Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	thymidylate kinase activity	DTYMK CMPK2	4.60e-05	2	136	2	GO:0004798
GeneOntologyMolecularFunction	alpha-aminoacyl-tRNA binding	GTPBP1 GTPBP2	1.38e-04	3	136	2	GO:1904678
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DYNC2H1 DNAH2	2.34e-04	18	136	3	GO:0008569
GeneOntologyMolecularFunction	phosphatidylethanolamine transfer activity	MTTP PLTP	2.74e-04	4	136	2	GO:1904121
GeneOntologyMolecularFunction	glycolipid transfer activity	CLN3 PLTP	2.74e-04	4	136	2	GO:0017089
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA7 MTTP PLTP	3.24e-04	20	136	3	GO:0008525
GeneOntologyMolecularFunction	cholesterol transfer activity	APOB MTTP PLTP	5.63e-04	24	136	3	GO:0120020
GeneOntologyMolecularFunction	lipid transfer activity	APOB CLN3 MTTP PLTP	6.15e-04	57	136	4	GO:0120013
GeneOntologyMolecularFunction	sterol transfer activity	APOB MTTP PLTP	6.37e-04	25	136	3	GO:0120015
GeneOntologyMolecularFunction	phosphatidylcholine transfer activity	MTTP PLTP	6.78e-04	6	136	2	GO:0120019
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DYNC2H1 DNAH2	8.94e-04	28	136	3	GO:0051959
GeneOntologyBiologicalProcess	dTDP biosynthetic process	DTYMK CMPK2	4.25e-05	2	135	2	GO:0006233
GeneOntologyBiologicalProcess	dTDP metabolic process	DTYMK CMPK2	4.25e-05	2	135	2	GO:0046072
GeneOntologyBiologicalProcess	cilium movement	CFAP47 DNHD1 DYNC2H1 CAMSAP3 DNAH2 APOB TTLL8 FSIP2 PLTP	5.66e-05	261	135	9	GO:0003341
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	CFAP47 DNHD1 DYNC2H1 DNAH2 APOB TTLL8 FSIP2 PLTP	7.41e-05	210	135	8	GO:0060294
GeneOntologyBiologicalProcess	cilium-dependent cell motility	CFAP47 DNHD1 DYNC2H1 DNAH2 APOB TTLL8 FSIP2 PLTP	8.73e-05	215	135	8	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	CFAP47 DNHD1 DYNC2H1 DNAH2 APOB TTLL8 FSIP2 PLTP	8.73e-05	215	135	8	GO:0001539
GeneOntologyBiologicalProcess	microtubule-based movement	CFAP47 DNHD1 DYNC2H1 CAMSAP3 DNAH2 APOB TTLL8 FSIP2 BORCS5 CLN3 AP3D1 PLTP	9.85e-05	493	135	12	GO:0007018
GeneOntologyBiologicalProcess	dUDP biosynthetic process	DTYMK CMPK2	1.27e-04	3	135	2	GO:0006227
GeneOntologyBiologicalProcess	dUDP metabolic process	DTYMK CMPK2	1.27e-04	3	135	2	GO:0046077
GeneOntologyBiologicalProcess	pyrimidine deoxyribonucleoside diphosphate metabolic process	DTYMK CMPK2	1.27e-04	3	135	2	GO:0009196
GeneOntologyBiologicalProcess	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	DTYMK CMPK2	1.27e-04	3	135	2	GO:0009197
GeneOntologyBiologicalProcess	ceramide transport	CLN3 MTTP PLTP	2.08e-04	18	135	3	GO:0035627
GeneOntologyBiologicalProcess	dTTP biosynthetic process	DTYMK CMPK2	2.53e-04	4	135	2	GO:0006235
GeneOntologyBiologicalProcess	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	DTYMK CMPK2	2.53e-04	4	135	2	GO:0009212
GeneOntologyCellularComponent	motile cilium	CFAP47 DNHD1 DYNC2H1 PCDH11Y CAMSAP3 DNAH2 TTLL8 CEP164 FSIP2 MROH2B	1.20e-04	355	137	10	GO:0031514
GeneOntologyCellularComponent	9+2 motile cilium	DNHD1 DYNC2H1 PCDH11Y DNAH2 TTLL8 CEP164 FSIP2 MROH2B	1.78e-04	238	137	8	GO:0097729
GeneOntologyCellularComponent	lateral element	SYCP2L BRCA2 STAG3	2.47e-04	19	137	3	GO:0000800
GeneOntologyCellularComponent	PR-DUB complex	ASXL1 ASXL3	2.54e-04	4	137	2	GO:0035517
Domain	Vitellinogen_superhlx	CAND1 APOB MTTP	3.45e-07	3	132	3	IPR011030
Domain	ARM-like	CAND1 CUL9 HUWE1 PACRGL NF1 MROH1 AP2B1 MROH2B AP4B1 STAG3 AP3D1 ARMC8	4.89e-07	270	132	12	IPR011989
Domain	-	CAND1 CUL9 PACRGL NF1 MROH1 AP2B1 MROH2B AP4B1 STAG3 AP3D1 ARMC8	5.13e-07	222	132	11	1.25.10.10
Domain	ARM-type_fold	CAND1 CUL9 APOB HUWE1 PACRGL NF1 MROH1 AP2B1 MROH2B AP4B1 STAG3 AP3D1 ARMC8	8.54e-07	339	132	13	IPR016024
Domain	EamA	SLC35G6 SLC35G4 SLC35G3 SLC35G5	2.26e-06	14	132	4	PF00892
Domain	EamA_dom	SLC35G6 SLC35G4 SLC35G3 SLC35G5	2.26e-06	14	132	4	IPR000620
Domain	Thymidylate_kinase	DTYMK CMPK2	4.96e-05	2	132	2	IPR018094
Domain	Vitellinogen_b-sht_N	APOB MTTP	4.96e-05	2	132	2	IPR015816
Domain	Lipid_transp_b-sht_shell	APOB MTTP	4.96e-05	2	132	2	IPR015819
Domain	-	APOB MTTP	4.96e-05	2	132	2	2.30.230.10
Domain	VITELLOGENIN	APOB MTTP	4.96e-05	2	132	2	PS51211
Domain	THYMIDYLATE_KINASE	DTYMK CMPK2	4.96e-05	2	132	2	PS01331
Domain	LPD_N	APOB MTTP	4.96e-05	2	132	2	SM00638
Domain	Lipid_transpt_N	APOB MTTP	4.96e-05	2	132	2	IPR001747
Domain	-	APOB MTTP	4.96e-05	2	132	2	1.25.10.20
Domain	Vitellogenin_N	APOB MTTP	4.96e-05	2	132	2	PF01347
Domain	LBP_BPI_CETP	BPIFB3 BPIFA1 PLTP	9.37e-05	13	132	3	PF01273
Domain	BPI/LBP/Plunc	BPIFB3 BPIFA1 PLTP	9.37e-05	13	132	3	IPR032942
Domain	Bactericidal_perm-incr_a/b_dom	BPIFB3 BPIFA1 PLTP	9.37e-05	13	132	3	IPR017943
Domain	Lipid-bd_serum_glycop_N	BPIFB3 BPIFA1 PLTP	9.37e-05	13	132	3	IPR017942
Domain	Dynein_HC_stalk	DNHD1 DYNC2H1 DNAH2	1.19e-04	14	132	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC2H1 DNAH2	1.19e-04	14	132	3	IPR013602
Domain	DHC_N2	DNHD1 DYNC2H1 DNAH2	1.19e-04	14	132	3	PF08393
Domain	MT	DNHD1 DYNC2H1 DNAH2	1.19e-04	14	132	3	PF12777
Domain	HEAT_REPEAT	CAND1 MROH1 MROH2B AP3D1 ARMC8	1.37e-04	70	132	5	PS50077
Domain	DHC_fam	DNHD1 DYNC2H1 DNAH2	1.48e-04	15	132	3	IPR026983
Domain	Clathrin/coatomer_adapt-like_N	AP2B1 AP4B1 AP3D1	1.48e-04	15	132	3	IPR002553
Domain	Dynein_heavy	DNHD1 DYNC2H1 DNAH2	1.48e-04	15	132	3	PF03028
