Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	4 iron, 4 sulfur cluster binding	RTEL1 POLD1 DDX11 CDK5RAP1 DDX11L8	4.20e-05	47	165	5	GO:0051539
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	PADI4 ARG1 PADI3	8.71e-05	11	165	3	GO:0016813
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	RTEL1 POLD1 UPF1 METTL4 TERT DDX11 LIG3 N4BP2 DDX11L8	3.40e-04	262	165	9	GO:0140097
GeneOntologyMolecularFunction	triplex DNA binding	DDX11 DDX11L8	4.03e-04	4	165	2	GO:0045142
GeneOntologyMolecularFunction	iron-sulfur cluster binding	RTEL1 POLD1 DDX11 CDK5RAP1 DDX11L8	4.71e-04	78	165	5	GO:0051536
GeneOntologyMolecularFunction	pyrophosphatase activity	DNAH3 REM1 ATP7A RTEL1 NAIP NUDT16L1 UPF1 DRG1 SEPTIN2 DDX11 ATP11B DDX50 ERAS DNM3 KIF13A DDX11L8 ATP5F1A	5.97e-04	839	165	17	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DNAH3 REM1 ATP7A RTEL1 NAIP NUDT16L1 UPF1 DRG1 SEPTIN2 DDX11 ATP11B DDX50 ERAS DNM3 KIF13A DDX11L8 ATP5F1A	6.05e-04	840	165	17	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DNAH3 REM1 ATP7A RTEL1 NAIP NUDT16L1 UPF1 DRG1 SEPTIN2 DDX11 ATP11B DDX50 ERAS DNM3 KIF13A DDX11L8 ATP5F1A	6.05e-04	840	165	17	GO:0016818
GeneOntologyMolecularFunction	metal cluster binding	RTEL1 POLD1 DDX11 CDK5RAP1 DDX11L8	6.26e-04	83	165	5	GO:0051540
GeneOntologyMolecularFunction	protein-arginine deiminase activity	PADI4 PADI3	6.68e-04	5	165	2	GO:0004668
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DNAH3 REM1 ATP7A RTEL1 NAIP UPF1 DRG1 SEPTIN2 DDX11 ATP11B DDX50 ERAS DNM3 KIF13A DDX11L8 ATP5F1A	7.11e-04	775	165	16	GO:0017111
Domain	P-loop_NTPase	DNHD1 MAGI1 DNAH3 REM1 RTEL1 NAIP LRRK1 UPF1 DRG1 EHD2 SEPTIN2 DDX11 MAGI2 NWD2 CTPS2 ADSS2 DDX50 N4BP2 ERAS DNM3 KIF13A ATP5F1A MPP7	1.83e-06	848	166	23	IPR027417
Domain	-	DNHD1 DNAH3 REM1 RTEL1 NAIP LRRK1 UPF1 DRG1 EHD2 SEPTIN2 DDX11 NWD2 CTPS2 DDX50 N4BP2 ERAS DNM3 ATP5F1A MPP7	3.68e-05	746	166	19	3.40.50.300
Domain	Cupredoxin	PADI4 F5 PKHD1L1 PADI3	3.89e-05	22	166	4	IPR008972
Domain	Guanylate_kinase_CS	MAGI1 MAGI2 MPP7	3.55e-04	16	166	3	IPR020590
Domain	Helicase_C_2	RTEL1 DDX11	4.66e-04	4	166	2	PF13307
Domain	DEAD_2	RTEL1 DDX11	4.66e-04	4	166	2	PF06733
Domain	DEAD_2	RTEL1 DDX11	4.66e-04	4	166	2	IPR010614
Domain	ATP-dep_Helicase_C	RTEL1 DDX11	4.66e-04	4	166	2	IPR006555
Domain	Helicase-like_DEXD_c2	RTEL1 DDX11	4.66e-04	4	166	2	IPR006554
Domain	DNA_helicase_DNA-repair_Rad3	RTEL1 DDX11	4.66e-04	4	166	2	IPR013020
Domain	SPOC	RBM15 SPOCD1	4.66e-04	4	166	2	PS50917
Domain	HELICASE_ATP_BIND_2	RTEL1 DDX11	4.66e-04	4	166	2	PS51193
Domain	GPR107-like	TMEM87A TMEM87B	4.66e-04	4	166	2	IPR009637
Domain	Lung_7-TM_R	TMEM87A TMEM87B	4.66e-04	4	166	2	PF06814
Domain	Helic_SF1/SF2_ATP-bd_DinG/Rad3	RTEL1 DDX11	4.66e-04	4	166	2	IPR014013
Domain	DEXDc2	RTEL1 DDX11	4.66e-04	4	166	2	SM00488
Domain	HELICc2	RTEL1 DDX11	4.66e-04	4	166	2	SM00491
Domain	Cadherin_C	PCDHGB5 PCDHGB1 PCDHB6 PCDHB1	5.18e-04	42	166	4	IPR032455
Domain	Cadherin_C_2	PCDHGB5 PCDHGB1 PCDHB6 PCDHB1	5.18e-04	42	166	4	PF16492
Domain	CADHERIN_1	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.19e-04	113	166	6	PS00232
Domain	Cadherin	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.19e-04	113	166	6	PF00028
Domain	CADHERIN_2	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.44e-04	114	166	6	PS50268
Domain	-	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.44e-04	114	166	6	2.60.40.60
Domain	CA	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.70e-04	115	166	6	SM00112
Domain	Cadherin-like	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	5.97e-04	116	166	6	IPR015919
Domain	Cadherin	PCDHGB5 PCDHGB1 CDHR3 PCDHB6 DSG4 PCDHB1	6.53e-04	118	166	6	IPR002126
Domain	PAD	PADI4 PADI3	7.72e-04	5	166	2	PF03068
Domain	PAD_N	PADI4 PADI3	7.72e-04	5	166	2	PF08526
Domain	PAD_M	PADI4 PADI3	7.72e-04	5	166	2	PF08527
Domain	PAD	PADI4 PADI3	7.72e-04	5	166	2	IPR004303
Domain	PAD_C	PADI4 PADI3	7.72e-04	5	166	2	IPR013530
Domain	Prot_Arg_deaminase_cen_dom	PADI4 PADI3	7.72e-04	5	166	2	IPR013733
Domain	PAD_N	PADI4 PADI3	7.72e-04	5	166	2	IPR013732
Domain	GUANYLATE_KINASE_2	MAGI1 MAGI2 MPP7	1.07e-03	23	166	3	PS50052
Domain	GUANYLATE_KINASE_1	MAGI1 MAGI2 MPP7	1.07e-03	23	166	3	PS00856
Domain	SPOC_C	RBM15 SPOCD1	1.15e-03	6	166	2	IPR012921
Domain	SPOC	RBM15 SPOCD1	1.15e-03	6	166	2	PF07744
Domain	Guanylate_kin	MAGI1 MAGI2 MPP7	1.54e-03	26	166	3	PF00625
Domain	GK/Ca_channel_bsu	MAGI1 MAGI2 MPP7	1.54e-03	26	166	3	IPR008145
Domain	Guanylate_kin-like_dom	MAGI1 MAGI2 MPP7	1.54e-03	26	166	3	IPR008144
Domain	GuKc	MAGI1 MAGI2 MPP7	1.54e-03	26	166	3	SM00072
Domain	KOW	RPS4Y2 RPL27	1.60e-03	7	166	2	SM00739
Domain	TrpB-like_PLP-dep	SDSL THNSL2	1.60e-03	7	166	2	IPR001926
Domain	PALP	SDSL THNSL2	1.60e-03	7	166	2	PF00291
Domain	PDZ	MAGI1 MAGI2 SNX27 GRIP2 MPP7 PDZD2	1.64e-03	141	166	6	PF00595
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RPL27 RBM15 CAND1 ACACB MRPS12 FBL ACLY POLD1 UBR4 KDM3B NUDT16L1 UPF1 TERT ACTR2 DRG1 POLR1F SNIP1 ESYT2 EEF1D DDX50 SLC25A1 SLC25A10 IQSEC1 TSPO SNRPA1 RPL3 ATP5F1A	2.68e-10	1318	169	27	30463901
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	RPS4Y2 RPL27 RBM15 ATP7A FBL SCYL1 ARFGEF1 ITGA5 TMEM87A ACTR2 PIKFYVE ESYT2 RNF5 WDR6 TMEM87B SLC25A1 SLC25A10 TMF1 RPL3 GPAT4 PLXNA1 ATP5F1A	1.61e-09	952	169	22	38569033
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL27 RBM15 CAND1 FBL ACLY POLD1 UBR4 POLRMT UPF1 DUS3L ARG1 POLR1F LIG3 EEF1D ADSS2 DDX50 WDR6 SLC25A1 A2ML1 LTN1 IQSEC1 SNX27 WDFY3 SNRPA1 RPL3 ATP5F1A	2.27e-09	1353	169	26	29467282
