| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | transmembrane transporter activity | TMCO1 TMC3 SERINC3 SLC38A3 ABCG2 SLC4A11 TMC1 SLC16A10 TMEM175 | 7.91e-07 | 1180 | 20 | 9 | GO:0022857 |
| GeneOntologyMolecularFunction | transporter activity | TMCO1 TMC3 SERINC3 SLC38A3 ABCG2 SLC4A11 TMC1 SLC16A10 TMEM175 | 1.66e-06 | 1289 | 20 | 9 | GO:0005215 |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | 8.51e-06 | 293 | 20 | 5 | GO:0008514 | |
| GeneOntologyMolecularFunction | L-amino acid transmembrane transporter activity | 4.70e-05 | 71 | 20 | 3 | GO:0015179 | |
| GeneOntologyMolecularFunction | carboxylic acid transmembrane transporter activity | 4.77e-05 | 207 | 20 | 4 | GO:0046943 | |
| GeneOntologyMolecularFunction | organic acid transmembrane transporter activity | 4.86e-05 | 208 | 20 | 4 | GO:0005342 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | 7.32e-05 | 459 | 20 | 5 | GO:0005216 | |
| GeneOntologyMolecularFunction | aromatic amino acid transmembrane transporter activity | 7.39e-05 | 13 | 20 | 2 | GO:0015173 | |
| GeneOntologyMolecularFunction | organic cation transmembrane transporter activity | 7.50e-05 | 83 | 20 | 3 | GO:0015101 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 7.78e-05 | 465 | 20 | 5 | GO:0046873 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 9.25e-05 | 793 | 20 | 6 | GO:0015075 | |
| GeneOntologyMolecularFunction | channel activity | 1.38e-04 | 525 | 20 | 5 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 1.39e-04 | 526 | 20 | 5 | GO:0022803 | |
| GeneOntologyMolecularFunction | mechanosensitive monoatomic ion channel activity | 1.44e-04 | 18 | 20 | 2 | GO:0008381 | |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 1.51e-04 | 105 | 20 | 3 | GO:0015171 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 3.15e-04 | 627 | 20 | 5 | GO:0022890 | |
| GeneOntologyMolecularFunction | proton channel activity | 3.30e-04 | 27 | 20 | 2 | GO:0015252 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 3.33e-04 | 343 | 20 | 4 | GO:0005261 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 4.10e-04 | 664 | 20 | 5 | GO:0008324 | |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 7.50e-04 | 758 | 20 | 5 | GO:0015318 | |
| GeneOntologyMolecularFunction | amide transmembrane transporter activity | 8.01e-04 | 42 | 20 | 2 | GO:0042887 | |
| GeneOntologyMolecularFunction | proton transmembrane transporter activity | 8.32e-04 | 188 | 20 | 3 | GO:0015078 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 1.15e-03 | 477 | 20 | 4 | GO:0022804 | |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | 3.05e-03 | 296 | 20 | 3 | GO:0015291 | |
| GeneOntologyMolecularFunction | monocarboxylic acid transmembrane transporter activity | 3.62e-03 | 90 | 20 | 2 | GO:0008028 | |
| GeneOntologyMolecularFunction | calcium channel activity | 7.29e-03 | 129 | 20 | 2 | GO:0005262 | |
| GeneOntologyMolecularFunction | G protein-coupled peptide receptor activity | 7.73e-03 | 133 | 20 | 2 | GO:0008528 | |