Domain	Adaptin_N	AP2B1 AP4B1 AP3D1	1.48e-04	15	132	3	PF01602
Domain	Dynein_heavy_dom	DNHD1 DYNC2H1 DNAH2	1.48e-04	15	132	3	IPR004273
Domain	HARE-HTH	ASXL1 ASXL3	1.48e-04	3	132	2	PF05066
Domain	ASXH	ASXL1 ASXL3	1.48e-04	3	132	2	PF13919
Domain	PHD_3	ASXL1 ASXL3	1.48e-04	3	132	2	PF13922
Domain	ASX-like_PHD	ASXL1 ASXL3	1.48e-04	3	132	2	IPR026905
Domain	ASXH	ASXL1 ASXL3	1.48e-04	3	132	2	IPR028020
Domain	AP_complex_bsu_1_2_4	AP2B1 AP4B1	1.48e-04	3	132	2	IPR016342
Domain	ASX/ASX-like	ASXL1 ASXL3	1.48e-04	3	132	2	IPR024811
Domain	HB1/Asxl_HTH	ASXL1 ASXL3	1.48e-04	3	132	2	IPR007759
Domain	B2-adapt-app_C	AP2B1 AP4B1	1.48e-04	3	132	2	PF09066
Domain	B2-adapt-app_C	AP2B1 AP4B1	2.95e-04	4	132	2	SM01020
Domain	B-adaptin_app_sub_C	AP2B1 AP4B1	2.95e-04	4	132	2	IPR015151
Domain	AP_beta	AP2B1 AP4B1	4.89e-04	5	132	2	IPR026739
Domain	Beta2_adaptin/TBP_C_dom	AP2B1 AP4B1	7.30e-04	6	132	2	IPR012295
Domain	-	AP2B1 AP4B1	7.30e-04	6	132	2	3.30.310.10
Domain	-	DNHD1 NWD1 DYNC2H1 DTYMK NDST2 DNAH2 CMPK2 GTPBP1 ABCA7 MFN1 DHX9 GTPBP2 NLRC5 TAP1	8.18e-04	746	132	14	3.40.50.300
Domain	DHC_N1	DYNC2H1 DNAH2	1.35e-03	8	132	2	PF08385
Domain	Transl_elong_EFTu/EF1A_C	GTPBP1 GTPBP2	1.35e-03	8	132	2	IPR004160
Domain	Coatomer/calthrin_app_sub_C	AP2B1 AP4B1	1.35e-03	8	132	2	IPR009028
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2	1.35e-03	8	132	2	IPR013594
Domain	GTP_EFTU_D3	GTPBP1 GTPBP2	1.35e-03	8	132	2	PF03143
Domain	BPI1	BPIFB3 PLTP	1.73e-03	9	132	2	SM00328
Domain	BPI2	BPIFB3 PLTP	1.73e-03	9	132	2	SM00329
Domain	LBP_BPI_CETP	BPIFB3 PLTP	1.73e-03	9	132	2	PS00400
Domain	LBP_BPI_CETP_C	BPIFB3 PLTP	2.15e-03	10	132	2	PF02886
Domain	Transl_elong_EF1A/Init_IF2_C	GTPBP1 GTPBP2	2.15e-03	10	132	2	IPR009001
Domain	Laminin_G_1	SHBG CSPG4	2.62e-03	11	132	2	PF00054
Domain	P-loop_NTPase	DNHD1 NWD1 DYNC2H1 DTYMK NDST2 DNAH2 CMPK2 GTPBP1 ABCA7 MFN1 DHX9 GTPBP2 NLRC5 TAP1	2.71e-03	848	132	14	IPR027417
Domain	Lipid-bd_serum_glycop_C	BPIFB3 PLTP	3.12e-03	12	132	2	IPR001124
Domain	RasGAP	SYNGAP1 NF1	4.27e-03	14	132	2	SM00323
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH2	4.27e-03	14	132	2	IPR024317
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH2	4.27e-03	14	132	2	IPR011704
Domain	AAA_8	DYNC2H1 DNAH2	4.27e-03	14	132	2	PF12780
Domain	RasGAP_CS	SYNGAP1 NF1	4.27e-03	14	132	2	IPR023152
Domain	AAA_5	DYNC2H1 DNAH2	4.27e-03	14	132	2	PF07728
Domain	RasGAP	SYNGAP1 NF1	4.90e-03	15	132	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	SYNGAP1 NF1	4.90e-03	15	132	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	SYNGAP1 NF1	4.90e-03	15	132	2	PS50018
Domain	EFTu-like_2	GTPBP1 GTPBP2	7.04e-03	18	132	2	IPR004161
Domain	RasGAP_dom	SYNGAP1 NF1	7.04e-03	18	132	2	IPR001936
Domain	GTP_EFTU_D2	GTPBP1 GTPBP2	7.04e-03	18	132	2	PF03144
Domain	G_TR_2	GTPBP1 GTPBP2	7.04e-03	18	132	2	PS51722
Pubmed	RT-PCR of fatty acid elongases.	SLC35G6 SLC35G4 SLC35G3 SLC35G5	2.30e-10	4	137	4	9056918
Pubmed	Emergence of primate genes by retrotransposon-mediated sequence transduction.	SLC35G6 SLC35G4 SLC35G3 SLC35G5	2.30e-10	4	137	4	17101974
Pubmed	Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.	APOB ABCA7 TRPM3 MTTP PLTP	3.72e-06	59	137	5	20855565
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 CUL9 HUWE1 ABCA7 MST1R HAUS4 MROH1 MEGF6 FANCI CLN3 ZNF408 PPP1R15B CSPG4 NLRC5 ARRDC2 AP3D1	7.84e-06	1105	137	16	35748872
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	GPI CAND1 EMC1 DHX9 PPP1CB NUP205 AP2B1 TAP1	1.19e-05	268	137	8	33024031
Pubmed	Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13.	STAT6 SCGB3A1	1.54e-05	2	137	2	16237061
Pubmed	Human placenta secretes apolipoprotein B-100-containing lipoproteins.	APOB MTTP	1.54e-05	2	137	2	15504742
Pubmed	Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.	ASXL1 NF1	1.54e-05	2	137	2	30226831
Pubmed	Microsomal triglyceride transfer protein gene expression and ApoB secretion are inhibited by bitter melon in HepG2 cells.	APOB MTTP	1.54e-05	2	137	2	15795421
Pubmed	Cloning, expression analysis, and chromosomal mapping of GTPBP2, a novel member of the G protein family.	GTPBP1 GTPBP2	1.54e-05	2	137	2	11054535
Pubmed	A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion.	APOB MTTP	1.54e-05	2	137	2	10713055
Pubmed	Molecular characterization of the murine thymidylate kinase gene.	DTYMK CMPK2	1.54e-05	2	137	2	8845311
Pubmed	Bi-allelic genetic variants in the translational GTPases GTPBP1 and GTPBP2 cause a distinct identical neurodevelopmental syndrome.	GTPBP1 GTPBP2	1.54e-05	2	137	2	38118446
Pubmed	Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia.	APOB MTTP	1.54e-05	2	137	2	24842304
Pubmed	Microsomal triglyceride transfer protein binding and lipid transfer activities are independent of each other, but both are required for secretion of apolipoprotein B lipoproteins from liver cells.	APOB MTTP	1.54e-05	2	137	2	11358959
Pubmed	Identification of Novel Phospholipid Transfer Protein Inhibitors by High-Throughput Screening.	APOB PLTP	1.54e-05	2	137	2	31017809
Pubmed	Crystallization and preliminary crystallographic studies of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.	STAT6 NCOA1	1.54e-05	2	137	2	14993689
Pubmed	Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2.	GTPBP1 GTPBP2	1.54e-05	2	137	2	30108131
Pubmed	Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects.	APOB MTTP	1.54e-05	2	137	2	27487388
