Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear periphery

MAPT HNRNPM HLTF HLCS DNTT

5.99e-05171515GO:0034399
GeneOntologyCellularComponentnuclear matrix

HNRNPM HLTF HLCS DNTT

3.77e-04140514GO:0016363
GeneOntologyCellularComponentfibrillar collagen trimer

COL11A1 COL5A3

3.79e-0412512GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL11A1 COL5A3

3.79e-0412512GO:0098643
HumanPhenoLagophthalmos

KMT2D ECEL1 DNMT3B

2.39e-0519163HP:0030001
DomainDUF1981

ARFGEF3 ARFGEF2

4.55e-054522PF09324
DomainDCB_dom

ARFGEF3 ARFGEF2

4.55e-054522IPR032629
DomainDCB

ARFGEF3 ARFGEF2

4.55e-054522PF16213
DomainSec7_C

ARFGEF3 ARFGEF2

4.55e-054522IPR015403
DomainBAH

TNRC18 BAHCC1

4.11e-0411522SM00439
DomainFib_collagen_C

COL11A1 COL5A3

4.11e-0411522IPR000885
DomainBAH

TNRC18 BAHCC1

4.11e-0411522PF01426
DomainCOLFI

COL11A1 COL5A3

4.11e-0411522PF01410
DomainBAH

TNRC18 BAHCC1

4.11e-0411522PS51038
DomainNC1_FIB

COL11A1 COL5A3

4.11e-0411522PS51461
DomainFib_collagen_C

COL11A1 COL5A3

4.11e-0411522PD002078
DomainBAH_dom

TNRC18 BAHCC1

4.11e-0411522IPR001025
DomainCOLFI

COL11A1 COL5A3

4.11e-0411522SM00038
DomainSec7

ARFGEF3 ARFGEF2

8.90e-0416522SM00222
DomainSEC7

ARFGEF3 ARFGEF2

8.90e-0416522PS50190
DomainSec7_dom

ARFGEF3 ARFGEF2

8.90e-0416522IPR000904
DomainPWWP

ZCWPW2 DNMT3B

1.85e-0323522PF00855
DomainTSPN

COL11A1 COL5A3

1.85e-0323522SM00210
DomainPWWP_dom

ZCWPW2 DNMT3B

1.85e-0323522IPR000313
DomainPWWP

ZCWPW2 DNMT3B

2.02e-0324522PS50812
DomainARM-type_fold

ARFGEF3 DOHH APC ARFGEF2 BTAF1

2.47e-03339525IPR016024
Domain-

DOHH APC ARFGEF2 BTAF1

3.37e-032225241.25.10.10
DomainSNF2_N

HLTF BTAF1

3.57e-0332522IPR000330
DomainSNF2_N

HLTF BTAF1

3.57e-0332522PF00176
DomainLaminin_G_2

COL11A1 COL5A3

5.54e-0340522PF02210
DomainLamG

COL11A1 COL5A3

6.67e-0344522SM00282
DomainARM-like

DOHH APC ARFGEF2 BTAF1

6.71e-03270524IPR011989
DomainZnf_FYVE_PHD

KMT2D ZBTB4 DNMT3B

7.97e-03147523IPR011011
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF3 MDN1 ARFGEF2 EPB41L5 BTAF1

5.04e-0710452531240132
Pubmed

Suppression of intestinal neoplasia by deletion of Dnmt3b.

APC DNMT3B

2.19e-06252216581773
Pubmed

NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein.

BTAF1 DRAP1

6.57e-06352215509807
Pubmed

Genotype-ocular biometry correlation analysis of eight primary angle closure glaucoma susceptibility loci in a cohort from Northern China.

COL11A1 GLIS3

6.57e-06352230399154
Pubmed

Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D.

KMT2D APC

6.57e-06352232024448
Pubmed

Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.

APC DNMT3B

6.57e-06352224837369
Pubmed

Hsp90 activator Aha1 drives production of pathological tau aggregates.

MAPT AHSA1

6.57e-06352228827321
Pubmed

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons.

MAPT DNMT3B

6.57e-06352230644360
Pubmed

Loss of HLTF function promotes intestinal carcinogenesis.

HLTF APC

1.31e-05452222452792
Pubmed

Identification of brain-to-spinal circuits controlling the laterality and duration of mechanical allodynia in mice.

