Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DAPK1	DAPK2 DAPK1 DAPK3	3.78e-07	3	136	3	IPR020676
Domain	VWF_A	COL6A3 VWA8 ITIH2 SVEP1 ITIH3 HMCN2 SEC24C XRCC6	6.30e-07	99	136	8	IPR002035
Domain	-	COL6A3 ITIH2 SVEP1 ITIH3 SEC24C XRCC6	1.65e-05	74	136	6	3.40.50.410
Domain	VWFA	COL6A3 VWA8 ITIH2 SVEP1 ITIH3 HMCN2	2.97e-05	82	136	6	PS50234
Domain	VWA	COL6A3 VWA8 ITIH2 SVEP1 ITIH3 HMCN2	3.40e-05	84	136	6	SM00327
Domain	ARM-type_fold	CAND1 CLTCL1 IPO4 MEI1 AP3B1 RYR3 AP2A1 XPO6 RPTOR INTS4 UNC79	3.87e-05	339	136	11	IPR016024
Domain	VWA	COL6A3 VWA8 ITIH2 SVEP1 ITIH3	5.39e-05	56	136	5	PF00092
Domain	HEAT	CAND1 IPO4 RPTOR INTS4	4.08e-04	48	136	4	PF02985
Domain	DS_RBD	MRPL44 ADAR DHX9	4.56e-04	21	136	3	PS50137
Domain	Aminotrans_3	PHYKPL AGXT2	5.19e-04	5	136	2	IPR005814
Domain	Aminotran_3	PHYKPL AGXT2	5.19e-04	5	136	2	PF00202
Domain	AA_TRANSFER_CLASS_3	PHYKPL AGXT2	5.19e-04	5	136	2	PS00600
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CAND1 IARS1 BAG2 SPAG9 IPO4 AP3B1 ADAR DHX9 ESYT2 SEC24C DDX18 NUP210 DLAT SCFD1 USP39 PLS3 XRCC6 KDM1A SYNCRIP	1.75e-11	638	142	19	33239621
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CAND1 ANK1 IARS1 BAG2 IPO4 RREB1 AP3B1 ADAR LAP3 DHX9 PHF2 ESYT2 IGF2BP2 SEC24C AP2A1 USP42 BAZ2A DDX18 IQSEC1 DDX23 ALDH4A1 SCFD1 PPIP5K2 XRCC6 KDM1A SYNCRIP	2.52e-11	1318	142	26	30463901
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	RAF1 PITRM1 VWA8 MRPL44 BAG2 DAPK3 TACC2 SPAG9 ARMCX4 DHX9 SLC30A6 ESYT2 IGF2BP2 ALMS1 BAZ2A RPTOR DDX18 DLAT ALDH4A1 SCFD1 GFM1 YME1L1 DDX28 XRCC6 RBFA SYNCRIP	3.87e-10	1496	142	26	32877691
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RAF1 CAND1 FNTA IARS1 BAG2 SPAG9 IPO4 AP3B1 ADAR LAP3 DHX9 IGF2BP2 AP2A1 SVIL AGFG1 DLAT SCFD1 USP39 PLS3 XRCC6 GOT1 SYNCRIP	1.78e-09	1149	142	22	35446349
Pubmed	Defining the membrane proteome of NK cells.	CAND1 CLTCL1 MED16 IARS1 CYP20A1 IPO4 ECE1 AP3B1 IFI16 ADAR BTN3A2 DHX9 ESYT2 AGO4 AP2A1 PRIM1 DDX18 NUP210 IQSEC1 YME1L1 XRCC6 SYNCRIP	2.40e-09	1168	142	22	19946888
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CAND1 VWA8 MED16 MRPL44 ADAR DHX9 PHF2 IGF2BP2 SEC24C AP2A1 USP42 VCAN DDX18 IQSEC1 ZNF638 INTS4 DDX23 USP39 PPIP5K2 XRCC6 SYNCRIP	3.41e-09	1082	142	21	38697112
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CAND1 FNTA IARS1 MRPL44 BAG2 IPO4 ADAR DHX9 IGF2BP2 HMCN2 SEC24C AP2A1 PRIM1 ZNF638 DLAT SCFD1 YME1L1 PLS3 DDX28 XRCC6 KDM1A RBFA SYNCRIP	5.36e-09	1335	142	23	29229926
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	CAND1 PITRM1 POU2F1 AP3B1 ADAR ESYT2 DLAT USP39 ZNF606 PLS3 XRCC6 WNK3 GOT1 SYNCRIP	5.52e-09	451	142	14	36168627
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	BAG2 TOPBP1 RREB1 IFI16 ADAR DHX9 PHF2 ESYT2 BRCA1 AP2A1 USP42 BAZ2A DDX18 EXO1 ZNF638 INTS4 DDX23 USP39 TMEM41B XRCC6 KDM1A SYNCRIP	1.52e-08	1294	142	22	30804502
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CAND1 PITRM1 IARS1 MRPL44 IPO4 AP3B1 ADAR LAP3 DHX9 PHF2 AP2A1 RPTOR PRIM1 DDX18 NUP210 DLAT SCFD1 USP39 GFM1 PLS3 XRCC6 KDM1A SYNCRIP	1.79e-08	1425	142	23	30948266
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	POU2F1 SPAG9 RREB1 IFI16 DHX9 ESYT2 SEC24C USP42 BAZ2A XPO6 RPTOR SVIL IQSEC1 EXO1 ZNF638 SCFD1 XRCC6	2.05e-08	774	142	17	15302935
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RAF1 VWA8 HAUS5 BAG2 CLSTN2 RREB1 PHF2 ARHGAP4 IGF2BP2 HMCN2 ALMS1 BRCA1 BAZ2A RPTOR DDX18 IQSEC1 DLAT YME1L1 KDM1A SORL1	3.12e-08	1116	142	20	31753913
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CAND1 IARS1 BAG2 IPO4 IFI16 ADAR DHX9 IGF2BP2 SEC24C AP2A1 BAZ2A RPTOR DDX18 IQSEC1 ZNF638 DDX23 DLAT SCFD1 YME1L1 XRCC6 KDM1A SYNCRIP	3.34e-08	1353	142	22	29467282
Pubmed	The death-associated protein kinases: structure, function, and beyond.	DAPK2 DAPK1 DAPK3	6.66e-08	3	142	3	16756490
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	BAG2 TOPBP1 ADAR DHX9 BRCA1 DDX18 SVIL NUP210 ZNF638 DDX23 USP39 PLS3 XRCC6 KDM1A SYNCRIP	8.08e-08	652	142	15	31180492
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	VWA8 RANBP3 MRPL44 IPO4 AP3B1 ADAR ESYT2 AP2A1 RPTOR INTS4 DDX23 DLAT GFM1 KDM1A	8.16e-08	560	142	14	35241646
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CAND1 MED16 MRPL44 TOPBP1 TACC2 ADAR DHX9 IGF2BP2 AP2A1 DDX18 EXO1 DLAT YME1L1 DDX28 XRCC6 SYNCRIP	9.59e-08	759	142	16	35915203
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CAND1 IARS1 HAUS5 BAG2 ADAR DHX9 IGF2BP2 SEC24C AP2A1 DDX18 SVIL NUP210 ZNF638 DDX23 USP39 XRCC6 KDM1A SYNCRIP	2.15e-07	1024	142	18	24711643
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	CAND1 IARS1 BAG2 IPO4 DHX9 ESYT2 IGF2BP2 SEC24C AP2A1 DDX18 NUP210 AGFG1 USP39 XRCC6 SYNCRIP	2.28e-07	707	142	15	19738201
Pubmed	Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.	BTN3A2 BTN3A1 ACE2	2.66e-07	4	142	3	39142074
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	FLVCR1 BAG2 DAPK3 GPRIN3 CTDSP1 SPAG9 BCAR1 AP3B1 PHF2 ESYT2 IGF2BP2 PPP3CC PRIM1 SVIL NUP210 ZNF638 INTS4 YME1L1	3.06e-07	1049	142	18	27880917
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	RAF1 CAND1 IARS1 MRPL44 PNKD ADAR DHX9 ESYT2 IGF2BP2 DDX18 NUP210 USP39 GFM1 XRCC6 SYNCRIP	3.13e-07	725	142	15	27025967
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	IFI16 ADAR DHX9 ARHGAP4 DDX18 USP39 XRCC6 SYNCRIP	3.19e-07	159	142	8	22751105
Pubmed	Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.	IARS1 IFI16 DHX9 DLAT XRCC6	3.60e-07	36	142	5	24147044
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RAF1 PITRM1 IARS1 SPAG9 IPO4 RREB1 AP3B1 DHX9 AP2A1 XPO6 RPTOR ZNF638 TMEM41B PPIP5K2 YME1L1 PLS3 TRAPPC9 KDM1A SYNCRIP SORL1	4.64e-07	1321	142	20	27173435
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAF1 RANBP3 DAPK2 DAPK3 BCAR1 ESYT2 ALMS1 RPTOR SVIL IQSEC1 AGFG1 EXO1 PPIP5K2 TRAPPC9 WNK3 SPATA13	5.16e-07	861	142	16	36931259
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RAF1 CAND1 PITRM1 FNTA SPAG9 IPO4 AP3B1 ESYT2 IGF2BP2 AP2A1 NUP210 GFM1 YME1L1 PLS3 KDM1A SYNCRIP SORL1	5.30e-07	974	142	17	28675297
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ANK2 VWA8 RANBP3 FLVCR1 MRPL44 BAG2 IPO4 AP3B1 DHX9 ESYT2 SEC24C BAZ2A DDX18 NUP210 DDX23 DLAT SCFD1 YME1L1 PLS3 XRCC6 SYNCRIP	7.18e-07	1487	142	21	33957083
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DSG3 IARS1 DAPK3 IPO4 IFI16 ADAR ITIH2 DHX9 IGF2BP2 AP2A1 PRIM1 DDX18 SVIL NUP210 ZNF638 USP39 PLS3 XRCC6 SYNCRIP	9.46e-07	1257	142	19	36526897
