmed

Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins.

CLEC4M CD209

1.14e-052118216682406
Pubmed

Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1.

BRCA1 ATM

1.14e-052118219996295
Pubmed

DC-SIGN and DC-SIGNR polymorphic variants in Northern Asian Indians.

CLEC4M CD209

1.14e-052118219046307
Pubmed

Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120.

CLEC4M CD209

1.14e-05211821518869
Pubmed

Comparison of the carbohydrate preference of SIGNR1 as a phagocytic receptor with the preference as an adhesion molecule.

CLEC4M CD209

1.14e-052118224434373
Pubmed

Comparison of collagen propeptides as growth markers in children with inflammatory bowel disease.

BRCA1 ATM

1.14e-05211822001833
Pubmed

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2.

CLEC4M CD209

1.14e-052118212609975
Pubmed

Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins down regulate both DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118223460925
Pubmed

Lewis Lung Cancer Cells Promote SIGNR1(CD209b)-Mediated Macrophages Polarization Induced by IL-4 to Facilitate Immune Evasion.

CLEC4M CD209

1.14e-052118226447454
Pubmed

[Relationship between intrauterine infection and the gene polymorphism of DC-SIGN/DC-SIGNR in the pregnant women of HBV positive].

CLEC4M CD209

1.14e-052118222338216
Pubmed

The polymorphisms in DC-SIGNR affect susceptibility to HIV type 1 infection.

CLEC4M CD209

1.14e-052118217530994
Pubmed

Specific asparagine-linked glycosylation sites are critical for DC-SIGN- and L-SIGN-mediated severe acute respiratory syndrome coronavirus entry.

CLEC4M CD209

1.14e-052118217715238
Pubmed

Determination of DC-SIGN and DC-SIGNR repeat region variations.

CLEC4M CD209

1.14e-052118216061998
Pubmed

Role of DC-SIGN and L-SIGN receptors in HIV-1 vertical transmission.

CLEC4M CD209

1.14e-052118221277928
Pubmed

D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice.

DRD1 PLCB1

1.14e-052118224227722
Pubmed

HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures.

IQGAP1 HECTD1

1.14e-052118228073378
Pubmed

[Genetic polymorphism of dendritic cell-specific ICAM-3 grabbing nonintegrin and DC-SIGNR's exon 4 in Chinese hepatitis C patients].

CLEC4M CD209

1.14e-052118218171520
Pubmed

Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118212502850
Pubmed

A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands.

CLEC4M CD209

1.14e-052118211384997
Pubmed

DC-SIGN and L-SIGN: the SIGNs for infection.

CLEC4M CD209

1.14e-052118218458800
Pubmed

Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118212634366
Pubmed

The nine-repeat DC-SIGNR isoform is associated with increased HIV-RNA loads and HIV sexual transmission.

CLEC4M CD209

1.14e-052118220217198
Pubmed

Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR.

CLEC4M CD209

1.14e-052118215509576
Pubmed

Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers.

BRCA1 ATM

1.14e-052118229665859
Pubmed

SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen.

CLEC4M CD209

1.14e-052118223238564
Pubmed

Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission.

ITGAL CD209

1.14e-052118215222882
Pubmed

Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection.

CLEC4M CD209

1.14e-052118216134084
Pubmed

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells.

RANBP9 ATM

1.14e-052118226943034
Pubmed

Polymorphisms in DC-SIGN and L-SIGN genes are associated with HIV-1 vertical transmission in a Northeastern Brazilian population.

CLEC4M CD209

1.14e-052118222902397
Pubmed

The role of DC-SIGN and DC-SIGNR in HIV and Ebola virus infection: can potential therapeutics block virus transmission and dissemination?

CLEC4M CD209

1.14e-052118212223058
Pubmed

SIGN-R1 and complement factors are involved in the systemic clearance of radiation-induced apoptotic cells in whole-body irradiated mice.

CLEC4M CD209

1.14e-052118226079881
Pubmed

[Analysis of DC-SIGN and DC-SIGNR genetic polymorphism in Chinese Han population].

CLEC4M CD209

1.14e-052118216883544
Pubmed

High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin.

CLEC4M CD209

1.14e-052118215136555
Pubmed

SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.

CLEC4M CD209

1.14e-052118215583012
Pubmed

Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens.

CLEC4M CD209

1.14e-052118215184372
Pubmed

Role for ATM in DNA damage-induced phosphorylation of BRCA1.

BRCA1 ATM

1.14e-052118210866324
Pubmed

Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes.

CLEC4M CD209

1.14e-052118215111305
Pubmed

Internalizing antibodies to the C-type lectins, L-SIGN and DC-SIGN, inhibit viral glycoprotein binding and deliver antigen to human dendritic cells for the induction of T cell responses.

