Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNB1 CACNB2 CACNB3	9.74e-05	14	132	3	GO:0008331
GeneOntologyMolecularFunction	calcium channel activity	CACNB1 CACNB2 CACNB3 PKDREJ TRPM3 TRPM1	2.18e-04	129	132	6	GO:0005262
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNB1 CACNB2 CACNB3 KCNAB2 PKDREJ TRPM3 KCNJ3 KCNK2 TRPM1	4.67e-04	343	132	9	GO:0005261
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNB1 CACNB2 CACNB3 PKDREJ TRPM3 TRPM1	5.07e-04	151	132	6	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNB1 CACNB2 CACNB3 KCNAB2 KCNJ3 KCNK2	5.25e-04	152	132	6	GO:0022843
GeneOntologyMolecularFunction	potassium channel regulator activity	DPP10 ANK2 KCNAB2 KCNK2	5.49e-04	57	132	4	GO:0015459
GeneOntologyMolecularFunction	ion channel regulator activity	CACNB2 CACNB3 DPP10 ANK2 KCNAB2 KCNK2	7.34e-04	162	132	6	GO:0099106
GeneOntologyMolecularFunction	cytoskeletal protein binding	DLG5 CACNB2 CLSTN3 SPATA31A3 ANK2 POLB SPATA31A7 COBLL1 SPTAN1 SPATA31A6 SPATA31A5 NME8 MYO3A SPATA31A1 BMP10 DIAPH2 USH2A	9.34e-04	1099	132	17	GO:0008092
GeneOntologyMolecularFunction	channel regulator activity	CACNB2 CACNB3 DPP10 ANK2 KCNAB2 KCNK2	1.06e-03	174	132	6	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	CACNB2 CACNB3 DPP10 ANK2 KCNAB2 KCNK2	1.16e-03	177	132	6	GO:0141108
GeneOntologyMolecularFunction	ribosome binding	ZC3H12A RPN2 MTOR NEMF NAA16	1.21e-03	120	132	5	GO:0043022
GeneOntologyMolecularFunction	actin binding	CACNB2 SPATA31A3 SPATA31A7 COBLL1 SPTAN1 SPATA31A6 SPATA31A5 MYO3A SPATA31A1 DIAPH2	1.32e-03	479	132	10	GO:0003779
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNB1 CACNB2 CACNB3 KCNAB2 KCNJ3 KCNK2	1.34e-03	182	132	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNB1 CACNB2 CACNB3 KCNAB2 KCNJ3 KCNK2	1.42e-03	184	132	6	GO:0022832
GeneOntologyBiologicalProcess	cardiac muscle contraction	CACNB2 ZC3H12A ANK2 DSP ADRA1A BMP10 MTOR KCNJ3	1.16e-05	167	131	8	GO:0060048
GeneOntologyBiologicalProcess	action potential	CACNB2 CACNB3 ANK2 DSP KCNAB2 ADRA1A MTOR KCNJ3	4.40e-05	201	131	8	GO:0001508
GeneOntologyBiologicalProcess	regulation of muscle contraction	CACNB1 CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10	4.55e-05	202	131	8	GO:0006937
GeneOntologyBiologicalProcess	striated muscle contraction	CACNB2 ZC3H12A ANK2 DSP ADRA1A BMP10 MTOR KCNJ3	7.53e-05	217	131	8	GO:0006941
GeneOntologyBiologicalProcess	positive regulation of inhibitory synapse assembly	SEMA4D CLSTN3	1.20e-04	3	131	2	GO:1905704
GeneOntologyBiologicalProcess	heart contraction	CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10 MTOR KCNJ3	1.23e-04	298	131	9	GO:0060047
GeneOntologyBiologicalProcess	regulation of heart rate by cardiac conduction	CACNB2 ANK2 DSP KCNJ3	1.31e-04	41	131	4	GO:0086091
GeneOntologyBiologicalProcess	heart process	CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10 MTOR KCNJ3	1.62e-04	309	131	9	GO:0003015
GeneOntologyBiologicalProcess	regulation of action potential	CACNB3 ANK2 DSP KCNAB2 ADRA1A	1.67e-04	81	131	5	GO:0098900
GeneOntologyBiologicalProcess	regulation of heart rate	CACNB2 ANK2 DSP NMU ADRA1A KCNJ3	1.76e-04	129	131	6	GO:0002027
GeneOntologyBiologicalProcess	regulation of heart contraction	CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10 KCNJ3	1.95e-04	249	131	8	GO:0008016
GeneOntologyBiologicalProcess	regulation of muscle system process	CACNB1 CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10 MTOR	1.96e-04	317	131	9	GO:0090257
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell communication	CACNB2 ANK2 KCNJ3	2.25e-04	19	131	3	GO:0086066
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell signaling	CACNB2 ANK2 KCNJ3	2.25e-04	19	131	3	GO:0086026
GeneOntologyBiologicalProcess	atrial cardiac muscle cell action potential	CACNB2 ANK2 KCNJ3	2.25e-04	19	131	3	GO:0086014
GeneOntologyBiologicalProcess	muscle contraction	CACNB1 CACNB2 ZC3H12A ANK2 DSP NMU ADRA1A BMP10 MTOR KCNJ3	2.42e-04	400	131	10	GO:0006936
GeneOntologyBiologicalProcess	regulation of cardiac muscle contraction	ZC3H12A ANK2 DSP ADRA1A BMP10	2.59e-04	89	131	5	GO:0055117
GeneOntologyCellularComponent	T-tubule	CACNB1 CACNB2 CACNB3 ANK2 ADRA1A KCNJ3	1.03e-05	79	131	6	GO:0030315
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNB1 CACNB2 CACNB3	5.08e-05	12	131	3	GO:1990454
GeneOntologyCellularComponent	secretory granule	DOCK2 GPI SPATA31A3 ANPEP SFTPB DSP SPATA31A7 SPTAN1 UBR4 KCNAB2 SPATA31A6 SPATA31A5 PIKFYVE PTPRB SPATA31A1 ATP11B ARHGAP45 DYNC1H1	6.32e-05	1014	131	18	GO:0030141
GeneOntologyCellularComponent	secretory vesicle	DOCK2 GPI SPATA31A3 ANPEP SFTPB DSP SPATA31A7 SPTAN1 UBR4 KCNAB2 SPATA31A6 SPATA31A5 DDC PIKFYVE PTPRB SPATA31A1 ATP11B ARHGAP45 DYNC1H1	2.82e-04	1246	131	19	GO:0099503
MousePheno	absent organized vascular network	PTPRB PAXIP1 KDR	1.77e-05	8	97	3	MP:0000263
MousePheno	embryonic growth arrest	UBR4 HLCS CHD8 HORMAD1 PIKFYVE PTPRB HMCN1 BMP10 MTOR PAXIP1 CDK11B	2.71e-05	346	97	11	MP:0001730
MousePheno	abnormal embryo development	DLG5 DSP POLB SPTAN1 UBR4 HLCS CHD8 GRHL2 HORMAD1 DDC FANCA PIKFYVE PTPRB HMCN1 BMP10 MTOR AMOT PAXIP1 KDR RPRD2 ALAS1 CDK11B WDFY3	4.74e-05	1370	97	23	MP:0001672
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	8.51e-07	12	123	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	8.51e-07	12	123	4	IPR027970
Domain	VDCC_L_bsu	CACNB1 CACNB2 CACNB3	1.11e-06	4	123	3	IPR000584
