Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

HDAC5 GATAD2A PPRC1 MED14 GON4L SSX6P JADE1 MED13L KLHL22 SRRT NCOR1 KMT2C JUND IGF2BP1 IGF2BP3 MRTFB AP2A1 SNAP91 TRIM28 BRD4 BRD7 GAB3 RERE MED13

2.17e-06116014224GO:0030674
GeneOntologyMolecularFunctiontranscription coregulator activity

HDAC5 PPRC1 MED14 GON4L SSX6P JADE1 MED13L NCOR1 KMT2C JUND MRTFB TRIM28 BRD4 BRD7 RERE MED13

2.58e-0656214216GO:0003712
GeneOntologyMolecularFunctionmolecular adaptor activity

HDAC5 GATAD2A PPRC1 MED14 GON4L SSX6P JADE1 MED13L KLHL22 SRRT NCOR1 KMT2C JUND IGF2BP1 IGF2BP3 MRTFB AP2A1 SNAP91 TRIM28 BRD4 PDE4DIP BRD7 GAB3 RERE MED13

9.88e-06135614225GO:0060090
GeneOntologyMolecularFunctiontranscription coactivator activity

PPRC1 MED14 JADE1 KMT2C JUND MRTFB TRIM28 BRD4 BRD7 RERE MED13

1.12e-0530314211GO:0003713
GeneOntologyMolecularFunctionisomerase activity

FKBP15 GSTA1 GSTA2 FKBP7 TOP2A MMUT MPI

4.54e-041921427GO:0016853
GeneOntologyMolecularFunctiondinitrosyl-iron complex binding

GSTA1 GSTA2

4.95e-0451422GO:0035731
GeneOntologyCellularComponentchromatin

FOXS1 HDAC5 GATAD2A BCL7C DRGX NPAS3 NAP1L3 GON4L JADE1 STAT6 NCOR1 KDM4D JUND PRDM10 BBX TRIM28 NFIB BRD4 BRPF1 BRD7 NKX2-2 NKX3-1 INO80B CREB3L2

8.15e-05148014524GO:0000785
GeneOntologyCellularComponentaxoneme

MAP4 TOGARAM1 NME8 GLI1 CFAP161 HYDIN CFAP46 BRWD1

1.01e-042071458GO:0005930
GeneOntologyCellularComponentciliary plasm

MAP4 TOGARAM1 NME8 GLI1 CFAP161 HYDIN CFAP46 BRWD1

1.04e-042081458GO:0097014
GeneOntologyCellularComponenthistone deacetylase complex

HDAC5 GATAD2A MECOM NCOR1 RERE

3.15e-04851455GO:0000118
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

ZC3H14 MAP4 TOGARAM1 NME8 GLI1 CFAP161 HYDIN CFAP46 BRWD1

3.78e-043171459GO:0032838
GeneOntologyCellularComponentcilium

CCP110 MAP4 STARD10 PCDHB15 TOGARAM1 SSX6P JADE1 NME8 TTLL7 GLI1 PCDH15 FHDC1 CFAP161 HYDIN CFAP46 BRWD1

5.11e-0489814516GO:0005929
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

GATAD2A BCL7C GON4L BRD7 INO80B

5.52e-04961455GO:0070603
GeneOntologyCellularComponentactin-based cell projection

STARD10 DAG1 SRCIN1 TEK IGF2BP1 AP2A1 PCDH15 MYO15A

7.33e-042781458GO:0098858
GeneOntologyCellularComponentcytoplasmic region

ZC3H14 MAP4 TOGARAM1 NME8 GLI1 CFAP161 HYDIN CFAP46 BRWD1

9.38e-043601459GO:0099568
DomainBROMODOMAIN_1

TRIM28 BRD4 BRPF1 BRD7 BRWD1

8.48e-06371425PS00633
DomainBROMODOMAIN_2

TRIM28 BRD4 BRPF1 BRD7 BRWD1

1.42e-05411425PS50014
DomainBromodomain

TRIM28 BRD4 BRPF1 BRD7 BRWD1

1.61e-05421425IPR001487
DomainBROMO

TRIM28 BRD4 BRPF1 BRD7 BRWD1

1.61e-05421425SM00297
Domain-

TRIM28 BRD4 BRPF1 BRD7 BRWD1

1.61e-054214251.20.920.10
DomainMed13_N

MED13L MED13

5.74e-0521422PF11597
DomainMediator_Med13_N_met/fun

MED13L MED13

5.74e-0521422IPR021643
DomainMed13_C

MED13L MED13

5.74e-0521422PF06333
DomainMediator_Med13

MED13L MED13

5.74e-0521422IPR009401
DomainBromodomain

BRD4 BRPF1 BRD7 BRWD1

1.93e-04381424PF00439
DomainZnf_PHD-finger

JADE1 KMT2C TAF3 TRIM28 BRPF1

3.40e-04791425IPR019787
DomainSANT

GON4L ZKSCAN2 NCOR1 RERE

5.62e-04501424SM00717
DomainGST_alpha

GSTA1 GSTA2

5.65e-0451422IPR003080
DomainPHD

JADE1 KMT2C TAF3 TRIM28 BRPF1

5.89e-04891425SM00249
DomainEPHD

JADE1 KMT2C BRPF1

5.96e-04221423PS51805
DomainZnf_PHD

JADE1 KMT2C TAF3 TRIM28 BRPF1

6.52e-04911425IPR001965
DomainSANT/Myb

GON4L ZKSCAN2 NCOR1 RERE

6.53e-04521424IPR001005
DomainZF_PHD_2

JADE1 KMT2C TAF3 TRIM28 BRPF1

7.92e-04951425PS50016
DomainZF_PHD_1

JADE1 KMT2C TAF3 TRIM28 BRPF1

8.31e-04961425PS01359
DomainBromodomain_CS

BRD4 BRPF1 BRWD1

9.84e-04261423IPR018359
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NRF1 PPRC1 PIEZO1 MED14 JADE1 TNRC6C MED13L PLXNB2 NHSL1 NCOR1 KMT2C ZNF263 JUND SH3PXD2B AP2A1 ADAMTS7 PLEKHM2 TRIM28 GLI1 BRD4 PPP1R15B MED13 AHNAK2

2.56e-1011051462335748872
Pubmed

Interaction network of human early embryonic transcription factors.

HDAC5 BCL7C MECOM UBN2 NCOR1 KMT2C ZNF263 TAF3 ZNF608 NFIB BRD7 RERE TOP2A

3.43e-093511461338297188
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL7C MED14 MED13L UBN2 NCOR1 ZNF608 NFIB BRD4 BRD7 RERE MED13

2.03e-082681461133640491
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ZC3H14 MAP4 MED14 UBN2 SCYL2 NCOR1 KMT2C SH3PXD2B TAF3 MRTFB TRIM28 BRD4 PRRC2A TOP2A

9.08e-085491461438280479
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZC3H14 GATAD2A MAP4 ZC3H13 UBN2 CDCA8 SRRT NCOR1 IGF2BP1 TAF3 BBX SNAP91 TRIM28 BRD4 BRD7 PRRC2A TOP2A INO80B

1.16e-079541461836373674
Pubmed

DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

MED13L PPP1R15B CDC25B PRRC2A MED13

3.57e-0735146526091241
Pubmed

Human transcription factor protein interaction networks.

