Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucokinase activity	HK1 HKDC1	1.38e-04	5	75	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK1 HKDC1	1.38e-04	5	75	2	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HK1 HKDC1	1.38e-04	5	75	2	GO:0008865
Domain	TIL	VWF MUC5B MUC5AC OTOG	1.29e-07	12	77	4	PF01826
Domain	C8	VWF MUC5B MUC5AC OTOG	1.29e-07	12	77	4	PF08742
Domain	Unchr_dom_Cys-rich	VWF MUC5B MUC5AC OTOG	1.86e-07	13	77	4	IPR014853
Domain	C8	VWF MUC5B MUC5AC OTOG	1.86e-07	13	77	4	SM00832
Domain	TIL_dom	VWF MUC5B MUC5AC OTOG	2.59e-07	14	77	4	IPR002919
Domain	VWD	VWF MUC5B MUC5AC OTOG	4.68e-07	16	77	4	SM00216
Domain	VWF_type-D	VWF MUC5B MUC5AC OTOG	4.68e-07	16	77	4	IPR001846
Domain	VWFD	VWF MUC5B MUC5AC OTOG	4.68e-07	16	77	4	PS51233
Domain	VWD	VWF MUC5B MUC5AC OTOG	4.68e-07	16	77	4	PF00094
Domain	VWC_out	VWF MUC5B MUC5AC OTOG	9.87e-07	19	77	4	SM00215
Domain	CT	VWF MUC5B MUC5AC OTOG	1.85e-06	22	77	4	SM00041
Domain	Cys_knot_C	VWF MUC5B MUC5AC OTOG	3.16e-06	25	77	4	IPR006207
Domain	CTCK_2	VWF MUC5B MUC5AC OTOG	3.16e-06	25	77	4	PS01225
Domain	VWF_dom	VWF MUC5B MUC5AC OTOG	2.65e-05	42	77	4	IPR001007
Domain	CTCK_1	VWF MUC5B MUC5AC	5.26e-05	18	77	3	PS01185
Domain	Hexokinase_C	HK1 HKDC1	1.66e-04	5	77	2	IPR022673
Domain	Hexokinase_N	HK1 HKDC1	1.66e-04	5	77	2	IPR022672
Domain	Hexokinase_1	HK1 HKDC1	1.66e-04	5	77	2	PF00349
Domain	Hexokinase_2	HK1 HKDC1	1.66e-04	5	77	2	PF03727
Domain	HEXOKINASE_2	HK1 HKDC1	1.66e-04	5	77	2	PS51748
Domain	Hexokinase_BS	HK1 HKDC1	1.66e-04	5	77	2	IPR019807
Domain	HEXOKINASE_1	HK1 HKDC1	1.66e-04	5	77	2	PS00378
Domain	VWC	VWF MUC5B MUC5AC	2.05e-04	28	77	3	PF00093
Domain	Hexokinase	HK1 HKDC1	2.49e-04	6	77	2	IPR001312
Domain	WxxW_domain	MUC5B MUC5AC	2.49e-04	6	77	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	2.49e-04	6	77	2	PF13330
Domain	VWFC_1	VWF MUC5B MUC5AC	4.36e-04	36	77	3	PS01208
Domain	Sec1	SCFD2 STXBP3	4.62e-04	8	77	2	PF00995
Domain	Sec1-like	SCFD2 STXBP3	4.62e-04	8	77	2	IPR001619
Domain	-	SCFD2 STXBP3	4.62e-04	8	77	2	3.40.50.1910
Domain	Sec-1-like_dom2	SCFD2 STXBP3	4.62e-04	8	77	2	IPR027482
Domain	VWC	VWF MUC5B MUC5AC	5.12e-04	38	77	3	SM00214
Domain	VWFC_2	VWF MUC5B MUC5AC	5.12e-04	38	77	3	PS50184
Domain	Glyco_hormone_CN	MUC5B MUC5AC	1.70e-03	15	77	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	1.70e-03	15	77	2	PF00007
Domain	EGF-like_dom	CD93 LAMA3 C1R FBN3 OTOG	3.66e-03	249	77	5	IPR000742
Domain	cEGF	CD93 FBN3	5.11e-03	26	77	2	IPR026823
Domain	cEGF	CD93 FBN3	5.11e-03	26	77	2	PF12662
Domain	EGF_CA	CD93 C1R FBN3	5.39e-03	86	77	3	PF07645
Domain	EGF_Ca-bd_CS	CD93 C1R FBN3	7.53e-03	97	77	3	IPR018097
Domain	EGF_CA	CD93 C1R FBN3	7.96e-03	99	77	3	PS01187
Domain	ASX_HYDROXYL	CD93 C1R FBN3	8.18e-03	100	77	3	PS00010
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	4.84e-06	2	77	2	7513696
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	4.84e-06	2	77	2	34058148
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	4.84e-06	2	77	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	4.84e-06	2	77	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	4.84e-06	2	77	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	4.84e-06	2	77	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	4.84e-06	2	77	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	4.84e-06	2	77	2	22391959
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	4.84e-06	2	77	2	14718370
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	4.84e-06	2	77	2	35776514
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	4.84e-06	2	77	2	24327612
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	4.84e-06	2	77	2	21653907
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	4.84e-06	2	77	2	36427316
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	4.84e-06	2	77	2	28607090
