Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RAP1GAP GBF1 KALRN TAGAP TBC1D24 NF1 PLEKHG6 SRGAP3 RASGEF1B GPSM2 C9orf72 ARHGAP21	3.63e-05	507	115	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RAP1GAP GBF1 KALRN TAGAP TBC1D24 NF1 PLEKHG6 SRGAP3 RASGEF1B GPSM2 C9orf72 ARHGAP21	3.63e-05	507	115	12	GO:0030695
GeneOntologyMolecularFunction	phosphatidylethanolamine binding	GABARAPL2 ESYT2 NF1	1.69e-04	19	115	3	GO:0008429
MousePheno	abnormal spleen size	CYLD SMG1 RAP1GAP GLS2 ATR TAGAP CAMK4 FLVCR1 FAM161B FOCAD LHCGR AP4E1 ESYT2 LIPA BTK LRRTM2 GSTCD CIAO2B C9orf72 KIT M6PR DNAH11	5.42e-06	1203	90	22	MP:0002224
Domain	ARM-type_fold	SMG1 GBF1 ATR MAP3K1 FOCAD AP4E1 NF1 HEATR9 DIAPH3 TARBP1 TANGO6	7.29e-06	339	114	11	IPR016024
Domain	AAA	ABCA12 RNF213 AK9 ABCA9 DNAH9 DNAH11	2.55e-04	144	114	6	SM00382
Domain	AAA+_ATPase	ABCA12 RNF213 AK9 ABCA9 DNAH9 DNAH11	2.55e-04	144	114	6	IPR003593
Domain	FATC	SMG1 ATR	3.65e-04	5	114	2	PF02260
Domain	SEC14	KALRN NF1 BNIPL	4.62e-04	25	114	3	SM00516
Domain	Lipase_euk	LIPF LIPA	5.45e-04	6	114	2	IPR025483
Domain	Abhydro_lipase	LIPF LIPA	5.45e-04	6	114	2	PF04083
Domain	FAT	SMG1 ATR	5.45e-04	6	114	2	PS51189
Domain	FATC	SMG1 ATR	5.45e-04	6	114	2	PS51190
Domain	AB_hydrolase_lipase	LIPF LIPA	5.45e-04	6	114	2	IPR006693
Domain	FATC_dom	SMG1 ATR	5.45e-04	6	114	2	IPR003152
Domain	PIK_FAT	SMG1 ATR	5.45e-04	6	114	2	IPR014009
Domain	FATC	SMG1 ATR	5.45e-04	6	114	2	SM01343
Domain	CRAL_TRIO	KALRN NF1 BNIPL	5.82e-04	27	114	3	PS50191
Domain	CRAL-TRIO_dom	KALRN NF1 BNIPL	6.49e-04	28	114	3	IPR001251
Domain	GoLoco	RAP1GAP GPSM2	7.60e-04	7	114	2	SM00390
Domain	GoLoco	RAP1GAP GPSM2	7.60e-04	7	114	2	PF02188
Domain	SWIM	ZSWIM2 MAP3K1	7.60e-04	7	114	2	PF04434
Domain	GoLoco_motif	RAP1GAP GPSM2	7.60e-04	7	114	2	IPR003109
Domain	GOLOCO	RAP1GAP GPSM2	7.60e-04	7	114	2	PS50877
Domain	DHC_N1	DNAH9 DNAH11	1.01e-03	8	114	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH9 DNAH11	1.01e-03	8	114	2	IPR013594
Domain	ZF_SWIM	ZSWIM2 MAP3K1	1.29e-03	9	114	2	PS50966
Domain	Znf_SWIM	ZSWIM2 MAP3K1	1.29e-03	9	114	2	IPR007527
Domain	ARM-like	SMG1 ATR AP4E1 NF1 HEATR9 TARBP1 TANGO6	1.35e-03	270	114	7	IPR011989
Domain	Rho_GTPase_activation_prot	TAGAP NF1 SRGAP3 ARHGAP21	2.07e-03	88	114	4	IPR008936
Domain	CRAL_TRIO_2	NF1 BNIPL	2.34e-03	12	114	2	PF13716
Domain	ABC_A	ABCA12 ABCA9	2.34e-03	12	114	2	IPR026082
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH11	3.20e-03	14	114	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DNAH11	3.20e-03	14	114	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DNAH11	3.20e-03	14	114	2	IPR013602
Domain	DHC_N2	DNAH9 DNAH11	3.20e-03	14	114	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH9 DNAH11	3.20e-03	14	114	2	IPR011704
Domain	MT	DNAH9 DNAH11	3.20e-03	14	114	2	PF12777
Domain	AAA_8	DNAH9 DNAH11	3.20e-03	14	114	2	PF12780
Domain	AAA_5	DNAH9 DNAH11	3.20e-03	14	114	2	PF07728
Domain	DHC_fam	DNAH9 DNAH11	3.68e-03	15	114	2	IPR026983
Domain	Dynein_heavy	DNAH9 DNAH11	3.68e-03	15	114	2	PF03028
Domain	PI3/4_kinase_CS	SMG1 ATR	3.68e-03	15	114	2	IPR018936
Domain	Dynein_heavy_dom	DNAH9 DNAH11	3.68e-03	15	114	2	IPR004273
Domain	-	SMG1 ATR	4.19e-03	16	114	2	1.10.1070.11
Domain	PI3Kc	SMG1 ATR	4.19e-03	16	114	2	SM00146
Domain	PI3_PI4_kinase	SMG1 ATR	5.30e-03	18	114	2	PF00454
Domain	PI3_4_KINASE_1	SMG1 ATR	5.30e-03	18	114	2	PS00915
Domain	PI3_4_KINASE_2	SMG1 ATR	5.30e-03	18	114	2	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 ATR	5.30e-03	18	114	2	IPR000403
Domain	PI3_4_KINASE_3	SMG1 ATR	5.30e-03	18	114	2	PS50290
Domain	Kinase-like_dom	SMG1 EPHA6 ATR KALRN CAMK4 MAP3K1 NEK1 BTK KIT	5.98e-03	542	114	9	IPR011009
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SLC4A7 FLVCR1 TBC1D24 SLC38A1 ESYT2 NF1 MICAL2 SLC20A2 GPSM2 DIAPH3 SLITRK6 VPS51 ARHGAP21	7.63e-08	569	118	13	30639242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CYLD MTMR12 URB2 SLC25A25 OPA1 GGA3 FOCAD UNC5A SRGAP3 LRRTM2 ARHGAP21	1.54e-07	407	118	11	12693553
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	GBF1 RNF213 OPA1 ESYT2 NF1 TARBP1	1.55e-06	104	118	6	31240132
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CYLD RAP1GAP COPA MYO5A KALRN ZFC3H1 INTS8 FAF1 FOCAD ODF2L SACS MICAL2 CIAO2B GPSM2 TARBP1 ARHGAP21 NR1D2	1.66e-06	1285	118	17	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RAP1GAP PDE4D COPA MYO5A KALRN GABARAPL2 DDB1 OPA1 TBC1D24 HSPA12A NF1 SACS SRGAP3 MICAL2 VPS51 ARHGAP21 DNAH11	6.93e-06	1431	118	17	37142655
Pubmed	Tissue and zonal-specific expression of an olfactory receptor transgene.	OR10H4 OR10H3	1.14e-05	2	118	2	9412503
Pubmed	Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.	NF1 KIT	1.14e-05	2	118	2	18984156
Pubmed	Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.	NF1 KIT	1.14e-05	2	118	2	12393498