HDAC5 GATAD2A BCL7C GON4L MECOM TNRC6C UBN2 SRRT NCOR1 KMT2C JUND IGF2BP1 IGF2BP3 TAF3 BBX ZNF608 NFIB BRD7 RERE PRRC2A INO80B

6.05e-0714291462135140242
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MPP2 FKBP15 CACNB4 DSCAM UBN2 RTN1 ITIH1 NCOR1 ZNF263 SH3PXD2B AP2A1 SNAP91 TRIM28 PDE4DIP BRD7 MACF1 PRRC2A

6.74e-079631461728671696
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXS1 HDAC5 GATAD2A NRF1 NPAS3 MECOM E4F1 TTLL7 CRACD NCOR1 JUND PRDM10 BBX GLI1 TOP2A NOVA2

7.09e-078571461625609649
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CCP110 ZC3H14 HDAC5 GATAD2A BCL7C KMT2C TAF3 TRIM28 BRD4 BRD7 HYDIN TOP2A

7.58e-074691461227634302
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

GATAD2A TRIM28 BRD4 BRPF1 BRD7 BRWD1

7.83e-0775146625593309
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MAP4 ZC3H13 BCL7C MED14 SRRT NCOR1 JUND TAF3 TRIM28 BRD4 BRPF1 RERE PRRC2A TOP2A MED13

1.02e-067741461515302935
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GATAD2A BTBD18 BCL7C MECOM ZKSCAN2 TAF3 ZNF608 TRIM28 BRD4 BRPF1 BRD7 MACF1 RERE TOP2A INO80B CDH16 NOVA2 BRWD1

1.13e-0611161461831753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FKBP15 HDAC5 PPRC1 GON4L TNRC6C MED13L CRACD PLEKHM2 PDE4DIP MACF1 RERE

1.31e-064071461112693553
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXS1 DRGX NPAS3 GON4L ZKSCAN2 E4F1 STAT6 JUND BBX MZF1 NFIB GLI1 NKX2-2 NKX3-1 RERE CREB3L2

1.50e-069081461619274049
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

TOM1L2 MPP2 CACNB4 MAP4 SRCIN1 RTN1 AP2A1 SNAP91 MACF1 PRRC2A

2.29e-063471461017114649
Pubmed

Proteomic analysis of in vivo phosphorylated synaptic proteins.

CACNB4 MAP4 SRCIN1 RTN1 AP2A1

2.97e-0653146515572359
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CCP110 KIAA1191 RTN1 NHSL1 IGF2BP3 MAST4 ROBO1 MACF1

3.08e-06209146836779422
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZC3H14 MAP4 PIEZO1 MED14 GON4L E4F1 UBN2 SRRT CRACD KMT2C MRTFB BBX NFIB NMT2 BRD7 MACF1 INTS9 PRRC2A MED13 INO80B

4.85e-0614971462031527615
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

GATAD2A MED14 KMT2C MED13 AHNAK2

5.08e-0659146528813667
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HDAC5 TOGARAM1 TNRC6C MED13L KMT2C MRTFB ZNF608 MACF1

5.31e-06225146812168954
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

PCDH15 ROBO1 MYO15A

5.98e-069146323144817
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CCP110 GON4L NEB IGF2BP1 IGF2BP3 BRPF1 MACF1 TOP2A

7.07e-06234146836243803
Pubmed

Functional proteomics mapping of a human signaling pathway.

TOM1L2 E4F1 SCYL2 NCOR1 MTMR11 MRTFB MAST4 AP2A1 BRD4 PPP1R15B PDE4DIP MACF1

8.10e-065911461215231748
Pubmed

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.

GSTA1 GSTA2 NCOR1

8.51e-0610146315870285
Pubmed

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.

MED14 MED13L MED13

8.51e-0610146323746844
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZC3H14 GATAD2A ZC3H13 MECOM E4F1 UBN2 SRRT NCOR1 KMT2C JUND BBX AP2A1 TRIM28 NFIB BRD4 INTS9 TOP2A CREB3L2

8.76e-0612941461830804502
Pubmed

The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.

SRRT ZNF263 TRIM28 NFIB TOP2A

8.85e-0666146532051553
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

GATAD2A BCL7C UBN2 CDCA8 TAF3 BBX BRD4 BRPF1 BRD7 ZNF649 TOP2A BRWD1

1.07e-056081461236089195
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

CCP110 HDAC5 ZC3H13 PIEZO1 PAQR8 DAG1 RUSC1 GON4L MECOM KIAA1191 PLXNB2 SCYL2 ZNF608 MED13 INO80B CFAP46 CREB3L2

1.47e-0512151461715146197
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

GATAD2A BCL7C MED14 TAF3 BBX AP2A1 TRIM28 BRD4 INTS9 TOP2A NOVA2

1.68e-055331461130554943
Pubmed

Polymorphism of human Alpha class glutathione transferases.

GSTA1 GSTA2

1.75e-052146211668220
Pubmed

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.

GSTA1 GSTA2

1.75e-05214623800996
Pubmed

Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.

GSTA1 GSTA2

1.75e-05214623678589
Pubmed

The basic glutathione S-transferases from human livers are products of separate genes.

GSTA1 GSTA2

1.75e-05214623036131
Pubmed

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells.

PCDH15 MYO15A

1.75e-052146224940003
Pubmed

The extended catalysis of glutathione transferase.

GSTA1 GSTA2

1.75e-052146221163259
Pubmed

Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.

GSTA1 GSTA2

1.75e-052146215128049
Pubmed

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

STAT6 NCOR1

1.75e-052146229343442
Pubmed

Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.

GSTA1 GSTA2

1.75e-052146211692074
Pubmed

A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA.

IGF2BP1 GLI1

1.75e-052146230790682
Pubmed

FOXS1 promotes prostate cancer progression through the Hedgehog/Gli1 pathway.

FOXS1 GLI1

1.75e-052146237890593
Pubmed

Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other Alpha class glutathione S-transferases.

GSTA1 GSTA2

1.75e-05214622604726
Pubmed

BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene.

BRD4 MMP2

1.75e-052146232499570
Pubmed

Nuclear transit of human zipcode-binding protein IMP1.

IGF2BP1 IGF2BP3

1.75e-052146212921532
Pubmed

The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis.

IGF2BP1 IGF2BP3

1.75e-052146211992722
Pubmed

Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.

GSTA1 GSTA2

1.75e-05214623031680
Pubmed

Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse.

MED13L MED13

1.75e-052146229325037
Pubmed

Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.

MMP2 TNXB

1.75e-052146215212943
Pubmed

Inhibition of GLI1 Expression by Targeting the CRD-BP-GLI1 mRNA Interaction Using a Specific Oligonucleotide.

IGF2BP1 GLI1

1.75e-052146227036131
Pubmed

Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.

GSTA1 GSTA2

1.75e-052146221844655
Pubmed

Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities.

GSTA1 GSTA2

1.75e-05214623138230
Pubmed

Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line.

GSTA1 GSTA2

1.75e-05214621330133
Pubmed

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.

GSTA1 GSTA2

1.75e-052146219639209
Pubmed

Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.

MZF1 MMP2

1.75e-052146222846578
Pubmed

Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver.

GSTA1 GSTA2

1.75e-05214628431482
Pubmed

TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation.

TRIM28 BRD7

1.75e-052146239222175
Pubmed

RNA-binding IMPs promote cell adhesion and invadopodia formation.

IGF2BP1 IGF2BP3

1.75e-052146216541107
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CCP110 MED14 GON4L MECOM MED13L UBN2 CDCA8 IGF2BP3 BBX AP2A1 ZNF608 MED13

1.93e-056451461225281560
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZC3H14 GATAD2A MAP4 MED14 CDCA8 SRRT IGF2BP1 IGF2BP3 AP2A1 TRIM28 MACF1 PRRC2A TOP2A

2.04e-057591461335915203
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

FOXS1 HDAC5 E4F1 JADE1 STAT6 ZNF263 JUND MZF1 TRIM28 GLI1 BRPF1 BRD7 NKX2-2 RERE

2.11e-058771461420211142
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

TOM1L2 ZC3H14 SRRT IGF2BP1 AP2A1 NFIB ROBO1 MACF1 TOP2A

2.20e-05358146932460013
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ZC3H14 FKBP15 GATAD2A MAP4 MED14 MED13L SRRT NCOR1 TAF3 TRIM28 NFIB BRD4 MYO15A TOP2A MED13

2.56e-0510141461532416067
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

GATAD2A MAP4 NCOR1 MRTFB BBX TRIM28 BRD4 TOP2A

2.78e-05283146830585729
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ZC3H14 ZC3H13 NAP1L3 DAG1 MECOM NDFIP2 CDCA8 MFSD14A SRRT IGF2BP1 IGF2BP3 BRD7 PRRC2A MED13

3.64e-059221461427609421
Pubmed

Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.

