Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enone reductase activity	SRD5A1 AKR1C1 AKR1C2	1.22e-05	8	122	3	GO:0035671
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP1A1 CYP27B1 AKR1C1 AKR1C2	1.02e-04	40	122	4	GO:0016709
GeneOntologyMolecularFunction	demethylase activity	CYP1A1 CYP1A2 KDM3A KDM3B	1.49e-04	44	122	4	GO:0032451
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	CYP1A1 CYP1A2 KDM3A CYP27B1 KDM3B AKR1C1 AKR1C2	1.92e-04	194	122	7	GO:0016705
GeneOntologyMolecularFunction	androsterone dehydrogenase (B-specific) activity	AKR1C1 AKR1C2	2.20e-04	4	122	2	GO:0047042
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	2.20e-04	4	122	2	GO:0005219
GeneOntologyMolecularFunction	ketoreductase activity	AKR1C1 AKR1C2	2.20e-04	4	122	2	GO:0045703
GeneOntologyMolecularFunction	indanol dehydrogenase activity	AKR1C1 AKR1C2	2.20e-04	4	122	2	GO:0047718
GeneOntologyMolecularFunction	chlordecone reductase activity	AKR1C1 AKR1C2	2.20e-04	4	122	2	GO:0047743
GeneOntologyMolecularFunction	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0047115
GeneOntologyMolecularFunction	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0047020
GeneOntologyMolecularFunction	17-beta-ketosteroid reductase (NADPH) activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0072555
GeneOntologyMolecularFunction	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0047006
GeneOntologyMolecularFunction	lithocholic acid binding	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:1902121
GeneOntologyMolecularFunction	ketosteroid monooxygenase activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0047086
GeneOntologyMolecularFunction	Delta4-3-oxosteroid 5beta-reductase activity	AKR1C1 AKR1C2	3.66e-04	5	122	2	GO:0047787
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3A KDM3B	3.66e-04	5	122	2	GO:0140683
GeneOntologyMolecularFunction	NADPH binding	SRD5A1 AKR1C1 AKR1C2	5.22e-04	26	122	3	GO:0070402
GeneOntologyMolecularFunction	RNA polymerase III type 3 promoter sequence-specific DNA binding	MTOR SNAPC4	5.47e-04	6	122	2	GO:0001006
GeneOntologyMolecularFunction	geranylgeranyl reductase activity	AKR1C1 AKR1C2	5.47e-04	6	122	2	GO:0045550
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR2 RYR3	5.47e-04	6	122	2	GO:0048763
GeneOntologyMolecularFunction	monooxygenase activity	CYP1A1 CYP1A2 CYP27B1 AKR1C1 AKR1C2	7.04e-04	115	122	5	GO:0004497
GeneOntologyMolecularFunction	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	AKR1C1 AKR1C2	7.62e-04	7	122	2	GO:0072582
GeneOntologyMolecularFunction	hydroperoxy icosatetraenoate dehydratase activity	CYP1A1 CYP1A2	7.62e-04	7	122	2	GO:0106256
GeneOntologyMolecularFunction	RNA polymerase III cis-regulatory region sequence-specific DNA binding	MTOR SNAPC4	7.62e-04	7	122	2	GO:0000992
GeneOntologyMolecularFunction	RNA polymerase III transcription regulatory region sequence-specific DNA binding	MTOR SNAPC4	1.01e-03	8	122	2	GO:0001016
GeneOntologyMolecularFunction	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	AKR1C1 AKR1C2	1.01e-03	8	122	2	GO:0047024
GeneOntologyMolecularFunction	androsterone dehydrogenase activity	AKR1C1 AKR1C2	1.01e-03	8	122	2	GO:0047023
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP1A1 CYP1A2	1.01e-03	8	122	2	GO:0101021
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	SRD5A1 AKR1C1 AKR1C2	1.16e-03	34	122	3	GO:0016628
GeneOntologyMolecularFunction	androstan-3-alpha,17-beta-diol dehydrogenase activity	AKR1C1 AKR1C2	1.30e-03	9	122	2	GO:0047044
GeneOntologyMolecularFunction	NADP+ binding	AKR1C1 AKR1C2	1.30e-03	9	122	2	GO:0070401
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	CYP1A1 CYP1A2 POLG UROC1	1.61e-03	82	122	4	GO:0016835
GeneOntologyMolecularFunction	testosterone 17-beta-dehydrogenase (NADP+) activity	AKR1C1 AKR1C2	1.61e-03	10	122	2	GO:0047045
GeneOntologyMolecularFunction	bile acid binding	AKR1C1 AKR1C2	1.61e-03	10	122	2	GO:0032052
GeneOntologyMolecularFunction	steroid dehydrogenase activity	SRD5A1 AKR1C1 AKR1C2	1.73e-03	39	122	3	GO:0016229
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP1A1 CYP1A2	1.96e-03	11	122	2	GO:0101020
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1C1 AKR1C2	3.21e-03	14	122	2	GO:0004032
GeneOntologyMolecularFunction	retinal dehydrogenase activity	AKR1C1 AKR1C2	3.21e-03	14	122	2	GO:0001758
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM3A KDM3B	3.21e-03	14	122	2	GO:0032454
GeneOntologyMolecularFunction	ABC-type transporter activity	ATP13A1 ABCA7 ABCC10	3.34e-03	49	122	3	GO:0140359
GeneOntologyBiologicalProcess	steroid catabolic process	CYP1A2 CYP27B1 SRD5A1 AKR1C1 AKR1C2	1.49e-06	34	120	5	GO:0006706
GeneOntologyBiologicalProcess	negative regulation of vitamin metabolic process	CYP27B1 AKR1C1 AKR1C2	2.24e-05	10	120	3	GO:0046137
GeneOntologyBiologicalProcess	retinoic acid biosynthetic process	CYP1A1 AKR1C1 AKR1C2	6.67e-05	14	120	3	GO:0002138
GeneOntologyBiologicalProcess	diterpenoid biosynthetic process	CYP1A1 AKR1C1 AKR1C2	8.30e-05	15	120	3	GO:0016102
GeneOntologyBiologicalProcess	negative regulation of hormone metabolic process	CYP27B1 AKR1C1 AKR1C2	1.02e-04	16	120	3	GO:0032351
GeneOntologyBiologicalProcess	vitamin metabolic process	CYP1A1 ACP3 CYP27B1 AKR1C1 AKR1C2 SLC2A1	1.29e-04	133	120	6	GO:0006766
GeneOntologyBiologicalProcess	regulation of vitamin metabolic process	CYP27B1 AKR1C1 AKR1C2	1.47e-04	18	120	3	GO:0030656