CLEC4M CD209

1.14e-052118216365436
Pubmed

Association of CD209 and CD209L polymorphisms with tuberculosis infection in a Northeastern Brazilian population.

CLEC4M CD209

1.14e-052118224874302
Pubmed

C-type lectin receptor SIGNR1 expressed on peritoneal phagocytic cells with an immature dendritic cell-like phenotype is involved in uptake of oligomannose-coated liposomes and subsequent cell maturation.

CLEC4M CD209

1.14e-052118224491912
Pubmed

Characterization of DC-SIGN/R interaction with human immunodeficiency virus type 1 gp120 and ICAM molecules favors the receptor's role as an antigen-capturing rather than an adhesion receptor.

CLEC4M CD209

1.14e-052118215795245
Pubmed

Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer.

BRCA1 ATM

1.14e-052118216533773
Pubmed

Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching.

BRCA1 ATM

1.14e-052118216204043
Pubmed

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans.

CLEC4M CD209

1.14e-052118227334579
Pubmed

Difference in fine specificity to polysaccharides of Candida albicans mannoprotein between mouse SIGNR1 and human DC-SIGN.

CLEC4M CD209

1.14e-052118222331432
Pubmed

Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM.

USP11 RANBP9

1.14e-052118212084015
Pubmed

Association of DC-SIGN and DC-SIGNR Repeat Regions with Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeastern Iran.

CLEC4M CD209

1.14e-052118227309478
Pubmed

DC-SIGN, DC-SIGNR and LSECtin: C-type lectins for infection.

CLEC4M CD209

1.14e-052118224156700
Pubmed

Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors.

CLEC4M CD209

1.14e-052118235380569
Pubmed

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.

CLEC4M CD209

1.14e-052118215496474
Pubmed

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.

BRCA1 ATM

1.14e-052118210550055
Pubmed

Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis.

BRCA1 ATM

1.14e-052118220175908
Pubmed

Interaction of acute lymphopblastic leukemia cells with C-type lectins DC-SIGN and L-SIGN.

CLEC4M CD209

1.14e-052118218375037
Pubmed

Mutations in CPAMD8 Cause a Unique Form of Autosomal-Recessive Anterior Segment Dysgenesis.

A2M CPAMD8

1.14e-052118227839872
Pubmed

DC-SIGN and DC-SIGNR genetic diversity among different ethnic populations: potential implications for pathogen recognition and disease susceptibility.

CLEC4M CD209

1.14e-052118217509452
Pubmed

HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN).

CLEC4M CD209

1.14e-052118219833723
Pubmed

[Natural selection of DC-SIGN and its homologues L-SIGN and mSIGNR1 in pathogen recognition and innate immunity].

CLEC4M CD209

1.14e-052118216386217
Pubmed

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.

CLEC4M CD209

1.14e-052118211337487
Pubmed

COVID-19, Renin-Angiotensin System and Endothelial Dysfunction.

CLEC4M CD209

1.14e-052118232660065
Pubmed

SIGNR1-mediated phagocytosis, but not SIGNR1-mediated endocytosis or cell adhesion, suppresses LPS-induced secretion of IL-6 from murine macrophages.

CLEC4M CD209

1.14e-052118225226443
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CPAMD8 DAPK1 ACTN4 TRIM21 GMPR2 BUD23 TYROBP KMT2C NOL4L POGLUT1 COL21A1 NLE1 WDR41 DAAM1 DOP1B

3.32e-0512931181515342556
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PPP4R1 AMPD2 NCKAP1 USP11 IARS1 ETF1 RANBP9 ACTN4 GMPR2 LDHA IQGAP1 PRMT6 PPP2R1B APPL1 ZW10 HECTD1

3.38e-0514551181622863883
Pubmed

Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study.

BRCA1 ATM

3.42e-053118215084244
Pubmed

Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

NDC80 ZW10

3.42e-053118216732327
Pubmed

Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies.

CLEC4M CD209

3.42e-053118234464958
Pubmed

A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.

BRCA1 ATM

3.42e-053118212773400
Pubmed

The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases.

RANBP9 TYRO3

3.42e-053118215964779
Pubmed

Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniae.

CLEC4M CD209

3.42e-053118218343501
Pubmed

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.

BRCA1 ATM

3.42e-053118211114888
Pubmed

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response.