Pubmed	Burkholderia pseudomallei interferes with host lipid metabolism via NR1D2-mediated PNPLA2/ATGL suppression to block autophagy-dependent inhibition of infection.	PNPLA2 NR1D2	1.14e-05	2	118	2	32777979
Pubmed	Transcription directed by human core promoters with a HomolD box sequence requires DDB1, RECQL and RNA polymerase II machinery.	RECQL DDB1	1.14e-05	2	118	2	22705827
Pubmed	Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.	TICRR ATR CIAO2B	2.99e-05	18	118	3	28191891
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	SMG1 HSPA12A SRGAP3 LRRTM2	3.01e-05	52	118	4	9455477
Pubmed	Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.	NF1 KIT	3.42e-05	3	118	2	10620616
Pubmed	Rab18 regulates lipolysis via Arf/GBF1 and adipose triglyceride lipase.	PNPLA2 GBF1	3.42e-05	3	118	2	31610914
Pubmed	Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.	NF1 KIT	3.42e-05	3	118	2	28296713
Pubmed	Quantitative trait loci influencing morphine antinociception in four mapping populations.	MYO5A OPRK1	3.42e-05	3	118	2	11420618
Pubmed	Neurofibromin as a regulator of melanocyte development and differentiation.	NF1 KIT	3.42e-05	3	118	2	18089649
Pubmed	The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.	SMG1 ATR	3.42e-05	3	118	2	15279777
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	PDE4D MYO5A KALRN OPA1 NF1 SACS SRGAP3	5.12e-05	281	118	7	28706196
Pubmed	Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.	ATR NEK1	6.82e-05	4	118	2	28426283
Pubmed	Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.	PNPLA2 LIPA	6.82e-05	4	118	2	25086775
Pubmed	Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.	NF1 KIT	6.82e-05	4	118	2	21037083
Pubmed	Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.	NF1 KIT	6.82e-05	4	118	2	18768391
Pubmed	Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.	TICRR ATR	6.82e-05	4	118	2	23696651
Pubmed	Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.	DNAH9 DNAH11	6.82e-05	4	118	2	36140829
Pubmed	Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit.	BTK KIT	6.82e-05	4	118	2	16176929
Pubmed	Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model.	NF1 KIT	6.82e-05	4	118	2	26732977
Pubmed	Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity.	KCTD19 KIT	6.82e-05	4	118	2	36845001
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	SLC4A7 FLVCR1 OPA1 TBC1D24 SLC38A1 ESYT2 HSPA12A ARHGAP21	9.90e-05	421	118	8	36976175
Pubmed	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.	SMG1 ATR NF1	1.05e-04	27	118	3	23027611
Pubmed	Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains.	GGA3 M6PR	1.13e-04	5	118	2	11859375
Pubmed	Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1.	PNPLA2 GBF1	1.13e-04	5	118	2	21789191
Pubmed	Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin.	TICRR ATR	1.13e-04	5	118	2	28439015
Pubmed	Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.	BTK KIT	1.13e-04	5	118	2	15007095
Pubmed	Structural insights into Fe-S protein biogenesis by the CIA targeting complex.	PRIM2 CIAO2B	1.13e-04	5	118	2	32632277
Pubmed	Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors.	GGA3 M6PR	1.13e-04	5	118	2	24407285
Pubmed	NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response.	ATR NEK1	1.13e-04	5	118	2	15604234
Pubmed	DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.	DNAH9 DNAH11	1.13e-04	5	118	2	26909801
Pubmed	HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA.	HSPA12A M6PR	1.13e-04	5	118	2	30679749
Pubmed	Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling.	ATR NEK1	1.13e-04	5	118	2	23345434
Pubmed	The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway.	ATR DDB1	1.13e-04	5	118	2	24045107
Pubmed	Sorting of mannose 6-phosphate receptors mediated by the GGAs.	GGA3 M6PR	1.13e-04	5	118	2	11387475
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CYLD SMG1 CUX2 GBF1 ESYT2 SRGAP3	1.24e-04	225	118	6	12168954
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CYLD SLC4A7 MYO5A KALRN CAMK4 OPA1 TBC1D24 ESYT2 HSPA12A NF1 SRGAP3 AKR7A3 VPS51	1.35e-04	1139	118	13	36417873
Pubmed	MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival.	DDB1 MAP3K1	1.70e-04	6	118	2	34251884
Pubmed	CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.	DNAH9 DNAH11	1.70e-04	6	118	2	33347437
Pubmed	Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.	FLVCR1 OPA1	1.70e-04	6	118	2	37100056
Pubmed	Association of gene polymorphisms with chronic kidney disease in high- or low-risk subjects defined by conventional risk factors.	PDE4D CETP	1.70e-04	6	118	2	19424605
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ATR COPA INTS8 DDB1 FAF1 HSPA12A NF1 DIAPH3 VPS51	1.72e-04	582	118	9	20467437