Pubmed	Identification of patients with abetalipoproteinemia and homozygous familial hypobetalipoproteinemia in Tunisia.	APOB MTTP	1.54e-05	2	137	2	19056372
Pubmed	Relationship between Amphipathic β Structures in the β1 Domain of Apolipoprotein B and the Properties of the Secreted Lipoprotein Particles in McA-RH7777 Cells.	APOB MTTP	1.54e-05	2	137	2	28702990
Pubmed	A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase.	APOB MTTP	1.54e-05	2	137	2	9915855
Pubmed	Novel mutations in abetalipoproteinaemia and homozygous familial hypobetalipoproteinaemia.	APOB MTTP	1.54e-05	2	137	2	18027103
Pubmed	Hypobetalipoproteinemia with an apparently recessive inheritance due to a "de novo" mutation of apolipoprotein B.	APOB MTTP	1.54e-05	2	137	2	14732481
Pubmed	Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.	APOB MTTP	1.54e-05	2	137	2	17690102
Pubmed	Loss of the tumor suppressor BAP1 causes myeloid transformation.	ASXL1 KDM1B ARMC8	1.66e-05	13	137	3	22878500
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CAND1 CAMSAP3 PPP1CB SYNGAP1 NF1 AP2B1 PHF3 PLCL1	1.67e-05	281	137	8	28706196
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GPI RNF130 DYNC2H1 DTYMK SMCHD1 APOB HUWE1 CEMIP2 STAT6 NUP205 NF1 MROH1 FANCI ENTPD6 ITM2B	2.03e-05	1061	137	15	33845483
Pubmed	Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.	BPIFB3 BPIFA1 PLTP	2.63e-05	15	137	3	21787333
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	SFTPB DYNC2H1 DNAH2 NF1	3.60e-05	47	137	4	8812413
Pubmed	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	GPI CAND1 EVPL SIRPB1 AP2B1	4.25e-05	97	137	5	22360420
Pubmed	C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.	APOB NF1	4.61e-05	3	137	2	11727199
Pubmed	Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria.	MDH2 MMUT	4.61e-05	3	137	2	31648943
Pubmed	Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.	APOB MTTP	4.61e-05	3	137	2	19026012
Pubmed	GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis.	GTPBP1 GTPBP2	4.61e-05	3	137	2	33186095
Pubmed	Pregnane X receptor polymorphism affects CYP3A4 induction via a ligand-dependent interaction with steroid receptor coactivator-1.	CYP3A4 NCOA1	4.61e-05	3	137	2	17429319
Pubmed	Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition.	APOB MTTP	4.61e-05	3	137	2	18502767
Pubmed	Neurofibromatosis with male breast cancer--risk factor or co-incidence? Report of two rare cases.	NF1 BRCA2	4.61e-05	3	137	2	25267367
Pubmed	Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.	STAT6 NCOA1	4.61e-05	3	137	2	11574547
Pubmed	Diabetes adversely affects macrophages during atherosclerotic plaque regression in mice.	APOB MTTP	4.61e-05	3	137	2	21562077
Pubmed	Mechanism of RAD51-dependent DNA interstrand cross-link repair.	BRCA2 FANCI	4.61e-05	3	137	2	21719678
Pubmed	Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.	APOB MTTP	4.61e-05	3	137	2	17647275
Pubmed	Mouse and human GTPBP2, newly identified members of the GP-1 family of GTPase.	GTPBP1 GTPBP2	4.61e-05	3	137	2	10833435
Pubmed	Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal β-Barrel in Microsomal Triglyceride Transfer Protein Function.	APOB MTTP	4.61e-05	3	137	2	26224785
Pubmed	Lowering plasma cholesterol levels halts progression of aortic valve disease in mice.	APOB MTTP	4.61e-05	3	137	2	19433756
Pubmed	Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.	ASXL1 ASXL3	4.61e-05	3	137	2	16412590
Pubmed	Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development.	APOB MTTP	4.61e-05	3	137	2	10553000
Pubmed	Identification of genes differentially induced by hypoxia in pancreatic cancer cells.	GPI BHLHE40	4.61e-05	3	137	2	11688991
Pubmed	An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.	STAT6 NCOA1	4.61e-05	3	137	2	12138096
Pubmed	Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.	APOB MTTP	4.61e-05	3	137	2	24586211
Pubmed	Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.	ASXL1 ASXL3	4.61e-05	3	137	2	25835095
Pubmed	Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.	APOB MTTP	4.61e-05	3	137	2	38211723
Pubmed	Complex genetic architecture in severe hypobetalipoproteinemia.	APOB MTTP	4.61e-05	3	137	2	29540175
Pubmed	Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.	STAT6 NCOA1	4.61e-05	3	137	2	14757047
Pubmed	Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism.	BRCA2 FANCI	4.61e-05	3	137	2	28684355
Pubmed	ApoB100-LDL acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes.	APOB MTTP	4.61e-05	3	137	2	19020660
Pubmed	Understanding the phenotypic spectrum of ASXL-related disease: Ten cases and a review of the literature.	ASXL1 ASXL3	4.61e-05	3	137	2	33751773
Pubmed	DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes.	CYP3A4 BHLHE40	4.61e-05	3	137	2	22728071
Pubmed	Vascular function during prolonged progression and regression of atherosclerosis in mice.	APOB MTTP	4.61e-05	3	137	2	23307875
Pubmed	Microsomal triglyceride transfer protein expression during mouse development.	APOB MTTP	4.61e-05	3	137	2	10744773
Pubmed	Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion.	APOB MTTP	4.61e-05	3	137	2	12628954
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPI DNHD1 CAND1 EMC1 DYNC2H1 SMCHD1 APOB HUWE1 MDH2 GTPBP1 LAP3 DHX9 NUP205 NF1 FANCI ITM2B ARMC8	4.76e-05	1425	137	17	30948266
