Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC4 YTHDC2 RFC2 ABCC6 DMC1 ABCG4 ATAD3C ABCB8 MACF1 KIF5B ATP2A1 ATP2A2 DNAH8 DHX29 ATP4A DDX11L8	3.23e-06	441	183	16	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC4 YTHDC2 RFC2 ABCC6 DMC1 ABCG4 ATAD3C ACSBG1 ABCB8 MACF1 KIF5B ATP2A1 ATP2A2 DNAH8 DHX29 HSPA4 ATP4A DDX11L8	1.47e-05	614	183	18	GO:0140657
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC4 ABCC6 ABCG4 ABCB8 ATP2A1 ATP2A2 ATP4A	6.57e-05	109	183	7	GO:0042626
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C NFATC4 FAM72A VPS13A FAM72B	1.19e-09	14	181	6	GO:0031547
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor-activated receptor activity	FAM72D FAM72C FAM72A FAM72B	5.74e-09	4	181	4	GO:0031551
GeneOntologyBiologicalProcess	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	2.85e-08	5	181	4	GO:0031549
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	1.97e-07	7	181	4	GO:0031548
GeneOntologyBiologicalProcess	negative regulation of signaling receptor activity	FAM72D CALCR FAM72C FAM72A FAM72B	9.57e-06	33	181	5	GO:2000272
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	8.16e-09	4	179	4	IPR026768
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	8.16e-09	4	179	4	PF14976
Domain	NACHT	NLRP12 TEP1 NLRP14 NLRC5 NLRC3	2.24e-06	23	179	5	PS50837
Domain	NACHT_NTPase	NLRP12 TEP1 NLRP14 NLRC5 NLRC3	2.24e-06	23	179	5	IPR007111
Domain	LRR_6	NLRP12 FBXL13 NLRP14 CEP78 NLRC5 NLRC3	1.40e-05	55	179	6	PF13516
Domain	Leu-rich_rpt	NLRP12 FBXL13 LRIT3 NLRP14 CEP78 SLIT3 TLR5 LRRC56 NLRC5 FBXO39 NLRC3	6.32e-05	271	179	11	IPR001611
Domain	AAA	ABCC4 RFC2 ABCC6 DMC1 ABCG4 ATAD3C ABCB8 DNAH8	7.56e-05	144	179	8	SM00382
Domain	AAA+_ATPase	ABCC4 RFC2 ABCC6 DMC1 ABCG4 ATAD3C ABCB8 DNAH8	7.56e-05	144	179	8	IPR003593
Domain	Ribosomal_L10e_CS	RPL10L RPL10	9.13e-05	2	179	2	IPR018255
Domain	DUF4062	TEP1 NWD2	9.13e-05	2	179	2	PF13271
Domain	Aquaporin_12	AQP12A AQP12B	9.13e-05	2	179	2	IPR023265
Domain	NPY4_rcpt	NPY4R2 NPY4R	9.13e-05	2	179	2	IPR001933
Domain	Ribosomal_L10e	RPL10L RPL10	9.13e-05	2	179	2	IPR001197
Domain	DUF4062	TEP1 NWD2	9.13e-05	2	179	2	IPR025139
Domain	RIBOSOMAL_L10E	RPL10L RPL10	9.13e-05	2	179	2	PS01257
Domain	Ribosomal_L10e/L16	RPL10L RPL10	2.72e-04	3	179	2	IPR016180
Domain	-	RPL10L RPL10	2.72e-04	3	179	2	3.90.1170.10
Domain	Ribosomal_L16	RPL10L RPL10	2.72e-04	3	179	2	PF00252
Domain	Aquaporin_11/12	AQP12A AQP12B	2.72e-04	3	179	2	IPR016697
Domain	P-type_ATPase_IIA	ATP2A1 ATP2A2	2.72e-04	3	179	2	IPR005782
Domain	-	NLRP12 FBXL13 LRIT3 NLRP14 CEP78 SLIT3 TLR5 LRRC56 NLRC5 FBXO39 NLRC3	2.79e-04	321	179	11	3.80.10.10
Domain	-	NLRP12 ABCC4 GBP7 APAF1 YTHDC2 RFC2 TEP1 ABCC6 DMC1 ABCG4 NLRP14 NWD2 TRANK1 ATAD3C ABCB8 NLRC5 DNAH8 DHX29	3.05e-04	746	179	18	3.40.50.300
Domain	L_dom-like	NLRP12 FBXL13 LRIT3 NLRP14 CEP78 SLIT3 TLR5 LRRC56 NLRC5 FBXO39 NLRC3	3.35e-04	328	179	11	IPR032675
Domain	ATPase_P-typ_TM_dom	ATP2A1 ATP2A2 ATP4A	4.42e-04	16	179	3	IPR023298
Domain	-	ATP2A1 ATP2A2 ATP4A	4.42e-04	16	179	3	1.20.1110.10
Domain	F-box	FBXL13 FBXO30 FBXO10 FBXL18 FBXO39	4.57e-04	67	179	5	PF00646
Domain	P-loop_NTPase	NLRP12 ABCC4 GBP7 APAF1 YTHDC2 RFC2 TEP1 ABCC6 DMC1 ABCG4 NLRP14 NWD2 TRANK1 ATAD3C ABCB8 NLRC5 KIF5B DNAH8 DHX29	5.18e-04	848	179	19	IPR027417
Domain	ATPase_P-typ_cation-transptr_C	ATP2A1 ATP2A2 ATP4A	5.33e-04	17	179	3	IPR006068
Domain	Cation_ATPase_C	ATP2A1 ATP2A2 ATP4A	5.33e-04	17	179	3	PF00689
Domain	Cation_ATPase_N	ATP2A1 ATP2A2 ATP4A	6.35e-04	18	179	3	PF00690
Domain	Cation_ATPase_N	ATP2A1 ATP2A2 ATP4A	6.35e-04	18	179	3	SM00831
Domain	FBOX	FBXL13 FBXO30 FBXO10 FBXL18 FBXO39	6.37e-04	72	179	5	PS50181
Domain	ABC_transporter_CS	ABCC4 ABCC6 ABCG4 ABCB8	6.87e-04	42	179	4	IPR017871
Domain	ATPase_P-typ_cation-transptr_N	ATP2A1 ATP2A2 ATP4A	7.49e-04	19	179	3	IPR004014
Domain	F-box_dom	FBXL13 FBXO30 FBXO10 FBXL18 FBXO39	7.67e-04	75	179	5	IPR001810
Domain	RCC1	IBTK HERC2 HERC1	8.75e-04	20	179	3	PF00415
Domain	NFAT	NFATC3 NFATC4	8.96e-04	5	179	2	IPR008366
Domain	RCC1_1	IBTK HERC2 HERC1	1.01e-03	21	179	3	PS00625
Domain	RCC1_2	IBTK HERC2 HERC1	1.01e-03	21	179	3	PS00626
Domain	RCC1_3	IBTK HERC2 HERC1	1.01e-03	21	179	3	PS50012
Domain	ABC_tran	ABCC4 ABCC6 ABCG4 ABCB8	1.14e-03	48	179	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCC4 ABCC6 ABCG4 ABCB8	1.14e-03	48	179	4	PS50893
Domain	-	IBTK HERC2 HERC1	1.17e-03	22	179	3	2.130.10.30
Domain	Reg_chr_condens	IBTK HERC2 HERC1	1.17e-03	22	179	3	IPR000408
Domain	ABC_TRANSPORTER_1	ABCC4 ABCC6 ABCG4 ABCB8	1.23e-03	49	179	4	PS00211
Domain	Spectrin	SPTBN4 SPTBN5 MACF1	1.33e-03	23	179	3	PF00435
Domain	ACTININ_2	SPTBN4 SPTBN5 MACF1	1.33e-03	23	179	3	PS00020
Domain	ACTININ_1	SPTBN4 SPTBN5 MACF1	1.33e-03	23	179	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN4 SPTBN5 MACF1	1.33e-03	23	179	3	IPR001589
Domain	RCC1/BLIP-II	IBTK HERC2 HERC1	1.33e-03	23	179	3	IPR009091
Domain	ABC_transporter-like	ABCC4 ABCC6 ABCG4 ABCB8	1.33e-03	50	179	4	IPR003439
Domain	ABC_membrane	ABCC4 ABCC6 ABCB8	1.51e-03	24	179	3	PF00664
Domain	FBOX	FBXO30 FBXO10 FBXL18 FBXO39	1.54e-03	52	179	4	SM00256
Domain	APC_su10/DOC_dom	ZZEF1 HERC2	1.86e-03	7	179	2	IPR004939
Domain	DOC	ZZEF1 HERC2	1.86e-03	7	179	2	PS51284
Domain	ANAPC10	ZZEF1 HERC2	1.86e-03	7	179	2	PF03256
Domain	APC10	ZZEF1 HERC2	1.86e-03	7	179	2	SM01337