BRCA1 ATM

3.42e-053118210910365
InteractionPDCD4 interactions

NCKAP1 ETF1 THOC2 IQGAP1 PPP2R1B EIF4A1 HECTD1 BTRC

8.22e-061761168int:PDCD4
InteractionFBXO45 interactions

EPHB2 FAT4 USP11 TRIM21 POGLUT1 HECTD1

1.18e-05881166int:FBXO45
InteractionICAM3 interactions

USP11 CLEC4M ITGAL CD209

1.92e-05281164int:ICAM3
InteractionPRDX2 interactions

A2M USP11 RANBP9 U2AF2 TRIM21 LDHA PPP2R1B HECTD1 UTY BTRC

2.07e-0532911610int:PRDX2
InteractionHSP90AB1 interactions

USP11 U2AF2 ACTN4 TRIM21 THOC2 LDHA GOLGA8Q MAP3K5 IQGAP1 TYRO3 KMT2C BRCA1 SCG2 EIF4A1 NR3C2 HECTD1 BTRC

3.49e-0596011617int:HSP90AB1
InteractionMYCBP2 interactions

EPHB2 USP11 DAPK1 TRIM21 IQGAP1 POGLUT1 EIF4A1 APPL1 HECTD1 BTRC

3.96e-0535511610int:MYCBP2
InteractionSGO2 interactions

PPP2R1B BRCA1 NLE1 SGO2 HECTD1

5.96e-05721165int:SGO2
InteractionMAP3K2 interactions

NCKAP1 ACTN4 TRIM21 MAP3K5 BTRC

6.37e-05731165int:MAP3K2
InteractionANPEP interactions

DSC3 RANBP9 ACTN4 DNAH14 POGLUT1 PLCB1 WDR41

6.70e-051741167int:ANPEP
InteractionPRDX1 interactions

USP11 RANBP9 U2AF2 TRIM21 LDHA PPP2R1B BRCA1 ALDH3A1 HECTD1 BTRC

6.84e-0537911610int:PRDX1
CytobandEnsembl 112 genes in cytogenetic band chr15q13

GOLGA8R GOLGA8Q GOLGA8N GOLGA8O

1.34e-041001184chr15q13
Cytoband20q11.21

BPIFB3 NOL4L COMMD7

2.47e-0447118320q11.21
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4E PLCB1 PLCE1

6.85e-0519773832
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M CPAMD8

6.32e-0497721234
GeneFamilyPhospholipases

PLA2G4E PLCB1 PLCE1

7.57e-0442773467
GeneFamilyDyneins, axonemal

DNAH14 DNAH9

2.34e-0317772536
CoexpressionP53_DN.V1_UP

SAP30 PPL MAP3K5 NDC80 SCG2 DAAM1 CXADR PLCE1

2.67e-061941178M2698
CoexpressionGSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP

KIAA0319L ACTN4 KCTD21 IQGAP1 ZBTB44 NDC80 NHS ATM

2.99e-061971178M5347
CoexpressionFERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP

KIF18A LAMA1 GJC1 SAP30 BRCA1 NDC80 SGO2

9.20e-061641177M19957
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

EPHB2 KIF18A DEPDC1 NAALADL2 BRCA1 NDC80 SGO2 RAET1L CLSPN GEN1

1.34e-0540211710MM454
CoexpressionGSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN

PPP4R1 PRR5L ACTN4 ITGAL SAP30 B4GALT5 MAP3K5

3.31e-052001177M4656
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d6.LisOva, CD8+ CD45.1+, Spleen, avg-3

KIF18A NCKAP1 POGK DEPDC1 ITGAL B4GALT5 BRCA1 NDC80 SGO2 CLSPN GEN1

1.10e-0540211411GSM605898_500
CoexpressionAtlasMyeloid Cells, DC.8+.Th, CD11b-FITC CD4-PE MHCII-APC CD11c-eFluor780 CD8-eF, Thymus, avg-3

PRR5L DAPK1 DEPDC1 CLEC4M RTN1 CD209 PRKRA TYROBP NECTIN1 SGO2

7.67e-0541211410GSM605828_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

EPHB2 KIF18A PRTG POGK ETF1 LAMA1 RTN1 SAP30 BRCA1 UTP20 CEP295 DAAM1 CLSPN MAPK10 HECTD1 GEN1

7.69e-0598911416Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasgamma delta T cells, Tgd.vg2+24ahi.e17.Th, TCRd+ Vg2+ CD24+, Fetal Thymus, avg-3

EPHB2 KIF18A USP11 DEPDC1 RASGRP1 BRCA1 NDC80 SGO2 CLSPN GEN1

7.99e-0541411410GSM476660_500
CoexpressionAtlasgamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3

KIF18A NCKAP1 DEPDC1 BRCA1 NDC80 SGO2 CLSPN MAPK10 GEN1 PLCE1

8.82e-0541911410GSM476664_500
CoexpressionAtlasgamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2

EPHB2 KIF18A USP11 DEPDC1 RASGRP1 BRCA1 NDC80 SGO2 CLSPN GEN1

9.35e-0542211410GSM476658_500
CoexpressionAtlasB cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Fetal Liver, avg-1