| GeneOntologyMolecularFunction | antiporter activity | 8.30e-03 | 138 | 20 | 2 | GO:0015297 | |
| GeneOntologyMolecularFunction | peptide receptor activity | 8.54e-03 | 140 | 20 | 2 | GO:0001653 | |
| GeneOntologyMolecularFunction | symporter activity | 9.75e-03 | 150 | 20 | 2 | GO:0015293 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 9.87e-03 | 151 | 20 | 2 | GO:0015085 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 1.05e-02 | 884 | 20 | 4 | GO:0004930 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 1.25e-02 | 171 | 20 | 2 | GO:0015081 | |
| GeneOntologyBiologicalProcess | organic anion transport | 6.77e-06 | 515 | 20 | 6 | GO:0015711 | |
| GeneOntologyBiologicalProcess | carboxylic acid transport | 3.67e-05 | 410 | 20 | 5 | GO:0046942 | |
| GeneOntologyBiologicalProcess | organic acid transport | 3.76e-05 | 412 | 20 | 5 | GO:0015849 | |
| GeneOntologyBiologicalProcess | aromatic amino acid transport | 6.92e-05 | 13 | 20 | 2 | GO:0015801 | |
| GeneOntologyBiologicalProcess | transport across blood-brain barrier | 7.85e-05 | 87 | 20 | 3 | GO:0150104 | |
| GeneOntologyBiologicalProcess | vascular transport | 8.12e-05 | 88 | 20 | 3 | GO:0010232 | |
| GeneOntologyBiologicalProcess | L-amino acid transport | 1.49e-04 | 108 | 20 | 3 | GO:0015807 | |
| GeneOntologyBiologicalProcess | organic cation transport | 3.55e-04 | 145 | 20 | 3 | GO:0015695 | |
| GeneOntologyBiologicalProcess | amide transport | 6.34e-04 | 420 | 20 | 4 | GO:0042886 | |
| GeneOntologyBiologicalProcess | amino acid transport | 8.42e-04 | 195 | 20 | 3 | GO:0006865 | |
| GeneOntologyBiologicalProcess | monocarboxylic acid transport | 1.09e-03 | 213 | 20 | 3 | GO:0015718 | |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | 1.18e-03 | 866 | 20 | 5 | GO:0055082 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | 1.49e-03 | 1374 | 20 | 6 | GO:0006811 | |
| GeneOntologyBiologicalProcess | neutral amino acid transport | 1.53e-03 | 60 | 20 | 2 | GO:0015804 | |
| GeneOntologyBiologicalProcess | positive regulation of organic acid transport | 1.68e-03 | 63 | 20 | 2 | GO:0032892 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | 2.05e-03 | 981 | 20 | 5 | GO:0019725 | |
| GeneOntologyBiologicalProcess | cellular response to osmotic stress | 2.19e-03 | 72 | 20 | 2 | GO:0071470 | |
| GeneOntologyBiologicalProcess | metal ion transport | 2.23e-03 | 1000 | 20 | 5 | GO:0030001 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | 2.53e-03 | 611 | 20 | 4 | GO:0030003 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | 2.70e-03 | 622 | 20 | 4 | GO:0006873 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | 3.59e-03 | 1115 | 20 | 5 | GO:0034220 | |
| GeneOntologyBiologicalProcess | regulation of intracellular pH | 3.70e-03 | 94 | 20 | 2 | GO:0051453 | |
| GeneOntologyBiologicalProcess | monoatomic cation transport | 4.21e-03 | 1157 | 20 | 5 | GO:0006812 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | 4.24e-03 | 705 | 20 | 4 | GO:0055080 | |
