Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA helicase activity	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	3.31e-07	78	170	8	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	4.03e-07	80	170	8	GO:0008186
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DNAH17 DNAH5 DNAH9	1.41e-05	18	170	4	GO:0008569
GeneOntologyMolecularFunction	helicase activity	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	6.38e-05	158	170	8	GO:0004386
GeneOntologyMolecularFunction	intracellular sodium-activated potassium channel activity	KCNT2 KCNT1	7.21e-05	2	170	2	GO:0005228
GeneOntologyMolecularFunction	ATP-dependent activity	DHX36 MYH3 DDX60 DHX38 DDX51 SMC2 IFIH1 ATP6V0D1 DNAH12 DNAH17 RAD54B ACSF3 DDX60L DNAH5 DHX34 DNAH9	7.40e-05	614	170	16	GO:0140657
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DNAH17 DNAH5 DNAH9	8.85e-05	28	170	4	GO:0051959
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DHX36 DDX60 DHX38 POLR1C TRMT1 DDX51 IFIH1 RAD54B N4BP1 DDX60L DHX34 SMG6	2.47e-04	417	170	12	GO:0140098
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH12 DNAH17 DNAH5 DNAH9	2.69e-04	37	170	4	GO:0045505
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 MYH3 DDX60 DHX38 DDX51 SMC2 IFIH1 DNAH12 DDX60L DNAH5 DHX34 DNAH9	4.10e-04	441	170	12	GO:0016887
GeneOntologyMolecularFunction	double-stranded RNA binding	DHX36 DDX60 OAS3 IFIH1 DDX60L	5.39e-04	78	170	5	GO:0003725
GeneOntologyBiologicalProcess	protein catabolic process	UBL7 DCAF1 NRG1 VPS11 CACUL1 ARRDC1 FBXL12 CUL9 RDX PSMD3 SPG11 IDS YJEFN3 SKP2 TRIP12 OXA1L COMMD1 PSME4 USP38 P2RX7 NFE2L1 TMEM132A FAM83D N4BP1 HERC2 OGA CTSK	4.54e-07	1115	170	27	GO:0030163
GeneOntologyCellularComponent	axonemal dynein complex	DNAH12 DNAH17 DNAH5 DNAH9	4.78e-05	25	171	4	GO:0005858
GeneOntologyCellularComponent	outer dynein arm	DNAH17 DNAH5 DNAH9	1.12e-04	12	171	3	GO:0036157
GeneOntologyCellularComponent	stereocilium	CDH23 RDX ADGRV1 LOXHD1 PCDH15	2.54e-04	69	171	5	GO:0032420
GeneOntologyCellularComponent	axon	MAG DHX36 NRG1 PCDHGB1 ESR1 LMTK2 CRTAC1 SPG11 SYBU LMTK3 BCR MADD ITPR2 TH ATP6V0D1 P2RX7 SYT11 TRPM1	3.82e-04	891	171	18	GO:0030424
GeneOntologyCellularComponent	stereocilium bundle	CDH23 RDX ADGRV1 LOXHD1 PCDH15	4.78e-04	79	171	5	GO:0032421
GeneOntologyCellularComponent	subapical complex	MPDZ PATJ	6.55e-04	5	171	2	GO:0035003
GeneOntologyCellularComponent	cytoplasmic region	RSPH4A SYBU CFAP210 MADD DNAH12 DNAH17 RIMS4 DNAAF1 DNAH5 DNAH9	7.88e-04	360	171	10	GO:0099568
GeneOntologyCellularComponent	peptidase complex	SUPT20HL1 SUPT20H PSMD3 PSMD5 SUPT20HL2 PSME4	7.99e-04	133	171	6	GO:1905368
GeneOntologyCellularComponent	dynein complex	DNAH12 DNAH17 DNAH5 DNAH9	9.94e-04	54	171	4	GO:0030286
GeneOntologyCellularComponent	SAGA complex	SUPT20HL1 SUPT20H SUPT20HL2	1.08e-03	25	171	3	GO:0000124
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	RSPH4A SYBU CFAP210 MADD DNAH12 DNAH17 DNAAF1 DNAH5 DNAH9	1.23e-03	317	171	9	GO:0032838
Domain	Helicase_C	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.08e-06	107	166	8	PF00271
Domain	HELICc	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.08e-06	107	166	8	SM00490
Domain	Helicase_C	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.45e-06	108	166	8	IPR001650
Domain	HELICASE_CTER	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.83e-06	109	166	8	PS51194
Domain	HELICASE_ATP_BIND_1	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.83e-06	109	166	8	PS51192
Domain	DEXDc	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	5.83e-06	109	166	8	SM00487
Domain	Helicase_ATP-bd	DHX36 DDX60 DHX38 DDX51 IFIH1 RAD54B DDX60L DHX34	6.24e-06	110	166	8	IPR014001
Domain	DEAD/DEAH_box_helicase_dom	DHX36 DDX60 DHX38 DDX51 DDX60L DHX34	4.69e-05	73	166	6	IPR011545
Domain	DEAD	DHX36 DDX60 DHX38 DDX51 DDX60L DHX34	4.69e-05	73	166	6	PF00270
Domain	L27_2	MPDZ PATJ	7.85e-05	2	166	2	PF09045
Domain	Spt20	SUPT20H SUPT20HL2	7.85e-05	2	166	2	IPR021950
Domain	L27_2	MPDZ PATJ	7.85e-05	2	166	2	IPR015132
Domain	Spt20	SUPT20H SUPT20HL2	7.85e-05	2	166	2	PF12090
Domain	-	DCAF1 CUL9 PSMD5 IPO4 TRIP12 VAC14 PSME4 ANKAR HEATR5B	1.70e-04	222	166	9	1.25.10.10
Domain	ARM-type_fold	DCAF1 VPS11 CUL9 PSMD5 IPO4 TRIP12 ITPR2 VAC14 PSME4 ANKAR HEATR5B	2.32e-04	339	166	11	IPR016024
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	IPR013602
Domain	DHC_N2	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	IPR011704
Domain	AAA_8	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	PF12780
Domain	AAA_5	DNAH12 DNAH5 DNAH9	2.34e-04	14	166	3	PF07728
Domain	Cul7	CUL9 HERC2	2.34e-04	3	166	2	PF11515
Domain	CPH_domain	CUL9 HERC2	2.34e-04	3	166	2	IPR021097
Domain	DHC_fam	DNAH12 DNAH5 DNAH9	2.90e-04	15	166	3	IPR026983
Domain	Dynein_heavy	DNAH12 DNAH5 DNAH9	2.90e-04	15	166	3	PF03028
Domain	Dynein_heavy_dom	DNAH12 DNAH5 DNAH9	2.90e-04	15	166	3	IPR004273
Domain	DUF1605	DHX36 DHX38 DHX34	4.28e-04	17	166	3	IPR011709
Domain	OB_NTP_bind	DHX36 DHX38 DHX34	4.28e-04	17	166	3	PF07717
Domain	BK_channel_a	KCNT2 KCNT1	4.66e-04	4	166	2	PF03493
Domain	K_chnl_Ca-activ_BK_asu	KCNT2 KCNT1	4.66e-04	4	166	2	IPR003929
Domain	HA2	DHX36 DHX38 DHX34	5.10e-04	18	166	3	SM00847
Domain	HA2	DHX36 DHX38 DHX34	5.10e-04	18	166	3	PF04408
Domain	Helicase-assoc_dom	DHX36 DHX38 DHX34	5.10e-04	18	166	3	IPR007502
Domain	ARM-like	DCAF1 CUL9 PSMD5 IPO4 TRIP12 VAC14 PSME4 ANKAR HEATR5B	7.10e-04	270	166	9	IPR011989
Domain	RIH_assoc-dom	RYR1 ITPR2	1.15e-03	6	166	2	IPR013662
Domain	Ins145_P3_rec	RYR1 ITPR2	1.15e-03	6	166	2	PF08709
Domain	RIH_assoc	RYR1 ITPR2	1.15e-03	6	166	2	PF08454
Domain	RIH_dom	RYR1 ITPR2	1.15e-03	6	166	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 ITPR2	1.15e-03	6	166	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 ITPR2	1.15e-03	6	166	2	IPR015925
Domain	-	RYR1 ITPR2	1.15e-03	6	166	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 ITPR2	1.15e-03	6	166	2	PF01365
Domain	APC_su10/DOC_dom	CUL9 HERC2	1.60e-03	7	166	2	IPR004939
Domain	DOC	CUL9 HERC2	1.60e-03	7	166	2	PS51284
Domain	ANAPC10	CUL9 HERC2	1.60e-03	7	166	2	PF03256
Domain	APC10	CUL9 HERC2	1.60e-03	7	166	2	SM01337
Domain	DHC_N1	DNAH5 DNAH9	2.12e-03	8	166	2	PF08385
Domain	MacrogloblnA2_thiol-ester-bond	CD109 A2ML1	2.12e-03	8	166	2	IPR019565
Domain	Calx_beta	ADGRV1 ITGB4	2.12e-03	8	166	2	SM00237
Domain	Thiol-ester_cl	CD109 A2ML1	2.12e-03	8	166	2	PF10569
Domain	MacrogloblnA2_CS	CD109 A2ML1	2.12e-03	8	166	2	IPR019742
Domain	A2M_N_2	CD109 A2ML1	2.12e-03	8	166	2	SM01359
Domain	-	CD109 A2ML1	2.12e-03	8	166	2	2.60.40.690
Domain	Dynein_heavy_dom-1	DNAH5 DNAH9	2.12e-03	8	166	2	IPR013594
Domain	A2M_recep	CD109 A2ML1	2.12e-03	8	166	2	SM01361
Domain	A2M	CD109 A2ML1	2.12e-03	8	166	2	SM01360
Domain	Calx_beta	ADGRV1 ITGB4	2.71e-03	9	166	2	IPR003644
Domain	Calx-beta	ADGRV1 ITGB4	2.71e-03	9	166	2	PF03160
Domain	Cadherin_CS	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	2.90e-03	109	166	5	IPR020894
Domain	MIR	RYR1 ITPR2	3.37e-03	10	166	2	PF02815
Domain	A2M	CD109 A2ML1	3.37e-03	10	166	2	PF00207
Domain	MIR_motif	RYR1 ITPR2	3.37e-03	10	166	2	IPR016093