EPHB2 KIF18A IARS1 DEPDC1 SAP30 BRCA1 NDC80 SGO2 CLSPN GEN1

9.35e-0542211410GSM538357_500
CoexpressionAtlasNK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3

PRR5L POGK ITGAL B4GALT5 TYROBP BRCA1 CLSPN HECTD1 PADI2

1.64e-043671149GSM538309_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

KIF18A DEPDC1 NDC80 SGO2 GEN1

1.86e-04981145gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_1000
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAALADL2 PPL IQGAP1 SCG2 PLCB1 NR3C2 RIMS1 HECTD1

2.88e-081821178a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 BRCA1 NDC80 SGO2 ZW10 CLSPN GEN1

4.36e-081921178e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CEP295 CLSPN GEN1

4.53e-0819311784b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

PRR5L GOLGA8R ACTN4 ITGAL IQGAP1 GOLGA8N TYROBP ATM

5.52e-081981178d7053a898e04478c577381085f615edaad3cdc5b
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

PRR5L GOLGA8R ACTN4 ITGAL IQGAP1 GOLGA8N TYROBP ATM

5.52e-081981178aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAALADL2 IQGAP1 SCG2 PLCB1 RAET1L RIMS1 HECTD1

2.45e-071621177373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

2.56e-0716311775285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellfacs-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C RASGRP1 BRCA1 SGO2 CLSPN PADI2 GEN1

2.78e-071651177ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCellDividing_Macrophages-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CEP295 CLSPN

4.13e-0717511770a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

5.00e-071801177334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

KIF18A DEPDC1 SAP30 BRCA1 NDC80 SGO2 CLSPN

5.58e-071831177f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.01e-0718511779766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.01e-07185117730e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.23e-0718611779feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.23e-07186117789f5b06bc56674af304912d481ac697c7c870904
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SNCAIP NDC80 SGO2 CLSPN GEN1

6.46e-0718711774d12c70c8ed922fbc8f7b139145611203735cab4
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SNCAIP NDC80 SGO2 CLSPN GEN1

6.46e-071871177e46b49b4053d2d0f3e1d2bcdc380f7f8733cbe07
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.46e-0718711779351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.46e-071871177057569c9437219ecc396aa6e673b1178a2273837
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SNCAIP NDC80 SGO2 CLSPN GEN1

6.46e-071871177e851ee46a6b4068a7bd7602ee183c0ace50ee4dd
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 DAPK1 NAALADL2 PLCB1 NR3C2 MAPK10 UTY

6.94e-071891177830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

6.94e-0718911771e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF18A BRCA1 NDC80 SGO2 CEP295 CLSPN GEN1

7.19e-071901177d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF18A DEPDC1 RASGRP1 NDC80 SGO2 CLSPN ITPRIPL1

7.44e-071911177bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

KIF18A DEPDC1 ITGAL NDC80 SGO2 CLSPN ITPRIPL1

8.55e-0719511777e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

A2M PRR5L ITGAL GOLGA8Q RASGRP1 ATM GOLGA8O

8.55e-0719511779990440bda7fac5d00ef80444fab07459be625e1
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A PECAM1 DEPDC1 BRCA1 NDC80 SGO2 CLSPN

8.85e-0719611770644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A PECAM1 DEPDC1 NDC80 SGO2 CEP295 CLSPN

9.16e-0719711771c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ|B_lymphocytes / Location, Cell class and cell subclass

DEPDC1 LDHA BRCA1 NDC80 SGO2 DAAM1 CLSPN

9.47e-07198117721c4762ca8591804cf77a23b64470e60d25c5357
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 NAALADL2 BRCA1 NDC80 SGO2 CLSPN

9.47e-07198117750f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 NAALADL2 BRCA1 NDC80 SGO2 CLSPN

9.47e-071981177dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF18A DSC3 DEPDC1 NDC80 RAET1L CLSPN GEN1

9.47e-071981177f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

DSC3 PLA2G4E LDHA PPL NECTIN1 DAAM1 CXADR

9.80e-0719911776be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCell(5)_Dendritic_cell-(52)_cycling_DCs|(5)_Dendritic_cell / shred on Cell_type and subtype

A2M KIF18A DEPDC1 CD209 BRCA1 NDC80 CLSPN

9.80e-071991177d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PRR5L GOLGA8R ITGAL GOLGA8Q GOLGA8N ATM GOLGA8O

9.80e-071991177df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PRR5L GOLGA8R ITGAL GOLGA8Q GOLGA8N ATM GOLGA8O

9.80e-071991177ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellNon-neuronal-Dividing|World / Primary Cells by Cluster