Domain	CYCLINS	CCNO CCNA1 CCNI	2.38e-03	28	179	3	PS00292
Domain	ABC_TM1F	ABCC4 ABCC6 ABCB8	2.38e-03	28	179	3	PS50929
Domain	ABC1_TM_dom	ABCC4 ABCC6 ABCB8	2.38e-03	28	179	3	IPR011527
Domain	Spectrin_repeat	SPTBN4 SPTBN5 MACF1	2.63e-03	29	179	3	IPR002017
Pubmed	Fam72a enforces error-prone DNA repair during antibody diversification.	FAM72D FAM72C FAM72A FAM72B	8.27e-10	4	188	4	34819671
Pubmed	Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.	FAM72D FAM72C FAM72A FAM72B	4.12e-09	5	188	4	19755123
Pubmed	All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.	FAM72D FAM72C FAM72A FAM72B	4.12e-09	5	188	4	26206078
Pubmed	FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.	FAM72D FAM72C FAM72A FAM72B	1.23e-08	6	188	4	34819670
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	FAM72D FAM72C FAM72A FAM72B	1.08e-06	15	188	4	1741163
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	IPO5 ACACA ITPRID2 CDC42BPB HEATR6 SBF1 ANAPC1 HERC2 ATP2A2	1.71e-06	202	188	9	33005030
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRPF31 NEPRO NSD1 IST1 YTHDC2 ITPRID2 ODF2 RFC2 CDC42BPB SBF1 EHMT2 ANAPC1 CDYL2 MACF1 RAI14 MCAT DAAM1 HERC2 TMCO1 ATP2A2 DHX29 EDRF1 RPL10	6.84e-06	1497	188	23	31527615
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZZEF1 IBTK TRANK1 SBF1 USP38 ACSBG1 SYNJ2 SLIT3 LHFPL2 RAI14 DIXDC1 DAAM1 ANKS3	6.92e-06	529	188	13	14621295
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXL13 FBXO30 FBXO10 FBXL18 FBXO39	2.04e-05	61	188	5	15520277
Pubmed	The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.	PHF20 EHMT2 CDYL2	2.48e-05	11	188	3	33097091
Pubmed	Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.	ATP2A1 ATP2A2	2.91e-05	2	188	2	12556521
Pubmed	Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.	ATP2A1 ATP2A2	2.91e-05	2	188	2	19644701
Pubmed	Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3).	KCNJ10 KCNJ15	2.91e-05	2	188	2	8995301
Pubmed	Association of genetic variants with ischemic stroke in Japanese individuals with or without metabolic syndrome.	SPTBN5 CLEC16A	2.91e-05	2	188	2	20043139
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.	ATP2A1 ATP2A2	2.91e-05	2	188	2	14638697
Pubmed	Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.	APAF1 HSPA4	2.91e-05	2	188	2	22143029
Pubmed	Genetic analysis of the aquaporin water channels AQP12A and AQP12B in patients with chronic pancreatitis.	AQP12A AQP12B	2.91e-05	2	188	2	36167651
Pubmed	Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.	ATP2A1 ATP2A2	2.91e-05	2	188	2	15718407
Pubmed	SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.	ATP2A1 ATP2A2	2.91e-05	2	188	2	11402072
Pubmed	Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.	NFATC3 NFATC4	2.91e-05	2	188	2	7749981
Pubmed	Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons.	NFATC3 NFATC4	2.91e-05	2	188	2	22977251
Pubmed	The Dispensable Roles of X-Linked Ubl4a and Its Autosomal Counterpart Ubl4b in Spermatogenesis Represent a New Evolutionary Type of X-Derived Retrogenes.	UBL4B UBL4A	2.91e-05	2	188	2	34249105
Pubmed	Specific localization of an inwardly rectifying K(+) channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K(+) recycling for the H(+)-K(+)-pump.	KCNJ10 KCNJ15	2.91e-05	2	188	2	11927671
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.	ATP2A1 ATP2A2	2.91e-05	2	188	2	10603953
Pubmed	Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.	AQP12A AQP12B	2.91e-05	2	188	2	15809071
Pubmed	Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.	ATP2A1 ATP2A2	2.91e-05	2	188	2	34769190
Pubmed	Ubl4b, an X-derived retrogene, is specifically expressed in post-meiotic germ cells in mammals.	UBL4B UBL4A	2.91e-05	2	188	2	16872915
Pubmed	Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.	ATP2A1 ATP2A2	2.91e-05	2	188	2	18953100
Pubmed	Genetic or pharmacologic disruption of the calcineurin-nuclear factor of activated T-cells axis prevents social stress-induced voiding dysfunction in a murine model.	NFATC3 NFATC4	2.91e-05	2	188	2	24909609
Pubmed	SERCA overexpression reduces hydroxyl radical injury in murine myocardium.	ATP2A1 ATP2A2	2.91e-05	2	188	2	16798816
Pubmed	Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.	AQP12A AQP12B	2.91e-05	2	188	2	19726746
Pubmed	Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic Arborization and Axon Outgrowth in the Developing Brain.	MACF1 NEUROD6	2.91e-05	2	188	2	26526844
Pubmed	Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.	ATP2A1 ATP2A2	2.91e-05	2	188	2	12975374
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	LDB1 KCNJ10 ATP2A2 CLEC16A HSPA4 ATP4A	3.10e-05	110	188	6	27889896
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRPF31 ACACA APAF1 YTHDC2 RFC2 FANCD2 EHMT2 USO1 KIF5B TMCO1 GMPPB DNAH8 DHX29 RPL10	3.24e-05	704	188	14	29955894
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ACACA CTC1 GLB1L2 DMC1 TRANK1 AFAP1L2 DPH5 GUCY2C VPS13A NLRC5 ULK4 HERC2	5.16e-05	552	188	12	10737800
Pubmed	Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.	ACACA SBF1 HERC2 HSPA4	7.16e-05	41	188	4	19343720
Pubmed	Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.	ATP2A1 ATP2A2	8.69e-05	3	188	2	27055500
Pubmed	NFATc3 and NFATc4 are required for cardiac development and mitochondrial function.	NFATC3 NFATC4	8.69e-05	3	188	2	12750314