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	4.84e-06	2	77	2	23272068
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	4.84e-06	2	77	2	31030254
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	4.84e-06	2	77	2	27729120
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	4.84e-06	2	77	2	23527003
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	4.84e-06	2	77	2	16540890
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	4.84e-06	2	77	2	36111525
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	4.84e-06	2	77	2	27845589
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	4.84e-06	2	77	2	27435107
Pubmed	Disruption of protein complexes containing protein phosphatase 2B and Munc18c reduces the secretion of von Willebrand factor from endothelial cells.	VWF STXBP3	4.84e-06	2	77	2	28294518
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	4.84e-06	2	77	2	26871672
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	4.84e-06	2	77	2	32348677
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	4.84e-06	2	77	2	11587997
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	4.84e-06	2	77	2	24332705
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	4.84e-06	2	77	2	34656442
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	1.45e-05	3	77	2	27776277
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.45e-05	3	77	2	29286856
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.45e-05	3	77	2	36675209
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	1.45e-05	3	77	2	29802623
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	1.45e-05	3	77	2	34158522
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	1.45e-05	3	77	2	29604272
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	1.45e-05	3	77	2	19596978
Pubmed	K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.	KRT27 KRT25	1.45e-05	3	77	2	16874310
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	1.45e-05	3	77	2	19556605
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	1.45e-05	3	77	2	21455588
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	1.45e-05	3	77	2	20422702
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	1.45e-05	3	77	2	19718741
Pubmed	Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.	KRT27 KRT25	2.89e-05	4	77	2	17920809
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	2.89e-05	4	77	2	31582416
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	2.89e-05	4	77	2	25638393
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC	2.89e-05	4	77	2	17471237
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	2.89e-05	4	77	2	21097527
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	2.89e-05	4	77	2	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC5AC	2.89e-05	4	77	2	14984930
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	2.89e-05	4	77	2	23249391
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC5AC	2.89e-05	4	77	2	29869461
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	2.89e-05	4	77	2	18258655
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC	2.89e-05	4	77	2	23807779
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC5AC	2.89e-05	4	77	2	12676567
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC5AC	4.82e-05	5	77	2	11062147
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC5AC	4.82e-05	5	77	2	16188033
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC5AC	7.22e-05	6	77	2	19110483
Pubmed	Case-control genome-wide association study of attention-deficit/hyperactivity disorder.	HK1 HKDC1	1.34e-04	8	77	2	20732627
Pubmed	Location of the 9257 and ataxia mutations on mouse chromosome 18.	ZNF521 LAMA3	1.72e-04	9	77	2	8662222
