Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	zinc ion binding	PAPPA2 SETMAR ZCWPW1 RNF5 MID2 ADAMTS1 ADAMTS9 TRIM35 NFXL1 AIRE ZFYVE1 TRIM59 KNG1	9.58e-05	891	85	13	GO:0008270
GeneOntologyCellularComponent	extracellular matrix	ADAMTS10 HSPG2 SOST FBN2 ADAMTS1 ADAMTS9 OTOGL PAPLN LAMC2 SERPINC1 MUC5B CTSB MUC5AC PLXNA2 KNG1 CDON	6.49e-09	656	84	16	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS10 HSPG2 SOST FBN2 ADAMTS1 ADAMTS9 OTOGL PAPLN LAMC2 SERPINC1 MUC5B CTSB MUC5AC PLXNA2 KNG1 CDON	6.78e-09	658	84	16	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS10 HSPG2 SOST FBN2 ADAMTS1 ADAMTS9 PAPLN LAMC2 SERPINC1 CTSB PLXNA2 KNG1 CDON	1.87e-07	530	84	13	GO:0062023
Domain	TSP_1	ADAMTS10 CILP2 SEMA5B ADAMTS1 ADAMTS9 PAPLN	3.56e-07	63	83	6	PF00090
Domain	TSP1	ADAMTS10 CILP2 SEMA5B ADAMTS1 ADAMTS9 PAPLN	4.30e-07	65	83	6	SM00209
Domain	TSP1_rpt	ADAMTS10 CILP2 SEMA5B ADAMTS1 ADAMTS9 PAPLN	4.30e-07	65	83	6	IPR000884
Domain	TSP1	ADAMTS10 CILP2 SEMA5B ADAMTS1 ADAMTS9 PAPLN	4.30e-07	65	83	6	PS50092
Domain	WxxW_domain	CILP2 MUC5B MUC5AC	1.68e-06	6	83	3	IPR025155
Domain	Mucin2_WxxW	CILP2 MUC5B MUC5AC	1.68e-06	6	83	3	PF13330
Domain	ADAM_spacer1	ADAMTS10 ADAMTS1 ADAMTS9 PAPLN	3.01e-06	23	83	4	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS1 ADAMTS9 PAPLN	3.01e-06	23	83	4	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTS1 ADAMTS9 PAPLN	3.60e-06	24	83	4	IPR013273
Domain	Cadherin_2	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.03e-05	65	83	5	PF08266
Domain	Cadherin_N	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.03e-05	65	83	5	IPR013164
Domain	Cadherin_tail	PCDHA9 PCDHA10 PCDHA5 PCDHA4	2.14e-05	37	83	4	PF15974
Domain	Cadherin_CBD	PCDHA9 PCDHA10 PCDHA5 PCDHA4	2.14e-05	37	83	4	IPR031904
Domain	CTCK_1	SOST MUC5B MUC5AC	6.58e-05	18	83	3	PS01185
Domain	CT	SOST MUC5B MUC5AC	1.23e-04	22	83	3	SM00041
Domain	Cadherin_CS	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.25e-04	109	83	5	IPR020894
Domain	CADHERIN_1	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.48e-04	113	83	5	PS00232
Domain	Cadherin	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.48e-04	113	83	5	PF00028
Domain	CADHERIN_2	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.54e-04	114	83	5	PS50268
Domain	-	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.54e-04	114	83	5	2.60.40.60
Domain	CA	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.61e-04	115	83	5	SM00112
Domain	Cadherin-like	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.67e-04	116	83	5	IPR015919
Domain	Cadherin	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.81e-04	118	83	5	IPR002126
Domain	Cys_knot_C	SOST MUC5B MUC5AC	1.81e-04	25	83	3	IPR006207
Domain	CTCK_2	SOST MUC5B MUC5AC	1.81e-04	25	83	3	PS01225
Domain	MetalloPept_cat_dom	ADAMTS10 PAPPA2 ADAMTS1 ADAMTS9	4.65e-04	81	83	4	IPR024079
Domain	-	ADAMTS10 PAPPA2 ADAMTS1 ADAMTS9	4.65e-04	81	83	4	3.40.390.10
Domain	Man6P_isomerase_rcpt-bd_dom	ELAPOR2 IGF2R	5.37e-04	8	83	2	IPR009011
Domain	LAMININ_IVA	HSPG2 LAMC2	5.37e-04	8	83	2	PS51115
Domain	Laminin_B	HSPG2 LAMC2	5.37e-04	8	83	2	PF00052
Domain	LamB	HSPG2 LAMC2	5.37e-04	8	83	2	SM00281
Domain	Laminin_IV	HSPG2 LAMC2	5.37e-04	8	83	2	IPR000034
Domain	EGF	HSPG2 FBN2 TENM3 LAMC2 DLK1 LRP1B	6.27e-04	235	83	6	SM00181
Domain	Growth_fac_rcpt_	HSPG2 ELAPOR2 FBN2 LAMC2 LRP1B	6.55e-04	156	83	5	IPR009030
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS1 ADAMTS9	6.89e-04	39	83	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS1 ADAMTS9	6.89e-04	39	83	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS1 ADAMTS9	7.43e-04	40	83	3	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS1 ADAMTS9	7.43e-04	40	83	3	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS1 ADAMTS9	7.43e-04	40	83	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS1 ADAMTS9	7.43e-04	40	83	3	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS1 ADAMTS9	7.43e-04	40	83	3	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS1 ADAMTS9	7.99e-04	41	83	3	IPR001762
Domain	Znf_RING_CS	RNF5 MID2 TRIM35 MKRN2 TRIM59	7.99e-04	163	83	5	IPR017907
Domain	EGF-like_dom	HSPG2 FBN2 TENM3 LAMC2 DLK1 LRP1B	8.47e-04	249	83	6	IPR000742
Domain	-	RNF5 MID2 TRIM35 MKRN2 AIRE KAT6B ZFYVE1 TRIM59	8.55e-04	449	83	8	3.30.40.10
Domain	ZINC_PROTEASE	ADAMTS10 PAPPA2 ADAMTS1 ADAMTS9	9.54e-04	98	83	4	PS00142
Domain	EGF_1	HSPG2 FBN2 TENM3 LAMC2 DLK1 LRP1B	9.58e-04	255	83	6	PS00022
Domain	Znf_RING/FYVE/PHD	RNF5 MID2 TRIM35 MKRN2 AIRE KAT6B ZFYVE1 TRIM59	9.86e-04	459	83	8	IPR013083
Domain	Znf_C3HC4_RING-type	RNF5 MID2 TRIM35 MKRN2 TRIM59	1.02e-03	172	83	5	IPR018957
Domain	EGF-like_CS	HSPG2 FBN2 TENM3 LAMC2 DLK1 LRP1B	1.08e-03	261	83	6	IPR013032
Domain	EGF_2	HSPG2 FBN2 TENM3 LAMC2 DLK1 LRP1B	1.17e-03	265	83	6	PS01186
Domain	TIL	MUC5B MUC5AC	1.25e-03	12	83	2	PF01826
Domain	C8	MUC5B MUC5AC	1.25e-03	12	83	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC5B MUC5AC	1.47e-03	13	83	2	IPR014853
Domain	C8	MUC5B MUC5AC	1.47e-03	13	83	2	SM00832
Domain	IRS_PTB	DOK4 TLN2	1.72e-03	14	83	2	IPR002404
Domain	PLAC	ADAMTS10 PAPLN	1.72e-03	14	83	2	PF08686
Domain	TIL_dom	MUC5B MUC5AC	1.72e-03	14	83	2	IPR002919
Domain	IRS	DOK4 TLN2	1.72e-03	14	83	2	PF02174
Domain	ZF_RING_1	RNF5 MID2 TRIM35 MKRN2 NFXL1 TRIM59	1.88e-03	291	83	6	PS00518