Domain	A2M_N_2	CD109 A2ML1	3.37e-03	10	166	2	IPR011625
Domain	A2M_comp	CD109 A2ML1	3.37e-03	10	166	2	IPR011626
Domain	Cullin	CACUL1 CUL9	3.37e-03	10	166	2	PF00888
Domain	A2M_recep	CD109 A2ML1	3.37e-03	10	166	2	PF07677
Domain	A2M_comp	CD109 A2ML1	3.37e-03	10	166	2	PF07678
Domain	A2M_N	CD109 A2ML1	3.37e-03	10	166	2	PF01835
Domain	MIR	RYR1 ITPR2	3.37e-03	10	166	2	PS50919
Domain	MIR	RYR1 ITPR2	3.37e-03	10	166	2	SM00472
Domain	A2M_N	CD109 A2ML1	3.37e-03	10	166	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	CD109 A2ML1	3.37e-03	10	166	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CD109 A2ML1	3.37e-03	10	166	2	PS00477
Domain	CULLIN_2	CACUL1 CUL9	3.37e-03	10	166	2	PS50069
Domain	A2M_N_2	CD109 A2ML1	3.37e-03	10	166	2	PF07703
Domain	Cullin_N	CACUL1 CUL9	3.37e-03	10	166	2	IPR001373
Domain	Macroglobln_a2	CD109 A2ML1	3.37e-03	10	166	2	IPR001599
Domain	CULLIN_1	CACUL1 CUL9	3.37e-03	10	166	2	PS01256
Domain	CADHERIN_1	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.39e-03	113	166	5	PS00232
Domain	Cadherin	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.39e-03	113	166	5	PF00028
Domain	HEAT_REPEAT	IPO4 VAC14 PSME4 HEATR5B	3.50e-03	70	166	4	PS50077
Domain	CADHERIN_2	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.52e-03	114	166	5	PS50268
Domain	-	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.52e-03	114	166	5	2.60.40.60
Domain	CA	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.65e-03	115	166	5	SM00112
Domain	DNA/RNA_helicase_DEAH_CS	DHX36 DHX38 DHX34	3.66e-03	35	166	3	IPR002464
Domain	Cadherin-like	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	3.79e-03	116	166	5	IPR015919
Domain	Cadherin	PCDHGB1 PCDHGA5 CDH23 FAT1 PCDH15	4.08e-03	118	166	5	IPR002126
Domain	DEAH_ATP_HELICASE	DHX36 DHX38 DHX34	4.63e-03	38	166	3	PS00690
Domain	-	CD109 A2ML1	4.89e-03	12	166	2	1.50.10.20
Domain	EGF	NRG1 F9 FAT1 THBS4 NRXN3	5.38e-03	126	166	5	PF00008
Domain	L27	MPDZ PATJ	5.74e-03	13	166	2	SM00569
Domain	L27	MPDZ PATJ	5.74e-03	13	166	2	PS51022
Domain	L27_dom	MPDZ PATJ	5.74e-03	13	166	2	IPR004172
Domain	Dynein_HC_stalk	DNAH5 DNAH9	6.66e-03	14	166	2	IPR024743
Domain	MT	DNAH5 DNAH9	6.66e-03	14	166	2	PF12777
Domain	EGF_1	NRG1 CRTAC1 ITGB4 F9 FAT1 THBS4 NRXN3	7.89e-03	255	166	7	PS00022
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DCTN6 DNAH17 DNAH5 DNAH9	1.78e-06	27	109	5	M47755
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DCTN6 DNAH17 DNAH5 DNAH9	1.92e-05	43	109	5	M47669
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DCTN6 DNAH17 DNAH5 DNAH9	2.41e-05	45	109	5	M47670
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 ZXDC RARG TMC6 HECTD4 FBXL12 LMTK2 TRMT1 CUL9 ANKLE1 BCR ITGB4 RYR1 TBC1D9 MADD MAP3K5 ITPR2 NCOR1 VAC14 FAT1 PSME4 PER2 ZMIZ2 TMEM132A HERC2 ZC3H7B ESPL1 PPP2R3C DHX34 SMG6	5.04e-14	1105	175	30	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DHX36 PDPR VPS13C HECTD4 LMTK2 SPG11 ADGRV1 BCR NRXN3 PSME4 USP38 ZC3H7B ESPL1 OGA DHX34 NBR1 KCNT1 SMG6	2.36e-10	529	175	18	14621295
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	DCAF1 VPS11 ARRDC1 LMTK2 CUL9 PSMD3 IPO4 SMC2 BCR ATP6V0D1 KLHL12 HERC2	7.25e-08	313	175	12	38270169
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20H SUPT20HL2	1.25e-07	3	175	3	24220028
Pubmed	Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats.	HLCS NCOR1 HDAC1	1.25e-07	3	175	3	24840043
Pubmed	Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.	SUPT20HL1 SUPT20H SUPT20HL2 LEPR	1.99e-07	11	175	4	24051374
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DHX36 DMXL2 ACOT9 DHX38 MPDZ RDX SMC2 INTS3 BCR MADD PSME4 RAD54B PATJ ZC3H7B DHX34 ZNF574	2.16e-07	650	175	16	38777146
Pubmed	Role for a novel Usher protein complex in hair cell synaptic maturation.	CDH23 ADGRV1 PCDH15	4.99e-07	4	175	3	22363448
Pubmed	Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.	CDH23 ADGRV1 PCDH15	4.99e-07	4	175	3	33009420
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DMXL2 SUPT20H POLR1C HECTD4 HLCS CUL9 RDX CRTAC1 PSMD5 IDS TRIP12 MADD WDR3 KANSL2 COMMD1 DCTN6 ZNF451 CKAP2 HERC2 USPL1 DOP1B ZNF292	5.86e-07	1285	175	22	35914814
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	UBL7 HECTD4 LMTK2 PSMD3 PSMD5 TRIP12 PPM1B GTF2E1 USP38 ZNF451 N4BP1 HERC2 NBR1	1.11e-06	481	175	13	28190767
Pubmed	Recruitment of distinct chromatin-modifying complexes by tamoxifen-complexed estrogen receptor at natural target gene promoters in vivo.	ESR1 NCOR1 HDAC1	1.24e-06	5	175	3	14722073
Pubmed	Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.	PSMD5 TRIP12 PSME4 SYT11 NBR1	2.23e-06	42	175	5	7584044
Pubmed	TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells.	CDH23 LOXHD1 PCDH15	2.48e-06	6	175	3	23217710
Pubmed	CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.	RSPH4A DNAH5 DNAH9	2.48e-06	6	175	3	33347437
Pubmed	Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.	CDH23 ADGRV1 PCDH15	4.32e-06	7	175	3	20058854
Pubmed	Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.	ASXL1 ESR1 NCOR1	4.32e-06	7	175	3	16606617
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH17 DNAH5 DNAH9	4.32e-06	7	175	3	31178125
Pubmed	Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.	SUPT20HL1 SUPT20H SUPT20HL2	6.88e-06	8	175	3	21802298
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	CDH23 ADGRV1 PCDH15	6.88e-06	8	175	3	19683999
Pubmed	Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.	CDH23 ADGRV1 PCDH15	1.03e-05	9	175	3	28705869
Pubmed	SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.	ESR1 NCOR1 HDAC1	1.03e-05	9	175	3	9702189
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	ZXDC ARRDC1 CD109 CUL9 SEZ6L2 RYR1 DNAH5 DOP1B	1.39e-05	214	175	8	22199357
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DCAF1 ASXL1 SUPT20H DHX38 POLR1C MPDZ RDX PSMD3 IPO4 BCR SKP2 TRIP12 WDR3 USP38 HERC2 USPL1 OGA	1.42e-05	1005	175	17	19615732
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	CDH23 ADGRV1 PCDH15	1.46e-05	10	175	3	24618850
Pubmed	Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.	ESR1 NCOR1 HDAC1	1.46e-05	10	175	3	24051437
Pubmed	A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.	CDH23 ADGRV1 LOXHD1	1.46e-05	10	175	3	17329413
Pubmed	Usher protein functions in hair cells and photoreceptors.	CDH23 ADGRV1 PCDH15	1.46e-05	10	175	3	24239741
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 DHX36 DHX38 POLR1C OAS3 PSMD3 PSMD5 DDX51 IPO4 SMC2 NDUFB4 TRIP12 WDR3 PSME4 EIF2B4 A2ML1 IQSEC1 DDX60L HERC2 DHX34	1.72e-05	1353	175	20	29467282
Pubmed	Strain background effects and genetic modifiers of hearing in mice.	CDH23 ADGRV1 PCDH15	2.01e-05	11	175	3	16579977
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DHX36 NOP16 ACOT9 DDX60 DHX38 POLR1C CD109 OAS3 PSMD3 IPO4 SMC2 TRIP12 ITGB4 ITPR2 WDR3 EIF2B4 CKAP2 PATJ HDAC1	2.09e-05	1257	175	19	36526897
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	NOP16 ARRDC1 TMC6 ANKLE1 CYP39A1 PALB2 COMMD1 PSME4 LRRC3B DCTN6 ZMIZ2 USPL1 PPP2R3C DHX34 ZNF574	2.24e-05	832	175	15	36724073