MAPT PDYN

1.31e-05452236952340
Pubmed

Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease.

PDYN CHGB

1.31e-05452219131325
Pubmed

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

APC DNMT3B

1.31e-05452218056424
Pubmed

Introduction of cytogenetic tests in colorectal cancer screening.

COL11A1 APC

2.19e-05552219337631
Pubmed

Experience-dependent myelination following stress is mediated by the neuropeptide dynorphin.

MAPT PDYN

2.19e-05552234536353
Pubmed

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

MAPT AHSA1

2.19e-05552220071522
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

LPIN3 KMT2D MDN1 HNRNPM SNRNP70

2.65e-0523452536243803
Pubmed

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ.

PDYN KIF18B SNX19

3.00e-054052327197753
Pubmed

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.

MAPT AHSA1

3.28e-05652230382094
Pubmed

The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.

COL11A1 COL5A3

3.28e-05652210722718
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LPIN3 TNRC18 KMT2D MDN1 ZBTB4 ARFGEF2 BTAF1 ZZEF1 BAHCC1

3.44e-05110552935748872
Pubmed

Timing Mechanisms Underlying Gate Control by Feedforward Inhibition.

MAPT PDYN

4.58e-05752230122375
Pubmed

Identification of spinal circuits transmitting and gating mechanical pain.

MAPT PDYN

4.58e-05752225467445
Pubmed

The distribution and characterization of endogenous protein arginine N-methyltransferase 8 in mouse CNS.

MAPT APC

4.58e-05752219576965
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

LPIN3 HLTF APC PIP5K1A BTAF1 ZZEF1 RGS3

4.97e-0565052738777146
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

MDN1 CASP14 HNRNPM BTAF1 RGS3

5.43e-0527252531010829
Pubmed

The pro-alpha2(XI) collagen gene is expressed in odontoblasts.

COL11A1 COL5A3

6.10e-05852220059976
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

CASP14 DNAJA4 HNRNPM PIP5K1A BTAF1 SNRNP70 AHSA1 PRPF18

9.09e-0597152833306668
Pubmed

The mahogany protein is a receptor involved in suppression of obesity.

PDYN CHGB

9.79e-051052210086355
Pubmed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.

AHRR BBS7 ZBTB4 ZZEF1

1.27e-0417152428700664
Pubmed

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.

KMT2D APC

1.69e-041352216510874
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

BBS7 CHGB SNRNP70 RGS3

1.94e-0419152420195357
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

PDYN MON1B

1.97e-041452224811271
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

DNAJA4 MAP3K14 HNRNPM PIP5K1A AHSA1

2.09e-0436352525036637
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MDN1 HNRNPM HLTF ARFGEF2 BTAF1 SNRNP70

2.27e-0458252620467437
Pubmed

Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.

MAPT PDYN

2.27e-041552218400903
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

KMT2D APC

2.27e-041552216510875
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

MDN1 ZBTB4 HNRNPM

2.30e-047952326446488
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ARFGEF3 TNRC18 MAPT BCKDK HNRNPM SANBR APC SNRNP70

2.70e-04113952836417873
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LPIN3 ARFGEF3 MDN1 MAPT MAP3K14 APC EPB41L5

2.82e-0486152736931259
Pubmed

Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.

SLC18A1 CHGB

2.94e-041752210357937
Pubmed

Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.

MAPT APC

4.09e-042052225535916
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

CASP14 HNRNPM DACH1 AHSA1 PRPF18

5.26e-0444452534795231
Pubmed

Role of β-catenin in development of bile ducts.

GLIS3 APC

5.44e-042352226856660
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

TNRC18 KMT2D

5.44e-04235229225980
Pubmed

Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.

CASP14 HNRNPM NCCRP1

5.61e-0410752332989256
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

TNRC18 HNRNPM BAHCC1

6.08e-0411052326841866
Pubmed

Rheb1 is required for mTORC1 and myelination in postnatal brain development.

MAPT APC

6.43e-042552221238928
Pubmed

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

HNRNPM SNRNP70

6.43e-04255229731529
Pubmed

Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development.

