Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of nuclear pore	NUP98 NUP54	3.75e-04	25	23	2	GO:0017056
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	CNOT3 TNRC6C CNOT7	6.47e-06	33	23	3	GO:0000289
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CNOT3 TNRC6C CNOT7	5.06e-05	65	23	3	GO:0000288
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6C CNOT7	1.07e-04	14	23	2	GO:0060213
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	TNRC6C CNOT7	1.41e-04	16	23	2	GO:1900153
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6C CNOT7	1.41e-04	16	23	2	GO:0060211
GeneOntologyBiologicalProcess	positive regulation of mRNA metabolic process	NUP98 CNOT3 TNRC6C CNOT7	1.78e-04	259	23	4	GO:1903313
GeneOntologyBiologicalProcess	nuclear pore organization	NUP98 NUP54	1.80e-04	18	23	2	GO:0006999
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD2 NUP54	2.23e-04	20	23	2	GO:0006607
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	TNRC6C CNOT7	4.10e-04	27	23	2	GO:1900151
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process	CNOT3 TNRC6C CNOT7	4.13e-04	132	23	3	GO:0000956
GeneOntologyBiologicalProcess	mRNA transport	NUP98 RGPD2 NUP54	5.44e-04	145	23	3	GO:0051028
GeneOntologyBiologicalProcess	RNA transport	NUP98 RGPD2 NUP54	9.38e-04	175	23	3	GO:0050658
GeneOntologyBiologicalProcess	nucleic acid transport	NUP98 RGPD2 NUP54	9.38e-04	175	23	3	GO:0050657
GeneOntologyBiologicalProcess	establishment of RNA localization	NUP98 RGPD2 NUP54	9.86e-04	178	23	3	GO:0051236
GeneOntologyCellularComponent	CCR4-NOT core complex	CNOT3 CNOT7	1.73e-05	6	23	2	GO:0030015
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	NUP98 RGPD2	5.18e-05	10	23	2	GO:0044614
GeneOntologyCellularComponent	CCR4-NOT complex	CNOT3 CNOT7	1.38e-04	16	23	2	GO:0030014
GeneOntologyCellularComponent	nuclear pore nuclear basket	NUP98 RGPD2	1.75e-04	18	23	2	GO:0044615
GeneOntologyCellularComponent	nuclear pore	NUP98 RGPD2 NUP54	1.81e-04	101	23	3	GO:0005643
GeneOntologyCellularComponent	P-body	CNOT3 TNRC6C CNOT7	1.86e-04	102	23	3	GO:0000932
GeneOntologyCellularComponent	nuclear inclusion body	NUP98 RGPD2	2.17e-04	20	23	2	GO:0042405
GeneOntologyCellularComponent	vesicle coat	SEC24A TBC1D5	2.45e-03	67	23	2	GO:0030120
GeneOntologyCellularComponent	cornified envelope	FLG2 DSC1	2.60e-03	69	23	2	GO:0001533
GeneOntologyCellularComponent	cytoplasmic ribonucleoprotein granule	CNOT3 TNRC6C CNOT7	3.08e-03	269	23	3	GO:0036464
HumanPheno	Aggressive behavior	ECM1 FTSJ1 SH2B1 CDK19 CAMTA1 SCN8A	6.75e-05	516	9	6	HP:0000718
HumanPheno	Abnormal aggressive, impulsive or violent behavior	ECM1 FTSJ1 SH2B1 CDK19 CAMTA1 SCN8A	6.75e-05	516	9	6	HP:0006919
HumanPheno	Abnormal thought pattern	ECM1 SH2B1 CDK19 CAMTA1 SCN8A	2.95e-04	404	9	5	HP:5200269
HumanPheno	Autistic behavior	FTSJ1 CNOT3 SH2B1 CDK19 CAMTA1 SCN8A	3.20e-04	678	9	6	HP:0000729
HumanPheno	Paroxysmal dyskinesia	SH2B1 SCN8A	3.29e-04	16	9	2	HP:0007166
Domain	IQ	CAMTA1 SCN8A	3.42e-03	71	23	2	PF00612
Domain	IQ	CAMTA1 SCN8A	4.43e-03	81	23	2	SM00015
Domain	IQ_motif_EF-hand-BS	CAMTA1 SCN8A	5.44e-03	90	23	2	IPR000048