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	KNTC1 VPS13C HLCS MPDZ SPG11 BCR MADD ITPR2 ZNF451 N4BP1 CKAP2 PATJ ESPL1 NBR1	2.27e-05	733	175	14	34672954
Pubmed	Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.	KCNT2 KCNT1	2.52e-05	2	175	2	25347289
Pubmed	Neuregulin 1 Improves Glucose Tolerance in db/db Mice.	NRG1 LEPR	2.52e-05	2	175	2	26230680
Pubmed	Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population.	NRG1 ITGB4	2.52e-05	2	175	2	32418639
Pubmed	Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.	CDH23 PCDH15	2.52e-05	2	175	2	29261728
Pubmed	Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.	KCNT2 KCNT1	2.52e-05	2	175	2	17344399
Pubmed	Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.	ESR1 LMTK3	2.52e-05	2	175	2	21602804
Pubmed	Allelic hierarchy of CDH23 mutations causing non-syndromic deafness DFNB12 or Usher syndrome USH1D in compound heterozygotes.	CDH23 PCDH15	2.52e-05	2	175	2	21940737
Pubmed	Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.	CDH23 PCDH15	2.52e-05	2	175	2	15537665
Pubmed	A novel missense mutation locus of cadherin 23 and the interaction of cadherin 23 and protocadherin 15 in a patient with usher syndrome.	CDH23 PCDH15	2.52e-05	2	175	2	32835555
Pubmed	ITGB4 deficiency induces DNA damage by downregulating HDAC1 in airway epithelial cells under stress stimulation.	ITGB4 HDAC1	2.52e-05	2	175	2	36282138
Pubmed	PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression.	ESR1 HDAC1	2.52e-05	2	175	2	25801958
Pubmed	Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men.	ESR1 LEPR	2.52e-05	2	175	2	12457453
Pubmed	Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.	CDH23 PCDH15	2.52e-05	2	175	2	20739546
Pubmed	Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells.	CDH23 PCDH15	2.52e-05	2	175	2	23451239
Pubmed	The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.	CDH23 ADGRV1	2.52e-05	2	175	2	15820310
Pubmed	Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha.	ESR1 HDAC1	2.52e-05	2	175	2	14506733
Pubmed	Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction.	CDH23 PCDH15	2.52e-05	2	175	2	23135401
Pubmed	ER stress increases expression of intracellular calcium channel RyR1 to modify Ca2+ homeostasis in pancreatic beta cells.	LEPR RYR1	2.52e-05	2	175	2	37468098
Pubmed	A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.	CDH23 PCDH15	2.52e-05	2	175	2	19270079
Pubmed	The clock gene Per2 links the circadian system to the estrogen receptor.	ESR1 PER2	2.52e-05	2	175	2	17599055
Pubmed	Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.	KCNT2 KCNT1	2.52e-05	2	175	2	26845140
Pubmed	Genetic interaction of purinergic P2X7 receptor and ER-α polymorphisms in susceptibility to osteoporosis in Chinese postmenopausal women.	ESR1 P2RX7	2.52e-05	2	175	2	28884379
Pubmed	Molecular mechanisms of Slo2 K+ channel closure.	KCNT2 KCNT1	2.52e-05	2	175	2	27682982
Pubmed	PATJ and MPDZ are required for trophectoderm lineage specification in early mouse embryos.	MPDZ PATJ	2.52e-05	2	175	2	37318097
Pubmed	Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration.	CDH23 PCDH15	2.52e-05	2	175	2	19057657
Pubmed	A Significant Difference in Core PDZ Interactivity of SARS-CoV, SARS-CoV2 and MERS-CoV Protein E Peptide PDZ Motifs In Vitro.	MPDZ PATJ	2.52e-05	2	175	2	36932261
Pubmed	Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.	CDH23 PCDH15	2.52e-05	2	175	2	21532990
Pubmed	Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists.	ESR1 NCOR1	2.52e-05	2	175	2	12145334
Pubmed	Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.	KCNT2 KCNT1	2.52e-05	2	175	2	26587966
Pubmed	Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice.	KCNT2 KCNT1	2.52e-05	2	175	2	30796290
Pubmed	Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy.	CD109 HDAC1	2.52e-05	2	175	2	32938908
Pubmed	Sexual cues influence cocaine-induced locomotion, anxiety and the immunoreactivity of oestrogen receptor alpha and tyrosine hydroxylase in both sexes.	ESR1 TH	2.52e-05	2	175	2	31009113
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	NOP16 MPDZ RDX LMTK3 MADD MAP3K5 NCOR1 SYT11 A2ML1 HERC2 KCNT1	3.17e-05	475	175	11	31040226
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DMXL2 MPDZ IPO4 TRIP12 ITGB4 PSME4 KLHL12 ESPL1 PPP2R3C	4.01e-05	322	175	9	26514267
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KNTC1 MYH3 RARG PCDHGB1 PCDHGA5 RDX PSMD3 SPG11 CFAP210 SMC2 MINDY2 NDUFB4 TRIP12 PALB2 FER1L6 NCOR1 NRXN3 USPL1 HDAC1 ZNF292	4.22e-05	1442	175	20	35575683
Pubmed	Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation.	MAG NRG1 TH	4.38e-05	14	175	3	19179536
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH17 DNAH5	4.38e-05	14	175	3	9373155
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZXDC ASXL1 FBXL12 PSMD3 SKP2 TRIP12 KANSL2 COMMD1 OGA HDAC1 ZNF292	4.59e-05	495	175	11	27705803
Pubmed	p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.	PALB2 NFE2L1 NBR1	5.45e-05	15	175	3	30126895
Pubmed	Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.	DHX36 VPS13C PSMD3 HDAC1	6.56e-05	43	175	4	26030138
Pubmed	Asprosin-neutralizing antibodies as a treatment for metabolic syndrome.	CDH23 LEPR P2RX7	6.68e-05	16	175	3	33904407
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SUPT20H NOP16 ESR1 DHX38 POLR1C MPDZ DDX51 IPO4 NDUFB4 WDR3 ATP6V0D1 FAM83D CKAP2 HERC2 PATJ ZC3H7B HEATR5B HDAC1 ZNF574 SMG6	7.05e-05	1497	175	20	31527615
Pubmed	Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.	MAG ADGRV1 LOXHD1 HERC2	7.19e-05	44	175	4	27534441
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	DCAF1 LMTK2 MPDZ OXA1L EIF2B4 A2ML1 PATJ FRMD3	7.22e-05	270	175	8	24366813
Pubmed	Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1-Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy.	LEPR BSCL2	7.53e-05	3	175	2	31656096
Pubmed	Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter.	ESR1 NCOR1	7.53e-05	3	175	2	19147702
Pubmed	A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway.	PER2 SMG6	7.53e-05	3	175	2	36638184
Pubmed	Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.	MPDZ PATJ	7.53e-05	3	175	2	12403818
Pubmed	Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.	BCR ESPL1	7.53e-05	3	175	2	26087013
Pubmed	Repression of the estrogen receptor-alpha transcriptional activity by the Rho/megakaryoblastic leukemia 1 signaling pathway.	ESR1 MAP3K9	7.53e-05	3	175	2	19826002
Pubmed	Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.	ESR1 NCOR1	7.53e-05	3	175	2	15802375
Pubmed	Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.	MAP3K5 MAP3K9	7.53e-05	3	175	2	22197930
Pubmed	Mapping quantitative trait loci for hearing loss in Black Swiss mice.	CDH23 PCDH15	7.53e-05	3	175	2	16426780
Pubmed	Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons.	KCNT2 KCNT1	7.53e-05	3	175	2	26559620
Pubmed	ASK1 contributes to fibrosis and dysfunction in models of kidney disease.	LEPR MAP3K5	7.53e-05	3	175	2	30024858
Pubmed	Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.	RYR1 ITPR2	7.53e-05	3	175	2	23223241