GSTA1 GSTA2 JUND

3.90e-051614638649810
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZC3H14 FKBP15 MAP4 RTN1 SCYL2 CRACD IGF2BP1 IGF2BP3 MRTFB TRIM28 MACF1 PRRC2A TOP2A AHNAK2

4.19e-059341461433916271
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

GATAD2A JADE1 UBN2 TOP2A BRWD1

4.23e-0591146520362542
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SRRT NCOR1 KMT2C TRIM28 NFIB NKX3-1 RERE

4.24e-05220146735785414
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

GATAD2A GON4L MECOM KMT2C ZNF608 NFIB BRD4 BRD7 MYO15A

5.01e-05398146935016035
Pubmed

Mapping of unconventional myosins in mouse and human.

GSTA1 GSTA2 JUND GLI1

5.02e-054814648884266
Pubmed

Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms.

IGF2BP1 IGF2BP3

5.24e-053146217296566
Pubmed

Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA.

IGF2BP1 GLI1

5.24e-053146219887615
Pubmed

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

BRD4 TOP2A

5.24e-053146228813519
Pubmed

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.

IGF2BP1 IGF2BP3

5.24e-053146229476152
Pubmed

METTL3-Mediated RNA m6A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2.

TEK MMP2

5.24e-053146237819742
Pubmed

Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells.

NRF1 PPRC1

5.24e-053146211340167
Pubmed

Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells.

NRF1 PPRC1

5.24e-053146211943463
Pubmed

Initiation of stress granule assembly by rapid clustering of IGF2BP proteins upon osmotic shock.

IGF2BP1 IGF2BP3

5.24e-053146232668274
Pubmed

Identification of Pathogenic Genes of Nonsyndromic Hearing Loss in Uyghur Families Using Massively Parallel DNA Sequencing Technique.

PCDH15 MYO15A

5.24e-053146229692870
Pubmed

MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains.

DAG1 MMP2

5.24e-053146221865464
Pubmed

IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes.

IGF2BP1 IGF2BP3

5.24e-053146220627640
Pubmed

FOXS1 is regulated by GLI1 and miR-125a-5p and promotes cell proliferation and EMT in gastric cancer.

FOXS1 GLI1

5.24e-053146230918291
Pubmed

Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer.

IGF2BP1 IGF2BP3

5.24e-053146216049158
Pubmed

Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion.

MMP2 TNXB

5.24e-053146212419962
Pubmed

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

IGF2BP1 IGF2BP3

5.24e-05314629891060
Pubmed

Comparative expression of two alpha class glutathione S-transferases in human adult and prenatal liver tissues.

GSTA1 GSTA2

5.24e-053146212093480
Pubmed

Interaction analysis of miR-1275/IGF2BP1/IGF2BP3 with the susceptibility to hepatocellular carcinoma.

IGF2BP1 IGF2BP3

5.24e-053146232134323
Pubmed

Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.

BRD4 CDK6

5.24e-053146230518851
Pubmed

VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins.

IGF2BP1 IGF2BP3

5.24e-053146215601260
Pubmed

Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation.

STAT6 GLI1

5.24e-053146212049724
Pubmed

ZBP1 recognition of beta-actin zipcode induces RNA looping.

IGF2BP1 IGF2BP3

5.24e-053146220080952
Pubmed

Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.

IGF2BP1 GLI1

5.24e-053146217925019
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TOM1L2 MAP4 PPRC1 ZC3H13 DAG1 JADE1 UBN2 STAT6 MFSD14A KMT2C SH3PXD2B GLI1 MACF1 CDK6 BRWD1

5.47e-0510841461511544199
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

CCP110 GATAD2A MAP4 ZC3H13 SRRT NCOR1 IGF2BP1 TRIM28 PRRC2A TOP2A

5.62e-055031461016964243
Pubmed

The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.

GLI1 ROBO1 NKX2-2

5.65e-0518146316854408
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ZC3H14 GATAD2A ZC3H13 SCYL2 NCOR1 JUND IGF2BP3 TRIM28 NFIB BRPF1 PRRC2A TOP2A INO80B

6.27e-058471461335850772
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZC3H14 GATAD2A MAP4 MED14 MED13L UBN2 CCDC7 NCOR1 KMT2C JUND IGF2BP1 IGF2BP3 BRD4 PRRC2A TOP2A

6.64e-0511031461534189442
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

GATAD2A ZC3H13 IGF2BP1 IGF2BP3 PRRC2A

6.97e-05101146526949739
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCP110 MAP4 USP43 KIAA1191 NHSL1 SRRT SH3PXD2B MAST4 PI4KB BRD4 MACF1 CDC25B AHNAK2

7.40e-058611461336931259
InteractionSSRP1 interactions

ZC3H14 GATAD2A ZC3H13 MECOM JADE1 TEK RTN1 SRRT NCOR1 IGF2BP1 IGF2BP3 TRIM28 BRD4 BRPF1 BRD7 INTS9 PRRC2A TOP2A BRWD1

2.83e-0768514019int:SSRP1
InteractionH3C14 interactions

MECOM JADE1 CDCA8 STAT6 KMT2C BRD4 BRPF1 BRD7 RERE

1.46e-061561409int:H3C14
InteractionEGR2 interactions

HDAC5 MECOM UBN2 NCOR1 KMT2C ZNF608 PDE4DIP BRD7 RERE

3.12e-061711409int:EGR2
InteractionTLX1 interactions

BCL7C UBN2 NCOR1 KMT2C IGF2BP1 IGF2BP3 ZNF608 NFIB BRD7

3.78e-061751409int:TLX1
InteractionNUP43 interactions

GATAD2A DSCAM MAP4 ZC3H13 GON4L UBN2 CDCA8 SRRT NCOR1 TAF3 MRTFB BBX ZNF608 RERE TOP2A AHNAK2

7.34e-0662514016int:NUP43
InteractionSP7 interactions

BCL7C SRRT NCOR1 KMT2C IGF2BP1 IGF2BP3 ZNF608 NFIB BRD7 RERE FAM124B

9.28e-0630414011int:SP7
InteractionCENPA interactions

GATAD2A ZC3H13 MECOM UBN2 CDCA8 SRRT TAF3 BBX BRPF1 BRD7 TOP2A BRWD1

1.31e-0537714012int:CENPA
InteractionSOX6 interactions

GATAD2A MECOM UBN2 NCOR1 IGF2BP1 IGF2BP3 NFIB PRRC2A

1.42e-051571408int:SOX6
InteractionAR interactions

TOM1L2 BCL7C MED14 MED13L UBN2 SRRT NCOR1 KMT2C KDM4D ZNF608 TRIM28 NFIB BRD4 BRD7 NKX3-1 RERE REPS2 CDC25B MED13 CDK6

1.74e-0599214020int:AR
InteractionHNF4A interactions

HDAC5 BCL7C MED14 UBN2 NCOR1 KMT2C TAF3 ZNF608 NFIB BRD7

2.30e-0527514010int:HNF4A
InteractionTOP3B interactions

NRF1 PPRC1 PIEZO1 MED14 JADE1 TNRC6C MED13L PLXNB2 NHSL1 NCOR1 KMT2C ZNF263 JUND IGF2BP1 SH3PXD2B AP2A1 ADAMTS7 PLEKHM2 TRIM28 GLI1 BRD4 PPP1R15B PRRC2A MED13 AHNAK2