Domain	Glyco_hormone_CN	MUC5B MUC5AC	1.97e-03	15	83	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	1.97e-03	15	83	2	PF00007
Domain	ZF_RING_2	RNF5 MID2 TRIM35 MKRN2 NFXL1 TRIM59	2.12e-03	298	83	6	PS50089
Domain	EGF_CA	HSPG2 FBN2 DLK1 LRP1B	2.14e-03	122	83	4	SM00179
Domain	VWD	MUC5B MUC5AC	2.25e-03	16	83	2	SM00216
Domain	VWF_type-D	MUC5B MUC5AC	2.25e-03	16	83	2	IPR001846
Domain	VWFD	MUC5B MUC5AC	2.25e-03	16	83	2	PS51233
Domain	VWD	MUC5B MUC5AC	2.25e-03	16	83	2	PF00094
Domain	EGF-like_Ca-bd_dom	HSPG2 FBN2 DLK1 LRP1B	2.27e-03	124	83	4	IPR001881
Domain	EGF_extracell	TENM3 DLK1 LRP1B	2.41e-03	60	83	3	IPR013111
Domain	EGF_2	TENM3 DLK1 LRP1B	2.41e-03	60	83	3	PF07974
Domain	CarboxyPept-like_regulatory	CILP2 TENM3	2.54e-03	17	83	2	IPR008969
Domain	ConA-like_dom	PAPPA2 HSPG2 MID2 TRIM35 ADGRD1	2.93e-03	219	83	5	IPR013320
Domain	zf-C3HC4	RNF5 MID2 TRIM35 MKRN2 TRIM59	3.17e-03	223	83	5	PF00097
Domain	VWC_out	MUC5B MUC5AC	3.18e-03	19	83	2	SM00215
Domain	PLAC	ADAMTS10 PAPLN	3.18e-03	19	83	2	PS50900
Domain	PLAC	ADAMTS10 PAPLN	3.18e-03	19	83	2	IPR010909
Domain	Znf_RING	RNF5 MID2 TRIM35 MKRN2 NFXL1 TRIM59	3.30e-03	326	83	6	IPR001841
Domain	PWWP	ZCWPW1 DNMT3A	3.52e-03	20	83	2	SM00293
Domain	-	MID2 TRIM35 TRIM59	3.89e-03	71	83	3	4.10.45.10
Domain	EGF_3	HSPG2 FBN2 TENM3 DLK1 LRP1B	3.96e-03	235	83	5	PS50026
Domain	zf-B_box	MID2 TRIM35 TRIM59	4.05e-03	72	83	3	PF00643
Domain	Znf_FYVE_PHD	AIRE KAT6B ZFYVE1 DNMT3A	4.18e-03	147	83	4	IPR011011
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 SEMA5B ADAMTS1 ADAMTS9 MUC5B MUC5AC	4.53e-07	68	61	6	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 HSPG2 SEMA5B ADAMTS1 ADAMTS9 MUC5B MUC5AC	2.63e-06	143	61	7	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 SEMA5B ADAMTS1 ADAMTS9 MUC5B MUC5AC	7.31e-06	109	61	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 SEMA5B ADAMTS1 ADAMTS9 MUC5B MUC5AC	8.12e-06	111	61	6	M27416
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 SEMA5B ADAMTS1 ADAMTS9	2.33e-05	39	61	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 SEMA5B ADAMTS1 ADAMTS9	2.33e-05	39	61	4	MM15165
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	HSPG2 FBN2 ADAMTS1 ADAMTS9 LAMC2 CTSB	3.05e-05	140	61	6	M587
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS10 HSPG2 SEMA5B ADAMTS1 ADAMTS9 MUC5B MUC5AC	9.78e-05	250	61	7	M27554
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHA9 PCDHA10 PCDHA5 PCDHA4 DNMT3A	3.17e-09	24	85	5	24698270
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.08e-08	11	85	4	9655502
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 CILP2 SEMA5B ADAMTS1 ADAMTS9 PAPLN	3.13e-08	75	85	6	20637190
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	4.44e-08	15	85	4	15640798
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	7.72e-08	17	85	4	29911975
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	9.90e-08	18	85	4	15570159
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	9.90e-08	18	85	4	10662547
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	6.50e-07	28	85	4	15347688
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	HSPG2 FBN2 LAMC2 SERPINC1 CTSB KNG1	1.04e-06	135	85	6	28675934
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.09e-06	74	85	5	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.33e-06	77	85	5	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHA9 PCDHA10 PCDHA5 PCDHA4 PCDH20	1.61e-06	80	85	5	10716726
Pubmed	Proteins of the CNR family are multiple receptors for Reelin.	PCDHA9 PCDHA5 PCDHA4	3.05e-06	12	85	3	10612399
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS10 ADAMTS1 ADAMTS9	3.05e-06	12	85	3	25770910
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	5.90e-06	2	85	2	7513696
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	5.90e-06	2	85	2	34058148
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	5.90e-06	2	85	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	5.90e-06	2	85	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	5.90e-06	2	85	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	5.90e-06	2	85	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	5.90e-06	2	85	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	5.90e-06	2	85	2	22391959
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	5.90e-06	2	85	2	14718370
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	5.90e-06	2	85	2	35776514
Pubmed	ADAMTS1 and HSPG2 mRNA levels in cumulus cells are related to human oocyte quality and controlled ovarian hyperstimulation outcomes.	HSPG2 ADAMTS1	5.90e-06	2	85	2	31974739
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	5.90e-06	2	85	2	24327612
Pubmed	Sclerostin, preadipocyte factor-1 and bone mineral values in eumenorrheic adolescent athletes with different training patterns.	SOST DLK1	5.90e-06	2	85	2	32880010
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	5.90e-06	2	85	2	21653907
Pubmed	Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.	HSPG2 MUC5AC	5.90e-06	2	85	2	23836919
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	5.90e-06	2	85	2	36427316
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	5.90e-06	2	85	2	28607090
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	5.90e-06	2	85	2	23272068
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	5.90e-06	2	85	2	31030254