KIF18A DEPDC1 LDHA BRCA1 NDC80 SGO2 CLSPN

1.01e-06200117750fa7b34a05f2c5ebbc7d113bd8e31326688a231
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

1.01e-0620011778f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

1.01e-062001177a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 NAALADL2 BRCA1 NDC80 SGO2 CLSPN

1.01e-06200117731dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A DEPDC1 NAALADL2 BRCA1 NDC80 SGO2 CLSPN

1.01e-06200117754174a485a82480726fa06efa6e050ddea77cb3c
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PCDHGA6 DAPK1 NHS RIMS1 PADI2 ITPRIPL1 DOP1B

1.01e-06200117761bae10c8b12196d9cee766897971b81cb897191
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

A2M FAT4 PRR5L GOLGA8R ITGAL GOLGA8Q GOLGA8O

1.01e-0620011772281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellNon-neuronal-Dividing-Radial_Glia|World / Primary Cells by Cluster

KIF18A DEPDC1 LDHA BRCA1 NDC80 SGO2 CLSPN

1.01e-062001177ecbbad00e16041a9e1cd88d8bd7279a1b52c0aa4
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

1.01e-0620011771b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

A2M PRR5L ITGAL GOLGA8Q RASGRP1 ATM GOLGA8O

1.01e-062001177f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A GJC1 DEPDC1 NDC80 SGO2 GEN1

1.36e-06132117602491930097b75aaeedab9e8200711b0dc610944
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL TYROBP BRCA1 NDC80 SGO2 PADI2

4.63e-061631176a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C BRCA1 SGO2 CLSPN PADI2 GEN1

4.63e-061631176385b24e18df5ef92108483de312d6c85a1e6d145
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PECAM1 ACTN4 BRCA1 NDC80 SGO2 CLSPN

4.63e-0616311763efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C BRCA1 SGO2 CLSPN PADI2 GEN1

4.63e-0616311768004cc0b3428be08b89957b563cd8799f822d931
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL TYROBP BRCA1 NDC80 SGO2 PADI2

4.63e-061631176eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 RAET1L CLSPN

5.32e-06167117650c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LDHA DNAH14 PPL ATM UTY CXADR

5.50e-0616811765e721268f0baa51d3f640f7f4c41db769ebef210
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 RAET1L CLSPN

5.50e-061681176d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CEP295

5.69e-061691176b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A DEPDC1 NDC80 SGO2 CLSPN GEN1

5.69e-061691176e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

6.51e-061731176a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A DEPDC1 NDC80 SGO2 CEP295 RIMS1

6.73e-0617411767b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 NDC80 SGO2 CLSPN GEN1

6.95e-061751176876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A TYROBP NDC80 CLSPN PADI2 GEN1

7.18e-0617611761f8d5a48fedbb4c86272c9b5a0f1ef573350357b
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF18A DEPDC1 SAP30 NDC80 SGO2 CLSPN

7.66e-061781176c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1 NOL4L BRCA1 NDC80 SGO2 CLSPN

7.91e-06179117654621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

7.91e-06179117654191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

A2M CPAMD8 FAT4 PECAM1 SNCAIP PLCB1

7.91e-0617911762a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

8.17e-0618011765e1680088065be14447d5d5465f91f7edd071a1e
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

8.43e-0618111760c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

8.43e-061811176f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

8.43e-061811176ac1ee313910c05b1b3cb497bae14565464919c21
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A NCKAP1 DEPDC1 NDC80 CEP295 CLSPN

8.70e-06182117639f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGA6 GJC1 COL6A5 DEPDC1 BRCA1 NDC80

8.70e-061821176c84f44391932080df31c8765e363c3dff64b2bd1
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M KIF18A PECAM1 CC2D2B NDC80 SGO2

8.97e-06183117652af3c943116073c8ddd207b664342960b88929b
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

8.97e-06183117609c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FAT4 PDE1C LAMA1 DNAH9 PLCE1

9.26e-0618411762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DEPDC1 BRCA1 NDC80 SGO2 CLSPN GEN1

9.26e-061841176f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FAT4 PDE1C LAMA1 DNAH9 PLCE1

9.26e-061841176ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FAT4 PDE1C LAMA1 DNAH9 PLCE1

9.26e-0618411762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

A2M ITGAL GOLGA8Q IQGAP1 TYROBP GOLGA8O

9.26e-061841176791f1bcb954aadc63d4117c400537d036f68734d
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

9.55e-0618511760ae9c646679c69a553eda670aef0e0495feb0286
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIF18A DEPDC1 NDC80 SGO2 CEP295 CLSPN

9.84e-06186117686d145f965c311189e7996390eef491642417c5c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

1.01e-051871176e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 PPP4R1 DAPK1 NAALADL2 PPL PLCB1