Domain	IQ	CAMTA1 SCN8A	5.80e-03	93	23	2	PS50096
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	NUP98 RGPD2 NUP54	2.33e-05	40	20	3	MM14945
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	NUP98 RGPD2 NUP54	2.52e-05	41	20	3	MM15200
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	NUP98 RGPD2 NUP54	2.71e-05	42	20	3	MM15039
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	NUP98 RGPD2 NUP54	2.91e-05	43	20	3	MM14609
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	NUP98 RGPD2 NUP54	3.81e-05	47	20	3	MM14939
Pathway	REACTOME_GENE_SILENCING_BY_RNA	NUP98 RGPD2 NUP54	4.32e-05	49	20	3	MM14837
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	NUP98 RGPD2 NUP54	4.59e-05	50	20	3	MM14610
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	NUP98 RGPD2 NUP54	4.87e-05	51	20	3	MM15151
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	NUP98 RGPD2 NUP54	6.11e-05	55	20	3	MM14917
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	NUP98 RGPD2 NUP54	7.17e-05	58	20	3	MM15149
Pathway	REACTOME_SNRNP_ASSEMBLY	NUP98 RGPD2 NUP54	7.17e-05	58	20	3	MM14736
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	NUP98 RGPD2 NUP54	1.01e-04	65	20	3	MM15147
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	NUP98 RGPD2 NUP54	1.43e-04	73	20	3	MM14948
Pathway	REACTOME_GLUCOSE_METABOLISM	NUP98 RGPD2 NUP54	2.01e-04	82	20	3	MM15394
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	NUP98 RGPD2 NUP54	2.16e-04	84	20	3	MM14929
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	NUP98 RGPD2 NUP54	2.32e-04	86	20	3	MM15413
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	NUP98 RGPD2 NUP54	2.83e-04	92	20	3	MM14951
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	CNOT3 CNOT7	2.89e-04	18	20	2	MM15336
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	CNOT3 CNOT7	3.95e-04	21	20	2	M27634
Pathway	REACTOME_TRNA_PROCESSING	NUP98 FTSJ1 NUP54	4.91e-04	111	20	3	M27684
Pathway	REACTOME_DEADENYLATION_OF_MRNA	CNOT3 CNOT7	5.18e-04	24	20	2	MM15090
Pathway	REACTOME_MITOTIC_PROPHASE	NUP98 RGPD2 NUP54	5.31e-04	114	20	3	MM15361
Pathway	REACTOME_DEADENYLATION_OF_MRNA	CNOT3 CNOT7	5.63e-04	25	20	2	M13492
Pathway	REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION	NUP98 NUP54	6.57e-04	27	20	2	M29807
Pathway	REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES	NUP98 SEC24A NUP54	7.11e-04	126	20	3	M45009
Pathway	REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN	NUP98 NUP54	9.25e-04	32	20	2	M29579
Pathway	REACTOME_GENE_SILENCING_BY_RNA	NUP98 TNRC6C NUP54	9.46e-04	139	20	3	M715
Pathway	REACTOME_M_DECAY_DEGRADATION_OF_MATERNAL_MRNAS_BY_MATERNALLY_STORED_FACTORS	CNOT3 CNOT7	9.83e-04	33	20	2	M48026
Pathway	REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS	NUP98 NUP54	9.83e-04	33	20	2	M27016
Pathway	REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN	NUP98 NUP54	1.04e-03	34	20	2	M27041
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	CNOT3 CNOT7	1.04e-03	34	20	2	MM15325
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	NUP98 NUP54	1.11e-03	35	20	2	M27320
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	NUP98 NUP54	1.17e-03	36	20	2	M26974