Pubmed	Abnormal expressions of ADAMTS-1, ADAMTS-9 and progesterone receptors are associated with lower oocyte maturation in women with polycystic ovary syndrome.	ADAMTS1 ADAMTS9	5.90e-06	2	85	2	30446843
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	5.90e-06	2	85	2	27729120
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	5.90e-06	2	85	2	23527003
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	5.90e-06	2	85	2	16540890
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	5.90e-06	2	85	2	36111525
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	5.90e-06	2	85	2	27845589
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	5.90e-06	2	85	2	27435107
Pubmed	Insulin-like growth factor II receptor-mediated intracellular retention of cathepsin B is essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.	IGF2R CTSB	5.90e-06	2	85	2	17507477
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	5.90e-06	2	85	2	26871672
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	5.90e-06	2	85	2	32348677
Pubmed	Sclerostin and Pref-1 have differential effects on bone mineral density and strength parameters in adolescent athletes compared with non-athletes.	SOST DLK1	5.90e-06	2	85	2	23579340
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	5.90e-06	2	85	2	11587997
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	5.90e-06	2	85	2	24332705
Pubmed	Exome sequencing in patients with microphthalmia, anophthalmia, and coloboma (MAC) from a consanguineous population.	TENM3 CDON	5.90e-06	2	85	2	32799327
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	5.90e-06	2	85	2	34656442
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.19e-05	57	85	4	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.27e-05	58	85	4	30377227
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	1.77e-05	3	85	2	27776277
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.77e-05	3	85	2	29286856
Pubmed	DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells.	ADAMTS9 DNMT3A	1.77e-05	3	85	2	33931579
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.77e-05	3	85	2	36675209
Pubmed	Differential gene expression of ADAMTS-1, ADAMTS-9 and TIMP-3 in periodontitis.	ADAMTS1 ADAMTS9	1.77e-05	3	85	2	36093887
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN2	1.77e-05	3	85	2	30201140
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	1.77e-05	3	85	2	29802623
Pubmed	Identification of two novel PCDHA9 mutations associated with Hirschsprung's disease.	PCDHA9 PCDHA10	1.77e-05	3	85	2	29477871
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	1.77e-05	3	85	2	34158522
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	1.77e-05	3	85	2	29604272
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	1.77e-05	3	85	2	19596978
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	1.77e-05	3	85	2	19556605
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	1.77e-05	3	85	2	21455588
Pubmed	[NRH2 induces cell apoptosis of cerebral tissues around hematomas after intracerebral hemorrhage through up-regulating proNGF, sortilin and p75NTR expressions].	NGF TNFRSF1B	1.77e-05	3	85	2	25854576
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	1.77e-05	3	85	2	20422702
Pubmed	ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.	ADAMTS1 ADAMTS9	1.77e-05	3	85	2	23562508
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	1.77e-05	3	85	2	19718741
Pubmed	TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.	MID2 TRIM35 TRIM59	1.82e-05	21	85	3	18248090
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HSPG2 ADAMTS9 CTSB CDON	1.89e-05	64	85	4	22261194
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	2.40e-05	68	85	4	11230163
Pubmed	GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.	ADAMTS1 ADAMTS9 PLXNA2	2.41e-05	23	85	3	29567669
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	FBN2 NFXL1 MUC5AC TP53BP1	2.85e-05	71	85	4	33541421
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	3.01e-05	72	85	4	10380929
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	IGF2R ADAMTS9 CDON	3.12e-05	25	85	3	29475039
Pubmed	NGF/TRKA Promotes ADAM17-Dependent Cleavage of P75 in Ovarian Cells: Elucidating a Pro-Tumoral Mechanism.	NGF TNFRSF1B	3.53e-05	4	85	2	35216240
Pubmed	NGF Modulates trkANGFR/p75NTR in αSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP).	NGF TNFRSF1B	3.53e-05	4	85	2	26569118
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	3.53e-05	4	85	2	31582416
Pubmed	Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis.	TNFRSF1B DNMT3A	3.53e-05	4	85	2	36169447
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	3.53e-05	4	85	2	25638393
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC	3.53e-05	4	85	2	17471237
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	3.53e-05	4	85	2	21097527
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	3.53e-05	4	85	2	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC5AC	3.53e-05	4	85	2	14984930
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	3.53e-05	4	85	2	23249391
Pubmed	Replicative verification of susceptibility genes previously identified from families with segregating developmental dysplasia of the hip.	HSPG2 TENM3	3.53e-05	4	85	2	34174923
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC5AC	3.53e-05	4	85	2	29869461
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	3.53e-05	4	85	2	18258655