GeneOntologyBiologicalProcess	condensed mesenchymal cell proliferation	DCHS2 FAT4	2.00e-04	4	120	2	GO:0072137
GeneOntologyBiologicalProcess	response to jasmonic acid	AKR1C1 AKR1C2	2.00e-04	4	120	2	GO:0009753
GeneOntologyBiologicalProcess	progesterone catabolic process	AKR1C1 AKR1C2	2.00e-04	4	120	2	GO:0006709
GeneOntologyBiologicalProcess	cellular response to jasmonic acid stimulus	AKR1C1 AKR1C2	2.00e-04	4	120	2	GO:0071395
GeneOntologyBiologicalProcess	C21-steroid hormone catabolic process	AKR1C1 AKR1C2	2.00e-04	4	120	2	GO:0008208
GeneOntologyBiologicalProcess	diterpenoid metabolic process	CYP1A1 CYP1A2 SRD5A1 AKR1C1 AKR1C2	2.23e-04	94	120	5	GO:0016101
GeneOntologyBiologicalProcess	hormone catabolic process	SRD5A1 AKR1C1 AKR1C2	2.37e-04	21	120	3	GO:0042447
GeneOntologyBiologicalProcess	terpenoid biosynthetic process	CYP1A1 AKR1C1 AKR1C2	2.37e-04	21	120	3	GO:0016114
GeneOntologyBiologicalProcess	parturition	CYP1A1 AKR1C1 AKR1C2	2.73e-04	22	120	3	GO:0007567
GeneOntologyBiologicalProcess	progesterone metabolic process	SRD5A1 AKR1C1 AKR1C2	2.73e-04	22	120	3	GO:0042448
GeneOntologyBiologicalProcess	carboxylic acid metabolic process	CYP1A1 CYP1A2 TTC36 SHMT2 UROC1 UST AKR1C1 AKR1C2 SLC2A1 PRKAG3 NCOR1 MTOR OGDHL PCCB ABCC10 ACSL5	3.30e-04	1035	120	16	GO:0019752
GeneOntologyBiologicalProcess	farnesol metabolic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:0016487
GeneOntologyBiologicalProcess	farnesol catabolic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:0016488
GeneOntologyBiologicalProcess	negative regulation of isoprenoid metabolic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:0045827
GeneOntologyBiologicalProcess	sesquiterpenoid catabolic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:0016107
GeneOntologyBiologicalProcess	olefinic compound catabolic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:0120256
GeneOntologyBiologicalProcess	dibenzo-p-dioxin metabolic process	CYP1A1 CYP1A2	3.32e-04	5	120	2	GO:0018894
GeneOntologyBiologicalProcess	negative regulation of retinoic acid biosynthetic process	AKR1C1 AKR1C2	3.32e-04	5	120	2	GO:1900053
GeneOntologyBiologicalProcess	terpenoid metabolic process	CYP1A1 CYP1A2 SRD5A1 AKR1C1 AKR1C2	3.72e-04	105	120	5	GO:0006721
GeneOntologyBiologicalProcess	primary alcohol metabolic process	CYP1A1 CYP1A2 ACP3 AKR1C1 AKR1C2	3.89e-04	106	120	5	GO:0034308
GeneOntologyBiologicalProcess	lipid catabolic process	CYP1A2 CYP27B1 SRD5A1 AKR1C1 AKR1C2 MTOR PLA2G6 PCCB ACSL5	4.00e-04	382	120	9	GO:0016042
GeneOntologyBiologicalProcess	oxoacid metabolic process	CYP1A1 CYP1A2 TTC36 SHMT2 UROC1 UST AKR1C1 AKR1C2 SLC2A1 PRKAG3 NCOR1 MTOR OGDHL PCCB ABCC10 ACSL5	4.20e-04	1058	120	16	GO:0043436
GeneOntologyBiologicalProcess	organic acid metabolic process	CYP1A1 CYP1A2 TTC36 SHMT2 UROC1 UST AKR1C1 AKR1C2 SLC2A1 PRKAG3 NCOR1 MTOR OGDHL PCCB ABCC10 ACSL5	4.47e-04	1064	120	16	GO:0006082
GeneOntologyBiologicalProcess	sesquiterpenoid metabolic process	AKR1C1 AKR1C2	4.96e-04	6	120	2	GO:0006714
GeneOntologyBiologicalProcess	polyprenol catabolic process	AKR1C1 AKR1C2	4.96e-04	6	120	2	GO:0016095
GeneOntologyBiologicalProcess	response to Thyroglobulin triiodothyronine	SLC2A1 NCOR1	4.96e-04	6	120	2	GO:1904016
Domain	Cyt_P450_E_grp-I_CYP1	CYP1A1 CYP1A2	4.16e-05	2	121	2	IPR008066
Domain	Ryanodine_rcpt	RYR2 RYR3	1.24e-04	3	121	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR2 RYR3	1.24e-04	3	121	2	IPR009460
Domain	RyR	RYR2 RYR3	1.24e-04	3	121	2	PF02026
Domain	RR_TM4-6	RYR2 RYR3	1.24e-04	3	121	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	1.24e-04	3	121	2	IPR013333
Domain	Coact_PPARg	FAM120B FAM120C	2.48e-04	4	121	2	IPR026784
Domain	ADAM_spacer1	ADAMTS10 ADAMTSL5 ADAMTSL4	4.27e-04	23	121	3	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTSL5 ADAMTSL4	4.27e-04	23	121	3	PF05986
Domain	RIH_assoc-dom	RYR2 RYR3	6.14e-04	6	121	2	IPR013662
Domain	Ins145_P3_rec	RYR2 RYR3	6.14e-04	6	121	2	PF08709
Domain	RIH_assoc	RYR2 RYR3	6.14e-04	6	121	2	PF08454
Domain	RIH_dom	RYR2 RYR3	6.14e-04	6	121	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	6.14e-04	6	121	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	6.14e-04	6	121	2	IPR015925
Domain	-	RYR2 RYR3	6.14e-04	6	121	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 RYR3	6.14e-04	6	121	2	PF01365
Pathway	WP_BENZOAPYRENE_METABOLISM	CYP1A1 AKR1C1 AKR1C2	1.61e-05	9	83	3	M39344
Pathway	KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM	CYP1A1 AKR1C1 AKR1C2	3.14e-05	11	83	3	M47812
Pathway	WP_GLUCOCORTICOID_BIOSYNTHESIS	SRD5A1 AKR1C1 AKR1C2	6.84e-05	14	83	3	M46449
Pathway	WP_MINERALOCORTICOID_BIOSYNTHESIS	SRD5A1 AKR1C1 AKR1C2	6.84e-05	14	83	3	M46453
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTSL5 POFUT2 ADAMTSL4	7.85e-05	39	83	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTSL5 POFUT2 ADAMTSL4	7.85e-05	39	83	4	MM15165
Pathway	WP_15Q25_COPY_NUMBER_VARIATION	SHANK1 SLC2A1 RYR2 AP3D1	1.51e-04	46	83	4	M48105
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	CYP1A1 SRD5A1 AKR1C1 AKR1C2	3.03e-04	55	83	4	M14933
Pathway	WP_THERMOGENESIS	KDM3A KDM3B PRKAG3 MTOR ACSL5	4.34e-04	108	83	5	M39746
Pathway	REACTOME_ARACHIDONIC_ACID_METABOLISM	CYP1A1 CYP1A2 AKR1C1 AKR1C2	4.52e-04	61	83	4	MM14861
Pathway	REACTOME_FATTY_ACID_METABOLISM	CYP1A1 CYP1A2 AKR1C1 AKR1C2 PCCB ACSL5	4.93e-04	170	83	6	MM15573