Pubmed	Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy.	NCOR1 HDAC1	7.53e-05	3	175	2	29660306
Pubmed	Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.	CDH23 PCDH15	7.53e-05	3	175	2	17805295
Pubmed	Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway.	DUSP19 MAP3K5	7.53e-05	3	175	2	11959862
Pubmed	HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.	ESR1 CTSK	7.53e-05	3	175	2	24023068
Pubmed	Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.	MAP3K5 P2RX7	7.53e-05	3	175	2	18211888
Pubmed	A histone deacetylase corepressor complex regulates the Notch signal transduction pathway.	NCOR1 HDAC1	7.53e-05	3	175	2	9694793
Pubmed	Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.	FER1L6 FER1L4	7.53e-05	3	175	2	36696506
Pubmed	COPS5 amplification and overexpression confers tamoxifen-resistance in ERα-positive breast cancer by degradation of NCoR.	ESR1 NCOR1	7.53e-05	3	175	2	27375289
Pubmed	Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors.	MAG GNAT2	7.53e-05	3	175	2	3856323
Pubmed	Estrogen-independent role of ERα in ovarian cancer progression induced by leptin/Ob-Rb axis.	ESR1 LEPR	7.53e-05	3	175	2	31077012
Pubmed	GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome.	IFIH1 GPATCH3	7.53e-05	3	175	2	28414768
Interaction	TOP3B interactions	VWA5B2 ZXDC RARG TMC6 HECTD4 FBXL12 LMTK2 TRMT1 CUL9 ANKLE1 IPO4 BCR ITGB4 RYR1 TBC1D9 MADD MAP3K5 ITPR2 NCOR1 VAC14 FAT1 PSME4 PER2 ZMIZ2 TMEM132A HERC2 ZC3H7B ESPL1 PPP2R3C OGA DHX34 SMG6	8.01e-07	1470	172	32	int:TOP3B
Cytoband	Xp22.11	SUPT20HL1 ACOT9 SUPT20HL2	6.88e-05	21	175	3	Xp22.11
Cytoband	3q13.33	STXBP5L LRRC58 NDUFB4	2.05e-04	30	175	3	3q13.33
GeneFamily	Dyneins, axonemal	DNAH12 DNAH17 DNAH5 DNAH9	3.35e-06	17	114	4	536
GeneFamily	Potassium sodium-activated channel subfamily T	KCNT2 KCNT1	3.94e-05	2	114	2	856
GeneFamily	DEAH-box helicases	DHX36 DHX38 DHX34	1.29e-04	16	114	3	500
GeneFamily	Cadherin related	CDH23 FAT1 PCDH15	1.56e-04	17	114	3	24
GeneFamily	Ferlin family	FER1L6 FER1L4	5.81e-04	6	114	2	828
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 A2ML1	1.38e-03	9	114	2	1234
GeneFamily	PDZ domain containing\|Crumbs complex	MPDZ PATJ	1.38e-03	9	114	2	1223
GeneFamily	Proteasome	PSMD3 PSMD5 PSME4	2.51e-03	43	114	3	690
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 DMXL2 SMC2 TBC1D9 RAD54B FAM83D CKAP2 PATJ CTSK	7.91e-08	195	174	9	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	DHX36 VPS13C DDX60 OAS3 IFIH1 N4BP1 DDX60L OGA ZNF292	8.63e-08	197	174	9	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	DHX36 VPS13C DDX60 OAS3 IFIH1 N4BP1 DDX60L OGA ZNF292	9.01e-08	198	174	9	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DHX36 VPS13C DDX60 OAS3 IFIH1 N4BP1 DDX60L OGA ZNF292	9.01e-08	198	174	9	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 IDS LEPR TBC1D9 IQSEC1 PATJ CTSK	7.54e-07	187	174	8	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 IDS LEPR TBC1D9 IQSEC1 PATJ CTSK	7.54e-07	187	174	8	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	HECTD4 MINDY2 TRIP12 MADD FAM83D BSCL2 HEATR5B	6.56e-06	178	174	7	829ea00c022a78d1861aa3ec53503272976775d9
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	RSPH4A CFAP210 DNAH12 DNAH17 DNAAF1 DNAH5 DNAH9	6.56e-06	178	174	7	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	DDX60 OAS3 IFIH1 N4BP1 CCR7 DDX60L DNAH9	6.80e-06	179	174	7	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	7.86e-06	183	174	7	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DDX60 OAS3 TRIP12 IFIH1 N4BP1 DDX60L ZNF292	7.86e-06	183	174	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L ADGRV1 FAT1 LOXHD1 PCDH15 DNAH5 DNAH9	8.14e-06	184	174	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	8.14e-06	184	174	7	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L ADGRV1 FAT1 LOXHD1 PCDH15 DNAH5 DNAH9	8.14e-06	184	174	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L ADGRV1 FAT1 LOXHD1 PCDH15 DNAH5 DNAH9	8.14e-06	184	174	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 IDS LEPR TBC1D9 IQSEC1 PATJ CTSK	8.14e-06	184	174	7	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	8.14e-06	184	174	7	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	8.14e-06	184	174	7	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 IDS LEPR TBC1D9 IQSEC1 PATJ CTSK	8.44e-06	185	174	7	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RSPH4A CFAP210 DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	8.44e-06	185	174	7	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	8.74e-06	186	174	7	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 LEPR TBC1D9 IQSEC1 PATJ CTSK	8.74e-06	186	174	7	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	KNTC1 DMXL2 VPS13C ITPR2 USPL1 DOP1B ZNF292	8.74e-06	186	174	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	RSPH4A CFAP210 DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	9.05e-06	187	174	7	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MAG NRAP ADGRV1 ITGB4 FAM83D TDRD6	9.39e-06	124	174	6	9f169fa17be1842a6bd83778ff30465a740edd5f
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	NRG1 BCR LEPR ITPR2 NRXN3 KCNT2 PCDH15	9.70e-06	189	174	7	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	MAP3K5 GTF2E1 VAC14 USP38 SYT11 ZC3H7B ZNF574	1.00e-05	190	174	7	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	NRG1 BCR ITGB4 LEPR ITPR2 KCNT2 PCDH15	1.07e-05	192	174	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	DDX60 OAS3 IFIH1 N4BP1 DDX60L OGA ZNF292	1.11e-05	193	174	7	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RSPH4A CFAP210 DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	1.15e-05	194	174	7	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 SMC2 TBC1D9 RAD54B CKAP2 PATJ CTSK	1.15e-05	194	174	7	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWA5B2 MPDZ CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	1.27e-05	197	174	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RSPH4A CFAP210 VILL A2ML1 DNAAF1 DNAH5 DNAH9	1.40e-05	200	174	7	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	VPS13C DDX60 OAS3 TRIP12 IFIH1 DDX60L ZNF292	1.40e-05	200	174	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KNTC1 SMC2 P2RX7 RAD54B FAM83D CKAP2 ESPL1	1.40e-05	200	174	7	203b9a5de4430713da01b3331e69381db449a3a0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KNTC1 SMC2 P2RX7 RAD54B FAM83D CKAP2 ESPL1	1.40e-05	200	174	7	a854e19703dc920e48304541e2b06ed013292f3e
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RSPH4A CFAP210 VILL A2ML1 DNAAF1 DNAH5 DNAH9	1.40e-05	200	174	7	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal\|6m / Sample Type, Dataset, Time_group, and Cell type.	MYH3 RSPH4A CFAP210 RYR1 DNAH12 TRPM1 DNAAF1	1.40e-05	200	174	7	13ec8afea86e4a10599c924871ba4e325b0a8013
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	RSPH4A PRR22 FBP2 PALB2 PATJ GPAT2	2.87e-05	151	174	6	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP210 DNAH12 PATJ DNAAF1 DNAH5 DNAH9	2.87e-05	151	174	6	8216462e723fec2797387929dde095370947e10a