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC	3.53e-05	4	85	2	23807779
Pubmed	The adaptor SASH1 acts through NOTCH1 and its inhibitor DLK1 in a 3D model of lumenogenesis involving CEACAM1.	SASH1 DLK1	3.53e-05	4	85	2	28823832
Pubmed	Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering.	HSPG2 LAMC2	3.53e-05	4	85	2	16219760
Pubmed	Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development.	DLK1 DNMT3A	3.53e-05	4	85	2	36907530
Pubmed	Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.	HSPG2 FBN2	3.53e-05	4	85	2	19506372
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC5AC	3.53e-05	4	85	2	12676567
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	PCDHA9 PCDHA10 PCDHA5 PCDHA4	3.54e-05	75	85	4	15372022
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	HSPG2 LAMC2 SERPINC1 CTSB KNG1	3.81e-05	153	85	5	25037231
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	HSPG2 PAPLN LAMC2 SERPINC1 CTSB	5.78e-05	167	85	5	22159717
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC5AC	5.87e-05	5	85	2	11062147
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	SEMA5B PLXNA2	5.87e-05	5	85	2	25313870
Pubmed	Increased plasticity of genomic imprinting of Dlk1 in brain is due to genetic and epigenetic factors.	IGF2R DLK1	5.87e-05	5	85	2	15859358
Pubmed	Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation.	IGF2R DNMT3A	5.87e-05	5	85	2	20132320
Interaction	PCDHA10 interactions	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.85e-06	22	83	4	int:PCDHA10
Interaction	PCDHA7 interactions	PCDHA9 PCDHA10 PCDHA4	2.37e-05	14	83	3	int:PCDHA7
Cytoband	15q15-q21	TLN2 TP53BP1	2.03e-05	4	85	2	15q15-q21
Cytoband	5q31	PCDHA9 PCDHA10 PCDHA5 PCDHA4	6.47e-05	115	85	4	5q31
Cytoband	6q24.3	SASH1 STXBP5	1.84e-04	11	85	2	6q24.3
Cytoband	14q24.2	PAPLN ZFYVE1	9.89e-04	25	85	2	14q24.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHA9 PCDHA10 PCDHA5 PCDHA4	2.33e-03	298	85	4	chr5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr2p23	PLB1 PRR30 DNMT3A	2.72e-03	149	85	3	chr2p23
Cytoband	12q24.33	FZD10 ADGRD1	3.62e-03	48	85	2	12q24.33
Cytoband	Ensembl 112 genes in cytogenetic band chr1q25	PAPPA2 LAMC2 SERPINC1	3.75e-03	167	85	3	chr1q25
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS1 ADAMTS9	3.58e-05	19	62	3	50
GeneFamily	Clustered protocadherins	PCDHA9 PCDHA10 PCDHA5 PCDHA4	6.83e-05	64	62	4	20
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	2.33e-03	21	62	2	648
GeneFamily	Ring finger proteins	RNF5 MID2 TRIM35 MKRN2 TRIM59	2.51e-03	275	62	5	58
GeneFamily	PWWP domain containing	ZCWPW1 DNMT3A	2.56e-03	22	62	2	1147
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	MID2 TRIM35 TRIM59	4.25e-03	95	62	3	59
Coexpression	NABA_MATRISOME	ADAMTS10 PAPPA2 HSPG2 CILP2 FBN2 SEMA5B ADAMTS1 ADAMTS9 OTOGL NGF PAPLN LAMC2 SERPINC1 MUC5B CCL19 CTSB MUC5AC PLXNA2 KNG1	4.24e-10	1008	85	19	MM17056
Coexpression	NABA_MATRISOME	ADAMTS10 PAPPA2 HSPG2 CILP2 FBN2 SEMA5B ADAMTS1 ADAMTS9 NGF PAPLN LAMC2 SERPINC1 MUC5B CCL19 CTSB MUC5AC PLXNA2 KNG1	4.06e-09	1026	85	18	M5889
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS10 PAPPA2 SEMA5B ADAMTS1 ADAMTS9 NGF SERPINC1 MUC5B CCL19 CTSB MUC5AC PLXNA2 KNG1	7.20e-07	738	85	13	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS10 PAPPA2 SEMA5B ADAMTS1 ADAMTS9 NGF SERPINC1 MUC5B CCL19 CTSB MUC5AC PLXNA2 KNG1	8.75e-07	751	85	13	M5885
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 PAPPA2 ADAMTS1 ADAMTS9 SERPINC1 CTSB KNG1	1.26e-05	238	85	7	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 PAPPA2 ADAMTS1 ADAMTS9 SERPINC1 CTSB KNG1	1.40e-05	242	85	7	MM17062
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_3_CELL	ADAMTS10 FBN2 TENM3 ADAMTS9 DLK1 CDON	2.22e-05	174	85	6	M45676
Coexpression	TGFB_UP.V1_DN	HSPG2 SH3TC2 ADAMTS1 MAPKBP1 PLXNA2 TP53BP1	3.75e-05	191	85	6	M2838
Coexpression	GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP	FBN2 IGF2R SASH1 TSPAN14 TNFRSF1B CTSB	4.85e-05	200	85	6	M4966
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_UP	MIS12 SERPINC1 CDCA5 PCDH20 ADGRD1 DNMT3A	4.85e-05	200	85	6	M3968
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	CACNA2D1 IGF2R SASH1 TENM3 ADAMTS1 CR2 PLXNA2 MEIS1 ADGRD1 TP53BP1	1.14e-04	721	85	10	M1999
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	PAPPA2 CACNA2D1 ZCWPW1 FBN2 IGF2R TENM3 ADAMTS1 ADAMTS9 HJURP NFXL1 DLK1 CCL19 PCDH20 PLXNA2 MEIS1 DNMT3A	1.30e-07	827	84	16	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	PAPPA2 CACNA2D1 ZCWPW1 FBN2 IGF2R TENM3 ADAMTS1 HJURP DLK1 CCL19 KAT6B TRIM59 PCDH20 PLXNA2 MEIS1 CDON	1.39e-07	831	84	16	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	PAPPA2 CACNA2D1 FBN2 IGF2R TENM3 DLK1 CCL19 MEIS1 DNMT3A	7.43e-06	337	84	9	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	PAPPA2 CACNA2D1 ZCWPW1 FBN2 IGF2R TENM3 ADAMTS9 HJURP DEPDC1 DLK1 MEIS1 CDON DNMT3A	1.03e-05	773	84	13	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	PAPPA2 CACNA2D1 ZCWPW1 FBN2 TENM3 HJURP NFXL1 PCDH20 MEIS1	4.07e-05	418	84	9	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500	PAPPA2 CACNA2D1 FBN2 TENM3 ADAMTS1 HJURP TRIM59 PCDH20 MEIS1	4.46e-05	423	84	9	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	HSPG2 SASH1 TENM3 ADAMTS1 DLK1 CCL19 MEIS1 ADGRD1 CDON	5.74e-05	437	84	9	GSM777046_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	HSPG2 