| GeneOntologyBiologicalProcess | vascular process in circulatory system | 4.25e-03 | 344 | 20 | 3 | GO:0003018 | |
| GeneOntologyBiologicalProcess | regulation of cellular pH | 4.26e-03 | 101 | 20 | 2 | GO:0030641 | |
| GeneOntologyBiologicalProcess | regulation of organic acid transport | 4.42e-03 | 103 | 20 | 2 | GO:0032890 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | 4.50e-03 | 717 | 20 | 4 | GO:0050801 | |
| GeneOntologyBiologicalProcess | response to osmotic stress | 5.30e-03 | 113 | 20 | 2 | GO:0006970 | |
| GeneOntologyBiologicalProcess | chemical homeostasis | 5.83e-03 | 1249 | 20 | 5 | GO:0048878 | |
| GeneOntologyBiologicalProcess | amino acid transmembrane transport | 5.96e-03 | 120 | 20 | 2 | GO:0003333 | |
| GeneOntologyBiologicalProcess | regulation of pH | 5.96e-03 | 120 | 20 | 2 | GO:0006885 | |
| GeneOntologyCellularComponent | basal part of cell | 2.33e-05 | 378 | 20 | 5 | GO:0045178 | |
| GeneOntologyCellularComponent | basolateral plasma membrane | 2.15e-04 | 320 | 20 | 4 | GO:0016323 | |
| GeneOntologyCellularComponent | basal plasma membrane | 3.16e-04 | 354 | 20 | 4 | GO:0009925 | |
| Domain | TMC | 2.74e-05 | 8 | 19 | 2 | IPR012496 | |
| Domain | TMC | 2.74e-05 | 8 | 19 | 2 | PF07810 | |
| Domain | GPCR_Rhodpsn_7TM | 4.14e-03 | 670 | 19 | 4 | IPR017452 | |
| Domain | 7tm_1 | 4.29e-03 | 677 | 19 | 4 | PF00001 | |
| Domain | G_PROTEIN_RECEP_F1_1 | 4.48e-03 | 685 | 19 | 4 | PS00237 | |
| Domain | G_PROTEIN_RECEP_F1_2 | 4.62e-03 | 691 | 19 | 4 | PS50262 | |
| Domain | GPCR_Rhodpsn | 4.64e-03 | 692 | 19 | 4 | IPR000276 | |
| Pathway | WP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS | 9.60e-05 | 93 | 14 | 3 | M39791 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 4.47e-04 | 32 | 14 | 2 | MM14957 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 4.75e-04 | 33 | 14 | 2 | M188 | |
| Pathway | WP_PROXIMAL_TUBULE_TRANSPORT | 1.42e-03 | 57 | 14 | 2 | M39812 | |
| Pathway | WP_GPCRS_PEPTIDE | 2.13e-03 | 70 | 14 | 2 | MM15959 | |
| Pathway | KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | 2.21e-03 | 272 | 14 | 3 | M13380 | |
| Pathway | WP_PEPTIDE_GPCRS | 2.44e-03 | 75 | 14 | 2 | M39696 | |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 3.82e-03 | 330 | 14 | 3 | M18334 | |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 3.92e-03 | 333 | 14 | 3 | MM14963 | |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 4.98e-03 | 108 | 14 | 2 | M823 | |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 5.07e-03 | 109 | 14 | 2 | MM15074 | |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | 7.98e-03 | 430 | 14 | 3 | MM15160 | |
| Pathway | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | 8.58e-03 | 143 | 14 | 2 | MM15055 | |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | 9.78e-03 | 463 | 14 | 3 | M507 | |
| Pathway | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | 1.03e-02 | 157 | 14 | 2 | M4904 | |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 1.42e-02 | 186 | 14 | 2 | MM15994 | |
| Pathway | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 1.58e-02 | 197 | 14 | 2 | MM14970 | |