1.01e-05187117687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

1.01e-051871176cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 PPP4R1 DAPK1 NAALADL2 PPL PLCB1

1.01e-05187117642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 PPP4R1 DAPK1 NAALADL2 PPL PLCB1

1.01e-05187117664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

A2M CPAMD8 FAT4 PECAM1 SNCAIP PLCB1

1.01e-05187117640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M PRR5L ITGAL NAALADL2 NOL4L TRBV3-1

1.01e-051871176cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SAP30 SNCAIP BRCA1 SGO2

1.01e-051871176a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SAP30 SNCAIP BRCA1 SGO2

1.01e-05187117638ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 SAP30 SNCAIP BRCA1 SGO2

1.01e-051871176dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

KIF18A DEPDC1 NDC80 SGO2 CLSPN GEN1

1.05e-051881176b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

1.08e-051891176bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

1.08e-05189117696f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

KIF18A DEPDC1 BRCA1 NDC80 SGO2 CLSPN

1.11e-051901176005967c540418b85311308072a07c684f4296aef
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

DSC3 NCKAP1 PPL NECTIN1 NHS ALDH3A1

1.11e-051901176ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A DEPDC1 SGO2 CEP295 GEN1 PLCE1

1.11e-0519011767be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP9 DEPDC1 BRCA1 SGO2 CEP295 PLCE1

1.11e-0519011760adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A DEPDC1 BRCA1 SGO2 CEP295 PLCE1

1.11e-051901176250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

A2M CPAMD8 PECAM1 GJC1 NHS RIMS1

1.11e-051901176a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP9 DEPDC1 BRCA1 SGO2 CEP295 PLCE1

1.11e-05190117605455775845f4ded5c27e7b83242078d23162aaf
Diseaseextrapulmonary tuberculosis (is_implicated_in)

CLEC4M CD209

4.05e-0531092DOID:0050598 (is_implicated_in)
DiseaseAdenocarcinoma of prostate

EPHB2 BRCA1 ATM

5.34e-05201093C0007112
DiseaseCarcinoma, Granular Cell

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0205644
DiseaseAdenocarcinoma, Tubular

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0205645
DiseaseAdenocarcinoma, Oxyphilic

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0205642
DiseaseCarcinoma, Cribriform

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0205643
DiseaseAdenocarcinoma, Basal Cell

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0205641
DiseaseAdenocarcinoma

FAT4 DAPK1 GMPR2 KMT2C PLCE1

7.26e-051161095C0001418
DiseaseBreast Cancer, Familial

BRCA1 ATM GEN1

1.85e-04301093C0346153
DiseaseCataract

CPAMD8 ATM ALDH3A1

3.48e-04371093C0086543
DiseaseAdenoid Cystic Carcinoma

DAPK1 KMT2C BRCA1 ATM

5.26e-041001094C0010606
DiseaseLiver carcinoma

A2M KIF18A DEPDC1 CLEC4M IQGAP1 KMT2C NDC80 ATM

6.00e-045071098C2239176
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

A2M MAP3K5

1.20e-03141092DOID:10976 (biomarker_via_orthology)
Diseasetumor necrosis factor beta measurement

EPHB2 NAALADL2

1.38e-03151092EFO_0008308
Diseasepreeclampsia, hypertension, pregnancy-induced

ACTN4 PLCE1

1.57e-03161092EFO_0000668, MONDO_0024664
Diseasestomach cancer (is_marker_for)

KIF18A BRCA1 NDC80 ATM

1.93e-031421094DOID:10534 (is_marker_for)
DiseaseMYELODYSPLASTIC SYNDROME

DAPK1 BRCA1 PLCB1

1.98e-03671093C3463824
DiseaseMalignant neoplasm of breast

DSC3 BRCA1 PLCB1 NHS NLE1 UTP20 APPL1 ATM CLSPN DNAH9 GEN1

2.10e-03107410911C0006142
DiseaseProstate cancer, familial

EPHB2 BRCA1 ATM

2.15e-03691093C2931456
DiseaseMental Depression

A2M DRD1 LDHA BRCA1 NR3C2

2.57e-032541095C0011570
DiseaseBREAST CANCER

BRCA1 ATM

2.71e-03211092114480
Diseasehyperglycemia (biomarker_via_orthology)

DRD1 LDHA

2.71e-03211092DOID:4195 (biomarker_via_orthology)
Diseasecolorectal cancer (is_marker_for)

KIF18A BRCA1 NDC80 ATM

2.78e-031571094DOID:9256 (is_marker_for)
Diseaseplatelet reactivity measurement, response to clopidogrel

NR3C2 PLCE1

3.25e-03231092EFO_0004985, GO_1903493
DiseaseImmunologic Deficiency Syndromes

RASGRP1 ATM

3.25e-03231092C0021051
DiseasePseudoaphakia

ATM ALDH3A1

3.54e-03241092C0524524
Diseasestomach carcinoma (is_marker_for)