CACNA2D1 SASH1 TENM3 ADAMTS1 ADAMTS9 CCL19 PLXNA2 MEIS1	6.59e-05	445	84	9	GSM777043_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	PAPPA2 CACNA2D1 FBN2 IGF2R TENM3 DLK1 CCL19 MEIS1	7.98e-05	354	84	8	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	CACNA2D1 ZCWPW1 FBN2 ADAMTS9 HJURP DLK1 MEIS1 CDON	8.30e-05	356	84	8	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	ADAMTS10 FBN2 ADAMTS1 PCDHA10 PAPLN PCDHA5 PCDHA4	1.25e-04	281	84	7	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	ADAMTS10 FBN2 ADAMTS1 PCDHA10 PAPLN PCDHA5 PCDHA4	1.25e-04	281	84	7	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Stromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1	SH3TC2 MID2 ADAMTS9 AIRE LAMC2 CCL19 PLXNA2 ADGRD1	2.22e-04	411	84	8	GSM854302_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	PAPPA2 ZCWPW1 FBN2 TENM3 ADAMTS9 HJURP NFXL1 KAT6B PLXNA2 MEIS1 CDON	2.55e-04	783	84	11	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000	PAPPA2 ZCWPW1 FBN2 TENM3 ADAMTS1 DLK1 KAT6B PLXNA2 MEIS1 CDON DNMT3A	2.97e-04	797	84	11	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100	ADAMTS9 HJURP DLK1 MEIS1	3.46e-04	84	84	4	gudmap_developingGonad_e14.5_ epididymis_100
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_100	ADAMTS9 HJURP DLK1 MEIS1	3.78e-04	86	84	4	gudmap_developingGonad_e16.5_epididymis_100
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000	PAPPA2 FBN2 TENM3 PLXNA2 MEIS1 DNMT3A	3.82e-04	240	84	6	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000
ToppCell	(5)_Fibroblast-J_(Lipofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CILP2 ADAMTS1 NGF FZD10 PAPLN CCL19 MEIS1 CDON	4.06e-09	196	85	8	afa29399decd17fda7d63add5039ff778627ccc2
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CILP2 ADAMTS1 NGF FZD10 PAPLN CCL19 MEIS1 CDON	4.57e-09	199	85	8	675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CILP2 ADAMTS1 NGF FZD10 PAPLN CCL19 MEIS1 CDON	4.57e-09	199	85	8	97d74985018816754d11a55b9fb689690ecb1374
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA2D1 PCDHA9 ADAMTS1 ADAMTS9 OTOGL PCDHA4 ADGRD1	5.33e-08	179	85	7	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR161 HJURP MAGI3 SERPINC1 DEPDC1 CDCA5	1.23e-06	179	85	6	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TLN2 MUC5B LRP1B UNC79	1.44e-06	184	85	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TLN2 MUC5B LRP1B UNC79	1.44e-06	184	85	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TLN2 MUC5B LRP1B UNC79	1.44e-06	184	85	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX2 PAPPA2 KANK1 LRP1B ADGRD1 CDON	1.44e-06	184	85	6	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 NGF PAPLN TLN2 CCL19 CDON	1.49e-06	185	85	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 NGF PAPLN TLN2 CCL19 CDON	1.49e-06	185	85	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 NGF PAPLN TLN2 CCL19 CDON	1.49e-06	185	85	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 SH3TC2 ADAMTS9 NGF TLN2 CCL19	1.58e-06	187	85	6	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 SH3TC2 ADAMTS9 NGF TLN2 CCL19	1.58e-06	187	85	6	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 SH3TC2 ADAMTS9 NGF TLN2 CCL19	1.58e-06	187	85	6	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP2 ADAMTS1 NGF PAPLN CCL19 CDON	2.21e-06	198	85	6	c66097ae9ba0b50561083c423565665958ef0bb8
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KANK1 FBN2 ZSCAN10 TENM3 NGF	6.11e-06	135	85	5	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	CACNA2D1 TENM3 PAPLN CCL19 CR2	7.04e-06	139	85	5	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PLB1 PCDHA9 CCDC187 LAMC2	7.82e-06	66	85	4	6db3933fde0eee67dc5da85d7008c4fef9f684f5
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PLB1 PCDHA9 CCDC187 LAMC2	7.82e-06	66	85	4	c522722e99922caf4abe7103f1492ea96d3786a5
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PLB1 PCDHA9 CCDC187 LAMC2	7.82e-06	66	85	4	c6888ebcaba37486d9a12ad4d76669fb4e3c8fba
ToppCell	Striatum-Neuronal-Inhibitory\|Striatum / BrainAtlas - Mouse McCarroll V32	GPR161 IQSEC3 PCDHA9 NGF CR2	1.27e-05	157	85	5	c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR161 TENM3 NGF CCL19 MEIS1	1.52e-05	163	85	5	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR161 TENM3 NGF CCL19 MEIS1	1.52e-05	163	85	5	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 STXBP5 STK33 UNC79 KNG1	1.62e-05	165	85	5	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL NGF CCL19 LRP1B UNC79	1.81e-05	169	85	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 OTOGL PAPLN LRP1B ADGRD1	1.87e-05	170	85	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZCWPW1 HJURP DEPDC1 CDCA5 TRIM59	1.97e-05	172	85	5	c06ca5d075937747952ed915c9db39a9f62072f9
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 KANK1 TENM3 ADGRD1 CDON	2.03e-05	173	85	5	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL NGF CCL19 LRP1B UNC79	2.03e-05	173	85	5	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL NGF CCL19 LRP1B UNC79	2.03e-05	173	85	5	649b08a409095592cccf31883be69c754411280d