Pubmed	Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart.	ATP2A1 ATP2A2	8.69e-05	3	188	2	25615793
Pubmed	Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.	ATP2A1 ATP2A2	8.69e-05	3	188	2	15972723
Pubmed	Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation.	NFATC3 NFATC4	8.69e-05	3	188	2	25422138
Pubmed	Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.	ATP2A1 ATP2A2	8.69e-05	3	188	2	16754798
Pubmed	Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure.	NLRP12 NLRC3	8.69e-05	3	188	2	26763980
Pubmed	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.	NPY4R2 NPY4R	8.69e-05	3	188	2	8643460
Pubmed	Disparate Regulatory Mechanisms Control Fat3 and P75NTR Protein Transport through a Conserved Kif5-Interaction Domain.	FAT3 KIF5B	8.69e-05	3	188	2	27788242
Pubmed	Hsp70 acetylation prevents caspase-dependent/independent apoptosis and autophagic cell death in cancer cells.	APAF1 HSPA4	8.69e-05	3	188	2	28627586
Pubmed	Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.	KCNJ10 KCNJ15	8.69e-05	3	188	2	34205849
Pubmed	Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function.	KCNJ10 KCNJ15	8.69e-05	3	188	2	17122384
Pubmed	Phospholamban domain IB forms an interaction site with the loop between transmembrane helices M6 and M7 of sarco(endo)plasmic reticulum Ca2+ ATPases.	ATP2A1 ATP2A2	8.69e-05	3	188	2	11526231
Pubmed	The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.	ATP2A1 ATP2A2	8.69e-05	3	188	2	16410239
Pubmed	Coordinate regulation of SR Ca(2+)-ATPase and phospholamban expression in developing murine heart.	ATP2A1 ATP2A2	8.69e-05	3	188	2	9038922
Pubmed	Specific effects of endurance and sprint training on protein expression of calsequestrin and SERCA in mouse skeletal muscle.	ATP2A1 ATP2A2	8.69e-05	3	188	2	22466636
Pubmed	Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.	AQP12A AQP12B SFTPA1	1.00e-04	17	188	3	26847765
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 ACACA CTC1 NSD1 C15orf39 UBL4A CEP192 TEP1 ZZEF1 CDC42BPB SBF1 LRRC56 NLRC5 AP1G2 ULK4 HERC2 HERC1	1.14e-04	1105	188	17	35748872
Pubmed	Meioc maintains an extended meiotic prophase I in mice.	YTHDC2 DMC1 CCNA1	1.41e-04	19	188	3	28380054
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	STON1 ACACA YTHDC2 CEP192 IBTK USO1 MACF1	1.50e-04	209	188	7	36779422
Pubmed	Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.	NFATC3 ATP2A1 ATP2A2	1.66e-04	20	188	3	18978355
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PRPF31 ACACA YTHDC2 CDC42BPB IBTK SBF1 CEP78 SYNJ2 ANAPC1 MACF1 TMCO1 ATP2A2 DHX29	1.71e-04	724	188	13	36232890
Pubmed	Nuclear factor of activated T cells is activated in the endothelium of retinal microvessels in diabetic mice.	NFATC3 NFATC4	1.73e-04	4	188	2	25918731
Pubmed	Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT.	NFATC3 NFATC4	1.73e-04	4	188	2	9660947
Pubmed	NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis.	NFATC3 NFATC4	1.73e-04	4	188	2	26527057
Pubmed	Negative regulation of the Apaf-1 apoptosome by Hsp70.	APAF1 HSPA4	1.73e-04	4	188	2	10934467
Pubmed	Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase.	NLRP12 HSPA4	1.73e-04	4	188	2	17947705
Pubmed	Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na+ Channel (ENaC).	KCNJ10 KCNJ15	1.73e-04	4	188	2	37909221
Pubmed	Insulin receptor substrate proteins create a link between the tyrosine phosphorylation cascade and the Ca2+-ATPases in muscle and heart.	ATP2A1 ATP2A2	1.73e-04	4	188	2	9295312
Pubmed	HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.	NFATC3 NFATC4	1.73e-04	4	188	2	16260021
Pubmed	Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.	ATP2A1 ATP2A2	1.73e-04	4	188	2	25110346
Pubmed	Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.	ATP2A1 ATP2A2	1.73e-04	4	188	2	10555147
Pubmed	Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle.	NFATC3 NFATC4	1.73e-04	4	188	2	17229811
Pubmed	Alternative splicing and expression of human and mouse NFAT genes.	NFATC3 NFATC4	1.73e-04	4	188	2	18675896
Pubmed	Transcription factors of the NFAT family: regulation and function.	NFATC3 NFATC4	1.73e-04	4	188	2	9143705
Pubmed	Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs).	ATP2A1 ATP2A2	1.73e-04	4	188	2	12032137
Pubmed	The nongastric H+-K+-ATPases: molecular and functional properties.	ATP2A1 ATP2A2	1.73e-04	4	188	2	10362770
Pubmed	Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle.	ATP2A1 ATP2A2	1.73e-04	4	188	2	12074580
Pubmed	G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression.	PHF20 EHMT2	1.73e-04	4	188	2	26960573
Pubmed	The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.	USP2 CCNA1	1.73e-04	4	188	2	22370483
Pubmed	Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.	NPY4R2 NPY4R	1.73e-04	4	188	2	7592911
Pubmed	SERCA1a can functionally substitute for SERCA2a in the heart.	ATP2A1 ATP2A2	1.73e-04	4	188	2	9887021
Pubmed	The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis.	NFATC3 NFATC4	1.73e-04	4	188	2	24970700
Pubmed	PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1.	APAF1 HSPA4	1.73e-04	4	188	2	18439902
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SLC37A1 ABCC4 ZBTB16 ACACA CEP192 TEP1 CDC42BPB ADCY1 SPTBN4 EXD3 LDB1 SYNJ2 CDYL2 NLRC5 MACF1 KATNIP RAI14 DAAM1 CLEC16A ICA1L	1.76e-04	1489	188	20	28611215