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD MTMR12 RAP1GAP SLC4A7 GBF1 NCKAP5L FSIP2 NEK1 ESYT2 NF1 ARHGAP21	1.74e-04	861	118	11	36931259
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	COPA RNF213 DDB1 OPA1 FOCAD ESYT2 CIAO2B	1.80e-04	344	118	7	36282215
Pubmed	HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing.	ATR DDB1	2.37e-04	7	118	2	20008788
Pubmed	HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.	ATR DDB1	2.37e-04	7	118	2	19798433
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH9 DNAH11	2.37e-04	7	118	2	31178125
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CYLD GBF1 MYO5A RNF213 RECQL GABARAPL2 FAF1 GGA3	2.45e-04	481	118	8	28190767
Pubmed	The DNA sequence and analysis of human chromosome 13.	SACS MPHOSPH8 DIAPH3 SLITRK6 PCDH9	2.95e-04	170	118	5	15057823
Pubmed	HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.	ATR KIT	3.15e-04	8	118	2	23039116
Pubmed	Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum.	DIAPH3 PCDH9	3.15e-04	8	118	2	22666227
Pubmed	A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.	SLC4A7 MAP3K1	3.15e-04	8	118	2	24493630
Pubmed	Mouse minipuberty coincides with gonocyte transformation into spermatogonial stem cells: a model for human minipuberty.	LHCGR KIT	3.15e-04	8	118	2	28531375
Pubmed	Genetically determined murine models of immunodeficiency.	BTK KIT	3.15e-04	8	118	2	3297105
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	SMG1 ATR	3.15e-04	8	118	2	20810650
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CYLD SLC4A7 CAMK4 FLVCR1 RNF213 PKHD1L1 SLC38A1 AP4E1 PCDH9 ARHGAP21	3.26e-04	777	118	10	35844135
Pubmed	Vpr-induced DNA double-strand breaks: molecular mechanism and biological relevance.	ATR DDB1	4.05e-04	9	118	2	19275579
Pubmed	Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.	NF1 KIT	4.05e-04	9	118	2	26460546
Pubmed	The human RNA surveillance factor UPF1 is required for S phase progression and genome stability.	SMG1 ATR	4.05e-04	9	118	2	16488880
Pubmed	Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2.	CYLD DDB1	4.05e-04	9	118	2	28035050
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA12 ABCA9	5.05e-04	10	118	2	11435397
Pubmed	HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.	ATR DDB1	5.05e-04	10	118	2	18514189
Pubmed	The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.	ATR DDB1	5.05e-04	10	118	2	20347598
Pubmed	Insights into COPI coat assembly and function in living cells.	GBF1 COPA	5.05e-04	10	118	2	16956762
Pubmed	Common genetic variants associated with breast cancer and mammographic density measures that predict disease.	SLC4A7 MAP3K1	5.05e-04	10	118	2	20145138
Pubmed	TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry.	KIT TANGO6	5.05e-04	10	118	2	38490996
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	SMG1 ATR	5.05e-04	10	118	2	18160036
Pubmed	IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway.	PRIM2 CIAO2B	5.05e-04	10	118	2	23585563
Pubmed	Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.	ATR MAP3K1	5.05e-04	10	118	2	37592023
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	SMG1 CCDC60 GBF1 NF1 RASGEF1B CES4A KIT	5.95e-04	420	118	7	28065597
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	SMG1 ATR	6.15e-04	11	118	2	20427287
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	PDE4D GBF1 ATR COPA MYO5A	6.47e-04	202	118	5	33005030
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	KALRN SRGAP3 BTK	6.64e-04	50	118	3	19807924
Pubmed	Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins.	BTK KIT	7.37e-04	12	118	2	10872802
Pubmed	Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.	CHL1 NF1	7.37e-04	12	118	2	22789544
Pubmed	WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.	PDE4D HSPA12A NF1	7.45e-04	52	118	3	30655611
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SMG1 GABARAPL2 URB2 INTS8 C2CD2 PRIM2 VPS51 TARBP1 ARHGAP21	7.93e-04	719	118	9	35337019
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ATR COPA RNF213 ALG11 RECQL DDB1 SLC38A1 NF1 MICAL2 M6PR ARHGAP21 TANGO6	8.05e-04	1201	118	12	35696571
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MTMR12 COPA MYO5A FLVCR1 RNF213 NCKAP5L OPA1 SLC38A1 ESYT2 HSPA12A PRIM2	9.06e-04	1049	118	11	27880917
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	SLC4A7 FLVCR1 NF1 BTK	9.44e-04	127	118	4	30442766
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PNPLA2 GBF1 ATR RNF213 ALG11 GABARAPL2 INTS8 C2CD2 FOCAD NF1 PCDH9	9.93e-04	1061	118	11	33845483
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	MYO5A KIT	1.01e-03	14	118	2	19320733
Pubmed	MEIOB targets single-strand DNA and is necessary for meiotic recombination.	ATR KIT	1.01e-03	14	118	2	24068956
Pubmed	Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.	CUX2 PCDH9	1.01e-03	14	118	2	20847152