2.57e-05147014025int:TOP3B
InteractionMED14 interactions

ZC3H13 MED14 MED13L CDCA8 TRIM28 BRD4 INTS9 MED13

2.63e-051711408int:MED14
InteractionKLF15 interactions

NRF1 NCOR1 KMT2C IGF2BP1 IGF2BP3 ZNF608 GLI1 BRD7 PRRC2A MMUT

3.61e-0529014010int:KLF15
InteractionHNRNPUL2 interactions

FOXS1 ZC3H14 MECOM TNRC6C TEK SRRT IGF2BP1 IGF2BP3 BRD4 TOP2A

3.72e-0529114010int:HNRNPUL2
InteractionBRD2 interactions

GATAD2A BCL7C MECOM ZNF263 TAF3 BRD4 NMT2 BRPF1 BRD7 TOP2A INO80B NOVA2

4.65e-0542914012int:BRD2
InteractionMED25 interactions

ZC3H13 MED14 RUSC1 BRD4 TOP2A MED13

4.69e-05931406int:MED25
InteractionSOX9 interactions

HDAC5 BCL7C UBN2 KMT2C BRD4 BRD7

5.94e-05971406int:SOX9
InteractionNFIB interactions

BCL7C NCOR1 KMT2C ZNF263 ZNF608 NFIB BRD4

6.12e-051421407int:NFIB
InteractionMED27 interactions

ZC3H13 MED14 MED13L BRD4 TOP2A MED13

7.86e-051021406int:MED27
InteractionFEV interactions

MECOM UBN2 NCOR1 KMT2C TAF3 ZNF608 NFIB BRD7

8.86e-052031408int:FEV
InteractionMEN1 interactions

ZC3H14 GATAD2A ZC3H13 MED14 SCYL2 SRRT NCOR1 KMT2C JUND IGF2BP3 MRTFB ZNF608 TRIM28 NFIB BRPF1 INTS9 RERE PRRC2A TOP2A

9.36e-05102914019int:MEN1
InteractionMED26 interactions

ZC3H13 MED14 MED13L TAF3 BRD4 MED13

1.03e-041071406int:MED26
InteractionMED23 interactions

ZC3H13 MED14 MECOM MED13L AP2A1 ZNF608 BRD4 INTS9 MED13

1.03e-042661409int:MED23
InteractionEN1 interactions

NAP1L3 UBN2 NCOR1 KMT2C ZNF608 NFIB

1.20e-041101406int:EN1
InteractionPAX8 interactions

BCL7C JADE1 NCOR1 KMT2C ZNF608 NFIB

1.26e-041111406int:PAX8
InteractionTBR1 interactions

BCL7C NCOR1 KMT2C ZNF608 NFIB BRD4

1.39e-041131406int:TBR1
InteractionSOX5 interactions

GATAD2A NCOR1 IGF2BP1 ZNF608 NFIB PRRC2A CDK6

1.40e-041621407int:SOX5
InteractionLHX4 interactions

NRF1 BCL7C NCOR1 KMT2C NFIB BRD7 INO80B

1.63e-041661407int:LHX4
InteractionCBX3 interactions

CACNB4 ZC3H13 MECOM UBN2 CDCA8 SRRT NCOR1 ZNF263 PRDM10 BBX TRIM28 BRD4 MACF1 TOP2A

1.66e-0464614014int:CBX3
InteractionH3C1 interactions

HDAC5 GATAD2A MED14 MECOM JADE1 NEB UBN2 CDCA8 NCOR1 KMT2C TAF3 BBX TRIM28 BRD4 BRPF1 BRD7 TOP2A

1.74e-0490114017int:H3C1
InteractionRBM11 interactions

MECOM MED13L KLHL22 SCYL2 SRRT NMT2 PRRC2A

1.82e-041691407int:RBM11
InteractionMRE11 interactions

MECOM ZNF263 IGF2BP3 TRIM28 GLI1 BRD4 NKX3-1 CFAP161 TOP2A

1.83e-042871409int:MRE11
InteractionSMC5 interactions

ZC3H14 GATAD2A MAP4 ZC3H13 UBN2 CDCA8 SRRT NCOR1 IGF2BP1 TAF3 BBX SNAP91 TRIM28 BRD4 BRD7 PRRC2A TOP2A INO80B

1.99e-04100014018int:SMC5
InteractionMED8 interactions

ZC3H13 MED14 MED13L BRD4 INTS9 MED13

2.02e-041211406int:MED8
InteractionH3-3A interactions

HDAC5 GATAD2A BCL7C UBN2 CDCA8 KMT2C TAF3 BBX TRIM28 BRD4 BRPF1 BRD7 ZNF649 TOP2A BRWD1

2.28e-0474914015int:H3-3A
InteractionCDK1 interactions

CCP110 HDAC5 NRF1 MAP4 SCYL2 IGF2BP3 TRIM28 GLI1 BRD4 REPS2 CDC25B TOP2A CDK6

2.45e-0459014013int:CDK1
InteractionPAX6 interactions

DSCAM BCL7C DRGX UBN2 NCOR1 KMT2C TAF3 ZNF608 NFIB BRD7

2.45e-0436614010int:PAX6
InteractionSENP3 interactions

CCP110 ZC3H14 CDCA8 BBX SNAP91 TRIM28 BRD4 BRD7 CDK6

2.60e-043011409int:SENP3
Cytoband6p12.1

PAQR8 GSTA1 GSTA2

1.60e-043314636p12.1
GeneFamilyPHD finger proteins

JADE1 KMT2C TAF3 TRIM28 BRPF1

1.01e-049093588
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GON4L ZKSCAN2 NCOR1 RERE

1.58e-0453934532
GeneFamilyCyclins|Mediator complex

MED14 MED13L MED13

6.43e-04339331061
GeneFamilyFibronectin type III domain containing

DSCAM COL20A1 TEK ROBO1 TNXB

1.42e-03160935555
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 NCOR1 TRIM28 PPP1R15B HYDIN

2.43e-03181935694
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATAD2A RERE

2.63e-031593282
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

MECOM PRDM10

3.39e-03179321197
GeneFamilyFKBP prolyl isomerases

FKBP15 FKBP7

3.80e-0318932910
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

FKBP15 CACNB4 DSCAM MFSD6 PAQR8 NPAS3 NAP1L3 RUSC1 SRCIN1 TNRC6C MED13L NEB UBN2 RTN1 TTLL7 MAST4 SNAP91 PDE4DIP ROBO1 HYDIN AHNAK2 BRWD1

1.51e-07110614322M39071
CoexpressionGSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP

FOXS1 NRF1 DAG1 NEB SRRT PLEKHM2 TRIM28 PI4KB

1.42e-051991438M7325
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MECOM TEK KMT2C MRTFB MAST4 ZNF608 NFIB MACF1 FAM124B BRWD1

1.26e-0920014610dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPSE2 NME8 CCDC7 SNAP91 PCDH15 ATP12A MYO15A HYDIN EDDM13

1.30e-09145146996712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGS22 DAG1 RTN1 NHSL1 NFIB ROBO1 TOP2A BORA

9.10e-0816914682833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MECOM TEK MRTFB MAST4 ZNF608 NFIB MACF1 FAM124B

2.62e-0719414680b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

VWA3A GSTA1 MAST4 NFIB MACF1 HYDIN TOP2A CFAP46

2.83e-071961468af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

VWA3A GSTA1 MAST4 NFIB MACF1 HYDIN TOP2A CFAP46

2.83e-0719614686d02d494196e3f857d53eea46d9419690d43beca
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

HPSE2 CRACD JUND IGF2BP1 IGF2BP3 NFIB MMP2 CDK6

3.18e-0719914685b9d355795dd03a22f0961dfd143425c367a4654
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MECOM TEK MRTFB MAST4 ZNF608 NFIB MACF1 FAM124B

3.30e-072001468a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM161B DAG1 SCNN1G ROBO1 NKX3-1 MYO15A CDK6

1.40e-061681467ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWA3A RGS22 FHDC1 CFAP161 HYDIN CFAP46 EDDM13

1.98e-061771467d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWA3A RGS22 FHDC1 CFAP161 HYDIN CFAP46 EDDM13

1.98e-061771467d5640f0097878f0dac671e51dc51310278bb2682
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A CCP110 RGS22 USP43 TTLL7 HYDIN CFAP46