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	CAND1 CLTCL1 IARS1 DAPK1 GPRIN3 CLSTN2 IPO4 AP3B1 DHX9 AP2A1 DDX18 UNC79 HYDIN XRCC6 SYNCRIP	1.19e-06	807	142	15	30575818
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	IARS1 MRPL44 HAUS5 DHX9 ESYT2 SEC24C BAZ2A DDX18 DLAT USP39 PLS3 XRCC6 KDM1A RBFA SYNCRIP	1.23e-06	809	142	15	32129710
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	FNTA DAPK3 LAP3 DHX9 IGF2BP2 PRIM1 AGFG1 ALDH4A1 ALDH6A1 YME1L1 PLS3 DDX28 XRCC6 SYNCRIP	1.26e-06	704	142	14	32994395
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	PHYKPL RFK PITRM1 FPGS MRPL44 IREB2 PNKD LAP3 SLC30A6 AGXT2 DLAT ALDH4A1 GFM1 ALDH6A1 YME1L1 DDX28	1.34e-06	926	142	16	20877624
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	CAND1 IARS1 ADAR SVEP1 DHX9 IGF2BP2 DDX23 DLAT USP39 ALDH6A1 XRCC6 KDM1A GOT1 SYNCRIP	1.49e-06	714	142	14	28302793
Pubmed	Human transcription factor protein interaction networks.	PITRM1 IARS1 MRPL44 BAG2 POU2F1 SPAG9 RREB1 PHF2 IGF2BP2 ALMS1 BRCA1 DDX18 SVIL ZNF638 DLAT TRAPPC9 XRCC6 KDM1A SYNCRIP SORL1	1.56e-06	1429	142	20	35140242
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	ADAR DHX9 DDX23 DDX28 XRCC6 SYNCRIP	1.83e-06	89	142	6	22446626
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CAND1 ANK2 DAPK1 DAPK3 ARMCX4 IPO4 SEC24C AP2A1 RPTOR SVIL IQSEC1 UNC79 XRCC6 WNK3 KDM1A SPATA13	2.21e-06	963	142	16	28671696
Pubmed	Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.	DAPK1 DAPK3 SYNCRIP	2.30e-06	7	142	3	23071094
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	VWA8 IARS1 ECE1 MMP24 SEC24C DDX18 NUP210 ZNF638 MEDAG DDX23 TMEM41B YME1L1 XRCC6 KDM1A	2.80e-06	754	142	14	35906200
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SPAG9 IPO4 IGF2BP2 SEC24C BAZ2A DDX18 NUP210 ZNF638 DDX23 DLAT XRCC6 KDM1A SYNCRIP	3.05e-06	653	142	13	22586326
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	BAG2 IPO4 ADAR LAP3 DHX9 SEC24C USP42 DDX18 ZNF638 DDX23 DLAT USP39 GFM1 XRCC6 KDM1A SYNCRIP	3.10e-06	989	142	16	36424410
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	CAND1 PITRM1 IARS1 CYP20A1 SPAG9 IPO4 LAP3 DHX9 SEC24C AP2A1 DDX18 AGFG1 DLAT PLS3 XRCC6	3.35e-06	878	142	15	37223481
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RAF1 ANK2 VWA8 IREB2 AP3B1 ITIH2 ITIH3 PHF2 IGF2BP2 SEC24C AP2A1 DDX18 SVIL IQSEC1 DDX23 DLAT PLS3 DDX28 XRCC6	3.36e-06	1371	142	19	36244648
Pubmed	Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin.	ADAR DHX9 XRCC6	3.68e-06	8	142	3	15723802
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	IARS1 DHX9 IGF2BP2 USP39 XRCC6	4.43e-06	59	142	5	32382008
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	COL6A3 BAG2 SPAG9 ADAR RYR3 AP2A1 DLAT USH2A	5.24e-06	231	142	8	36597993
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	CAND1 PITRM1 IARS1 ADAR DHX9 SEC24C DLAT SCFD1 GFM1 PLS3 SYNCRIP	5.25e-06	484	142	11	31995728
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	RAF1 FNTA IARS1 RANBP3 PCDHB5 MRPL44 BAG2 SPAG9 IPO4 AP3B1 DHX9 IGF2BP2 XPO6 DDX23 USP39 UNC79 PLS3 SYNCRIP	5.32e-06	1284	142	18	17353931
Pubmed	PHF11 promotes DSB resection, ATR signaling, and HR.	BRCA1 EXO1 XRCC6	5.50e-06	9	142	3	28115467
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RAF1 CAND1 ANK2 IARS1 DAPK1 DAPK3 AP3B1 DHX9 SEC24C AP2A1 RPTOR VCAN SVIL IQSEC1 DLAT PLS3 TRAPPC9 GOT1 SYNCRIP	6.21e-06	1431	142	19	37142655
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	CAND1 IARS1 SPAG9 DHX9 ALMS1 SEC24C BRCA1 RPTOR XRCC6 KDM1A SYNCRIP	6.37e-06	494	142	11	26831064
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	IFI16 DHX9 IGF2BP2 DDX18 DDX23 DLAT USP39 XRCC6 SYNCRIP	6.54e-06	316	142	9	31665637
Pubmed	Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.	IARS1 ADAR DHX9 IGF2BP2 DDX23 SCFD1 PLS3 SYNCRIP	7.15e-06	241	142	8	23125841
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CAND1 IARS1 FLVCR1 BAG2 IPO4 AP3B1 ESYT2 AP2A1 XPO6 RPTOR NUP210 SCFD1 TMEM41B YME1L1 WNK3	7.77e-06	942	142	15	31073040
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	IREB2 DHX9 IGF2BP2 DDX18 USP39 PLS3 XRCC6 SYNCRIP	8.06e-06	245	142	8	35652658
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	MRPL44 TOPBP1 DAPK1 DHX9 IGF2BP2 USP42 DDX18 DENND2C INTS4 DDX23 USP39 DDX28 XRCC6	9.08e-06	723	142	13	34133714
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	CAND1 IPO4 DLAT USP39 PLS3 XRCC6	9.90e-06	119	142	6	35776542
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	BAG2 ADAR DHX9 AP2A1 ZNF638 DDX23 XRCC6 KDM1A SYNCRIP	1.17e-05	340	142	9	24332808
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAND1 PITRM1 VWA8 HAUS5 TOPBP1 ARHGAP4 AGO4 RPTOR SCFD1 PPIP5K2 KDM1A	1.21e-05	529	142	11	14621295
Pubmed	A protein interaction landscape of breast cancer.	RAF1 CAND1 VWA8 BAG2 DHX9 SEC24C BRCA1 AP2A1 SVIL YME1L1 XRCC6 SYNCRIP	1.23e-05	634	142	12	34591612
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	ZAN BAG2 PNKD ESYT2 CAPN7 SVIL IQSEC1 XRCC6 SYNCRIP	1.58e-05	353	142	9	27545878
Pubmed	Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways.	DAPK2 DAPK1	1.66e-05	2	142	2	31116076
Pubmed	Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells.	DAPK2 DAPK1	1.66e-05	2	142	2	22160140
Pubmed	DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.	ADAR DHX9	1.66e-05	2	142	2	28355180
Pubmed	Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing α2β subunits.	GLRA2 GLRB	1.66e-05	2	142	2	22606311
Pubmed	Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.	DAPK2 DAPK1	1.66e-05	2	142	2	18535204
Pubmed	Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint.	TOPBP1 BRCA1	1.66e-05	2	142	2	12810625
Pubmed	BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.	POU2F1 BRCA1	1.66e-05	2	142	2	29330289
Pubmed	Novel Cancer Therapeutics with Allosteric Modulation of the Mitochondrial C-Raf-DAPK Complex by Raf Inhibitor Combination Therapy.	RAF1 DAPK1	1.66e-05	2	142	2	26100670
Pubmed	A high-resolution genetic map of the nervous locus on mouse chromosome 8.	ANK1 FNTA	1.66e-05	2	142	2	9545640
Pubmed	EXO1 protects BRCA1-deficient cells against toxic DNA lesions.	BRCA1 EXO1	1.66e-05	2	142	2	38266640
Pubmed	Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.	POU2F1 BRCA1	1.66e-05	2	142	2	18000219
Pubmed	Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.	EXO1 XRCC6	1.66e-05	2	142	2	23610439