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SMG1 ATR SLC25A25 MAP3K1 LHCGR NEK1 NF1 BTK VPS51 ARHGAP21	1.10e-03	910	118	10	36736316
Pubmed	MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.	PRIM2 CIAO2B	1.16e-03	15	118	2	22678361
Pubmed	SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.	CUX2 DIAPH3	1.16e-03	15	118	2	18215621
Pubmed	CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.	SMG1 ATR	1.16e-03	15	118	2	20864032
Pubmed	HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes.	ATR KIT	1.16e-03	15	118	2	22530760
Pubmed	Genetic mutations associated with cigarette smoking in pancreatic cancer.	ATR NF1 KIT	1.30e-03	63	118	3	19351817
Pubmed	Structure-function relationship of Vpr: biological implications.	ATR DDB1	1.33e-03	16	118	2	19275588
Pubmed	Linkage analyses using biochemical variants in mice. 3. Linkage relationships of eleven biochemical markers.	MYO5A KIT	1.33e-03	16	118	2	5424503
Pubmed	Dual role of Fam208a during zygotic cleavage and early embryonic development.	GPSM2 MPHOSPH8	1.33e-03	16	118	2	34216590
Interaction	HRAS interactions	PDE4D SLC4A7 GBF1 FLVCR1 TBC1D24 SLC38A1 HSPA12A NF1 MICAL2 SLC20A2 BTK GPSM2 DIAPH3 SLITRK6 C9orf72 VPS51 PCDH9 ARHGAP21	1.14e-07	725	113	18	int:HRAS
Interaction	OPALIN interactions	SLC4A7 ATR SLC39A3 FLVCR1 RNF213 URB2 INTS8 NF1 VPS51 TARBP1	2.85e-07	209	113	10	int:OPALIN
Interaction	MGARP interactions	GBF1 ATR RNF213 URB2 SLC25A25 INTS8 C2CD2 HSPA12A C9orf72 VPS51	4.96e-07	222	113	10	int:MGARP
Interaction	GYPA interactions	SMG1 GBF1 ATR CAMK4 URB2 FOCAD NF1 DIAPH3 TARBP1	5.99e-07	174	113	9	int:GYPA
Interaction	NPTN interactions	SMG1 GBF1 ATR RNF213 INTS8 OPA1 FOCAD HSPA12A VPS51 TARBP1	3.78e-06	278	113	10	int:NPTN
Interaction	ZFPL1 interactions	SLC4A7 GBF1 COPA FLVCR1 FAF1 GGA3 SLC38A1 AP4E1 ESYT2 SLC20A2 VPS51 ARHGAP21	8.18e-06	448	113	12	int:ZFPL1
Interaction	SCN2B interactions	ATR RNF213 OPA1 FOCAD DIAPH3 TARBP1	1.58e-05	95	113	6	int:SCN2B
Interaction	HCST interactions	GBF1 ATR RNF213 ALG11 INTS8 FOCAD NF1 TARBP1	2.05e-05	205	113	8	int:HCST
Interaction	RHOF interactions	SLC4A7 GBF1 ATR MYO5A FLVCR1 NCKAP5L C2CD2 SLC38A1 ESYT2 HSPA12A SLC20A2 DIAPH3 VPS51 ARHGAP21	2.43e-05	673	113	14	int:RHOF
Interaction	ARF1 interactions	GBF1 SLC39A3 GGA3 SLC38A1 AP4E1 PLEKHG6 C9orf72 VPS51 ARHGAP21	3.04e-05	282	113	9	int:ARF1
Interaction	RHOQ interactions	SLC4A7 MYO5A FLVCR1 SLC38A1 ESYT2 NF1 SLC20A2 DIAPH3 C9orf72 VPS51 ARHGAP21	3.89e-05	442	113	11	int:RHOQ
Interaction	C3orf18 interactions	SMG1 ATR NF1 SACS DIAPH3 TARBP1	4.66e-05	115	113	6	int:C3orf18
Interaction	GPR182 interactions	GBF1 ATR RNF213 URB2 SLC25A25 INTS8 C2CD2 FOCAD ESYT2 VPS51 TARBP1	5.06e-05	455	113	11	int:GPR182
Interaction	EBAG9 interactions	SLC4A7 GBF1 COPA GGA3 SLC38A1 ESYT2 HSPA12A DIAPH3 VPS51	5.30e-05	303	113	9	int:EBAG9
Interaction	HLA-B interactions	GBF1 ATR SLC39A3 RNF213 RECQL INTS8 C9orf72 VPS51	6.11e-05	239	113	8	int:HLA-B
Interaction	TMEM17 interactions	SLC4A7 COPA FLVCR1 GGA3 SLC38A1 AP4E1 ESYT2 HSPA12A SLC20A2 VPS51	9.29e-05	404	113	10	int:TMEM17
Interaction	GJA1 interactions	SLC4A7 GBF1 COPA KALRN FLVCR1 GGA3 SLC38A1 AP4E1 ESYT2 VPS51 PCDH9 ARHGAP21	1.06e-04	583	113	12	int:GJA1
Cytoband	16q22.1	KCTD19 GABARAPL2 CIAO2B CES4A TANGO6	1.02e-05	110	118	5	16q22.1
Cytoband	19p13.1	OR10H3 OR10H2 OR10H1	2.63e-04	48	118	3	19p13.1
GeneFamily	Olfactory receptors, family 10	OR10H5 OR10H4 OR10H3 OR10H2 OR10H1	8.96e-06	66	77	5	157
GeneFamily	Lipases\|Arylacetamide deacetylase family	PNPLA2 LIPF LIPA	1.08e-04	22	77	3	464
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM2 MAP3K1	6.32e-04	9	77	2	90
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	TAGAP SRGAP3 ARHGAP21	1.26e-03	50	77	3	721
GeneFamily	ATP binding cassette subfamily A	ABCA12 ABCA9	1.58e-03	14	77	2	805
GeneFamily	Dyneins, axonemal	DNAH9 DNAH11	2.34e-03	17	77	2	536
Coexpression	FIRESTEIN_PROLIFERATION	CYLD TICRR EPHA6 ATR KALRN CAMK4 NF1 BTK	7.77e-07	166	116	8	M5354
Coexpression	DODD_NASOPHARYNGEAL_CARCINOMA_UP	SMG1 TICRR ATR FLVCR1 RNF213 RECQL URB2 THUMPD2 INTS8 CD163 TBC1D24 NF1 SACS MICAL2 PRIM2 PIGW GPSM2 DIAPH3 TARBP1	1.30e-05	1407	116	19	M14427