Pubmed	Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice.	HK1 HKDC1	2.15e-04	10	77	2	37545422
Pubmed	Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.	MUC5B MUC5AC	2.63e-04	11	77	2	24429156
Pubmed	Gestational loss and growth restriction by angiogenic defects in placental growth factor transgenic mice.	VWF PGF	2.63e-04	11	77	2	25147341
Pubmed	The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.	KRT27 KRT25	3.15e-04	12	77	2	15617563
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	HK1 NEURL1 RPP30 HKDC1 SORCS3 MINPP1	3.23e-04	415	77	6	16385451
Pubmed	Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.	MUC5B MUC5AC	4.33e-04	14	77	2	22797898
Pubmed	Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.	HK1 HKDC1	5.69e-04	16	77	2	23903356
Pubmed	Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.	PIGA PIGG	6.44e-04	17	77	2	11102867
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5B MUC5AC	7.23e-04	18	77	2	18834073
Pubmed	The DNA sequence and comparative analysis of human chromosome 10.	HK1 NEURL1 RPP30 SORCS3 MINPP1	1.03e-03	345	77	5	15164054
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MROH9 HSPBAP1 SMC4 SLC26A11 PGF OR52N1 FBN3	1.23e-03	736	77	7	29676528
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	SART3 WDCP RPP30 PRR14L GPRASP2	1.30e-03	364	77	5	24778252
Pubmed	Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis†.	CCR1 HSD3B2	1.89e-03	29	77	2	34007995
Pubmed	Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice.	HSD3B2 PGF	1.89e-03	29	77	2	18583422
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	1.65e-03	21	52	2	648
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGA PIGG	1.65e-03	21	52	2	680
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000	CHL1 CD93 VWF WDCP NEURL1 ZNF521 CPXM1 CCR1 HSD3B2 COL22A1 CMTR2 PGF	2.27e-05	837	72	12	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWF KRT27 LAMA3 RGS3 SEC14L1 LIMS2	4.40e-07	166	77	6	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CD93 VWF ZNF521 SEC14L1 CCSER1 LIMS2	8.29e-07	185	77	6	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MROH9 AJAP1 CIP2A MUC5B HSD3B2	1.29e-05	174	77	5	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	1.48e-05	179	77	5	8f9e538c822940785130297712b75131812a4603
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CD93 VWF RGS3 SEC14L1 LIMS2	1.48e-05	179	77	5	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	1.52e-05	180	77	5	16728b9a1c52097e3a460534be71a476ecc54f0f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 LAMA3 PIGG SLC26A11 RGS3	1.56e-05	181	77	5	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF PGF SEC14L1 LIMS2	1.69e-05	184	77	5	a12a6a481e78adc62da1904431f62b119f70b15f
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CD93 VWF ZNF521 SORCS3 LIMS2	1.73e-05	185	77	5	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 VWF ZNF521 RGS3 SEC14L1	1.73e-05	185	77	5	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	1.82e-05	187	77	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	CHL1 CD93 VWF SEC14L1 LIMS2	1.87e-05	188	77	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CD93 VWF ZNF521 SEC14L1 LIMS2	1.92e-05	189	77	5	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	ARFGEF3 PTPN3 MUC5B MUC5AC CCSER1	1.92e-05	189	77	5	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 VWF AJAP1 LAMA3 LIMS2	1.97e-05	190	77	5	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CHL1 CD93 VWF SEC14L1 LIMS2	1.97e-05	190	77	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	CHL1 ARFGEF3 MUC5B MUC5AC CCSER1	1.97e-05	190	77	5	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CHL1 PTPN3 HKDC1 SORCS3 CCSER1	2.02e-05	191	77	5	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF LAMA3 SEC14L1 LIMS2	2.07e-05	192	77	