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	GPI CAND1 SEC24A APOB HUWE1 C2CD4C CEMIP2 DHX9 STIM1 GTPBP2 PPP1R15B AP3D1	6.19e-05	777	137	12	35844135
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	ASXL1 ASXL3 KDM1B	6.49e-05	20	137	3	29785026
Pubmed	Conservation of autosomal gene synteny groups in mouse and man.	GPI MDH2 LAP3	6.49e-05	20	137	3	662012
Pubmed	Derlin-1 promotes ubiquitylation and degradation of the epithelial Na+ channel, ENaC.	CAND1 SMCHD1 HUWE1 MDH2	6.72e-05	55	137	4	28137758
Pubmed	Molecular analysis of APOB, SAR1B, ANGPTL3, and MTTP in patients with primary hypocholesterolemia in a clinical laboratory setting: Evidence supporting polygenicity in mutation-negative patients.	APOB MTTP	9.19e-05	4	137	2	30782561
Pubmed	Association between shear stress and platelet-derived transforming growth factor-β1 release and activation in animal models of aortic valve stenosis.	APOB MTTP	9.19e-05	4	137	2	24903096
Pubmed	The influence of molecular biology on our understanding of lipoprotein metabolism and the pathobiology of atherosclerosis.	APOB MTTP	9.19e-05	4	137	2	7741021
Pubmed	Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice.	APOB MTTP	9.19e-05	4	137	2	18645210
Pubmed	Novel missense MTTP gene mutations causing abetalipoproteinemia.	APOB MTTP	9.19e-05	4	137	2	25108285
Pubmed	AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.	CLN3 AP3D1	9.19e-05	4	137	2	15598649
Pubmed	Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouse.	GPI MDH2	9.19e-05	4	137	2	5496232
Pubmed	Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain Binding.	ASXL1 ASXL3	9.19e-05	4	137	2	34536441
Pubmed	Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells.	CYP3A4 BHLHE40	9.19e-05	4	137	2	26340669
Pubmed	Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.	APOB MTTP	9.19e-05	4	137	2	18369455
Pubmed	Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.	APOB MTTP	9.19e-05	4	137	2	25474352
Pubmed	Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques.	APOB MTTP	9.19e-05	4	137	2	21339485
Pubmed	P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.	STAT6 NCOA1	9.19e-05	4	137	2	18267973
Pubmed	Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration.	APOB MTTP	9.19e-05	4	137	2	28062492
Pubmed	ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice.	APOB MTTP	9.19e-05	4	137	2	18519977
Pubmed	miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice.	APOB MTTP	9.19e-05	4	137	2	25201910
Pubmed	Genetic factors controlling structure and expression of apolipoproteins B and E in mice.	GPI APOB	9.19e-05	4	137	2	3034900
Pubmed	NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma.	NF1 CSPG4	9.19e-05	4	137	2	23318450
Pubmed	Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition.	BRCA2 FANCI	9.19e-05	4	137	2	19737859
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	RNF130 CAND1 DTYMK SMCHD1 HUWE1 GTPBP1 DHX9 NF1 FANCI RAVER1	1.09e-04	582	137	10	20467437
Pubmed	Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity.	EMC1 APOB MTTP	1.14e-04	24	137	3	25009997
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SEC24A CARMIL1 CAMSAP3 GTPBP1 CEP164 NUP205 HAUS4 BORCS5 BRCA2 WDCP AP4B1 RAVER1	1.48e-04	853	137	12	28718761
Pubmed	HIV-1 matrix protein: a mysterious regulator of the viral life cycle.	AP2B1 AP3D1	1.53e-04	5	137	2	17210199
Pubmed	ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.	SFTPB ABCA7	1.53e-04	5	137	2	17142808
Pubmed	Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.	BRCA2 FANCI	1.53e-04	5	137	2	15199141
Pubmed	Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression.	APOB MTTP	1.53e-04	5	137	2	25765938
Pubmed	Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics.	CYP3A4 NCOA1	1.53e-04	5	137	2	12072427
Pubmed	Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse placentas.	APOB MTTP	1.53e-04	5	137	2	37315736
Pubmed	Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation.	APOB MTTP	1.53e-04	5	137	2	12072432
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 CAMSAP3 DNAH2 ARHGAP9 EVPL HUWE1 DHX9 NUP205 MEGF6 TRPM3 ZNF408	1.68e-04	736	137	11	29676528
Pubmed	Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.	ASXL1 ACRBP PCDH11Y NF1 AP3D1 CCDC136 MMUT	1.70e-04	293	137	7	31741433
Pubmed	Genetic link between renal birth defects and congenital heart disease.	FRAS1 DYNC2H1 AP2B1	1.82e-04	28	137	3	27002738
Pubmed	Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.	APOB SLC35G5 PLTP	2.03e-04	29	137	3	20972250
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	FRAS1 SMCHD1 CAMSAP3 APOB MFN1 DHX9 ASXL3 IGSF1 CCDC136	2.08e-04	513	137	9	25798074
GeneFamily	BPI fold containing	BPIFB3 BPIFA1 PLTP	4.48e-05	16	80	3	456
GeneFamily	Solute carriers	SLC39A4 SLC35G6 SLC35G4 SLC41A3 SLC35G3 SLC35G5 SLC16A7 SLC4A9	3.55e-04	395	80	8	752
GeneFamily	Maestro heat like repeat containing	MROH1 MROH2B	1.04e-03	11	80	2	636
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM8 ZNF408	2.52e-03	17	80	2	1197
Coexpression	DESCARTES_ORGANOGENESIS_HEPATOCYTES	CYP3A4 SEC24A SHBG SLC39A4 APOB BHLHE40 FAAH AGXT2 RASSF6 WDCP QPRT MTTP IGSF1	4.93e-06	535	137	13	MM3635
Coexpression	NAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP	CAND1 SEC24A SMCHD1 NDST2 HUWE1 CEMIP2 NF1 GVINP1 BRCA2 AP2B1 MMUT ARMC8	7.85e-06	475	137	12	M40979
