Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA3 GRIA4

1.09e-044862GO:0004971
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D16 DOCK5 EVI5 TRIO KALRN PLCB1 MCF2 ARHGAP17 HERC1

3.32e-04507869GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D16 DOCK5 EVI5 TRIO KALRN PLCB1 MCF2 ARHGAP17 HERC1

3.32e-04507869GO:0030695
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

KALRN PLCB1 GRIA3 GRIA4

2.30e-0540864GO:1990806
Domain-

PLCB1 GPCPD1 PLCH1

2.16e-04258833.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCB1 GPCPD1 PLCH1

2.16e-0425883IPR017946
DomainCRAL_TRIO

TRIO KALRN MCF2

2.72e-0427883PS50191
DomainCRAL-TRIO_dom

TRIO KALRN MCF2

3.04e-0428883IPR001251
DomainSpectrin_repeat

TRIO KALRN MCF2

3.38e-0429883IPR002017
DomainTLV_coat

ERVV-2 ERVV-1

4.54e-047882PF00429
DomainSpectrin/alpha-actinin

TRIO KALRN MCF2

4.54e-0432883IPR018159
DomainSPEC

TRIO KALRN MCF2

4.54e-0432883SM00150
DomainTLV/ENV_coat_polyprotein

ERVV-2 ERVV-1

6.03e-048882IPR018154
DomainResIII

IFIH1 RTEL1

6.03e-048882PF04851
DomainHelicase/UvrB_N

IFIH1 RTEL1

6.03e-048882IPR006935
DomainPH

AFAP1 TRIO KALRN MCF2 PLCH1 PHLDB2

2.01e-03278886SM00233
DomainPH_DOMAIN

AFAP1 TRIO KALRN MCF2 PLCH1 PHLDB2

2.05e-03279886PS50003
DomainPH_domain

AFAP1 TRIO KALRN MCF2 PLCH1 PHLDB2

2.09e-03280886IPR001849
DomainPLipase_C_Pinositol-sp_Y

PLCB1 PLCH1

2.21e-0315882IPR001711
DomainEF-hand_like

PLCB1 PLCH1

2.21e-0315882PF09279
DomainPIPLC_Y_DOMAIN

PLCB1 PLCH1

2.21e-0315882PS50008
DomainPI-PLC_fam

PLCB1 PLCH1

2.21e-0315882IPR001192
DomainPLC_EF-hand-like

PLCB1 PLCH1

2.21e-0315882IPR015359
DomainPI-PLC-Y

PLCB1 PLCH1

2.21e-0315882PF00387
DomainPLCYc

PLCB1 PLCH1

2.21e-0315882SM00149
DomainIontro_rcpt

GRIA3 GRIA4

3.20e-0318882IPR001320
DomainLig_chan-Glu_bd

GRIA3 GRIA4

3.20e-0318882PF10613
DomainIono_rcpt_met

GRIA3 GRIA4

3.20e-0318882IPR001508
DomainGlu/Gly-bd

GRIA3 GRIA4

3.20e-0318882IPR019594
DomainLig_chan-Glu_bd

GRIA3 GRIA4

3.20e-0318882SM00918
DomainLig_chan

GRIA3 GRIA4

3.20e-0318882PF00060
DomainPI-PLC-X

PLCB1 PLCH1

3.20e-0318882PF00388
DomainPBPe

GRIA3 GRIA4

3.20e-0318882SM00079
DomainPLCXc

PLCB1 PLCH1

3.20e-0318882SM00148
DomainDH_1

TRIO KALRN MCF2

3.27e-0363883PS00741
DomainPIPLC_X_DOMAIN

PLCB1 PLCH1

3.56e-0319882PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB1 PLCH1

3.56e-0319882IPR000909
DomainPH_dom-like

AFAP1 TRIO KALRN PLCB1 MCF2 PLCH1 PHLDB2

3.97e-03426887IPR011993
DomainRhoGEF

TRIO KALRN MCF2

4.06e-0368883SM00325
DomainCRAL_TRIO

TRIO KALRN

4.35e-0321882PF00650
DomainRhoGEF

TRIO KALRN MCF2

4.41e-0370883PF00621
DomainDH_2

TRIO KALRN MCF2

4.41e-0370883PS50010
DomainPH

AFAP1 TRIO KALRN MCF2 PHLDB2

4.56e-03229885PF00169
DomainDH-domain

TRIO KALRN MCF2

4.59e-0371883IPR000219
Domain-

TRIO KALRN MCF2

4.59e-03718831.20.900.10
Domain-

TRIO KALRN

5.21e-03238823.40.525.10
DomainSpectrin

TRIO KALRN

5.21e-0323882PF00435
DomainSEC14

TRIO KALRN

6.14e-0325882SM00516
PathwayPID_RAC1_REG_PATHWAY

TRIO KALRN MCF2 ARHGAP17

3.62e-0538704M241
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

AKAP9 SDCCAG8 CNTRL TUBGCP3 DYNC1H1

4.99e-0581705M748
PathwayREACTOME_MITOTIC_PROMETAPHASE

AKAP9 CENPF SDCCAG8 CNTRL TUBGCP3 DYNC1H1 KNL1

6.64e-05204707M4217
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

AKAP9 SDCCAG8 CNTRL TUBGCP3 DYNC1H1

1.07e-0495705M6729
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

PLCB1 GRIA3 GRIA4

1.69e-0422703M39795
PathwayREACTOME_RHOG_GTPASE_CYCLE

DOCK5 TRIO KALRN MCF2

4.22e-0471704MM15604
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

AKAP9 SDCCAG8 CNTRL DYNC1H1

4.45e-0472704M27749
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