5	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.17e-05	194	77	5	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.17e-05	194	77	5	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.17e-05	194	77	5	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CD93 VWF ZNF521 SEC14L1 LIMS2	2.23e-05	195	77	5	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF LAMA3 SEC14L1 LIMS2	2.23e-05	195	77	5	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF LAMA3 SEC14L1 LIMS2	2.23e-05	195	77	5	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 VWF CDC42BPB RGS3 LIMS2	2.23e-05	195	77	5	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	473980c827443464d08a0be28c53e3536369b12a
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.28e-05	196	77	5	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.34e-05	197	77	5	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.34e-05	197	77	5	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PGF RGS3 SEC14L1 LIMS2	2.34e-05	197	77	5	a312d9cf4ced949307eb9620be4eed926300b892
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.34e-05	197	77	5	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.34e-05	197	77	5	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD93 VWF PGF RGS3 SEC14L1	2.34e-05	197	77	5	15d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.40e-05	198	77	5	07701c73137947ed4a27e225975329235bbb8734
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.40e-05	198	77	5	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.40e-05	198	77	5	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 CD93 VWF SEC14L1 LIMS2	2.40e-05	198	77	5	002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell	Parenchymal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD93 VWF ZNF521 SEC14L1 LIMS2	2.46e-05	199	77	5	a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 SEC14L1 LIMS2	2.46e-05	199	77	5	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD93 VWF PGF RGS3 LIMS2	2.46e-05	199	77	5	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD93 VWF PGF RGS3 LIMS2	2.46e-05	199	77	5	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CD93 VWF ZNF521 SEC14L1 LIMS2	2.52e-05	200	77	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 VWF ZNF521 SEC14L1 LIMS2	2.52e-05	200	77	5	074b5766c61fa8e61d0b1b76688ea0d1ec401e5b
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CHL1 MROH9 SORCS3 CCSER1 LIMS2	2.52e-05	200	77	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	(05)_Ciliated-(2)_48hpi\|(05)_Ciliated / shred by cell type and Timepoint	ARFGEF3 CCR1 GREB1 OTOG	6.37e-05	124	77	4	fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Nrp2_(Anterior_thalamus)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MROH9 KRT27 HSD3B2	7.89e-05	48	77	3	0553da597a3c02ab3ccdcd9aafda89dc6f8bfb20
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 HKDC1 GREB1 ALPK2	8.60e-05	134	77	4	72d7eec3aeb43319f3ef81bb5518fae8d8880136
ToppCell	MS-CD4-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	NOTUM HKDC1 OR10J1 OTOG	1.05e-04	141	77	4	df257dd4dcc45c1ace57340798e150a6e932531d
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWF ZNF521 RGS3 LIMS2	1.33e-04	150	77	4	4f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN3 NEURL1 SIRT5 FBN3	1.47e-04	154	77	4	ce4b1e878cd88065fbfd2df18caf19703fec37d8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ZNF521 SEC14L1 LIMS2	1.55e-04	156	77	4	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	Control-Endothelial_cells-Inflamed_endothelial_cells\|Control / group, cell type (main and fine annotations)	CD93 VWF SEC14L1 LIMS2	1.70e-04	160	77	4	958256e3d3836160763b82bb48f794087918d935