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 RPL27 RBM15 CAND1 MAT2B FBL ACLY POLD1 UBR4 POLRMT UPF1 TESK1 ACTR2 DRG1 SEPTIN2 LIG3 EEF1D ADSS2 DDX50 WDR6 CD47 PNPLA8 SNRPA1 RPL3 PLXNA1 ATP5F1A	6.59e-09	1425	169	26	30948266
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	KPNA5 RPL27 RBM15 CAND1 FBL ACLY POLD1 UBR4 TSC2 UPF1 ACTR2 DRG1 DDX11 ESYT2 EEF1D CTPS2 WDR6 AASS SLC25A1 AGL SLC25A10 RPL3 GPAT4 ATP5F1A	1.14e-08	1257	169	24	37317656
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	FNIP2 KPNA5 ATP7A ARFGEF1 TSC2 ITGA5 TMEM87A DENND4C PIKFYVE ESYT2 VAC14 WDR6 TMF1 GPAT4 PLXNA1	2.92e-08	504	169	15	34432599
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CAND1 POLD1 UBR4 POLRMT LAMB1 GBE1 TSC2 UPF1 TUBGCP4 ACTR2 CCNB1 EHD2 GGH LIG3 ESYT2 EEF1D ADSS2 DDX50 WDR6 AASS LTN1 SNRPA1 SNX9 ATP5F1A	1.44e-07	1440	169	24	30833792
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPS12 FBL UBR4 POLRMT SCYL1 TSC2 NUDT16L1 UPF1 ACTR2 ARAF CCNB1 PIKFYVE SNIP1 ESYT2 DDX50 UQCC3 WDR6 AASS CDK5RAP1 PNPLA8 DDHD2 RPL3 GPAT4 ATP5F1A	2.87e-07	1496	169	24	32877691
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	KPNA5 CAND1 ACLY POLD1 UBR4 POLRMT LAMB1 PTPRU ARAF CCNB1 ESYT2 WDR6 AGL LTN1 SNX27 STYXL1 SNRPA1 RPL3 MPP7	3.12e-07	974	169	19	28675297
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	RPL27 DNAH3 EPHA6 FBL ACLY SCYL1 GBE1 UPF1 ACTR2 DRG1 SEPTIN2 ARG1 EEF1D TSPO RPL3 DCLK1 ATP5F1A	4.44e-07	803	169	17	36517590
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SDSL EPPK1 MRPS12 UBR4 POLRMT KDM3B TSC2 LRRK1 ITGA5 TESK1 ARSG TPCN1 PIKFYVE VAC14 FGFR2 WDFY3 RGL2 GPAT4 ADAT1 PLXNA1	4.86e-07	1105	169	20	35748872
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	UBR4 ACAD10 UPF1 ACTR3B TUBGCP4 F5 SEPTIN2 NWD2 WDR6 A2ML1 SNX27 SNRPA1 RPL3	6.50e-07	475	169	13	31040226
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	RPL27 CAND1 FBL ACLY UBR4 ARFGEF1 LAMB1 TUBGCP4 ACTR2 ESYT2 SLC25A1 LTN1 SNRPA1 RPL3 ATP5F1A	8.62e-07	657	169	15	36180527
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RPL27 RBM15 EPPK1 FBL ACLY POLRMT ABT1 UPF1 F5 ACTR2 DRG1 SEPTIN2 ARG1 EEF1D DDX50 WDR6 SLC25A1 KCTD20 SNRPA1 RPL3 ATP5F1A	8.96e-07	1257	169	21	36526897
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 RPL27 RBM15 KDM3B TSC2 TESK1 ARAF DENND4C POLR1F ESYT2 AASS N4BP2 SLC25A1 IQSEC1 KIF13A RGL2 DCLK1	1.15e-06	861	169	17	36931259
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	RPL27 EPPK1 CAND1 ACLY UBR4 POLRMT KDM3B LAMB1 GBE1 ITGA5 ACTR2 CCNB1 DRG1 GGH EEF1D DDX50 WDR6 SLC25A10 TSPO RPL3 ATP5F1A	1.47e-06	1297	169	21	33545068
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	CAND1 FBL ACLY UBR4 UPF1 ITGA5 ACTR2 DRG1 SEPTIN2 ESYT2 EEF1D SLC25A1 SNRPA1 RPL3 ATP5F1A	2.13e-06	707	169	15	19738201
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAGI1 RPL27 ATP7A ACLY UPF1 THSD1 DENND4C SEPTIN2 ESYT2 ADSS2 SNRPA1 SNX9 RPL3 ATP5F1A MPP7	2.16e-06	708	169	15	39231216
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	RPL27 EPPK1 CAND1 ACLY UBR4 TMEM14C UPF1 TMEM200A ACTR2 SEPTIN2 EEF1D ADSS2 SLC25A1 SLC25A10 RPL3 ATP5F1A	2.29e-06	807	169	16	30575818
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	RPL27 CAND1 MAT2B FBL ACLY POLRMT UPF1 ACTR3B DUS3L ACTR2 CCNB1 DRG1 EEF1D LSM6 CTPS2 WDR6 WDR87 SNRPA1 SNX9 RPL3 ATP5F1A	2.32e-06	1335	169	21	29229926
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	RPL27 EPPK1 UBR4 GBE1 UPF1 DRG1 EEF1D VAC14 GPT2 SNX9	2.64e-06	304	169	10	32235678
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM15 EPPK1 CAND1 GAS2L3 FBL ACLY NUDT16L1 F5 ACTR2 DRG1 ARG1 LIG3 EEF1D DDX50 SNRPA1 SNX9 RPL3 ATP5F1A	2.83e-06	1024	169	18	24711643
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	RPL27 CAND1 FBL ACLY UPF1 EEF1D WDR6 SLC25A1 SNRPA1 RPL3 ATP5F1A	3.06e-06	383	169	11	29331416
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MAGI1 RPL27 RBM15 CAND1 FBL ACLY POLD1 LAMB1 UPF1 TUBGCP4 ACTR2 ARAF LIG3 EEF1D ADSS2 WDR87 SLC25A1 GPT2 RPL3 ATP5F1A	3.08e-06	1247	169	20	27684187
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	RBM15 POLD1 UBR4 TSC2 ESYT2 ATP11B DDX50 WDR6 LTN1 KCTD20	3.42e-06	313	169	10	38270169
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RPL27 EPPK1 CAND1 ACLY POLD1 UBR4 UPF1 ACTR2 DRG1 SEPTIN2 PHKA2 LIG3 EEF1D VAC14 AGL SNRPA1 SNX9 RPL3 ATP5F1A	3.57e-06	1149	169	19	35446349
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	SDSL SLC25A41 ACACB MAT2B MRPS12 ACLY TMEM14C POLRMT ACAD10 CRLS1 CTPS2 AASS SLC25A1 DHODH SLC25A10 TSPO GPT2 ATP5F1A	3.85e-06	1047	169	18	18614015
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	KPNA5 RPL27 EPPK1 MAT2B FBL UBR4 NUDT16L1 ACTR3B ARG1 GGH EEF1D SLC25A1 SNRPA1 SNX9 RPL3 ATP5F1A	4.05e-06	844	169	16	25963833
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	RBM15 CAND1 ACLY SCYL1 UPF1 DUS3L DRG1 SEPTIN2 ESYT2 EEF1D VAC14 DDX50 SLC25A10 SNX9	4.18e-06	653	169	14	33742100
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MAGI1 EPPK1 FBL ACLY POLD1 UBR4 TSC2 LRRK1 ACTR3B ACTR2 ARAF SEPTIN2 MAGI2 LIG3 EEF1D VAC14 SLC25A1 STYXL1 SNRPA1 RPL3	4.75e-06	1284	169	20	17353931
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	CAND1 FBL ACLY NUDT16L1 UPF1 EEF1D WDR6 SLC25A1 SLC25A10 CD47 RPL3 ATP5F1A	4.88e-06	484	169	12	31995728