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	RSPH4A PRR22 FBP2 PALB2 PATJ GPAT2	2.87e-05	151	174	6	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	DDX60 AMZ1 OAS3 IFIH1 CCR7 DDX60L	2.98e-05	152	174	6	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYBU CYP39A1 DNAH12 PATJ DNAAF1 DNAH5	3.21e-05	154	174	6	ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OAS3 FBP2 TBC1D9 CLIC2 RIMS4 TMEM132A	3.58e-05	157	174	6	e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OAS3 FBP2 TBC1D9 CLIC2 RIMS4 TMEM132A	3.71e-05	158	174	6	e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCell	Ciliated_cells-A-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	VWA5B2 STXBP5L CFAP210 DNAH12 DNAAF1 DNAH9	4.72e-05	165	174	6	0ebdbbdb151fb797335013d5838af1c7bbc45b06
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	DCAF1 ZXDC HECTD4 INTS3 OGA SLFNL1	4.88e-05	166	174	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	COVID-19_Severe-CD4+_T_activated\|COVID-19_Severe / Disease condition and Cell class	DDX60 OAS3 IFIH1 CCR7 DDX60L PATJ	4.88e-05	166	174	6	0f138dbafad6f83975944e8f6398411127b150cc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STXBP5L RYR1 PCDH15 TRPM1 PATJ DNAH9	5.05e-05	167	174	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MYH3 DUSP19 SKP2 ITPR2 MAP3K9 CCR7	5.22e-05	168	174	6	c51244b4bdbfd961e2725306aa9cb25dd66d58bd
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ARRDC1 MPDZ ITPR2 WDR3 NCOR1 SYT11	5.39e-05	169	174	6	b66ffc2b2b6bfcc3a6e639d9d31d3de95f4a94e1
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH4A ADGRV1 NRXN3 PCDH15 DNAH5 DNAH9	5.39e-05	169	174	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKLE1 SMC2 P2RX7 CCR7 CKAP2 ESPL1	5.57e-05	170	174	6	2d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell	Ciliated_cells-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	VWA5B2 CFAP210 FER1L6 DNAH12 DNAAF1 DNAH5	5.57e-05	170	174	6	8b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ANKLE1 SMC2 FAM83D CKAP2 ESPL1	5.95e-05	172	174	6	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKLE1 SMC2 LEPR PALB2 FER1L4 CKAP2	6.97e-05	177	174	6	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	7.41e-05	179	174	6	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 STXBP5L TBC1D9 NRXN3 PATJ FRMD3	7.64e-05	180	174	6	d76349ecef7c5878bf215e946f032264161eb61b
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRTAC1 ADGRV1 FAT1 NRXN3 PATJ DNAH5	7.64e-05	180	174	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	7.64e-05	180	174	6	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 ANKLE1 SMC2 FAM83D CKAP2 ESPL1	7.88e-05	181	174	6	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 ANKLE1 SMC2 FAM83D CKAP2 ESPL1	7.88e-05	181	174	6	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 AMZ1 TBC1D9 MADD IQSEC1 CTSK	8.12e-05	182	174	6	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Deuterosomal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RSPH4A CFAP210 DNAH12 DNAH17 DNAAF1 DNAH9	8.12e-05	182	174	6	000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	8.12e-05	182	174	6	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	DDX60 OAS3 IFIH1 CCR7 PATJ OGA	8.12e-05	182	174	6	877b6e611626628e709568747512f2827ebb2795
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH3 STXBP5L ADGRV1 SMC2 SKP2 CKAP2	8.12e-05	182	174	6	e6968e0bd9cef92052d04ac54e2dd746b37623f6
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	8.12e-05	182	174	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DDX60 OAS3 IFIH1 CCR7 DDX60L FRMD3	8.37e-05	183	174	6	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 ANKLE1 TBC1D9 FAM83D CKAP2 CTSK	8.37e-05	183	174	6	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 ANKLE1 SMC2 SKP2 RAD54B ESPL1	8.37e-05	183	174	6	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 RSPH4A SEZ6L2 SYT11 DNAH9 KCNT1	8.63e-05	184	174	6	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM3B SYBU LMTK3 VILL FAM83D GNAT2	8.63e-05	184	174	6	c2ca984551baf4becbefbe58bd1889828542b045
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 ANKLE1 SMC2 SKP2 RAD54B ESPL1	8.89e-05	185	174	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AMZ1 ANKLE1 SMC2 TBC1D9 FAM83D CKAP2	8.89e-05	185	174	6	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG DMXL2 AMZ1 TBC1D9 IQSEC1 CTSK	8.89e-05	185	174	6	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KNTC1 DMXL2 VPS13C USPL1 DOP1B ZNF292	8.89e-05	185	174	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	15-Airway-Epithelial-Multiciliated_cell\|Airway / Age, Tissue, Lineage and Cell class	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	8.89e-05	185	174	6	0998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 SMC2 RAD54B CKAP2 PATJ CTSK	8.89e-05	185	174	6	b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	8.89e-05	185	174	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	P28-Epithelial-airway_epithelial_cell-club_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RSPH4A DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	9.16e-05	186	174	6	a26811481668fa25c48a064a56c198685693ad8d
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RSPH4A MPDZ CFAP210 DNAH12 DNAH5 DNAH9	9.16e-05	186	174	6	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	P28-Epithelial-airway_epithelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RSPH4A DNAH12 KNDC1 DNAAF1 DNAH5 DNAH9	9.16e-05	186	174	6	df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCell	18-Distal-Epithelial-Multiciliated_cell\|Distal / Age, Tissue, Lineage and Cell class	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	8d7fa6b2950898e7f283401808378ba2a41b9651
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH4A CCDC154 KNDC1 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L EMILIN3 NRXN3 LRRC3B TMEM132A PATJ	9.43e-05	187	174	6	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH4A CCDC154 KNDC1 DNAAF1 DNAH5 DNAH9	9.43e-05	187	174	6	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DDX60 OAS3 IFIH1 N4BP1 CCR7 DDX60L	9.71e-05	188	174	6	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 LMTK3 TBC1D9 NRXN3 PATJ FRMD3	9.71e-05	188	174	6	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	82c006f43c93f4a867953a446864f02b44536a23
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A CFAP210 DNAH12 DNAAF1 DNAH5 DNAH9	9.71e-05	188	174	6	606907c865bd2f11bb6474932716550f7723d858
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ANKLE1 SMC2 RAD54B FAM83D CKAP2	9.71e-05	188	174	6	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 AMZ1 TBC1D9 IQSEC1 PATJ CTSK	1.00e-04	189	174	6	98f517af255ef234eefc3ed7e6c1d63331ab8af0
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	DCAF1 RARG SYBU ITGB4 IFIH1 HPS1 N4BP1 CCR7 PATJ ZNF292	2.43e-06	195	172	10	6224_UP
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; PC3; HT_HG-U133A	MINDY2 TBC1D9 MADD IFIH1 PSME4 HPS1 TMEM132A ZC3H7B DHX34 ZNF574	2.66e-06	197	172	10	1801_DN