| Pathway | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 1.58e-02 | 197 | 14 | 2 | M12289 | |
| Pubmed | 9.42e-07 | 3 | 20 | 2 | 24981230 | ||
| Pubmed | 8.78e-06 | 8 | 20 | 2 | 12812529 | ||
| Pubmed | 8.78e-06 | 8 | 20 | 2 | 12906855 | ||
| Pubmed | 1.16e-05 | 952 | 20 | 6 | 38569033 | ||
| Pubmed | 2.94e-05 | 105 | 20 | 3 | 30280653 | ||
| Pubmed | Amino acid transport across mammalian intestinal and renal epithelia. | 1.45e-04 | 31 | 20 | 2 | 18195088 | |
| Pubmed | 2.36e-04 | 212 | 20 | 3 | 19521566 | ||
| Pubmed | Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland. | 2.80e-04 | 43 | 20 | 2 | 34737342 | |
| Pubmed | 2.93e-04 | 44 | 20 | 2 | 23070814 | ||
| Pubmed | 4.09e-04 | 52 | 20 | 2 | 26590417 | ||
| GeneFamily | Transmembrane channel likes | 2.05e-05 | 8 | 16 | 2 | 1135 | |
| GeneFamily | Actins|Deafness associated genes | 4.39e-03 | 113 | 16 | 2 | 1152 | |
| GeneFamily | Solute carriers | 4.69e-03 | 395 | 16 | 3 | 752 | |
| ToppCell | droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.27e-05 | 165 | 20 | 3 | 622aca1d49bd8c917b131e4f4959d9dba411d22b | |
| ToppCell | TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9 | 5.56e-05 | 168 | 20 | 3 | 5ce3129a023a48a3d7e6b9306c1fc5addfef9675 | |
| ToppCell | facs-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.72e-05 | 179 | 20 | 3 | bbfbfb32773346080127055b5aafa36bbf7d0942 | |
| ToppCell | 10x5'-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue | 6.94e-05 | 181 | 20 | 3 | d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa | |
| ToppCell | facs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.06e-05 | 182 | 20 | 3 | 398ce074a04f6482470b488f1affae4af7d2ec58 | |
| ToppCell | facs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.65e-05 | 187 | 20 | 3 | df0279b7e94e26f5541b0e2a0ce56befa96ec8ca | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 9.33e-05 | 200 | 20 | 3 | 5f1de1f9305e1784c12d526f6c8bdd7d56229f9b | |
| Drug | L-368,899 | 4.01e-05 | 11 | 20 | 2 | CID000132857 | |
| Drug | PCB 180 | 4.81e-05 | 12 | 20 | 2 | CID000037036 | |
| Drug | estradiol 3-benzoate | 6.27e-05 | 89 | 20 | 3 | ctd:C074283 | |
| Drug | GHRP-6 | 7.86e-05 | 96 | 20 | 3 | CID004345065 | |
| Drug | ketene | 9.89e-05 | 17 | 20 | 2 | CID000010038 | |
| Drug | cyanyl | 1.38e-04 | 20 | 20 | 2 | CID005359238 | |
| Drug | TMCs | 2.00e-04 | 24 | 20 | 2 | CID000006397 | |
| Drug | A-26 | 2.17e-04 | 25 | 20 | 2 | CID000037120 | |
| Drug | corticosterone | 3.02e-04 | 381 | 20 | 4 | CID000005753 | |
| Drug | AC1L1CA3 | 3.36e-04 | 31 | 20 | 2 | CID000001806 | |
| Drug | C13:0 | 4.04e-04 | 34 | 20 | 2 | CID000012530 | |
| Drug | isoproturon | 4.04e-04 | 34 | 20 | 2 | CID000036679 | |
| Drug | R PD | 4.29e-04 | 35 | 20 | 2 | CID000448088 | |
| Drug | ditercalinium | 4.79e-04 | 37 | 20 | 2 | CID000003119 | |
| Drug | tricarbon | 5.33e-04 | 39 | 20 | 2 | CID006432003 | |
| Drug | diketopiperazine | 5.33e-04 | 39 | 20 | 2 | CID000007817 | |