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	RPL27 CAND1 FBL ACLY ARFGEF1 LRRK1 UPF1 SEPTIN2 EEF1D AGL SNX9 RPL3	5.99e-06	494	169	12	26831064
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RPL27 RBM15 CAND1 MRPS12 NUDT16L1 UPF1 DRG1 ARG1 GGH LIG3 NWD2 DDX50 SLC25A1 SLC25A10 IQSEC1 DNM3 SNRPA1 TNXB	6.04e-06	1082	169	18	38697112
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	RPS4Y2 CAND1 FBL ACLY POLD1 POLRMT SLC25A1 RPL3 ATP5F1A	8.05e-06	272	169	9	25315684
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	RPS4Y2 RPL27 ACLY LAMB1 GBE1 ACAD10 ACTR2 EHD2 GGH MAGI2 SNIP1 ESYT2 CRLS1 CLCN5 SLC25A10 IQSEC1 SNRPA1 GPT2 RPL3 PLXNA1 ATP5F1A	8.32e-06	1451	169	21	30550785
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	NAIP POLRMT LAMB1 TSC2 NUDT16L1 DUS3L CCNB1 DRG1 EEF1D	1.04e-05	281	169	9	24163370
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RPL27 RBM15 MRPS12 FBL POLRMT NUDT16L1 UPF1 DRG1 SNIP1 DDX50 LTN1 CDK5RAP1 SNRPA1 RPL3	1.13e-05	713	169	14	29802200
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	MRPS12 PYROXD2 TMEM14C POLRMT ACAD10 LIG3 CRLS1 CTPS2 UQCC3 AASS SLC25A1 DHODH SLC25A10 TSPO CDK5RAP1 PNPLA8 GPT2 ATP5F1A	1.17e-05	1136	169	18	34800366
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	RPL27 EPPK1 CAND1 FBL UBR4 KDM3B ARFGEF1 UPF1 DRG1 SEPTIN2 ARG1 ESYT2 EEF1D ADSS2 SLC25A1 AGL A2ML1 SLC25A10 SNRPA1 ATP5F1A	1.19e-05	1367	169	20	32687490
Pubmed	MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.	CAND1 MAT2B NUDT16L1 ACTR2 DRG1 SEPTIN2 EEF1D SNRPA1 ATP5F1A	1.24e-05	287	169	9	36180891
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ATP7A ABT1 NUDT16L1 UPF1 TMEM87A DENND4C ATP11B CLCN5 WDR6 SLC25A10 CDK5RAP1 TMF1 KIF13A SNX9	1.24e-05	719	169	14	35337019
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	POLD1 TSC2 PTPRU TERT ARSG EEF1D VAC14 HSPA12A AASS AGL STYXL1 KIF13A SPOCD1 RPL3 ADAT1 ATP5F1A	1.27e-05	925	169	16	28986522
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	SDSL ACACB MAT2B MRPS12 ACLY TMEM14C POLRMT ACAD10 CRLS1 AASS SLC25A1 DHODH SLC25A10 TSPO GPT2 ATP5F1A	1.28e-05	926	169	16	20877624
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	RPL27 CAND1 POLD1 UPF1 ACTR2 DRG1 ESYT2 WDR6 SLC25A1 SLC25A10 SNRPA1 SNX9 RPL3 ATP5F1A	1.36e-05	725	169	14	27025967
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	FBL POLD1 SCYL1 KDM3B UPF1 ACTR3B ACTR2 ARAF DENND4C CCNB1 DRG1 SEPTIN2 VAC14 CTPS2 KCTD20 IQSEC1 SNRPA1	1.36e-05	1038	169	17	26673895
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	UBR4 POLRMT UPF1 ESYT2 DDX50 SLC25A1 SLC25A10 RPL3	1.36e-05	221	169	8	29991511
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	RPL27 RBM15 FBL ACLY UPF1 DRG1 ARG1 EEF1D SLC25A1 TSPO SNX27 RPL3 ATP5F1A	1.67e-05	641	169	13	36057605
Pubmed	Defining the membrane proteome of NK cells.	RPL27 CAND1 ATP7A ACLY POLD1 UBR4 SCYL1 TUBGCP4 F5 ACTR2 DRG1 ESYT2 ATP11B CLCN5 DDX50 IQSEC1 GPAT4 ATP5F1A	1.69e-05	1168	169	18	19946888
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RPL27 RBM15 EPPK1 MRPS12 FBL ACLY ABT1 UPF1 ACTR2 ARG1 SNIP1 EEF1D DDX50 SLC25A1 RPL3 ATP5F1A	1.73e-05	949	169	16	36574265
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	RPL27 UBR4 TSC2 UPF1 TUBGCP4 DDX50 SNRPA1 RPL3 ATP5F1A	1.75e-05	300	169	9	28561026
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	KPNA5 EPPK1 ACLY UBR4 UPF1 ACTR3B ESYT2 RNF5 SLC25A10 LTN1 SNX27 RPL3 ATP5F1A	1.84e-05	647	169	13	26618866
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	RPL27 FBL ACLY UPF1 DRG1 SEPTIN2 LSM6 SLC25A1 SNRPA1 RPL3 ATP5F1A	2.04e-05	469	169	11	37314180
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 RBM15 ACACB ACLY TERT EEF1D DDX50 KIF13A	2.05e-05	234	169	8	36243803
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	RPL27 CAND1 FBL ACTR2 ARAF IGHV3-64D ESYT2 CTPS2 WDR6 SLC25A1 SLC25A10 ATP5F1A	2.27e-05	565	169	12	33567341
Pubmed	DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.	FBL ABT1 ARG1 GGH SLC25A1 DSG4 SNRPA1 ATP5F1A	2.32e-05	238	169	8	35864588
Pubmed	The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1.	TSC2 CCNB1	2.35e-05	2	169	2	21900748
Pubmed	ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.	PIKFYVE VAC14	2.35e-05	2	169	2	17475247
Pubmed	A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.	PIKFYVE VAC14	2.35e-05	2	169	2	15542851
Pubmed	Identification of an Electrogenic 2Cl-/H+ Exchanger, ClC5, as a Chloride-Secreting Transporter Candidate in Kidney Cyst Epithelium in Tuberous Sclerosis.	TSC2 CLCN5	2.35e-05	2	169	2	36336066
Pubmed	RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population.	RTEL1 TERT	2.35e-05	2	169	2	23812731
Pubmed	Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.	MAGI1 MAGI2	2.35e-05	2	169	2	23523645
Pubmed	Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.	TMEM87A TMEM87B	2.35e-05	2	169	2	26157166
Pubmed	The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling.	TSC2 CCNB1	2.35e-05	2	169	2	30629673
Pubmed	Association of cross-reactive antibodies targeting peptidyl-arginine deiminase 3 and 4 with rheumatoid arthritis-associated interstitial lung disease.	PADI4 PADI3	2.35e-05	2	169	2	24901704
Pubmed	Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.	GRIN3A GRIN3B	2.35e-05	2	169	2	11735224
Pubmed	Physical Interaction between Embryonic Stem Cell-Expressed Ras (ERas) and Arginase-1 in Quiescent Hepatic Stellate Cells.	ARG1 ERAS	2.35e-05	2	169	2	35159317
Pubmed	MAGI1 copy number variation in bipolar affective disorder and schizophrenia.	MAGI1 MAGI2	2.35e-05	2	169	2	22381734