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 ATP13A1 POLG PIEZO1 KDM3B GRB10 CARD10 INO80 GTF2IRD1 ABCA7 SLC2A1 NCOR1 KMT2C NADSYN1 RPAP1 ADAMTSL5 MTOR XPO6 OGDHL PLA2G6 SNAPC4 AP3D1 ABCC10 EVI5L	1.59e-12	1105	126	24	35748872
Pubmed	Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.	SRD5A1 AKR1C1 AKR1C2	4.62e-07	5	126	3	15212687
Pubmed	Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.	SRD5A1 AKR1C1 AKR1C2	4.62e-07	5	126	3	16984997
Pubmed	Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.	SRD5A1 AKR1C1 AKR1C2	4.62e-07	5	126	3	17064890
Pubmed	Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.	SRD5A1 AKR1C1 AKR1C2	4.62e-07	5	126	3	18003893
Pubmed	Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.	SRD5A1 AKR1C1 AKR1C2	1.61e-06	7	126	3	19846565
Pubmed	The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.	GRB10 MTOR	1.30e-05	2	126	2	21659604
Pubmed	Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.	CYP1A1 CYP1A2	1.30e-05	2	126	2	2425809
Pubmed	Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.	AKR1C1 AKR1C2	1.30e-05	2	126	2	8573067
Pubmed	Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.	CYP1A1 CYP1A2	1.30e-05	2	126	2	3000715
Pubmed	Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.	AKR1C1 AKR1C2	1.30e-05	2	126	2	15492289
Pubmed	Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.	CYP1A1 CYP1A2	1.30e-05	2	126	2	12147246
Pubmed	Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.	CYP1A1 CYP1A2	1.30e-05	2	126	2	17852022
Pubmed	Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.	CYP1A1 CYP1A2	1.30e-05	2	126	2	14980704
Pubmed	Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation.	SLC2A1 MTOR	1.30e-05	2	126	2	25385184
Pubmed	Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues.	CYP1A1 CYP1A2	1.30e-05	2	126	2	7781742
Pubmed	Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.	CYP1A1 CYP1A2	1.30e-05	2	126	2	11207026
Pubmed	Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.	CYP1A1 CYP1A2	1.30e-05	2	126	2	3785172
Pubmed	Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.	CYP1A1 CYP1A2	1.30e-05	2	126	2	3860967
Pubmed	Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.	CYP1A1 CYP1A2	1.30e-05	2	126	2	16609368
Pubmed	Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.	CYP1A1 CYP1A2	1.30e-05	2	126	2	15094312
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	1.30e-05	2	126	2	8898078
Pubmed	CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.	CYP1A1 CYP1A2	1.30e-05	2	126	2	19285097
Pubmed	GLUT1 enhances mTOR activity independently of TSC2 and AMPK.	SLC2A1 MTOR	1.30e-05	2	126	2	21613414
Pubmed	[Association of polymorph variants of CYP1A2 and CYP1A1 genes with reproductive and thyroid diseases in female workers of petrochemical industry].	CYP1A1 CYP1A2	1.30e-05	2	126	2	22855999
Pubmed	Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.	CYP1A1 CYP1A2	1.30e-05	2	126	2	12438513
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	1.30e-05	2	126	2	14550562
Pubmed	Formation of AP-3 transport intermediates requires Vps41 function.	VPS41 AP3D1	1.30e-05	2	126	2	10559961
Pubmed	Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.	AKR1C1 AKR1C2	1.30e-05	2	126	2	21217827
Pubmed	Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.	CYP1A1 CYP1A2	1.30e-05	2	126	2	21262253
Pubmed	Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.	CYP1A1 CYP1A2	1.30e-05	2	126	2	26953171
Pubmed	Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.	CYP1A1 CYP1A2	1.30e-05	2	126	2	18493746
Pubmed	Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.	CYP1A1 CYP1A2	1.30e-05	2	126	2	32726451
Pubmed	A shuffled CYP1A library shows both structural integrity and functional diversity.	CYP1A1 CYP1A2	1.30e-05	2	126	2	17823232
Pubmed	Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.	CYP1A1 CYP1A2	1.30e-05	2	126	2	3988744
Pubmed	cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.	AKR1C1 AKR1C2	1.30e-05	2	126	2	8486699
Pubmed	CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.	CYP1A1 CYP1A2	1.30e-05	2	126	2	26643992
Pubmed	Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.	CYP1A1 CYP1A2	1.30e-05	2	126	2	22949628
Pubmed	Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways.	SLC2A1 MTOR	1.30e-05	2	126	2	28053105
Pubmed	Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.	CYP1A1 CYP1A2	1.30e-05	2	126	2	9295056
Pubmed	Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.	CYP1A1 CYP1A2	1.30e-05	2	126	2	25680282
Pubmed	Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene.	ABCA7 ARHGAP45	1.30e-05	2	126	2	11095984
Pubmed	Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.	AKR1C1 AKR1C2	1.30e-05	2	126	2	11514561
Pubmed	Important roles of the AKR1C2 and SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines.	SRD5A1 AKR1C2	1.30e-05	2	126	2	25463305
Pubmed	Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.	CYP1A1 CYP1A2	1.30e-05	2	126	2	25703676
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	1.30e-05	2	126	2	21531043
Pubmed	Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.	CYP1A1 CYP1A2	1.30e-05	2	126	2	4054433
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	1.30e-05	2	126	2	16678258
Pubmed	Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.	CYP1A1 CYP1A2	1.30e-05	2	126	2	31147315