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	DNAH2 ARHGAP9 STAT6 FSIP2 PRELP QPRT CSPG4 ARRDC2	2.03e-07	200	137	8	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	DNAH2 ARHGAP9 STAT6 FSIP2 PRELP QPRT CSPG4 ARRDC2	2.03e-07	200	137	8	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SMCHD1 CMPK2 GTPBP1 LAP3 TAP1 DOP1A SAMD4A	2.47e-06	195	137	7	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Fos_(Deep_layer_pyramidal_cells--layer_5_(IEG))\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	DNHD1 MMS22L DNAH2 RASSF6 IGSF1	4.03e-06	77	137	5	4879a1a72b950dadb78bc0312be75f1a32b935d5
ToppCell	PCW_05-06-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CFAP47 ADGRG3 TMEM79 APOB RASSF6 MTTP	4.79e-06	140	137	6	8abbd5dc799943b49cd0045d0da405c3f3d0db6b
ToppCell	PCW_05-06-Epithelial-Epithelial_ciliated\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CFAP47 ADGRG3 TMEM79 APOB RASSF6 MTTP	4.79e-06	140	137	6	e4689232c473d239b07a7fbcaaa3414fbd9badea
ToppCell	10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Lung / Manually curated celltypes from each tissue	DNHD1 MMS22L ADGRG3 PRDM8 TIGD2 FANCI	1.31e-05	167	137	6	dcbcc658082910838c8082d71a64917055086cc4
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFTPB CAMSAP3 ISM2 EGFL6 FANCI ASXL3	1.45e-05	170	137	6	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACRBP TMEM79 BPIFA1 SCGB3A1 BRCA2 RASSF6	2.49e-05	187	137	6	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACRBP TMEM79 BPIFA1 SCGB3A1 BRCA2 RASSF6	2.49e-05	187	137	6	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACRBP TMEM79 BPIFA1 SCGB3A1 BRCA2 RASSF6	2.49e-05	187	137	6	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	control-Myeloid-Neutrophils_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADGRG3 SMCHD1 PPCDC ARHGAP9 SIRPB1 ITM2B	3.24e-05	196	137	6	9c8623232c47af5de9f360fd5c5113362e37c6c9
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	SMCHD1 CMPK2 LAP3 NLRC5 TAP1 DOP1A	3.24e-05	196	137	6	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SMCHD1 CMPK2 BHLHE40 LAP3 CEMIP2 PHF3	3.33e-05	197	137	6	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMCHD1 CMPK2 BHLHE40 LAP3 CEMIP2 PHF3	3.43e-05	198	137	6	44417089b62056269cac38d3134ff209c05b7007
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	SMCHD1 CMPK2 LAP3 NLRC5 TAP1 DOP1A	3.43e-05	198	137	6	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	Biopsy_Control_(H.)-Epithelial-SCGB3A2+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FRAS1 SFTPB EVPL SCGB3A1 PLCL1 IGSF1	3.43e-05	198	137	6	1fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMCHD1 CMPK2 BHLHE40 LAP3 CEMIP2 PHF3	3.43e-05	198	137	6	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTPB BHLHE40 SCGB3A1 PRDM8 TRPM3 PLCL1	3.43e-05	198	137	6	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	control-CD163+_Monocytes_(Sample_ID1_d7)\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF130 CMPK2 SIRPB1 LAP3 GTPBP2 SAMD4A	3.53e-05	199	137	6	933201d32eda12a89660bdbae9114a95cc428a38
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ARHGEF25 EGFL6 PPP1CB PRELP CSPG4	3.53e-05	199	137	6	9a08c25bb4851ad4ac9db8916422280f71378c2c
ToppCell	droplet-Trachea\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BPIFA1 BHLHE40 SCGB3A1 PRELP CSPG4 SAMD4A	3.53e-05	199	137	6	1c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	GPI MMS22L ADGRG3 BRCA2 CENPM FANCI	3.53e-05	199	137	6	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	GPI MMS22L ADGRG3 BRCA2 CENPM FANCI	3.53e-05	199	137	6	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	droplet-Trachea\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BPIFA1 BHLHE40 SCGB3A1 PRELP CSPG4 SAMD4A	3.53e-05	199	137	6	b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ARHGEF25 EGFL6 PPP1CB PRELP CSPG4	3.53e-05	199	137	6	2ed10c5e15c9d5ed0a8bea580842348d5698a07b
ToppCell	TCGA-Lung\|World / Sample_Type by Project: Shred V9	SFTPB DNAH2 BPIFA1 EGFL6 SCGB3A1	1.01e-04	150	137	5	8c133206786e8f22bb70f2a7de9c0cb7f9ea9313
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPB SCGB3A1 ASXL3 MTTP SIGLEC11	1.14e-04	154	137	5	ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 EGFL6 PRELP FANCI STAG3	1.14e-04	154	137	5	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	Adult-Epithelial-basal_cell-D122\|Adult / Lineage, Cell type, age group and donor	FRAS1 NWD1 RASSF6 ASXL3 MTTP	1.14e-04	154	137	5	38d346402417960044ae999e61f0092b46f2b591
ToppCell	10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-\|Lung / Manually curated celltypes from each tissue	ADGRG3 ADAMTS1 ARHGAP9 CEMIP2 PRELP	1.33e-04	159	137	5	595643e9433265308e5aab7f906229025701cf6a
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ISM2 PRELP CLN3 CSPG4 AP4B1	1.41e-04	161	137	5	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNHD1 SFTPB ISM2 EGFL6 RASSF6	1.45e-04	162	137	5	8e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNHD1 SFTPB ISM2 EGFL6 RASSF6	1.45e-04	162	137	5	e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCell	Ionocyte\|World / shred by cell class for turbinate	SFTPB CYP3A4 RASSF6 PLCL1 SLC4A9	1.58e-04	165	137	5	0cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFAP47 ADGRG3 ACRBP STAG3	1.64e-04	89	137	4	eda156a61e7d14087cfdae5e733d6862834fb0e5