Pubmed	Genetic variation in N-methyl-D-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease.	GRIN3A GRIN3B	2.35e-05	2	169	2	20016182
Pubmed	New Insights into Behçet's Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation.	ACLY SLC25A1	2.35e-05	2	169	2	30050389
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MAT2B MRPS12 ACLY ARFGEF1 LAMB1 TSC2 ITGA5 TMEM87A DRG1 TPCN1 GGH EEF1D VAC14 LTN1 CD47 C1QTNF6 GPAT4 PLXNA1	2.44e-05	1201	169	18	35696571
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	MAGI1 MAGI2 SNX27 PDZD2	2.50e-05	35	169	4	33864728
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RPL27 CAND1 MAT2B ACLY POLD1 UBR4 SCYL1 KDM3B LAMB1 DUS3L ACTR2 SEPTIN2 GGH EEF1D CTPS2 ADSS2 AGL SNRPA1 KIF13A RPL3	2.89e-05	1455	169	20	22863883
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	CAND1 ACLY UPF1 ACTR2 SEPTIN2 DNM3 SNRPA1	3.01e-05	180	169	7	30110629
Pubmed	Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.	RPS4Y2 RPL27 EPPK1 CAND1 RPL3 ATP5F1A	3.06e-05	122	169	6	29530978
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	RPL27 EPPK1 FBL POLD1 CCNB1 LIG3 DDX50 SLC25A1 SLC25A10 SNX9 DCLK1 ATP5F1A	3.08e-05	583	169	12	29844126
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	RPL27 FBL UBR4 TUBGCP4 ESYT2 SLC25A1 LTN1 SNRPA1 RPL3 ATP5F1A	3.38e-05	408	169	10	33766124
Pubmed	Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.	CAND1 POLRMT DDX50 SLC25A1 SLC25A10 LTN1	3.50e-05	125	169	6	36030824
Pubmed	Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.	RPS4Y2 FBL ACLY LIG3 EEF1D N4BP2 KCTD20 RPL3 ATP5F1A	3.87e-05	332	169	9	30595499
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	EPPK1 ACLY DENND4C EEF1D SNX27 SNRPA1 RPL3 MPP7	3.89e-05	256	169	8	33397691
Pubmed	Nucleolar proteome dynamics.	RPL27 FBL KDM3B ABT1 NUDT16L1 CCNB1 SEPTIN2 DDX50 SNRPA1 RPL3	4.22e-05	419	169	10	15635413
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RPL27 RBM15 EPPK1 MRPS12 FBL POLRMT ABT1 NUDT16L1 UPF1 DUS3L LSM6 DDX50 SNRPA1 RPL3	4.37e-05	807	169	14	22681889
Pubmed	Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.	RPL27 FBL NUDT16L1 UPF1 DRG1 WDR87 TMF1 SNX9 RPL3 ATP5F1A	4.39e-05	421	169	10	34650049
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	CAND1 ACLY POLD1 ABT1 UPF1 DRG1 DDX50 SNRPA1 RPL3 ATP5F1A	4.76e-05	425	169	10	21081503
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	EPHA6 CYP2E1 POLD1 CDHR3 PYROXD2 TSC2 ACTR3B PKHD1L1 MAGI2 ADSS2 GRIN3A DCLK1 MPP7 PDZD2	4.79e-05	814	169	14	23251661
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	MAGI1 MAGI2 PDZD2	4.91e-05	15	169	3	23782696
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	CAND1 MAT2B UBR4 GBE1 UPF1 ITGA5 SEPTIN2 GGH SNX27	5.09e-05	344	169	9	30333137
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RPS4Y2 CAND1 FBL ACLY GGH ESYT2 SLC25A1 RPL3 ATP5F1A	5.09e-05	344	169	9	36282215
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	CAND1 ACLY UPF1 ARAF WDR6 SLC25A1 RPL3	5.34e-05	197	169	7	31620119
Pubmed	Proteomic characterization of the human sperm nucleus.	RPL27 CAND1 MAT2B APCS ARG1 GGH EEF1D SLC25A1 SLC25A10 RPL3	6.11e-05	438	169	10	21630459
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CAND1 ACLY UBR4 SCYL1 ARFGEF1 TSC2 UPF1 CCNB1 DRG1 ESYT2 VAC14 CTPS2 RNF5 SLC25A1 SNX9	6.11e-05	942	169	15	31073040
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RPL27 EPPK1 CAND1 MAT2B FBL ACLY POLD1 UBR4 TSC2 UPF1 DRG1 EEF1D CTPS2 SLC25A1 AGL SLC25A10 SNRPA1 RPL3 ATP5F1A	6.32e-05	1415	169	19	28515276
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RPL27 RBM15 FBL ABT1 UPF1 ARG1 SNIP1 LSM6 DDX50 SLC25A1 SNRPA1 RPL3 ATP5F1A	6.43e-05	731	169	13	29298432
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	RPL27 RBM15 FBL ACLY UPF1 LIG3 EEF1D DDX50 RPL3 ATP5F1A	6.47e-05	441	169	10	31239290
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR4 HSPA12A NWD2 WDFY3 DCLK1	6.84e-05	87	169	5	12465718
Pubmed	A protein interaction landscape of breast cancer.	SDSL EPPK1 CAND1 UBR4 POLRMT ACTR2 ARAF CCNB1 DRG1 DDX50 RGL2 RPL3	6.88e-05	634	169	12	34591612
Pubmed	APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex.	PIKFYVE VAC14	7.02e-05	3	169	2	26216398
Pubmed	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.	PIKFYVE VAC14	7.02e-05	3	169	2	19037259
Pubmed	The amount of citrullinated proteins in synovial tissue is related to serum anti-cyclic citrullinated peptide (anti-CCP) antibody levels.	PADI4 PADI3	7.02e-05	3	169	2	26255191
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX11 DDX11L8	7.02e-05	3	169	2	17611414
Pubmed	CCDC26, CDKN2BAS, RTEL1 and TERT Polymorphisms in pediatric brain tumor susceptibility.	RTEL1 TERT	7.02e-05	3	169	2	26014354
Interaction	RHOF interactions	EPPK1 CAND1 ATP7A FBL ITGA5 DENND4C EHD2 PIKFYVE LIG3 ESYT2 HSPA12A DDX50 UQCC3 WDR6 SLC25A1 SLC16A7 GPAT4 PLXNA1 MPP7	3.30e-06	673	167	19	int:RHOF
Cytoband	5q31	PCDHGB5 PCDHGB1 PCDHB6 KDM3B PCDHB1	7.05e-05	115	169	5	5q31
GeneFamily	PDZ domain containing	MAGI1 MAGI2 SNX27 GRIP2 MPP7 PDZD2	3.02e-04	152	108	6	1220
GeneFamily	Peptidyl arginine deiminases	PADI4 PADI3	3.49e-04	5	108	2	677
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI1 MAGI2 MPP7	4.88e-04	26	108	3	904
GeneFamily	Clustered protocadherins	PCDHGB5 PCDHGB1 PCDHB6 PCDHB1	5.81e-04	64	108	4	20
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN3A GRIN3B	7.28e-04	7	108	2	1201