AKAP9 CENPF SDCCAG8 CNTRL TUBGCP3 DYNC1H1

4.66e-04200706M864
PathwayREACTOME_CILIUM_ASSEMBLY

AKAP9 SDCCAG8 CNTRL TTC21B DYNC1H1 EXOC4

4.79e-04201706M27472
PathwayREACTOME_RHOG_GTPASE_CYCLE

DOCK5 TRIO KALRN MCF2

4.94e-0474704M41814
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

AKAP9 UACA TRIO CENPF DYNC1H1 EXOC4 KPNB1

2.88e-0812090731413325
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 DROSHA ZGRF1 ZNF644 UNK ARHGAP17 ZDBF2 PIAS1 FAM135A KNL1 EXOC4

3.66e-07588901138580884
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

AKAP9 TRIO KALRN CENPF DYNC1H1 EXOC4

2.79e-0615190617043677
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

BOC KARS1 AKAP9 UACA TRIO KALRN DROSHA TUBGCP3 KPNB1

5.86e-0649790923414517
Pubmed

Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.

GRIA3 GRIA4

6.62e-06290212670305
Pubmed

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.

GRIA3 GRIA4

6.62e-0629027992055
Pubmed

Elimination of redundant synaptic inputs in the absence of synaptic strengthening.

GRIA3 GRIA4

6.62e-06290222090494
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-2 ERVV-1

6.62e-06290218826608
Pubmed

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.

GRIA3 GRIA4

6.62e-06290218316356
Pubmed

The Shh receptor Boc is important for myelin formation and repair.

BOC CX3CR1

6.62e-06290231048318
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

6.62e-06290226858404
Pubmed

Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.

ERVV-2 ERVV-1

6.62e-06290223555306
Pubmed

GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.

GRIA3 GRIA4

6.62e-06290221690196
Pubmed

The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells.

GRIA3 GRIA4

1.98e-05390228397107
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

1.98e-05390231801062
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA3 GRIA4

1.98e-05390218163426
Pubmed

Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.

GRIA3 GRIA4

1.98e-05390212172541
Pubmed

Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase.

RTEL1 KPNB1

1.98e-05390238132118
Pubmed

Synaptic AMPA receptor plasticity and behavior.

GRIA3 GRIA4

1.98e-05390219217372
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

AKAP9 CNTRL TUBGCP3 DYNC1H1

2.67e-056690412221128
Pubmed

Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.

KARS1 SDCCAG8 IRAK4 PLCB1 CXCL11

3.40e-0514190520056178
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

AKAP9 UACA TRIO KALRN CENPF PLCB1 GRIA3 GRIA4 DYNC1H1 PHLDB2 KPNB1

3.93e-05963901128671696
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA3 GRIA4

3.96e-05490210688364
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA3 GRIA4

3.96e-05490228608780
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA3 GRIA4

3.96e-0549029221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA3 GRIA4

3.96e-05490225337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA3 GRIA4

3.96e-05490217828255
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA3 GRIA4

3.96e-05490224652293
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA3 GRIA4

3.96e-05490217409242
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA3 GRIA4

3.96e-05490214561864
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA3 GRIA4

3.96e-05490210027300
Pubmed

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size.

DYNC1H1 KPNB1

3.96e-05490227477284
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA3 GRIA4

3.96e-0549021319477
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA3 GRIA4

3.96e-05490212692557
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA3 GRIA4

3.96e-05490212125045
Pubmed

Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia.