Pubmed	Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.	BTN3A2 BTN3A1	1.66e-05	2	142	2	21918970
Pubmed	The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.	BTN3A2 BTN3A1	1.66e-05	2	142	2	22846996
Pubmed	BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.	DHX9 BRCA1	1.66e-05	2	142	2	9662397
Pubmed	Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice.	ANK1 ANK2	1.66e-05	2	142	2	8471772
Pubmed	DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination.	DHX9 BRCA1	1.66e-05	2	142	2	34226554
Pubmed	CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.	BTN3A2 BTN3A1	1.66e-05	2	142	2	21113407
Pubmed	Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells.	ADAR DHX9	1.66e-05	2	142	2	38530197
Pubmed	A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.	SVIL KDM1A	1.66e-05	2	142	2	25684206
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	ANK2 IARS1 ADAR ESYT2 ZNF638 XRCC6 KDM1A SYNCRIP	1.67e-05	271	142	8	32433965
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	RFK PITRM1 VWA8 FPGS MRPL44 PNKD ADAR LAP3 AGXT2 DLAT ALDH4A1 GFM1 ALDH6A1 YME1L1 DDX28 RBFA	1.74e-05	1136	142	16	34800366
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	RFK IARS1 FPGS P2RX6 XPO6 RPTOR DDX23 TMEM41B XRCC6 NSMAF	1.87e-05	454	142	10	33226137
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CAND1 FLVCR1 GPRIN3 SPAG9 IPO4 AP3B1 DHX9 SLC30A6 SEC24C BRCA1 DDX18 ZNF638 SCFD1	1.94e-05	777	142	13	35844135
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CLTCL1 VWA8 IARS1 DHX9 NUP210 PKHD1 ZNF638	2.06e-05	202	142	7	24639526
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CLTCL1 IARS1 MRPL44 AP3B1 DHX9 PHF2 IGF2BP2 AP2A1 RPTOR DDX18 NUP210 SCFD1 PLS3 XRCC6 SPATA13 SYNCRIP	2.08e-05	1153	142	16	29845934
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	CAND1 SPAG9 LAP3 ESYT2 ALMS1 BRCA1 PRIM1 DDX18 DDX23 USH2A XRCC6 KDM1A	2.11e-05	670	142	12	22990118
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	PITRM1 VWA8 LAP3 DLAT GFM1 ALDH6A1 XRCC6	2.13e-05	203	142	7	35012549
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	MRPL44 BAG2 ADAR IGF2BP2 AGO4 ZNF638 INTS4 WNK3 KDM1A SYNCRIP	2.17e-05	462	142	10	31138677
Pubmed	Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation.	IARS1 DHX9 VCAN SYNCRIP	2.17e-05	40	142	4	16210410
Pubmed	Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.	DHX9 IGF2BP2 GFM1 PLS3 XRCC6	2.52e-05	84	142	5	19135240
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	PHYKPL RFK PITRM1 FPGS IREB2 PNKD LAP3 SLC30A6 AGXT2 DLAT ALDH4A1 GFM1 ALDH6A1 YME1L1 DDX28	2.66e-05	1047	142	15	18614015
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	VWA8 MRPL44 BAG2 DAPK1 SPAG9 BCAR1 DHX9 PHF2 IGF2BP2 GLRB ZNF638 DDX28 XRCC6 SYNCRIP	2.67e-05	922	142	14	27609421
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CAND1 FNTA IARS1 RANBP3 BAG2 IREB2 SPAG9 BCAR1 IPO4 AP3B1 LAP3 DHX9 SEC24C AGFG1 PLS3 XRCC6 GOT1 SYNCRIP	2.84e-05	1455	142	18	22863883
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	CAND1 AP3B1 DHX9 SEC24C XPO6 ZNF638 DDX23 USP39 XRCC6 KDM1A SYNCRIP	2.90e-05	582	142	11	20467437
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	CAND1 CLTCL1 IARS1 BAG2 IPO4 DHX9 INTS4 XRCC6 SYNCRIP	2.99e-05	383	142	9	29331416
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	IPO4 AP3B1 ADAR LAP3 DHX9 IGF2BP2 SEC24C AP2A1 ALDH4A1 SCFD1 YME1L1 KDM1A	3.42e-05	704	142	12	29955894
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	CAND1 TOPBP1 DHX9 IGF2BP2 INTS4 DDX23 USP39 KDM1A SYNCRIP	3.44e-05	390	142	9	17643375
Pubmed	Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.	IREB2 DLAT USP39 PLS3 SYNCRIP	3.52e-05	90	142	5	31280863
Interaction	H2AC4 interactions	CAND1 IARS1 POU2F1 BCAR1 AP3B1 DHX9 ACE2 ALMS1 SEC24C BRCA1 DDX18 SVIL LRRC27 ZNF638 DDX23 UNC79 XRCC6 SYNCRIP	1.64e-08	506	141	18	int:H2AC4
Interaction	CIT interactions	RAF1 CLTCL1 VWA8 IARS1 DAPK2 BAG2 DAPK3 RREB1 IFI16 ADAR DHX9 PHF2 ACE2 IGF2BP2 ALMS1 SEC24C BRCA1 AP2A1 DDX18 SVIL NUP210 ZNF638 INTS4 DDX23 USP39 PLS3 DDX28 XRCC6 KDM1A SYNCRIP	6.25e-08	1450	141	30	int:CIT
Interaction	KIF20A interactions	RAF1 CLTCL1 ANK2 VWA8 IARS1 HAUS5 BAG2 SPAG9 IFI16 ADAR DHX9 ACE2 IGF2BP2 AGO4 ALMS1 BRCA1 AP2A1 DDX18 SVIL ZNF638 YME1L1 DDX28 XRCC6 SYNCRIP	2.85e-07	1052	141	24	int:KIF20A
Interaction	SCARNA22 interactions	IFI16 ADAR DHX9 ARHGAP4 DDX18 USP39 XRCC6 SYNCRIP	1.80e-06	118	141	8	int:SCARNA22
Interaction	BAP1 interactions	RAF1 CAND1 FNTA IARS1 BAG2 SPAG9 IPO4 AP3B1 ADAR LAP3 DHX9 IGF2BP2 BRCA1 AP2A1 SVIL AGFG1 EXO1 DLAT SCFD1 USP39 PLS3 XRCC6 KDM1A GOT1 SYNCRIP	4.28e-06	1314	141	25	int:BAP1
Interaction	NR2C2 interactions	CAND1 ANK1 IARS1 BAG2 IPO4 RREB1 AP3B1 ADAR LAP3 DHX9 PHF2 ESYT2 IGF2BP2 SEC24C AP2A1 USP42 BAZ2A DDX18 IQSEC1 DDX23 ALDH4A1 SCFD1 PPIP5K2 XRCC6 KDM1A SYNCRIP	4.30e-06	1403	141	26	int:NR2C2
Interaction	STIP1 interactions	CAND1 IARS1 BAG2 POU2F1 SPAG9 IPO4 AP3B1 ADAR DHX9 ESYT2 SEC24C BRCA1 DDX18 NUP210 DLAT SCFD1 USP39 PLS3 XRCC6 KDM1A SYNCRIP	6.92e-06	1006	141	21	int:STIP1
Interaction	C9orf78 interactions	VWA8 RANBP3 MRPL44 BCAR1 IPO4 AP3B1 ADAR ESYT2 AP2A1 RPTOR INTS4 DDX23 DLAT USP39 GFM1 KDM1A	7.27e-06	620	141	16	int:C9orf78
Interaction	ARHGAP24 interactions	CAND1 PITRM1 POU2F1 AP3B1 ADAR ESYT2 DLAT USP39 ZNF606 PLS3 XRCC6 WNK3 GOT1 SYNCRIP	8.25e-06	486	141	14	int:ARHGAP24
Interaction	GTF3C4 interactions	RAF1 DAPK1 SPAG9 IFI16 ADAR BRCA1 ZNF638 XRCC6 KDM1A	9.63e-06	195	141	9	int:GTF3C4
Interaction	RBBP8 interactions	RAF1 TOPBP1 AP3B1 BRCA1 EXO1 XRCC6 KDM1A	2.42e-05	122	141	7	int:RBBP8
Interaction	TIA1 interactions	CAND1 BCAR1 LAP3 DHX9 AP2A1 RPTOR DLAT ATP1B2 GOT1 SYNCRIP	2.44e-05	275	141	10	int:TIA1
Interaction	SSRP1 interactions	RAF1 CAND1 IFI16 ADAR DHX9 PHF2 ACE2 SEC24C BRCA1 EXO1 ZNF638 INTS4 DDX23 USP39 XRCC6 SYNCRIP	2.48e-05	685	141	16	int:SSRP1
Interaction	LARP7 interactions	RAF1 CAND1 CLTCL1 IARS1 MRPL44 BAG2 SPAG9 AP3B1 IFI16 DHX9 PHF2 ACE2 IGF2BP2 BRCA1 BAZ2A DDX18 NUP210 DDX23 XRCC6 SPATA13 SYNCRIP	3.14e-05	1113	141	21	int:LARP7
Interaction	CSDE1 interactions	RAF1 CAND1 BAG2 DHX9 ACE2 IGF2BP2 SEC24C BRCA1 XRCC6 SYNCRIP	3.21e-05	284	141	10	int:CSDE1
Interaction	METTL17 interactions	RAF1 PHYKPL PITRM1 VWA8 MRPL44 IGF2BP2 DLAT ALDH4A1 GFM1 DDX28 RBFA SYNCRIP	3.29e-05	411	141	12	int:METTL17
Interaction	WWOX interactions	CAND1 DSG3 IARS1 BAG2 FRS3 CTDSP1 DHX9 ESYT2 IGF2BP2 SEC24C BRCA1 IQSEC1 DLAT USP39 KDM1A	3.44e-05	627	141	15	int:WWOX