Coexpression	GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP	CCNB1 TPCN1 DDX11 PHKA2 HSPA12A SLC25A10 TMF1 PLXNA1 PADI3	6.39e-06	200	169	9	M9594
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PADI4 EPHA6 NAIP APCS STEAP4 F5 ARG1 MAGI2	5.35e-07	184	169	8	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	severe-Myeloid-Immature_Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RPL27 PADI4 ARFGEF1 GBE1 ARG1 ADSS2 AGL TSPO	8.95e-07	197	169	8	9599319dd1f80c81356a8624131566cc76d77d7e
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PADI4 STEAP4 F5 ARG1 ATP11B IQSEC1 TSPO WDFY3	9.66e-07	199	169	8	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	COVID-19_Mild-PLT_2\|COVID-19_Mild / Disease Group and Platelet Clusters	DNHD1 SDSL CDHR3 TSC2 DUS3L F5 LIG3	4.49e-06	173	169	7	d11705e56b6b21eec963ea224717f27680c781ed
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	LVRN ACACB ACLY ADAMTS12 NWD2 GPT2 SLC16A7	5.83e-06	180	169	7	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IQANK1 MAT2B TMEM14C DUS3L TESK1 DDX11 SWI5	6.27e-06	182	169	7	3fddadb2ff75013ec6eeb415872667a6bae1da2d
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	LVRN ACACB ADAMTS12 HSPA12A CRLS1 NWD2 GPT2	6.50e-06	183	169	7	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	LVRN ACACB ADAMTS12 CRLS1 NWD2 GPT2 SLC16A7	6.50e-06	183	169	7	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	LVRN ACACB ACLY GBE1 ADAMTS12 NWD2 GPT2	7.75e-06	188	169	7	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	control-Myeloid-Immature_Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RPL27 PADI4 ARFGEF1 GBE1 ARG1 ADSS2 TSPO	8.89e-06	192	169	7	9f12b79d661ef0f57c2c924e8ecc24a46ea996d2
ToppCell	Control-Classical_Monocyte\|Control / Disease condition and Cell class	PADI4 NAIP STEAP4 F5 TPCN1 TSPO KIF13A	9.51e-06	194	169	7	9e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell	severe-Myeloid-Immature_Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PADI4 ARFGEF1 GBE1 ARG1 ADSS2 AGL TSPO	9.83e-06	195	169	7	becad890a420267ca41e98e61a8da343b51e1945
ToppCell	COVID-19_Severe-Neu_2\|World / 5 Neutrophil clusters in COVID-19 patients	RPL27 PADI4 ARFGEF1 ARG1 CRLS1 ADSS2 TSPO	1.02e-05	196	169	7	16359a56297f0558fc93fa52563cce0c53def167
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	REM1 EFS CDHR3 ITGA8 LAMB1 TMEM200A ARSG	1.02e-05	196	169	7	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGA8 LAMB1 ADAMTS12 MAGI2 AASS TNXB DCLK1	1.02e-05	196	169	7	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLC43A2 NAIP KDM3B ITGA5 KCTD20 TSPO SNX27	1.05e-05	197	169	7	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	COVID-19_Severe-Neu_2\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	RPL27 PADI4 ARFGEF1 ARG1 CRLS1 ADSS2 TSPO	1.05e-05	197	169	7	945f19475905cdedf232315eea1076ca0b753b67
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	PADI4 NAIP STEAP4 ITGA5 F5 TSPO KIF13A	1.09e-05	198	169	7	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PADI4 STEAP4 F5 ARG1 ATP11B TSPO WDFY3	1.16e-05	200	169	7	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLC43A2 PADI4 NAIP F5 SNX27 WDFY3 KIF13A	1.16e-05	200	169	7	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	RV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	EPHA6 CYP2F1 FBL LAMB1 PHF11 DCLK1	1.24e-05	134	169	6	8c4046ba1f85172915a112499e492c3efe8474c2
ToppCell	remission-multiplets\|World / disease stage, cell group and cell class	DNAH3 ARG1 MAB21L3 FGFR2 GRIN3B PCDHB1	1.72e-05	142	169	6	286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUBGCP4 F5 AASS PHF11 THNSL2 MPP7	3.04e-05	157	169	6	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	METTL4 MYZAP PKHD1L1 ADAMTS12 PADI3 MPP7	3.75e-05	163	169	6	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	CDHR3 GBE1 METTL4 POLR1F SNIP1 TMF1	4.59e-05	169	169	6	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	CDHR3 GBE1 METTL4 POLR1F SNIP1 TMF1	4.59e-05	169	169	6	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	CDHR3 GBE1 METTL4 POLR1F SNIP1 TMF1	4.59e-05	169	169	6	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL1 ACAD10 METTL4 TESK1 ARG1 TMEM87B	5.22e-05	173	169	6	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL1 ACAD10 METTL4 TESK1 ARG1 TMEM87B	5.22e-05	173	169	6	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LRRK1 ARSG CCNB1 PIKFYVE CLCN5 DHODH	5.39e-05	174	169	6	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ARSG CCNB1 PIKFYVE CLCN5 DHODH PDZD2	5.57e-05	175	169	6	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	LVRN STEAP4 ADAMTS12 C1QTNF6 TNXB DCLK1	5.75e-05	176	169	6	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAS2L3 GBE1 PTPRU TMEM200A NWD2 MPP7	5.75e-05	176	169	6	de746cdf2c777eec88cb03863e128e97ad6e8fb0
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	LVRN ACACB ADAMTS12 CRLS1 NWD2 GPT2	5.93e-05	177	169	6	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	LVRN ACACB ADAMTS12 CRLS1 NWD2 GPT2	6.12e-05	178	169	6	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAS2L3 PTPRU MYZAP KCNV1 NWD2 MPP7	6.31e-05	179	169	6	820289f14ecf165758529c236bb220bb1a744f02
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAS2L3 PTPRU MYZAP KCNV1 NWD2 MPP7	6.31e-05	179	169	6	e5f781d35449628a7f356d71e26231dd63482eec
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	REM1 STEAP4 IL1RL2 LGALS4 TNXB	6.83e-05	112	169	5	88fcd0dc12b5c00804381fb7dd59a6a2a9f37419