GRIA3 GRIA4

3.96e-05490225433904
Pubmed

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.

TRIO MCF2

3.96e-05490217606614
Pubmed

Molecular cloning and characterization of a novel phospholipase C, PLC-eta.

PLCB1 PLCH1

3.96e-05490215702972
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA3 GRIA4

3.96e-0549029648857
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

AKAP9 SDCCAG8 CNTRL TUBGCP3 DYNC1H1

4.01e-0514690521399614
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UACA RTEL1 ATRNL1 TTC21B TXNDC16 PLCH1 FAM135A EXOC4

4.32e-0549390815368895
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TRIO KALRN PLCB1 GRIA3 GRIA4 DYNC1H1

4.99e-0525190627507650
Pubmed

NMDA Receptors Regulate the Development of Neuronal Intrinsic Excitability through Cell-Autonomous Mechanisms.

GRIA3 GRIA4

6.59e-05590229163060
Pubmed

Innate immune interleukin-1 receptor-associated kinase 4 exacerbates viral myocarditis by reducing CCR5(+) CD11b(+) monocyte migration and impairing interferon production.

IFIH1 IRAK4

6.59e-05590224030499
Pubmed

Assembly of high order G alpha q-effector complexes with RGS proteins.

TRIO KALRN

6.59e-05590218936096
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA3 GRIA4

6.59e-0559021717158
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA3 GRIA4

6.59e-05590216129400
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA3 GRIA4

6.59e-0559029482932
Pubmed

The TRPM7 channel is inactivated by PIP(2) hydrolysis.

TRPM7 PLCB1

6.59e-05590211941371
Pubmed

Antimicrobial immunity impedes CNS vascular repair following brain injury.

IFIH1 CX3CR1

6.59e-05590234556874
Pubmed

Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.

GRIA3 GRIA4

6.59e-05590215797551
Pubmed

Association of the proto-oncogene product dbl with G protein betagamma subunits.

KALRN MCF2

6.59e-05590210518015
Pubmed

Anti-CD200R2, anti-IL-9, anti-IL-35, or anti-TGF-β abolishes increased graft survival and Treg induction induced in cromolyn-treated CD200R1KO.CD200tg mice.

CD200R1 IL9

9.87e-05690224142033
Pubmed

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.

ERVV-2 ERVV-1

9.87e-05690223085571
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 CENPF ZGRF1 ZNF644 ZDBF2 KNL1 EXOC4

1.09e-0441890734709266
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

UACA TRIO PLCB1 PLCH1 FAM135A PHLDB2 EXOC4

1.14e-0442190736976175
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK5 AFMID UACA TRIO CACNA2D2 RTEL1 POLR2J3 ABCC8 TM9SF4 SDCCAG8 TTC21B ZNF248 EXOC4

1.18e-041489901328611215
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA3 GRIA4

1.38e-04790221368048
Pubmed

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons.

CX3CR1 KPNB1

1.38e-04790229434374
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA3 GRIA4

1.38e-04790233981040
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA3 GRIA4

1.38e-04790210407040
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA3 GRIA4

1.38e-0479029016303
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA3 GRIA4

1.38e-0479029651535
Pubmed

Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity.

IFIH1 CX3CR1

1.38e-04790238427731
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA3 GRIA4

1.38e-04790227076426
Pubmed

The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.

DYNC1H1 KPNB1

1.38e-04790226195665
Pubmed

Functional proteomics mapping of a human signaling pathway.

DROSHA ERVV-1 HERC1 PIAS1 DYNC1H1 ZNF518A KNL1 KPNB1

1.51e-0459190815231748
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 CACNA2D2 ATRNL1 PLCB1

1.64e-041059049628581
Pubmed

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.

GRIA3 GRIA4

1.84e-04890221172611
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA3 GRIA4

1.84e-04890223217150
Pubmed

Syncytins expressed in human placental trophoblast.

ERVV-2 ERVV-1

1.84e-04890233504453
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPM7 NTRK3 PKDREJ

2.06e-044490319322198
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

KARS1 CACNA2D2 SDCCAG8 TTC21B DDX43 KNL1

2.26e-0433190619490893
Pubmed

Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.

NTRK3 IL9

2.36e-0499028530078
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA3 GRIA4

2.36e-04990224292102
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA3 GRIA4

2.36e-0499029051806
Pubmed

trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues.

NTRK3 IL9

3.59e-04119028223273
Pubmed

Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.

KARS1 KALRN

3.59e-041190217607528
Pubmed

Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.