Pubmed	Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.	CYP1A1 CYP1A2	1.30e-05	2	126	2	8001243
Pubmed	Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco.	CYP1A1 CYP1A2	1.30e-05	2	126	2	16402549
Pubmed	The effect of CYP1A1 and CYP1A2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.	CYP1A1 CYP1A2	1.30e-05	2	126	2	24443269
Pubmed	Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.	CYP1A1 CYP1A2	1.30e-05	2	126	2	16426572
Pubmed	The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population.	CYP1A1 CYP1A2	1.30e-05	2	126	2	33046100
Pubmed	CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.	CYP1A1 CYP1A2	1.30e-05	2	126	2	19276377
Pubmed	Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.	DCHS2 FAT4	1.30e-05	2	126	2	15003449
Pubmed	Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).	CYP1A1 CYP1A2	1.30e-05	2	126	2	17052995
Pubmed	Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture.	CYP1A1 CYP1A2	1.30e-05	2	126	2	1335375
Pubmed	Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.	CYP1A1 CYP1A2	1.30e-05	2	126	2	8095225
Pubmed	cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase.	AKR1C1 AKR1C2	1.30e-05	2	126	2	8011662
Pubmed	A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.	CYP1A1 CYP1A2	1.30e-05	2	126	2	16505155
Pubmed	Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.	AKR1C1 AKR1C2	1.30e-05	2	126	2	18654764
Pubmed	Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.	CYP1A1 CYP1A2	1.30e-05	2	126	2	8274012
Pubmed	Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.	CYP1A1 CYP1A2	1.30e-05	2	126	2	1452456
Pubmed	Amino-terminal sequence and structure of monoclonal antibody immunopurified cytochromes P-450.	CYP1A1 CYP1A2	1.30e-05	2	126	2	3718958
Pubmed	Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.	CYP1A1 CYP1A2	1.30e-05	2	126	2	14637164
Pubmed	Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population.	CYP1A1 CYP27B1	1.30e-05	2	126	2	12746631
Pubmed	Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.	CYP1A1 CYP1A2	1.30e-05	2	126	2	16516144
Pubmed	Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.	CYP1A1 CYP1A2	1.30e-05	2	126	2	28698457
Pubmed	[Association of cytochrome P450 genes polymorphisms (CYP1A1 and CYP1A2) with the development of chronic obstructive pulmonary disease in Bashkortostan].	CYP1A1 CYP1A2	1.30e-05	2	126	2	18389617
Pubmed	The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death.	AKR1C1 AKR1C2	1.30e-05	2	126	2	26934124
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	1.30e-05	2	126	2	14985349
Pubmed	Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450.	CYP1A1 CYP1A2	1.30e-05	2	126	2	6548461
Pubmed	Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.	CYP1A1 CYP1A2	1.30e-05	2	126	2	34242741
Pubmed	Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.	CYP1A1 CYP1A2	1.30e-05	2	126	2	10623596
Pubmed	Homozygosity for the 168His variant of the minor histocompatibility antigen HA-1 is associated with reduced risk of primary Sjögren's syndrome.	ABCA7 ARHGAP45	1.30e-05	2	126	2	15593299
Pubmed	Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.	CYP1A1 CYP1A2	1.30e-05	2	126	2	21081470
Pubmed	Early life environment, neurodevelopment and the interrelation with atopy.	CYP1A1 CYP1A2 CYP27B1	2.51e-05	16	126	3	20701904
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM3A ARHGAP32 AKAP9 SACS SEL1L3	3.46e-05	101	126	5	9872452
Pubmed	Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.	AKR1C1 AKR1C2	3.90e-05	3	126	2	19320734
Pubmed	Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.	SLC2A1 MTOR	3.90e-05	3	126	2	26023239
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	3.90e-05	3	126	2	18403125
Pubmed	Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.	AKR1C1 AKR1C2	3.90e-05	3	126	2	31780644
Pubmed	Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.	CYP1A1 CYP1A2	3.90e-05	3	126	2	17997381
Pubmed	CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD.	CYP1A1 CYP1A2	3.90e-05	3	126	2	20080081
Pubmed	Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss.	CYP1A1 CYP1A2	3.90e-05	3	126	2	15299091
Pubmed	Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer.	CYP1A1 CYP1A2	3.90e-05	3	126	2	15734958
Pubmed	Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.	RYR2 RYR3	3.90e-05	3	126	2	29730765
Pubmed	Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.	AKR1C1 AKR1C2	3.90e-05	3	126	2	13678667
Pubmed	Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.	CYP1A1 CYP1A2	3.90e-05	3	126	2	24668907
Pubmed	Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan.	CYP1A1 CYP1A2	3.90e-05	3	126	2	19452301
Pubmed	Interleukin 1β regulates progesterone metabolism in human cervical fibroblasts.	AKR1C1 AKR1C2	3.90e-05	3	126	2	22064385
Pubmed	Meat intake, metabolic genes and colorectal cancer.	CYP1A1 CYP1A2	3.90e-05	3	126	2	12484238
Pubmed	Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1.	CYP1A1 CYP1A2	3.90e-05	3	126	2	38081439
Pubmed	Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.	CYP1A1 CYP1A2	3.90e-05	3	126	2	24497629
Pubmed	CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.	CYP1A1 CYP1A2	3.90e-05	3	126	2	19666078
Pubmed	Progestin effects on expression of AKR1C1-AKR1C3, SRD5A1 and PGR in the Z-12 endometriotic epithelial cell line.	SRD5A1 AKR1C1	3.90e-05	3	126	2	23183084
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR2 RYR3	3.90e-05	3	126	2	7876312