Pubmed	TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.	NFATC3 NFATC4 ATP2A2	1.92e-04	21	188	3	20194497
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC4 ABCC6 ABCB8	2.22e-04	22	188	3	8894702
Pubmed	Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.	YTHDC2 DMC1 SPATA22	2.22e-04	22	188	3	26742488
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO5 ACACA NSD1 YTHDC2 SBF1 ANAPC1 MACF1 KIF5B HERC2 ATP2A2 HSPA4 RPL10	2.47e-04	653	188	12	22586326
Pubmed	Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.	NFATC3 NFATC4	2.88e-04	5	188	2	17693409
Pubmed	Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.	NFATC3 NFATC4	2.88e-04	5	188	2	22593154
Pubmed	The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity.	APAF1 HSPA4	2.88e-04	5	188	2	31577950
Pubmed	Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.	NPY4R2 NPY4R	2.88e-04	5	188	2	7493937
Pubmed	The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.	ATP2A1 ATP2A2	2.88e-04	5	188	2	30299255
Pubmed	Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14.	NPY4R SFTPA1	2.88e-04	5	188	2	9441761
Pubmed	NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy.	NFATC3 NFATC4	2.88e-04	5	188	2	20530871
Pubmed	Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif.	NFATC3 NFATC4	2.88e-04	5	188	2	7999066
Pubmed	Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT.	NFATC3 NFATC4	2.88e-04	5	188	2	10089876
Pubmed	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68.	ODF2 CCDC120	2.88e-04	5	188	2	28422092
Pubmed	NFAT: ubiquitous regulator of cell differentiation and adaptation.	NFATC3 NFATC4	2.88e-04	5	188	2	11877454
Pubmed	p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.	APAF1 HSPA4	2.88e-04	5	188	2	15735003
Pubmed	TRAIP regulates replication fork recovery and progression via PCNA.	TRAIP RFC2 FANCD2	4.13e-04	27	188	3	27462463
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	ACACA CEP192 ODF2 ZZEF1 FBXO30 HERC2 TMCO1	4.14e-04	247	188	7	32989298
GeneFamily	NLR family	NLRP12 NLRP14 NLRC5 NLRC3	2.54e-05	25	126	4	666
GeneFamily	Nuclear factors of activated T-cells	NFATC3 NFATC4	4.75e-04	5	126	2	665
GeneFamily	Cyclins	CCNO CCNA1 CCNI	9.53e-04	28	126	3	473
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN4 SPTBN5	9.89e-04	7	126	2	1113
GeneFamily	Ankyrin repeat domain containing	IBTK TRANK1 EHMT2 RAI14 ANKFN1 ANKS3 ANKRD30BL	1.55e-03	242	126	7	403
GeneFamily	ATPases Ca2+ transporting	ATP2A1 ATP2A2	1.68e-03	9	126	2	1209
GeneFamily	Cyclins\|F-boxes other	FBXO30 FBXO10 FBXO39	2.51e-03	39	126	3	560
GeneFamily	ATP binding cassette subfamily C	ABCC4 ABCC6	3.57e-03	13	126	2	807
GeneFamily	Aquaporins	AQP12A AQP12B	4.15e-03	14	126	2	305
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZBTB16 FAT3 ADCY1 PREX2 ANGPTL4 SLIT3 ULK4 MACF1 FGFR4	1.34e-07	193	187	9	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM23 FAT3 STYK1 NWD2 SYNJ2 SLIT3 VPS13A NEUROD6	1.24e-06	186	187	8	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 GPR173 RFX8 PREX2 LHFPL2 TM4SF1 RPL10	1.64e-06	193	187	8	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 GPR173 RFX8 PREX2 LHFPL2 TM4SF1 RPL10	1.64e-06	193	187	8	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 CHGA VPS13A MACF1 KIF5B HERC1 ATP2A2 PCSK9	1.77e-06	195	187	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DND1 STK31 TRANK1 TLR5 ANKFN1 DNAH8 ATP4A	2.60e-06	144	187	7	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCC4 RPRML SYT10 FANCD2 SPTBN5 RAI14 NEUROD6	3.57e-06	151	187	7	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CCDC125 STON1 ZSCAN5A SAT1 PLIN5 CDYL2 CCDC120	5.44e-06	161	187	7	f5da03c426f3124ea302bd343b6bca81cafee858
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC125 STON1 ZSCAN5A SAT1 PLIN5 CDYL2 CCDC120	5.67e-06	162	187	7	4e3bf16799c6552366d4c7e42b1328a05dcad7e7
ToppCell	P15\|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZBTB16 TMEM204 PREX2 LYVE1 SAT1 TMEM252 TM4SF1	8.08e-06	171	187	7	155e7abd52b84d16146001f6ca49ca0c2294a823
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASNSD1 USP18 TMEM204 CEP192 LYVE1 FAM72A CLEC16A	9.05e-06	174	187	7	4a18b51501eaaeb7907e99316ba8ae15b2c7d529
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GLB1L2 RFX8 ACCSL NEUROD6 ANKFN1	9.91e-06	68	187	5	6945089858778301a05ecc5895310d768768758c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GLB1L2 RFX8 ACCSL NEUROD6 ANKFN1	9.91e-06	68	187	5	ac9d0f473c878b96a422bbdd7088eb8125574dde
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 PREX2 KCNJ15 CDYL2 LHFPL2 TM4SF1	1.26e-05	183	187	7	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 PREX2 KCNJ15 CDYL2 LHFPL2 TM4SF1	1.26e-05	183	187	7	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	FAM72D FAM72C FANCD2 NDC1 TBC1D31 FAM72A FAM72B	1.26e-05	183	187	7	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C TRAIP GLB1L2 ATAD3C ATP2A1 FAM72B	1.26e-05	183	187	7	f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell\|TCGA-Uvea / Sample_Type by Project: Shred V9	ARMC9 TEP1 ADCY1 FAM72A LHFPL2 ATP2A2 HSPA4	1.40e-05	186	187	7	e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCC4 ACACA SAT1 KCNJ15 TM4SF1 CLEC16A ANKRD30BL	1.40e-05	186	187	7	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 CDC42BPB PREX2 LHFPL2 TMEM252 ATP2A1 TM4SF1	1.44e-05	187	187	7	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 CDC42BPB PREX2 LHFPL2 TMEM252 ATP2A1 TM4SF1	1.44e-05	187	187	7	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 CDC42BPB PREX2 LHFPL2 TMEM252 ATP2A1 TM4SF1	1.44e-05	187	187	7	81754e965848b718be20ee97ce072ce426938a69