NTRK3 CX3CR1

3.59e-041190230252950
Pubmed

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.

AKAP9 CNTRL DYNC1H1

4.21e-045690311076968
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIA3 GRIA4

4.30e-041290211891216
Pubmed

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.

AKAP9 CNTRL DYNC1H1

4.43e-045790316462731
Pubmed

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

AKAP9 CNTRL DYNC1H1

4.66e-045890312852856
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 GATD3 TRIO KALRN TRPM7 DROSHA ATRNL1 PIAS1 DYNC1H1 EXOC4 KPNB1

4.83e-041285901135914814
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

KARS1 CCDC186 TUBGCP3 TTC21B PHLDB2

5.02e-0425190529778605
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA3 GRIA4

5.07e-041390220859245
Pubmed

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.

GRIA3 GRIA4

5.07e-041390225218043
Pubmed

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.

TRPM7 GRIA3 CX3CR1

5.15e-046090332027825
Pubmed

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

AKAP9 CNTRL DYNC1H1

5.41e-04619037790358
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

USP34 AKAP9 UACA TRIO JADE3 CCDC186 IRAK4 DDX43 KNL1

5.88e-0491090936736316
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

TEKT3 TDRD6

5.91e-041490217662146
Pubmed

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.

NTRK3 IL9

5.91e-04149028114702
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DOCK5 CCN4 KARS1 RDH16 CCDC73 CENPF DROSHA DYNC1H1

6.53e-0473690829676528
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIA3 GRIA4

6.80e-04159029481670
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

UNK HERC1 DYNC1H1 COMMD6 KPNB1

7.09e-0427190525737280
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

AKAP9 UACA CENPF CNTRL TUBGCP3 UNK PHLDB2 COMMD6

7.64e-0475490833060197
Pubmed

Characterization of human colon cancer antigens recognized by autologous antibodies.

SDCCAG8 TDRD6

7.76e-04169029610721
Pubmed

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.

GRIA3 GRIA4

7.76e-041690216055064
Pubmed

Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells.

BOC NTRK3

7.76e-041690230661738
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

TRIO KALRN NTRK3 GRIA3 DYNC1H1

8.34e-0428190528706196
Cytoband3q13.2

BOC PHLDB2 CD200R1

3.15e-05319033q13.2
Cytoband6q12-q13

COL19A1 DDX43

3.79e-0559026q12-q13
CytobandEnsembl 112 genes in cytogenetic band chr6q13

COL19A1 DDX43 FAM135A

3.05e-0466903chr6q13
CytobandEnsembl 112 genes in cytogenetic band chr3q13

BOC TRAT1 PHLDB2 CD200R1

9.66e-04221904chr3q13
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA3 GRIA4

7.14e-0546321200
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO KALRN MCF2

1.58e-0366633722
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB1 PLCH1

1.97e-0319632832
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

BOC TRIO KALRN NTRK3

2.40e-03161634593
CoexpressionGSE14350_TREG_VS_TEFF_UP

ATG10 AKAP9 TRAT1 CCDC186 GPCPD1 TPGS2 PIAS1

5.33e-06199897M3417
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP

BOC IFIH1 ATG10 KALRN ABCC8 TXNDC16 PHLDB2

9.66e-06218897M1099
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP

BOC IFIH1 ATG10 KALRN ABCC8 TXNDC16 PHLDB2

1.57e-05235897MM978
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 TRPM7 POLR2J3 ZNF644 PLCB1 GPCPD1 HERC1 DYNC1H1

4.23e-09188898ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CENPF ABCC8 NTRK3 MCF2 KNL1

1.08e-06167896b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CENPF ABCC8 NTRK3 MCF2 KNL1

1.08e-0616789694fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CENPF ABCC8 NTRK3 MCF2 KNL1

1.08e-06167896eff3723fe60755272eca237459165e436e919ece
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CCN4 AFAP1 UACA KALRN C7 PHLDB2

2.81e-06197896f1c8936986123a3151140c374fcd62d6705c530b
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

EVI5 AKAP9 CENPF CCDC186 ZNF644 CNTRL

2.89e-0619889676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

AKAP9 UACA CCDC186 ZNF644 CNTRL GOLM1

2.97e-0619989661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFIH1 USP34 AKAP9 ZNF644 ZRANB2 DYNC1H1

3.06e-0620089612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEKT3 STAC2 OR8J3 ZNF799 ZNF443

7.66e-06135895b444005987093efab3265201b3541d7941816cc2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2 GRIA4