2.22e-06180146792fb01b91261b3103454924cde56add337b41844
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VWA3A MECOM NFIB PCDH15 GAB3 ROBO1 MMP2

2.85e-06187146713731298bc562ec29582f5da1b4c97261284f6f1
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

VWA3A MECOM GSTA1 GSTA2 HYDIN CFAP46 AHNAK2

3.28e-061911467ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

VWA3A MECOM GSTA1 GSTA2 HYDIN CFAP46 AHNAK2

3.28e-0619114676228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PIEZO1 CDCA8 SRRT NCOR1 BRD4 TOP2A AHNAK2

3.40e-0619214679cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MECOM TEK MRTFB MAST4 ZNF608 NFIB FAM124B

3.51e-0619314676e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCA8 CFAP161 CDC25B FAM124B TOP2A NOVA2 BORA

4.02e-061971467491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

CCP110 NRF1 RGS22 LGALS12 ZNF608 NMT2 TOP2A

4.02e-061971467038fd92750257d43d5e980fd06d77742b543f11a
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-0619914671ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-0619914671df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-06199146781115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-06199146774087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-06199146700b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-061991467ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

ZC3H13 JADE1 NCOR1 BBX BRD4 BRD7 BRWD1

4.30e-061991467c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-06199146791308b255783ad4029e5575028c18d7550832c51
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

VWA3A MECOM GSTA1 GSTA2 NFIB HYDIN CFAP46

4.30e-06199146772689bda7476930887ae007682fcab27f956f050
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

RUSC1 SRCIN1 UBN2 RTN1 CRACD NMT2 PDE4DIP

4.44e-062001467bad32a95b759fad509401b07bc96a56687c2a592
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

TEK IGF2BP3 MRTFB ZNF608 NFIB MACF1 FAM124B

4.44e-0620014673b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 ZC3H13 NAP1L3 RTN1 NCOR1 PDE4DIP MMP2

4.44e-062001467e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MECOM TEK IGF2BP3 MRTFB ZNF608 NFIB FAM124B

4.44e-062001467b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

GSTA1 IGF2BP1 NFIB SCNN1G CHRNA10 ATP12A

9.14e-0614714665a824c89e4d045af465d7333275f8191fb29b041
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)|lymph-node_spleen / Manually curated celltypes from each tissue

NEB CRACD IGF2BP1 IGF2BP3 ZNF608 REPS2

1.11e-0515214664f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

TOM1L2 NAP1L3 HPSE2 TNRC6C TAF3 PCDH15

1.53e-051611466347edb0de10850b7d16c40945751033289289c9b
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HPSE2 NEB SNAP91 PCDH15 ATP12A HYDIN

1.59e-051621466bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GARIN1A ABHD6 MECOM IGF2BP1 FHDC1 HYDIN

1.76e-051651466936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellCiliated_cells-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

VWA3A RGS22 SRCIN1 CFAP161 HYDIN CFAP46

1.89e-051671466edb722ee9b6ccd00fb038f702be8664020932659
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRSS57 NAP1L3 MECOM CRACD FAM124B CDK6

2.09e-0517014665bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA8 ADAMTS7 NFIB MMP2 TOP2A BORA

2.23e-051721466c06ca5d075937747952ed915c9db39a9f62072f9
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGS22 FHDC1 CFAP161 HYDIN CFAP46 EDDM13

2.30e-051731466a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRSS57 NAP1L3 MECOM CRACD FAM124B CDK6

2.38e-05174146666df78280f657978c4a568010ae7d7943869af90
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TTLL7 MAST4 ADAMTS7 NMT2 FKBP7 FAM124B

2.46e-051751466bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA8 ADAMTS7 NFIB MMP2 TOP2A BORA

2.46e-051751466a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

PCDHB15 HPSE2 KLHL22 KDM4D ROBO1 MMP2

2.62e-051771466e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PCDHB15 HPSE2 KLHL22 KDM4D ROBO1 MMP2

2.62e-05177146643ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

FKBP15 MECOM SRCIN1 TEK MAST4 BRD4

2.62e-051771466b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCellsevere-Others-CD34+_GATA2+_cells|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PRSS57 NAP1L3 MECOM MMP2 FAM124B CDK6

2.79e-051791466dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

DSCAM TEK PLXNB2 RTN1 NHSL1 SH3PXD2B

2.88e-0518014667be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PRSS57 MECOM CRACD MMP2 FAM124B CDK6

2.97e-051811466070ae3f3fe0e177fabcf34e64a0f158b01354837
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS22 NEB PCDH15 ROBO1 MYO15A HYDIN

3.25e-0518414662cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

PRSS57 MECOM TEK CRACD NFIB CDK6

3.25e-051841466b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS22 NEB PCDH15 ROBO1 MYO15A HYDIN

3.25e-051841466ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS22 NEB PCDH15 ROBO1 MYO15A HYDIN

3.25e-0518414662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPAS3 MECOM ZNF608 SCNN1G ATP12A CDK6

3.35e-051851466d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWA3A MECOM NFIB PCDH15 ROBO1 MMP2

3.35e-0518514669f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

3.46e-051861466f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell(8)_CD34_progenitor|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PRSS57 MECOM NFIB MMP2 FAM124B CDK6

3.46e-051861466943c604a7cd873faf510096d094100512ba2d6bc
ToppCell(8)_CD34_progenitor|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PRSS57 MECOM NFIB MMP2 FAM124B CDK6

3.46e-051861466e69a986b8618effd61875fda528a2e44aab11868
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A SRCIN1 FHDC1 CFAP161 HYDIN CFAP46

3.56e-0518714660334fb1247a5800bf1438a48da8fd905df000d89
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

3.56e-051871466f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

VWA3A RGS22 GSTA2 CFAP161 HYDIN CFAP46

3.56e-0518714661a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A RGS22 GSTA1 CFAP161 HYDIN CFAP46

3.56e-051871466e61992de4f98eeea08b43213850769d923f8db48
ToppCelldroplet-Lung-LUNG-1m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A SRCIN1 FHDC1 CFAP161 HYDIN CFAP46

3.56e-051871466cf8e3448402e1d05b8321a5f124bd29e30e18841
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

VWA3A RGS22 GSTA1 HYDIN CFAP46 AHNAK2

3.67e-051881466606907c865bd2f11bb6474932716550f7723d858
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

3.78e-051891466c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

PRSS57 NAP1L3 MECOM CRACD MMP2 CDK6

3.78e-051891466555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 NPAS3 MECOM SCNN1G REPS2 CDK6

3.78e-051891466fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PRSS57 MECOM CRACD MMP2 FAM124B CDK6

3.78e-0518914666687a93ac8540ece5fd762f6f77c1f25f159195b
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFIB GLI1 ROBO1 FKBP7 MMP2 TOP2A

3.78e-0518914663169476f98b7385706cb618c9ad64ae83a290ef0
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CACNB4 NPAS3 MECOM JUND NFIB ROBO1

4.13e-051921466d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

PRSS57 MECOM TEK CRACD FAM124B CDK6

4.13e-051921466cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

VWA3A CCP110 RGS22 GSTA1 HYDIN CFAP46

4.25e-051931466c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JADE1 CDCA8 ROBO1 CDC25B TOP2A BORA

4.25e-051931466a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A MRTFB ZNF608 HYDIN CFAP46 AHNAK2

4.25e-051931466ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MECOM TEK MRTFB ZNF608 NFIB FAM124B

4.25e-051931466af5108260783e69a7d67896c5bf64f862525926d
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RTN1 JUND IGF2BP3 NFIB MMP2 CDK6

4.37e-0519414668b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWA3A CCP110 RGS22 GSTA1 HYDIN CFAP46

4.37e-0519414665aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

VWA3A RGS22 MAST4 NFIB HYDIN CFAP46

4.50e-05195146621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL7 NCOR1 KMT2C MACF1 NKX2-2 RERE

4.50e-0519514663e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL7 NCOR1 KMT2C MACF1 NKX2-2 RERE