Pubmed	Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.	CYP1A1 CYP1A2	3.90e-05	3	126	2	18814841
Pubmed	Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways.	CYP1A1 CYP1A2	3.90e-05	3	126	2	23956430
Interaction	TOP3B interactions	VWA5B2 ATP13A1 POLG PIEZO1 KDM3B GRB10 CARD10 INO80 GTF2IRD1 ABCA7 SLC2A1 NCOR1 KMT2C NADSYN1 RPAP1 ADAMTSL5 FAM120C MTOR XPO6 OGDHL PLA2G6 SNAPC4 ADAMTSL4 AP3D1 ABCC10 EVI5L	4.93e-07	1470	121	26	int:TOP3B
Cytoband	4q31.3	DCHS2 GLRB FHIP1A	8.58e-05	31	126	3	4q31.3
Cytoband	10p15-p14	AKR1C1 AKR1C2	1.11e-04	6	126	2	10p15-p14
GeneFamily	Cadherin related	DCHS2 FAT4 CDHR2	4.84e-05	17	77	3	24
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	5.36e-05	3	77	2	287
GeneFamily	Cytochrome P450 family 1	CYP1A1 CYP1A2	1.07e-04	4	77	2	1000
GeneFamily	ADAMTS like	ADAMTSL5 ADAMTSL4	3.71e-04	7	77	2	947
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP32 FAM13B ARHGAP45	1.26e-03	50	77	3	721
GeneFamily	INO80 complex \|SRCAP complex	ACTR8 INO80	1.81e-03	15	77	2	595
GeneFamily	Aldo-keto reductases	AKR1C1 AKR1C2	1.81e-03	15	77	2	399
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM3A KDM3B	4.65e-03	24	77	2	485
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	KDM3A POLG GTF2IRD1 NCOR1 PLA2G6 SNAPC4 AP3D1 SON	1.29e-06	166	124	8	M6826
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	DDR1 ATP13A1 POLG COLGALT1 ABCA7 SLC2A1 RPAP1 POFUT2 ADAMTSL4 ABCC10 SON	1.16e-05	457	124	11	M1613
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	DDR1 ATP13A1 POLG COLGALT1 ABCA7 SLC2A1 RPAP1 POFUT2 ADAMTSL4 ABCC10 SON	1.50e-05	470	124	11	MM1053
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 UST RYR3 CDH24 VWA5A FHIP1A	7.78e-06	167	125	6	a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 UST RYR3 CDH24 VWA5A FHIP1A	8.33e-06	169	125	6	0c341f91dc21aaf92bead18d59684d11510502ce
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 FAT4 UST CDH24 VWA5A FHIP1A	8.62e-06	170	125	6	84d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 FAT4 UST CDH24 VWA5A FHIP1A	9.21e-06	172	125	6	cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 RYR3 CDH24 VWA5A SEL1L3 FHIP1A	9.84e-06	174	125	6	e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	REC8 MYH7B PIEZO1 SHMT2 SLX9 UNC80	1.53e-05	188	125	6	34873972dff9284dfcd26bb698c9d1df007f1cbb
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 NCOR1 KMT2C AKAP9 UNC80 SON	1.88e-05	195	125	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 NCOR1 KMT2C AKAP9 UNC80 SON	1.88e-05	195	125	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 UST RYR3 CDH24 VWA5A FHIP1A	2.16e-05	200	125	6	501cd2b4e55444fc5fdd93ebbcfc0616442b110b
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 FAT4 UST RYR3 CDH24 FHIP1A	2.16e-05	200	125	6	d31e26387d879ee30731c497cea6aaf4746e40d9
Drug	7-hydroxyflavone	CYP1A1 CYP1A2 AKR1C1 SLC2A1	9.06e-08	9	120	4	CID005281894
Drug	7-hydroxyflavone	CYP1A1 CYP1A2 AKR1C1 SLC2A1	2.35e-07	11	120	4	ctd:C429845
Drug	15,16-dihydrotanshinone I	CYP1A1 CYP1A2 SLC2A1 MTOR	7.05e-07	14	120	4	ctd:C401932
Drug	5,12-naphthacenequinone	CYP1A1 CYP1A2 AKR1C1	1.42e-06	5	120	3	ctd:C468646
Drug	AC1L8ZBW	CYP1A1 AKR1C1 AKR1C2 PARVA	2.68e-06	19	120	4	CID000435356
Drug	metamitron	CYP1A1 CYP1A2 PARVA	2.82e-06	6	120	3	CID000038854
Drug	benzotriphenylene	CYP1A1 CYP1A2 AKR1C1	4.92e-06	7	120	3	ctd:C006710
Drug	1,7-phenanthroline	CYP1A1 CYP1A2 AKR1C1	7.84e-06	8	120	3	ctd:C053486
Drug	Estrone [53-16-7]; Down 200; 14.8uM; PC3; HT_HG-U133A	FAT4 OGFR CYP27B1 RTL10 FAM120C GLRB PARVA PLA2G6	8.95e-06	194	120	8	6647_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	CYP1A1 OGFR RTL10 ABCA7 MFNG FAM120C PLA2G6 SNAPC4	9.29e-06	195	120	8	5573_DN
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A	ACTR8 OGFR POLG CYP27B1 RPAP1 PLEKHG6 MTOR XPO6	9.29e-06	195	120	8	1652_DN
Drug	Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	CYP1A2 OGFR PTPN18 RYR2 TENM3 VWA5A PLA2G6 SNAPC4	1.08e-05	199	120	8	4294_DN
Drug	almotriptan	CYP1A1 CYP1A2 HTR1D	1.67e-05	10	120	3	ctd:C409045
Drug	PCB 95	CYP1A1 RYR2 RYR3	1.67e-05	10	120	3	CID000038012
Drug	M3/M4	CYP1A2 RYR2 RYR3 MTOR	2.35e-05	32	120	4	CID000486507
Drug	2-methoxy-4-aminoazobenzene	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C053767
Drug	3,4,3',4'-tetrachloroazoxybenzene	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C013280
Drug	cloflucarban	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C005055
Drug	musk xylene	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C031447
Drug	sesamex	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C100180
Drug	Canthaxanthin	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:D016644
Drug	Pigment Yellow 74	CYP1A1 CYP1A2	2.75e-05	2	120	2	CID000022829
Drug	pyridoxal isonicotinoyl hydrazone	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C021079
Drug	(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE	AKR1C1 AKR1C2	2.75e-05	2	120	2	DB07768
Drug	nitroaniline	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C008625
Drug	7H-dibenzo(c,g)carbazole	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C013478
Drug	2,7-dinitrofluorene	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C085049
Drug	beta-apo-8'-carotenal	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C110652
Drug	propachlor	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C011088