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 IQSEC3 OTOGL TLN2 CCL19	2.09e-05	174	85	5	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPR161 HJURP SERPINC1 DEPDC1 CDCA5	2.20e-05	176	85	5	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOST TENM3 SEMA5B NGF CR2	2.26e-05	177	85	5	4553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQSEC3 KANK1 MKRN2 NGF UNC79	2.39e-05	179	85	5	b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPG2 SOST SASH1 ADAMTS1 ADAMTS9	2.39e-05	179	85	5	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	CACNA2D1 SH3TC2 ADAMTS9 NGF ADGRD1	2.45e-05	180	85	5	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP20DC LAMC2 MUC5B DEPDC1 CDCA5	2.52e-05	181	85	5	e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 SEMA5B ADAMTS1 ADAMTS9 NGF	2.52e-05	181	85	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	CACNA2D1 TENM3 AIRE LAMC2 CCL19	2.52e-05	181	85	5	94680f8dbdf22d83801abc0819417751d363fb12
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 CILP2 ZCWPW1 TENM3 PCDH20	2.59e-05	182	85	5	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	ADAMTS9 STK33 MAGI3 LAMC2 PLXNA2	2.66e-05	183	85	5	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOST MAGI3 LRP1B PCDH20 ADGRD1	2.66e-05	183	85	5	c7e94fe3e7669db9304b249979fef7a69c30a143
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG4B HSPG2 DOK4 MAGI3 LAMC2	2.73e-05	184	85	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FAM117A SEMA5B ADAMTS1 ADAMTS9 NGF	2.73e-05	184	85	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CILP2 FBN2 TENM3 DLK1 MEIS1	2.80e-05	185	85	5	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN2 NGF DLK1 ADGRD1 CDON	2.87e-05	186	85	5	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CACNA2D1 SEMA5B ADAMTS1 ADAMTS9 NGF	2.87e-05	186	85	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	GPR161 HSPG2 ADAMTS9 PLXNA2 CDON	2.95e-05	187	85	5	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PLEKHG4B HSPG2 FBN2 MAGI3 LAMC2	2.95e-05	187	85	5	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS10 ADAMTS9 OTOGL MEIS1 ADGRD1	2.95e-05	187	85	5	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	COVID-19-kidney-Mito-rich_Distal\|kidney / Disease (COVID-19 only), tissue and cell type	PAPPA2 ADAMTS1 FZD10 LRP1B KNG1	2.95e-05	187	85	5	2ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell	Pericytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	GPR161 CACNA2D1 SEMA5B FZD10 CCL19	2.95e-05	187	85	5	35f25780d113f60bf4c13749013c09612ee4ff41
ToppCell	MatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)\|MatrixFB / shred on cell class and cell subclass (v4)	MIS12 HJURP DEPDC1 CDCA5 TRIM59	3.02e-05	188	85	5	b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	CILP2 FBN2 TENM3 DLK1 MEIS1	3.02e-05	188	85	5	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 ADAMTS1 LAMC2 MAPKBP1 LRP1B	3.10e-05	189	85	5	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HJURP DEPDC1 CDCA5 TRIM59 MEIS1	3.10e-05	189	85	5	d049f33115610bda4489968759f754730698b9cd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 ADAMTS1 LAMC2 MAPKBP1 LRP1B	3.10e-05	189	85	5	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	FBN2 TENM3 LAMC2 DLK1 CDON	3.18e-05	190	85	5	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADAMTS1 ADAMTS9 NGF TSPAN14 PLXNA2	3.18e-05	190	85	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SH3TC2 KANK1 SASH1 TRIM59 MEIS1	3.18e-05	190	85	5	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	SASH1 HJURP DEPDC1 CTSB CDCA5	3.26e-05	191	85	5	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CACNA2D1 SEMA5B ADAMTS1 ADAMTS9 NGF	3.26e-05	191	85	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	HSPG2 SH3TC2 SOST ADAMTS1 LRP1B	3.34e-05	192	85	5	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PAPPA2 TENM3 ADAMTS9 DLK1 CDON	3.34e-05	192	85	5	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	P15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOST KANK1 SEMA5B NGF CCL19	3.34e-05	192	85	5	a476895b7b252c388d6346eacbc72f0115b1443e
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 TENM3 NGF CCL19 ADGRD1	3.42e-05	193	85	5	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 KANK1 TENM3 ADGRD1 CDON	3.42e-05	193	85	5	858a186804b36d45957238d3d3eed2768b961641
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 KANK1 TENM3 ADGRD1 CDON	3.42e-05	193	85	5	7865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 KANK1 TENM3 ADGRD1 CDON	3.42e-05	193	85	5	025836c5c5a711e477c326559e618e47cae42d11
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SASH1 ADAMTS1 ADAMTS9 PLXNA2	3.51e-05	194	85	5	f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SASH1 ADAMTS1 ADAMTS9 PLXNA2	3.51e-05	194	85	5	04b1acc2e879feafb43f75435281c5acd8d23be2
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	HSPG2 SASH1 ADAMTS1 ADAMTS9 PLXNA2	3.51e-05	194	85	5	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	PAPPA2 ADAMTS1 LAMC2 LRP1B KNG1	3.69e-05	196	85	5	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	SH3TC2 ADAMTS1 NGF MEIS1 ADGRD1	3.69e-05	196	85	5	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	Control-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	SH3TC2 ADAMTS1 NGF MEIS1 ADGRD1	3.69e-05	196	85	5	1ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 ADAMTS9 HJURP DEPDC1 CDCA5	3.69e-05	196	85	5	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FBN2 SEMA5B DLK1 CCL19 ADGRD1	3.69e-05	196	85	5	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TENM3 ADAMTS1 DLK1 CCL19 MEIS1	3.78e-05	197	85	5	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	distal-mesenchymal-Lipofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP2 ADAMTS1 NGF CCL19 CDON	3.78e-05	197	85	5	865010edcd7e3f79f505fcef7b33882095994aa8