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-\|Striatum / BrainAtlas - Mouse McCarroll V32	REM1 STEAP4 IL1RL2 LGALS4 TNXB	6.83e-05	112	169	5	fd4cc5190626cb262aae0a7f04559b0e9757270e
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)\|Striatum / BrainAtlas - Mouse McCarroll V32	REM1 STEAP4 IL1RL2 LGALS4 TNXB	6.83e-05	112	169	5	d652e6fae433a6b56bf2a448fba2cf6c5e558905
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 TNXB MPP7	7.13e-05	183	169	6	764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 TNXB MPP7	7.13e-05	183	169	6	38a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBE1 ACAD10 F5 AGL GPT2 SLC16A7	7.13e-05	183	169	6	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_2\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ACACB PCDHGB5 EFS MFSD9 ACTR3B	7.13e-05	113	169	5	dc002185095590fc071b2f39259f8b87a757e174
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 MAGI1 MAB21L3 GRIP2 SLC16A7 MPP7	7.57e-05	185	169	6	9438097e94219c1db922b8507e3a29106d32a923
ToppCell	mild_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	TERT PKHD1L1 CCNB1 IGHV3-64D GGH WDR87	8.27e-05	188	169	6	9a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCell	mild-Myeloid-Immature_Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PADI4 GBE1 ARG1 ADSS2 AGL TSPO	8.52e-05	189	169	6	94dd5d4d815449feff7ce157fe7f8234f7c81422
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PADI4 NAIP STEAP4 ARG1 MAB21L3 WDFY3	8.52e-05	189	169	6	235c24eeab5139f5821fccd5c879d8787682f4ef
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 CD47 MPP7	8.77e-05	190	169	6	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EFS TMEM200A C1QTNF6 THNSL2 DCLK1 PDZD2	8.77e-05	190	169	6	81f8f2cddf4c51b879f315260cd1fca80355a371
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic-stroma-muscle\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EFS TMEM200A C1QTNF6 THNSL2 DCLK1 PDZD2	8.77e-05	190	169	6	20106e5213f6a7560554b8b4f84b23c5554ba975
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 CD47 MPP7	8.77e-05	190	169	6	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PADI4 ARFGEF1 ACTR2 ARG1 ADSS2 TSPO	8.77e-05	190	169	6	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	control-Myeloid-Immature_Neutrophils_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PADI4 ARFGEF1 GBE1 ARG1 ADSS2 TSPO	8.77e-05	190	169	6	38e83337c70c8734b63f8589ba59e0f98603f94c
ToppCell	10x5'v1-week_17-19-Mesenchymal_myocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EFS TMEM200A C1QTNF6 THNSL2 DCLK1 PDZD2	8.77e-05	190	169	6	877b544decf302e0d41be23dffa1861f79c70914
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ACACB F5 TMEM87A ARG1 AASS GPT2	9.29e-05	192	169	6	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LVRN LAMB1 ITGA5 C1QTNF6 TNXB DCLK1	9.29e-05	192	169	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 TNXB MPP7	9.29e-05	192	169	6	5388f3115ab285f3f3001af1d71543ed64b9e044
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBL EEF1D TSPO SNRPA1 RPL3 ATP5F1A	9.29e-05	192	169	6	42b821381fb995fc04589356fd81e8eeeb675757
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGA8 LAMB1 ADAMTS12 MAGI2 AASS TNXB	9.55e-05	193	169	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	REM1 TERT IL1RL2 ARG1 GPT2 PADI3	9.55e-05	193	169	6	df4afb4848eb9d7d8d39e5c612919663cbbb2514
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	REM1 TERT IL1RL2 ARG1 GPT2 PADI3	9.55e-05	193	169	6	ab36d684bde8fe77d11a5188425135328052c58b
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 THSD1 MYZAP PKHD1L1 TNXB MPP7	9.55e-05	193	169	6	ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL27 FBL EEF1D TSPO RPL3 ATP5F1A	9.55e-05	193	169	6	13282e849b11f48085f0840d112a06e896b32cd7
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGA8 LAMB1 ADAMTS12 MAGI2 AASS TNXB	9.83e-05	194	169	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 LAMB1 STEAP4 EHD2 FGFR2 TNXB	9.83e-05	194	169	6	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 LAMB1 STEAP4 EHD2 FGFR2 TNXB	9.83e-05	194	169	6	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 LAMB1 STEAP4 EHD2 FGFR2 TNXB	9.83e-05	194	169	6	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MPZ EPHA6 GAS2L3 HSPA12A A2ML1 DHODH	1.04e-04	196	169	6	efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 CYP2F1 EFS FGFR2 TNXB DCLK1	1.04e-04	196	169	6	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	Control_saline-Epithelial_alveolar-AT_2-AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	SDSL STEAP4 ACAD10 TMEM87A CD47 FGFR2	1.07e-04	197	169	6	f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TERT ARG1 WDR87 KLHL34	1.09e-04	65	169	4	acc541e5a0e4be5ddd5702f191185c5b405b8762
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TERT ARG1 WDR87 KLHL34	1.09e-04	65	169	4	b8ab40d75b4078123cdffec2f5326cff65f67578
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PADI4 EPPK1 ARFGEF1 ARG1 ADSS2 TSPO	1.10e-04	198	169	6	3bc05b8d97a7219af40db7a11aa271f02e74fca5
ToppCell	Multiple_Sclerosis\|World / Disease, Lineage and Cell Type	RPL27 MAT2B EEF1D ABRACL CD47 RPL3	1.10e-04	198	169	6	46728bb03f4b0d30ae9b62d984a6c2d00cfd370a
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	ITGA8 LAMB1 ADAMTS12 MAGI2 TNXB DCLK1	1.13e-04	199	169	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PADI4 EPPK1 ARFGEF1 ARG1 ADSS2 TSPO	1.13e-04	199	169	6	a1635a52318be0423f8e4fc03d971c28cd22b57e