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYLD CUX2 PDE4D CAMK4 SLC38A1 ODF2L SACS	3.19e-07	167	118	7	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYLD SMG1 SLC4A7 CAMK4 RNF213 ZFC3H1 PARP15	9.70e-07	197	118	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC60 CCDC81 OPRK1 HEATR9 DNAH9 DNAH11	3.64e-06	155	118	6	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC60 CCDC81 OPRK1 HEATR9 DNAH9 DNAH11	3.64e-06	155	118	6	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO5A ZFC3H1 ABCA9 CD163 MAP3K1	6.84e-06	173	118	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO5A ZFC3H1 ABCA9 CD163 MAP3K1	6.84e-06	173	118	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO5A ZFC3H1 ABCA9 CD163 MAP3K1	6.84e-06	173	118	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CCDC60 CCDC81 SRGAP3 SLITRK6 DNAH9 DNAH11	9.13e-06	182	118	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D MYO5A UGT3A1 SLC38A1 ESYT2 SLC20A2	1.00e-05	185	118	6	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP LHCGR HSPA12A DIAPH3 PCDH9	1.03e-05	186	118	6	adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A GPSM2 DIAPH3 SLITRK6	1.07e-05	187	118	6	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A GPSM2 DIAPH3 SLITRK6	1.07e-05	187	118	6	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 GNE MAP3K1 SRGAP3 DIAPH3 DNAH11	1.10e-05	188	118	6	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D MYO5A UGT3A1 SLC38A1 ESYT2 SRGAP3	1.13e-05	189	118	6	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D MYO5A UGT3A1 SLC38A1 ESYT2 KIT	1.13e-05	189	118	6	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	background-B_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CYP2E1 TAGAP SLC38A1 RASGEF1B PCDH9 PARP15	1.20e-05	191	118	6	a189fdc9c739bb0801e2f38af0932a1ea615cb34
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CHL1 CCDC60 SRGAP3 CES4A DNAH9 DNAH11	1.27e-05	193	118	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 GNE MAP3K1 SRGAP3 DIAPH3 PCDH9	1.27e-05	193	118	6	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 GNE MAP3K1 SRGAP3 DIAPH3 PCDH9	1.27e-05	193	118	6	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 GNE MAP3K1 SRGAP3 DIAPH3 PCDH9	1.27e-05	193	118	6	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4D SLC4A7 TOMM5 SLC38A1 SACS PARP15	1.39e-05	196	118	6	fd756b247b2d8a291e8e71bec6f1e463d6557536
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KALRN PKHD1L1 SLC38A1 SRGAP3 MICAL2 GPSM2	1.39e-05	196	118	6	b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KALRN PKHD1L1 SLC38A1 SRGAP3 MICAL2 GPSM2	1.39e-05	196	118	6	a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC81 AK9 ODF2L HSPA12A DNAH9 DNAH11	1.43e-05	197	118	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 SLC4A7 RNF213 ZFC3H1 ODF2L PARP15	1.52e-05	199	118	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PDE4D CAMK4 RNF213 SLC38A1 ODF2L NR1D2	1.52e-05	199	118	6	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	KALRN FOCAD ODF2L MICAL2 TARBP1 DPY19L2P1	1.56e-05	200	118	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 PDE4D RNF213 SLC38A1 ODF2L PARP15	1.56e-05	200	118	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	CHL1 MYO5A SLC38A1 NF1 SRGAP3 ARHGAP21	1.56e-05	200	118	6	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA12 OPRK1 PLEKHG6 BNIPL DIAPH3	4.10e-05	144	118	5	f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK4 ZSWIM2 CES4A DNAH9 DNAH11	6.56e-05	159	118	5	00a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPHA6 TRPM2 CD163 SLC20A2 M6PR	6.76e-05	160	118	5	5d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAF1 SRGAP3 BNIPL SLITRK6 NR1D2	6.76e-05	160	118	5	445cef1f2f3279672620664792d4eec54df71bdb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR KCTD19 PRIM2 GPSM2 DIAPH3	8.28e-05	167	118	5	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SLC38A1 ODF2L SRGAP3 KIT PCDH9	8.28e-05	167	118	5	94642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SLC38A1 ODF2L SRGAP3 KIT PCDH9	8.28e-05	167	118	5	42b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SLC38A1 ODF2L SRGAP3 KIT PCDH9	8.28e-05	167	118	5	ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR TAGAP CAMK4 FLVCR1 TARBP1	8.51e-05	168	118	5	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-Th17\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE4D CAMK4 ODF2L KIT TANGO6	8.51e-05	168	118	5	97bf074b91c9ae0064edc31fa4a2658ffdcfefa3
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AK9 SRGAP3 SLITRK6 DNAH9 DNAH11	8.75e-05	169	118	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AK9 ODF2L CES4A DNAH9 DNAH11	8.75e-05	169	118	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 MAP3K1 FSIP2 SRGAP3 DNAH11	9.00e-05	170	118	5	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CYLD PDE4D SLC4A7 SLC38A1 ODF2L	9.25e-05	171	118	5	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	PND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYO5A TAGAP ABCA9 CD163 PRIM2	9.51e-05	172	118	5	9a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell	Control-CD4+_T_activated\|World / Disease group and Cell class	GNE BTK RASGEF1B LRP5L NR1D2	9.77e-05	173	118	5	12f8e4276b290bb388a56de4c8d8dd60415b2f63