ToppCell	distal-mesenchymal-Lipofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP2 ADAMTS1 NGF CCL19 CDON	3.78e-05	197	85	5	ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 ADAMTS9 HJURP DEPDC1 CDCA5	3.78e-05	197	85	5	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-T_reticular\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 NGF PAPLN CCL19 MEIS1	3.87e-05	198	85	5	5c96778cf5623c662c2259fe70f8665c14a161dd
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PAPPA2 CILP2 TENM3 OTOGL LRP1B	3.87e-05	198	85	5	c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCell	Control-Stromal\|Control / Disease state, Lineage and Cell class	SH3TC2 ADAMTS1 NGF MEIS1 ADGRD1	3.87e-05	198	85	5	ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PAPPA2 CILP2 TENM3 OTOGL LRP1B	3.87e-05	198	85	5	55f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP2 KANK1 FBN2 TENM3 FZD10	3.87e-05	198	85	5	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 CILP2 PAPLN CCL19 CDON	3.96e-05	199	85	5	f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TENM3 ADAMTS1 CCL19 MEIS1 ADGRD1	3.96e-05	199	85	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	distal-1-mesenchymal-Lipofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP2 ADAMTS1 NGF CCL19 CDON	3.96e-05	199	85	5	a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 CILP2 PAPLN CCL19 CDON	3.96e-05	199	85	5	c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KANK1 HJURP DEPDC1 CDCA5 PCDH20	4.06e-05	200	85	5	02594c1edbc9f2cf831639cd83363abd2551cb94
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KANK1 HJURP DEPDC1 CDCA5 PCDH20	4.06e-05	200	85	5	46521d83b917b0357601db8783c8da6b73730d60
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	JAK3 SLC37A2 MUC5B TNFRSF1B CTSB	4.06e-05	200	85	5	74ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CACNA2D1 CILP2 ADAMTS1 NGF PCDHA4	4.06e-05	200	85	5	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SOST CR2 ADGRD1	1.51e-04	54	85	3	98b31718fa200432cf86b59a52484da101219f96
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SOST CR2 ADGRD1	1.51e-04	54	85	3	872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLEKHG4B TENM3 MEIS1 ADGRD1	1.62e-04	143	85	4	27e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLEKHG4B TENM3 MEIS1 ADGRD1	1.62e-04	143	85	4	4edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CILP2 STK33 NGF CCDC187	1.71e-04	145	85	4	ac41c6c02b7d78162b86222983688f54d04ac47d
Disease	1,5 anhydroglucitol measurement	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.37e-06	29	84	4	EFO_0008009
Disease	alpha-tocopherol measurement	CACNA2D1 CFAP20DC STK33	2.45e-05	20	84	3	EFO_0007898
Disease	pulmonary sarcoidosis (is_marker_for)	NGF CCL19 TNFRSF1B	1.04e-04	32	84	3	DOID:13406 (is_marker_for)
Disease	visceral adipose tissue measurement, body mass index	PCDHA9 PCDHA10 PCDHA5 PCDHA4	1.14e-04	87	84	4	EFO_0004340, EFO_0004765
Disease	neutrophil count	PAPPA2 PCDHA9 STXBP5 RRP12 ZNF316 NGF MAGI3 PCDHA10 TLN2 PCDHA5 PCDHA4 TSPAN14 DLK1	1.39e-04	1382	84	13	EFO_0004833
Disease	Nephronophthisis, familial juvenile	ADAMTS9 MAPKBP1	1.67e-04	7	84	2	C1855681
Disease	Pituitary stalk interruption syndrome	GPR161 CDON	1.67e-04	7	84	2	C4053775
Disease	plasma renin activity measurement	TENM3 KNG1	2.85e-04	9	84	2	EFO_0006828
Disease	decadienedioic acid (C10:2-DC) measurement	PAPLN ZFYVE1	3.55e-04	10	84	2	EFO_0800598
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	JAK3 DNMT3A	4.33e-04	11	84	2	DOID:5603 (is_implicated_in)
Disease	spontaneous preterm birth, parental genotype effect measurement	CACNA2D1 STK33	4.33e-04	11	84	2	EFO_0005939, EFO_0006917
Disease	pulmonary fibrosis	MUC5B MUC5AC	4.33e-04	11	84	2	EFO_0009448
Disease	neutrophil count, basophil count	PCDHA9 ZNF316 PCDHA10 PCDHA5 PCDHA4	4.57e-04	224	84	5	EFO_0004833, EFO_0005090
Disease	asthma (is_marker_for)	NGF MUC5B CCL19 MUC5AC	4.70e-04	126	84	4	DOID:2841 (is_marker_for)
Disease	Alzheimer disease	ZCWPW1 SASH1 ADAMTS1 TLN2 TSPAN14 CTSB CDON	4.73e-04	485	84	7	MONDO_0004975
Disease	colon carcinoma (is_marker_for)	IGF2R TNFRSF1B	6.12e-04	13	84	2	DOID:1520 (is_marker_for)
Disease	urate measurement, spine bone mineral density	PAPPA2 CACNA2D1 SH3TC2	6.13e-04	58	84	3	EFO_0004531, EFO_0007701
Disease	Allergic Reaction	CCL19 TNFRSF1B KNG1	7.81e-04	63	84	3	C1527304
Disease	Hypersensitivity	CCL19 TNFRSF1B KNG1	8.18e-04	64	84	3	C0020517
Disease	Spondyloepiphyseal Dysplasia	HSPG2 SOST	9.36e-04	16	84	2	C0038015
Disease	maximal oxygen uptake measurement, response to exercise	SASH1 ADAMTS1	9.36e-04	16	84	2	EFO_0004887, EFO_0007768
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 SOST	9.36e-04	16	84	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 SOST	9.36e-04	16	84	2	C4551479
Disease	Schwartz-Jampel Syndrome	HSPG2 SOST	9.36e-04	16	84	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 SOST	9.36e-04	16	84	2	C0025237
Disease	Malignant neoplasm of breast	SEMA5B ADAMTS1 OTOGL NFYC CYB5R4 KAT6B PCDH20 MEIS1 TP53BP1 DNMT3A	9.42e-04	1074	84	10	C0006142
Disease	Van Buchem disease	HSPG2 SOST	1.06e-03	17	84	2	C0432272