Domain	VGCC_beta4Aa_N	CACNB1 CACNB2 CACNB3	1.11e-06	4	123	3	PF12052
Domain	Guanylate_kin	CACNB1 DLG5 CACNB2 CACNB3	2.39e-05	26	123	4	PF00625
Domain	GK/Ca_channel_bsu	CACNB1 DLG5 CACNB2 CACNB3	2.39e-05	26	123	4	IPR008145
Domain	Guanylate_kin-like_dom	CACNB1 DLG5 CACNB2 CACNB3	2.39e-05	26	123	4	IPR008144
Domain	GuKc	CACNB1 DLG5 CACNB2 CACNB3	2.39e-05	26	123	4	SM00072
Domain	FYVE	ANKFY1 PLEKHF2 PIKFYVE WDFY3	3.74e-05	29	123	4	PF01363
Domain	FYVE	ANKFY1 PLEKHF2 PIKFYVE WDFY3	3.74e-05	29	123	4	SM00064
Domain	Znf_FYVE-rel	ANKFY1 PLEKHF2 PIKFYVE WDFY3	7.13e-05	34	123	4	IPR017455
Domain	Znf_FYVE	ANKFY1 PLEKHF2 PIKFYVE WDFY3	1.11e-04	38	123	4	IPR000306
Domain	ZF_FYVE	ANKFY1 PLEKHF2 PIKFYVE WDFY3	1.36e-04	40	123	4	PS50178
Domain	TRPM_tetra	TRPM3 TRPM1	2.56e-04	4	123	2	PF16519
Domain	TRPM_tetra	TRPM3 TRPM1	2.56e-04	4	123	2	IPR032415
Domain	-	CLSTN3 FAT1 CNTNAP5 WDFY3 USH2A	4.12e-04	95	123	5	2.60.120.200
Domain	ARM-type_fold	KPNA4 DOCK2 UBR4 MTOR DIAPH2 MMS19 PRKDC WDFY3 KPNA3	4.13e-04	339	123	9	IPR016024
Domain	FATC	MTOR PRKDC	4.25e-04	5	123	2	PF02260
Domain	SH3	DOCK2 CACNB1 DLG5 CACNB2 CACNB3 SH3RF1 SPTAN1	5.74e-04	216	123	7	SM00326
Domain	SH3	DOCK2 CACNB1 DLG5 CACNB2 CACNB3 SH3RF1 SPTAN1	5.74e-04	216	123	7	PS50002
Domain	BRK	CHD8 CHD6	6.34e-04	6	123	2	SM00592
Domain	BRK_domain	CHD8 CHD6	6.34e-04	6	123	2	IPR006576
Domain	FAT	MTOR PRKDC	6.34e-04	6	123	2	PS51189
Domain	FATC	MTOR PRKDC	6.34e-04	6	123	2	PS51190
Domain	FAT	MTOR PRKDC	6.34e-04	6	123	2	PF02259
Domain	PIK-rel_kinase_FAT	MTOR PRKDC	6.34e-04	6	123	2	IPR003151
Domain	FATC_dom	MTOR PRKDC	6.34e-04	6	123	2	IPR003152
Domain	PIK_FAT	MTOR PRKDC	6.34e-04	6	123	2	IPR014009
Domain	BRK	CHD8 CHD6	6.34e-04	6	123	2	PF07533
Domain	FATC	MTOR PRKDC	6.34e-04	6	123	2	SM01343
Domain	SH3_domain	DOCK2 CACNB1 DLG5 CACNB2 CACNB3 SH3RF1 SPTAN1	6.40e-04	220	123	7	IPR001452
Domain	Arm_3	KPNA4 KPNA3	8.84e-04	7	123	2	PF16186
Domain	Importing_su_alpha	KPNA4 KPNA3	8.84e-04	7	123	2	IPR024931
Domain	IBB	KPNA4 KPNA3	8.84e-04	7	123	2	PF01749
Domain	Arm_3	KPNA4 KPNA3	8.84e-04	7	123	2	IPR032413
Domain	IBB	KPNA4 KPNA3	1.17e-03	8	123	2	PS51214
Domain	Importin-a_IBB	KPNA4 KPNA3	1.50e-03	9	123	2	IPR002652
Domain	LAM_G_DOMAIN	FAT1 CNTNAP5 USH2A	1.99e-03	38	123	3	PS50025
Domain	ARM-like	KPNA4 DOCK2 MTOR MMS19 PRKDC WDFY3 KPNA3	2.09e-03	270	123	7	IPR011989
Domain	Laminin_G_2	FAT1 CNTNAP5 USH2A	2.31e-03	40	123	3	PF02210
Domain	Znf_FYVE_PHD	ANKFY1 PLEKHF2 PIKFYVE PHF3 WDFY3	2.90e-03	147	123	5	IPR011011
Domain	LamG	FAT1 CNTNAP5 USH2A	3.03e-03	44	123	3	SM00282
Domain	ConA-like_dom	CLSTN3 FAT1 CNTNAP5 MAMDC2 WDFY3 USH2A	3.31e-03	219	123	6	IPR013320
Domain	-	KPNA4 MTOR MMS19 PRKDC WDFY3 KPNA3	3.53e-03	222	123	6	1.25.10.10
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DYNC1H1	3.72e-03	14	123	2	IPR024317
Domain	Dynein_HC_stalk	DNAH7 DYNC1H1	3.72e-03	14	123	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH7 DYNC1H1	3.72e-03	14	123	2	IPR013602
Domain	DHC_N2	DNAH7 DYNC1H1	3.72e-03	14	123	2	PF08393
Domain	P_typ_ATPase_c	ATP9B ATP11B	3.72e-03	14	123	2	IPR032630
Domain	P-type_ATPase_N	ATP9B ATP11B	3.72e-03	14	123	2	IPR032631
Domain	P-type_ATPase_IV	ATP9B ATP11B	3.72e-03	14	123	2	IPR006539
Domain	MT	DNAH7 DYNC1H1	3.72e-03	14	123	2	PF12777
Domain	AAA_8	DNAH7 DYNC1H1	3.72e-03	14	123	2	PF12780
Domain	PhoLip_ATPase_C	ATP9B ATP11B	3.72e-03	14	123	2	PF16212
Domain	PhoLip_ATPase_N	ATP9B ATP11B	3.72e-03	14	123	2	PF16209
Domain	DHC_fam	DNAH7 DYNC1H1	4.27e-03	15	123	2	IPR026983
Domain	Dynein_heavy	DNAH7 DYNC1H1	4.27e-03	15	123	2	PF03028
Domain	PI3/4_kinase_CS	MTOR PRKDC	4.27e-03	15	123	2	IPR018936
Domain	Dynein_heavy_dom	DNAH7 DYNC1H1	4.27e-03	15	123	2	IPR004273
Domain	-	MTOR PRKDC	4.86e-03	16	123	2	1.10.1070.11
Domain	PI3Kc	MTOR PRKDC	4.86e-03	16	123	2	SM00146
Domain	Thioredoxin_CS	NME8 DNAJC10	5.48e-03	17	123	2	IPR017937
Domain	PI3_PI4_kinase	MTOR PRKDC	6.14e-03	18	123	2	PF00454
Domain	PI3_4_KINASE_1	MTOR PRKDC	6.14e-03	18	123	2	PS00915
Domain	PI3_4_KINASE_2	MTOR PRKDC	6.14e-03	18	123	2	PS00916
Domain	PI3/4_kinase_cat_dom	MTOR PRKDC	6.14e-03	18	123	2	IPR000403
Domain	PI3_4_KINASE_3	MTOR PRKDC	6.14e-03	18	123	2	PS50290
Pathway	WP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL	CACNB1 CACNB3 MTOR KCNJ3 PCDH19 KDR	6.91e-06	73	90	6	MM16641
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB1 CACNB2 CACNB3	4.00e-05	11	90	3	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB1 CACNB2 CACNB3	4.00e-05	11	90	3	M26913
Pathway	REACTOME_NEUTROPHIL_DEGRANULATION	DOCK2 GPI ANPEP DSP SPTAN1 UBR4 KCNAB2 PTPRB ATP11B ARHGAP45 DYNC1H1	2.25e-04	478	90	11	M27620
Pathway	KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING	CACNB1 CACNB2 CACNB3	3.08e-04	21	90	3	M47950
Pathway	KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING	CACNB1 CACNB2 CACNB3	3.08e-04	21	90	3	M47949
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	4.54e-12	6	133	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	4.54e-12	6	133	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	3.04e-08	24	133	5	32212159
Pubmed	Mice with cardiac-specific sequestration of the beta-subunit of the L-type calcium channel.	CACNB1 CACNB2 CACNB3	5.47e-08	3	133	3	12054671
Pubmed	Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits.	CACNB1 CACNB2 CACNB3	2.18e-07	4	133	3	18535142
Pubmed	Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.	CACNB1 CACNB2 CACNB3	2.18e-07	4	133	3	19996312