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	NUP98 NUP54	1.17e-03	36	20	2	M27245
Pathway	REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS	NUP98 NUP54	1.24e-03	37	20	2	M1029
Pathway	REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS	NUP98 NUP54	1.24e-03	37	20	2	M27038
Pathway	REACTOME_METABOLISM_OF_RNA	NUP98 RGPD2 CNOT3 NUP54 CNOT7	1.37e-03	612	20	5	MM15547
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	NUP98 NUP54	1.37e-03	39	20	2	M27238
Pathway	REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS	NUP98 NUP54	1.52e-03	41	20	2	M29574
Pathway	REACTOME_SUMOYLATION	NUP98 RGPD2 NUP54	1.66e-03	169	20	3	MM14919
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	NUP98 NUP54	1.67e-03	43	20	2	M26975
Pathway	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	NUP98 NUP54	1.75e-03	44	20	2	M109
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	NUP98 NUP54	1.91e-03	46	20	2	M27397
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	NUP98 NUP54	1.99e-03	47	20	2	M27395
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	CNOT3 CNOT7	2.16e-03	49	20	2	M27614
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	NUP98 NUP54	2.52e-03	53	20	2	M27212
Pathway	REACTOME_SNRNP_ASSEMBLY	NUP98 NUP54	2.62e-03	54	20	2	M29594
Pathway	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY	CNOT3 CNOT7	2.62e-03	54	20	2	MM15089
Pathway	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY	CNOT3 CNOT7	2.81e-03	56	20	2	M839
Pathway	REACTOME_SARS_COV_2_HOST_INTERACTIONS	NUP98 SEC24A NUP54	2.84e-03	204	20	3	M45011
Pathway	REACTOME_METABOLISM_OF_RNA	NUP98 FTSJ1 CNOT3 NUP54 CNOT7	2.87e-03	724	20	5	M16843
Pathway	REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS	NUP98 NUP54	3.12e-03	59	20	2	M27606
Pathway	KEGG_RNA_DEGRADATION	CNOT3 CNOT7	3.12e-03	59	20	2	M963
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	NUP98 NUP54	4.48e-03	71	20	2	M27394
Pathway	REACTOME_ISG15_ANTIVIRAL_MECHANISM	NUP98 NUP54	4.86e-03	74	20	2	M48006
Pathway	REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY	NUP98 NUP54	5.12e-03	76	20	2	M27215
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	NUP98 NUP54	5.25e-03	77	20	2	M27226
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	NUP98 NUP54	5.93e-03	82	20	2	M27250
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	NUP98 NUP54	6.22e-03	84	20	2	M725
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	NUP98 RGPD2 NUP54	6.29e-03	271	20	3	MM15406
Pathway	REACTOME_GLUCOSE_METABOLISM	NUP98 NUP54	6.36e-03	85	20	2	M1870
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	NUP98 RGPD2 NUP54	6.68e-03	277	20	3	MM15414
Pathway	REACTOME_SARS_COV_2_INFECTION	NUP98 SEC24A NUP54	8.24e-03	299	20	3	M41727
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	NUP98 NUP54	8.54e-03	99	20	2	M27474
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	NUP98 RGPD2	8.71e-03	100	20	2	MM14561
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	NUP98 NUP54	8.88e-03	101	20	2	M27253
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	NUP98 NUP54	9.74e-03	106	20	2	M27458