4.50e-0519514667796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

STARD10 SH3PXD2B MRTFB SCNN1G ATP12A CDK6

4.76e-05197146678ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A RGS22 USP43 SRCIN1 HYDIN CFAP46

4.76e-05197146674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

TEK MRTFB ZNF608 NFIB PCDH15 NOVA2

4.76e-0519714667e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCA8 CDC25B FAM124B TOP2A NOVA2 BORA

4.76e-0519714668e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA8 NFIB MMP2 CDC25B TOP2A BORA

4.76e-05197146629b0a5927f80455eef7b793feabef69fba1a3df1
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

HPSE2 CRACD SH3PXD2B ROBO1 MACF1 MMP2

4.76e-051971466f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA8 NFIB GLI1 ROBO1 MMP2 TOP2A

4.90e-051981466148f5fee19ea8dff7f2de4ca69c3b03e5221985d
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

5.03e-0519914662de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCelldistal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

5.03e-0519914667e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCelldistal-Epithelial-Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA3A RGS22 GSTA1 GSTA2 HYDIN CFAP46

5.03e-0519914666ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB4 PIEZO1 SCNN1G MACF1 CDH16 CDK6

5.03e-0519914663cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VWA3A RGS22 GSTA2 CFAP161 HYDIN CFAP46

5.18e-05200146652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC|GW26 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 CDCA8 PCDH15 NKX2-2 MMP2 TOP2A

5.18e-05200146602594c1edbc9f2cf831639cd83363abd2551cb94
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VWA3A RGS22 GSTA2 CFAP161 HYDIN CFAP46

5.18e-05200146655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MECOM TEK MAST4 FAM124B CDH16 NOVA2

5.18e-0520014665ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related|GW26 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 CDCA8 PCDH15 NKX2-2 MMP2 TOP2A

5.18e-05200146646521d83b917b0357601db8783c8da6b73730d60
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

NFIB GLI1 GAB3 ROBO1 MMP2 TNXB

5.18e-052001466a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell(03)_Secretory-(1)_24hpi|(03)_Secretory / shred by cell type and Timepoint

FOXS1 CCP110 CDCA8 TOP2A AHNAK2

8.30e-0513514656e473296dfe1ff7a63d701e56920c0a1b043ddc6
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-Neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

RTN1 NFIB SCNN1G FKBP7 FHDC1

8.59e-051361465b46450292e0cd549eb3bafdd3fed22f41d85bfbe
DrugAlprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A

FKBP15 DSCAM NRF1 MAP4 ABHD6 MZF1 NFIB PDE4DIP AKAP10

3.61e-0619214393188_DN
DrugTriflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A

MPP2 PIGN STAT6 KLHL22 SRRT MZF1 NFIB PDE4DIP MPI

4.09e-0619514392867_DN
DrugSp 1 (pharmaceutical)

HDAC5 NRF1 PPRC1 MED14 E4F1 NCOR1 JUND AP2A1 MZF1 BRD7 MMP2 ATP12A MED13 CDK6

9.62e-0654814314CID000099040
DrugEtoposide [33419-42-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A

DSCAM NRF1 MECOM NEB CDCA8 NCOR1 TOP2A INO80B

1.87e-0518014385027_DN
DrugCiclopirox ethanolamine [41621-49-2]; Down 200; 15uM; MCF7; HT_HG-U133A

ABHD6 MECOM CDCA8 NFIB NKX3-1 CDC25B TOP2A BORA

2.03e-0518214383317_DN
Drugalternariol monomethyl ether

GSTA1 GSTA2 TOP2A

2.82e-05101433ctd:C018206
DrugLY 294002; Down 200; 10uM; MCF7; HT_HG-U133A

MAP4 PPRC1 ABHD6 KLHL22 PLEKHM2 BRD4 BRPF1 AKAP10

3.09e-0519314381664_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

MAP4 STAT6 KLHL22 SRRT PLEKHM2 MZF1 ROBO1 NKX3-1

3.20e-0519414386958_DN
DrugColistin sulfate [1264-72-8]; Up 200; 3uM; HL60; HT_HG-U133A

MPP2 DSCAM ZC3H13 MFSD6 ADAMTS7 NKX3-1 INO80B NOVA2

3.45e-0519614382491_UP
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

MPP2 DSCAM MAP4 GON4L STAT6 NFIB INO80B BRWD1

3.57e-0519714386012_DN
DrugIopamidol [60166-93-0]; Down 200; 5.2uM; MCF7; HT_HG-U133A

ABHD6 STAT6 KLHL22 MZF1 PI4KB NMT2 NKX3-1 INO80B

3.57e-0519714383473_DN
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

FKBP15 KLHL22 SCYL2 JUND PLEKHM2 PI4KB AKAP10 INO80B

3.70e-0519814381479_DN
DrugNifurtimox [23256-30-6]; Down 200; 14uM; HL60; HT_HG-U133A

NRF1 TTLL7 JUND PRDM10 MRTFB MZF1 NMT2 PDE4DIP

3.84e-0519914382908_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; SKMEL5; HG-U133A

PPRC1 PIEZO1 MED14 RUSC1 GON4L CDCA8 STAT6 CCDC7

3.84e-051991438494_DN
DrugHydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A

PIGN HDAC5 NRF1 SRRT MAST4 PLEKHM2 MZF1 RERE

3.98e-0520014385494_UP
Diseasecortical surface area measurement

ZC3H13 NPAS3 MECOM LGALS12 MED13L PLXNB2 NHSL1 NCOR1 IGF2BP1 MTMR11 MAST4 ADAMTS7 NFIB ROBO1 MACF1 AKAP10 RERE FAM124B PRRC2A TNXB CDK6

1.08e-06134513721EFO_0010736
DiseaseGlioblastoma

SRRT NCOR1 BRD4 MMP2 CDK6

3.43e-05791375C0017636
DiseaseGiant Cell Glioblastoma

SRRT NCOR1 BRD4 MMP2 CDK6

4.61e-05841375C0334588
Diseasechemotherapy-induced alopecia

CACNB4 PCDH15

6.40e-0531372EFO_0005400
Diseasespontaneous preterm birth

MPP2 DSCAM NPAS3 NHSL1 INTS9

1.11e-041011375EFO_0006917
Diseaseacquired metabolic disease (implicated_via_orthology)

IGF2BP1 IGF2BP3

1.28e-0441372DOID:0060158 (implicated_via_orthology)
Diseaseneuroimaging measurement

MPP2 GATAD2A PLXNB2 NHSL1 NCOR1 IGF2BP1 MAST4 SNAP91 NFIB ROBO1 MACF1 AKAP10 RERE SLC4A9 CDK6

1.39e-04106913715EFO_0004346
DiseaseGlioblastoma Multiforme

SRRT NCOR1 BRD4 MMP2 CDK6

1.73e-041111375C1621958
DiseaseBladder Neoplasm

VWA3A NCOR1 KMT2C GLI1 MMP2

5.06e-041401375C0005695
DiseaseMalignant neoplasm of urinary bladder

VWA3A NCOR1 KMT2C GLI1 MMP2

5.23e-041411375C0005684
DiseaseProstatic Neoplasms

STARD10 DAG1 GSTA1 NCOR1 KMT2C BRD4 BRPF1 ROBO1 NKX3-1 TOP2A

6.26e-0461613710C0033578
DiseaseMalignant neoplasm of prostate

STARD10 DAG1 GSTA1 NCOR1 KMT2C BRD4 BRPF1 ROBO1 NKX3-1 TOP2A

6.26e-0461613710C0376358
Diseasealcohol consumption measurement

TOM1L2 PIGN TMEM161B MFSD6 NPAS3 LGALS12 JADE1 STAT6 IGF2BP1 MAST4 ZNF608 SNAP91 PLEKHM2 RERE MYO15A

6.75e-04124213715EFO_0007878
Diseasecortical thickness

TOM1L2 GATAD2A MECOM LGALS12 NHSL1 IGF2BP1 SH3PXD2B MAST4 SNAP91 ADAMTS7 ROBO1 MACF1 AKAP10 RERE

6.93e-04111313714EFO_0004840
DiseaseCancer of Nasopharynx

MECOM MMP2

7.54e-0491372C0238301
DiseaseNasopharyngeal Neoplasms

MECOM MMP2

7.54e-0491372C0027439
Diseaseprostate cancer (is_marker_for)