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PADI4 ACTR2 ARG1 ATP11B TSPO WDFY3	1.13e-04	199	169	6	b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCell	COVID-19-COVID-19_Mild-Myeloid-Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	PADI4 STEAP4 F5 ARG1 MAB21L3 WDFY3	1.13e-04	199	169	6	9f6b6731186ef399f952a75879eba66fd8ed3494
ToppCell	3'_v3-bone_marrow-Myeloid_Monocytic-Classical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	SLC43A2 PADI4 NAIP F5 TSPO WDFY3	1.13e-04	199	169	6	93f25e8f22deb438c930c2e95e572dbd16503f71
ToppCell	Calu_3-uninfected\|Calu_3 / Cell line, Condition and Strain	RPL27 FBL EEF1D UQCC3 TSPO RPL3	1.16e-04	200	169	6	cb9b6a6b085ae0e19b450940c4ecd92406d8a2b3
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 LAMB1 NWD2 FGFR2 KIF13A PDZD2	1.16e-04	200	169	6	0f23e72649a274043bf23e0952a9b5707c516acf
ToppCell	MS-Multiple_Sclerosis\|MS / Disease, condition lineage and cell class	RPL27 MAT2B EEF1D ABRACL CD47 RPL3	1.16e-04	200	169	6	dc682a6d230932503565ee0e176b22577b5cf141
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte\|Megakaryo-cells / Lineage, cell class and subclass	RPL27 EEF1D ABRACL TSPO RPL3 ATP5F1A	1.16e-04	200	169	6	f36023bb369d17b8ec8724616737738e3df01987
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PADI4 ACTR2 ARG1 ATP11B TSPO WDFY3	1.16e-04	200	169	6	808571d74bb5c4d765ff13fc9393f88020d4e90d
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CYP2E1 PP2D1 PHF11 RGL2	1.19e-04	126	169	5	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	facs-Pancreas-Exocrine-24m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 SLC5A11 KCNV1 NWD2 PADI3	1.38e-04	130	169	5	8c81853c806e9a0d562e00dc5e00a8fc569a854c
ToppCell	facs-Pancreas-Exocrine-24m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 SLC5A11 KCNV1 NWD2 PADI3	1.38e-04	130	169	5	3041d20fe964d282d95c0312396f26bc93929056
ToppCell	facs-Pancreas-Exocrine-24m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 SLC5A11 KCNV1 NWD2 PADI3	1.38e-04	130	169	5	3b6a8eaef593db73c2fad2260b9f1e15950ccb70
ToppCell	RV-14._Fibroblast_III\|RV / Chamber and Cluster_Paper	EPHA6 CYP2F1 FBL PHF11 DCLK1	1.95e-04	140	169	5	b4fee8eb6bf855b364b00bda3f78e49d851bbca0
Disease	Glycogen Storage Disease Type III	GBE1 AGL	2.96e-05	2	161	2	C0017922
Disease	silicosis (biomarker_via_orthology)	RTEL1 TERT ARG1	5.55e-05	14	161	3	DOID:10325 (biomarker_via_orthology)
Disease	Crohn's disease (implicated_via_orthology)	EFS PIKFYVE	8.84e-05	3	161	2	DOID:8778 (implicated_via_orthology)
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX11 DDX11L8	8.84e-05	3	161	2	DOID:0060535 (implicated_via_orthology)
Disease	Glycogen storage disease	GBE1 PHKA2 AGL	1.02e-04	17	161	3	cv:C0017919
Disease	Glycogen Storage Disease	GBE1 PHKA2 AGL	4.24e-04	27	161	3	C0017919
Disease	Diffuse interstitial pulmonary fibrosis	RTEL1 TERT	4.37e-04	6	161	2	cv:C0085786
Disease	liver disease (biomarker_via_orthology)	CYP2E1 ARG1	6.10e-04	7	161	2	DOID:409 (biomarker_via_orthology)
Disease	osteopetrosis (implicated_via_orthology)	LRRK1 CLCN5	6.10e-04	7	161	2	DOID:13533 (implicated_via_orthology)
Disease	age at onset, glioblastoma multiforme	RTEL1 TERT	8.11e-04	8	161	2	EFO_0000519, EFO_0004847
Disease	glioblastoma multiforme	RTEL1 TERT	1.04e-03	9	161	2	EFO_0000519
Disease	Dyskeratosis congenita	RTEL1 TERT	1.04e-03	9	161	2	cv:C0265965
Disease	breast cancer, ovarian carcinoma	TERT ABHD8 FGFR2	1.08e-03	37	161	3	EFO_0001075, MONDO_0007254
Disease	Short Stature, CTCAE	KDM3B IQSEC1	1.29e-03	10	161	2	C2919142
Disease	HOYERAAL-HREIDARSSON SYNDROME	RTEL1 TERT	1.29e-03	10	161	2	C1846142
Disease	Short stature	KDM3B IQSEC1	1.29e-03	10	161	2	C0349588
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	F5 PIKFYVE	2.22e-03	13	161	2	EFO_0802114
Disease	Hepatic fibrosis	CYP2F1 ARG1 THNSL2	2.44e-03	49	161	3	HP_0001395
Disease	susceptibility to childhood ear infection measurement	MPZ EPHA6 CDHR3 IQSEC1 FGFR2	2.52e-03	171	161	5	EFO_0007904
Disease	Hamman-Rich syndrome	RTEL1 TERT	2.58e-03	14	161	2	C0085786
Disease	central nervous system cancer, glioblastoma multiforme	RTEL1 TERT	2.58e-03	14	161	2	EFO_0000326, EFO_0000519
Disease	immature platelet count	TERT ESYT2 KCTD20 DNM3	2.75e-03	106	161	4	EFO_0803544
Disease	Dyskeratosis Congenita	RTEL1 TERT	3.38e-03	16	161	2	C0265965
Disease	Abnormal behavior	KDM3B IQSEC1	3.38e-03	16	161	2	C0233514
Disease	Schizophrenia	MAGI1 CYP2E1 ITGA8 ACTR2 ADAMTS12 MAGI2 HSPA12A ADSS2 FGFR2 GRIN3A TNXB DCLK1	3.42e-03	883	161	12	C0036341
Disease	MAJOR AFFECTIVE DISORDER 2	MAGI1 MAGI2	3.81e-03	17	161	2	C1839839
Disease	Multiple congenital anomalies	POLD1 FGFR2	3.81e-03	17	161	2	C0000772
Disease	Usual Interstitial Pneumonia	RTEL1 TERT	4.76e-03	19	161	2	C4721509
Disease	Hamman-Rich Disease	RTEL1 TERT	4.76e-03	19	161	2	C4721508
Disease	Familial Idiopathic Pulmonary Fibrosis	RTEL1 TERT	5.27e-03	20	161	2	C4721952

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILPTGDGIYRVAKLI	NAIP	1241	Q13075
EYAVRGPIVLKAGEI	GPT2	61	Q8TD30
GLVKGKSDPYGIIRV	ESYT2	406	A0FGR8
LAQLIGTGVKPRYIS	ARFGEF1	1056	Q9Y6D6
VRRPLYKNVVLSGGS	ACTR3B	311	Q9P1U1
GKVVGTPEVLRVYIG	EHD2	241	Q9NZN4
IYAIFPSGGVVADKI	A2ML1	536	A8K2U0
RKVLVLGSGYISEPV	AASS	481	Q9UDR5
RKIVTYPGELLLQGV	ABRACL	56	Q9P1F3
IKIIRPLTVYGLEDA	ACAD10	866	Q6JQN1
GGAEYQAVLPEVRKV	ARSG	471	Q96EG1
RGGPIKNYVTLVSRL	DNHD1	736	Q96M86
GALERGVAPIKRQYL	DUS3L	21	Q96G46
PIKDVVLCYGIALGS	LVRN	821	Q6Q4G3