Pubmed	Mutations of calcium channel beta subunit genes in mice.	CACNB1 CACNB2 CACNB3	2.18e-07	4	133	3	10494839
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KPNA4 SEMA4D CLSTN3 ANK2 DSP SPTAN1 UBR4 KCNAB2 HLCS TTC27 STAMBP SACS NEMF CHD6 PRKDC WDFY3 EXOC7 DYNC1H1 KPNA3	4.72e-07	1285	133	19	35914814
Pubmed	Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.	CACNB1 CACNB2 CACNB3	5.44e-07	5	133	3	11980879
Pubmed	Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.	CACNB1 CACNB2 CACNB3	5.44e-07	5	133	3	19723630
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNB1 CACNB2 CACNB3	1.08e-06	6	133	3	10328888
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CACNB2 CACNB3 ANK2 SPTAN1 KCNAB2 SACS MTOR PHF3 DYNC1H1	1.47e-06	281	133	9	28706196
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ANKFY1 CHD8 BIRC6 PHF3 AMOT RPRD2 CHD6 WDFY3	2.65e-06	225	133	8	12168954
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	COBLL1 DNAH7 PIKFYVE ATP11B NINL WDFY3	2.78e-06	102	133	6	10231032
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DOCK2 GPI CACNB2 GALK1 DSP RPN2 SPTAN1 UBR4 RTN3 CHD8 HIVEP3 PRKDC ALDH1A1 DYNC1H1	2.81e-06	807	133	14	30575818
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLSTN3 ANKFY1 FRMPD4 ZHX2 USP19 YEATS2 PHF3 PCDH19 CHD6 DYNC1H1	4.06e-06	407	133	10	12693553
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ANKFY1 DSP UBR4 ATG2B TTC27 CHD8 BIRC6 YEATS2 AMOT CHD6	5.13e-06	418	133	10	34709266
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNB1 CACNB2 CACNB3	8.82e-06	11	133	3	18809727
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	GALK1 DSP SPTAN1 ATG2B CHD8 YEATS2 PHF3 AMOT RPRD2 PRKDC DYNC1H1	9.15e-06	549	133	11	38280479
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KPNA4 ANK2 PCDHGB3 DSP RPN2 DTNB SPTAN1 ECD UBR4 SRBD1 DNAJC10 SACS TNN KDR CHD6 PRKDC ALDH1A1 CCDC191	1.02e-05	1442	133	18	35575683
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	CHD8 HIVEP3 WDFY3	1.17e-05	12	133	3	27824329
Pubmed	Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.	MTOR PRKDC	1.45e-05	2	133	2	27235137
Pubmed	Distribution of voltage-dependent calcium channel beta subunits in the hippocampus of patients with temporal lobe epilepsy.	CACNB1 CACNB2	1.45e-05	2	133	2	10465427
Pubmed	Non-viral reprogramming of fibroblasts into induced pluripotent stem cells by Sleeping Beauty and piggyBac transposons.	PGBD1 PRKDC	1.45e-05	2	133	2	24928388
Pubmed	Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.	PTPRB KDR	1.45e-05	2	133	2	19136612
Pubmed	DNA-PK, Nuclear mTOR, and the Androgen Pathway in Prostate Cancer.	MTOR PRKDC	1.45e-05	2	133	2	32209447
Pubmed	Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line.	CACNB1 CACNB2	1.45e-05	2	133	2	10066897
Pubmed	Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection.	KPNA4 KPNA3	1.45e-05	2	133	2	32320654
Pubmed	Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization.	CACNB1 CACNB2	1.45e-05	2	133	2	14762176
Pubmed	Modified cardiovascular L-type channels in mice lacking the voltage-dependent Ca2+ channel beta3 subunit.	CACNB2 CACNB3	1.45e-05	2	133	2	12920136
Pubmed	Regnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolism.	ZC3H12A MTOR	1.45e-05	2	133	2	30297433
Pubmed	Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.	TRPM3 TRPM1	1.45e-05	2	133	2	21278253
Pubmed	Genetic loss of importin α4 causes abnormal sperm morphology and impacts on male fertility in mouse.	KPNA4 KPNA3	1.45e-05	2	133	2	33058343
Pubmed	Quantitative and electron microscopic studies of sensory ganglion cells of the Sprawling mouse.	GPI DYNC1H1	1.45e-05	2	133	2	894335
Pubmed	Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.	CACNB2 CACNB3	1.45e-05	2	133	2	8494331
Pubmed	Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB.	KPNA4 KPNA3	1.45e-05	2	133	2	28179530
Pubmed	VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.	PTPRB KDR	1.45e-05	2	133	2	23575676
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNB1 CACNB2 CACNB3 KCNAB2 KCNJ3 KCNK2	1.65e-05	139	133	6	16985003
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	GPI ANKFY1 GALK1 DSP SPTAN1 UBR4 TTC27 CHD8 SRBD1 BIRC6 AARSD1 MMS19 PRKDC HSP90AB2P WDFY3 DYNC1H1 KPNA3	1.69e-05	1353	133	17	29467282
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CBLL1 DLG5 DSP RPN2 SPTAN1 AARSD1 DNAJC10 SACS MAMDC2 NEMF CHD6 PRKDC CDK11B DYNC1H1 KPNA3	1.78e-05	1082	133	15	38697112
Pubmed	A human MAP kinase interactome.	KPNA4 SH3RF1 DSP COBLL1 SPTAN1 CHD8 STAMBP DIAPH2 CHD6 PRKDC	1.89e-05	486	133	10	20936779
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CBLL1 CACNB1 CACNB2 ANKFY1 ANK2 SPTAN1 UBR4 KCNAB2 CHD8 CNTNAP5 MTOR DIAPH2 WDFY3 DYNC1H1	2.05e-05	963	133	14	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK2 SH3RF1 COBLL1 BIRC6 PIKFYVE HIVEP3 TRPM3 SACS EXOC7 PCYOX1	2.13e-05	493	133	10	15368895
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SH3RF1 UBR4 CHD8 BIRC6 FANCA PIKFYVE HIVEP3 FAT1 MTOR PAXIP1 DIAPH2 NINL PRKDC WDFY3 DYNC1H1	2.27e-05	1105	133	15	35748872
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNB1 CACNB2 CACNB3	2.41e-05	15	133	3	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNB1 CACNB2 CACNB3	2.41e-05	15	133	3	24453333
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	GPI DLG5 DSP RPN2 RPP40 UBR4 MMS19 PRKDC DYNC1H1	2.45e-05	399	133	9	37536630