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 MYO5A RNF213 CD163 LIPA	1.00e-04	174	118	5	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP CD163 SLC38A1 BTK KIT	1.00e-04	174	118	5	773329bb91b97578df138446cf62101dd0dad758
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR BAHD1 C2CD2 DIAPH3 TANGO6	1.00e-04	174	118	5	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR ODF2L MICAL2 GSTCD DIAPH3	1.00e-04	174	118	5	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN CHRAC1 PKHD1L1 SRGAP3 PIGW	1.03e-04	175	118	5	9a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN CHRAC1 PKHD1L1 SRGAP3 PIGW	1.03e-04	175	118	5	54c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO5A ZFC3H1 ABCA9 MAP3K1	1.03e-04	175	118	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN CHRAC1 PKHD1L1 SRGAP3 PIGW	1.03e-04	175	118	5	2b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A PLEKHG6 PCDH9	1.12e-04	178	118	5	ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCell	Control-T/NK-NK\|Control / Disease group,lineage and cell class （2021.01.30）	SLC38A1 ODF2L SRGAP3 KIT PCDH9	1.12e-04	178	118	5	079fd19bdeed86bf985c4083af432432d66ad546
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A7 MAP3K1 BTK RASGEF1B C9orf72	1.15e-04	179	118	5	f4fd214a9865c635d8a744ce5e0eff45174d3de4
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A7 MAP3K1 BTK RASGEF1B C9orf72	1.15e-04	179	118	5	57d8d44a793314eec8f77030f4177bfe21d41652
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 HSPA12A LRRTM2 DIAPH3 SLITRK6	1.15e-04	179	118	5	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYP2E1 SRGAP3 DIAPH3 KIT DNAH11	1.15e-04	179	118	5	140dd7dbac48f5f07279f31bf971d7fbd41fa18b
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TAGAP SLC38A1 BTK PCDH9 PARP15	1.21e-04	181	118	5	57f20341c3e9f9f6ed5b6c181605ad35bae91414
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A LRRTM2 PCDH9	1.24e-04	182	118	5	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ZSWIM2 PKHD1L1 UNC5A MICAL2	1.24e-04	182	118	5	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ZSWIM2 PKHD1L1 UNC5A MICAL2	1.24e-04	182	118	5	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A LRRTM2 PCDH9	1.24e-04	182	118	5	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ZSWIM2 PKHD1L1 UNC5A MICAL2	1.24e-04	182	118	5	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A LRRTM2 GPSM2	1.24e-04	182	118	5	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	Adult-Epithelial-basal_cell\|Adult / Lineage, Cell type, age group and donor	CHL1 CCDC60 CUX2 SRGAP3 SLITRK6	1.27e-04	183	118	5	00a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA12 PKHD1L1 DNAH9 DNAH11	1.30e-04	184	118	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	MYO5A ABCA9 NEK1 KIT PCDH9	1.30e-04	184	118	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	CYP2E1 ODF2L SRGAP3 KIT PCDH9	1.30e-04	184	118	5	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP MAP3K1 SLC38A1 BTK RASGEF1B	1.30e-04	184	118	5	5cf7447faaec99fc37dfa8e92ff72cc2c7c05951
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP MAP3K1 SLC38A1 BTK RASGEF1B	1.30e-04	184	118	5	7126261a453c7e2f3f005016873b6adeb51e46f8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA12 PKHD1L1 DNAH9 DNAH11	1.30e-04	184	118	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SMG1 PDE4D SLC4A7 ODF2L RASGEF1B	1.30e-04	184	118	5	cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ABCA12 PKHD1L1 DNAH9 DNAH11	1.30e-04	184	118	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MTMR12 GGA3 DIAPH3 LRP5L KIT	1.30e-04	184	118	5	b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP HSPA12A LRRTM2 SLITRK6	1.30e-04	184	118	5	9f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MTMR12 SLC4A7 KALRN ESYT2 KIT	1.34e-04	185	118	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CETP PKHD1L1 SLC38A1 UNC5A MICAL2	1.34e-04	185	118	5	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	MTMR12 GGA3 DIAPH3 LRP5L KIT	1.34e-04	185	118	5	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CETP PKHD1L1 SLC38A1 UNC5A MICAL2	1.34e-04	185	118	5	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	(1)_B_CD27neg\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	TAGAP PKHD1L1 BTK PCDH9 PARP15	1.37e-04	186	118	5	646389147189760e9493c4f50f9583959ef0ee26
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CCDC60 CETP SLC38A1 UNC5A MICAL2	1.37e-04	186	118	5	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CCDC60 CETP SLC38A1 UNC5A MICAL2	1.37e-04	186	118	5	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 RAP1GAP LRRTM2 DIAPH3 SLITRK6	1.41e-04	187	118	5	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MTMR12 GBF1 RNF213 INTS8 MICAL2	1.41e-04	187	118	5	689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MTMR12 GBF1 RNF213 INTS8 MICAL2	1.41e-04	187	118	5	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 EPHA6 MAP3K1 SRGAP3 DIAPH3	1.41e-04	187	118	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 PDE4D KALRN MICAL2 DPY19L2P1	1.44e-04	188	118	5	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	background-B_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	TAGAP MAP3K1 SLC38A1 PCDH9 PARP15	1.44e-04	188	118	5	9acb7a95e3095f15918a5d094107d1d565a42842