1.85e-05162895c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2 GRIA4

1.85e-05162895f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2 GRIA4

1.85e-051628955d902bb31e691aea9749617cc88303c2448f24b8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF ZGRF1 TPGS2 ZNF248 KNL1

1.91e-051638953efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

STAC2 KALRN ATRNL1 NTRK3 GRIA4

2.14e-05167895c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

THNSL1 CCDC73 TRAT1 CENPF KNL1

2.27e-05169895c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

2.33e-0517089599dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

2.33e-051708953a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

2.33e-05170895cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CENPF ATRNL1 ZGRF1 KNL1

2.40e-05171895b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CENPF ATRNL1 ZGRF1 KNL1

2.40e-05171895b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 AKAP9 CCDC186 CNTRL C7

2.91e-0517889501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 THNSL1 RTEL1 ZGRF1 TM9SF4

2.91e-0517889550bb1f2c6a8d050ff2af217fd76c3b1b7b4a4a69
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC DOCK5 AFAP1 ATRNL1 GRIA3

3.32e-051838957eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CCN4 KALRN ATRNL1 ZDBF2 C7

3.68e-0518789576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

3.68e-0518789515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

3.68e-05187895f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ABCC8 NTRK3 MCF2

3.77e-0518889532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ATRNL1 NTRK3 C7

3.97e-0519089570c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 UACA KALRN ATRNL1 C7

4.07e-05191895107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 UACA KALRN ATRNL1 C7

4.07e-05191895bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN NTRK3 ARHGAP17 C7

4.07e-051918957b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN NTRK3 ARHGAP17 C7

4.07e-05191895cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 UACA KALRN ATRNL1 C7

4.17e-05192895bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC CCN4 ATRNL1 NTRK3 C7

4.17e-05192895d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 UACA KALRN ATRNL1 C7

4.17e-051928950ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CENPF ATRNL1 ZGRF1 GRIA4 KNL1

4.27e-05193895bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ATRNL1 NTRK3 C7

4.49e-05195895edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC CCN4 ATRNL1 NTRK3 C7

4.49e-051958953c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP9 ABCC8 HERC1 DYNC1H1 PHLDB2

4.49e-051958953e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP9 ABCC8 HERC1 DYNC1H1 PHLDB2

4.49e-051958957796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 AKAP9 ZRANB2 ZDBF2 HERC1

4.71e-0519789557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFAP1 KALRN ABCC8 PLCB1 C7

4.71e-05197895b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ATRNL1 NTRK3 C7

4.71e-051978959b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP9 TRPM7 PLCB1 GOLM1 SLC5A3

4.83e-05198895688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 KALRN ATRNL1 NTRK3 C7

4.83e-0519889579576525a10ed3e3a9d1608077cd16ecda23376f
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 AKAP9 ZNF644 ZRANB2 HERC1

4.94e-05199895f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

TBC1D16 CENPF GRIA4 KNL1

1.34e-04130894169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPF ZGRF1 UNK KNL1

1.51e-041348944d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellASK454-Epithelial-Type_2|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

AFAP1 CENPF JADE3 TUBGCP3

1.60e-04136894ff9a5e111993fdb3ac64c5ef269e3460ff994517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

2.57e-041548943211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

2.57e-04154894c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CACNA2D2 ABCC8 NTRK3

2.57e-04154894b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 CACNA2D2 ABCC8 NTRK3

2.57e-04154894d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

2.57e-041548944c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATRNL1 MCF2 GRIA3 PKDREJ

2.63e-0415589477fdae85d36efb776db977eb424b32487ef222e4
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 TUBGCP3 GPCPD1 CX3CR1

2.77e-041578940ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 TUBGCP3 GPCPD1 CX3CR1

2.77e-04157894fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 GPCPD1 PYGL PKDREJ

2.83e-041588942a222301474c4dfd9a776e197c10f4c1cacceb62
ToppCellfacs-Heart-LV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEKT3 TRAT1 ZDBF2 PKDREJ

2.83e-0415889412a82230c01de552f12977634c304626e1cd6903
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 GPCPD1 PYGL PKDREJ

2.83e-04158894ff9878fd768f22bf2ee4805bac2ba01cb3cb804a
ToppCellfacs-Heart-LV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEKT3 TRAT1 ZDBF2 PKDREJ

2.83e-04158894bd432ecd2524656804e7c2775250e27db7906b70
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STAC2 AFAP1 CACNA2D2 PLCH1

2.90e-04159894c64fff8d89f84d1f5a0cc432e31f56f741162505
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