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	PCDHGB3 DSP TOPAZ1 UBR4 BIRC6 FANCA ADRA1A TRPM3 AMOT CHD6 PRKDC DYNC1H1	2.75e-05	736	133	12	29676528
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	KPNA4 DSP RPN2 SPTAN1 UBR4 RTN3 ERMP1 BIRC6 FAT1 DNAJC10 NEMF MMS19 PRKDC DYNC1H1 PCYOX1 KPNA3	3.79e-05	1297	133	16	33545068
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DLG5 POLB SPTAN1 ECD ATG2B ZC3HC1 SRBD1 AMOT CCDC138 PAXIP1 CHD6	4.01e-05	645	133	11	25281560
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	GPI GALK1 DSP SPTAN1 UBR4 TTC27 MTOR MMS19 PRKDC EXOC7 DYNC1H1	4.13e-05	647	133	11	26618866
Pubmed	Defining the membrane proteome of NK cells.	DOCK2 GPI GALK1 RPN2 UBR4 ERMP1 BIRC6 DNAJC10 ATP11B MTOR MMS19 PRKDC EXOC7 ARHGAP45 DYNC1H1	4.28e-05	1168	133	15	19946888
Pubmed	PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI-Resistant Metastatic Clear Cell Renal Cell Carcinoma.	MTOR KDR	4.34e-05	3	133	2	35240013
Pubmed	Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1.	KPNA4 KPNA3	4.34e-05	3	133	2	22665369
Pubmed	PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.	PIKFYVE MTOR	4.34e-05	3	133	2	27623384
Pubmed	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.	PTPRB KDR	4.34e-05	3	133	2	10557082
Pubmed	Karyopherin α 3 and karyopherin α 4 proteins mediate the nuclear import of methyl-CpG binding protein 2.	KPNA4 KPNA3	4.34e-05	3	133	2	26245896
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD6	4.34e-05	3	133	2	28533432
Pubmed	Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts.	MTOR KDR	4.34e-05	3	133	2	24952635
Pubmed	Interaction of tissue transglutaminase with nuclear transport protein importin-alpha3.	KPNA4 KPNA3	4.34e-05	3	133	2	10100610
Pubmed	Direct Evidence of Target Inhibition with Anti-VEGF, EGFR, and mTOR Therapies in a Clinical Model of Wound Healing.	MTOR KDR	4.34e-05	3	133	2	25878330
Pubmed	Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.	CACNB1 CACNB3	4.34e-05	3	133	2	22737983
Pubmed	Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit.	CACNB2 PRKDC	4.34e-05	3	133	2	10567342
Pubmed	Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway.	PRLHR MTOR	4.34e-05	3	133	2	23284171
Pubmed	Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels.	CACNB2 PRKDC	4.34e-05	3	133	2	10441130
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	GALK1 SPTAN1 UBR4 CHD8 PHF3 MMS19 PRKDC DYNC1H1	4.42e-05	332	133	8	32786267
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	DSP RPN2 SPTAN1 DMXL1 HIVEP3 PTPRB PRKDC DYNC1H1	4.51e-05	333	133	8	32665550
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	DLG5 DSP SPTAN1 ECD ATG2B PRKDC DYNC1H1	6.10e-05	256	133	7	33397691
Pubmed	Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.	DSP CHD8 AMOT DYNC1H1	6.90e-05	57	133	4	38223760
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	GPI DSP RPN2 SPTAN1 COMMD2 PRKDC HSP90AB2P CDK11B DYNC1H1	7.71e-05	463	133	9	34901782
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	DLG5 DSP HLCS YEATS2 ZNF776 RPRD2	7.94e-05	184	133	6	32908313
Pubmed	Identification of Modifier Genes in a Mouse Model of Gaucher Disease.	DPP10 PLEKHF2 MAMDC2	7.98e-05	22	133	3	27568557
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	GPI SPTAN1 ATG2B ERMP1 PRKDC ALDH1A1 DYNC1H1	8.13e-05	268	133	7	33024031
Pubmed	Importin α3 regulates chronic pain pathways in peripheral sensory neurons.	KPNA4 KPNA3	8.67e-05	4	133	2	32792398
Pubmed	The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).	CACNB1 CACNB2	8.67e-05	4	133	2	16636205
Pubmed	MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.	KPNA4 KPNA3	8.67e-05	4	133	2	29370303
Pubmed	Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex.	SPTAN1 FANCA	8.67e-05	4	133	2	10551855
Pubmed	Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception.	TRPM3 TRPM1	8.67e-05	4	133	2	22211741
Pubmed	Hydrogen sulfide promotes angiogenesis by downregulating miR-640 via the VEGFR2/mTOR pathway.	MTOR KDR	8.67e-05	4	133	2	26879375
Pubmed	Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.	SPTAN1 FANCA	8.67e-05	4	133	2	12571280
Pubmed	The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression.	MTOR KDR	8.67e-05	4	133	2	24952732
Pubmed	Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression.	KPNA4 KPNA3	8.67e-05	4	133	2	19710421
Pubmed	mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.	MTOR PRKDC	8.67e-05	4	133	2	16221682
Pubmed	Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1).	KCNJ3 KCNK2	8.67e-05	4	133	2	9506712
Pubmed	Over-expression of DNA-PKcs in renal cell carcinoma regulates mTORC2 activation, HIF-2α expression and cell proliferation.	MTOR PRKDC	8.67e-05	4	133	2	27412013
Pubmed	Subcellular distribution of importins correlates with germ cell maturation.	KPNA4 KPNA3	8.67e-05	4	133	2	17654710
Pubmed	Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family.	KPNA4 KPNA3	8.67e-05	4	133	2	9395085
Pubmed	Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.	ANK2 SPTAN1	8.67e-05	4	133	2	14593108
Pubmed	Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype.	CACNB1 CACNB2	8.67e-05	4	133	2	1309651
Pubmed	Decoding the fine-scale structure of a breast cancer genome and transcriptome.	GRHL2 STAMBP CCDC138	9.15e-05	23	133	3	16461635
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	DSP SPTAN1 UBR4 CHD8 DMXL1 DNAJC10 NEMF CHD6 KPNA3	9.36e-05	475	133	9	31040226