Drug	carbohydrazide	RDX GTF2E1 P2RX7 CTSK	1.39e-05	20	172	4	CID000073948
Drug	15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A	NOP16 TMC6 IPO4 MINDY2 MAP3K5 BBS10 WDR3 THBS4 DOP1B	1.48e-05	190	172	9	1172_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZXDC ESR1 TMC6 CUL9 SKP2 IFIH1 HPS1 DHX34 CTSK	1.54e-05	191	172	9	5210_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A	SUPT20H ESR1 MPDZ CYP39A1 SYT11 HPS1 MAP3K9 DNAAF1 DHX34	1.82e-05	195	172	9	1214_UP
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	DCAF1 SUPT20H ESR1 TMC6 OAS3 IDS CCR7 OGA DHX34	1.82e-05	195	172	9	6967_UP
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	STXBP5L ESR1 IDS SKP2 ITGB4 TBC1D9 HPS1 TMEM132A OGA	1.97e-05	197	172	9	3825_DN
Drug	Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A	DCAF1 ZXDC TMC6 SKP2 LEPR RAD54B PATJ DHX34 CTSK	1.97e-05	197	172	9	7478_DN
Drug	Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	DMXL2 RARG ESR1 HLCS SKP2 ITGB4 N4BP1 PATJ ZC3H7B	2.14e-05	199	172	9	2802_DN
Drug	Khellin [82-02-0]; Up 200; 15.4uM; PC3; HG-U133A	ASXL1 RARG DHX38 HLCS TRMT1 PSMD3 ITGB4 ESPL1 ZNF574	2.23e-05	200	172	9	1922_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A	DCAF1 ESR1 MPDZ SEZ6L2 TBC1D9 ITPR2 DNAH17 ZC3H7B DHX34	2.23e-05	200	172	9	3081_UP
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A	NOP16 TRMT1 SYBU TBC1D9 WDR3 RAD54B DNAAF1 DHX34	6.99e-05	180	172	8	5202_DN
Drug	Propofol [2078-54-8]; Up 200; 22.4uM; MCF7; HT_HG-U133A	DDX60 CUL9 OAS3 SYBU MAP3K5 IFIH1 MAP3K9 DHX34	6.99e-05	180	172	8	5306_UP
Drug	Lanatoside C [17575-22-3]; Down 200; 4uM; MCF7; HT_HG-U133A	ZXDC SUPT20H SYBU SKP2 PALB2 WDR3 GTF2E1 N4BP1	7.85e-05	183	172	8	3963_DN
Drug	Digitoxigenin [143-62-4]; Down 200; 10.6uM; HL60; HT_HG-U133A	ZXDC SUPT20H NOP16 SKP2 PALB2 WDR3 GTF2E1 PSME4	8.79e-05	186	172	8	1339_DN
Drug	Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	DDX60 OAS3 DOK2 SKP2 LEPR IFIH1 CLIC2 ZC3H7B	9.13e-05	187	172	8	5025_UP
Drug	Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A	ESR1 DDX51 BCR SKP2 LEPR HPS1 N4BP1 OGA	9.83e-05	189	172	8	2832_UP
Drug	ICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A	HLCS ITGB4 TBC1D9 ZMIZ2 HPS1 N4BP1 DHX34 SMG6	1.10e-04	192	172	8	4462_DN
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	SUPT20H RARG ESR1 MAP3K5 IFIH1 NCOR1 ZMIZ2 OGA	1.14e-04	193	172	8	4315_DN
Drug	Thiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ZXDC RARG ESR1 HLCS SYBU NCOR1 HPS1 DNAAF1	1.14e-04	193	172	8	7033_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	ZXDC RARG ESR1 PALB2 MAP3K5 HPS1 DHX34 CTSK	1.14e-04	193	172	8	6985_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	RARG HLCS IDS SKP2 ITGB4 IFIH1 ZMIZ2 ZC3H7B	1.14e-04	193	172	8	4338_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	IDS BCR HPS1 N4BP1 GNAT2 PATJ OGA DHX34	1.18e-04	194	172	8	5641_DN
Drug	rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A	DCAF1 NOP16 LMTK2 ITPR2 WDR3 NRXN3 N4BP1 DHX34	1.22e-04	195	172	8	5980_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A	DMXL2 ESR1 TMC6 ITGB4 THAP9 ITPR2 N4BP1 ZC3H7B	1.22e-04	195	172	8	2855_UP
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A	ESR1 MINDY2 SKP2 ITGB4 HPS1 ZC3H7B DNAAF1 OGA	1.22e-04	195	172	8	6799_DN
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TMC6 LMTK2 SKP2 ITPR2 PER2 HPS1 N4BP1 SMG6	1.22e-04	195	172	8	3893_DN
Drug	Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	DMXL2 CUL9 F9 ZMIZ2 GNAT2 ZC3H7B OGA DHX34	1.22e-04	195	172	8	3327_UP
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	RARG VPS13C ESR1 TMC6 IFIH1 HPS1 DNAAF1 DHX34	1.22e-04	195	172	8	2311_DN
Drug	monastrol; Down 200; 100uM; MCF7; HG-U133A	ASXL1 NOP16 ESR1 CRTAC1 BCR VAC14 GPATCH3 ZC3H7B	1.22e-04	195	172	8	681_DN
Drug	Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A	SUPT20H DHX38 CUL9 IDS BCR MINDY2 SEZ6L2 NCOR1	1.26e-04	196	172	8	2056_DN
Drug	Calycanthine [595-05-1]; Down 200; 11.6uM; HL60; HG-U133A	NOP16 TRMT1 RDX IDS PPM1B NCOR1 NFE2L1 ZNF292	1.26e-04	196	172	8	1771_DN
Drug	Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A	C14orf93 ESR1 HLCS CUL9 MAP3K5 IFIH1 HPS1 RAD54B	1.26e-04	196	172	8	7348_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	RARG TMC6 HLCS CUL9 ITGB4 NCOR1 HPS1 PATJ	1.26e-04	196	172	8	7356_DN
Drug	Proguanil hydrochloride [637-32-1]; Down 200; 13.8uM; HL60; HT_HG-U133A	DCAF1 IDS PER2 DNAH17 HPS1 ZC3H7B DHX34 ZNF574	1.26e-04	196	172	8	2944_DN
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HT_HG-U133A	SUPT20H FAM13C IDS CYP39A1 NRXN3 PSME4 HPS1 PATJ	1.26e-04	196	172	8	4683_DN
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A	DDX60 TMC6 MPDZ CUL9 PSME4 ZC3H7B ZNF574 ZNF292	1.26e-04	196	172	8	2108_DN
Drug	Tetracaone hydrochloride [136-47-0]; Down 200; 13.2uM; MCF7; HT_HG-U133A	C14orf93 ESR1 LEPR RYR1 TH GPATCH3 HPS1 MAP3K9	1.26e-04	196	172	8	2888_DN
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	C14orf93 OAS3 F9 ITPR2 N4BP1 GNAT2 OGA ZNF292	1.26e-04	196	172	8	5624_DN
Drug	Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; HL60; HT_HG-U133A	NRG1 LMTK2 MPDZ SEZ6L2 DNAH17 CCR7 DNAAF1 DHX34	1.26e-04	196	172	8	2741_UP
Drug	AH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A	DMXL2 RARG ESR1 HLCS ITGB4 HPS1 ZC3H7B DHX34	1.31e-04	197	172	8	6890_UP
Drug	Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TMC6 SKP2 ITGB4 NCOR1 N4BP1 PATJ OGA DHX34	1.31e-04	197	172	8	6819_DN
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	DCAF1 RARG ESR1 LEPR ITPR2 SYT11 DNAH17 DOP1B	1.31e-04	197	172	8	3719_UP
Drug	Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; HL60; HT_HG-U133A	SKP2 SEZ6L2 ITGB4 TBC1D9 RAD54B ZC3H7B OGA ZNF574	1.31e-04	197	172	8	3055_DN
Drug	Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A	DMXL2 DDX60 MINDY2 PER2 DNAAF1 OGA LILRA4 DOP1B	1.31e-04	197	172	8	5250_UP
Drug	Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	ESR1 TMC6 OAS3 LEPR GPATCH3 HPS1 ZC3H7B DNAAF1	1.31e-04	197	172	8	3438_UP
Drug	Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A	RARG VPS13C SYBU RYR1 MAP3K5 NCOR1 OGA DHX34	1.31e-04	197	172	8	6211_UP
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	RARG OAS3 IDS ITGB4 N4BP1 PATJ ZC3H7B DHX34	1.36e-04	198	172	8	1491_DN
Drug	sodium 4-phenylbutyrate; Down 200; 1000uM; MCF7; HG-U133A	RARG ESR1 CUL9 LEPR VAC14 HPS1 N4BP1 DHX34	1.36e-04	198	172	8	407_DN
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA	RARG TMC6 TRMT1 BCR SKP2 TBC1D9 MAP3K5 NCOR1	1.36e-04	198	172	8	1073_DN
Drug	Methimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A	ESR1 SKP2 ITPR2 VAC14 NRXN3 SYT11 ZMIZ2 DHX34	1.36e-04	198	172	8	4550_DN
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A	SUPT20H RARG DDX60 ESR1 HLCS SKP2 PATJ DHX34	1.36e-04	198	172	8	6657_DN
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A	ESR1 IDS ITPR2 VAC14 ZMIZ2 IQSEC1 ZC3H7B DOP1B	1.36e-04	198	172	8	2197_UP
Drug	Azapropazone [13539-59-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A	RARG CUL9 ITPR2 CLIC2 PATJ OGA DHX34 SMG6	1.36e-04	198	172	8	6522_UP