STAT6 KMT2C MMP2 CDC25B TOP2A

8.26e-041561375DOID:10283 (is_marker_for)
Diseaseaspartate aminotransferase measurement

PIEZO1 STARD10 HPSE2 ITIH1 TTLL7 GLI1 ROBO1 FKBP7 MYO15A PRRC2A MMUT CDK6

1.07e-0390413712EFO_0004736
Diseaseglioblastoma (is_marker_for)

BRD7 MMP2 CDK6

1.13e-03441373DOID:3068 (is_marker_for)
DiseaseIntellectual Disability

ZC3H14 GON4L MED13L KMT2C NFIB BRD4 MACF1 MED13

1.19e-034471378C3714756
DiseaseAbnormality of refraction

MPP2 DSCAM ABHD6 ZNF608 SNAP91 ROBO1 NKX2-2 RERE MMP2 CREB3L2

1.22e-0367313710HP_0000539
Diseaseschizophrenia, anorexia nervosa

MPP2 GATAD2A RERE

1.45e-03481373MONDO_0005090, MONDO_0005351
DiseaseMalignant neoplasm of breast

PCDHB15 MED14 MECOM TEK NME8 NCOR1 GLI1 ROBO1 MACF1 MMP2 REPS2 PRRC2A TOP2A

1.52e-03107413713C0006142
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

NFU1 IGF2BP1 MTMR11 NFIB MACF1 RERE PRRC2A

1.60e-033641377EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease1,3,7-trimethylurate measurement

GSTA1 GSTA2

2.16e-03151372EFO_0021172
Diseasefemoral neck bone mineral density

HDAC5 HPSE2 CRACD NFIB RERE

2.26e-031961375EFO_0007785
Diseasebone density

TOM1L2 PIGN HDAC5 MED13L NME8 RERE MYO15A

2.30e-033881377EFO_0003923
Diseasefocal segmental glomerulosclerosis

CCDC7 SCNN1G

2.46e-03161372EFO_0004236
Diseasepreeclampsia, parental genotype effect measurement

PIGN MECOM

2.46e-03161372EFO_0000668, EFO_0005939
Diseasemigraine without aura, susceptibility to, 4

MPP2 HPSE2

2.46e-03161372MONDO_0011847
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

NPAS3 ZKSCAN2 RTN1 SNAP91 RERE

2.47e-032001375EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
DiseaseLiver carcinoma

CDCA8 KMT2C IGF2BP1 IGF2BP3 GLI1 ROBO1 MMP2 TOP2A

2.61e-035071378C2239176
Diseasecognitive function measurement

DSCAM MAP4 PIEZO1 TMEM161B STARD10 PLXNB2 TTLL7 IGF2BP1 BBX MAST4 ZNF608 NFIB FHDC1 TNXB HYDIN

2.77e-03143413715EFO_0008354
Diseaseocular hypertension (biomarker_via_orthology)

GLI1 MMP2

2.78e-03171372DOID:9282 (biomarker_via_orthology)
Diseaseirritable bowel syndrome

TMEM161B PCDH15 RERE PRRC2A

3.31e-031311374EFO_0000555
Diseasecomparative body size at age 10, self-reported

GATAD2A BCL7C NPAS3 MED13L MTMR11 MAST4 RERE

3.56e-034201377EFO_0009819
Diseasediet measurement

MPP2 DSCAM NRF1 MFSD6 NPAS3 HPSE2 ZKSCAN2 SCYL2 ZNF608 ROBO1 AKAP10 RERE

3.64e-03104913712EFO_0008111
Diseasecoronary artery disease

DSCAM USP43 MECOM TEK NFU1 CRACD IGF2BP1 MAST4 ADAMTS7 NFIB NANOS3 CFAP161 TNXB

3.79e-03119413713EFO_0001645
Diseasenumber of teeth measurement

IGF2BP1 IGF2BP3

3.85e-03201372EFO_0010073
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

NCOR1 MMP2

4.24e-03211372DOID:11612 (biomarker_via_orthology)
Diseasegastric ulcer (biomarker_via_orthology)

TEK MMP2

4.24e-03211372DOID:10808 (biomarker_via_orthology)
DiseaseHbA1c measurement

PIEZO1 BCL7C DAG1 TNRC6C IGF2BP3 ADAMTS7 GAB3 MACF1 MYO15A

4.37e-036751379EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
AVEKIPLIPSTPEEM