ECEL1 DNMT3B

6.96e-042652227122033
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AHRR TNRC18 ZBTB4 EPB41L5 MON1B

8.42e-0449352515368895
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

CASP14 HNRNPM AHSA1

9.65e-0412952328973437
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KMT2D MDN1 MAPT ARFGEF2 BTAF1 ZFX

1.02e-0377452615302935
Pubmed

The DNA sequence and comparative analysis of human chromosome 20.

LPIN3 PDYN ARFGEF2 CHGB DNMT3B

1.04e-0351752511780052
Pubmed

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

MAPT BCKDK

1.12e-033352225064009
Pubmed

Discovery and validation of genes driving drug-intake and related behavioral traits in mice.

DNAJA4 ZBTB4

1.12e-033352238164795
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TNRC18 KMT2D DACH1 HLTF SNRNP70 AHSA1 PRPF18

1.22e-03110352734189442
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

ARFGEF3 MDN1 BCKDK MAP3K14 HLTF BTAF1 SNRNP70 SNX19

1.26e-03144052830833792
GeneFamilyPWWP domain containing

ZCWPW2 DNMT3B

9.17e-04223721147
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC18 KMT2D

1.19e-0325372775
GeneFamilyCollagens

COL11A1 COL5A3

3.99e-0346372490
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARFGEF3 MAPT APC

5.97e-03181373694
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 CDH20 MAPT PDYN CHGB

2.80e-0618653524b23880d4ff8fb4a23e2012d5890b9e2fcf7283
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

ARFGEF3 MAPT SLC18A1 GRIK5 CHGB

3.43e-06194535b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

ARFGEF3 MAPT SLC18A1 GRIK5 CHGB

3.43e-061945351e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor|bone_marrow / Manually curated celltypes from each tissue

GRIK5 DNMT3B BAHCC1 DNTT

2.98e-05149534078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 GLIS3 CHGB

3.48e-05155534498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

DACH1 DNMT3B BAHCC1 DNTT

4.44e-051655347b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

GRIK5 DNMT3B BAHCC1 DNTT

4.65e-05167534cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 PDYN CHGB

4.76e-051685344e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 PDYN CHGB

4.76e-0516853438ba7737ae0afffcbd3aa499403e83c24a922127
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

DACH1 KIF18B BAHCC1 DNTT

5.46e-05174534029394e107bf7ad58056d2216070aa2e964fff12
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPIN3 MAPT HLCS BTAF1

5.71e-051765348e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

MDN1 CDH20 MAPT ZBTB4

5.83e-05177534e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 GLIS3 CHGB

6.09e-05179534d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 GLIS3 CHGB

6.09e-051795348ce5000088b727783a0619baa16a2cd036d21f54
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SLC18A1 GLIS3 CHGB

6.36e-051815342392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAPT ECEL1 GRIK5 CHGB

6.92e-05185534110d5f02759c8235b14aea524ea47199696094ea
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AHRR CDH20 MAPT COL5A3

6.92e-05185534a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

ARFGEF3 ZCWPW2 GLIS3 EPB41L5

7.07e-051865349798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

ARFGEF3 ZCWPW2 GLIS3 EPB41L5

7.07e-051865343006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

ARFGEF3 ZCWPW2 GLIS3 EPB41L5

7.52e-05189534f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MAPT SLC18A1 ECEL1 CHGB

7.83e-051915343a5081dc542ac6262acfe5f8084a86616fee8082
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZCWPW2 HLCS MON1B ZZEF1

7.83e-05191534cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AHRR SLC18A1 SLC24A1

7.99e-05705331d06fd0e20f4b3ea71a83c87736236f5c8d39f65
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AHRR SLC18A1 SLC24A1

7.99e-0570533e446f52534a1e8291dbb0973c6bc5094a3ebc96b
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

ARFGEF3 ZCWPW2 GLIS3 EPB41L5

7.99e-05192534d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAJA4 MAP3K14 BTAF1 AHSA1

8.15e-05193534dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GLIS3 SLC25A37 NCCRP1

8.32e-05194534855d6acfcf323868ba98b213f06186ad4793d4ed
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GLIS3 SLC25A37 NCCRP1

8.32e-05194534ca051088f880154ae2fd3f0ab3cef5a8dba8c371
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GLIS3 SLC25A37 NCCRP1

8.32e-05194534dc531cf9089f2c956621d70d49a2b8219b4b45c1
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GLIS3 SLC25A37 NCCRP1