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	STON1 DCDC1 SPTBN4 BTBD16 NFATC4 RAI14	1.55e-05	126	187	6	10e1448a03f79965b72922fd83ef51de1b7b474f
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	MON2 USP18 USP38 ABCB8 NLRC5 HSPA4 NLRC3	1.60e-05	190	187	7	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ZBTB16 ACACA ARMC9 BTBD16 PLIN5 KCNJ15 SFTPA1	1.71e-05	192	187	7	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 RFX8 PREX2 KCNJ15 LHFPL2 TM4SF1	1.77e-05	193	187	7	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ABCC4 ACACA ARMC9 PLIN5 KCNJ15 SFTPA1 RAI14	1.77e-05	193	187	7	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 CHGA PREX2 LYVE1 MACF1 TM4SF1	1.77e-05	193	187	7	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHGA VPS13A MACF1 KIF5B HERC1 ATP2A2 PCSK9	1.89e-05	195	187	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	FAM72D FAM72C ODF2 FANCD2 TBC1D31 CCNA1 FAM72B	2.09e-05	198	187	7	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	distal-1-Endothelial-Vein\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZBTB16 TMEM204 ADAM23 LYVE1 CCL15 DAAM1 TM4SF1	2.09e-05	198	187	7	eee6cb4fe0e1caf460869d5a0a57c9d259573f10
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCNO RFX8 SYT10 TEKT2 IQCC CCNA1 IHH	2.16e-05	199	187	7	92778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	STON1 DND1 SYT10 ADCY1 AFAP1L2 DIXDC1 SLC44A3	2.16e-05	199	187	7	a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	STON1 DND1 SYT10 ADCY1 AFAP1L2 DIXDC1 SLC44A3	2.16e-05	199	187	7	8dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CALCR STYK1 DMC1 NLRC5 SPATA22	3.48e-05	88	187	5	2075743c7c0b6d74e80464a6bc776206d744d502
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CALCR STYK1 DMC1 NLRC5 SPATA22	3.48e-05	88	187	5	a49319bc97188550e08248973e10c626124c3917
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CALCR STYK1 DMC1 NLRC5 SPATA22	3.48e-05	88	187	5	14b11249a2b3fa327622897fe74630c2697ea47e
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNO SYT10 TEKT2 ADAM5 CCNA1 ANKFN1	4.30e-05	151	187	6	e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNO SYT10 TEKT2 ADAM5 CCNA1 ANKFN1	4.30e-05	151	187	6	633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCC4 RPRML SYT10 FANCD2 SPTBN5 RAI14	4.80e-05	154	187	6	12cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCC4 RPRML SYT10 FANCD2 SPTBN5 RAI14	5.16e-05	156	187	6	fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FBXL13 CCNO SYT10 TEKT2 CEP78 DIXDC1	5.34e-05	157	187	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	ADCY1 USP2 NWD2 VPS13A NEUROD6 RPL10	5.73e-05	159	187	6	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPRML SPTBN4 DMC1 USO1 DHX29 EDRF1	6.58e-05	163	187	6	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRAIP SYT10 FANCD2 SLIT3 NEUROD6 RPL10	7.77e-05	168	187	6	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	severe_COVID-19-Neutrophil\|World / disease group, cell group and cell class (v2)	HCAR2 LYVE1 SAT1 KCNJ15 FGFR4 RPL10	8.30e-05	170	187	6	dfc807e0dd66179490a258ecbe8eb439e715799d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 NWD2 SYNJ2 SLIT3 CDYL2 ICA1L	8.30e-05	170	187	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCC4 SYT10 FANCD2 SPTBN5 SLIT3 NEUROD6	8.57e-05	171	187	6	d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MROH2A CCNO BTBD16 TEKT2 IQCC CCNA1	8.57e-05	171	187	6	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZBTB16 CALCR PTGDR FBXO30 SYNJ2 SLC44A3	8.85e-05	172	187	6	a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell	severe_COVID-19-Neutrophil\|severe_COVID-19 / disease group, cell group and cell class (v2)	HCAR2 LYVE1 SAT1 KCNJ15 FGFR4 RPL10	8.85e-05	172	187	6	8f4bcb9b2bbf8b4333f673d8ad6bb88dfda4792a
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))-\|Thalamus / BrainAtlas - Mouse McCarroll V32	NLRP12 HAO1 LRIT3 NEUROD6	9.61e-05	57	187	4	ef44602342511a9f90c93463628ad8b154cb26fb
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))\|Thalamus / BrainAtlas - Mouse McCarroll V32	NLRP12 HAO1 LRIT3 NEUROD6	9.61e-05	57	187	4	a3dc14f7a63cc70b2789770644e0b9453426c6f9
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2F1 CTC1 BST1 ULK4 ATG4C SFTPA1	9.73e-05	175	187	6	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RPRML SYT10 FANCD2 SLIT3 NEUROD6 RPL10	1.00e-04	176	187	6	a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL10L CCNO SYT10 TEKT2 ADAM5 CCNA1	1.00e-04	176	187	6	d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL10L CCNO SYT10 TEKT2 ADAM5 CCNA1	1.00e-04	176	187	6	c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2F1 FAT3 CCNO SFTPA1 CCDC120 SLC44A3	1.04e-04	177	187	6	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2F1 FAT3 CCNO SFTPA1 CCDC120 SLC44A3	1.04e-04	177	187	6	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	APAF1 CEP192 CDC42BPB FANCD2 TXNDC16	1.05e-04	111	187	5	dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FANCD2 LYVE1 BST1 RAI14 TMEM252 TM4SF1	1.07e-04	178	187	6	ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA CYP2F1 GPR173 DPH5 MACF1 DIXDC1	1.07e-04	178	187	6	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FANCD2 LYVE1 BST1 RAI14 TMEM252 TM4SF1	1.07e-04	178	187	6	ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FANCD2 LYVE1 BST1 RAI14 TMEM252 TM4SF1	1.07e-04	178	187	6	87b04753650e45f12299c8456fb980d6c0d5961c