Interaction	RBM14 interactions	RAF1 CAND1 AP3B1 IFI16 ADAR DHX9 ACE2 IGF2BP2 AATK BRCA1 DDX18 ZNF638 XRCC6 SYNCRIP	3.46e-05	553	141	14	int:RBM14
Interaction	ALYREF interactions	RAF1 CAND1 CLTCL1 GRK5 IREB2 DHX9 ACE2 SEC24C BRCA1 DDX23 XRCC6 SYNCRIP	3.70e-05	416	141	12	int:ALYREF
Interaction	IFI16 interactions	IFI16 ADAR DHX9 IGF2BP2 BRCA1 BAZ2A DDX18 SVIL ZNF638 DDX23 DLAT USP39 PLS3 DDX28 XRCC6 SYNCRIP	4.09e-05	714	141	16	int:IFI16
Interaction	RECQL4 interactions	CAND1 FNTA IARS1 MRPL44 BAG2 IPO4 ADAR DHX9 IGF2BP2 HMCN2 SEC24C BRCA1 AP2A1 PRIM1 ZNF638 DLAT SCFD1 YME1L1 PLS3 DDX28 XRCC6 KDM1A RBFA SYNCRIP	4.35e-05	1412	141	24	int:RECQL4
Interaction	SART3 interactions	RAF1 CAND1 IARS1 IFI16 DHX9 ACE2 AGO4 BRCA1 USP39 XRCC6	4.56e-05	296	141	10	int:SART3
Interaction	ECT2 interactions	CAND1 CLTCL1 IARS1 DAPK2 BAG2 SPAG9 DHX9 ESYT2 IGF2BP2 SVIL NUP210 DDX23 GFM1 PLS3 DDX28 XRCC6 KDM1A SYNCRIP	4.82e-05	887	141	18	int:ECT2
Interaction	NAT10 interactions	RAF1 CAND1 GRK5 IFI16 ACE2 BRCA1 DDX18 DDX23 XRCC6 SYNCRIP	5.39e-05	302	141	10	int:NAT10
Interaction	GAK interactions	CLTCL1 MED16 BAG2 BCAR1 ALMS1 SEC24C AP2A1 WNK3	5.64e-05	189	141	8	int:GAK
Interaction	LGALS9 interactions	CAND1 PITRM1 IARS1 ECE1 ADAR DHX9 SEC24C DLAT SCFD1 USP39 GFM1 PLS3 SYNCRIP SORL1	6.69e-05	588	141	14	int:LGALS9
Interaction	SAFB2 interactions	CAND1 FNTA RANBP3 BCAR1 IFI16 ACE2 DDX23 XRCC6	7.03e-05	195	141	8	int:SAFB2
Interaction	TARDBP interactions	RAF1 CAND1 MED16 MRPL44 BAG2 ADAR DHX9 ACE2 IGF2BP2 BRCA1 ATP1B2 XRCC6 SYNCRIP	7.56e-05	520	141	13	int:TARDBP
Interaction	SPDL1 interactions	CAND1 CLTCL1 FNTA IARS1 DHX9 RTP5 VCAN XRCC6 WNK3 KDM1A	7.66e-05	315	141	10	int:SPDL1
Interaction	AP2A2 interactions	RAF1 GRK5 BCAR1 IFI16 ACE2 AP2A1 INTS4 WNK3	8.10e-05	199	141	8	int:AP2A2
Interaction	MECP2 interactions	RAF1 CAND1 VWA8 MED16 MRPL44 ADAR DHX9 PHF2 IGF2BP2 SEC24C AP2A1 USP42 VCAN DDX18 IQSEC1 ZNF638 INTS4 DDX23 USP39 PPIP5K2 XRCC6 SYNCRIP	8.71e-05	1287	141	22	int:MECP2
Interaction	ABI3BP interactions	GRK5 ACE2 GOT1	9.11e-05	13	141	3	int:ABI3BP
Interaction	FN1 interactions	RAF1 CAND1 IARS1 BAG2 IPO4 ITIH2 DHX9 ACE2 ESYT2 IGF2BP2 SEC24C AP2A1 DDX18 NUP210 USP39 XRCC6 SYNCRIP	9.21e-05	848	141	17	int:FN1
Interaction	YWHAQ interactions	RAF1 GRK5 DAPK1 DAPK3 SPAG9 BCAR1 IFI16 DHX9 ACE2 BRCA1 USP42 RPTOR SVIL DENND2C AGFG1 EXO1 ZNF638 PPIP5K2 UNC79 SPATA13	1.03e-04	1118	141	20	int:YWHAQ
Interaction	EP300 interactions	ROBO4 CAND1 CLTCL1 ANK1 BAG2 TACC2 SPAG9 IPO4 AP3B1 IFI16 ADAR ITIH3 DHX9 ESYT2 SEC24C BRCA1 AP2A1 RPTOR DDX18 POLI DDX23 XRCC6 KDM1A	1.08e-04	1401	141	23	int:EP300
Interaction	TOP1 interactions	RAF1 CAND1 FNTA IFI16 ADAR DHX9 ACE2 BRCA1 PRIM1 EXO1 ZNF638 DDX23 USP39 XRCC6 SYNCRIP	1.11e-04	696	141	15	int:TOP1
Interaction	DLAT interactions	RAF1 VWA8 IFI16 DHX9 ACE2 DLAT GFM1 XRCC6 SYNCRIP	1.19e-04	269	141	9	int:DLAT
Interaction	AGO2 interactions	RAF1 CAND1 IFI16 DHX9 ESYT2 IGF2BP2 AGO4 BRCA1 AP2A1 IQSEC1 XRCC6 SYNCRIP	1.23e-04	472	141	12	int:AGO2
Interaction	MSH6 interactions	TOPBP1 IFI16 ADAR ACE2 BRCA1 EXO1 DDX23 XRCC6 KDM1A	1.26e-04	271	141	9	int:MSH6
Interaction	RAN interactions	RAF1 IARS1 RANBP3 BCAR1 IPO4 ACE2 BRCA1 XPO6 RPTOR NUP210 XRCC6 KDM1A	1.31e-04	475	141	12	int:RAN
Interaction	CCT8 interactions	RAF1 IARS1 IFI16 ACE2 BRCA1 RPTOR TMEM41B YME1L1 PLS3 XRCC6 KDM1A GOT1 NSMAF	1.32e-04	550	141	13	int:CCT8
Interaction	RUFY1 interactions	CAND1 FNTA IARS1 VSIG1 IPO4 DHX9 ESYT2 BRCA1 GLRA2 YME1L1 XRCC6 KDM1A	1.33e-04	476	141	12	int:RUFY1
Interaction	TRMT10C interactions	RAF1 CAND1 VWA8 ACE2 USP39 GFM1 ALDH6A1 DDX28	1.38e-04	215	141	8	int:TRMT10C
Interaction	SF3A3 interactions	CAND1 RANBP3 BAG2 IFI16 ACE2 BRCA1 ZNF638 DDX23 KDM1A SYNCRIP	1.43e-04	340	141	10	int:SF3A3
Interaction	METTL14 interactions	COL6A3 CLTCL1 BAG2 SPAG9 ADAR RYR3 DHX9 AP2A1 NUP210 DLAT USH2A XRCC6 SYNCRIP	1.52e-04	558	141	13	int:METTL14
Interaction	F2 interactions	RAF1 RANBP3 ACE2 P2RX6 GOT1	1.71e-04	74	141	5	int:F2
Interaction	SPTBN1 interactions	RAF1 ANK1 ANK2 GRK5 POU2F1 DAPK1 ADAR ACE2 BRCA1 SVIL XRCC6	1.88e-04	421	141	11	int:SPTBN1
Interaction	NOL11 interactions	RAF1 IFI16 ACE2 BRCA1 DDX23 XRCC6	1.91e-04	119	141	6	int:NOL11
Interaction	AR interactions	RAF1 CAND1 MED16 IARS1 RANBP3 POU2F1 DAPK3 IPO4 RREB1 IFI16 ADAR DHX9 BRCA1 SVIL INTS4 DDX23 XRCC6 KDM1A	1.97e-04	992	141	18	int:AR
Interaction	SRSF7 interactions	RAF1 CAND1 MRPL44 IREB2 DHX9 ACE2 ZNF638 DDX23 USP39 DDX28 XRCC6	2.04e-04	425	141	11	int:SRSF7
Interaction	CLTC interactions	RAF1 CAND1 CLTCL1 IARS1 BAG2 AP3B1 ADAR ACE2 SEC24C BRCA1 AP2A1 SVIL XRCC6 WNK3	2.07e-04	655	141	14	int:CLTC
Interaction	TOP3B interactions	CLTCL1 VWA8 IARS1 NICN1 GRK5 IREB2 IPO4 ECE1 BTN3A2 DHX9 IGF2BP2 AATK POMGNT2 AP2A1 XPO6 RPTOR SVIL DLAT TRAPPC9 DDX28 XRCC6 SPATA13 SYNCRIP	2.20e-04	1470	141	23	int:TOP3B
Interaction	SIRT7 interactions	RAF1 SPAG9 IPO4 IGF2BP2 SEC24C BAZ2A DDX18 NUP210 ZNF638 DDX23 DLAT USP39 XRCC6 KDM1A SYNCRIP	2.29e-04	744	141	15	int:SIRT7
Interaction	CIP2A interactions	TOPBP1 VSIG1 BCAR1 PNKD BRCA1 KDM1A SYNCRIP	2.43e-04	176	141	7	int:CIP2A
Interaction	ANKFY1 interactions	GRK5 ECE1 IFI16 LAP3 ARHGAP4 AATK ALMS1 KDM1A	2.61e-04	236	141	8	int:ANKFY1
Interaction	MRRF interactions	RAF1 VWA8 MRPL44 DDX18 DLAT GFM1 DDX28 RBFA SYNCRIP	2.61e-04	299	141	9	int:MRRF
Interaction	XRCC6 interactions	RAF1 CAND1 RANBP3 BAG2 POU2F1 IFI16 ADAR DHX9 PHF2 ACE2 BRCA1 BAZ2A RPTOR PRIM1 ZNF638 DLAT XRCC6	2.69e-04	928	141	17	int:XRCC6
Interaction	AP1B1 interactions	RAF1 IARS1 PNKD IFI16 ACE2 AATK AP2A1 WNK3	2.69e-04	237	141	8	int:AP1B1
Interaction	PRMT1 interactions	RAF1 CAND1 FNTA IARS1 IFI16 ADAR DHX9 ACE2 IGF2BP2 SEC24C BRCA1 DDX23 DLAT SAMD3 PLS3 KDM1A SYNCRIP	2.72e-04	929	141	17	int:PRMT1
Interaction	PTEN interactions	CAND1 PITRM1 BAG2 BCAR1 IPO4 ADAR RYR3 DHX9 AATK SEC24C RPTOR USP39 MAP2K6 YME1L1 XRCC6 KDM1A GOT1	2.72e-04	929	141	17	int:PTEN
Interaction	GRSF1 interactions	RAF1 CAND1 FNTA VWA8 MRPL44 IFI16 DHX9 IGF2BP2 DDX18 GFM1 DDX28 SYNCRIP	2.75e-04	515	141	12	int:GRSF1
Interaction	RIPK4 interactions	RAF1 CAND1 ANK2 VWA8 BAG2 IPO4 PNKD ESYT2 IQSEC1 SCFD1 YME1L1	3.08e-04	446	141	11	int:RIPK4
Interaction	PHB1 interactions	RAF1 CAND1 VWA8 IARS1 MRPL44 PNKD IFI16 ADAR DHX9 ACE2 ESYT2 IGF2BP2 DDX18 NUP210 USP39 TMEM41B GFM1 XRCC6 SYNCRIP	3.15e-04	1123	141	19	int:PHB1
Interaction	AATF interactions	RAF1 CAND1 DAPK3 IFI16 ADAR DHX9 IGF2BP2 BRCA1 DDX18 DDX23	3.21e-04	376	141	10	int:AATF