3.04e-041618941b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

3.26e-0416489443630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 MCF2 PYGL

3.26e-04164894b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

3.26e-04164894108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 ABCC8 NTRK3 MCF2

3.26e-0416489446208f18325976c89f572f6627aea0582142b92d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STAC2 AFAP1 CACNA2D2 PLCH1

3.42e-0416689459d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFMID TRAT1 CENPF KNL1

3.50e-04167894754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFAP1 KALRN ABCC8 C7

3.50e-04167894d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

COL19A1 JADE3 ATRNL1 ZBBX

3.58e-041688948e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

COL19A1 JADE3 ATRNL1 ZBBX

3.58e-041688945535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|368C / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 THNSL1 RTEL1 ZGRF1

3.58e-041688940372c06b70f0ba95bf8cd1363ca7c5f31207f094
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STAC2 AFAP1 CACNA2D2 PLCH1

3.58e-041688942572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

AFAP1 KALRN NEIL2 ABCC8

3.66e-04169894e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAT1 CENPF DDX43 KNL1

3.74e-041708942d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TEKT3 ADPRM CACNA2D2 CX3CR1

3.74e-0417089428fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TEKT3 ADPRM CACNA2D2 CX3CR1

3.74e-04170894239cb4b801b2d71a6facb386f2684c0851504151
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ZGRF1 GRIA4 CXCL11

3.74e-041708947653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF PYGL DDX43 KNL1

3.82e-04171894845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CENPF PLCH1 PHLDB2 ZBBX

3.82e-041718946a489a75eeab2a2d48d604682e93599c20a945fe
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

STAC2 KALRN NTRK3 PLCB1

3.91e-04172894c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 NTRK3 MCF2 PYGL

3.91e-0417289408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCN4 NTRK3 MCF2 PYGL

3.91e-04172894553701349444eb366df3c11f54bb093434f153c6
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 ZGRF1 CXCL11 KNL1

4.00e-0417389420a20429aa898097d5ec4880ed64846558b5890f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GABRP COL19A1 NTRK3 PKDREJ

4.00e-04173894789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAT1 CENPF PHLDB2 KNL1

4.08e-0417489494575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCell343B-Fibroblasts-Fibroblast-H-|343B / Donor, Lineage, Cell class and subclass (all cells)

CCN4 AFAP1 C7 CXCL11

4.08e-041748942627c3983009839fedbc5e3f628739dc026447f4
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAT1 CENPF PHLDB2 KNL1

4.08e-0417489440c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF CX3CR1 CD200R1 KNL1

4.08e-041748947b318796728001c17b4043d2b033330c7be40c78
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC GABRP AFAP1 GOLM1

4.08e-0417489442f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF NTRK3 RNASE10 KNL1

4.08e-0417489441eb0a214a8b4015a26311f77061c8147144f0e7
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAT1 CENPF PHLDB2 KNL1

4.08e-04174894b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCell343B-Fibroblasts-Fibroblast-H|343B / Donor, Lineage, Cell class and subclass (all cells)

CCN4 AFAP1 C7 CXCL11

4.08e-04174894507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAT1 TRPM7 ZDBF2 PHLDB2

4.17e-0417589406eace2e681980456299167b48bd49bcfea5e940
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCN4 CENPF ZGRF1 KNL1

4.17e-041758943e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

AFAP1 KALRN ABCC8 PLCB1

4.26e-04176894043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC CACNA2D2 ABCC8 ZDBF2

4.36e-041778949b02fd91c110b405eba6cb74ceb90b1286535973
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 CCDC186 GRIA3 ZDBF2

4.36e-041778941dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 CCDC186 GRIA3 ZDBF2

4.36e-04177894426a9845df7fd13b02e744532c336c60bc4d4a22
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A

TBC1D16 IFIH1 THNSL1 CNTRL IRAK4 PLCH1 ZNF248

6.81e-061848773945_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

AFAP1 ADPRM TRIO TUBGCP3 PLCB1 KPNB1 SLC5A3

9.30e-061938771022_DN
Drug5255229; Up 200; 13uM; MCF7; HT_HG-U133A_EA

EVI5 USP34 AFAP1 TRIO ATRNL1 CNTRL ZNF248

1.03e-05196877833_UP
Diseasenephronophthisis (implicated_via_orthology)

SDCCAG8 CNTRL TTC21B

1.72e-069823DOID:12712 (implicated_via_orthology)
Diseaseautoimmune thyroid disease

IFIH1 CCN4 TRAT1 CX3CR1

4.29e-04126824EFO_0006812
Diseasecognitive function measurement, self reported educational attainment