Drug	allocryptopine	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C109505
Drug	2,7-FAA	CYP1A1 CYP1A2	2.75e-05	2	120	2	CID000009352
Drug	protopine	CYP1A1 CYP1A2	2.75e-05	2	120	2	ctd:C009093
Drug	methylparaoxon	CYP1A1 AKR1C1 AKR1C2	3.03e-05	12	120	3	ctd:C008480
Drug	clozapine N-oxide	CYP1A1 CYP1A2 SLC2A1	3.93e-05	13	120	3	CID000036727
Drug	4-chloro-m-cresol	CYP1A2 AKR1C2 RYR2 RYR3	4.24e-05	37	120	4	CID000001732
Drug	Dydrogesterone	SRD5A1 AKR1C1 AKR1C2	4.98e-05	14	120	3	ctd:D004394
Drug	5-alpha-Dihydroprogesterone	SRD5A1 AKR1C1 AKR1C2	4.98e-05	14	120	3	ctd:D043582
Drug	6-.beta.-Naltrexol	OGFR AKR1C1 AKR1C2	4.98e-05	14	120	3	CID000631219
Drug	Mefenamic Acid	CYP1A1 CYP1A2 AKR1C1 AKR1C2	5.23e-05	39	120	4	ctd:D008528
Drug	Dantrolene	CYP1A1 CYP1A2 RYR2 RYR3	6.39e-05	41	120	4	ctd:D003620
Drug	Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A	CYP1A1 OGFR ABCA7 FAM120C MTOR VWA5A PARVA	7.73e-05	194	120	7	2284_DN
Drug	wortmannin from Penicillium funiculosum; Down 200; 0.01uM; PC3; HT_HG-U133A	CYP1A2 ARHGAP32 DNAH3 ACTR8 CYP27B1 ZNF318 XPO6	7.98e-05	195	120	7	1243_DN
Drug	benzo(a)fluorene	CYP1A1 AKR1C1	8.24e-05	3	120	2	ctd:C041511
Drug	2,3-diaminotoluene	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C100420
Drug	zolmitriptan	CYP1A2 HTR1D	8.24e-05	3	120	2	ctd:C089750
Drug	2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C522525
Drug	2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C519626
Drug	scutellarein	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C458179
Drug	genkwanin	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C014568
Drug	cis-diammineplatinum(II	RYR2 RYR3	8.24e-05	3	120	2	CID000159790
Drug	1-methoxyrutaecarpine	CYP1A1 CYP1A2	8.24e-05	3	120	2	CID005319487
Drug	2-hydroxyheptanoic acid	RYR2 RYR3	8.24e-05	3	120	2	CID002750949
Drug	Suppressor Factors, Immunologic	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:D013491
Drug	8N3-cADPR	RYR2 RYR3	8.24e-05	3	120	2	CID000127713
Drug	alyssin	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C524316
Drug	2-oxohexyl isothiocyanate	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C524315
Drug	aminodantrolene	RYR2 RYR3	8.24e-05	3	120	2	CID009570289
Drug	Trichloroepoxypropane	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:D014239
Drug	cyclopentanol	AKR1C1 AKR1C2	8.24e-05	3	120	2	ctd:C016327
Drug	3-aminofluorene	CYP1A1 CYP1A2	8.24e-05	3	120	2	CID000022818
Drug	1-aminofluorene	CYP1A1 CYP1A2	8.24e-05	3	120	2	CID000022817
Drug	2,2',4,6'-tetramethoxystilbene	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C541980
Drug	6-nitrobenzo(a)pyrene	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C034699
Drug	chlortoluron	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C007033
Drug	cyclopentanone	AKR1C1 AKR1C2	8.24e-05	3	120	2	ctd:C007201
Drug	Aminoquinolines	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:D000634
Drug	2-hydroxycarbazole	RYR2 RYR3	8.24e-05	3	120	2	CID000093551
Drug	7-(deoxyadenosin-N(6)--yl)aristolactam II	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C405699
Drug	5-dihydrodeoxycorticosterone	AKR1C1 AKR1C2	8.24e-05	3	120	2	ctd:C454687
Drug	1,2,3,7,8-pentachlorodibenzofuran	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C057584
Drug	4-benzoylbenzoic acid	AKR1C1 AKR1C2	8.24e-05	3	120	2	ctd:C058818
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR2 RYR3	8.24e-05	3	120	2	CID005748312
Drug	7-nitrobenzanthracene	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C038954
Drug	1,2-dichloroethylene	CYP1A1 CYP1A2	8.24e-05	3	120	2	ctd:C035384
Drug	dichloro(4-cymene)ruthenium(II)	AKR1C1 AKR1C2	8.24e-05	3	120	2	ctd:C530610
Drug	Mimosine [500-44-7]; Down 200; 20.2uM; PC3; HT_HG-U133A	CYP1A2 PTPN18 ABCA7 PLEKHG6 TENM3 PARVA SNAPC4	8.24e-05	196	120	7	6703_DN
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; HL60; HG-U133A	CYP1A2 HECTD3 RPAP3 OGFR GRB10 PCYOX1L ACSL5	8.24e-05	196	120	7	1964_DN
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A	MTG1 ACTR8 OGFR GRB10 MFNG FAM120C PLA2G6	8.51e-05	197	120	7	6010_DN
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; HL60; HG-U133A	CYP1A2 OGFR KDM3B PTPN18 PLA2G6 SNAPC4 POFUT2	8.51e-05	197	120	7	1394_DN
Drug	Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CYP1A1 CDHR2 ACP3 ABCA7 FAM120C GLRB CCDC87	8.51e-05	197	120	7	6043_UP
Drug	Napelline [5008-52-6]; Down 200; 11.2uM; PC3; HT_HG-U133A	CDHR2 OGFR UPF3A PTPN18 TENM3 MTOR VPS41	8.78e-05	198	120	7	4486_DN
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CYP1A1 POLG ZNF318 RYR2 FAM120C PARVA ACSL5	8.78e-05	198	120	7	3433_UP
Drug	Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; PC3; HT_HG-U133A	CYP1A1 DNAH3 OGFR UPF3A MFNG FAM120C OGDHL	8.78e-05	198	120	7	3711_DN
Drug	Avermectin B1 [71751-41-2]; Down 200; 4.8uM; PC3; HT_HG-U133A	CYP27B1 SRD5A1 PTPN18 GLRB PARVA SNAPC4 POFUT2	8.78e-05	198	120	7	5864_DN
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; HL60; HT_HG-U133A	ARHGAP32 SUPT3H ACP3 GTF2IRD1 NCOR1 RPAP1 VWA5A	8.78e-05	198	120	7	2411_DN
Drug	naphthalene-1,2-dihydrodiol	CYP1A1 CYP1A2 AKR1C1 AKR1C2	9.25e-05	45	120	4	CID000000362
Drug	androstane-3,17-dione	SRD5A1 AKR1C1 AKR1C2 AP3D1	1.51e-04	51	120	4	CID000000443
Drug	benzo(a)pyrene-7,8-dione	CYP1A1 AKR1C1 AKR1C2	1.52e-04	20	120	3	ctd:C076588