| Drug | prazosin | 6.15e-04 | 193 | 20 | 3 | CID000004893 | |
| Drug | Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HG-U133A | 6.72e-04 | 199 | 20 | 3 | 1889_UP | |
| Drug | 1-aminoanthracene | 6.78e-04 | 44 | 20 | 2 | CID000011885 | |
| Drug | methyl ether | 7.09e-04 | 45 | 20 | 2 | CID000008254 | |
| Drug | permanganate | 7.41e-04 | 46 | 20 | 2 | CID000024401 | |
| Drug | di-fluoro | 8.07e-04 | 48 | 20 | 2 | CID000069610 | |
| Drug | tetrabromobisphenol A | 8.61e-04 | 891 | 20 | 5 | ctd:C020806 | |
| Drug | AC1L1X7A | 1.02e-03 | 54 | 20 | 2 | CID000011366 | |
| Drug | AC1L9LQQ | 1.14e-03 | 57 | 20 | 2 | CID000448224 | |
| Drug | icariin | 1.14e-03 | 57 | 20 | 2 | CID005318997 | |
| Drug | PCB 153 | 1.18e-03 | 58 | 20 | 2 | CID000037034 | |
| Drug | Russian VX | 1.34e-03 | 62 | 20 | 2 | CID000178033 | |
| Drug | 1XS7 | 1.48e-03 | 65 | 20 | 2 | CID000449218 | |
| Drug | acetonitrile | 1.57e-03 | 67 | 20 | 2 | CID000006342 | |
| Drug | DB02841 | 1.61e-03 | 68 | 20 | 2 | CID005288987 | |
| Drug | dehydroepiandrosterone sulfate | 1.74e-03 | 277 | 20 | 3 | CID000005244 | |
| Disease | urate measurement | 2.69e-04 | 895 | 20 | 5 | EFO_0004531 | |
| Disease | cups of coffee per day measurement | 3.35e-04 | 40 | 20 | 2 | EFO_0006782 | |
| Disease | coffee consumption measurement, tea consumption measurement | 4.06e-04 | 44 | 20 | 2 | EFO_0006781, EFO_0010091 | |
| Disease | Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive | 5.46e-04 | 51 | 20 | 2 | cv:CN043650 | |
| Disease | uric acid measurement | 6.73e-04 | 610 | 20 | 4 | EFO_0004761 | |
| Disease | Nonsyndromic genetic hearing loss | 1.21e-03 | 76 | 20 | 2 | cv:C5680182 | |
| Disease | Nonsyndromic Deafness | 1.37e-03 | 81 | 20 | 2 | C3711374 | |
| Disease | hearing impairment | 2.00e-03 | 98 | 20 | 2 | C1384666 | |
| Disease | triglyceride measurement, alcohol drinking | 2.04e-03 | 99 | 20 | 2 | EFO_0004329, EFO_0004530 | |
| Disease | triglyceride measurement, alcohol consumption measurement | 2.12e-03 | 101 | 20 | 2 | EFO_0004530, EFO_0007878 | |
| Disease | chronic lymphocytic leukemia | 2.92e-03 | 119 | 20 | 2 | EFO_0000095 | |
| Disease | tea consumption measurement | 3.42e-03 | 129 | 20 | 2 | EFO_0010091 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| RMMLAFLVLSTGMFC | 171 | Q9H6U8 | |
| MTICFVFMMIFSGLL | 541 | Q9UNQ0 | |
| AMGSTECFLLGMMAF | 106 | Q8NGS5 | |
| IMNSFLTMESCTFMI | 106 | P0C7T3 | |
| SFFSLLSVLCVMLSM | 96 | P81408 | |
| CLITMFFTMLALMAS | 196 | P32245 | |
| MAQTSSYFMLISCLM | 1 | P05451 | |
| LLCAFGMSSLPYMKM | 826 | Q8NBS3 | |
| LAMLLFMLFLCMLPT | 621 | Q7Z5M5 | |
| ALCFAMLGFLLMTMS | 471 | Q99624 | |
| SMFAIGFCFTALMGM | 141 | Q9UM00 | |
| NVFFSPMSMSCALAM | 26 | P35237 | |
| MVMSLLGMFCPTLFD | 411 | Q8TDI8 | |
| SFLAFMMAILGMKCT | 91 | P56748 | |
| LSMFASTYMLLAMTL | 116 | P47901 | |
| CMMTITFLPYTFSLM | 116 | Q9BSA9 | |
| GALMTTACFLFMFMG | 376 | Q92544 | |
| MLCLASLYIMMTLTS | 411 | Q13530 | |
| MTALFLMSMLFGLTC | 1 | P01222 | |
| GSLCSFSLLMLIAMS | 61 | A6NGA9 | |
| FFFIGLMSMMIPLCS | 366 | Q8TF71 |