Pathway	WP_PRADERWILLI_AND_ANGELMAN_SYNDROME	NUP98 NUP54	1.03e-02	109	20	2	M39542
Pathway	REACTOME_HCMV_LATE_EVENTS	NUP98 NUP54	1.16e-02	116	20	2	M29806
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	NUP98 RGPD2	1.18e-02	117	20	2	MM15387
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	CNOT3 CDK19 TNRC6C CNOT7 SCN8A DSC1	1.21e-02	1432	20	6	M509
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	NUP98 RGPD2 CNOT3 NUP54 CNOT7	1.23e-02	1022	20	5	MM15436
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53	CNOT3 TNRC6C CNOT7	1.36e-02	360	20	3	M27267
Pathway	REACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT	CNOT3 CNOT7	1.40e-02	128	20	2	M48019
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	NUP98 RGPD2	1.42e-02	129	20	2	MM14894
Pathway	REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS	NUP98 NUP54	1.46e-02	131	20	2	M5283
Pubmed	miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.	CNOT3 TNRC6C CNOT7	3.02e-08	10	23	3	21984185
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	CNOT3 TNRC6C CNOT7	1.14e-07	15	23	3	21981923
Pubmed	Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome 1p36.31-p36.23.	DNAJC11 CAMTA1	4.18e-07	2	23	2	12964007
Pubmed	Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma.	DNAJC11 CAMTA1	4.18e-07	2	23	2	17222547
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	NUP98 RGPD2 NUP54	2.10e-06	38	23	3	12791264
Pubmed	Human transcription factor protein interaction networks.	NUP98 ZBTB10 CNOT3 SEC24A TNRC6C NUP54 CNOT7 FLG2	2.25e-06	1429	23	8	35140242
Pubmed	Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice.	CNOT3 CNOT7	2.51e-06	4	23	2	21897366
Pubmed	Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats.	NUP98 NUP54	2.51e-06	4	23	2	16651408
Pubmed	The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells.	CNOT3 CNOT7	2.51e-06	4	23	2	27037025
Pubmed	Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.	TNRC6C CNOT7	4.18e-06	5	23	2	19838187
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NUP98 TRO SH2B1 TBC1D5 CAMTA1	7.90e-06	430	23	5	35044719
Pubmed	MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma.	CNOT3 CNOT7	8.77e-06	7	23	2	36112059
Pubmed	Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.	CNOT3 CNOT7	8.77e-06	7	23	2	10637334
Pubmed	Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.	TNRC6C CNOT7	8.77e-06	7	23	2	23340509
Pubmed	Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.	NUP98 NUP54	8.77e-06	7	23	2	8707840
Pubmed	Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.	CNOT3 CNOT7	1.50e-05	9	23	2	21741365
Pubmed	miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.	CNOT3 TNRC6C	2.29e-05	11	23	2	21984184
Pubmed	Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.	CNOT3 CNOT7	2.75e-05	12	23	2	17452450
Pubmed	Human Ccr4-Not complexes contain variable deadenylase subunits.	CNOT3 CNOT7	2.75e-05	12	23	2	19558367
Pubmed	Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation.	CNOT3 CNOT7	2.75e-05	12	23	2	31320642
Pubmed	NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.	CNOT3 CNOT7	3.25e-05	13	23	2	20133598