Drug	1-chloropyrene	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C040345
Drug	purpurin	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C511975
Drug	2-nitrofluoranthene	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C049030
Drug	7-methoxyresorufin	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C076580
Drug	2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C520611
Drug	PCB74	RYR2 RYR3	1.64e-04	4	120	2	CID000036218
Drug	musk ketone	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C031448
Drug	3,6-dinitrobenzopyrene	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C068923
Drug	PY74	CYP1A1 CYP1A2	1.64e-04	4	120	2	CID000017893
Drug	cloxazolam	AKR1C1 AKR1C2	1.64e-04	4	120	2	ctd:C005522
Drug	N-methyl-7H-dibenzo(c,g)carbazole	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C041150
Drug	terbutryne	CYP1A1 CYP1A2	1.64e-04	4	120	2	ctd:C010347
Disease	5-hydroxy-2-methylpyridine sulfate measurement	CYP1A1 CYP1A2	1.67e-05	2	121	2	EFO_0801051
Disease	serum clozapine measurement	CYP1A1 CYP1A2	1.67e-05	2	121	2	EFO_0600041
Disease	response to methotrexate	UST AKR1C1 AKR1C2	3.62e-05	16	121	3	GO_0031427
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	4.99e-05	3	121	2	DOID:3529 (implicated_via_orthology)
Disease	stomatocytic anemia	PIEZO1 SLC2A1	4.99e-05	3	121	2	C0272048
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	4.99e-05	3	121	2	DOID:8545 (implicated_via_orthology)
Disease	Neoplasms, Hormone-Dependent	AKR1C1 AKR1C2	4.99e-05	3	121	2	C0027661
Disease	Stomatocytosis Result	PIEZO1 SLC2A1	4.99e-05	3	121	2	C0677598
Disease	X-21286 measurement	CYP1A1 CYP1A2	9.95e-05	4	121	2	EFO_0800804
Disease	Hermaphroditism	AKR1C1 AKR1C2	1.65e-04	5	121	2	C0019269
Disease	Ambiguous Genitalia	AKR1C1 AKR1C2	1.65e-04	5	121	2	C0266362
Disease	Pseudohermaphroditism	AKR1C1 AKR1C2	1.65e-04	5	121	2	C0033804
Disease	Intersex Conditions	AKR1C1 AKR1C2	1.65e-04	5	121	2	C2930618
Disease	Sex Differentiation Disorders	AKR1C1 AKR1C2	1.65e-04	5	121	2	C2930619
Disease	creatinine measurement	CYP1A1 CYP1A2 MYH7B OGFR GRB10 CARD10 GATA5 INO80 AKR1C1 USP32 PLA2G6 UNC80 ABCC10	2.30e-04	995	121	13	EFO_0004518
Disease	porphyria cutanea tarda (is_implicated_in)	CYP1A1 CYP1A2	2.47e-04	6	121	2	DOID:3132 (is_implicated_in)
Disease	Liver carcinoma	CYP1A1 CYP1A2 CPEB3 TTC36 UROC1 AKR1C2 SLC2A1 KMT2C MTOR	2.51e-04	507	121	9	C2239176
Disease	Epileptic encephalopathy	SLC2A1 RYR3 MTOR	2.52e-04	30	121	3	C0543888
Disease	Disorders of Sex Development	AKR1C1 AKR1C2	3.46e-04	7	121	2	C0036875
Disease	plasma clozapine measurement	CYP1A1 CYP1A2	4.59e-04	8	121	2	EFO_0600038
Disease	memory impairment	FAT4 LRRC37B	4.59e-04	8	121	2	EFO_0001072
Disease	Endometrioma	SRD5A1 UST AKR1C1 AKR1C2 NCOR1	5.43e-04	161	121	5	C0269102
Disease	Endometriosis	SRD5A1 UST AKR1C1 AKR1C2 NCOR1	5.43e-04	161	121	5	C0014175
Disease	advanced glycation end-product measurement	CYP1A1 CYP1A2	5.89e-04	9	121	2	EFO_0007819
Disease	cardiovascular disease	CYP1A2 PRSS8 CYP27B1 ZNF318 UPF3A PRKAG3 PCCB ABCC10	6.10e-04	457	121	8	EFO_0000319
Disease	Colorectal Carcinoma	SHANK1 CYP1A2 DNAH3 GATA5 KMT2C AKAP9 RPAP1 CFAP77 SACS ACSL5	6.45e-04	702	121	10	C0009402
Disease	theophylline measurement	CYP1A1 CYP1A2	7.35e-04	10	121	2	EFO_0021180
Disease	sweet beverage consumption measurement	CYP1A1 CYP1A2	7.35e-04	10	121	2	EFO_0010090
Disease	1,7-dimethylurate measurement	CYP1A1 CYP1A2	7.35e-04	10	121	2	EFO_0021512
Disease	nasopharynx carcinoma (is_marker_for)	KDM3A KMT2C SNRPD1	7.36e-04	43	121	3	DOID:9261 (is_marker_for)
Disease	1-methylxanthine measurement	CYP1A1 CYP1A2	8.95e-04	11	121	2	EFO_0021174
Disease	plasma N-desmethylclozapine measurement	CYP1A1 CYP1A2	8.95e-04	11	121	2	EFO_0600039
Disease	5-acetylamino-6-amino-3-methyluracil measurement	CYP1A1 CYP1A2	8.95e-04	11	121	2	EFO_0800951
Disease	Long QT Syndrome	CYP1A1 RYR2	8.95e-04	11	121	2	C0023976
Disease	free androgen index	DDR1 ZNF318 GTF2IRD1 AKR1C2 PRKAG3 PCCB ABCC10	9.11e-04	374	121	7	EFO_0007005
Disease	paraxanthine measurement	CYP1A1 CYP1A2	1.07e-03	12	121	2	EFO_0021178
Disease	alcohol use disorder (implicated_via_orthology)	KDM3A KDM3B SHMT2 RYR2 RYR3	1.28e-03	195	121	5	DOID:1574 (implicated_via_orthology)
Disease	Carcinoma, Granular Cell	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0205644
Disease	Adenocarcinoma, Tubular	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0205642
Disease	Carcinoma, Cribriform	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0205643
Disease	Adenocarcinoma, Basal Cell	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0205641
Disease	Adenocarcinoma	DDR1 FAT4 KMT2C MTOR	1.35e-03	116	121	4	C0001418
Disease	prostate cancer (is_implicated_in)	CYP1A1 ACP3 SRD5A1 MTOR	1.40e-03	117	121	4	DOID:10283 (is_implicated_in)
Disease	gamma-glutamylglutamate measurement	ZNF318 ABCC10	1.47e-03	14	121	2	EFO_0021137
Disease	1,3,7-trimethylurate measurement	CYP1A1 CYP1A2	1.69e-03	15	121	2	EFO_0021172
Disease	Tremor, Rubral	UROC1 SLC2A1	1.93e-03	16	121	2	C0750940
Disease	Ataxia, Appendicular	UROC1 SLC2A1	1.93e-03	16	121	2	C0750937
Disease	Ataxia, Motor	UROC1 SLC2A1	1.93e-03	16	121	2	C0278161
Disease	Ataxia, Sensory	UROC1 SLC2A1	1.93e-03	16	121	2	C0240991
Disease	coffee consumption, cups of coffee per day measurement	CYP1A1 CYP1A2	1.93e-03	16	121	2	EFO_0004330, EFO_0006782
Disease	Abnormal coordination	UROC1 SLC2A1	1.93e-03	16	121	2	C0520966