Interaction	PARP1 interactions	RAF1 CAND1 MRPL44 TOPBP1 POU2F1 DAPK1 IPO4 RREB1 IFI16 ADAR PHF2 ACE2 PPP3CC SEC24C BRCA1 AP2A1 DDX18 SVIL DLAT XRCC6 SYNCRIP	3.28e-04	1316	141	21	int:PARP1
Interaction	HNRNPU interactions	CAND1 CLTCL1 GRK5 MRPL44 POU2F1 SPAG9 IFI16 DHX9 PHF2 ACE2 BRCA1 AP2A1 DDX18 DDX23 USP39 TMEM41B HYDIN SYNCRIP	3.30e-04	1035	141	18	int:HNRNPU
Interaction	LAMP2 interactions	RAF1 FPGS FLVCR1 DAPK1 GPRIN3 CTDSP1 SPAG9 SLC30A6 ESYT2 AP2A1 RPTOR SCFD1 ALDH6A1	3.55e-04	609	141	13	int:LAMP2
Interaction	WDR76 interactions	RAF1 VWA8 IARS1 BAG2 AP3B1 DHX9 VCAN XRCC6 KDM1A SYNCRIP	3.72e-04	383	141	10	int:WDR76
Interaction	BIRC3 interactions	RAF1 CAND1 PITRM1 IARS1 MRPL44 IPO4 AP3B1 ADAR LAP3 DHX9 PHF2 AP2A1 RPTOR DDX18 NUP210 DLAT GFM1 PLS3 XRCC6 KDM1A SYNCRIP	3.93e-04	1334	141	21	int:BIRC3
Interaction	TRAPPC2 interactions	RAF1 CAND1 NICN1 DAPK1 SEC24C TRAPPC9	3.93e-04	136	141	6	int:TRAPPC2
Interaction	GTPBP10 interactions	RAF1 CAND1 VWA8 IFI16 DHX9 GFM1	3.93e-04	136	141	6	int:GTPBP10
Interaction	GRWD1 interactions	CAND1 IARS1 GRK5 IFI16 ADAR DHX9 ESYT2 AATK DDX18 LPIN2	4.28e-04	390	141	10	int:GRWD1
Interaction	RHOT2 interactions	TACC2 SPAG9 ARMCX4 DHX9 ESYT2 AATK ALMS1 SCFD1 TMEM41B	4.39e-04	321	141	9	int:RHOT2
Interaction	HGF interactions	RAF1 BRCA1 MAP2K6 SORL1	4.45e-04	51	141	4	int:HGF
Interaction	EED interactions	CAND1 IARS1 BAG2 DAPK1 IPO4 AP3B1 ADAR DHX9 IGF2BP2 SEC24C BRCA1 AP2A1 BAZ2A DDX18 SVIL NUP210 ZNF638 SCFD1 PLS3 XRCC6 KDM1A SYNCRIP	4.45e-04	1445	141	22	int:EED
Interaction	COX8A interactions	VWA8 MRPL44 ESYT2 IGF2BP2 DDX18 DLAT GFM1 YME1L1 RBFA	4.49e-04	322	141	9	int:COX8A
Interaction	OGDH interactions	RAF1 VWA8 DHX9 BRCA1 DLAT SCFD1 GFM1 DDX28	4.50e-04	256	141	8	int:OGDH
Interaction	SNAI1 interactions	CAND1 CLTCL1 IARS1 BAG2 CTDSP1 IPO4 DHX9 INTS4 USP39 XRCC6 KDM1A SYNCRIP	4.65e-04	546	141	12	int:SNAI1
Interaction	SH3BGRL2 interactions	RAF1 DAPK1 BCAR1	4.68e-04	22	141	3	int:SH3BGRL2
Interaction	PES1 interactions	RAF1 CAND1 AP3B1 IFI16 ACE2 XPO6 DDX18 DDX23	4.74e-04	258	141	8	int:PES1
Interaction	GOT1L1 interactions	GRK5 GOT1	4.79e-04	5	141	2	int:GOT1L1
Interaction	ALDH9A1 interactions	PITRM1 LAP3 ACE2 BRCA1 PLS3	4.95e-04	93	141	5	int:ALDH9A1
Interaction	ZNF638 interactions	CAND1 IFI16 ADAR RPTOR ZNF638 DDX23 XRCC6 RBFA	5.11e-04	261	141	8	int:ZNF638
Interaction	PLEKHA2 interactions	CLTCL1 SEC24C BRCA1 AP2A1 KDM1A	5.20e-04	94	141	5	int:PLEKHA2
Interaction	DDX21 interactions	RAF1 CLTCL1 GRK5 IFI16 ADAR DHX9 ACE2 IGF2BP2 BRCA1 DDX18 DDX23 USP39 XRCC6 SYNCRIP	5.21e-04	718	141	14	int:DDX21
Interaction	PRKRA interactions	RAF1 CAND1 IFI16 ADAR DHX9 ACE2 BRCA1 USP42 DDX18 SYNCRIP	5.22e-04	400	141	10	int:PRKRA
Interaction	ZYX interactions	CAND1 ANK2 BCAR1 LAP3 ACE2 ALMS1 SEC24C SVIL WNK3	5.24e-04	329	141	9	int:ZYX
Interaction	COMTD1 interactions	CAND1 IARS1 SPAG9 IPO4 ECE1 XPO6 INTS4	5.26e-04	200	141	7	int:COMTD1
Interaction	BTN3A1 interactions	BTN3A2 BTN3A1 ACE2	5.36e-04	23	141	3	int:BTN3A1
GeneFamily	Ankyrin repeat domain containing\|Death associated protein kinases	DAPK2 DAPK1 DAPK3	1.35e-06	5	94	3	1021
GeneFamily	Ankyrin repeat domain containing\|BRCA1 B complex	TOPBP1 BRCA1	1.59e-04	4	94	2	1335
GeneFamily	Glycine receptors	GLRA2 GLRB	2.65e-04	5	94	2	868
GeneFamily	DEAD-box helicases	DDX18 DDX23 DDX28	1.35e-03	42	94	3	499
GeneFamily	Adenosine receptors\|V-set domain containing	VSIG1 BTN3A2 BTN3A1 LY6G6F VCAN	1.61e-03	163	94	5	590
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN3A2 BTN3A1	2.69e-03	15	94	2	458
Coexpression	PUJANA_ATM_PCC_NETWORK	RAF1 DAPK2 TOPBP1 RREB1 AP3B1 IFI16 ADAR BTN3A1 DHX9 CDY1 ARHGAP4 PPP3CC BRCA1 BAZ2A DDX18 NUP210 SCFD1 PPIP5K2 YME1L1 IL5RA DDX28 NSMAF SYNCRIP	1.35e-06	1394	140	23	M9585
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_DN	PITRM1 IARS1 GRK5 BRCA1 PRIM1 GLRA2 DDX18 INTS4	4.00e-06	171	140	8	M2990
Coexpression	GSE27786_NKTCELL_VS_ERYTHROBLAST_UP	GRK5 ECE1 AP3B1 DHX9 SLC30A6 PHF2 ZNF606 DDX28	1.22e-05	199	140	8	M4865
Coexpression	GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN	LAP3 DHX9 LRR1 VCAN DDX18 SVIL AGFG1 NSMAF	1.22e-05	199	140	8	M6365
Coexpression	GSE34515_CD16_POS_MONOCYTE_VS_DC_UP	TOPBP1 ARMCX4 ALMS1 LPIN2 AGFG1 EXO1 YME1L1 DDX28	1.26e-05	200	140	8	M8765
Coexpression	GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN	CAND1 FNTA MED16 BAG2 CTDSP1 SLC30A6 DLAT SYNCRIP	1.26e-05	200	140	8	M7686
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	FNTA GPRIN3 IFI16 ADAR BTN3A2 BTN3A1 DHX9 ARHGAP4 ESYT2 PPP3CC USP42 XPO6 NUP210 LPIN2 AGFG1 ZNF638 SAMD3 YME1L1 XRCC6 NSMAF SPATA13 SORL1	1.41e-05	1492	140	22	M40023
Coexpression	IBRAHIM_NRF1_UP	BAG2 SPAG9 ECE1 RYR3 SEC24C DLAT SCFD1 YME1L1 PLS3 XRCC6 SYNCRIP	1.67e-05	420	140	11	M42509
Coexpression	LEE_BMP2_TARGETS_DN	IARS1 FPGS FLVCR1 HAUS5 TOPBP1 LRR1 BRCA1 DDX18 AGFG1 EXO1 MEDAG DLAT USP39 GFM1 XRCC6 SYNCRIP	2.77e-05	904	140	16	M2325
Coexpression	MANALO_HYPOXIA_DN	VWA8 IARS1 IPO4 BRCA1 DDX18 EXO1 DDX23 DLAT USP39	2.86e-05	292	140	9	M18562
Coexpression	GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN	DAPK2 GRK5 RPTOR LPIN2 IL1RL1 SAMD3 SPATA13	3.19e-05	166	140	7	M6701
Coexpression	LEE_BMP2_TARGETS_DN	IARS1 FPGS FLVCR1 HAUS5 TOPBP1 LRR1 BRCA1 DDX18 AGFG1 EXO1 MEDAG DLAT USP39 GFM1 XRCC6 SYNCRIP	3.50e-05	922	140	16	MM1068
Coexpression	GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP	IFI16 ADAR PRIM1 LPIN2 DLAT PLS3 SYNCRIP	3.86e-05	171	140	7	M5655
Coexpression	LOPEZ_MBD_TARGETS	RAF1 FNTA MED16 IARS1 GRK5 ARMCX4 MEI1 SVEP1 ITIH3 AATK PPP3CC DDX23 ATP1B2 TRAPPC9 KDM1A GOT1	5.19e-05	953	140	16	M4120
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP	RAF1 RFK GRK5 CYP20A1 SEC24C BRCA1 SAMD3	5.34e-05	180	140	7	M8127
Coexpression	SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP	HAUS5 TOPBP1 MEI1 NUP210 WNK3	6.64e-05	79	140	5	M14132
Coexpression	RIZ_ERYTHROID_DIFFERENTIATION	ANK1 POU2F1 DHX9 BRCA1 EXO1	7.94e-05	82	140	5	M16458
Coexpression	RIZ_ERYTHROID_DIFFERENTIATION	ANK1 POU2F1 DHX9 BRCA1 EXO1	9.42e-05	85	140	5	MM1106
Coexpression	GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP	IARS1 GPRIN3 LRR1 PRIM1 NUP210 EXO1 DLAT	1.00e-04	199	140	7	M8277
Coexpression	GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN	CAND1 FLVCR1 MRPL44 CYP20A1 USP42 PRIM1 USP39	1.03e-04	200	140	7	M3074