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	NUP98 RGPD2	3.25e-05	13	23	2	31427429
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	TNRC6C CNOT7	3.79e-05	14	23	2	19716330
Pubmed	High throughput quantitative glycomics and glycoform-focused proteomics of murine dermis and epidermis.	ECM1 DSC1	4.37e-05	15	23	2	16170054
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CNOT3 SEC24A TBC1D5 DNAJC11 TNRC6C CNOT7	4.55e-05	1038	23	6	26673895
Pubmed	Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.	ECM1 FLG2 DSC1	4.79e-05	107	23	3	32989256
Pubmed	Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.	MUC19 ECM1	4.99e-05	16	23	2	19068216
Pubmed	TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.	ECM1 FLG2 DSC1	6.26e-05	117	23	3	36898370
Pubmed	Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse.	CNOT3 CNOT7	6.36e-05	18	23	2	22448252
Pubmed	RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.	CNOT3 CNOT7	7.89e-05	20	23	2	34887419
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	CNOT3 CNOT7	9.59e-05	22	23	2	18377426
Pubmed	Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.	NUP98 NUP54	1.24e-04	25	23	2	10601273
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	NUP98 FTSJ1 DNAJC11 NUP54 FLG2 DSC1	1.31e-04	1257	23	6	36526897
Pubmed	Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.	NUP98 NUP54	1.35e-04	26	23	2	12228227
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TRO CDK19 TNRC6C CAMTA1	1.37e-04	407	23	4	12693553
Pubmed	Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.	FLG2 DSC1	1.80e-04	30	23	2	34905516
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CAMTA1 SCN8A	2.18e-04	33	23	2	22357600
Pubmed	Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.	NUP98 NUP54	3.21e-04	40	23	2	37516964
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	NUP98 SEC24A DSC1	3.47e-04	209	23	3	26389662
Pubmed	Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.	CNOT3 CNOT7	3.72e-04	43	23	2	30733279
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	NUP98 FTSJ1 CNOT3 CNOT7	3.83e-04	533	23	4	25544563
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	CNOT3 CNOT7	3.89e-04	44	23	2	26471122
Pubmed	Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.	CNOT3 CNOT7	4.07e-04	45	23	2	23663784
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	ECM1 FLG2 DSC1	4.24e-04	224	23	3	32941674
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CDK19 TNRC6C CAMTA1	4.30e-04	225	23	3	12168954
Interaction	TNRC6C interactions	CNOT3 SEC24A TNRC6C CNOT7	1.68e-05	138	23	4	int:TNRC6C
Interaction	CNOT6 interactions	CNOT3 TNRC6C CNOT7	3.46e-05	56	23	3	int:CNOT6
Interaction	GARRE1 interactions	CNOT3 TNRC6C NUP54 CNOT7	3.56e-05	167	23	4	int:GARRE1
Interaction	ANXA2R interactions	CNOT3 CNOT7	4.46e-05	9	23	2	int:ANXA2R
Interaction	CNOT8 interactions	CNOT3 TNRC6C CNOT7	7.98e-05	74	23	3	int:CNOT8
Interaction	UNK interactions	NUP98 CNOT3 SEC24A TNRC6C CNOT7	8.26e-05	408	23	5	int:UNK
Interaction	GPBP1L1 interactions	CNOT3 TNRC6C CNOT7	1.25e-04	86	23	3	int:GPBP1L1
Interaction	NUP58 interactions	NUP98 TNRC6C NUP54	1.53e-04	92	23	3	int:NUP58