KMT2C BRCA1

3.54e-03241092DOID:5517 (is_marker_for)
DiseaseLens Opacities

ATM ALDH3A1

3.54e-03241092C1510497
Diseaselung non-small cell carcinoma (is_marker_for)

PECAM1 BRCA1 NDC80 ATM

3.62e-031691094DOID:3908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
NQILPYIKELVSDTN

PPP2R1B

336

P30154
LQQTVEYEGITPELK

C2orf16

256

Q68DN1
SLEEPYEIQLNQVIF

DAPK1

841

P53355
LQLYPENSEQLELIT

BUD23

161

O43709
NQYIELDINPIVKSV

BPIFB3

236

P59826
PVEKTPQTQQDELYI

ALDH3A1

86

P30838
PTYQELEQEINTLKA

RASGRP1

746

O95267
LYPKIIQDIETIESN

BTRC

271

Q9Y297
EVTPQYQLLVEVEDK

FAT4

211

Q6V0I7
SIVDYKPNLDLLEQQ

ACTN4

696

O43707
QPIQQILEIVLDASY

ASB15

86

Q8WXK1
VSQEELTALLYKPQE

BRWD3

1121

Q6RI45
LPEKSKQQEIYQELT

CD209

206

Q9NNX6
YDTDVSLEKIQPITQ

DRD1

426

P21728
QQLAEKPLETRTYEQ

AMPD2

271

Q01433
YKNITVNLTPELAQV

B4GALT5

371

O43286
KIQSIQPEEIIYFET

CC2D2B

1291

Q6DHV5
PLKNQEVEDIVIYLS

EFCAB12

231

Q6NXP0
VLDYLNETQQLTPEI

A2M

986

P01023
TVDPKNKYQELINDI

IQGAP1

1471

P46940
EAIETTQQLYPSLLE

RANBP9

421

Q96S59
LLISYPQDDQKLQES

CRPPA

411

A4D126
DQLIYNLLKEEQTPQ

LDHA

6

P00338
YIPVKTDLSNVQELL

POGLUT1

311

Q8NBL1
NQESYEKSEPLLITQ

PCDHGA6

781

Q9Y5G7
TQSLIQLYSDIIPEE

KMT2C

3586

Q8NEZ4
KNLPLEDQITLIQYS

NR3C2

791

P08235
FYQVQPLIEALQEKE

KCTD21

86

Q4G0X4
NVEGLPEEEYTKQNL

KCTD21

191

Q4G0X4
TPQKTLEEFQDVYLV

MAPK10

131

P53779
SEPYNQILTIQLTDK

MGAM2

1781

Q2M2H8
VLDSDIIVQKIQPYT

KIAA0319L

821

Q8IZA0
QLNDSLSKELQPIVY

KIF18A

691

Q8NI77
LDVIPLELYSEVQTQ

DOP1B

486

Q9Y3R5
NNISKQIYLSENPEE

APPL1

371

Q9UKG1
AEYQTSIQEKLPLII

EPHB2

531

P29323
IDVQQVSLVINYDLP

EIF4A1

336

P60842
YLLSEKQVSQLPVET

PLXNA3

476

P51805
EVVKLQNDPQLEAEY

PPL

1056

O60437
FESNSLKYLQPEQIE

PDE1C

11

Q14123
KEPLNSDVQYTEVQV

PECAM1

681

P16284
QTLIIQKEELNTDLY

GOLGA8Q

136

H3BV12
EILQVPSYLQTAVEK

DEPDC1

681

Q5TB30
EQLEQILEAIPQVKY

GMPR2

111

Q9P2T1
VSYNELTFIPNEIQK

LRRC63

421

Q05C16
VLNLLENPIQEKSEY

LRGUK

331

Q96M69
SQLQVLDVVVYKPLN

POGK

501

Q9P215
LKAQQVQAPVELYSD

PADI2

451

Q9Y2J8
TNIYVKNLPVDVDEQ

PABPC1L

191

Q4VXU2
IYQSSQDEPIALDKQ

NOL4L

291

Q96MY1
YNQATQEIAKPSELL

NCKAP1

726

Q9Y2A7
SYLQLEELVKQVVSP

PRR5L

206

Q6MZQ0
YNSKLVINQIIPEDD

PRTG

376

Q2VWP7
EVYNIILESKSEPQV

RIMS1

671

Q86UR5
PIYLTINVKDDVSNQ

PLA2G4E

511

Q3MJ16
LVYLVSQAPDQEQLT

ITPRIPL1

376

Q6GPH6
NYPSQEELIKVVDVE

BRCA1