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPRML GPR173 CHGA ADCY1 TEKT2 ATAD3C	1.10e-04	179	187	6	f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CALCR RPRML ITPRID2 CHGA SPTBN4 GUCY2C	1.10e-04	179	187	6	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PHF20 C15orf39 AFAP1L2 VPS13A ATG4C CLEC16A	1.10e-04	179	187	6	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CALCR RPRML GPR173 ITPRID2 CHGA SPTBN4	1.10e-04	179	187	6	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 CHGA PREX2 LHFPL2 MACF1	1.14e-04	180	187	6	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ADAM23 CHGA PREX2 LHFPL2 MACF1	1.14e-04	180	187	6	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	(05)_Ciliated-(3)_72hpi\|(05)_Ciliated / shred by cell type and Timepoint	CCNO TBC1D31 ADAM5 CCNA1 DNAH8	1.15e-04	113	187	5	eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC4 TMEM204 ADAM23 APAF1 LHFPL2 TM4SF1	1.17e-04	181	187	6	4df7972f88117108698efd06b124b232f8588981
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID2 PREX2 LYVE1 AFAP1L2 SAT1 TM4SF1	1.17e-04	181	187	6	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC4 TMEM204 ADAM23 APAF1 LHFPL2 TM4SF1	1.17e-04	181	187	6	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 ADAM23 KCNJ15 LHFPL2 TM4SF1	1.21e-04	182	187	6	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 ADAM23 KCNJ15 LHFPL2 TM4SF1	1.21e-04	182	187	6	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITPRID2 PREX2 LYVE1 AFAP1L2 SAT1 TM4SF1	1.24e-04	183	187	6	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	ACACA ABCC6 NWD2 SAT1 PLIN5 ANGPTL4	1.24e-04	183	187	6	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	facs-Skin-Telogen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ABCC4 CS SAT1 ACSBG1 HSPA4	1.24e-04	183	187	6	26b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IPO5 DCDC1 NWD2 SYNJ2 SLIT3 ATP4A	1.24e-04	183	187	6	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IPO5 DCDC1 STYK1 NWD2 SYNJ2 SLIT3	1.28e-04	184	187	6	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 USP2 TEKT2 CES4A CCL15 ANKFN1	1.32e-04	185	187	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PREX2 TEKT2 SYNJ2 CCDC120 TM4SF1	1.32e-04	185	187	6	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	COVID-19_Moderate-NK_activated\|World / disease group, cell group and cell class	USP18 PTGDR TRANK1 CEP78 FBXO39 NLRC3	1.36e-04	186	187	6	ff8f32f69516bf785224fa12f8139a95359b0279
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.36e-04	186	187	6	73cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D RFC2 NLRP14 FAM72A ATP2A1 FAM72B	1.36e-04	186	187	6	86d145f965c311189e7996390eef491642417c5c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PREX2 ACSBG1 NFATC4 PLIN5 KCNJ10 ANGPTL4	1.40e-04	187	187	6	93c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 PREX2 AFAP1L2 SLIT3 TM4SF1	1.44e-04	188	187	6	da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 ADAM23 PREX2 LHFPL2 TM4SF1	1.44e-04	188	187	6	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ABCC4 ACACA ARMC9 PLIN5 KCNJ15 SFTPA1	1.44e-04	188	187	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 PREX2 AFAP1L2 SLIT3 TM4SF1	1.44e-04	188	187	6	b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 TMEM204 PREX2 AFAP1L2 SLIT3 TM4SF1	1.44e-04	188	187	6	19672d284fe89c9c3c7697514ca1f659329c34f4
ToppCell	COVID-19_Severe-Myeloid_G-Neutrophil\|COVID-19_Severe / Disease group, lineage and cell class	HCAR2 FBXL18 SAT1 PLIN5 KCNJ15 TLR5	1.48e-04	189	187	6	a62f4c445ede00d15b74bee65f4e4fb54cfd4d32
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	HCAR2 FBXL18 SAT1 PLIN5 KCNJ15 TLR5	1.48e-04	189	187	6	db8e314ce95c32542bb4015a77032a33211fea0b
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM204 ZZEF1 CDC42BPB SDHAF2 CDYL2 NLRC5	1.48e-04	189	187	6	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
Disease	Brody myopathy (implicated_via_orthology)	ATP2A1 ATP2A2	1.08e-04	3	178	2	DOID:0050692 (implicated_via_orthology)
Disease	T-cell acute lymphoblastic leukemia (implicated_via_orthology)	RPL10L RPL10	1.08e-04	3	178	2	DOID:5603 (implicated_via_orthology)
Disease	fibroblast growth factor 23 measurement	ASNSD1 NSD1 FGFR4 PCSK9	1.31e-04	43	178	4	EFO_0009381
Disease	autistic disorder (implicated_via_orthology)	RPL10L RPL10	2.15e-04	4	178	2	DOID:12849 (implicated_via_orthology)
Disease	p53 and DNA damage-regulated protein 1 measurement	ASNSD1 NLRP12	2.15e-04	4	178	2	EFO_0803313
Disease	double-stranded RNA-binding protein Staufen homolog 1 measurement	NLRP12 BET1L	3.58e-04	5	178	2	EFO_0801546
Disease	y-box-binding protein 2 measurement	NLRP12 BET1L	3.58e-04	5	178	2	EFO_0802224
Disease	60S ribosomal protein L30 measurement	NLRP12 BET1L	3.58e-04	5	178	2	EFO_0801337