Coexpression	GOLDRATH_HOMEOSTATIC_PROLIFERATION	BAG2 DHX9 IGF2BP2 AGFG1 YME1L1 SORL1	1.59e-04	150	140	6	M3592
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ZAN FREM1 RYR3 PKHD1 USH2A UNC79 HYDIN	1.41e-07	184	142	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ZAN FREM1 RYR3 PKHD1 USH2A UNC79 HYDIN	1.41e-07	184	142	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ZAN FREM1 RYR3 PKHD1 USH2A UNC79 HYDIN	1.41e-07	184	142	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	IARS1 FLVCR1 DAPK1 POLI INTS4 ZNF606 NSMAF	1.26e-06	170	142	7	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	356C-Lymphocytic-ILC-ILC-2\|ILC / Donor, Lineage, Cell class and subclass (all cells)	NICN1 GRK5 VSIG1 RPTOR GFM1 PLS3 TRAPPC9	1.36e-06	172	142	7	4977e1f4deae781750e27a8054deccd336cfb74a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 HMCN2 RTP5 VCAN GLRA2 PPP1R1C ATP1B2	1.71e-06	178	142	7	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BTN3A1 SVEP1 VCAN GLRA2 PPP1R1C ATP1B2 PLS3	1.98e-06	182	142	7	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ANK2 VWA8 DAPK2 TACC2 SVIL PPP1R1C GOT1	2.64e-06	190	142	7	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 ANK2 CLSTN2 SVEP1 HMCN2 MEDAG WNK3	3.13e-06	195	142	7	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 HMCN2 VCAN	3.13e-06	195	142	7	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	IFI16 ADAR BTN3A2 BTN3A1 LAP3 LPIN2 SAMD3	3.24e-06	196	142	7	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 CLSTN2 SVEP1 FREM1 VCAN MEDAG	3.70e-06	200	142	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SVEP1 FREM1 RYR3 PKHD1 USH2A HYDIN	1.26e-05	160	142	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SVEP1 FREM1 RYR3 PKHD1 USH2A HYDIN	1.26e-05	160	142	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DAPK3 CLSTN2 IRAG1 RYR3 PHF2 SVIL	1.40e-05	163	142	6	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN RYR3 PKHD1 USH2A UNC79 HYDIN	1.72e-05	169	142	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	10x5'-blood-Mast-Mast_cells\|blood / Manually curated celltypes from each tissue	DAPK2 DAPK1 RYR3 LRRC27 IL1RL1 IL5RA	2.03e-05	174	142	6	a5838821bba2be790d32331ff529d466e9974268
ToppCell	10x5'-blood-Mast\|blood / Manually curated celltypes from each tissue	DAPK2 DAPK1 RYR3 LRRC27 IL1RL1 IL5RA	2.03e-05	174	142	6	3a8a253213b207e3ff56f94a74996b8d9ad47aa1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPAG9 CLSTN2 ECE1 RYR3 IGF2BP2 SVIL	2.31e-05	178	142	6	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ALMS1 BRCA1 NUP210 EXO1 INTS4 SAMD3	2.54e-05	181	142	6	e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 IRAG1 ACE2 AATK ATP1B2 SORL1	2.78e-05	184	142	6	9c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPRIN3 CAPN7 DDX18 ZNF638 SPATA13 SORL1	2.78e-05	184	142	6	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 IRAG1 ACE2 AATK ATP1B2 SORL1	2.78e-05	184	142	6	31dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A3 GRK5 SVEP1 HMCN2 VCAN MEDAG	2.87e-05	185	142	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAPK3 TACC2 CLSTN2 ECE1 RYR3 VCAN	2.87e-05	185	142	6	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL6A3 GRK5 SVEP1 FREM1 VCAN PLS3	3.05e-05	187	142	6	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A3 GRK5 SVEP1 FREM1 HMCN2 MEDAG	3.14e-05	188	142	6	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	COL6A3 ANK2 SVEP1 FREM1 VCAN MEDAG	3.14e-05	188	142	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ANK2 VWA8 DAPK2 TACC2 SVIL PPP1R1C	3.23e-05	189	142	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANK2 VWA8 DAPK2 TACC2 SVIL PPP1R1C	3.53e-05	192	142	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 VCAN	3.53e-05	192	142	6	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 SVEP1 FREM1 HMCN2 SVIL ATP1B2	3.53e-05	192	142	6	20ede290e01ad574afd122d72b59dbc52c595fad
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ITIH3 FREM1 HMCN2 SVIL ATP1B2	3.64e-05	193	142	6	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ITIH3 FREM1 HMCN2 SVIL LPIN2	3.64e-05	193	142	6	96c85b250d04b5f400512097d925061c6dc2906b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 ANK2 CLSTN2 SVEP1 FREM1 MEDAG	3.64e-05	193	142	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 VCAN	3.64e-05	193	142	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL6A3 BAG2 DAPK3 SVEP1 FREM1 VCAN	3.64e-05	193	142	6	cf3cbf79ccd34ddcf06ec6194a18a7afd7f91f39
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BAG2 IRAG1 RYR3 HMCN2 GLRB SVIL	3.64e-05	193	142	6	0256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 VCAN	3.74e-05	194	142	6	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 VCAN	3.74e-05	194	142	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK2 GRK5 BAG2 CLSTN2 IRAG1 SVEP1	3.85e-05	195	142	6	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 CLSTN2 SVEP1 VCAN MEDAG	3.85e-05	195	142	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	COL6A3 GRK5 CLSTN2 ECE1 SVEP1 VCAN	3.85e-05	195	142	6	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK2 GRK5 BAG2 CLSTN2 IRAG1 SVEP1	3.85e-05	195	142	6	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 DAPK2 GRK5 SVEP1 FREM1 VCAN	3.96e-05	196	142	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ITIH3 FREM1 HMCN2 SVIL LPIN2	3.96e-05	196	142	6	308fa54385ca34e9e590967d4553b84aad96c92f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 DAPK2 GRK5 SVEP1 FREM1 VCAN	3.96e-05	196	142	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 GRK5 CLSTN2 SVEP1 FREM1 VCAN	4.08e-05	197	142	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL6A3 GRK5 DAPK1 SVEP1 FREM1 VCAN	4.08e-05	197	142	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL6A3 GRK5 DAPK1 SVEP1 FREM1 VCAN	4.08e-05	197	142	6	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 GRK5 CLSTN2 SVEP1 FREM1 VCAN	4.08e-05	197	142	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RYR3 LY6G6F GLRA2 SVIL SPATA13	4.15e-05	120	142	5	2b7596946f9268c4202348adf3069decd8313bb0
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 ANK2 SVEP1 FREM1 RYR3 AATK	4.19e-05	198	142	6	0c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAG2 TOPBP1 LAP3 LRR1 PRIM1 EXO1	4.19e-05	198	142	6	c78ff8fc71dfcba1ac0c373bc90ea7b87c5699a4