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	CD93 VWF SEC14L1 LIMS2	1.70e-04	160	77	4	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 VWF ZNF521 LIMS2	1.83e-04	163	77	4	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD93 CIP2A SMC4 MINPP1	1.83e-04	163	77	4	7864e966c228282b4b63c43164dba3faba21026d
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 WDCP MUC5B MUC5AC	1.96e-04	166	77	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 WDCP MUC5B MUC5AC	1.96e-04	166	77	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 WDCP MUC5B MUC5AC	1.96e-04	166	77	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	Control\|World / group, cell type (main and fine annotations)	ARFGEF3 LAMA3 MUC5AC CCSER1	2.05e-04	168	77	4	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PITPNM1 CIP2A CCR1 SIRT5	2.05e-04	168	77	4	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD93 VWF ZNF521 LIMS2	2.15e-04	170	77	4	1a568efcff9c39b3f709b55a05d24710450a2657
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD93 VWF ZNF521 LIMS2	2.15e-04	170	77	4	66d41d794790e621d72ac37af995510537103c9c
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHL1 SCFD2 NOTUM CPXM1	2.20e-04	171	77	4	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FSIP2 LAMA3 MUC5B MUC5AC	2.25e-04	172	77	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CHL1 CD93 VWF LIMS2	2.25e-04	172	77	4	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD93 VWF RGS3 LIMS2	2.30e-04	173	77	4	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	droplet-Heart-4Chambers-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 VWF RGS3 LIMS2	2.30e-04	173	77	4	9a04271c51fae34f547db3206f9ff5857686e45c
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	CHL1 ARFGEF3 MUC5B MUC5AC	2.35e-04	174	77	4	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CIP2A SMC4 POLQ RGS3	2.40e-04	175	77	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 PIGA NEURL1 FBN3	2.45e-04	176	77	4	cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCell	normal_Lung-Endothelial_cells-EPCs\|normal_Lung / Location, Cell class and cell subclass	CD93 VWF SEC14L1 LIMS2	2.45e-04	176	77	4	71d1bd425772d89d8c550b909e0ec0e36ff22a7e
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CHL1 CD93 VWF LIMS2	2.50e-04	177	77	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD93 VWF ZNF521 SEC14L1	2.50e-04	177	77	4	1921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 ARFGEF3 MUC5B MUC5AC	2.50e-04	177	77	4	779ba86f53650772755b52460be03f18bb204e55
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 AJAP1 NOTUM RORC	2.50e-04	177	77	4	291231b1520c135e92739e201495fe1935efa927
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 ARFGEF3 MUC5B MUC5AC	2.50e-04	177	77	4	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NOTUM CCR1 RORC FERMT3	2.56e-04	178	77	4	f52f837e948deb6a2d031325f49891bca8d375da
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CHL1 CD93 VWF LIMS2	2.56e-04	178	77	4	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CD93 ZNF521 COL22A1 ALPK2	2.61e-04	179	77	4	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	CHL1 ARFGEF3 MUC5B MUC5AC	2.61e-04	179	77	4	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARFGEF3 PTPN3 LAMA3 RORC	2.61e-04	179	77	4	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	Endothelial\|World / shred by cell class for turbinate	CD93 VWF ZNF521 LIMS2	2.61e-04	179	77	4	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CIP2A SMC4 LAMA3 POLQ	2.61e-04	179	77	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD93 VWF NOTUM SIRT5	2.67e-04	180	77	4	2405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	ERV3-1 NEURL1 HKDC1 ANKMY1	2.67e-04	180	77	4	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	CD93 VWF RGS3 LIMS2	2.67e-04	180	77	4	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	CHL1 ARFGEF3 MUC5B MUC5AC	2.67e-04	180	77	4	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CD93 VWF RGS3 LIMS2	2.67e-04	180	77	4	394cd465b88429b70eebb2957480dffcbc51cfe7