Disease	40S ribosomal protein S3a measurement	NLRP12 BET1L	3.58e-04	5	178	2	EFO_0801333
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	5.34e-04	6	178	2	EFO_0004307, EFO_0008463
Disease	40s ribosomal protein S3 measurement	NLRP12 BET1L	5.34e-04	6	178	2	EFO_0020117
Disease	40s ribosomal protein S7 measurement	NLRP12 BET1L	5.34e-04	6	178	2	EFO_0020118
Disease	spondyloepiphyseal dysplasia congenita (implicated_via_orthology)	RPL10L RPL10	5.34e-04	6	178	2	DOID:14789 (implicated_via_orthology)
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	HCAR2 TRAIP ANGPTL4 NLRC5 MACF1 ATP4A PCSK9	7.13e-04	243	178	7	EFO_0004612, EFO_0020944
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	RPL10L RPL10	7.45e-04	7	178	2	DOID:0060807 (implicated_via_orthology)
Disease	aortic measurement	RPL10L DCDC1 RPRML SYT10 SPTBN4 ULK4 HSPA4	8.62e-04	251	178	7	EFO_0020865
Disease	40S ribosomal protein S4, X isoform measurement	NLRP12 BET1L	9.89e-04	8	178	2	EFO_0801334
Disease	waist-hip ratio	HCAR2 CALCR ADAM23 TRAIP NSD1 YTHDC2 CEP192 ZZEF1 SCN4A KCNJ15 CDADC1 CDYL2 DIXDC1 FGFR4 ATP2A1 CLEC16A HSPA4	1.26e-03	1226	178	17	EFO_0004343
Disease	Manic	TRANK1 DIXDC1 DNAH8 HSPA4	1.29e-03	78	178	4	C0338831
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	HCAR2 TRAIP ANGPTL4 NLRC5 MACF1 ATP4A PCSK9	1.49e-03	276	178	7	EFO_0004612, EFO_0020943
Disease	complement C1q tumor necrosis factor-related protein 5 measurement	APAF1 USP2	1.92e-03	11	178	2	EFO_0801494
Disease	apolipoprotein A 1 measurement	STON1 TRAIP NSD1 TRANK1 NFATC3 ANGPTL4 NLRC5 MACF1 ATG4C FGFR4 HERC1 PCSK9 OR5D13	2.00e-03	848	178	13	EFO_0004614
Disease	chronic musculoskeletal pain	EXD3 GMPPB	2.30e-03	12	178	2	EFO_0022195
Disease	alpha-hydroxybutyric acid measurement	ABCC4 SYT10	2.30e-03	12	178	2	EFO_0010458
Disease	amino acid measurement	IPO5 ABCC4 DCDC1 STYK1 SYT10 GUCY2C SCN4A ABCB8 SLIT3 TXNDC16 ULK4	2.85e-03	678	178	11	EFO_0005134
Disease	sexual dimorphism measurement	PHF20 NSD1 ZZEF1 SPTBN5 TRANK1 NFATC4 ANGPTL4 SCN4A SLIT3 NLRC5 ULK4 MACF1 FGFR4 HERC1 ANKS3	2.99e-03	1106	178	15	EFO_0021796
Disease	femoral neck bone geometry	NSD1 FGFR4	3.14e-03	14	178	2	EFO_0004511
Disease	cholesteryl esters to total lipids in IDL percentage	ANGPTL4 MACF1 PCSK9	3.44e-03	50	178	3	EFO_0022247
Disease	diffuse idiopathic skeletal hyperostosis	HAO1 ANKFN1	3.61e-03	15	178	2	EFO_0007236
Disease	Colorectal Carcinoma	ABCC4 ACACA ZSCAN5A ABCC6 PREX2 FBXO30 LDB1 GUCY2C VPS13A DNAH8 EDRF1	3.71e-03	702	178	11	C0009402
Disease	Liver carcinoma	ACACA TRAIP FANCD2 USP2 LYVE1 FBXL18 CCNA1 NLRC3 FAM72B	3.81e-03	507	178	9	C2239176
Disease	interleukin 1 receptor antagonist measurement	NLRP12 TRANK1 ATG4C	4.05e-03	53	178	3	EFO_0004754
Disease	5-oxoproline measurement	CCNI DNAH8	4.11e-03	16	178	2	EFO_0010988
Disease	Congestive heart failure	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C0018802
Disease	Heart failure	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C0018801
Disease	Left-Sided Heart Failure	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C0023212
Disease	Heart Failure, Right-Sided	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C0235527
Disease	Heart Decompensation	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C1961112
Disease	Myocardial Failure	ACACA CS ATP2A1 ATP2A2	4.50e-03	110	178	4	C1959583
Disease	cholesteryl esters to total lipids in medium HDL percentage	NFATC3 ANGPTL4 NLRC5	4.73e-03	56	178	3	EFO_0022251
Disease	syndrome (implicated_via_orthology)	NSD1 ATAD3C	5.20e-03	18	178	2	DOID:225 (implicated_via_orthology)
Disease	lymphocyte measurement	NLRP12 NFATC3 ANAPC1 NLRC5	5.59e-03	117	178	4	EFO_0803546
Disease	cholesterol to total lipids in IDL percentage	ANGPTL4 MACF1 PCSK9	5.74e-03	60	178	3	EFO_0022233

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSRLICRMINLLQSG	ACCSL	71	Q4AC99
CRMINLLQSGAASGL	ACCSL	76	Q4AC99
GNILGTTMERKLCSQ	C2orf16	896	Q68DN1
DKSGLLMKLQNLCTR	APAF1	191	O14727
SLMKSLAQGGRTIIC	ABCG4	241	Q9H172
MAAQGCAASRLLQLL	BST1	1	Q10588
LSVCSGLRGTMQLKN	ADAM5	76	Q6NVV9
LDRKCLQIQALNMSS	ADAM23	721	O75077
LMLCAATAVLLSAQG	ANGPTL4	11	Q9BY76
LKLAAQGLGMQAACT	AQP12A	101	Q8IXF9
NTGAMRRCVKLTVAL	CTC1	921	Q2NKJ3
CMGKLQLLVAINSTS	CCNO	316	P22674
GDLLSLSQMCKALSI	BTBD16	31	Q32M84
LGCQRVTLHKNMFLT	CALCR	176	P30988
MLACLTRGNLLDVLQ	DIXDC1	1	Q155Q3
MALANSVQGCLIRKC	FBXO10	421	Q9UK96
CLARGSMIVLQNLTL	FGFR4	101	P22455
TMARSGQDNRKLLCG	BET1L	76	Q9NYM9
KCSAGLKLSNLMNLG	AFAP1L2	326	Q8N4X5
LMKLSTRLCGDNNRI	AP1G2	531	O75843
CNQLLQFRGSMLALA	CCNI	191	Q14094
IRLKNTCTIDGFLML	C14orf28	51	Q4W4Y0
VLIANNGIAAVKCMR	ACACA	121	Q13085
LSGCNAAILKRETMR	EHMT2	456	Q96KQ7
AALSCLMLVAVLGSQ	CCL15	6	Q16663
MAGLRRITLNCNTLI	CEP78	226	Q5JTW2
ACLKMIVNAGVNRIS	CDADC1	136	Q9BWV3
LKLAAQGLGMQAACT	AQP12B	101	A6NM10
IQMTTRRALCNVKGL	DMC1	51	Q14565
ISNAMNLLRKIGACE	DHX29	1046	Q7Z478
TTCLALGTRRMAKKN	ATP2A1	316	O14983
CTLRTGQMLLAQGLI	ATG4C	111	Q96DT6
SIRRMIGQKLNNCTK	BEND6	251	Q5SZJ8
TRMKLLENCLKTSAG	NWD2	101	Q9ULI1
RNKSGRTALMLACEI	RAI14	181	Q9P0K7
VLATVLCNLGAMRNL	PTGDR	211	Q13258
MLSLSKKALAGTCQR	NSD1	2261	Q96L73
GNLCMILLIRTNSQL	OR5M10	41	Q6IEU7
GNLLLLCSQDMLTSL	CYP2F1	41	P24903
LRKISNAQRMGCVLI	GUCY2C	106	P25092
RQTFGGTCLLQMKIL	IQCC	306	Q4KMZ1
VAMSQRLCALLVAGS	OR5D14	136	Q8NGL3
KMTRILQDSLGGNCR	KIF5B	281	P33176
VMAGSGNLKVLQLCR	ANAPC1	1526	Q9H1A4