CACNA2D2 TTC21B ZNF799 ZNF443 KNL1 EXOC4

4.72e-04355826EFO_0004784, EFO_0008354
Diseasecognitive function measurement

USP34 KALRN CACNA2D2 NTRK3 SDCCAG8 TTC21B PLCB1 GRIA4 ZNF799 ZDBF2 ZNF443 EXOC4

5.87e-0414348212EFO_0008354
DiseaseMalignant neoplasm of breast

BOC GABRP ATG10 AKAP9 COL19A1 KALRN CENPF ZNF644 PLCB1 PKDREJ

7.79e-0410748210C0006142
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

CACNA2D2 NTRK3 TTC21B ZNF799 ZNF443 EXOC4

8.57e-04398826EFO_0003756, EFO_0003888, EFO_0004337
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA3 GRIA4

8.93e-0416822DOID:331 (implicated_via_orthology)
Diseasethyroid peroxidase antibody measurement

KALRN ATRNL1 EXOC4

1.07e-0372823EFO_0005666
Diseaseepilepsy (implicated_via_orthology)

TRIO KALRN CACNA2D2 DYNC1H1

1.12e-03163824DOID:1826 (implicated_via_orthology)
Diseasetaurocholate measurement

DOCK5 ZNF799

1.40e-0320822EFO_0010538
DiseasePrimary microcephaly

TUBGCP3 KNL1

1.70e-0322822C0431350
Diseaseglioma

RTEL1 GRIA4

1.70e-0322822EFO_0005543
Diseasedescending aortic diameter

TBC1D16 AFAP1 ABCC8

1.91e-0388823EFO_0021788
Diseasesciatic neuropathy (biomarker_via_orthology)

KARS1 ABCC8 CX3CR1

2.68e-0399823DOID:11446 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ENYCLMATKQKSNVE