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; PC3; HT_HG-U133A	ESR1 HLCS ZMIZ2 HPS1 MAP3K9 PATJ ZC3H7B ZNF292	1.36e-04	198	172	8	6304_UP
Drug	Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; PC3; HT_HG-U133A	SUPT20H HLCS TH NRXN3 MAP3K9 CCR7 DNAAF1 ZNF292	1.36e-04	198	172	8	6315_UP
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A	C14orf93 SUPT20H HLCS ITPR2 ZMIZ2 HPS1 PATJ DHX34	1.36e-04	198	172	8	3756_DN
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SYBU ITGB4 TH ZMIZ2 HPS1 PATJ DNAAF1 ZNF574	1.40e-04	199	172	8	3344_DN
Drug	Ethionamide [536-33-4]; Down 200; 24uM; PC3; HT_HG-U133A	ZXDC HLCS DDX51 ZMIZ2 HPS1 RAD54B ZC3H7B OGA	1.40e-04	199	172	8	4593_DN
Drug	Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A	OAS3 SYBU MADD NCOR1 TH ZMIZ2 PATJ DHX34	1.40e-04	199	172	8	5426_DN
Drug	Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; HL60; HG-U133A	DMXL2 RARG DDX60 ESR1 DHX38 DOK2 MAP3K9 N4BP1	1.40e-04	199	172	8	1991_UP
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	ESR1 SKP2 ITPR2 VAC14 NFE2L1 RAD54B ZC3H7B ZNF292	1.45e-04	200	172	8	3465_DN
Drug	S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; MCF7; HT_HG-U133A	HLCS CUL9 SYBU ITGB4 HPS1 RAD54B MAP3K9 DHX34	1.45e-04	200	172	8	5311_UP
Drug	fullerene C60	VWA5B2 DCAF1 ZXDC DHX36 MYH3 VPS11 PCDHGA5 HLCS TRMT1 SYBU CFAP210 SKP2 NCOR1 THBS4 ATP6V0D1 PER2 VILL ZMIZ2 DNAH17 HPS1 DNAAF1 CTSK NBR1 HDAC1 ZNF574	1.57e-04	1498	172	25	ctd:C069837
Disease	lymphocyte count	GALM PCDHGB1 PCDHGA5 AMZ1 HECTD4 CDH23 PSMD3 DOK2 BCR TRIP12 LEPR ITPR2 IFIH1 NCOR1 KANSL2 PSME4 SYT11 DNAH17 CCR7 DDX60L ZC3H7B PPP2R3C SMG6	1.12e-05	1464	169	23	EFO_0004587
Disease	Usher syndrome, type 1D	CDH23 PCDH15	3.26e-05	2	169	2	C2931208
Disease	USHER SYNDROME, TYPE ID	CDH23 PCDH15	3.26e-05	2	169	2	C1832845
Disease	USHER SYNDROME, TYPE ID	CDH23 PCDH15	3.26e-05	2	169	2	601067
Disease	Otitis Media	RSPH4A A2ML1	3.26e-05	2	169	2	C0029882
Disease	Usher syndrome type 1D	CDH23 PCDH15	3.26e-05	2	169	2	cv:C1832845
Disease	Usher syndrome type 1D (is_implicated_in)	CDH23 PCDH15	3.26e-05	2	169	2	DOID:0110831 (is_implicated_in)
Disease	Ciliopathies	CDH23 ADGRV1 BBS10 PCDH15 DNAAF1 DNAH5	4.23e-05	110	169	6	C4277690
Disease	Neoplasm of uncertain or unknown behavior of breast	ESR1 PALB2 NCOR1 HERC2	8.91e-05	41	169	4	C0496956
Disease	Breast adenocarcinoma	ESR1 PALB2 NCOR1 HERC2	8.91e-05	41	169	4	C0858252
Disease	Nonsyndromic Deafness	CDH23 RDX ADGRV1 LOXHD1 PCDH15	1.05e-04	81	169	5	C3711374
Disease	Primary Ciliary Dyskinesia	RSPH4A DNAAF1 DNAH5 DNAH9	1.53e-04	47	169	4	C4551720
Disease	Multiple pterygium syndrome	MYH3 RYR1	1.94e-04	4	169	2	C0265261
Disease	age-related macular degeneration, cataract, glaucoma	PCDHGA5 HERC2	1.94e-04	4	169	2	EFO_0001365, MONDO_0005041, MONDO_0005129
Disease	C-reactive protein measurement	DPYD DMXL2 VPS13C CRTAC1 SPG11 INTS3 TRIP12 LEPR MADD NCOR1 COMMD1 P2RX7 ZMIZ2 DNAH17 EIF2B4 PCDH15 GNAT2 PATJ	2.04e-04	1206	169	18	EFO_0004458
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	CDH23 RDX LOXHD1 PCDH15	2.10e-04	51	169	4	cv:CN043650
Disease	susceptibility to bacterial meningitis measurement	NRG1 STXBP5L AMZ1 DNAH5	2.27e-04	52	169	4	EFO_0008411
Disease	hearing impairment	CDH23 RDX ADGRV1 LOXHD1 PCDH15	2.57e-04	98	169	5	C1384666
Disease	Bronchiectasis	RSPH4A DNAAF1 DNAH5	2.62e-04	22	169	3	C0006267
Disease	specific language impairment	ESR1 HLCS	3.22e-04	5	169	2	EFO_1001510
Disease	Usher syndrome, type 1A	CDH23 PCDH15	3.22e-04	5	169	2	C2931205
Disease	USHER SYNDROME, TYPE IB (disorder)	CDH23 PCDH15	3.22e-04	5	169	2	C1848638
Disease	USHER SYNDROME, TYPE IA, FORMERLY	CDH23 PCDH15	3.22e-04	5	169	2	C1848639
Disease	USHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY	CDH23 PCDH15	3.22e-04	5	169	2	C1848640
Disease	Usher syndrome type 1	CDH23 PCDH15	3.22e-04	5	169	2	cv:C1568247
Disease	executive function measurement	DMXL2 ESR1 POLR1C CUL9 RYR1 NRXN3 RIMS4 PCDH15 OGA	3.36e-04	376	169	9	EFO_0009332
Disease	body weight	KNTC1 NRG1 DPYD CACUL1 VPS13C AMZ1 ESR1 HECTD4 CRTAC1 ADGRV1 TRIP12 NCOR1 NRXN3 DNAH12 ZMIZ2 PCDH15 GNAT2 PATJ	3.48e-04	1261	169	18	EFO_0004338
Disease	methionine measurement	SYBU ADGRV1 PCDH15	4.36e-04	26	169	3	EFO_0009771
Disease	Usher Syndrome, Type I	CDH23 PCDH15	4.82e-04	6	169	2	C1568247
Disease	Myeloid Leukemia, Chronic	ASXL1 BCR PER2	6.04e-04	29	169	3	C0023473
Disease	Hereditary retinal dystrophy	CDH23 PCDH15	6.72e-04	7	169	2	C0154860
Disease	Delayed Puberty	LEPR BSCL2	6.72e-04	7	169	2	C0034012
Disease	Usher syndrome	CDH23 PCDH15	6.72e-04	7	169	2	cv:C0271097
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	FER1L6 FER1L4	6.72e-04	7	169	2	DOID:11724 (implicated_via_orthology)
Disease	Lung Neoplasms	NRG1 DPYD ESR1 DOK2 IDS SMC2 IQSEC1	8.73e-04	265	169	7	C0024121
Disease	Malignant neoplasm of lung	NRG1 DPYD ESR1 DOK2 IDS SMC2 IQSEC1	8.92e-04	266	169	7	C0242379
Disease	Nonsyndromic genetic hearing loss	CDH23 RDX LOXHD1 PCDH15	9.67e-04	76	169	4	cv:C5680182
Disease	Lung diseases	RSPH4A HPS1 DNAAF1 DNAH5	1.07e-03	78	169	4	C0024115
Disease	Primary ciliary dyskinesia	RSPH4A DNAAF1 DNAH5	1.15e-03	36	169	3	cv:C0008780
Disease	body weights and measures	DPYD CACUL1 MAP3K9	1.34e-03	38	169	3	EFO_0004324
Disease	Short Stature, CTCAE	RSPH4A IQSEC1	1.42e-03	10	169	2	C2919142
Disease	Short stature	RSPH4A IQSEC1	1.42e-03	10	169	2	C0349588
Disease	Disorder of eye	CDH23 ADGRV1 BBS10 PCDH15 TRPM1 GNAT2	1.44e-03	212	169	6	C0015397
Disease	microfibrillar-associated protein 2 measurement	NRG1 A2ML1	1.73e-03	11	169	2	EFO_0801801
Disease	Oligospermia	ESR1 BSCL2	2.07e-03	12	169	2	C0028960
Disease	triacylglycerol 58:12 measurement	TRIP12 NRXN3	2.07e-03	12	169	2	EFO_0010439
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 OAS3	2.07e-03	12	169	2	EFO_0004329, EFO_0007878
Disease	Malignant neoplasm of salivary gland	ITGB4 FAT1 ESPL1	2.20e-03	45	169	3	C0220636
Disease	Heart Diseases	RARG TH HDAC1	2.34e-03	46	169	3	C0018799
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	DMXL2 CDH23	2.44e-03	13	169	2	C1846647
Disease	Cardiotoxicity	NRG1 RARG	2.44e-03	13	169	2	C0876994
Disease	Salivary Gland Neoplasms	ITGB4 FAT1 ESPL1	2.49e-03	47	169	3	C0036095
Disease	obesity	NRG1 CACUL1 LEPR FAT1 NRXN3 GNAT2	2.73e-03	241	169	6	EFO_0001073
Disease	smoking cessation	ASXL1 DPYD LEPR NRXN3 ZMIZ2 PCDH15 ZC3H7B	2.78e-03	325	169	7	EFO_0004319
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	DPYD EIF2B4	2.84e-03	14	169	2	C1858991
Disease	Mood Disorders	ESR1 TH P2RX7 BSCL2 HDAC1	2.88e-03	168	169	5	C0525045
Disease	Situs ambiguus	DNAH5 DNAH9	3.26e-03	15	169	2	C0266642
Disease	Influenza	DDX60 OAS3 IFIH1	3.32e-03	52	169	3	C0021400
Disease	Malignant neoplasm of breast	NRG1 DPYD RARG ESR1 CD109 HLCS LEPR PALB2 NCOR1 KCNT2 PER2 LRRC3B HERC2 DNAH9	3.64e-03	1074	169	14	C0006142
Disease	Breast Carcinoma	NRG1 DPYD ESR1 CD109 LEPR PALB2 NCOR1 LRRC3B HERC2	3.98e-03	538	169	9	C0678222
Disease	Astrocytosis	ITGB4 LEPR	4.19e-03	17	169	2	C3887640