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 PCDH11Y APOB EGFL6 PRELP	1.72e-04	168	137	5	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 NWD1 BHLHE40 SCGB3A1 RASSF6	1.72e-04	168	137	5	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 PCDH11Y APOB EGFL6 PRELP	1.72e-04	168	137	5	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 NWD1 BHLHE40 SCGB3A1 RASSF6	1.76e-04	169	137	5	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	RNF130 NUP205 FANCI PLTP DOP1A	1.81e-04	170	137	5	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DTYMK FAAH BRCA2 CENPM FANCI	1.92e-04	172	137	5	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	RNF130 NUP205 FANCI PLTP DOP1A	1.97e-04	173	137	5	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 DNAH2 CEMIP2 ITM2B PLTP	2.08e-04	175	137	5	1c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DTYMK TIGD2 CENPM FANCI PLTP	2.08e-04	175	137	5	86dfce849b2ec023a72f7e887fa681b117155e51
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 CARMIL1 PXK STIM1 SLC4A9	2.13e-04	176	137	5	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	MMS22L HUWE1 MFN1 CEMIP2 PPP1R15B	2.19e-04	177	137	5	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 CMPK2 SCGB3A1 CSPG4 CCDC136	2.25e-04	178	137	5	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	FRAS1 SFTPB CAMSAP3 SCGB3A1 PLCL1	2.25e-04	178	137	5	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 SHBG CEMIP2 MEGF6 PLTP	2.36e-04	180	137	5	178648429686e6d4e6f3aafc350130e819788ecf
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 SHBG CEMIP2 MEGF6 PLTP	2.36e-04	180	137	5	fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 SHBG CEMIP2 MEGF6 PLTP	2.36e-04	180	137	5	c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 FBXO17 AGXT2 TRPM3 RASSF6	2.55e-04	183	137	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEMIP2 MEGF6 FANCI ZFHX2 CCDC136	2.55e-04	183	137	5	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	2.62e-04	184	137	5	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SFTPB EVPL BPIFA1 BHLHE40 SCGB3A1	2.62e-04	184	137	5	fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCell	wk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CMPK2 ABCA7 BRCA2 FANCI FBXO7	2.62e-04	184	137	5	238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 BPIFA1 PPP1CB SCGB3A1 CENPM	2.62e-04	184	137	5	2df903924df9cb71039159416bcbe6a6614e21fe
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	2.62e-04	184	137	5	603faafb7b289a3c0242c84fc800c050c8a092ea
ToppCell	mild-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADGRG3 SMCHD1 PPCDC NCOA1 ITM2B	2.62e-04	184	137	5	1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	2.62e-04	184	137	5	c350504bfe0ec31cd2fc2199de9b5fff151a8c5e
ToppCell	Club\|World / Class top	SFTPB SLC39A4 BPIFA1 SCGB3A1 SAMD4A	2.68e-04	185	137	5	c3caf789e622ed515d143dc594158d52fdcffaef
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB CAMSAP3 EGFL6 RASSF6 SLC4A9	2.75e-04	186	137	5	3c4994a1a7db06a61da8170e45e06aaef7896592
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MFN1 SCGB3A1 PRELP ARRDC2 SLC16A7	2.75e-04	186	137	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	facs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB CAMSAP3 EGFL6 RASSF6 SLC4A9	2.75e-04	186	137	5	a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MFN1 SCGB3A1 PRELP ARRDC2 SLC16A7	2.75e-04	186	137	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SFTPB SCGB3A1 PRDM8 PLCL1	2.82e-04	187	137	5	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	Club-club-14\|World / Class top	SFTPB SLC39A4 BPIFA1 FAAH SAMD4A	2.82e-04	187	137	5	4584de577d3736c89187e522497498e58d381c46
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	ASXL1 CARMIL1 PXK PLCL1 SLC4A9	2.82e-04	187	137	5	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	IPF-Stromal-SMC\|World / Disease state, Lineage and Cell class	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	2.89e-04	188	137	5	b66264e8f8d536ed2beec31e6746c687718f239b
ToppCell	wk_15-18-Hematologic-Myeloid-Basophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADGRG3 WIPI1 ABCA7 PXK MTTP	2.89e-04	188	137	5	3638d85452de15a060146628fbbad9d2a36feb13
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	ADAMTS1 ARHGEF25 EGFL6 PRELP MTTP	2.89e-04	188	137	5	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	IPF-Stromal-SMC\|IPF / Disease state, Lineage and Cell class	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	2.89e-04	188	137	5	e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMS22L DTYMK BRCA2 CENPM FANCI	2.96e-04	189	137	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 SFTPB SCGB3A1 PRDM8 PLCL1	3.03e-04	190	137	5	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ARHGEF25 EGFL6 CSPG4 PLCL1	3.03e-04	190	137	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	CMPK2 LAP3 GTPBP2 NLRC5 TAP1	3.11e-04	191	137	5	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MMS22L SMCHD1 HUWE1 CEMIP2 PPP1R15B	3.11e-04	191	137	5	9454f642c3621370fa23640b631301346b300950