ABHD6

196

Q9BV23
AESMPPAESVPLIGK

CHRNA10

286

Q9GZZ6
MEPSQSLPEKGPVTI

C2orf16

936

Q68DN1
MPEEERSIPEKGLEP

SLC4A9

941

Q96Q91
GETPEGIKAEPLTPM

BBX

566

Q8WY36
GIKAEPLTPMEDALP

BBX

571

Q8WY36
DKIEPMVLRSPPTGE

CCDC7

46

Q96M83
EMKPVDVGRPVIRPP

BRD4

1151

O60885
AKEMEITEVEPPGRL

BRD7

496

Q9NPI1
ISPDAAKPIPITEAM

AKAP10

306

O43572
EMPPFPERESSILAK

AP2A1

601

O95782
VEILLAMKPPGDVPE

CFAP46

1246

Q8IYW2
PEPLQRPEMLKEETR

CUEDC2

111

Q9H467
KVPEPGVPTETIKDM

CDK6

111

Q00534
PELDLFAMKPPETSV

SNAP91

491

O60641
LPKPPTEDTRAMEQA

CFAP161

281

Q6P656
VPSMRPVVLVGPSLK

CACNB4

216

O00305
PEMKVRDSSLEPGTP

ADAMTS7

1301

Q9UKP4
TVTPRDKPMGPLLVA

MMP2

496

P08253
PEPMLEPDQKRSLES

NANOS3

36

P60323
RPKTISIDENMEPSP

NFIB

271

O00712
GSPRKPPMDEKSLEE

GSTA1

201

P08263
ELADSLVPMEIKPGI

INTS9

521

Q9NV88
RSLPLKMEPQSPGEV

MECOM

716

Q03112
DMKSERRPPSPDVIV

GATAD2A

91

Q86YP4
SMRTDLPPVAKAPGI

FHDC1

1046

Q9C0D6
ESRPPKLVMESVTLP

KMT2C

681

Q8NEZ4
PAASIEMTLKNPERP

MED13L

1776

Q71F56
ETEMALGKDVTPPPE

MAP4

511

P27816
LPDVTKTSGLRPMEP

NMT2

331

O60551
PGKPVLETRTMDFPT

NFU1

76

Q9UMS0
KPSEDSPPLEMLGPR

ITIH1

626

P19827
SGSRKPPIPLMETAE

MTMR11

186

A4FU01
GMDPEKPGTPIVLRR

MYO15A

616

Q9UKN7
GAKELDIMSNTPPPR

GAB3

296

Q8WWW8
IAPPETPDSKVRMVI

IGF2BP1

441

Q9NZI8
TPDSKVRMVIITGPP

IGF2BP1

446

Q9NZI8
MIDPPRSTVPDAVTK

ATP12A

606

P54707
PPLSPIDMDTQERIK

JUND

256

P17535
RLEVSMVKPTPGLTP

CDCA8

176

Q53HL2
TETMAPPVRDPVPGK

DAG1

351

Q14118
GSPRKPPMDEKSLEE

GSTA2

201

P09210
KEETSRPPMPLITTE

NHSL1

1061

Q5SYE7
MDKEVPKGSPREPAL

ETDB

1

P0DPP9
VMITGKLDIPEPRRP

PLXNB2

1296

O15031
TVMSPGEKLDPIPDS

LGALS12

21

Q96DT0
EDEVSMKGRPPPTPL

FKBP15

1191

Q5T1M5
IKEEPSPISKMRPVT

MRTFB

916

Q9ULH7
PPLTIDGIPVSVDKM

NRF1

186

Q16656
LPEDGALMDKPVPLS

KDM4D

491

Q6B0I6
PPGMESLISAPLVKT

CDC25B

286

P30305
ESRLTVPEGAMKPQP

GLI1

426

P08151
PVPPDAVRMVGIRKT

MPP2

156

Q14168
PDMKIEEVPELTLPI

PRDM10

751

Q9NQV6
PEVPALEASAPLGKM

KIAA1191

6

Q96A73
PEFPEREMTLKIPET

PCDHB15

131

Q9Y5E8
PLVMVDDGTLPELKP

HPSE2

546

Q8WWQ2
DKTMLAERIPVPSSP

MFSD6

631

Q6ZSS7
MEPEAPDSRKRPLET

NOVA2

1

Q9UNW9
PVPDFTIMKTEVPGS

MPI

341

P34949
APDAKVRMVIITGPP

IGF2BP3

446

O00425
MPPLIPAEVDKIREC

MACF1

5916

Q9UPN3
LVAVPESLPEKMRPA

MFSD14A

206

Q96MC6
EGCPPPALTEEMLLK

INO80B

201

Q9C086
PPLPASDSKLVERAM

MED14

376

O60244
LEDGLPKMPCTVPET

PAQR8

26

Q8TEZ7
EDSLSRKPDPEPGRM

NDFIP2

81

Q9NV92
RPPPVSELATKGTMV

PCDH15

1041

Q96QU1
RGPTELLSPLVMPSE

BTBD18

566

B2RXH4
TDMCPGEKRKVVIPP

FKBP7

101

Q9Y680
LPPGMSVDPKESSVL

FAM124B

191

Q9H5Z6
PVKRPPLTMTDDLEH

HYDIN

2621

Q4G0P3
EPPKLLETVRFPLME

KLHL22

236

Q53GT1
PMLTKEEPVPELLEA

BCL7C

161

Q8WUZ0
MPILEQKLEPGTEPL

COL20A1

1221

Q9P218
ESKMQITPETPGRIP

BORA

6

Q6PGQ7
RKRPMLGPSEETAPQ

CRACD

746

Q6ZU35
PTPGDLEEIVKMEPE

GON4L

1316

Q3T8J9
VPEIMPKLPTDLAGV

CCP110

421

O43303
KMPPLVSPQDRTEEE

EDDM13

61

A0A1B0GTR0
GPMLDKEIPPSISRV

BRWD1

86

Q9NSI6
GAKEPMAEVTPPPVR

DRGX

101

A6NNA5
MGEKVSEAPEPVPRG

MAST4

1

O15021
TTDGRPRPPMEPKEI

FOXS1

181

O43638
MDKEVPKGSPREPAL

ETDA

1

Q3ZM63
ELSLGMKALAPEPPV

E4F1

341

Q66K89
TVEVKPVLPRAMPSS

HDAC5

31

Q9UQL6
PVTGPQAPTIKELMR

SCNN1G

16

P51170
PKKMPALVIPEVGSR

PPRC1

1306

Q5VV67
VTVLVERVMPPPKLD

CDH16

551

O75309
TPLEKEEPPLEMNTG

CREB3L2

151

Q70SY1
PLTIGKEVTMDVPAP

PLA2G4D

246

Q86XP0
SERSEPGLLIPEMKD

PLEKHM2

386

Q8IWE5
MSKIRGLPPEVREPG

GARIN1A

1

Q6NXP2
TLKRPTVLEPIPMEA

DSCAM

1936

O60469
SVLALVKRGAPPEMP

RUSC1

816

Q9BVN2
DSPPMKPSALDAIRE

RTN1

486

Q16799
GALEPETPMLPRKPE

RTN1

541

Q16799
LDSPEAEELPAMKRP

TAF3

181

Q5VWG9
EEPSPPSIRRKMEID

TNRC6C

711

Q9HCJ0
MEKLAASTEPQGPRP

STARD10

1

Q9Y365
MRAPIPEPKPGDLIE

PLAAT3

1

P53816
PPLGKESIPLMTEAT

TMEM161B

296

Q8NDZ6
MPEKRLTAEPPTITE

RGS22

1

Q8NE09
SKLSRGMPPLEIVPE

NCOR1

1411

O75376
LPPGLMEAKVRVLDP

PRSS57

171

Q6UWY2
MLRERGTPPVDPKLA

PRRC2A

776

P48634
TPTVRPDADQMTKIP

SCYL2

311

Q6P3W7
SKPDGPMVAVAEPVR

SLC26A10

451

Q8NG04
ARAEKGMEVTPLPSP

NKX2-2

186

O95096
MLRVPEPRPGEAKAE

NKX3-1

1

Q99801
PEIPMIGKLEPREDA

NAP1L3

446

Q99457
LRMEGPPPNTSVKVI

NPAS3

116

Q8IXF0
ERMKPGFEVKPPELD

RERE

1321

Q9P2R6
PDPLVPSKPMEDRID

MED13

566

Q9UHV7
IPEVSIGSPEKMEPI

JADE1

286

Q6IE81
PSSEIPMEKEPGEGR

PPP1R15B

386

Q5SWA1
MGDTVVEPAPLKPTS

PI4KB

1

Q9UBF8
SIAEIDLGVPPPVMK

SRRT

136

Q9BXP5
PVPPLEVLKLGEQMT

BRPF1

1121

P55201
VDVSPPKVEADMSLP

AHNAK2

2176

Q8IVF2
PRKFDLPLTVMPSVE

USP43

926

Q70EL4
SMPTTKPRPGLREEK

UBN2

791

Q6ZU65
MGPTDPEEAKLLSPD

NME8

536

Q8N427
SIEEAMKRGEDPPTP

REPS2

466

Q8NFH8
GPPVPAKDTETRERM

SRCIN1

556

Q9C0H9
RIIPKIMPEKPAEEG

SSX6P

106

Q7RTT6
ISDPDMEEKPSLPPR

SH3PXD2B

511

A1X283
IKMTVERDQPLPTPE

STAT6

646

P42226
PGLSKMEPQTPDISL

SERINC4

326

A6NH21
MTPEPPIKPRLGELT

TNXB

2621

P22105
LEVRPVVVPKLPSMD

ROBO1

1501

Q9Y6N7
PLPTNEEMTLVKPDG

TEK

376

Q02763
PLMPVVGRKPDISLV

PIGN

606

O95427
EPMLNGTEKTPPLIT

TOP2A

941

P11388
KPTIMGEPITVNPAL

ZNF608

791

Q9ULD9
RAPSTDKPKEMIPVP

ZKSCAN2

431

Q63HK3
MDLRPELPTTLGPVS

PIEZO1

486

Q92508
PEIMDLSELRPFSKP

TOGARAM1

1241

Q9Y4F4
ERAKAAEMVPDLPSP

TOM1L2

466

Q6ZVM7
MSTVKPLREPAPSED

ZC3H14

156

Q6PJT7
IPTRLPKMEVRAEEP

nan

66

A6NL46
RGPKPLCSMPESTEI

TTLL7

526

Q6ZT98
PTVPLGARMSIKDDP

VWA3A

756

A6NCI4
PRTPPITTKEELVEM

ZC3H13

1031

Q5T200
PTATEGPETKPVLMA

TRIM28

566

Q13263
MPTEIEFPESRKPIS

ZNF649

146

Q9BS31
FKLEPMETERSPGPR

ZNF263

156

O14978
RDTMDLPEELPGVKP

MMUT

76

P22033
LDTSPVMKTPPKLEG

PDE4DIP

2151

Q5VU43
RAPPEDEGPVMVKLE

MZF1

11

P28698
LGKGIPTPITPEMER

NEB

6251

P20929