TTC21B

1126

Q7Z4L5
TQCYKQIKDMQEQGQ

AKAP9

2516

Q99996
RKNCQDMIKTYQESE

CCDC186

431

Q7Z3E2
YNKISKIEGIENMCN

CNTRL

156

Q7Z7A1
AKTQVCIPESMYQKV

ANKRD30B

501

Q9BXX2
LMEKVTPDSKQCNNF

CACNA2D2

711

Q9NY47
LLCYKSSKDQQPQME

AFAP1

181

Q8N556
LGVDQSSPKYEQCMK

ADPRM

171

Q3LIE5
AAPQFMFTKQKENEC

CX3CR1

161

P49238
CPAKQMNDYRDKSPQ

ERVV-2

166

B6SEH9
CKTNEFMTPVLKNSQ

ATG10

166

Q9H0Y0
KKCLAVYQPEASMNF

CCN4

271

O95388
KKMSAEELENQYCPS

AFMID

16

Q63HM1
YQKEQCPAGHQVMKE

NEIL2

286

Q969S2
ECYNLSPTKDKMLVA

NTRK3

556

Q16288
DQKNKVVTTPAFMCE

GATD3B

231

A0A0B4J2D5
YSSNPGEKVKICDMQ

HERC1

2176

Q15751
CPAKQMNDYRDKSPQ

ERVV-1

166

B6SEH8
PKTYMRQTSQKEASC

FAM135A

561

Q9P2D6
NEYIEQRKPCDTMKV

GRIA3

741

P42263
NEYIEQRKPCDTMKV

GRIA4

731

P48058
DQYSELLKMTSPCEK

EVI5

186

O60447
MYVTYCKNKPDSNQL

KALRN

1371

O60229
QNKKLEDNYCEITGM

KNL1

121

Q8NG31
EISPYENKMGKTCNS

KNL1

1771

Q8NG31
SLCMDEKQITQNYSK

CD200R1

26

Q8TD46
IDGKNIKMNNTENCY

TUBGCP3

261

Q96CW5
IKMNNTENCYKVEGK

TUBGCP3

266

Q96CW5
DVNVALKKFMENPCY

OR8J3

296

Q8NGG0
NFLINKMQEDPASKC

IL9

31

P15248
VKTKCFEMTIPQFQN

COMMD6

56

Q7Z4G1
QVPQKLEQCMASKHY

EXOC4

136

Q96A65
ADICTMVRQKQNKYP

GPCPD1

506

Q9NPB8
QPETSYDIKMQCFNE

BOC

781

Q9BWV1
EDIKSSPKQYMQCFT

DOCK5

1416

Q9H7D0
NQCNFKPQMDLEVKE

CENPF

1186

P49454
MSSYLPAKQELKDQC

COL19A1

271

Q14993
CQYKMGEENINLTIK

CCDC73

231

Q6ZRK6
EKLQNSRCVCKMPYE

C7

706

P10643
KAIHCVQNMKPEEYA

IFIH1

856

Q9BYX4
MVLDTNLCPKEKNYE

ATRNL1

991

Q5VV63
SLMEIVKNSAKDCYP

KPNB1

531

Q14974
QMYAKYCQNKPRSET

MCF2

586

P10911
DQKNKVVTTPAFMCE

GATD3

231

P0DPI2
DKFKVQYPQSQACKM

DYNC1H1

621

Q14204
EAITVQQKQMPFCDK

IRAK4

116

Q9NWZ3
KFSYDLSQCINQMKE

GOLM1

151

Q8NBJ4
AFQCYPEVMENIKKA

DDX43

246

Q9NXZ2
EKASIMYPSNNCDKI

CXCL11

46

O14625
NTEDLQCYVKPTKNM

JADE3

726

Q92613
KYPMDTQTCKLQLES

GABRP

166

O00591
NKDTKVPNACLFTMN

POLR2J3

21

Q9H1A7
QPYKCQQEYMTKVLE

RTEL1

16

Q9NZ71
QKYAEECKGMIVTNP

DROSHA

731

Q9NRR4
EEKNENMKLPCTEYL

TDRD6

1181

O60522
MKKEICNAYTELNDP

KARS1

491

Q15046
YKKSAEQMEQKCTQD

RDH16

246

O75452
KVEQCKDQLAADMYN

ARHGAP17

186

Q68EM7
TKVCGEMRYQLNKTN

SDCCAG8

451

Q86SQ7
SSEKMCLPAEKFVQN

PKDREJ

1801

Q9NTG1
ENCSPKEEPYQMQEK

SLC5A3

556

P53794
KEEPYQMQEKSILRC

SLC5A3

561

P53794
VKANSLYIDQEKCMS

TEKT3

461

Q9BXF9
CFDATLYIQMNEKKP

PIAS1

356

O75925
YSEQKTQLDNCPESM

PHLDB2

686

Q86SQ0
SPFNKQRYKMVIEAC

ABCC8

791

Q09428
CTKQNVTEFPIIKMY

TXNDC16

456

Q9P2K2
VNTPFQVLMNSEKKC

TM9SF4

86

Q92544
KMKEPSQSCIAQYAF

RNASE10

126

Q5GAN6
KEQGYMSLKENQICV

STAC2

366

Q6ZMT1
KDQQVAPDKTCMQFS

TBC1D16

361

Q8TBP0
PSMTNQCKETFKIIN

ZDBF2

1591

Q9HCK1
LGPCQKNLYKDVMQE

ZNF799

21

Q96GE5
RTKQQEKMEYQVCAA

THNSL1

711

Q8IYQ7
ENCYEQMKARPEKSV

TRAT1

76

Q6PIZ9
MPSEQKQLFCDEKQT

ZNF518A

1

Q6AHZ1
DSPKQQAKMAEYCRL

PLCB1

416

Q9NQ66
KVEQKMNNVTTDYCL

PLCH1

241

Q4KWH8
NMCNTPKYAKLEERT

ZRANB2

86

O95218
KNNCVMPEDVKNFYL

TPGS2

56

Q68CL5
KSMQRCYEKEQQTVT

UACA

1136

Q9BZF9
QTGEKMYECNPVEKS

ZNF677

206

Q86XU0
SNCVPNKSKMQEVDF

ZNF644

311

Q9H582
TKPKYLIQQEECAEM

ZGRF1

291

Q86YA3
LGPCQKNLYKDVMQE

ZNF443

21

Q9Y2A4
CKTYTMDKQPLNTGE

USP34

1961

Q70CQ2
PEIYKSTKCNDMQQS

UNK

291

Q9C0B0
YVKCQDKVSQLYMNP

PYGL

781

P06737
IDKNVQYPECLDMKL

USP17L15

291

C9J2P7
NILMKDDKDPQCNIF

TRPM7

1316

Q96QT4
PYKICDSCEMNLKNI

ZNF248

136

Q8NDW4
KPTVNYKMANSSECE

ZBBX

111

A8MT70
YKMANSSECEKPKIN

ZBBX

116

A8MT70
QMYVTYCKNKPDSTQ

TRIO

1381

O75962
QMQLYTAETNKKDCQ

ZNF114

266

Q8NC26