Disease	Gliosis	ITGB4 LEPR	4.19e-03	17	169	2	C0017639
Disease	cytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant	CDH23 COMMD1	5.23e-03	19	169	2	EFO_0007044, EFO_0020106
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAH17 DNAH9	5.23e-03	19	169	2	DOID:10003 (implicated_via_orthology)
Disease	Colorectal Neoplasms	DPYD CACUL1 CD109 FAT1 LRRC3B ZNF292	5.37e-03	277	169	6	C0009404
Disease	velopharyngeal dysfunction	MPDZ ITPR2 PCDH15 LILRA4	5.40e-03	122	169	4	EFO_0009336
Disease	cutaneous melanoma, hair color	ADGRV1 BCR HERC2	5.45e-03	62	169	3	EFO_0000389, EFO_0003924
Disease	smoking behavior, body mass index	DMXL2 NRXN3 GNAT2 PATJ	5.56e-03	123	169	4	EFO_0004318, EFO_0004340
Disease	hematocrit	NRG1 AMZ1 DHX38 TMC6 HECTD4 HLCS ADGRV1 ITPR2 TH VAC14 FAT1 NFE2L1 ZMIZ2	5.62e-03	1011	169	13	EFO_0004348

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESFIYDIPTDLLPDI	SYT11	361	Q9BT88
VLLLPVVSFALYPEE	CTSK	6	P43235
VPLYKDPDDDLTLLI	SMG6	1076	Q86US8
FTYLLLDPRETQDLP	ANKLE1	451	Q8NAG6
IYLQPIDLSEEPVGS	AMZ1	96	Q400G9
LLYFLQLEAIPAPDS	BCR	1246	P11274
ALSPAIAEELPNYLV	A2ML1	11	A8K2U0
KNITIYSLPDEIPEE	ADGRV1	956	Q8WXG9
IPETDEPFYIILLNS	ADGRV1	1081	Q8WXG9
ATVLSIPELLYSDLQ	CCR7	186	P32248
SYIEVLLPLGSEPEL	ACOT9	86	Q9Y305
LPLFYTPIDLVDISV	DPYD	521	Q12882
LAPYAVPSELVLVEE	ACSF3	541	Q4G176
LVYSQPLDLPESVEV	DMXL2	976	Q8TDJ6
SNLVIPDVELETYIP	BBS10	491	Q8TAM1
SPEPLSLEELSERYE	CCDC154	36	A6NI56
LDLVPPGYVQLEDSS	CDH23	2336	Q9H251
YILSPLNLNSIPDIE	ARRDC1	131	Q8N5I2
IPDSLLLASTEYQPR	ASXL1	1076	Q8IXJ9
NILPPAVESELSEYA	CACUL1	311	Q86Y37
EPITSPIENIIAIYE	CKAP2	471	Q8WWK9
VDVDTYLTSQLPPLR	NFE2L1	26	Q14494
IYEEPIILSREPSAS	RAD54B	491	Q9Y620
SPDSYELSPQLEELI	RARG	176	P13631
VVEEPVDITPYLDQL	INTS3	561	Q68E01
PIDPEDLDLTLYLVV	PCDHGA5	681	Q9Y5G8
SVLVDVLYSPELLFP	ITPR2	1626	Q14571
SLPASPLRIVEDEEY	NRG1	511	Q02297
SDLENYILELIPTLP	PPP2R3C	191	Q969Q6
LNDEIYCPPETAVLL	RDX	111	P35241
LTPVDPTALLDYREV	ANKAR	86	Q7Z5J8
IEESIYPPAILPLEI	FAT1	3536	Q14517
PPTLDSIITEYLREQ	DCAF1	1001	Q9Y4B6
QEVPSVLAYALDISP	PAQR7	206	Q86WK9
PPQLLADPLYDSIEE	DOK2	321	O60496
DPLELVVTAYSRPTL	LILRA4	111	P59901
ASAEQLLLAPTPYII	MADD	361	Q8WXG6
YESELQLELPAVSPE	MAG	371	P20916
PLPQYTSLAEDLRLS	NRAP	1141	Q86VF7
TAVALDTEIPNELPY	HDAC1	316	Q13547
QYLEPDQEIVTIPDL	HERC2	1281	O95714
RENISPDYPLTLLEG	DOP1B	1571	Q9Y3R5
PSVGEIPQSELILYL	DOP1B	2136	Q9Y3R5
YIDEEELSPPLPLSQ	IQSEC1	306	Q6DN90
LIELDYSGRLEPSVP	FER1L4	891	A9Z1Z3
EPSDIVYLIRSDPLA	KCNT1	1186	Q5JUK3
RELLPVDESYVLPQS	LOXHD1	931	Q8IVV2
SLPDVYILPLAEVSL	LMTK3	96	Q96Q04
PALTPLYLLSAAEEI	HLCS	381	P50747
PDLTLSPRESIQLYD	DDX60	1021	Q8IY21
PDLTLTPQESIQLYD	DDX60L	1001	Q5H9U9
PLILGSPEDVQEYLT	FBP2	316	O00757
LISTIYDEPLPQDQT	GPATCH3	476	Q96I76
IPYEEDIPSLGLSEV	PER2	1221	O15055
VSALLDAEPPILYSE	ESR1	316	P03372
DLEPRELLSYVSVSP	PCDHGB1	491	Q9Y5G3
YELGLSNEEPVSIPL	PDPR	246	Q8NCN5
YFPEQSDLEPPLLEL	FAM83D	101	Q9H4H8
IALLELDEPLVLNSY	F9	316	P00740
DIVLLPLPTAYELDS	NRXN3	1511	Q9Y4C0
NLLQSYLTDPVSDPE	DNAH12	2616	Q6ZR08
LLYVLPEVLEDSPLV	LEPR	161	P48357
PVIYELISSLVPLAE	KNTC1	1211	P50748
LTTVEDPYLFELPAL	LRRC37B	666	Q96QE4
SNLELDYPPALLTTD	LMTK2	561	Q8IWU2
DLPPETVLLYLDSNQ	LRRC3B	61	Q96PB8
SYILINPSPDTRIEL	KCNT2	1081	Q6UVM3
LTVSDPIYILPLAVT	OXA1L	256	Q15070
ILTPSPITYGEEQLL	HECTD4	3686	Q9Y4D8
NLVYDVTPPELVDLV	EIF2B4	486	Q9UI10
YLLAELIPDAPLSSA	FAM3B	26	P58499
EVFEPLESPVDLYIL	ITGB4	121	P16144
LRTLPETLDPAEYNI	NDUFB4	11	O95168
TYDPPTLLELAARTI	LRRC58	256	Q96CX6
SILLYTPLNTVAPDD	PALB2	701	Q86YC2
TYQAAIPELRTPEEL	PCDH15	281	Q96QU1
LLLYQEPLLALDVDS	P2RX7	526	Q99572
IEADTYLPVDETLIP	GALM	196	Q96C23
YLPVDETLIPTGEVA	GALM	201	Q96C23
KEEPLTISELVYNPS	FRMD3	436	A2A2Y4
PSLPLNSADEIYELR	CD109	91	Q6YHK3
PSLLDEILAQAYTLL	ESPL1	1216	Q14674
ALLVPTLISYLLDEN	HEATR5B	1976	Q9P2D3
DTLIVDVYPVLDTPA	GRID2IP	426	A4D2P6
LLTPRYITDVIDAEP	KLHL12	226	Q53G59
LLYGDISPTPVDQLI	DNAH17	96	Q9UFH2
PLVPRYEEALSQLEE	DDX51	641	Q8N8A6
SLLDDYQLPEILRTP	DHX36	621	Q9H2U1
SEAAPLLNPLVDDYV	C14orf93	191	Q9H972
PDALLVPVAVTYDLV	GPAT2	321	Q6NUI2
IQVEPVLDYLTFLPA	IFIH1	26	Q9BYX4
TEELLRSQLYPEVPP	COMMD1	31	Q8N668
ELDYTSLPVLENLPT	DNAAF1	586	Q8NEP3
YLSAAELQPTESLPL	KANSL2	391	Q9H9L4
YVAEPTLEPRLSQDL	KNDC1	136	Q76NI1
EQLLQSYSEDPEPLL	CUL9	2036	Q8IWT3
LEILYPRDEDTLQDP	CRTAC1	526	Q9NQ79
PVEILNYIIPSGDLL	CYP39A1	351	Q9NYL5
PSPLTSLALLEEYVD	EMILIN3	291	Q9NT22
EAQLSLAIPELVFYP	DNAH9	921	Q9NYC9
LYPLENITLAPDPEV	IDS	241	P22304
ALILLVQDLYPSEST	HPS1	236	Q92902
YRVTLELELPESPVN	BSCL2	106	Q96G97
LIINAYPDNITPDTE	DCTN6	61	O00399
REPSLPQYEVLIVDE	DHX34	266	Q14147
PISLVPRLTLYSEAE	ERVFC1	356	P60507
ILSLQDLIIYFEPPS	RYR1	441	P21817
LLESEVPVITPYLSE	IPO4	231	Q8TEX9
YPPIQLLEIDFAELT	MAP3K9	131	P80192
LDDYLNTPLLDEIDP	CLIC2	146	O15247
EPTDYLTLANNPETL	DNAH5	236	Q8TE73
ETLPPVYALELLTIF	OAS3	221	Q9Y6K5
YLRSISLPVPVLVED	MAP3K5	961	Q99683
LAESPPLVVVELYDS	FER1L6	891	Q2WGJ9
YTPECIVFDLLDIPL	MINDY2	351	Q8NBR6
DYIEQEVGLPLLTPI	RSPH4A	581	Q5TD94
DVNLAYEILEPEPTE	GTF2E1	196	P29083
VLESVPDINLLDYLP	VAC14	201	Q08AM6
VLSVITEELPDVPLY	TRMT1	431	Q9NXH9
ALLDYLDAEELPPAL	SUPT20HL1	111	Q3ZLR7
DDLLPIPSDAYDVLL	TDRD6	1076	O60522
SLDPLYNQVLLFPES	RIMS4	176	Q9H426
LDPVYLPAALELLDA	TMEM132A	41	Q24JP5
ELYIPSVDLLTAQDL	NBR1	546	Q14596
PLYTAEPVTLEDLQL	OGA	546	O60502
IVLLPLPTAYELDST	NRXN3	506	Q9HDB5
ELPDSVLLEIFSYLP	FBXL12	6	Q9NXK8
RITDPEYLPSEQDVL	GNAT2	161	P19087
EREPAPLLSAQYETL	NCOR1	2421	O75376
PELIELLLITTNPYD	MYH3	296	P11055
TEQLVSPEPEVYEIL	PPM1B	216	O75688
ASYRLLPDITLLEPV	POLR1C	231	O15160
SLYVELLSETPANPL	SEZ6L2	436	Q6UXD5
LTYSNETEPVRALLP	FAM13C	476	Q8NE31
PYVLNDLEAEASLPE	NOP16	91	Q9Y3C1
YQSLTELNDSPVPLE	STXBP5L	726	Q9Y2K9
PELPAEQSLTEYSDL	SLFNL1	26	Q499Z3
ALLDYLDAEELPPAL	SUPT20HL2	111	P0C7V6
NSEEDQVLYLPLLPS	CFAP210	26	Q0VFZ6
NEVALLTSLPPNYEI	CLLU1-AS1	46	Q5K130
PLELSQPLSGLVDDY	C11orf94	46	C9JXX5
YDIIPETLLELGEIP	SKP2	346	Q13309
TQESILLPRISPEEY	SPG11	861	Q96JI7
LPEELLSFDYSVPEI	PRR22	331	Q8IZ63
LLPVLTDPALNDLYV	THBS4	46	P35443
EGPLRPVLEYIDLVS	ZNF451	36	Q9Y4E5
EDLLNELPYPIDIAS	USPL1	936	Q5W0Q7
PDSPQGIYDTLLELR	VPS11	616	Q9H270
TVDLPVYVLQEVLPS	ZXDC	821	Q2QGD7
STPLLPEVEAYLQLL	PSMD3	156	O43242
NTNILPTEEEGYPLL	MPDZ	506	O75970
VASALEYLLSLDLPP	THAP9	486	Q9H5L6
AILLSPVETPYANVD	SYBU	551	Q9NX95
LDYQDPLDPTRSVIV	PATJ	701	Q8NI35
LITADLEVPSPTRYQ	STPG3	96	Q8N7X2
AVEALPLVEAIEIYP	ZNF574	871	Q6ZN55
PLVEAIEIYPLAEAE	ZNF574	876	Q6ZN55
LLEYLDAEELPPILV	SUPT20H	111	Q8NEM7
SLLSDDVEPYPEVDI	TBC1D9	756	Q6ZT07
KTSEDPLPLLEVYTV	ZNF292	66	O60281
LQESVPDPELIDLIY	UBL7	51	Q96S82
DIPFLSYLPTEVQLI	YJEFN3	171	A6XGL0
SLVSDEDYLNPPVID	VPS13C	1276	Q709C8
PLIVNTVALPDELSY	VPS13C	2636	Q709C8
ELENAPALAVLPIYS	DHX38	766	Q92620
VLERTYPALETLTEP	PSME4	436	Q14997
PSVTDLLNYFLAPEI	USP38	716	Q8NB14
PAPIYILDEVDAALD	SMC2	1106	O95347
PPLTQDLLQEEDFYI	VILL	271	O15195
LLPELTNPDELLSYL	ZMIZ2	886	Q8NF64
EYESLLLQVSEPVNP	nan	501	Q3C1V9
VSIVLEYLQEEPPIP	TRPM1	261	Q7Z4N2
TVEALLTPREIPALY	VWA5B2	536	Q8N398
SSLLYLPPEQQTDDL	PSMD5	366	Q16401
PSLRLYDLELDPTAL	TMC6	126	Q7Z403
EESLLVLPFSYVPDI	WDR3	821	Q9UNX4
PEDDVYLPSEILLQE	TGM7	146	Q96PF1
LVPRSPQELYELTSL	TRIP12	716	Q14669
LDPLDLLPYSETRLD	ZC3H7B	346	Q9UGR2
DPYTLAIDVLDSPQA	TH	491	P07101
TPAELYNAILVDTPL	ATP6V0D1	146	P61421
SILDLPETNILSYFP	DUSP19	116	Q8WTR2
YGPSTEPLLLLEEIE	N4BP1	371	O75113