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	DTYMK BRCA2 CENPM FANCI LLCFC1	3.11e-04	191	137	5	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	FRAS1 EGFL6 PRELP CSPG4 PLTP	3.11e-04	191	137	5	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ARHGEF25 EGFL6 PRELP PLCL1	3.11e-04	191	137	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	FRAS1 EGFL6 PRELP CSPG4 PLTP	3.11e-04	191	137	5	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTS1 BHLHE40 CEMIP2 MEGF6 ITM2B	3.11e-04	191	137	5	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ARHGEF25 EGFL6 PRELP PLCL1	3.18e-04	192	137	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	Pericytes\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	3.18e-04	192	137	5	057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ARHGEF25 EGFL6 QPRT PLTP	3.18e-04	192	137	5	859a32c9e4ed6961897b2ccaecde73a599471df9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 ARHGEF25 EGFL6 QPRT PLTP	3.18e-04	192	137	5	89e1da82fa2069dac7adb9cba3e8b6c0179e0dc5
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRERF1 PRDM8 TRPM3 RASSF6 CCDC136	3.18e-04	192	137	5	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L DTYMK HAUS4 BRCA2 CENPM	3.26e-04	193	137	5	40eedc1490c113403bc7c12a6bdf976f4f8bca84
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MMS22L BRCA2 CENPM FANCI IGSF1	3.26e-04	193	137	5	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ADAMTS1 ARHGEF25 EGFL6 PRELP CSPG4	3.26e-04	193	137	5	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPI MMS22L ADGRG3 BRCA2 FANCI	3.26e-04	193	137	5	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	SMCHD1 CMPK2 BHLHE40 LAP3 CEMIP2	3.26e-04	193	137	5	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	(06)_Krt4/13+-(0)_uninjured\|(06)_Krt4/13+ / shred by cell type and Timepoint	BPIFA1 SCGB3A1	3.27e-04	9	137	2	baf55476ddf9a2d1e6741a73bcc92ac9d00c2bca
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MMS22L BRCA2 CENPM FANCI IGSF1	3.34e-04	194	137	5	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	Mild/Remission-B_activate-7\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SMCHD1 CMPK2 LAP3 PPP1R15B SAMD4A	3.34e-04	194	137	5	01c97543972159a9468272da06e7e611e2c21fae
ToppCell	PBMC-Mild\|PBMC / Compartment, Disease Groups and Clusters	SMCHD1 CMPK2 BHLHE40 LAP3 TAP1	3.34e-04	194	137	5	d1366b169d14011194e61d16b6b0953349febc78
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMS22L DTYMK LAP3 CENPM PLTP	3.34e-04	194	137	5	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	mild-Myeloid-Neutrophils_1\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADGRG3 SMCHD1 PPCDC SIRPB1 ITM2B	3.34e-04	194	137	5	ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPI MMS22L ADGRG3 BRCA2 FANCI	3.34e-04	194	137	5	23318a1b55895b5166c6151f488a94a09b4627ff
Disease	immature platelet count	CARMIL1 SIRPB1 AP2B1 TRPM3 CLN3	1.30e-04	106	135	5	EFO_0803544
Disease	immature platelet measurement	CARMIL1 SIRPB1 AP2B1 TRPM3 CLN3	2.24e-04	119	135	5	EFO_0803541
Disease	total lipids in very large HDL measurement	WIPI1 APOB NLRC5 PLTP	2.42e-04	66	135	4	EFO_0022312
Disease	cholesterol in very large HDL measurement	WIPI1 APOB NLRC5 PLTP	2.88e-04	69	135	4	EFO_0022229
Disease	cholesteryl esters to total lipids in very large HDL percentage	APOB NLRC5 PLTP	5.99e-04	36	135	3	EFO_0022257
Disease	triglycerides to total lipids in large VLDL percentage	APOB NLRC5 PLTP	7.59e-04	39	135	3	EFO_0022332
Disease	familial hypercholesterolemia (is_implicated_in)	APOB MTTP	9.13e-04	10	135	2	DOID:13810 (is_implicated_in)
Disease	Fanconi anemia (is_implicated_in)	BRCA2 FANCI	9.13e-04	10	135	2	DOID:13636 (is_implicated_in)
Disease	systemic lupus erythematosus	CARMIL1 PPCDC ARHGAP9 SIRPB1 PXK SYNGAP1 STIM1 AGXT2 PLCL1 TAP1 CCDC136	1.15e-03	799	135	11	MONDO_0007915
Disease	estradiol measurement	SYCP2L CYP3A4 SHBG C2CD4C	1.66e-03	110	135	4	EFO_0004697
Disease	triglyceride measurement, intermediate density lipoprotein measurement	APOB BRCA2 MTTP PLTP	1.72e-03	111	135	4	EFO_0004530, EFO_0008595
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	WIPI1 CARMIL1 APOB MTTP NLRC5 PLTP	1.74e-03	276	135	6	EFO_0004612, EFO_0020943
Disease	Fanconi anemia	BRCA2 FANCI	1.82e-03	14	135	2	cv:C0015625
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	APOB RASSF6	1.82e-03	14	135	2	EFO_0004611, EFO_0008589
Disease	immature platelet fraction	CARMIL1 SIRPB1 TRPM3 CLN3	1.90e-03	114	135	4	EFO_0009187
Disease	Polydactyly	FRAS1 DYNC2H1 CEP164 ARMC8	2.08e-03	117	135	4	C0152427
Disease	triglycerides to total lipids in chylomicrons and extremely large VLDL percentage	APOB PLTP	2.10e-03	15	135	2	EFO_0022328
Disease	Hypertriglyceridemia	APOB PLTP	2.10e-03	15	135	2	C0020557
Disease	amenorrhea, response to antineoplastic agent	PPCDC APOB	2.10e-03	15	135	2	EFO_0010269, GO_0097327
Disease	Prostatic Neoplasms	RNF130 ACRBP CYP3A4 PCDH11Y NDST2 SHBG BRCA2 NCOA1 TAP1	2.17e-03	616	135	9	C0033578
Disease	Malignant neoplasm of prostate	RNF130 ACRBP CYP3A4 PCDH11Y NDST2 SHBG BRCA2 NCOA1 TAP1	2.17e-03	616	135	9	C0376358
Disease	triglycerides to total lipids in medium HDL percentage	APOB NLRC5 PLTP	2.17e-03	56	135	3	EFO_0022333
Disease	X-21410 measurement	CYP3A4 PTCD1	2.39e-03	16	135	2	EFO_0800813
Disease	angina pectoris	DYNC2H1 CARMIL1 APOB PRDM8	2.65e-03	125	135	4	EFO_0003913
Disease	triglycerides to total lipids in large HDL percentage	APOB NLRC5 PLTP	2.65e-03	60	135	3	EFO_0022330