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	GPI DSP RPN2 SPTAN1 AMOT PRKDC DYNC1H1	1.27e-04	288	133	7	31501420
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	GALK1 RPN2 SPTAN1 ECD UBR4 TTC27 TNFRSF10A DNAJC10 MTOR COMMD2 MMS19 PRKDC HSP90AB2P EXOC7 DYNC1H1 KPNA3	1.29e-04	1440	133	16	30833792
Pubmed	Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links.	SPTAN1 FANCA	1.44e-04	5	133	2	11401546
Pubmed	A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.	ANK2 SPTAN1	1.44e-04	5	133	2	22632975
Pubmed	Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases.	CACNB1 CACNB2	1.44e-04	5	133	2	14623965
Pubmed	Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.	KPNA4 KPNA3	1.44e-04	5	133	2	19961612
Pubmed	Genetic interaction between DNA polymerase beta and DNA-PKcs in embryogenesis and neurogenesis.	POLB PRKDC	1.44e-04	5	133	2	15647757
Pubmed	Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.	KPNA4 KPNA3	1.44e-04	5	133	2	17981117
Pubmed	Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature.	PTPRB KDR	1.44e-04	5	133	2	28542220
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	2.27e-04	8	132	2	chr9q12
Cytoband	9q21.12	TRPM3 MAMDC2	3.64e-04	10	132	2	9q21.12
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB1 DLG5 CACNB2 CACNB3	7.89e-06	26	90	4	904
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ANKFY1 PLEKHF2 PIKFYVE WDFY3	1.63e-05	31	90	4	81
GeneFamily	Calcium voltage-gated channel subunits	CACNB1 CACNB2 CACNB3	2.85e-04	26	90	3	253
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP3 BMP10	1.31e-03	11	90	2	455
GeneFamily	Potassium voltage-gated channel regulatory subunits\|DASH family	DPP10 KCNAB2	2.47e-03	15	90	2	858
GeneFamily	ATPase phospholipid transporting	ATP9B ATP11B	2.47e-03	15	90	2	1210
GeneFamily	Cadherin related	CLSTN3 FAT1	3.17e-03	17	90	2	24
GeneFamily	Armadillo repeat containing\|Importins	KPNA4 KPNA3	3.56e-03	18	90	2	596
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	DOCK2 CACNB2 LRRIQ3 ANKFY1 SH3RF1 DTNB CHD8 BIRC6 HORMAD1 DNAH7 DMXL1 ENO4 ATP11B HMCN1 SACS ALDH1A1 WDFY3	4.77e-06	795	126	17	gudmap_developingGonad_e16.5_ovary_1000
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 COBLL1 CPM GRHL2 DNAH7 FAT1 KCNJ3 NINL	1.14e-07	194	131	8	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D ERMP1 GRHL2 DNAH7 FAT1 KCNJ3 WDFY3	1.49e-06	189	131	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	COVID-19_Mild-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	LRRIQ3 PCDHGB3 CCDC168 GRHL2 ENO4 HMCN1	1.66e-06	122	131	6	2aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3 TRPM3	1.71e-06	193	131	7	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 GRHL2 DNAH7 FAT1 TRPM3 KCNJ3 NINL	1.77e-06	194	131	7	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D COBLL1 GRHL2 DNAH7 FAT1 KCNJ3 NINL	1.89e-06	196	131	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D ANK2 COBLL1 GRHL2 DNAH7 KCNJ3 NINL	1.89e-06	196	131	7	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	356C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 LRRIQ3 DSP EVI2B CCDC168 PCDH19	7.69e-06	159	131	6	299e2162a82e31196d7f3a110c2db622349edfff
ToppCell	356C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 LRRIQ3 DSP EVI2B CCDC168 PCDH19	7.69e-06	159	131	6	0a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4D HLCS FANCA HMCN1 TRPM3 WDFY3	1.16e-05	171	131	6	e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB KCNAB2 CPM YEATS2 KCNK2 PRKDC	1.33e-05	175	131	6	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ZC3H12A ANKFY1 COBLL1 ECD GRHL2 ENO4	1.37e-05	176	131	6	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SFTPB TRPM3 PHF3 MAMDC2 ALDH1A1	1.42e-05	177	131	6	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DLG5 CLSTN3 APOBEC3D ERMP1 NMU ALAS1	1.51e-05	179	131	6	d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SH3RF1 HIVEP3 ADRA1A MAMDC2 ALDH1A1	1.56e-05	180	131	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CACNB2 ANK2 SFTPB BMP3 FAT1 MAMDC2	1.82e-05	185	131	6	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	1.99e-05	188	131	6	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	1.99e-05	188	131	6	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DTNB COBLL1 GRHL2 TRPM3 KCNJ3 ALAS1	2.11e-05	190	131	6	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D COBLL1 ERMP1 GRHL2 DNAH7 FAT1	2.18e-05	191	131	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP COBLL1 CPM GRHL2 NMU MYO3A	2.24e-05	192	131	6	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANK2 COBLL1 CPM GRHL2 DNAH7 BMP3	2.24e-05	192	131	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.24e-05	192	131	6	b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.24e-05	192	131	6	450baeb5c3df7a9445472530002ce38f177a333c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP COBLL1 CPM GRHL2 MYO3A ALDH1A1	2.24e-05	192	131	6	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.31e-05	193	131	6	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 COBLL1 DNAH7 FAT1 TRPM3 NINL	2.31e-05	193	131	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSP CPM GRHL2 NMU BMP3 TRPM3	2.38e-05	194	131	6	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.38e-05	194	131	6	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP COBLL1 CPM GRHL2 DNAH7 BMP3	