1521

P38398
ITIVENKYPSVLNLN

DAAM1

861

Q9Y4D1
PLVYEQVEVQKQVLD

ATM

1526

Q13315
DELPKNDLITYLQKN

HECTD1

1906

Q9ULT8
EVETPKNELYNITVL

DSC3

536

Q14574
NIAVKPDQIQYTELS

GJC1

291

P36383
PADNQKVDQVIILYS

CXADR

61

P78310
LQQLSQIKYQDTTEP

COL6A5

1826

A8TX70
YLQKTQQLSPEVERE

CPAMD8

1161

Q8IZJ3
KGNQTENVYIELTLP

COMMD7

166

Q86VX2
VTLYIDDQQIENKPL

COL21A1

361

Q96P44
ALLYLNEPVQVEQDT

PRMT6

321

Q96LA8
ETDPAYQNIIVNLLT

DNAH14

656

Q0VDD8
DQLLQEDYKVNTSVP

GEN1

741

Q17RS7
QTIELLKTYEQELPE

DNAH9

1171

Q9NYC9
QTLIIQKEELNTDLY

GOLGA8R

136

I6L899
QTLIIQKEELNTDLY

GOLGA8O

136

A6NCC3
TAQYPELNALQEELK

GPX5

76

O75715
YINEANLIPEKTDLQ

CEP295

2051

Q9C0D2
YELKVSVQNEAPLQA

CDH15

336

P55291
LYKVIQDSNNELLEP

FAM126B

41

Q8IXS8
QPSYLSINNEVEEKT

MAP3K5

571

Q99683
QLDIEETEQSKLPQY

MRPS27

316

Q92552
LELEITLSQEQIQKY

RTN1

661

Q16799
AVETEKVLDIIYQPQ

NLE1

81

Q9NVX2
TYSEQDPLLKNLSQE

UTP20

2681

O75691
AKEAYEQLLQTENLP

UTY

221

O14607
NYEEVLLSNIKPIQT

TDRD3

596

Q9H7E2
TKVQDVVPQALLDQY

PPP4R1

611

Q8TF05
QDIDTPEVDLYQLQV

SAP30

141

O75446
LEYLNLNTVPVEENK

TDRD15

1686

B5MCY1
EVKQKEENNTDLPYL

NHS

1151

Q6T4R5
ESQENIKELQLPLSY

PLCE1

1386

Q9P212
QIQENYQKPLEELEV

LAMA1

1731

P25391
KPLDSQSIYQLIEIS

SCG2

341

P13521
DEILDVPYIKSSQQL

SNCAIP

151

Q9Y6H5
DNLLPNQKDKVTIYE

SGO2

546

Q562F6
YQNLKVLIDPVSVQD

IARS1

781

P41252
YPINILIQDQEDSTL

ITGAL

921

P20701
PEKSKLQEIYQELTE

CLEC4M

196

Q9H2X3
LIPKQETYDQADVIV

CLCA3P

91

Q9Y6N3
EKSLYQENLEAQVKP

CLSPN

116

Q9HAW4
KQRITETESPYQELQ

TYROBP

81

O43914
QIQKYDNLITPVVDS

THOC2

586

Q8NI27
EPNQETVIYKNQDLS

SPEM3

811

A0A1B0GUW6
PDEENITSYLQLIEK

SAMD4B

491

Q5PRF9
SLLDPNAIYQELQKV

SLC27A1

561

Q6PCB7
LVPDYLNQEQEETLV

ZBTB44

526

Q8NCP5
IQNIAIELTKPQYLS

VPS13C

326

Q709C8
LTEQLLDIQLENYTP

RAET1L

101

Q5VY80
VPLEEAAQEYQEKLQ

TRIM21

126

P19474
VQVLIEKYEPNNSLA

PLCB1

271

Q9NQ66
IPNTDYIQLLSEIAK

PRKRA

236

O75569
LPNYLNDDQVKELLT

U2AF2

266

P26368
FSYNNKELIINETVP

TRBV3-1

66

A0A576
VQLSKLLQENVPSYE

PIGG

356

Q5H8A4
PVNENQIESKAAYVL

USP11

911

P51784
AVVQNLDQLYIPVSE

TYRO3

81

Q06418
EEQTQNPYTELLVLK

WDR41

26

Q9HAD4
IPTNSSKLQQYEEII

ZW10

351

O43264
QGTEEEKILYLTPEQ

ETF1

336

P62495
QTLIIQKEELNTDLY

GOLGA8N

136

F8WBI6
DPQLYQEILKTIQAE

NAALADL2

161

Q58DX5
QVYVPLKELLNETEE

NDC80

456

O14777
KESLTLNVQYEPEVT

NECTIN1

236

Q15223