Disease	acute kidney failure (is_marker_for)	SERPINC1 TNFRSF1B	1.06e-03	17	84	2	DOID:3021 (is_marker_for)
Disease	otitis media (biomarker_via_orthology)	CTSB MUC5AC	1.06e-03	17	84	2	DOID:10754 (biomarker_via_orthology)
Disease	neuroticism measurement, cognitive function measurement	PCDHA9 TENM3 PCDHA10 PCDHA5 PCDHA4 FPGT LRP1B	1.17e-03	566	84	7	EFO_0007660, EFO_0008354
Disease	Child Behaviour Checklist assessment	KANK1 TENM3	1.19e-03	18	84	2	EFO_0005661
Disease	Osteochondrodysplasias	HSPG2 SOST	1.33e-03	19	84	2	C0029422
Disease	glomerulonephritis (is_marker_for)	NGF TNFRSF1B	1.33e-03	19	84	2	DOID:2921 (is_marker_for)
Disease	Dyschondroplasias	HSPG2 SOST	1.33e-03	19	84	2	C0013366
Disease	Juvenile Myelomonocytic Leukemia	JAK3 DNMT3A	1.33e-03	19	84	2	C0349639
Disease	Multiple Epiphyseal Dysplasia	HSPG2 SOST	1.47e-03	20	84	2	C0026760
Disease	mosaic loss of chromosome Y measurement	KANK1 FAM117A DLK1	1.56e-03	80	84	3	EFO_0007783
Disease	Lewy Body Disease	IGF2R NGF	1.78e-03	22	84	2	C0752347
Disease	Allodynia	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0458247
Disease	Mechanical Allodynia	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C2936719
Disease	Hyperalgesia, Secondary	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0751212
Disease	Hyperalgesia, Primary	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0751211
Disease	Hyperalgesia, Thermal	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0751214
Disease	Tactile Allodynia	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0751213
Disease	Hyperalgesia	CACNA2D1 NGF KNG1	1.80e-03	84	84	3	C0020429
Disease	pulse pressure measurement	PAPPA2 CILP2 PCDHA9 FBN2 PCDHA10 TLN2 PCDHA5 PCDHA4 TSPAN14 TRIM59 MEIS1	1.95e-03	1392	84	11	EFO_0005763
Disease	Cardiac Arrhythmia	CACNA2D1 KNG1	2.30e-03	25	84	2	C0003811
Disease	vital capacity	ADAMTS10 PAPPA2 HSPG2 SH3TC2 PCDHA9 ADAMTS1 PCDHA10 PCDHA5 PCDHA4 MAPKBP1	2.66e-03	1236	84	10	EFO_0004312
Disease	Nephrotic Syndrome	KANK1 SERPINC1	2.68e-03	27	84	2	C0027726
Disease	Sezary Syndrome	TNFRSF1B DNMT3A	2.68e-03	27	84	2	C0036920
Disease	chronic obstructive pulmonary disease (is_marker_for)	MUC5B TNFRSF1B MUC5AC	2.71e-03	97	84	3	DOID:3083 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPVVCSKLTEVPRVC	CDCA5	181	Q96FF9
GADSVAPCTPRSCGK	CCDC187	1001	A0A096LP49
PQCPTIKEIRDQGSC	CTSB	91	P07858
PEASRAVENGCCTPK	DNMT3A	126	Q9Y6K1
SSCISKPEQCGPEGV	ADGRD1	91	Q6QNK2
ASVPCSVAPEKSVCR	FAM117A	66	Q9C073
TCHGSPVDICTAKPR	SERPINC1	31	P01008
SKPCSRAITPECVVG	C1orf147	231	Q96MC9
CPAGFIDKTCSRPVT	DLK1	196	P80370
GTPCRPDTVDICVSG	ADAMTS10	661	Q9H324
RCRSCSGDVTPAPVE	AIRE	471	O43918
PCSEPVKGTGALRDC	HJURP	326	Q8NCD3
KSCPECRVISEFVIP	MKRN2	286	Q9H000
VCDEGSVSVQCKPLP	MUC5B	5436	Q9HC84
ECAPGKPTLVCSSAV	PCDHA9	731	Q9Y5H5
TKRPEEVCGPTQFRC	HSPG2	361	P98160
ECAKEVKPASTRPCA	ADAMTS1	891	Q9UHI8
GVAVTLTSCCIPRPK	JAK3	466	P52333
DPIPICSFCLGTKES	KAT6B	211	Q8WYB5
FEKCELATCTPREPG	MEIS1	91	O00470
AVDCGKPPRESVATV	PCDH20	611	Q8N6Y1
GSVECVCPTRYEGPK	LRP1B	4341	Q9NZR2
TCCVVSGKAPSPGDV	MAGI3	56	Q5TCQ9
ETKCRDPNPVDSGCR	NGF	176	P01138
SKFSLPCTEDVPTCG	NFXL1	401	Q6ZNB6
AEDCCLSVTQKPIPG	CCL19	26	Q99731
SCPQCDTIVAKPVEE	PCNX2	311	A6NKB5
TSGPVRLCIGECKPE	PLXNA2	926	O75051
SKPRCCSLEGIVDVP	DEPDC1	416	Q5TB30
DVTVCSPKECASRGV	KANK1	636	Q14678
VLCCETPKGCPVTST	MUC5AC	2211	P98088
RVLCCETPKGCPVTS	MUC5AC	3316	P98088
PTEAVCTRGKPTLLC	PCDHA5	726	Q9Y5H7
GAVTDKEKERPPSCC	IQSEC3	146	Q9UPP2
CSGLPDPVRGKECTF	ELAPOR2	91	A8MWY0
GSSECTERPPCTTKD	ELAPOR2	336	A8MWY0
AEPREVKATGNSTPC	NFYC	331	Q13952
TEGACGPVKPTLVCS	PCDHA10	726	Q9Y5I2
ACAPGKPTLVCSSAV	PCDHA4	731	Q9UN74
CADTAPTPKSELCRE	PAPPA2	771	Q9BXP8
VEKSASCAPLCTPGV	FZD10	201	Q9ULW2
TVAKCSKGPCEEPAA	SLC37A2	271	Q8TED4
ACATLPRPVAKEECS	ADAMTS9	1221	Q9P2N4
VPPTCEEARCKSLGR	CR2	206	P20023
TKTSIRDPCAGPVCD	CACNA2D1	826	P54289
ENVTECPKPCDTGCT	CENPJ	501	Q9HC77
KVPVCLTSAVPDCGQ	CDON	1156	Q4KMG0
CLGEGTTPKPRTECQ	MAPKBP1	1346	O60336
CTCPPKRRSSVTFED	GPR161	421	Q8N6U8
TTPCKVDVSEEAPCQ	KRTAP16-1	476	A8MUX0
EPVGCRSDGTCVCKP	LAMC2	581	Q13753
TKICVGCPRDIPTNS	KNG1	261	P01042
VRPFPGAVTKSECCC	FBN2	716	P35556
PDEKSVCLRGCPKVT	DOK4	46	Q8TEW6
IFPDIPECSGKTSCI	FPGT	401	O14772
KCPSISTPECREDQF	OTOGL	1976	Q3ZCN5
TPVVCPDEVRMDGCT	IGF2R	1791	P11717
VQVSPTCPVCKDRAS	TRIM35	51	Q9UPQ4
CVCSSKTRVPPVLVV	STK33	26	Q9BYT3
ETRPERQECPVCKAG	RNF5	56	Q99942
DPTQITFPGCICVKT	SETMAR	66	Q53H47
CRALCSVTPPAEKEG	SH3TC2	181	Q8TF17
PEPCNCSEETTRLAK	PLB1	236	Q6P1J6
SKVLVCICGPVPFTE	CYB5R4	486	Q7L1T6
DGPCRSAKPVTELVC	SOST	91	Q9BQB4
EGTVVPEDRCKSPTS	STXBP5	701	Q5T5C0
PCFPEGLVKSCSETL	RRP12	316	Q5JTH9
SCDEESCSKEPRVIP	BTG4	146	Q9NY30
PCKEVQSSCRVVPED	AKAP17A	521	Q02040
RCGSCQKTPEPVIKA	CFAP20DC	486	Q6ZVT6
PERPGTSAACVEFKC	CILP2	981	Q8IUL8
CPVSETFGRLCPVSE	nan	6	Q6ZQT0
CPVSETFGRLCPVSE	nan	46	Q6ZQT0
CPVSETFGRLCPVSE	nan	76	Q6ZQT0
ACKGACPSSAKEEPR	ZCWPW1	576	Q9H0M4
EPPQECVECGKSFSR	ZSCAN10	666	Q96SZ4
PDCDISPVQIRKCTE	MIS12	51	Q9H081
VDGTPCEPGKRDVCV	PAPLN	136	O95428
RTPDCAVISDRAPKC	PLEKHG4B	1136	Q96PX9
LTEICRKPVSPGCIS	SASH1	1166	O94885
KGTECDVPTTQCIDP	TENM3	571	Q9P273
EFKTCNPEGCPEVRR	SEMA5B	761	Q9P283
VTDPSCPASVLKCAE	TP53BP1	1921	Q12888
GFCDSCSSKTRPVPE	ZFYVE1	626	Q9HBF4
GRPETTCDVCGKVFP	ZNF316	341	A6NFI3
ACAKVVSPTISSPVC	TLN2	721	Q9Y4G6
SREKCGVPFSCCVPD	TSPAN14	176	Q8NG11
RPGTETSDVVCKPCA	TNFRSF1B	151	P20333
PPRDAVKTCITCEVS	MID2	146	Q9UJV3
SGSPGVVERCVPSEK	PRR30	186	Q53SZ7
CPNCRSITEIAPTGI	TRIM59	56	Q8IWR1
SCIDRCDIEKPPTQA	UNC79	1521	Q9P2D8