2.38e-05	194	131	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.45e-05	195	131	6	d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.45e-05	195	131	6	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP CPM GRHL2 NMU BMP3	2.45e-05	195	131	6	ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 COBLL1 GRHL2 DNAH7 KCNJ3 NINL	2.45e-05	195	131	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	PCW_10-12-Epithelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.52e-05	196	131	6	9bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP CPM GRHL2 NMU BMP3	2.52e-05	196	131	6	7b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCell	PCW_13-14-Epithelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.67e-05	198	131	6	48eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB2 ANK2 PAMR1 HMCN1 MAMDC2 TNN	2.67e-05	198	131	6	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB DSP COBLL1 CPM GRHL2 BMP3	2.67e-05	198	131	6	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTAN1 BIRC6 PTPRB HMCN1 DIAPH2 KDR	2.82e-05	200	131	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19-kidney-Epithelial_Doublet\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP10 TOPAZ1 SPATA31A6 CNTNAP5 TRPM1	4.15e-05	130	131	5	1ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell	PBMC-Mild-cDC_7\|Mild / Compartment, Disease Groups and Clusters	CACNB3 TRGV9 GRHL2 MAMDC2 NINL	6.31e-05	142	131	5	58f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEMA4D EVI2B ATP9B CCDC168 NME8	6.31e-05	142	131	5	f720f13b339589fa924a42e89393e5db0b26300b
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP10 FRMPD4 NME8 CNTNAP5 USH2A	6.97e-05	145	131	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D175\|Adult / Lineage, Cell type, age group and donor	LRRIQ3 FAT1 HMCN1 AMOT ZNF415	7.68e-05	148	131	5	012845b10850bbc67814da247ee5a69f6d631eaa
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNB2 PRLHR DDC TRPM3 GGTLC3	9.55e-05	155	131	5	498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EVI2B HORMAD1 ZNF182 PTPRB DNAJC10	1.04e-04	158	131	5	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN3 MYO3A KCNK2 ALAS1 ALDH1A1	1.14e-04	161	131	5	c4970501c038ed36de447da70eabff020ad78713
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN3 MYO3A KCNK2 ALAS1 ALDH1A1	1.14e-04	161	131	5	41a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COBLL1 DDC PTPRB HMCN1 KDR	1.24e-04	164	131	5	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COBLL1 DDC PTPRB HMCN1 KDR	1.24e-04	164	131	5	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COBLL1 DDC PTPRB HMCN1 KDR	1.32e-04	166	131	5	27af6c906cff1d40d134f0386db7708869691121
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRLHR DSP DDC GGTLC3 USH2A	1.32e-04	166	131	5	afba41e15478053f11815acf568d29187de75492
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DPP10 DSP CCDC168 DDC BMP3	1.47e-04	170	131	5	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	390C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	LRRIQ3 POLB COBLL1 TTC27 NME8	1.73e-04	176	131	5	aab9603b7943b7f7243eb6190ebba998566196f3
ToppCell	NS-moderate-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DPP10 ANK2 SFTPB CNTNAP5 MAMDC2	1.78e-04	177	131	5	99500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 KCNAB2 TRGV9 EVI2B ARHGAP45	1.87e-04	179	131	5	874a9afa91774221c9c1775aa4968ba0aea7b554
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SH3RF1 ADRA1A MAMDC2 ALDH1A1	1.92e-04	180	131	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SH3RF1 ADRA1A MAMDC2 ALDH1A1	1.97e-04	181	131	5	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DTNB COBLL1 GRHL2 TRPM3 KCNJ3	1.97e-04	181	131	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB DSP GRHL2 BMP3 TRPM3	2.02e-04	182	131	5	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 BMP3 ADRA1A MAMDC2 ALDH1A1	2.02e-04	182	131	5	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 BMP3 ADRA1A MAMDC2 ALDH1A1	2.02e-04	182	131	5	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 GRHL2 TRPM3 KCNJ3 ALAS1	2.07e-04	183	131	5	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D ERMP1 GRHL2 FAT1 WDFY3	2.07e-04	183	131	5	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 FAT1 HMCN1 TRPM3 USH2A	2.13e-04	184	131	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 FAT1 HMCN1 TRPM3 USH2A	2.13e-04	184	131	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 FAT1 HMCN1 TRPM3 USH2A	2.13e-04	184	131	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	3beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CACNB3 ANK2 PAMR1 DDC HMCN1	2.18e-04	185	131	5	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	9aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	42939b294ea3e871274d8b73124c850dc1904fd2
ToppCell	Severe_COVID-19-Myeloid-transitional_Macro\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNAB2 RTN3 CPM MAMDC2 ALDH1A1	2.18e-04	185	131	5	7a3612520ae4f0cd61480eadba31eecce001419d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D GRHL2 FAT1 KCNJ3 WDFY3	2.23e-04	186	131	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D CPM ZHX2 DNAH7 TRPM3	2.23e-04	186	131	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SH3RF1 TRGV9 FSIP2 HMCN1	2.25e-04	101	131	4	657d3994b93e2fbb1ff96f701ff2ea6665e5a15c