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	PDE4D SLC38A1 DIAPH3 KIT DNAH9	1.44e-04	188	118	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 SLC4A7 EPHA6 SLC20A2 PCDH9	1.48e-04	189	118	5	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GNE MAP3K1 SRGAP3 DIAPH3 DNAH11	1.48e-04	189	118	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	CAMK4 ALG11 SLC38A1 ODF2L GPSM2	1.48e-04	189	118	5	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 KALRN FOCAD MICAL2 DPY19L2P1	1.48e-04	189	118	5	c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 EPHA6 MAP3K1 SRGAP3 DIAPH3	1.52e-04	190	118	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYLD PDE4D CAMK4 SLC38A1 ODF2L	1.52e-04	190	118	5	55df73c8b696967a925b1772631f6900eff0fa30
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TAGAP TRPM2 CD163 BTK PARP15	1.52e-04	190	118	5	e5625feb21915d4545cfad2659745ef180efcb1f
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	MTMR12 PRIM2 LRP5L NR1D2 PARP15	1.52e-04	190	118	5	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDE4D TAGAP SLC38A1 SACS PARP15	1.52e-04	190	118	5	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
Disease	Large cell carcinoma of lung	ATR CAMK4 NEK1 BTK	6.99e-06	32	114	4	C0345958
Disease	C-reactive protein measurement	CCDC60 PGS1 CUX2 RAP1GAP GLS2 CETP GPRC6A MAP3K1 SLC38A1 LHCGR HSPA12A LIPA SLITRK6 KIT ARHGAP21 DNAH11	1.64e-05	1206	114	16	EFO_0004458
Disease	blood osmolality measurement	CUX2 ABCA12 SLITRK6 CYB5R4	7.63e-05	58	114	4	EFO_0007967
Disease	Malignant neoplasm of breast	RAP1GAP KALRN RECQL MAP3K1 GGA3 LHCGR NF1 SRGAP3 BTK HEATR9 CYB5R4 KIT DNAH9	2.65e-04	1074	114	13	C0006142
Disease	mean reticulocyte volume	PGS1 RAP1GAP ATR URB2 CHRAC1 BAHD1 FAF1 TBC1D24 MINDY3 CC2D2A ARHGAP21	2.75e-04	799	114	11	EFO_0010701
Disease	atrioventricular septal defect (implicated_via_orthology)	NR1D2 DNAH11	3.07e-04	7	114	2	DOID:0050651 (implicated_via_orthology)
Disease	Thymic Carcinoma	CYLD KIT	3.07e-04	7	114	2	C0205969
Disease	mean corpuscular hemoglobin concentration	TICRR PGS1 CUX2 GLS2 ATR KALRN URB2 INTS8 FOCAD SLC38A1 SLC20A2 CC2D2A ARHGAP21	3.48e-04	1105	114	13	EFO_0004528
Disease	lipoprotein-associated phospholipase A(2) measurement	CETP RNF213 TOMM5	5.00e-04	40	114	3	EFO_0004746
Disease	lifestyle measurement, systolic blood pressure	KALRN OPRK1	5.23e-04	9	114	2	EFO_0006335, EFO_0010724
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	PGS1 CETP SLC38A1 DNAH11	6.71e-04	102	114	4	EFO_0004329, EFO_0004611
Disease	potassium measurement	SLC4A7 AP4E1 PCDH9	7.08e-04	45	114	3	EFO_0009283
Disease	granulosa cell tumor (is_marker_for)	LHCGR KIT	7.95e-04	11	114	2	DOID:2999 (is_marker_for)
Disease	lipoprotein A measurement	PGS1 GLS2 TAGAP CETP	9.52e-04	112	114	4	EFO_0006925
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	PGS1 GBF1 CETP FAF1 SLC38A1	1.10e-03	200	114	5	EFO_0004611, EFO_0020945
Disease	non-high density lipoprotein cholesterol measurement	PGS1 CETP ABCA9 CD163 SLC38A1 ESYT2 LIPA M6PR DNAH11	1.82e-03	713	114	9	EFO_0005689
Disease	Moyamoya Disease	RNF213 NF1	1.94e-03	17	114	2	C0026654
Disease	Familial Progressive Myoclonic Epilepsy	TBC1D24 SACS	1.94e-03	17	114	2	C0751777
Disease	Atypical Inclusion-Body Disease	TBC1D24 SACS	1.94e-03	17	114	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	TBC1D24 SACS	1.94e-03	17	114	2	C0751778
Disease	Biotin-Responsive Encephalopathy	TBC1D24 SACS	1.94e-03	17	114	2	C0751780
Disease	May-White Syndrome	TBC1D24 SACS	1.94e-03	17	114	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	TBC1D24 SACS	1.94e-03	17	114	2	C0751781
Disease	Profound Mental Retardation	CHL1 AP4E1 NF1 SRGAP3	2.11e-03	139	114	4	C0020796
Disease	Mental Retardation, Psychosocial	CHL1 AP4E1 NF1 SRGAP3	2.11e-03	139	114	4	C0025363
Disease	Mental deficiency	CHL1 AP4E1 NF1 SRGAP3	2.11e-03	139	114	4	C0917816
Disease	Action Myoclonus-Renal Failure Syndrome	TBC1D24 SACS	2.17e-03	18	114	2	C0751779
Disease	Chronic myeloproliferative disorder	ATR KIT	2.42e-03	19	114	2	C1292778
Disease	sensorineural hearing loss (implicated_via_orthology)	SLITRK6 DNAH9	2.42e-03	19	114	2	DOID:10003 (implicated_via_orthology)
Disease	myocardial infarction	CUX2 KALRN SLC38A1 LIPA PRIM2 RASGEF1B	2.43e-03	350	114	6	EFO_0000612
Disease	Nonorganic psychosis	SLC39A3 TRPM2 C9orf72	2.44e-03	69	114	3	C0349204