AFYKGLVPAGIRLIP	SLC25A10	251	Q9UBX3
SKLVPVGYGIRKLQI	EEF1D	231	P29692
VESYTLPDGRIIKVG	ACTR2	241	P61160
YVDIGLIPKGARDIR	ADAMTS12	716	P58397
YKGIRPAINVGLSVS	ATP5F1A	401	P25705
DGYTFVEVKPGRVLR	ABHD8	31	Q96I13
IAPGSAKVIDVYRTG	ADAT1	246	Q9BUB4
AKDIVYIGLRDVDPG	ARG1	171	P05089
LRKAIEAVSPGLYRV	ATP7A	331	Q04656
YKVVSPALRAVGNIV	KPNA5	311	O15131
LLGEKYGNIRIPGEV	NWD2	121	Q9ULI1
TRRIKVAGPNGYAIL	RBM15	846	Q96T37
GRQLPEYKAVVVGAS	ERAS	36	Q7Z444
TIFRGYLIPKGTVVV	CYP2E1	376	P05181
GPRRVVVLSGYQAVK	CYP2F1	71	P24903
LVPRSAEAGYLVTKV	PCDHB1	576	Q9Y5F3
GLTARRTIIIKGYVP	LGALS4	201	P56470
YPLGSIIVESGKRVG	LTN1	1656	O94822
GIPKIYVAANSGARI	ACACB	1821	O00763
VTVRGKEYPLGRILF	PADI4	416	Q9UM07
VLIGEYLQIKGATPR	FGFR2	86	P21802
VYSGSGLVLPARVKG	KLHL34	236	Q8N239
GAAVLRIPILYGEVE	MAT2B	176	Q9NZL9
VRVSGLPRYDVLGVI	MAGI1	76	Q96QZ7
VRLLLKRGTGQVPEY	MAGI2	1221	Q86UL8
TVPGVIRYKGAKIQL	DRG1	101	Q9Y295
EERFGVRPKVTGYLI	MFSD9	311	Q8NBP5
PVIVRLPLYAAIKSG	LRRK1	191	Q38SD2
ERGLKNIRIGIEGYP	KCTD20	311	Q7Z5Y7
GYRVITDKCPEGIIL	KCNJ6	156	P48051
AVTFPGIKLIYDAGV	SLC43A2	191	Q8N370
KGVQYLIERGFVPDT	IQSEC1	541	Q6DN90
LPQGVRTIYTIDGLK	DCLK1	101	O15075
QKITYRISGVGIDRP	DSG4	81	Q86SJ6
GHRIGEYLEKIIPLV	CAND1	246	Q86VP6
ENKLLPLRRGYVGVV	DNM3	221	Q9UQ16
GKLAVVVASYRRPGA	KCNV1	66	Q6PIU1
YVPVGVVKPITLAAR	PLXNA1	716	Q9UIW2
IYGVRTKPILEGAKQ	OR52B6	311	Q8NGF0
RAAEPGYLVTKVVAV	PCDHGB1	576	Q9Y5G3
VTGDGPLVIKRVYKG	PDZD2	2771	O15018
LVPGESVYGEKRVSI	FBL	111	P22087
EKYRLVVLVGPVGVG	MPP7	366	Q5T2T1
LDVGIGQVSVKYPRL	DDHD2	481	O94830
VDKLGLGSVVPVEYL	KDM3B	126	Q7LBC6
NKYGSRPVVIAGGLL	SLC16A7	81	O60669
ALKISGVIGPYRETV	LAMB1	1206	P07942
SYIPVRVAEKILFVG	TUBGCP4	266	Q9UGJ1
VRQAPGKGLEYVSAI	IGHV3-64D	56	A0A0J9YX35
AVIKVRRSPLTYGVG	HSPA12A	526	O43301
RAAEPGYLVTKVVAV	PCDHGB5	576	Q9Y5G0
VVANGKEYPLGRILI	PADI3	416	Q9ULW8
YRVLEAGKIGIFESP	DDX11	31	Q96FC9
GDVYLTVKLLLPGVI	LIG3	301	P49916
GKVAVYRARPVVTVD	ITGA8	476	P53708
LVTVPIKGLAGYREA	MAB21L3	71	Q8N8X9
HLRKEGRIYPDVIIG	MGAT4D	111	A6NG13
LLTVGKPFAIEGYGI	GRIN3A	861	Q8TCU5
IIGDGPIVRKEIEYR	PTPRU	311	Q92729
ITERAGYGGSVPKII	IL1RL2	216	Q9HB29
VDKAVVYRGRPIVSA	ITGA5	481	P08648
RARYGVIIVGNPKAL	UPF1	876	Q92900
RPTALAKILGVYRIG	PIKFYVE	1906	Q9Y2I7
ACGSKKRVVPGIVYL	ABT1	36	Q9ULW3
KIRVGYPELAEVLGR	ADAM30	261	Q9UKF2
GAEPSRAVGTVKVYL	ARAF	11	P10398
AVRPKYLLGREVTGN	CCNB1	186	P14635
YRVGTALPGKFKIVL	GBE1	636	Q04446
IRPYINITILKGDKG	C1QTNF6	86	Q9BXI9
VIGLGIEAYVKVPRN	DNAH3	1261	Q8TD57
VKYLESAGARVVPVR	GGH	61	Q92820
IVPAIFGVSFGIRKL	GPAT4	31	Q86UL3
ISLEVLVKDRPYGGQ	CDHR3	311	Q6ZTQ4
LLEIGRIVSRYGVEP	GAS2L3	161	Q86XJ1
ATRGLYVKAAEGPVL	FNIP2	836	Q9P278
PEIKTILSGFIIRGY	CLCN5	241	P51795
YRVLEAGKIGIFESP	DDX11L8	31	A8MPP1
IPFIKRAVAEGYGVI	FAM172A	181	Q8WUF8
LLKGRGVTYLFPIQV	DDX50	151	Q9BQ39
IGVLYEGKERLIPGC	DENND4C	101	Q5VZ89
AITVAATEPGKGYLR	ADGRF2	576	Q8IZF7
RATVLAVKGAALGYP	EFS	516	O43281
IGRPVVVKLNSGVDY	LSM6	16	P62312
ERPVGVLTSSVYGKR	C5orf49	91	A4QMS7
IVGAILFVPGEYSLK	CD47	191	Q08722
TVELKRYGGPLGITI	GRIP2	656	Q9C0E4
KPGKVVLVLAGRYSG	RPL27	6	P61353
PYRLDSKVKQIGGGI	POLRMT	1081	O00411
RVPYVIISAAKGVAA	POLD1	921	P28340
TRIGLAPVLGYLIIE	CRLS1	116	Q9UJA2
PYEGLILGRVQEKTA	METTL4	376	Q8N3J2
RGKNGIRLVPELYAV	PHKA2	361	P46019
YRVVLLGDPGVGKTS	REM1	81	O75628
RAAEPGYLVTKVVAV	PCDHB6	576	Q9Y5E3
TEIREVGPIERKGFY	EPHA6	171	Q9UF33
KVLGPYVDGLSQLAV	KIF13A	176	Q9H1H9
LLTVGKPFAIEGYGI	GRIN3B	761	O60391
GKGVAVKERIIPYLL	PNPLA8	396	Q9NP80
EILALIGYVDPVKGR	PNPLA8	426	Q9NP80
IGYVDPVKGRGIRIL	PNPLA8	431	Q9NP80
LGKALGNIARVVPYG	RTEL1	541	Q9NZ71
ALYNIVKVARGAVLP	VAC14	116	Q08AM6
GGVVPYLGTFLKDLV	RGL2	426	O15211
KGERGLVPTDYVEIL	SNX9	46	Q9Y5X1
ADGTVGRRVKPYIID	SNIP1	316	Q8TAD8
ISREKVVPLYGRGSQ	RNF5	71	Q99942
ADVVVVRGKIRLYSP	TMEM200A	46	Q86VY9
LRGYKIPVIENLGAT	SNRPA1	26	P09661
VTPLGIYLKARVEAG	SCYL1	96	Q96KG9
LGPTLYAEVGDIIKV	F5	86	P12259
GYVETPRGLRTFKTV	RPL3	91	P39023
GVVGPELYGRLKRAE	EPPK1	991	P58107
EGVRVLGPLADYLVV	DHODH	196	Q02127
KIDGKVRVDITYPAG	RPS4Y2	71	Q8TD47
TLLKVLPAGGISYVV	SLC25A41	346	Q8N5S1
QKGLEPGDIAVLVLY	SLC5A11	21	Q8WWX8
LAAGYIAQKIGLPIR	THNSL2	266	Q86YJ6
KYVIILDPAISIGRR	SI	421	P14410
VVKAYTTRVGIGAFP	ADSS2	296	P30520
VEVLLKLGADPRVYA	IQANK1	241	A8MXQ7
YAARKLGIPATIVLP	SDSL	81	Q96GA7
QDLPGVKLTVVRGKY	MRPS12	116	O15235
GIVRAIRDYQGPLKE	ACLY	356	P53396
GLRVRAQPGDYVLVK	CDK5RAP1	561	Q96SZ6
GAPVYVVRSGGLVKT	ATP11B	121	Q9Y2G3
IIGYVKAGSVPSLAA	TMEM14C	26	Q9P0S9
VIRGVTTKELYPEFG	SWI5	216	Q1ZZU3
GYALLVIVTPGERRK	UQCC3	21	Q6UW78
GLRVTAIKIDPYINI	CTPS2	31	Q9NRF8
ERRGDYLGKTVQVVP	CTPS2	101	Q9NRF8
DELSGKGYALVPIIV	TMF1	346	P82094
ALIGYLGVRTFVPKP	WDFY3	1386	Q8IZQ1
GKDLVPQAAIEYGRI	STYXL1	101	Q9Y6J8
TPLVKKGLRQGYFVE	APCS	131	P02743
EARGGLKPEYDAVVI	PYROXD2	26	Q8N2H3
GLVRVPLYTQKDRVG	NUDT16L1	141	Q9BRJ7
KPSLYIGVRGTVVRS	SPOCD1	601	Q6ZMY3
PEAYVTVVLKLLGRD	THSD1	211	Q9NS62
KLQGLIPGARYEVTV	TNXB	3811	P22105
YKGTVPRLGRVCLDV	SLC25A1	276	P53007
PRVVRIVKSESGYGF	SNX27	41	Q96L92
PGVIAAILQLYRGTK	STEAP4	261	Q687X5
YREGARKEPLAVVGS	TESK1	206	Q15569
AGIETKRILAPYVGG	PKHD1L1	2681	Q86WI1
ILSRNIKIVGEDYPG	PKHD1L1	3256	Q86WI1
LLGVPIAYDNIKVVG	POLR1F	86	Q3B726
AVPQSDGVRGIYKLL	PHF11	141	Q9UIL8
CVKRVGTITLGPEYG	WDR6	706	Q9NNW5
YGVELFLKVAGLGPV	TPCN1	486	Q9ULQ1
LVIIVSLGYGIVKPR	TMEM87B	301	Q96K49
RGVKLRLTVVDTPGY	SEPTIN2	91	Q15019
AARGVLPYVGNLITK	UBR4	4201	Q5T4S7
ILPVGIARYGILELA	WDR87	2836	Q6ZQQ6
KTFLRTLVRGVPEYG	TERT	881	O14746
EKAVVPLGLYTGQLA	TSPO	76	P30536
LVIIVSLGYGIVKPR	TMEM87A	311	Q8NBN3
PGYEVGQRKRLISSV	TSC2	1786	P49815
PYGLVEGQVKTTRGL	PP2D1	406	A8MPX8
KSGGGYIVVDPILRV	AGL	101	P35573
QGGVARIKPAVIKYL	N4BP2	1736	Q86UW6
VFEKVPTRYGVVLGA	MPZ	146	P25189
KLPQGVVYGVVRRSD	MYZAP	66	P0CAP1