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	BBS1 ZNF776 MTOR MAMDC2 CCDC191	2.29e-04	187	131	5	0e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	DPP10 SFTPB DSP FAT1 KDR	2.29e-04	187	131	5	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPI CACNB2 ANK2 CPM NINL	2.29e-04	187	131	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DSP CPM GRHL2 NMU BMP3	2.29e-04	187	131	5	c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell	LPS-antiTNF-Epithelial_alveolar\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB DSP GRHL2 BMP3 TRPM3	2.29e-04	187	131	5	201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	SH3RF1 SFTPB COBLL1 CPM GRHL2	2.29e-04	187	131	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 ANPEP FAT1 TRPM3 WDFY3	2.29e-04	187	131	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FRMPD4 ANPEP PTPRB KDR ALDH1A1	2.29e-04	187	131	5	03de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DTNB COBLL1 GRHL2 CNTNAP5 TRPM3	2.35e-04	188	131	5	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 DSP ERMP1 GRHL2 TNN	2.35e-04	188	131	5	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 GRHL2 TRPM3 KCNJ3 ALAS1	2.35e-04	188	131	5	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP COBLL1 CPM GRHL2 ALDH1A1	2.41e-04	189	131	5	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CACNB1 CACNB2 GALK1 MTOR DYNC1H1	2.41e-04	189	131	5	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 GRHL2 TRPM3 KCNJ3 ALAS1	2.41e-04	189	131	5	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CACNB2 CPM HIVEP3 BMP3 HMCN1	2.41e-04	189	131	5	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP COBLL1 CPM GRHL2 BMP3	2.41e-04	189	131	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAMR1 BMP3 ADRA1A MAMDC2 ALDH1A1	2.41e-04	189	131	5	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DTNB COBLL1 GRHL2 TRPM3 KCNJ3	2.41e-04	189	131	5	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	POLB COBLL1 DMXL1 PIKFYVE SACS	2.47e-04	190	131	5	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	DPP10 SFTPB DSP FAT1 KDR	2.47e-04	190	131	5	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ERMP1 CPM GRHL2 HIVEP3	2.47e-04	190	131	5	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
Drug	gadolinium	CACNB1 CACNB2 CACNB3 TRPM3 SACS KCNK2 KDR TRPM1 USH2A	1.93e-06	199	128	9	CID000023982
Disease	Malignant Neoplasms	TNFRSF10A BIRC6 DNAJC10 MTOR KDR ARHGAP45	1.66e-05	128	123	6	C0006826
Disease	Charlevoix-Saguenay spastic ataxia (implicated_via_orthology)	ANKFY1 SACS	1.72e-05	2	123	2	DOID:0050946 (implicated_via_orthology)
Disease	Bladder Neoplasm	ANKFY1 ANPEP POLB FANCA MTOR CHD6	2.76e-05	140	123	6	C0005695
Disease	Malignant neoplasm of urinary bladder	ANKFY1 ANPEP POLB FANCA MTOR CHD6	2.87e-05	141	123	6	C0005684
Disease	breast angiosarcoma (is_implicated_in)	PTPRB KDR	5.16e-05	3	123	2	DOID:4511 (is_implicated_in)
Disease	Unipolar Depression	ANPEP DDC ADRA1A MTOR KCNK2 KDR KPNA3	1.11e-04	259	123	7	C0041696
Disease	brain glioma (is_marker_for)	PTPRB KDR	1.71e-04	5	123	2	DOID:0060108 (is_marker_for)
Disease	Benign Neoplasm	TNFRSF10A BIRC6 DNAJC10 ARHGAP45	1.91e-04	68	123	4	C0086692
Disease	Neoplasms	TNFRSF10A BIRC6 DNAJC10 ARHGAP45	1.91e-04	68	123	4	C0027651
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD6	3.57e-04	7	123	2	DOID:0050834 (implicated_via_orthology)
Disease	HWESASXX measurement	DPP10 ANPEP	3.57e-04	7	123	2	EFO_0021147
Disease	MASA syndrome (implicated_via_orthology)	TRPM3 TRPM1	3.57e-04	7	123	2	DOID:0060246 (implicated_via_orthology)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	ASB15 MYO3A MTOR KDR ALDH1A1	3.99e-04	148	123	5	C0279702
Disease	Autism Spectrum Disorders	DPP10 CHD8 NEMF USH2A	4.49e-04	85	123	4	C1510586
Disease	autism spectrum disorder (implicated_via_orthology)	CHD8 CNTNAP5 CHD6 WDFY3 NAA16	4.50e-04	152	123	5	DOID:0060041 (implicated_via_orthology)
Disease	primary ovarian insufficiency (is_implicated_in)	FANCA DIAPH2	4.75e-04	8	123	2	DOID:5426 (is_implicated_in)
Disease	Major Depressive Disorder	ANPEP DDC ADRA1A MTOR KDR KPNA3	5.59e-04	243	123	6	C1269683
Disease	hearing impairment	GRHL2 FANCA MYO3A USH2A	7.68e-04	98	123	4	C1384666
Disease	bronchopulmonary dysplasia	PAMR1 GRHL2 HIVEP3	8.83e-04	45	123	3	MONDO_0019091
Disease	thyroid gland carcinoma (is_marker_for)	PTPRB KDR	1.11e-03	12	123	2	DOID:3963 (is_marker_for)
Disease	Malformations of Cortical Development	MTOR DYNC1H1	1.52e-03	14	123	2	C1955869
Disease	Cortical Dysplasia	MTOR DYNC1H1	1.52e-03	14	123	2	C0431380
Disease	hippocampal atrophy	RPN2 TTC27 CHD6	1.67e-03	56	123	3	EFO_0005039
Disease	hypertension (is_implicated_in)	CACNB2 PRLHR ADRA1A KDR	1.68e-03	121	123	4	DOID:10763 (is_implicated_in)
Disease	insulin resistance	ANK2 COBLL1 MTOR	1.94e-03	59	123	3	EFO_0002614
Disease	body mass index, type 2 diabetes mellitus	COBLL1 MTOR	1.99e-03	16	123	2	EFO_0004340, MONDO_0005148
Disease	esophageal carcinoma, gastric carcinoma	ATG2B TRPM1	2.25e-03	17	123	2	EFO_0000178, EFO_0002916
Disease	Hemangiosarcoma	PTPRB KDR	2.52e-03	18	123	2	C0018923
Disease	lung non-small cell carcinoma (is_implicated_in)	SFTPB FAT1 PTPRB KDR	2.78e-03	139	123	4	DOID:3908 (is_implicated_in)
Disease	congenital heart disease (implicated_via_orthology)	CHD8 CHD6 NAA16	3.03e-03	69	123	3	DOID:1682 (implicated_via_orthology)
Disease	cytokine measurement	DPP10 ANK2 CPM NMU FANCA BMP10 KPNA3	3.26e-03	461	123	7	EFO_0004873