Disease	Ataxia, Truncal	UROC1 SLC2A1	1.93e-03	16	121	2	C0427190
Disease	hearing loss	CYP1A1 GRB10 ZNF318	2.66e-03	67	121	3	EFO_0004238
Disease	caffeine metabolite measurement	CYP1A1 CYP1A2	2.72e-03	19	121	2	EFO_0007872
Disease	neurodegenerative disease (implicated_via_orthology)	FAT4 PRKAG3 OGDHL PLA2G6	3.05e-03	145	121	4	DOID:1289 (implicated_via_orthology)
Disease	Lung Injury	CYP1A1 CYP1A2	3.33e-03	21	121	2	C0273115
Disease	Chronic Lung Injury	CYP1A1 CYP1A2	3.33e-03	21	121	2	C2350344
Disease	anxiety disorder (implicated_via_orthology)	KDM3B NCOR1	3.65e-03	22	121	2	DOID:2030 (implicated_via_orthology)
Disease	Parkinson's disease (is_implicated_in)	CYP1A1 POLG PLA2G6	3.80e-03	76	121	3	DOID:14330 (is_implicated_in)
Disease	prostate cancer (is_marker_for)	KDM3A ACP3 SRD5A1 KMT2C	3.96e-03	156	121	4	DOID:10283 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
APLYDDALFLRTPQA	PTPN18	311	Q99952
AALQDALYPLSPRDA	EVI5L	746	Q96CN4
DLDYIRSPLPFQNRY	AKAP9	3836	Q99996
PFYIRANLTLPERAD	CARD10	706	Q9BWT7
FSPVPNLRYLDLSSN	AMIGO1	106	Q86WK6
RPSTPFFDLLQHRYL	CFAP77	211	Q6ZQR2
AQLRPSSNYLALRGP	ADAMTSL4	516	Q6UY14
SLLPRPSFLYRTIQD	PRKAG3	336	Q9UGI9
QIRHPDSPALLYQFR	ACTR8	366	Q9H981
LPEAAFLARTYLPSQ	COPB2	751	P35606
SRERPLPNIFNLYTI	ATP13A1	1041	Q9HD20
FRDQGRQVYLSRPPA	DDR1	861	Q08345
TFYRNSPARELHLPI	FAT4	4711	Q6V0I7
APQLPVVRQYLARFL	RTL10	206	Q7L3V2
PQGFRSTLRAPSLLY	ASCC1	56	Q8N9N2
AITYFLRPNLQPLSE	DPY19L3	226	Q6ZPD9
NLNYLIQLSRPPEFL	CCDC87	226	Q9NVE4
TELPALRYRFNAPIA	ADAMTS10	806	Q9H324
LRYRFNAPIARDSLP	ADAMTS10	811	Q9H324
QQRAYVAPANLPALL	ABCA7	1606	Q8IZY2
ARRNPKNYLSLAPLF	AP3D1	211	O14617
PRPRFSLYLSAQLQI	REC8	61	O95072
RYLPNPSLNAFKDLN	CYP1A1	241	P04798
ILRYLPNPALQRFKA	CYP1A2	241	P05177
YNQLALTARLFRPRL	SHMT2	206	P34897
LRVLSPFAPDYIQRS	INO80	861	Q9ULG1
FAPLLRDNYTLAPNA	SLC10A4	11	Q96EP9
LAPLLLRPQAAARYA	CYP27B1	141	O15528
PHRLQPTYLARVFQA	ABCC10	251	Q5T3U5
VAPVLNPFIYSLRNN	OR1F12P	281	Q8NHA8
ILNPLLNPLIYTFRN	OR4C15	276	Q8NGM1
VFQRQRIPDSYARPL	KMT2C	2016	Q8NEZ4
RDLPPENRASLQYLL	ARHGAP45	896	Q92619
AYLLFGDRPQNLPAA	MAGEB18	41	Q96M61
TIQAKPLQRRPAYFA	FAM149A	551	A5PLN7
ELFRSPAYRQPILIA	SLC2A1	261	P11166
LNRPIVYAQPVAFDR	KIAA1109	3266	Q2LD37
RFLLQQLPPVNYSLL	FAM13B	136	Q9NYF5
TNTLIDPAYLRRGPF	CDH24	341	Q86UP0
PNYPAAARDFLQTFR	MTG1	296	Q9BT17
DFRQRYRILNPSAIP	MYH7B	766	A7E2Y1
RPTLPRFALHDQLFY	PCYOX1L	431	Q8NBM8
PVLENRAYRELRPFS	PNMA6E	311	A0A0J9YXQ4
PANYFHVLRRQILLP	OGDHL	821	Q9ULD0
RLPPLYGDNLDQHFR	POLG	126	P54098
LNLASRLPSYFVRPD	KDM3B	1521	Q7LBC6
LNRNPLTTVEDPYLF	LRRC37B	661	Q96QE4
NRLLVSYDPRIRPNF	GLRB	61	P48167
HNIFNPPIIARYIRL	F8	2156	P00451
VLPRYLFLQNLPSAL	NSUN6	211	Q8TEA1
LHRLPNRDFAFYNPR	ARHGAP32	1681	A7KAX9
PRERYSPFQARVQAL	ADAMTSL5	311	Q6ZMM2
ITPLLNPFIYSLRNR	OR1J4	281	Q8NGS1
LGPQRAASPLRYSLE	DCHS2	1111	Q6V1P9
LRDFFNYLPLSSQDP	PCCB	271	P05166
NALRDLPPYTFANLA	LRRC32	396	Q14392
LPPYTFANLASLQRL	LRRC32	401	Q14392
VPLSEDQLLYLPFRN	ACP3	146	P15309
DQLLYLPFRNCPRFQ	ACP3	151	P15309
LDPSRRRLQQYVPFA	PLEKHG6	46	Q3KR16
YQGALLPREQFAAPL	GATA5	116	Q9BWX5
NNSRLLFNLLPGPYS	CDHR2	616	Q9BYE9
QLASYPQPLLRSFLL	FHIP1A	881	Q05DH4
LNLASRLPNYFVRPD	KDM3A	1081	Q9Y4C1
LPPGYLNLNDAESRR	DOCK11	781	Q5JSL3
LLPFQDRSRPYDTFN	CPEB3	331	Q8NE35
ANLLRSYLNDPISDP	DNAH3	3641	Q8TD57
FASIVLLDQRYARPP	DDX11L8	856	A8MPP1
ELPPAALLFRSARQY	FAM120C	646	Q9NX05
YRAARNRILNPPSLY	HTR1D	221	P28221
TLFPAVPRLLNRIYD	ACSL5	346	Q9ULC5
NYRIPQQRKALLSPF	GRB10	406	Q13322
FPVDNLRASPFLLQY	PRPSAP1	146	Q14558
SLRFPRFYLRQPQHS	LCE7A	61	P0DV60
DLRKAASRNLAFYPP	COLGALT1	241	Q8NBJ5
DIPFRNPNTYDIHRL	GTF2IRD1	846	Q9UHL9
VLSALPNPDDYFLLR	SEC14L6	26	B5MCN3
SFFPVNRLDLQPDLY	SACS	2961	Q9NZJ4
APLYNLPRHRAVNLF	RYR2	3606	Q92736
PQALERYPLAAAAER	IRF2BP2	111	Q7Z5L9
LDQALPSQAFIYRPI	FAM120B	611	Q96EK7
YVNPRALLQLLRAFP	MFNG	146	O00587
LRATYPRTDFALPNQ	LRRC8D	111	Q7L1W4
TPNLSFYRNEIRFLP	OGFR	91	Q9NZT2
RFANYLRNLLPSNDP	MTOR	106	P42345
YIFSGAPLARLNLRN	SLITRK4	491	Q8IW52
YRLRSLHPAQIFNPL	SEL1L3	421	Q68CR1
LLYDVNPPEGFNLRR	POFUT2	46	Q9Y2G5
LARQLIPPLNIAYAA	SLC26A8	116	Q96RN1
RPALQLYDPGARFRA	UPF3A	436	Q9H1J1
ARLLSNPLLQTYLPN	HID1	346	Q8IV36
AAAAYLFQRQLSPTP	NCOR1	1581	O75376
PLNRQATPLLYALAA	SHROOM1	106	Q2M3G4
RQPAELHLFRNYDAP	PLA2G6	591	O60733
PINYRTAARLDAVLP	STARD9	1256	Q9P2P6
FSRYIRPICLPAANA	PRSS8	146	Q16651
ALSQYFRAPIRLPDH	PARVA	196	Q9NVD7
RLFDPEYLNPDSRSN	SANBR	306	Q6NSI8
ALRYFQLPPRAASAA	SHANK1	1081	Q9Y566
RNVRYLTLDIFAGPP	AKR1C1	301	Q04828
RNVRYLTLDIFAGPP	AKR1C2	301	P52895
ARAPQTVYARFLRDP	TULP1	81	O00294
PPRFLLDLRQYLGNS	UST	71	Q9Y2C2
IYPFRRSVSPQLNLV	UNC80	2061	Q8N2C7
RIGPLSPFTNAYRRN	SUPT3H	296	O75486
NPVLPTNRASAYFRL	RPAP3	166	Q9H6T3
KQLALRNALRYFPPD	UROC1	41	Q96N76
RNALRYFPPDVQELL	UROC1	46	Q96N76
AIPVAFLEPTLNRYN	RYR3	3061	Q15413
RLLQPALQRYFLPAD	WDR97	1601	A6NE52
RGNNIRYFILPDSLP	SNRPD1	61	P62314
LLNPSNSARLTPLRY	TENM3	2161	Q9P273
LRFVLPAVLNPRYQF	VWA5A	141	O00534
RFQELLASPAYRASP	SLX9	196	Q9NSI2
AYLAFQDLRNDAPVP	SYNGR4	161	O95473
PPEDNLALLQLYFRT	RPAP1	1276	Q9BWH6
AEYDRPNLLPFLRDS	VPS41	621	P49754
SLTRLPFLYRPRFNA	PRR33	281	A8MZF0
QPQHRAYPRQLFLLT	VWA5B2	436	Q8N398
FARRQLVLLNPYAAL	TTC36	156	A6NLP5
LPLYQYASESAPRLR	SRD5A1	66	P18405
QDNPAYLLLRARFLA	SNAPC4	1356	Q5SXM2
YLPDFFRAPNSTNLI	PIEZO1	1086	Q92508
NDLRYYRLCNDSLPP	XPO6	1106	Q96QU8
AYLRQRPSNPFDRGL	ZDHHC12	221	Q96GR4
TFFHQNYLSLPRPRA	PRR30	96	Q53SZ7
YGFLQPLTRLCQSRP	ZNF318	1671	Q5VUA4
LAQDPYRLAQDPYRL	SON	916	P18583
ELFPRYLLFLRQQPA	USP32	596	Q8NFA0
NADLFQPTSLVRYPR	HECTD3	381	Q5T447
NYSPEDNRFDLRPFL	NADSYN1	661	Q6IA69