KNRQNGMHTLCLLDI	DPH5	151	Q9H2P9
KIAAGTLRQMCTVDL	DPH5	231	Q9H2P9
KTGMILSRAITQGCL	DCDC1	706	M0R2J8
CRIMGITLVSKKANQ	LYVE1	36	Q9Y5Y7
VMDATQIAGLNCLRL	HSPA4	156	P34932
QIAGLNCLRLMNETT	HSPA4	161	P34932
ANMRKSLLIGCQVTG	KCNJ10	201	P78508
QMLDQLSKNITRCGL	LDB1	221	Q86U70
LMGALCTNQTLLSLS	NLRC3	826	Q7RTR2
VLGNLCLMCVTVRQK	NPY4R	56	P50391
CKQVLSSRGMKAVLL	FAM72D	21	Q6L9T8
QLACAKLISRTGLLM	LRRC37A5P	61	Q49AS3
QALDLLMAEKGRTCL	ERVFC1-1	481	P60608
ATNAALLLCNTGRLM	EDRF1	896	Q3B7T1
STLINRCLQRKMTGE	HCAR2	306	Q8TDS4
QSEATKTLCGLLRML	HERC2	1986	O95714
LKLSCLQFIGLNMAA	IBTK	891	Q9P2D0
SLIQQLENLMGRKIC	KATNIP	731	O60303
ALLMNLCLRSTGKNM	ARMC9	481	Q7Z3E5
TNIKMGAIRVANCNL	KIAA1109	1011	Q2LD37
LTGMCLFLQSLRQKQ	GMPPB	226	Q9Y5P6
KLQLLMATGCQSGLV	HERC1	3686	Q15751
TTQGVCLGMRLAQLS	CCDC120	191	Q96HB5
VNRKGLHSLNCLMVC	HARBI1	166	Q96MB7
VAKGASMRSLRVLNC	PCSK9	241	Q8NBP7
SMRSLRVLNCQGKGT	PCSK9	246	Q8NBP7
LCRQAVLNMILTGRA	MINDY4B	296	A8MYZ0
LVNCLRALSGTKVMR	CES4A	281	Q5XG92
CRKKMQAASTLIDGL	DNAH8	3346	Q96JB1
TMRGLLSCLSKSNNR	FBXO39	111	Q8N4B4
RLAMALSGCQNVKVI	HAO1	341	Q9UJM8
GKLCLVIQVANMRKS	KCNJ15	191	Q99712
NMRKSLLIQCQLSGK	KCNJ15	201	Q99712
FCMLLQNALKGIQSL	HEATR6	231	Q6AI08
RQMLCITVLLGLNDS	HEATR6	811	Q6AI08
NLEAKVTMLISGRCQ	LCN1	66	P31025
SIMKKSIFNVCGLLQ	LHFPL2	126	Q6ZUX7
DLGMKILSSLCNRLR	GBP7	616	Q8N8V2
TKIMSALGSNVLLRC	LRIT3	261	Q3SXY7
CKQVLSSRGMKAVLL	FAM72A	21	Q5TYM5
KITQLCLAAIQRLMS	MON2	81	Q7Z3U7
KGCQLMATATLKRNS	CDC42BPB	1326	Q9Y5S2
LSLKLCGDTSLNNMQ	IPO5	261	O00410
TANRLMKTLSKLNLC	ITPRID2	291	P28290
KVCSLSNQRMGRSLL	ITPRID2	701	P28290
GQLMETCARLQQLSL	NLRC5	1456	Q86WI3
KCTRLGSHLNMLLGQ	MACF1	3986	Q9UPN3
GLQLRSCTFQLLKMA	SBF1	981	O95248
GRQLGAILKSCNMQA	MCAT	351	Q8IVS2
EISKILRSSCLRGMN	ABCC4	306	O15439
RIHTSLIGCIKALMN	DAAM1	176	Q9Y4D1
LIGCIKALMNNSQGR	DAAM1	181	Q9Y4D1
AVKVLASGCLQNMLL	GASK1A	511	Q9UFP1
EKRASTCGLMLLLAA	SLC37A1	391	P57057
NGSQIRSLGLDRKMC	ADCY1	1061	Q08828
TTCLALGTRRMAKKN	ATP2A2	316	P16615
CARMAASTRKLLLQL	CCDC125	291	Q86Z20
NCIGMRFALTNIKLA	CYP3A43	441	Q9HB55
MALLTAAARLLGTKN	CS	1	O75390
CKQVLSSRGMKAVLL	FAM72C	21	H0Y354
LSCMSVLRGKLQLVG	CCNA1	276	P78396
NLCMKAVNQSIGRAI	DDX11L8	836	A8MPP1
NIMRISAILEKNCSG	FAT3	3731	Q8TDW7
GDQRKFLSMLLTLKC	ACSBG1	601	Q96GR2
LTEGMSCRKIAQLAV	ATAD3C	346	Q5T2N8
LNLANCVRIGDMGLK	FBXL13	456	Q8NEE6
LIMCVSLAGNAILSL	GPR173	31	Q9NS66
MGQALCLVTQSLEKL	ANKS3	631	Q6ZW76
SDKCGRLQIMSLENL	ASNSD1	621	Q9NWL6
CMLARLEIKQLGNRS	CEP192	1851	Q8TEP8
RATLQLLCQRMKLGS	DND1	256	Q8IYX4
CDLLLARFGLIQSMK	IST1	76	P53990
CNLEVKGTQLNRMAL	SLC44A3	101	Q8N4M1
KGTQLNRMALCVSNC	SLC44A3	106	Q8N4M1
RLLKMKACGLNTLTT	GLB1L2	81	Q8IW92
KLMRDVCGSLLQSRG	FBXO30	641	Q8TB52
CQKVDLLGASRCNML	ICA1L	206	Q8NDH6
CMILSGQAADNLRAK	SLC17A5	341	Q9NRA2
VKFARQLAGGLQCLM	ATP4A	101	P20648
RCKDRLNSLAISVMN	IHH	106	Q14623
CKQVLSSRGMKAVLL	FAM72B	21	Q86X60
LLVCRVKAMLTLNNC	FANCD2	1366	Q9BXW9
VLMNRKKCLLLAAGA	OR2T11	131	Q8NH01
TIMSQKLCALLVAGS	OR5D13	136	Q8NGL4
SRLCMQIKNLERSGN	ODF2	361	Q5BJF6
LLMDLGKVQQIALCC	PHF20	996	Q9BVI0
KRGMLENCILLSLFA	SDHAF2	76	Q9NX18
LMGSGLRKLSRQCQE	ABCB8	311	Q9NUT2
IMGKRACIQLASGSL	OR10J3	136	Q5JRS4
SLIQKLCENTGAMNL	MROH2A	1081	A6NES4
KELSRCLVKGSLGMN	MS4A12	151	Q9NXJ0
VIRINKMLSCAGADR	RPL10L	96	Q96L21
LTCKSQRLMLQVGLI	PARS2	66	Q7L3T8
SKIQTRVGLLMLLCT	USO1	486	O60763
INMQTCKLLFEIGSL	TBC1D31	291	Q96DN5
FLGCNLLIKSESMIN	RPRML	86	Q8N4K4
LVGLQLFMGNLRQKC	SCN4A	266	P35499
CTMSIRQNIQKILGL	TMCO1	201	Q9UM00
CTMRGLDKNSALQTL	SPATA22	186	Q8NHS9
RFQKGTLRMNCLDCL	SYNJ2	376	O15056
RLAMLTLEGNLVCLQ	LRRC56	186	Q8IYG6
NMAANIDCAGILKLR	NFATC4	516	Q14934
LQRKGALMCLLDQAR	ABCC6	841	O95255
VIRINKMLSCAGADR	RPL10	96	P27635
QCQQLRSLSLANLGM	FBXL18	556	Q96ME1
CLKRLKNMNLEGSIQ	NEPRO	91	Q6NW34
MSGTLEKVLCLRNNT	MRPL48	1	Q96GC5
ARLQADIACKANSML	TEKT2	371	Q9UIF3
GSEILKNLSQVAMRC	SAT1	106	P21673
LALNLILMAASGAVC	SFTPA1	6	Q8IWL2
QSALGRCQAMLLRKE	SPTBN5	2651	Q9NRC6
LDGENRTILMKALQC	ANKRD30BL	101	A7E2S9
NLQTLRCTITGLTMG	ANKFN1	326	Q8N957
LANEMLFCGRKLTAQ	CDYL2	406	Q8N8U2
MRSAAVLALLLCAGQ	CHGA	1	P10645
CLLLKQQVLMSAGCI	CLEC16A	566	Q2KHT3
GCTSRMLKLLALRQL	C15orf39	891	Q6ZRI6
GLKTLMLRSNLIGCV	SLIT3	606	O75094
NILMQSDLTAKLCGL	STYK1	256	Q6J9G0
SINRNKDIMKIGCSL	STK31	51	Q9BXU1
LKGTSTMLLTRINCA	TXNDC16	436	Q9P2K2
LNITLSKCGLVMLNN	VPS13A	1841	Q96RL7
LCKANQMRLAGTLCD	ZBTB16	21	Q05516
MLRNLCNLLRVGISS	TEP1	526	Q99973
KMNRRACLGSLQELE	STON1	596	Q9Y6Q2
MKCLRNLISLLGTST	RFX8	351	Q6ZV50
ACNIMLLGAQRKTLS	PRPF31	246	Q8WWY3
CNLCGKRFMQLISLQ	ZSCAN5A	386	Q9BUG6
MSASIDCAGILKLRN	NFATC3	531	Q12968
VLGNLCLMCVTVRQK	NPY4R2	56	P0DQD5
CQELGRSLLLNKSAM	SPTBN4	2001	Q9H254
LLNCMLLGGRKNTDV	PREX2	146	Q70Z35
VNSLLQMAGLLARLC	RFC2	331	P35250
MQNRTGLILCALALL	TMEM252	1	Q8N6L7
TAGRMTLTVIKCRNL	SYT10	376	Q6XYQ8
RQVLSLNLNGCNSLM	USP38	471	Q8NB14
KRCAMLSSVLAALIG	TM4SF1	86	P30408
MFLTVKLLLGQRCSL	UBL4B	1	Q8N7F7
VLPTQASQKRAAMLC	YTHDC2	871	Q9H6S0
LLCCKMALLTQTQGS	ZKSCAN4	151	Q969J2
MQLTVKALQGRECSL	UBL4A	1	P11441
RLASQCMALKSVRQL	ZZEF1	1216	O43149
LNIGACLLATLAAAM	TMEM204	171	Q9BSN7
MSKAFGLLRQICQSI	USP18	1	Q9UMW8
LATMNSLACRGLDKL	PLIN5	86	Q00G26
CLVQSKMNLVAINGL	TRANK1	2176	O15050
QGRCLSDLNSALIMV	TLR5	776	O60602
MLARTRKELCTLQGL	USP2	171	O75604
LCRLMALRISGSQTK	WDR87	1246	Q6ZQQ6
EKSMGASRAKLNLLC	ULK4	476	Q96C45
LQQALGKAEMLCSTL	TRAIP	121	Q9BWF2
LQMIQLRKCQLESGA	NLRP12	801	P59046
LSSALICNKRLIKMN	NLRP14	1006	Q86W24
RVVCDNMLQGLARSL	EXD3	631	Q8N9H8
SRECLNLLNGMTQKL	NDC1	366	Q9BTX1
LVAGCLQLNARSFLM	NEUROD6	176	Q96NK8