8.32e-0519453429a7770bdbea6081a9ed64a997cd92a1cbf4af58
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 MAPT PDYN CHGB

8.83e-05197534b9478212f14b7888e3abac02995177974ac3bd17
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

COL11A1 GLIS3 DACH1 COL5A3

8.83e-051975349d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

COL11A1 GLIS3 DACH1 COL5A3

8.83e-0519753461749ccafeb938c310cff1de5ff924a1c794325a
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 MAPT PDYN CHGB

9.00e-0519853485881637641d8996be2edc65c4bceff0433135e7
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early|World / Primary Cells by Cluster

HNRNPM DACH1 ECEL1 RGS3

9.18e-05199534549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early-40|World / Primary Cells by Cluster

HNRNPM DACH1 ECEL1 RGS3

9.18e-0519953423625d757173bdd35a51c7919ff4b588168d2553
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron|5w / Sample Type, Dataset, Time_group, and Cell type.

MAPT APC ECEL1 CHGB

9.36e-05200534c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCelldroplet-Fat-Scat-18m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 COL11A1 SLC25A37

1.23e-04815339a1cc6da6b7e697159a857c0dfe6e2a494160f9c
ToppCelldroplet-Fat-Scat-18m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 COL11A1 SLC25A37

1.23e-048153340981efef1b79adaa08fd20cf87955d0ae973ca7
ToppCelldroplet-Fat-Scat-18m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 COL11A1 SLC25A37

1.23e-048153398ee7f5a66dc29c9563cabea8160f118bcbbde73
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A

MAPT DNAJA4 APC EPB41L5 HLCS GRIK5 SLC24A1

2.73e-071935273810_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

DOHH DNAJA4 DACH1 APC EPB41L5 HLCS SLC24A1

2.83e-071945273606_DN
DrugBicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A

DNAJA4 ITGA10 APC GRIK5 SLC24A1 BAHCC1

5.36e-061955262796_UP
DrugHeliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A

MAPT BBS7 APC HLCS SLC24A1 RGS3

5.52e-061965264739_UP
Drugbeta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A

DNAJA4 MAP3K14 ITGA10 GRIK5 SLC25A37 ZFX

5.52e-061965264984_DN
DrugSulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; PC3; HT_HG-U133A

MAPT DNAJA4 GRIK5 SLC24A1 SLC25A37 ZFX

5.68e-061975265843_UP
Drugaspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A

DNAJA4 ITGA10 APC GRIK5 SLC24A1 BAHCC1

6.02e-061995265201_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

DACH1 CHGB ZZEF1 AHSA1 SLC25A37

7.82e-051935256938_UP
DrugGlimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A

MAPT DNAJA4 ITGA10 HLCS GRIK5

7.82e-051935254973_DN
DrugBromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A

DOHH MAPT DNAJA4 APC HLCS

8.21e-051955253719_DN
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

ITGA10 HLCS GRIK5 ZFX BAHCC1

8.21e-051955254980_DN
DrugPiromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A

APC EPB41L5 SLC25A37 ZFX BAHCC1

8.21e-051955254398_DN
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A

DOHH MAPT DNAJA4 HLCS SLC24A1

8.41e-051965254151_DN
DrugMethoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A

ITGA10 HLCS GRIK5 ZFX BAHCC1

8.41e-051965254972_DN
DrugAmrinone [60719-84-8]; Up 200; 21.4uM; HL60; HT_HG-U133A

DNAJA4 APC EPB41L5 HLCS RGS3

8.41e-051965252724_UP
DrugPromethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

DOHH MAPT DACH1 SLC25A37 BAHCC1

8.61e-051975255317_UP
DrugAjmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ITGA10 GRIK5 SLC24A1 RGS3 ZFX

8.61e-051975255459_DN
DrugProbenecid [57-66-9]; Down 200; 14uM; MCF7; HT_HG-U133A

MDN1 MAPT ARFGEF2 SLC25A37 ZFX

8.61e-051975254771_DN
DrugNorfloxacin [70458-96-7]; Up 200; 12.6uM; PC3; HT_HG-U133A

MAPT APC HLCS ZZEF1 RGS3

8.61e-051975257283_UP
DrugDenatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A