Disease	esophagus adenocarcinoma (is_implicated_in)	TNFRSF10A KDR	3.44e-03	21	123	2	DOID:4914 (is_implicated_in)
Disease	nucleus accumbens volume	BIRC6 USH2A	3.77e-03	22	123	2	EFO_0006931
Disease	intellectual disability (implicated_via_orthology)	ANK2 UBR4 NAA16	3.84e-03	75	123	3	DOID:1059 (implicated_via_orthology)
Disease	urinary bladder cancer (is_implicated_in)	TNFRSF10A FANCA KDR	3.98e-03	76	123	3	DOID:11054 (is_implicated_in)
Disease	sex interaction measurement, body mass index, age at assessment	COBLL1 DDC	4.12e-03	23	123	2	EFO_0004340, EFO_0008007, EFO_0008343

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLEVPLKQTSQVIGH	C2orf16	416	Q68DN1
LKPSNHATIQSIVRA	BMP3	411	P12645
VFHSNTLERKTPIQI	AMOT	1056	Q4VCS5
HKVLLTGTPLQNTVE	CHD8	971	Q9HCK8
VTKFLAEHPNVTLTI	APOBEC3D	116	Q96AK3
IQHIKDPQDTITSLI	BIRC6	846	Q9NR09
KVHVNPSQSLLTLEG	CLSTN3	566	Q9BQT9
LNNPSKHIIIERSNT	CACNB1	281	Q02641
ADTINHPAQLAKTSL	CACNB3	271	P54284
NHQVPTIKVHTISLS	ADRA1A	446	P35348
STLIKHNTSLDQPCV	ASB15	161	Q8WXK1
GTHVSNLSDLQVIKI	AARSD1	211	Q9BTE6
EQTPLTALHVASLIK	ALDH1A1	196	P00352
AHKVPVTLALNNTLF	ANPEP	671	P15144
TSLREINTILKAQHP	CDK11B	481	P21127
HINNIKPSIIAVTLA	DIAPH2	806	O60879
TKVIHRLQAASPELT	DDC	161	P20711
KTVVANPLLHLSNLT	DMXL1	2191	Q9Y485
TQKTIVRVSPHASLQ	COBLL1	156	Q53SF7
TIPQALNIITAHSEK	ECD	166	O95905
GHVIKLNIETNATTL	DPP10	101	Q8N608
SNSLHKISVDVQRPT	ERMP1	151	Q7Z2K6
QARLSSVPHKAELQI	ATG2B	661	Q96BY7
SVLNNPSKHAIIERS	CACNB2	331	Q08289
KHFQEVAQLISPLTT	MAMDC2	226	Q7Z304
NIVTKQGVTPLHLAS	ANK2	656	Q01484
VLKSHLVNEVPVLAS	ANK2	1486	Q01484
VQDASKLTPLHLAVQ	ANKFY1	901	Q9P2R3
VAHILQTLSAPTKNL	PAXIP1	356	Q6ZW49
SKSPEHVRNIIALSI	PCDH19	981	Q8TAB3
DINPHSGTIITQKAL	FAT1	1711	Q14517
TILLVIKTDSSLHQP	OR52E2	46	Q8NGJ4
ILLRNTSEPATTKQH	PTPRB	1036	P23467
IIFSSVTIPKVLANH	OR1A2	71	Q9Y585
PLLSHQEVKVQTAAL	KPNA3	291	O00505
LSQASPHDISNVLKL	ARHGAP45	821	Q92619
KSNVVSSVVHPLLQL	NMU	116	P48645
TIDLSHLQPQRSIQK	NEMF	781	O60524
RVSHLLQDNLPKSVS	ALAS1	181	P13196
LQALSAVSTHPSIVK	MMS19	556	Q96T76
LKIDIIPNTQEHTLT	HSP90AB2P	71	Q58FF8
PTQKARIVTLLQQHT	ATP9B	851	O43861
SHQLSKQISDLIRQP	KIAA1109	2916	Q2LD37
KALEQPHEISQRTTI	KCNK2	81	O95069
LVPQKIVSVHLQDST	HLCS	11	P50747
ALPIQQDHSTLSKAL	FSIP2	1951	Q5CZC0
IISEHLAVISIKTQP	FSIP2	6536	Q5CZC0
QHIVTTLVKGELNTS	PCYOX1	341	Q9UHG3
NHSNLPDIVSKVLSQ	NAA16	721	Q6N069
NTKVLQTDPATLLHL	COMMD2	161	Q86X83
SSVQIPSRKQITVHN	EVI2B	151	P34910
PKLAVLITNSNVRHS	GALK1	216	P51570
VVTPLHINLSGQKDS	DLG5	716	Q8TDM6
HIAKTLAQLNPESSL	GPI	191	P06744
KTITLHILDVNDNVP	PCDHGB3	436	Q9Y5G1
LENSIIPVHKQTENL	EXOC7	56	Q9UPT5
AIQVLPKLSSSIIHE	KCNAB2	336	Q13303
HNKLLPNVTTVERNI	GGTLC3	161	B5MD39
ATPLNKQVVIAHSLT	HMCN1	1646	Q96RW7
TRKHSNLITVPIQDD	CBLL1	286	Q75N03
QAKSIQVLPSHELVS	PIKFYVE	1121	Q9Y2I7
VLKTVPVNLSLNQDH	GRHL2	116	Q6ISB3
IDTSAQNKHNPLLIV	BMP10	241	O95393
ASDKRSLLPHQISQI	CCDC138	166	Q96M89
SEHAAIPLKASVLSQ	DOCK2	1736	Q92608
KDPEITNLINSTRIH	CPM	106	P14384
HKVLLTGTPLQNSVE	CHD6	621	Q8TD26
QETLTQVTQRPSSHK	FRMPD4	266	Q14CM0
QILTHSPVLKASDAV	FANCA	326	O15360
IHPTTGQKLSLQDAV	DSP	2661	P15924
ALAVTEAQSHLLSKP	CCDC191	596	Q8NCU4
LVPQHLKVFTDSIVT	DNAH7	191	Q8WXX0
QLNKRLPSTHQISVE	DTNB	91	O60941
IALLKHNQEQPTTLS	ENO4	261	A6NNW6
IPQTLSHLKRTVENI	DYNC1H1	4391	Q14204
FPNKISTEHQSLVLV	HORMAD1	16	Q86X24
TLHVPSNTQKITNRD	CCDC168	5586	Q8NDH2
LTPTTFNELVTQRKH	DNAJC10	561	Q8IXB1
KALLNVIHTPDAVTS	BBS1	361	Q8NFJ9
TTSHNPLANILSKVE	RPRD2	501	Q5VT52
LSVLQNTPIHVVKDT	SACS	2941	Q9NZJ4
TSESTKQPKLLHQVV	POLB	201	P06746
LSFKDHLPVTQIVIT	CNTNAP5	751	Q8WYK1
KQHIIPLENVTIDSI	PLEKHF2	76	Q9H8W4
KTIQSLQISAIILHP	PAMR1	536	Q6UXH9
VPTQVELLIKQATSH	MTOR	2521	P42345
QIQEHQPKVALSTLR	RPP40	201	O75818
NSEIPVVNLKTSTHQ	RTN3	371	O95197
SQDPSTKVHIKVLQT	TAS2R45	216	P59539
VTSAVLSQKVTHLIP	USH2A	2771	O75445
IKLSTPAVINAHVST	PRSS3P2	111	Q8NHM4
AVTPFQSLQLVHQLK	PRLHR	46	P49683
KQFVEQHTPQLLTLV	SFTPB	336	P07988
ALPVSNTHVKTSNLA	SPATA31A6	756	Q5VVP1
QPTQHLDISALAKVS	IQCA1L	716	A6NCM1
IIKSLHQNPVTLFTV	PKDREJ	1176	Q9NTG1
LPVSNTHVKTSNLAA	SPATA31A7	761	Q8IWB4
AGHLEQPQISSTKTL	TRGV9	21	Q99603
LLPKTISQHQISTSI	MT-ND5	561	P03915
KIVINTVPQLHSEKT	SEMA4D	711	Q92854
PIATERTVAHLNTLK	PGBD1	301	Q96JS3
RVPEQQTQASLKSHL	NINL	126	Q9Y2I6
KLAIISPTSQILHTD	SRBD1	551	Q8N5C6
SAAHIQTSPQAKVLL	SH3RF1	561	Q7Z6J0
LKPVNSEETVLQALH	C10orf82	66	Q8WW14
TNLKTHVAVPETALL	ATP11B	181	Q9Y2G3
VLTILLAHKQSSQPA	ZC3HC1	461	Q86WB0
LPVSNTHVKTSNLAA	SPATA31A3	761	Q5VYP0
SLSQSVHVKPENLRL	USP19	716	O94966
LSTNLVASIQRPDKH	ZNF182	146	P17025
SSTEIHSVLQKLGVQ	ZC3H12A	61	Q5D1E8
AHKTVPQQVALLDSL	WDFY3	2106	Q8IZQ1
QSTLGLIKPHATSEQ	NME8	451	Q8N427
LPVSNTHVKTSNLAA	SPATA31A1	761	Q5TZJ5
LPVSNTHVKTSNLAA	SPATA31A5	761	Q5VU36
LRNVKNEVSSSPQHL	TNN	331	Q9UQP3
LSQPLTQATVKLEHA	RPN2	296	P04844
HVGLTPSISVLQNEK	TRPM3	96	Q9HCF6
LQQSHPLSATQIQVK	SPTAN1	321	Q13813
RNEFTITHVLIPKQS	STAMBP	291	O95630
KVLQFPSLHTTTNVS	HIVEP3	1591	Q5T1R4
QDQTLVQIFKPLTHS	PHF3	581	Q92576
KALPTLSHIQEAQSA	YJU2B	161	P13994
LQVVPSSAATIKLHD	TNFRSF10A	101	O00220
KHSSLITPLQAVAQR	PRKDC	2786	P78527
TISPSLNKTDVIHGQ	TRPM1	1376	Q7Z4N2
SPLNVLRKVSHNTVS	TOPAZ1	376	Q8N9V7
PAIAKSQEQVHLLRS	ZHX2	631	Q9Y6X8
PQIISSTIKTHVSNK	ZNF415	226	Q09FC8
TNPISKEKQSHVVSL	KDR	401	P35968
KNNPVHTLTEVELLA	TTC27	356	Q6P3X3
TQVLIGTDSIPNLHK	UBR4	4736	Q5T4S7
QTASHNRIPKEITVS	YEATS2	1381	Q9ULM3
IPKLFLSQVTTISHI	PRO1933	21	Q9H354
KQTLSIQQESPLRTH	ZNF776	66	Q68DI1
PLLSHQEVKVQTAAL	KPNA4	291	O00629
LIAPAITNSKERHNS	KCNJ3	371	P48549
TVSIQVKNPQLLHVS	BPIFA4P	81	Q86YQ2
TSKINAILAHNSPVL	LRRIQ3	206	A6PVS8
PTVSELLQHKFITQI	MYO3A	276	Q8NEV4