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 CLSTN2 IRAG1 HMCN2 MEDAG ATP1B2	4.19e-05	198	142	6	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 SVEP1 FREM1 HMCN2 SVIL ATP1B2	4.19e-05	198	142	6	12cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 CLTCL1 GRK5 CLSTN2 IRAG1 ATP1B2	4.19e-05	198	142	6	b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A3 ANK2 SVEP1 FREM1 VCAN SPATA13	4.31e-05	199	142	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A3 ANK2 SVEP1 FREM1 VCAN SPATA13	4.31e-05	199	142	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 CLSTN2 SVEP1 VCAN MEDAG	4.43e-05	200	142	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ROBO4 ECE1 IFI16 ADAR LAP3 IGF2BP2	4.43e-05	200	142	6	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROBO4 ECE1 IFI16 ADAR LAP3 IGF2BP2	4.43e-05	200	142	6	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 SVEP1 FREM1 VCAN MEDAG	4.43e-05	200	142	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLTCL1 GRK5 GPRIN3 CLSTN2 IRAG1 ATP1B2	4.43e-05	200	142	6	78cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ROBO4 ECE1 IFI16 ADAR LAP3 IGF2BP2	4.43e-05	200	142	6	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 CLSTN2 SVEP1 VCAN MEDAG	4.43e-05	200	142	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 ANK2 SVEP1 FREM1 VCAN ATP1B2	4.43e-05	200	142	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	(01)_Cycling_Basal_(homeostasis)-(1)_24hpi\|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint	ARMCX4 PKHD1 DDX23 USH2A	7.84e-05	71	142	4	6aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	ANK2 ARHGAP4 AP2A1 PPIP5K2 SORL1	9.24e-05	142	142	5	0e0f8bb956ff89dc98e8fa56f8acac33e01a26dd
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPRIN3 CFAP65 SAMD3 HYDIN SORL1	9.55e-05	143	142	5	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPRIN3 RYR3 CFAP65 HYDIN SORL1	9.87e-05	144	142	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|368C / Donor, Lineage, Cell class and subclass (all cells)	RTP5 LPIN2 INTS4 SAMD3 IL5RA	1.09e-04	147	142	5	3ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK2 PCDHB5 IRAG1 P2RX6 SAMD3	1.12e-04	148	142	5	f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK2 PCDHB5 IRAG1 P2RX6 SAMD3	1.12e-04	148	142	5	4b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK2 PCDHB5 IRAG1 P2RX6 SAMD3	1.12e-04	148	142	5	55826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PM20D1 ITIH2 ITIH3 ALDH4A1 ALDH6A1	1.35e-04	154	142	5	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOPBP1 BRCA1 IL1RL1 MAP2K6 HYDIN	1.48e-04	157	142	5	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PCDHB5 MRPL44 IRAG1 VCAN	1.66e-04	161	142	5	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PCDHB5 MRPL44 IRAG1 VCAN	1.66e-04	161	142	5	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	droplet-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FPGS ITIH2 ITIH3 ALDH4A1 ALDH6A1	1.76e-04	163	142	5	a794540f2d8984f963c08f05175e4bc916fcc224
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 RYR3 ALMS1 BRCA1 SAMD3	1.76e-04	163	142	5	385b24e18df5ef92108483de312d6c85a1e6d145
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 IRAG1 SVEP1 VCAN SAMD3	1.76e-04	163	142	5	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 RYR3 ALMS1 BRCA1 SAMD3	1.76e-04	163	142	5	8004cc0b3428be08b89957b563cd8799f822d931
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 IRAG1 SVEP1 VCAN SAMD3	1.76e-04	163	142	5	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	facs-Kidney-nan-3m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 RYR3 PPP3CC BRCA1 SAMD3	1.87e-04	165	142	5	ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAG2 IPO4 ITIH2 AP2A1 GLRB	1.87e-04	165	142	5	7c771f22b58989572c939ed127e637ec28dc0dca
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 GNG14 GLRA2 MEDAG SAMD3	1.92e-04	166	142	5	ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 PHYKPL PCDHB5 PGBD1 MEDAG	1.92e-04	166	142	5	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAPK2 IRAG1 ITIH3 FREM1 ATP1B2	1.97e-04	167	142	5	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HMCN2 RTP5 VCAN PPP1R1C ATP1B2	2.03e-04	168	142	5	db56464b946ef9795bc41ed1099c864d49bd8900
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	RFK CLSTN2 ECE1 HMCN2 MEDAG	2.03e-04	168	142	5	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	GPRIN3 CLSTN2 IRAG1 SVEP1 IL5RA	2.09e-04	169	142	5	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 MEI1 ARHGAP4 NUP210 IQSEC1	2.14e-04	170	142	5	a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PCDHB5 CLSTN2 SVEP1 VCAN	2.14e-04	170	142	5	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 VCAN GLRA2 PPP1R1C ATP1B2	2.20e-04	171	142	5	a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BAG2 ITIH2 RYR3 GLRB SVIL	2.20e-04	171	142	5	fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRAG1 RYR3 HMCN2 VCAN SVIL	2.20e-04	171	142	5	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRAG1 RYR3 HMCN2 VCAN SVIL	2.20e-04	171	142	5	09e653973962fb884878089d281f0947f7a285f6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 DAPK2 SVEP1 P2RX6 IL1RL1	2.26e-04	172	142	5	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 VCAN GLRA2 ATP1B2 PLS3	2.26e-04	172	142	5	8b396d1e9173da104d467e42286379fe07cee257
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; PC3; HT_HG-U133A	MRPL44 HAUS5 DAPK3 PHF2 AATK AGO4 VCAN NUP210 ZNF606 ALDH6A1	4.13e-07	196	141	10	4494_DN
Drug	Epivincamine [6835-99-0]; Down 200; 11.2uM; HL60; HG-U133A	CAND1 BTN3A1 CAPN7 DDX18 NUP210 POLI DLAT PPIP5K2 YME1L1	3.64e-06	195	141	9	1783_DN
Drug	AC1L1CMQ	DSG3 VCAN GLRA2 GLRB	5.08e-06	19	141	4	CID000001968
Disease	pulse pressure measurement	COL6A3 ANK2 CYP20A1 PGBD1 BCAR1 RREB1 MEI1 PNKD SVEP1 ITIH3 RPTOR ZNF638 PPP1R1C HYDIN TRAPPC9 XRCC6 KDM1A RSKR	7.43e-05	1392	136	18	EFO_0005763
Disease	emphysema pattern measurement	VWA8 SVIL TRAPPC9	8.79e-05	19	136	3	EFO_0005850
Disease	X-12125 measurement	AGXT2 ALMS1	1.26e-04	4	136	2	EFO_0800707
Disease	N2,N2-dimethylguanosine measurement	AGXT2 ALMS1	5.80e-04	8	136	2	EFO_0021125
Disease	influenza A (H1N1)	ESYT2 DDX18 AGFG1 MEDAG	7.15e-04	87	136	4	EFO_1001488
Disease	22q11 partial monosomy syndrome	RREB1 SEC24C	7.43e-04	9	136	2	C3266101
Disease	Asymmetric crying face association	RREB1 SEC24C	9.26e-04	10	136	2	C0431406
Disease	22q11 Deletion Syndrome	RREB1 SEC24C	9.26e-04	10	136	2	C2936346
Disease	platelet aggregation	GRK5 IRAG1 LINC01556	1.18e-03	45	136	3	GO_0070527
Disease	cannabis dependence measurement	MEI1 DDX18 PKHD1	1.42e-03	48	136	3	EFO_0008457