BBS7 APC GRIK5 SLC25A37 ZFX

8.82e-051985256502_DN
DrugRepaglinide [135062-02-1]; Up 200; 8.8uM; PC3; HT_HG-U133A

SLC18A1 DNAJA4 APC RGS3 BAHCC1

8.82e-051985255862_UP
DrugTetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SLC18A1 HLCS ZZEF1 RGS3 ZFX

8.82e-051985257473_UP
Drug0225151-0000 [351320-15-5]; Down 200; 10uM; MCF7; HT_HG-U133A

DOHH DNAJA4 APC GRIK5 SNRNP70

8.82e-051985256384_DN
DrugTrimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A

DNAJA4 HLCS GRIK5 SLC24A1 BAHCC1

8.82e-051985251502_UP
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

MAPT MAP3K14 DACH1 APC ARFGEF2

9.03e-051995255701_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A

MAPT APC ZZEF1 DNMT3B BAHCC1

9.03e-051995252683_DN
Drugrapamycin; Up 200; 0.1uM; HL60; HG-U133A

SLC18A1 HLCS COL5A3 SLC24A1 DNMT3B

9.03e-05199525362_UP
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

MAPT EPB41L5 GRIK5 SLC24A1 SLC25A37

9.03e-051995254985_DN
DrugRiboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A

DACH1 ITGA10 EPB41L5 GRIK5 ZZEF1

9.03e-051995254485_UP
DrugDextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; HL60; HT_HG-U133A

BBS7 DACH1 APC SLC24A1 ZFX

9.03e-051995251281_DN
DrugNicergoline; Down 200; 8.2uM; MCF7; HT_HG-U133A

DNAJA4 APC HLCS GRIK5 BAHCC1

9.03e-051995252220_DN
DrugAC1MF7BR

MAP3K14 APC DNMT3B

1.39e-0444523CID002867154
Diseasetemporal lobe epilepsy (is_implicated_in)

MAPT PDYN

2.92e-055512DOID:3328 (is_implicated_in)
DiseaseAngle Closure Glaucoma

COL11A1 GLIS3

6.12e-057512C0017605
Diseaseprimary angle closure glaucoma

COL11A1 GLIS3

1.59e-0411512EFO_1001506
DiseaseRespiratory Depression

MAPT PDYN

2.26e-0413512C0235063
DiseaseRespiratory Insufficiency

MAPT PDYN

2.26e-0413512C0035229
DiseaseRespiratory Failure

MAPT PDYN

2.26e-0413512C1145670
Diseasehematocrit

MAPT DNAJA4 GLIS3 EPB41L5 HLCS RGS3 SLC25A37 BAHCC1

3.18e-041011518EFO_0004348
DiseaseOsteoarthritis of hip

COL11A1 MAPT

5.46e-0420512C0029410
DiseaseSplenomegaly

MAPT APC

6.62e-0422512C0038002
Diseaseblood rubidium measurement

ARFGEF2 PRPF18

9.27e-0426512EFO_0021529
DiseaseAbnormality of refraction

MAPT ZBTB4 GLIS3 ECEL1 ZZEF1 RGS3

1.04e-03673516HP_0000539
DiseaseAutosomal Dominant Parkinsonism

MAPT PDYN

1.08e-0328512C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

MAPT PDYN

1.08e-0328512C0752097
DiseaseParkinsonism, Experimental

MAPT PDYN

1.08e-0328512C0752101
DiseaseAutosomal Recessive Parkinsonism

MAPT PDYN

1.08e-0328512C0752100
DiseaseFamilial Juvenile Parkinsonism

MAPT PDYN

1.08e-0328512C0752104
DiseaseRamsay Hunt Paralysis Syndrome

MAPT PDYN

1.08e-0328512C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

MAPT PDYN

1.08e-0328512C1868675
Diseaselung small cell carcinoma (is_implicated_in)