Disease	complement C1q subcomponent measurement	CD93 C1R	9.00e-05	6	73	2	EFO_0008089
Disease	Hereditary clear cell renal cell carcinoma	HSPBAP1 RNF139	1.26e-04	7	73	2	C1333985
Disease	pulmonary fibrosis	MUC5B MUC5AC	3.27e-04	11	73	2	EFO_0009448
Disease	sickle cell anemia (is_marker_for)	HK1 PGF	5.39e-04	14	73	2	DOID:10923 (is_marker_for)
Disease	carotid artery disease (is_marker_for)	VWF PGF	1.00e-03	19	73	2	DOID:3407 (is_marker_for)
Disease	haptoglobin measurement	ZNF19 CMTR2	1.23e-03	21	73	2	EFO_0004640
Disease	glucose metabolism disease (implicated_via_orthology)	HK1 HKDC1	2.19e-03	28	73	2	DOID:4194 (implicated_via_orthology)
Disease	posterior urethral valve	UBR2 ALPK2	2.35e-03	29	73	2	MONDO_0019640
Disease	Strabismus	RGS3 CCSER1	2.35e-03	29	73	2	HP_0000486

Protein segments in the cluster

Peptide	Gene	Start	Entry
CQVCHYRSSVFADVE	ZNF280A	396	P59817
ENIASSLHVASCYVC	ERV3-1	281	Q14264
ACQDVSVVIHTACII	HSD3B2	71	P26439
LSCQFAEIHEDSTIC	ALPK2	1806	Q86TB3
IFTAYNETLQCSHEC	AJAP1	346	Q9UKB5
TEAVVCVGTACYTAH	CD93	26	Q9NPY3
QQYSCSCHVFSEELI	CMTR2	541	Q8IYT2
LHTNCFEVTVELSCD	CPXM1	581	Q96SM3
CREDSYHSVVSCAAV	CCSER1	536	Q9C0I3
CVDTHVRSTCYGAIE	FBN3	611	Q75N90
THSCQAECSSELYTE	C1R	186	P00736
VNSHVDNCTVYLCEA	MUC5B	5606	Q9HC84
ECACTSTYVNELVVF	OR8B8	186	Q15620
CEEVCHVSVLSVLST	RGS3	76	P49796
HIQCQSEDCTIAYVS	PTPN3	771	P26045
EHQSVYCVLTVAEVC	L3MBTL3	276	Q96JM7
VCYNCSHVIEGDVVS	LIMS2	256	Q7Z4I7
SCNYSVLCRSAVIDH	LAMA3	991	Q16787
VTLEDQGIYCCSAHT	CHL1	581	O00533
SCNDSVHVIECAYSL	GREB1	511	Q4ZG55
VECSVVTEFTDHICV	KIAA1109	4841	Q2LD37
DDSSIYQCCEHLTES	FSIP2	3491	Q5CZC0
STCVCHICAVTIFYV	OR51T1	241	Q8NGJ9
HSLECSLTETESNYC	KRT27	326	Q7Z3Y8
HSLECSLTETESNYC	KRT25	321	Q7Z3Z0
TDLLSCVCHTLAEYS	MUC5AC	301	P98088
LDVLVCLYTECSHSA	CDC42BPB	31	Q9Y5S2
TEVSFVDCEQLCSHF	MROH9	531	Q5TGP6
DDCVSVQHVCTIVSF	HK1	366	P19367
NKQYRHTDCVDTITC	NOTUM	271	Q6P988
TEVEETSHAVNCCYL	HSPBAP1	311	Q96EW2
CSHTCVAVLDNFVYV	KLHL26	351	Q53HC5
SYSIVCYHVLCTSEV	QRSL1	321	Q9H0R6
LAVQVTEVIAYTHCC	CCR1	281	P32246
TEVIAYTHCCVNPVI	CCR1	286	P32246
VCIETYISSCHQRSI	ARFGEF3	141	Q5TH69
VVSLCYETICDNHSV	POLQ	326	O75417
VAVTLYQHVCVHLCT	C1orf112	411	Q9NSG2
SALCVACDLTYEHQR	ANKMY1	731	Q9P2S6
IVIYCDSRHAELETC	COL22A1	421	Q8NFW1
LADQYDAICCHTSTS	TMEM259	386	Q4ZIN3
TVAHCISVSQDYIFC	MAPKBP1	281	O60336
QCTSDYPEHVCEVLL	SART3	536	Q15020
TFSNRVIINEHCCYT	SEC14L1	101	Q92503
ELQRTHVESCCEETY	PRR14L	66	Q5THK1
CASHLTVVIVHYSCA	OR10J1	251	P30954
FYQINTTSVLCDIHC	OTOG	2726	Q6ZRI0
CASHLIVVTVHYSCA	OR10K1	241	Q8NGX5
STCTAHFCAIVLTYV	OR52N1	241	Q8NH53
VCAICYHEFTTSARI	RNF139	546	Q8WU17
ACTHLDVDLVCITVT	RPP30	116	P78346
ISVHVFYRCQCTTVE	PPARD	241	Q03181
LHYDTVCQETSPTCD	TDRD15	276	B5MCY1
ADCIAVQHVCTIVSF	HKDC1	366	Q2TB90
AHYLTCRIQECAETT	SORCS3	366	Q9UPU3
CTSCHNVTERYQEVT	TAF1B	31	Q53T94
ETFICQVCEETLAHS	GPRASP2	676	Q96D09
HIICNSYGCTDDIVT	INPPL1	701	O15357
DIICRSHFQYCVVVT	SCFD2	91	Q8WU76
CAYEVSQAHKSCEVI	STXBP3	546	O00186
VVCRSSHTDSVFLQC	CIP2A	106	Q8TCG1
HLYISNCISTCEQIK	CNOT11	426	Q9UKZ1
CDTNHIICVSYTSKE	PIGA	176	P37287
HTYAECCLTVVARGT	PITPNM1	1006	O00562
LRIHTQESSYVCDEC	ZNF19	376	P17023
EHLVQSVCKSYRETC	RORC	271	P51449
DSCHQEQVCEVIASY	VWF	2166	P04275
VGSCKSEVEVDIHYC	VWF	2736	P04275
HYKDILQSCQTSEEC	MINPP1	461	Q9UNW1
CTICYEHAVDTVIYT	NEURL1	521	O76050
LECTHVCSIDYTVVL	SLC26A11	516	Q86WA9
SYVELTFSQHVRCEC	PGF	116	P49763
DSHQSEQTLCVVCFS	RNF44	371	Q7L0R7
LQCVYCHELFVEETS	ZNF521	281	Q96K83
VAISSCCHALDYIVV	SMC4	631	Q9NTJ3
FSCVSASCRIVHEYI	FERMT3	621	Q86UX7
LHLYCSSQEVLCQIV	NIPAL4	16	Q0D2K0
SCLVFDVDSHVCSIT	WDCP	196	Q9H6R7
VHVIVCTSAESSCYF	PIGG	486	Q5H8A4
HCDLCLVVGTSSVVY	SIRT5	241	Q9NXA8
ICGHSVETIRYCVSQ	UBR2	591	Q8IWV8