Interaction	CNOT6L interactions	CNOT3 TNRC6C CNOT7	1.58e-04	93	23	3	int:CNOT6L
Interaction	ETV6 interactions	NUP98 TNRC6C NUP54	2.26e-04	105	23	3	int:ETV6
Interaction	TOB2 interactions	CNOT3 CNOT7	2.34e-04	20	23	2	int:TOB2
Interaction	NANOS1 interactions	CNOT3 CNOT7	2.34e-04	20	23	2	int:NANOS1
Interaction	TNRC6A interactions	ZBTB10 CNOT3 TNRC6C CNOT7	2.62e-04	280	23	4	int:TNRC6A
Interaction	TNRC6B interactions	CNOT3 SEC24A TNRC6C CNOT7	2.69e-04	282	23	4	int:TNRC6B
Interaction	CNOT11 interactions	CNOT3 TNRC6C CNOT7	2.73e-04	112	23	3	int:CNOT11
Interaction	CYLD interactions	MUC19 ECM1 HERC4 TNRC6C FLG2 DSC1	3.37e-04	868	23	6	int:CYLD
Interaction	SPSB4 interactions	SH2B1 TBC1D5 NUP54	3.68e-04	124	23	3	int:SPSB4
Interaction	NANOS2 interactions	CNOT3 CNOT7	3.98e-04	26	23	2	int:NANOS2
Interaction	FANCD2OS interactions	CNOT3 CNOT7	3.98e-04	26	23	2	int:FANCD2OS
Interaction	R3HDM2 interactions	CNOT3 TNRC6C CNOT7	4.13e-04	129	23	3	int:R3HDM2
Interaction	TEX13A interactions	CNOT3 CNOT7	4.30e-04	27	23	2	int:TEX13A
Interaction	CNOT7 interactions	CNOT3 TNRC6C CNOT7	5.25e-04	140	23	3	int:CNOT7
Interaction	CNOT10 interactions	CNOT3 TNRC6C CNOT7	5.36e-04	141	23	3	int:CNOT10
Interaction	CPEB1 interactions	CNOT3 TNRC6C CNOT7	5.93e-04	146	23	3	int:CPEB1
Interaction	NUP43 interactions	NUP98 ZBTB10 MUC19 NUP54 DSC1	5.97e-04	625	23	5	int:NUP43
Interaction	CPEB4 interactions	CNOT3 TNRC6C CNOT7	7.19e-04	156	23	3	int:CPEB4
Interaction	PI4KAP1 interactions	ECM1 FLG2	7.25e-04	35	23	2	int:PI4KAP1
Interaction	GADD45B interactions	CNOT3 CNOT7	7.25e-04	35	23	2	int:GADD45B
Interaction	STYK1 interactions	FTSJ1 SEC24A TBC1D5	7.88e-04	161	23	3	int:STYK1
Interaction	PABPN1L interactions	CNOT3 CNOT7	8.54e-04	38	23	2	int:PABPN1L
Interaction	CNTROB interactions	CNOT3 TNRC6C CNOT7	8.61e-04	166	23	3	int:CNTROB
Interaction	CEP85 interactions	CNOT3 TNRC6C CNOT7	9.07e-04	169	23	3	int:CEP85
GeneFamily	CCR4-NOT transcription complex	CNOT3 CNOT7	5.12e-05	11	18	2	1023
GeneFamily	Nucleoporins	NUP98 NUP54	4.56e-04	32	18	2	1051
Disease	risk-taking behaviour	ZBTB10 SH2B1 TBC1D5 DNAJC11 CDK19	2.62e-04	764	23	5	EFO_0008579
Disease	reaction time measurement	MUC19 CDK19 TNRC6C CAMTA1	1.55e-03	658	23	4	EFO_0008393
Disease	rosacea severity measurement	DNAJC11 CAMTA1	5.82e-03	147	23	2	EFO_0009180

Protein segments in the cluster

Peptide	Gene	Start	Entry
SQQHKQASGGGSSGG	CAMTA1	996	Q9Y6Y1
NSTQTNGTAGGAGAG	CDK19	401	Q9BWU1
QATKNSGSSQGLGGS	SH3BP1	161	Q9Y3L3
SSNSSAGGGAGKQNG	CNOT3	411	O75175
GSGQSTGLGQGESQQ	FLG2	1211	Q5D862
SGSLSTQNGNGGGSI	DNAJC11	181	Q9NVH1
QNQVGAGTTTGLFGS	NUP98	216	P52948
GTTGQSGQGSGTTGK	MUC19	2261	Q7Z5P9
LGGNGQLGTGSTSNR	HERC4	321	Q5GLZ8
NTGTTGLFGGTQNKG	NUP54	46	Q7Z3B4
GLGSGSSYVQNGTGN	CNOT7	261	Q9UIV1
VGTVGGQGIKTQQSF	DSC1	766	Q08554
NAKGQGEQGSTGGTN	ECM1	516	Q16610
GNSNSNSSGGAGTVG	SH2B1	196	Q9NRF2
TGHTKKTNGNNGTNG	TNRC6C	11	Q9HCJ0
GQKNGRGVIFGQTSS	RGPD2	946	P0DJD1
SGQSNYGGSQGSGQT	SEC24A	71	O95486
NGSGEQSKTSNNGGG	SAMSN1	51	Q9NSI8
NGLSTNAGFGGGLNT	TRO	1201	Q12816
NGDFQKNGNGTTSGI	SCN8A	1056	Q9UQD0
SQVLSQKIGGQGSGH	FTSJ1	56	Q9UET6
GGLVTASGGGSTNNN	ZBTB10	16	Q96DT7
CSSGQGQGRGQGQSV	TBC1D5	676	Q92609