Disease	Malignant neoplasm of breast	RAF1 ANK1 ANK2 POU2F1 TACC2 BCAR1 ADAR BTN3A2 BRCA1 DDX18 EXO1 PLS3 SORL1	1.42e-03	1074	136	13	C0006142
Disease	atrial fibrillation (is_implicated_in)	ANK2 AGXT2	1.85e-03	14	136	2	DOID:0060224 (is_implicated_in)
Disease	lean body mass	ECE1 AP3B1 IGF2BP2 AATK PRIM1 VCAN ZNF638	1.93e-03	379	136	7	EFO_0004995
Disease	hypertension (is_implicated_in)	ECE1 AGXT2 ACE2 BRCA1	2.42e-03	121	136	4	DOID:10763 (is_implicated_in)
Disease	DiGeorge Syndrome	RREB1 SEC24C	2.43e-03	16	136	2	C0012236
Disease	focal segmental glomerulosclerosis	IPO4 ALMS1	2.43e-03	16	136	2	EFO_0004236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	RREB1 SEC24C	2.43e-03	16	136	2	C0795907
Disease	Shprintzen syndrome	RREB1 SEC24C	2.43e-03	16	136	2	C0220704
Disease	Disorder of eye	FLVCR1 FREM1 ALMS1 VCAN USH2A	3.07e-03	212	136	5	C0015397
Disease	Dystonia, Paroxysmal	COL6A3 DLAT	3.07e-03	18	136	2	C0393588
Disease	DNA methylation	GPRIN3 AP3B1 FREM1 PHF2 ALMS1 DDX18 SVIL PKHD1 USH2A	3.46e-03	656	136	9	GO_0006306
Disease	diabetes mellitus	ANK1 RREB1 IGF2BP2	3.86e-03	68	136	3	EFO_0000400
Disease	unipolar depression	GRK5 PGBD1 MEI1 ECE1 BTN3A2 BTN3A1 VCAN SVIL PKHD1 ZNF638 SAMD3 LINC01556 TRAPPC9	3.87e-03	1206	136	13	EFO_0003761
Disease	Cleft palate	IARS1 POMGNT2 TRAPPC9	4.35e-03	71	136	3	HP_0000175

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEPIQGVNGVVQYPK	AGXT2	286	Q9BYV1
SEVQIAQLRFPVPKG	ESYT2	371	A0FGR8
NIFGTPEFVAPEIVN	DAPK1	176	P53355
FIQFKKPIVVSVNGP	CDY1	376	Q9Y6F8
PPVGNIVSFEQKATV	VCAN	396	P13611
NNKGENIPTVEAPVV	BTN3A1	181	O00481
FTAVATNQPPKIFVA	BCAR1	766	P56945
QQVEGEFTQKPGFPK	BAZ2A	1726	Q9UIF9
KLVPLVQATFPENAV	ANK1	1086	P16157
FLGPKSSLDFQVVQP	ALMS1	3116	Q8TCU4
PNPENFVGAGIIQTK	AP2A1	921	O95782
KVANEPVLAFTQGSP	ALDH4A1	31	P30038
PSVFQQPVIFLGADV	AGO4	576	Q9HCK5
VPDGIVPKNLTDQFT	CLSTN2	366	Q9H4D0
QPQIFAKTQTEAIPG	ARMCX4	321	Q5H9R4
FFPEDPVKIVRAQGQ	PHYKPL	26	Q8IUZ5
IAAPQNFTPSVIFQK	AP3B1	1011	O00203
VPPIVFVQDKGNAAL	RBFA	176	Q8N0V3
ILKVVDPTPEQFQAF	RAF1	376	P04049
AIAPPVFVFQKDKGQ	RANBP3	11	Q9H6Z4
TQPGTVFPLKIAQDF	PCDHB5	146	Q9Y5E4
DPQNTVKVQVLYPDG	INTS4	856	Q96HW7
TKQSNVEVPFFPARV	IREB2	71	P48200
VKFFVAVPGQVISPQ	SPAG9	1226	O60271
GRDASIPQFKPEIQV	LY6G6F	266	Q5SQ64
GVKFNVIPPVAQATV	PM20D1	346	Q6GTS8
VPQVQAVFPEGALTK	ANK2	1176	Q01484
NANEPPLVFVGKGIT	LAP3	271	P28838
TNPFPAVEPAVVKFV	NUP210	731	Q8TEM1
GIDQPPFGIFVVDKN	DSG3	91	P32926
TIFQFKNKTGPQPVT	MMP24	621	Q9Y5R2
GNFVGPTIISNVKPN	ALDH6A1	396	Q02252
PQNVVFDVQIPKGAF	ITIH2	101	P19823
LFGNTFEQPKVLPVI	LRR1	301	Q96L50
FNVLIQVPPMFQKVG	HMCN2	2731	Q8NDA2
EPGQASQIKVTFQPL	CFAP65	296	Q6ZU64
QPLVAVKFLNVTPNV	ATP1B2	241	P14415
VPGADIKVLINFNAP	IQSEC1	831	Q6DN90
PAVQLADAQVVFKPL	KIAA1109	2431	Q2LD37
PKEGPAVVGQFIQDV	CAND1	811	Q86VP6
QQPSVGTEIFVGKIP	SYNCRIP	156	O60506
AVVPKFNALNLPGQT	IRAG1	691	Q9Y6F6
QFVTPADVVSGNPKL	PLS3	351	P13797
FGIKNFSAIINPPQA	DLAT	571	P10515
VPKVGTVQVTLFNPN	FAM214B	421	Q7L5A3
FKPVNNADFIIPVEI	CTDSP1	106	Q9GZU7
QVPEAFTNPLKVTEG	FREM1	776	Q5H8C1
NIFGTPEFVAPEIVN	DAPK3	176	O43293
NPKAQLVLVGATFPE	DDX28	321	Q9NUL7
GVAFDPELLQKQPVN	RSKR	361	Q96LW2
TEQAKNDPFLVGIPA	GNG14	41	A0A1W2PPG7
IRPNFKGIPVDVVVN	GLRB	71	P48167
VIITGPPEAQFKAQG	IGF2BP2	476	Q9Y6M1
GFVQPQGPKANILVS	POMGNT2	246	Q8NAT1
QRKVVPTFEAVAPQS	HAUS5	426	O94927
KVPPFVDLNVNSNEG	DDX18	616	Q9NVP1
QGFDPPIIIFVNQKK	DDX23	661	Q9BUQ8
QEAVKNFFPPGNEVV	MEDAG	171	Q5VYS4
TQTNGLDFQKQPVPV	POU2F1	21	P14859
LDFQKQPVPVGGAIS	POU2F1	26	P14859
IFQQISPVVGDKQPT	MED16	321	Q9Y2X0
QDQGERPPLVVFKAS	MEI1	726	Q5TIA1
LQKVDQFDPFTVPTI	PRIM1	336	P49642
NIKPVQTVNITAGFP	BRCA1	916	P38398
VPHGPVDQKFQSIVI	BAG2	146	O95816
FPVIGAPAQNEIKEV	IL1RL1	211	Q01638
FLVNVNGSPEPVKLT	HYDIN	541	Q4G0P3
PGVPEVFKRSFQIQI	HYDIN	1461	Q4G0P3
VGPPAVKEVVNFTCQ	HYDIN	4626	Q4G0P3
LPPVNFTIKVTGLAQ	IL5RA	31	Q01344
FPDIISGPQQTQKVF	KDM1A	196	O60341
KFQVVINGREFPPAE	ADAR	536	P55265
IFNIIPSTFLPKQEG	CAPN7	781	Q9Y6W3
NIFGTPEFVAPEIVN	DAPK2	186	Q9UIK4
PQVFLQPGQVKFVLG	FRS3	231	O43559
SGVVPFIFQAKNADP	COL6A3	966	P12111
LTVPFGQKPNIDVTD	ACE2	281	Q9BYF1
VFAEVPQAQPVLVFK	GOT1	6	P17174
ISYIPQVIQQFPGKD	DENND2C	506	Q68D51
NAKGENIPAVEAPVV	BTN3A2	181	P78410
VELQNGPKAGTFPVN	FLVCR1	36	Q9Y5Y0
FKGPPVNVTCNIFIN	GLRA2	66	P23416
EAGPNQTFEVPNKII	IFI16	281	Q16666
NGYPKPVVQITLQDV	NSMAF	226	Q92636
IFKQGVPAFTVLQPE	FPGS	246	Q05932
PTKNEIVFPAGILQA	ECE1	571	P42892
INQVFGNGPVTPEKI	CYP20A1	306	Q6UW02
PGVFNEVQKAPATFN	GPRIN3	81	Q6ZVF9
TPKSPVFIAQVGQDL	GRK5	111	P34947
SNIPKQFVPAVEKGF	GFM1	576	Q96RP9
GVFKPNQQTVLLPES	POLI	236	Q9UNA4
GQVPPLVTTNFLVKD	SEC24C	351	P53992
ALENFVENLGPKVQP	IPO4	461	Q8TEX9
QEGNPAPFIINTVKR	LINC01556	6	Q5JQF7
VPVALNIGKLAQFEP	DHX9	306	Q08211
VKPPQGENVFFLVTN	P2RX6	101	O15547
GTPFQQLKQVVEEPS	MAP2K6	261	P52564
QVKGSLALPFPADVQ	RTP5	416	Q14D33
EAPPEGTVNVFVKTQ	USH2A	2326	O75445
VPPAVLQQTFFAVIG	MRPL44	186	Q9H9J2
QPEPIKVYGQVSLND	SORL1	86	Q92673
FNGVKVLPIPVLSDN	PNKD	116	Q8N490
APDVKPVQNGSQLFI	PHF2	76	O75151
NFFVEKNPTIVNFPI	USP39	461	Q53GS9
EQVQSGKLIPFSPAV	SVIL	861	O95425
FPPQLVVQKGLVAIQ	LRRC27	151	Q9C0I9
VVPAFRSLQKQVGTP	AATK	886	Q6ZMQ8
QVQVSTPVLEVKNPF	SAMD3	426	Q8N6K7
QGLPVVPKNVAFVID	ITIH3	276	Q06033
NDGPNPVVQIIYSDK	FNTA	81	P49354
PKKIQFAVPVFQSQI	PPP1R1C	6	Q8WVI7
EELQIYQQGPKSPSV	NICN1	131	Q9BSH3
DPQTPLVFKGVVFNE	PITRM1	191	Q5JRX3
SFPEEPSQVQLKGVQ	PKHD1	2191	P08F94
TALFGQPPFKNVIVN	IARS1	576	P41252
QPPFKNVIVNGLVLA	IARS1	581	P41252
DKAVVPVFNPVRSQT	PGBD1	201	Q96JS3
PPAIKDAVITGNNFT	SVEP1	1966	Q4LDE5
SEVFVPDLVNGPTNK	EXO1	456	Q9UQ84
KFIQSSGQPVPLVVE	ARHGAP4	511	P98171
QIFLNRNPGVPSVVK	RPTOR	1016	Q8N122
PQEVTLKPGNGTVFV	ROBO4	351	Q8WZ75
QTKPVVTPFGQVAAA	AGFG1	521	P52594
IEVGQPAAGNQPFVK	CLTCL1	231	P53675
PAAGNQPFVKKAVDV	CLTCL1	236	P53675
SVPQQQVFGLAEPKR	SPATA13	621	Q96N96
PPTQRLTFKEVFENG	PPP3CC	21	P48454
DDQKIQVTPPGFQLV	XRCC6	421	P12956
VVTNKQAAPGFIGPQ	USP42	441	Q9H9J4
DIVPVKENFNPTTGI	VSIG1	181	Q86XK7
PFQKGFIIQPDSSIV	RREB1	441	Q92766
QVEPNTKVFPAVFLQ	RYR3	1436	Q15413
VPRNKNPFQEAIVFV	SCFD1	581	Q8WVM8
TAEVEKPAGLLFQQP	TACC2	2731	O95359
KQLGIPTANFPEQVV	RFK	21	Q969G6
KPNEGVIIIGATNFP	YME1L1	471	Q96TA2
EFSFNTPGKNVNPVI	SLC30A6	386	Q6NXT4
AQFPLQPGKVATFTI	TRAPPC9	776	Q96Q05
NGEVFQKPFVEKPVS	PPIP5K2	176	O43314
NITSPVINVPLKVFF	TMEM41B	216	Q5BJD5
LQVVVQEPGQVFKPF	XPO6	896	Q96QU8
NVPEPILQKLVAAFG	VWA8	946	A3KMH1
QVAASPAVGQPLQKE	TOPBP1	801	Q92547
LFQPFGKVNDVLIVP	ZNF638	696	Q14966
TGLPAAQVQEPVTFK	ZNF606	51	Q8WXB4
PNGIFPQLFQSTIKD	UNC79	2091	Q9P2D8
QQVTLPAIPSKGVFL	ZAN	1236	Q9Y493
KPDGISFENRVPQVA	WNK3	16	Q9BYP7
QVGVPDCRIFTVNPK	LPIN2	821	Q92539