Disease	aspartate aminotransferase measurement	PGS1 CUX2 SLC4A7 KALRN CETP RNF213 CD163 HSPA12A LIPA NF1	2.68e-03	904	114	10	EFO_0004736
Disease	sleep duration	PDE4D GBF1 TRPM2 NEK1 SRGAP3 RASGEF1B	2.87e-03	362	114	6	EFO_0005271
Disease	Infiltrating duct carcinoma of female breast	SMG1 ATR	2.96e-03	21	114	2	C3165106
Disease	Dyslipidemias	CETP DNAH11	3.86e-03	24	114	2	C0242339
Disease	Dyslipoproteinemias	CETP DNAH11	3.86e-03	24	114	2	C0598784

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLSLVLNFRKITAFL	URB2	1016	Q14146
PQDRQFILSSKKLLL	TRBV30	86	A0A0K0K1B3
AFITRNPFLSKVKLI	ALG11	221	Q2TAA5
ALSIFFLRKPLLEIN	ESYT2	316	A0FGR8
KLFLSLLDFQITPKT	CETP	396	P11597
LKPDSLRFQLETSLK	AKR7A3	86	O95154
SPLNFKKRLFLLTVH	BTK	21	Q06187
VRPLSQAFFKLEIVK	ABCA9	1561	Q8IUA7
ISETLKRIFLIFPQF	ABCA12	2136	Q86UK0
PKSFLEQISLFKNLL	DNAH11	3071	Q96DT5
LRPRLSAILFKLQFE	DIAPH3	796	Q9NSV4
LIAKEAFFPTQKFLL	CUX2	396	O14529
FSVNLSLLDFIRPLK	AP4E1	1021	Q9UPM8
FDLLSKLPEDLKNFR	CCDC60	456	Q8IWA6
LLLPLFKDTIEKINF	ODF2L	66	Q9ULJ1
FQLELKNIPKSFTRL	CYP2E1	46	P05181
LFLRPNKEKIDFLLE	INTS8	406	Q75QN2
FLRLGKLFLPSEFKE	KCTD19	451	Q17RG1
KQIKDRVILLFSPIS	OR52Z1P	281	P0C646
PSFNLVKIIRSFLLK	PNPLA2	86	Q96AD5
VKIIRSFLLKVLPAD	PNPLA2	91	Q96AD5
LKVVAKTLLDPFQFV	DPY19L2P1	66	Q6NXN4
PVQAFLLKKLLFSSE	MINDY3	56	Q9H8M7
LSPIIFSLRNKELKV	OR10H5	286	Q8NGA6
LSPIIFSLRNKELKV	OR10H2	286	O60403
SLQFPKAVFAKLILS	PARP15	211	Q460N3
LKELILSSNKIFYLP	LRRTM2	111	O43300
LIAKPSAKLLFVNRL	GPSM2	436	P81274
LKKLPSRETFVNLLE	LHCGR	256	P22888
GFIAKRIEKFLSPQL	NEK1	256	Q96PY6
FLLLKFSKAIEIPSS	CHL1	16	O00533
ALDALSPFLRKKAQI	NCKAP5L	176	Q9HCH0
LSEKFILKVRPAFKA	KIT	196	P10721
HTQAPKLLKRLFLFS	MTMR12	171	Q9C0I1
IVLDPKKRLTTFQAL	CAMK4	281	Q16566
VKAFLALLRPFISSK	BNIPL	301	Q7Z465
EIAVKFLSKLLSIFP	FSIP2	6181	Q5CZC0
INKLRFVPQSLFKFI	LIPF	211	P07098
VILPNDFFRLIKIKI	PCDH9	116	Q9HC56
AKFPSNLKVSILLDF	PGS1	151	Q32NB8
TIFQERDLLKTFKIP	PDE4D	426	Q08499
LFRLFITSNPLKVAK	CES4A	251	Q5XG92
TLSDFLIKPIQRITK	KALRN	2051	O60229
QTLLKDKLPHIFRFT	LRP5L	156	A4QPB2
QKRKELLLSSLKPFS	FAM161B	246	Q96MY7
KFRFLNELIKVVSPK	GGA3	86	Q9NZ52
IVLLTQAFRKKFVIP	GLS2	141	Q9UI32
LFQKPEVSTVKFLFL	HSPA12A	466	O43301
REKIVIPFFSLLIKD	RASGEF1B	366	Q0VAM2
FLSPIIFSLRNKELK	OR10H3	286	O60404
FLSPIIFSLRNKELK	OR10H4	286	Q8NGA5
SLKILLAFSFDPKLQ	GPRC6A	681	Q5T6X5
DLLRFRFSILPKDKI	PRIM2	126	P49643
RFSILPKDKIQDFLK	PRIM2	131	P49643
QFSSLTNLPLRKLKF	OPA1	61	O60313
FLFSDVLLVTKPQRK	PLEKHG6	431	Q3KR16
ALSEKLKVFREFLLP	ATR	2416	Q13535
ILGLSLFKLAEQKRP	CC2D2A	1006	Q9P2K1
LLATATVPLDLFKKQ	C2CD2	341	Q9Y426
AVPRILKFLKSIDLQ	GNE	366	Q9Y223
LFPAKVTNVSLLEKF	CCDC81	266	Q6ZN84
TIDPTEFKFKLALIN	COPA	591	P53621
PKRLASLNAAAFLKL	BAHD1	201	Q8TBE0
TLLFILTAIAFKEKP	FLVCR1	286	Q9Y5Y0
LFEELTKLLSKNAFP	GBF1	551	Q92538
KIDIRPFKASLLNII	DNAH9	1086	Q9NYC9
KSLLEVKLFPQETLF	FAF1	631	Q9UNN5
FKKIFPSLELNITDL	CYLD	766	Q9NQC7
LLAIFVALFFLTKKR	CD163	1061	Q86VB7
LFVLIRIFILKKEDP	SLC20A2	161	Q08357
LKKFLSFFPVNRLDL	SACS	2956	Q9NZJ4
ISRKFSEKLVEFPLL	GSTCD	301	Q8NEC7
LSIKVKLLRSLPQRF	CIAO2B	101	Q9Y3D0
LFRPKGESKDLLFIL	DDB1	66	Q16531
PFKSLRNLKIDLDLT	C9orf72	426	Q96LT7
LKATLLSLRVLPEFK	FOCAD	1776	Q5VW36
KRIQLPSEKAIFLFV	GABARAPL2	66	P60520
ALEKLLQPFKSTSLR	MICAL2	1701	O94851
LKEIRNAFDLFKLTP	MPHOSPH8	441	Q99549
LFIRLTEAPSAKVKL	MPHOSPH8	836	Q99549
LSPIIFSLRNKELKV	OR10H1	286	Q9Y4A9
PKFTDIVSFLDKLIR	EPHA6	921	Q9UF33
ALDFRTPLKAKIINI	OPRK1	166	P41145
FTKLLLKLPDLRSLN	NR1D2	551	Q14995
PVEIRYKKLLSLLTF	MAP3K1	786	Q13233
FELSVPSKEIFKRLL	AK9	1521	Q5TCS8
ILDIKRKAPFFLSDF	SLC4A7	586	Q9Y6M7
IEPSAFSKLNRLKVL	SLITRK6	151	Q9H5Y7
VVFKDFLRSIPRKLL	TAGAP	156	Q8N103
FLQLSKRPLVASEFL	IQCA1L	751	A6NCM1
EKLFIPSSKLLFLRY	SMG1	521	Q96Q15
RKGPEFQEFLLTKLI	RAP1GAP	356	P47736
LEQLILTFRKEKPSF	SLC39A3	101	Q9BRY0
SPALLSEFLKRNLDK	CYB5R4	471	Q7L1T6
RLPFLKILEKFLNIS	PIGW	106	Q7Z7B1
TFQFLADILPKKILA	CHRAC1	86	Q9NRG0
VFKLEKFRPLQLETI	RECQL	86	P46063
LPAELKSIFKLSVFI	SLC25A25	26	Q6KCM7
SPEKLLEKAFAIRLF	TBC1D24	281	Q9ULP9
FLQKEAELRLVKFLP	RNF213	4771	Q63HN8
KLQFLFELPSRLTKC	VPS51	176	Q9UID3
SFLIAEKLVKPFVAI	UGT3A1	151	Q6NUS8
LFNQELLSPSKRSLK	TICRR	916	Q7Z2Z1
LALVKRLKPLFNKSF	M6PR	46	P20645
LFPKERFQDLISTIK	SRGAP3	591	O43295
ALISNKPEFVKLFLE	TRPM2	491	O94759
FRLAKLNPLFIAKSI	HEATR9	511	A2RTY3
KSSDFAVLKQLLPLL	TANGO6	711	Q9C0B7
SAERLFLLIKKQFPL	THUMPD2	66	Q9BTF0
KQVLRLSLTEFSLPK	NF1	2146	P21359
ALLRVTPFILKKLDS	TOMM5	36	Q8N4H5
NLALFLKIPSDKIRI	PKHD1L1	3961	Q86WI1
SVAAAKRLKLLLFAP	UNC5A	586	Q6ZN44
SAFKIPFLIRQKIIS	UNC5A	751	Q6ZN44
FAPLKLILEEFKNSS	ZSWIM2	201	Q8NEG5
LRFQLAPIKKLEGSL	nan	56	Q6ZS52
LPEEIKSSFLLKFIR	TARBP1	461	Q13395
LNVISSLLKSFFRKL	ARHGAP21	1216	Q5T5U3
SLLKSFFRKLPEPLF	ARHGAP21	1221	Q5T5U3
FAILKESPRSLLAQK	ARHGAP21	1521	Q5T5U3
FQAFELKPLRQKLTL	ZFC3H1	296	O60293
LFIVKNELPSAIKFL	SLC38A1	166	Q9H2H9
NSAKVLILVLKRFPD	USP17L10	271	C9JJH3
FIAFSQIPELAKRIK	LIPA	181	P38571
ALFEKPRLSNKAFII	MYO5A	536	Q9Y4I1