KMT2D DNMT3B

1.08e-0328512DOID:5409 (is_implicated_in)
DiseaseParkinsonism, Juvenile

MAPT PDYN

1.24e-0330512C0752105
DiseaseParkinsonian Disorders

MAPT PDYN

1.24e-0330512C0242422
Diseasecreatinine measurement

CDH20 MAP3K14 GLIS3 DACH1 EPB41L5 PIP5K1A BTAF1

1.54e-03995517EFO_0004518

Protein segments in the cluster

PeptideGeneStartEntry
KGGSGDREEEQHRML

AHRR

371

A9YTQ3
VAGEGKDRHLEGTMA

BAHCC1

416

Q9P281
GDGVKDLLVGRDDGM

BBS7

251

Q8IWZ6
MKGDTRHLNGEEDAG

DNMT3B

1

Q9UBC3
TLEADRGGKFHMVDG

AHSA1

241

O95433
KGHTLAGEEFMGLGL

ARFGEF2

1026

Q9Y6D5
GMKDGQKILFHGEGD

DNAJA4

216

Q8WW22
RGGGIAHKDLDRVMD

BCKDK

316

O14874
EGDLAGHDMGHESKR

DACH1

556

Q9UI36
MVRHEAGEALGAIGD

DOHH

86

Q9BU89
AGEGRGGHMVKIAVD

C17orf113

631

A0A1B0GUU1
DGEDNHMDGDKGARR

DRAP1

96

Q14919
TGHRKMSGADTVGDD

RGS3

1001

P49796
EDGMHALGAMRALGE

MON1B

371

Q7L1V2
GEPVDLHMKLGDSGE

LPIN3

71

Q9BQK8
KSDSEGGDLDKHMGD

MDN1

4751

Q9NU22
GGDLDKHMGDLNGEE

MDN1

4756

Q9NU22
EGEIHAEDGEMKGNE

SLC24A1

811

O60721
AGLGHGMDRVGSEIE

HNRNPM

421

P52272
DGMEHVGRDDPKALG

HLCS

56

P50747
MEEVREGHALGGGME

NCCRP1

1

Q6ZVX7
DMGLKGDRGEVGQIG

COL11A1

791

P12107
GEGDGDSMGHEDLYK

PDYN

191

P01213
TGAGKTHTMLGREGD

KIF18B

111

Q86Y91
ARRGGTMETDDHMGG

PIP5K1A

371

Q99755
GKHTLGENIADMGGL

ECEL1

666

O95672
EMLLTGKEGHGNKDG

EPB41L5

681

Q9HCM4
HGKSGGKMGDSTLEE

BTAF1

316

O14981
GKLHSDMDRGDGSIK

CDH20

81

Q9HBT6
EHMGESLSLKAGGGD

ARFGEF3

1971

Q5TH69
TLDDDGEMDGIGGKH

GLIS3

331

Q8NEA6
MHLGMSLLETDGDGG

ITGA10

106

O75578
NVHGGILADDMGLGK

HLTF

286

Q14527
EEDHRAKGLGMENIG

GRIK5

791

Q16478
LMAHGREGFLKGEDG

CASP14

86

P31944
KMAHGYGEESEEERG

CHGB

396

P05060
GHMGREGREGEKGAK

COL5A3

1316

P25940
LGRGSFGEVHRMEDK

MAP3K14

406

Q99558
KEELRGGGGDMAEPS

SNRNP70

306

P08621
TGGFRRGKKMGHDVD

DNTT

331

P04053
RMDGDSRDGGGGKDA

SLC25A37

16

Q9NYZ2
DHMVTLRDQGEGGDL

SANBR

461

Q6NSI8
EKHSPRNMGGILGED

APC

2061

P25054
HKGSEEEHDALIGMG

TNRC18

1576

O15417
EEHDALIGMGKARGR

TNRC18

1581

O15417
EEGEGTGSMLGARVH

STYXL2

296

Q5VZP5
AGEGDRMEGIGAAKV

ZBTB4

901

Q9P1Z0
MEDHAGTYGLGDRKD

MAPT

11

P10636
EGHEAVEGDLGGMCE

SNX19

331

Q92543
ELGDDDRKGMHTGGI

nan

56

Q6ZVL8
LDDAGKIEHDGSSGM

ZFX

216

P17010
LGGVKPEGHGDDHEM

ZZEF1

1811

O43149
EEGHGEEINMGEKLS

ZCWPW2

291

Q504Y3
ALGESLGKGDDHKDM

PRPF18

171

Q99633
DDHERGRAMGTALGG

SLC18A1

221

P54219
DTDELLKGEGGVEHM

KMT2D

1646

O14686