Disease	cholesterol to total lipids in medium HDL percentage	APOB NLRC5 PLTP	2.65e-03	60	135	3	EFO_0022237
Disease	Inborn Errors of Metabolism	AGXT2 MMUT	2.70e-03	17	135	2	C0025521
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOB PLTP	2.70e-03	17	135	2	EFO_0022232
Disease	free cholesterol in HDL measurement	APOB NLRC5 PLTP	2.78e-03	61	135	3	EFO_0022264
Disease	phospholipids in HDL measurement	APOB NLRC5 PLTP	2.78e-03	61	135	3	EFO_0022293
Disease	free cholesterol in very large HDL measurement	WIPI1 APOB PLTP	2.91e-03	62	135	3	EFO_0022273
Disease	aspartate aminotransferase measurement	CARMIL1 DNAH2 ARHGAP9 PXK BORCS5 NF1 HMCN2 TRPM3 NLRC5 MMUT SAMD4A	3.00e-03	904	135	11	EFO_0004736
Disease	Bone marrow hypocellularity	BRCA2 FANCI	3.03e-03	18	135	2	C1855710
Disease	total lipids in HDL measurement	APOB NLRC5 PLTP	3.04e-03	63	135	3	EFO_0022307
Disease	platelet measurement	CARMIL1 SIRPB1 AP2B1 TRPM3 CLN3 SIGLEC11	3.36e-03	315	135	6	EFO_0005036
Disease	Juvenile Myelomonocytic Leukemia	ASXL1 NF1	3.38e-03	19	135	2	C0349639
Disease	ovulation	SYCP2L FANCI	3.38e-03	19	135	2	GO_0030728
Disease	response to methotrexate, neurotoxicity	STIM1 PLCL1	3.38e-03	19	135	2	EFO_0011057, GO_0031427
Disease	phospholipids in very large HDL measurement	APOB NLRC5 PLTP	3.47e-03	66	135	3	EFO_0022298
Disease	viral load	RNF130 ADAMTS1 CYP3A4 PPP1CB	3.59e-03	136	135	4	EFO_0010125
Disease	MYELODYSPLASTIC SYNDROME	ASXL1 BRCA2 FANCI	3.62e-03	67	135	3	C3463824
Disease	Malignant neoplasm of breast	TRERF1 GPI ADAMTS1 CYP3A4 DYNC2H1 FAAH NF1 BRCA2 WDCP NLRC5 NCOA1 DOP1A	3.90e-03	1074	135	12	C0006142
Disease	mitochondrial DNA measurement	CARMIL1 SIRPB1 MFN1 NUP205 STIM1 FANCI	4.09e-03	328	135	6	EFO_0006312
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	APOB PLTP	4.12e-03	21	135	2	EFO_0022246
Disease	serum metabolite measurement	CYP3A4 SHBG APOB ABCA7 FAAH AGXT2 PACRGL MROH1 PTCD1 PLCL1 PLTP	4.19e-03	945	135	11	EFO_0005653
Disease	triglycerides to total lipids in small HDL percentage	APOB NLRC5 PLTP	4.44e-03	72	135	3	EFO_0022336

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLPEPLKVIFLVNSG	AGXT2	156	Q9BYV1
PKDPLLFIQLNELLG	SLC4A9	51	Q96Q91
PEALGKLPLHQQLLL	BPIFB3	321	P59826
LNVALDVGIPLPKVL	BPIFB3	436	P59826
IGRLKLLLPDLQPQS	EGFL6	446	Q8IUX8
LLLSPKGEVARALLP	ARHGEF25	526	Q86VW2
LKKLAPPLVTLLSGE	AP2B1	281	P63010
LQVTIALEGPLAPLK	CSPG4	1226	Q6UVK1
LLQALKPIPPLNLET	BHLHE40	396	O14503
AGFLPSLLKVLLLPL	ACRBP	6	Q8NEB7
SLLKVLLLPLAPAAA	ACRBP	11	Q8NEB7
LLSVPKEFLLLGPQQ	GVINP1	206	Q7Z2Y8
IKLNDTLLLGPDPLG	GTPBP1	421	O00178
SLDLLKVFLNILPPL	GTPBP2	381	Q9BX10
AAPFLLGLLTNELPL	IBA57	66	Q5T440
APLKPDLALLAINTL	AP4B1	76	Q9Y6B7
NLILLNKPPEFLLLS	C14orf28	286	Q4W4Y0
LLLLLLPTSGQEKPT	ADGRG3	11	Q86Y34
ILISLLDKPELGPVI	DOP1A	356	Q5JWR5
ILLKDSIQLSLPAPG	DOP1A	1926	Q5JWR5
LLLEKVHQLPPGLLS	DNHD1	1736	Q96M86
LLGEKELPLTSLLPF	C2CD4C	406	Q8TF44
LPGPLALTSLEHKLL	CAMSAP3	156	Q9P1Y5
VDIPGTSKLLLELPL	ARRDC2	286	Q8TBH0
LLQGSLPLEKVLPPA	ASXL1	1111	Q8IXJ9
TQLLQGNLPLEKVLP	ASXL3	1751	Q9C0F0
RLKPLILGKLLFAPD	ABCA7	286	Q8IZY2
IIKLFGALTPLEPRL	AP3D1	241	O14617
LITLPLVGKPLNLDR	NWD1	696	Q149M9
GKGLLPEPNILQLLN	RAVER1	321	Q8IY67
DIPLLQRLLQGPSEK	RASSF6	281	Q6ZTQ3
GPVPTLLLLAAALLA	ADAMTS1	31	Q9UHI8
LNILKALGIVPNLPC	RNF130	306	Q86XS8
PLLSLLAGSLQGKPL	GDF2	11	Q9UK05
LQSLLTPQPPLLKAL	NUP205	1536	Q92621
IIENLKPLLPAGIQD	MFN1	476	Q8IWA4
KLNLPINIIGLAPLC	LAP3	321	P28838
LLPPLKLEACILTQG	FANCI	641	Q9NVI1
LILPIGSIKPLDFSL	FRAS1	1111	Q86XX4
PPRNLLELLINIKAG	ITM2B	176	Q9Y287
GALKRLILNLDPLPT	MMS22L	51	Q6ZRQ5
AKVIQPDGVLLLLPR	MTO1	371	Q9Y2Z2
LKDGLPLPLSQRTLL	HMCN2	3356	Q8NDA2
IGQPLSLLLKNSPLV	MDH2	36	P40926
AQLLDLPLGVKLPVI	FSIP2	46	Q5CZC0
GKLTLIDPETLLPRL	CAND1	956	Q86VP6
TQIPLKLSLGGLLQP	CYP3A4	471	P08684
EVTPLRLELQKLPGL	ISM2	101	Q6H9L7
ALESLALIPLQAPLK	PLTP	401	P55058
ALKNALLPEGIPSLL	MTTP	476	P55157
RKDPLSGLLLLPAAL	EVPL	2001	Q92817
VLLGPPLAGKLVDLT	SLC16A7	386	O60669
PLEKNAPVLLALLGI	GPI	311	P06744
LALLLPPVTLAALVD	QPRT	6	Q15274
LIAALQILLKDPAPE	MROH1	1611	Q8NDA8
QKGLLPLVTILGLPN	HUWE1	796	Q7Z6Z7
LATILPGLPELRKID	NLRC5	1626	Q86WI3
LSQPILLELEAPLKI	PPP1CB	46	P62140
LALDALPPELLVQVL	FBXO17	16	Q96EF6
PQLLEAVLKLLPLDT	FUOM	56	A2VDF0
KTLGLKEVSPLPLNL	DYNC2H1	3696	Q8NCM8
DLTLLDSPIKVPLLL	APOB	2016	P04114
IIPALLQGLLSPDLK	ARMC8	106	Q8IUR7
LLKPDLILLLTVSPE	CMPK2	366	Q5EBM0
LELLVTGLLPKPSLL	IGSF1	1056	Q8N6C5
ILPPLLKDSVAAPLL	KDM1B	206	Q8NB78
GILENLPLLDILKPG	BPIFA1	66	Q9NP55
PLILVGEPSIKRNLL	BRCA2	2276	P51587
LPDVFGLVVLPLELK	FBXO7	326	Q9Y3I1
LQEIPTFQPLLKGLL	BORCS5	56	Q969J3
PLDKLPGLNTATILL	CENPM	6	Q9NSP4
GLQLLAKPELTPLGI	CEMIP2	701	Q9UHN6
PILLLLQVKPLNGSP	LLCFC1	16	Q96L11
IHLPQIPGKLLFSLV	CUL9	246	Q8IWT3
LSPEPLKALLLGLAC	CARMIL1	436	Q5VZK9
LLIGLPSGAILSLPK	EMC1	861	Q8N766
GLLAFLVKPLLPRLS	FAAH	416	O00519
IPPLLGLEKADLLEL	HAUS4	136	Q9H6D7
KLLALDPSPLNVVLL	DNAH2	4176	Q9P225
IALPPKGNIDISLLF	CFAP47	2816	Q6ZTR5
LAPPPLLKDLLRQEL	CCDC24	71	Q8N4L8
DELTPLGRILAKLPI	DHX9	846	Q08211
GKLLLLLPALRSISP	NR2E1	341	Q9Y466
LIGNLLKDLNLSLIP	PCDH11Y	71	Q9BZA8
ELLLVKGAPEKAIPL	PACRGL	141	Q8N7B6
LALVLLLLPAVPVGA	MEGF6	16	O75095
LPIALLLKLRGDPLL	SLC35G5	81	Q96KT7
LPIALLLKLRGDPLL	SLC35G3	81	Q8N808
RVQLISGPPAKLLLI	SMCHD1	1246	A6NHR9
PLLDKLVLPVLPGAL	SFTPB	171	P07988
LEPGRLKLQLASIVP	TMEM191A	66	Q9H0A3
PLVLKATAGLRLLPG	ENTPD6	176	O75354
PLGLLLHPFKDLVQL	SEC24A	406	O95486
QLLPTLEKAAQLPGL	NCOA1	816	Q15788
KFLLLGLIEDPELQP	OR7G2	11	Q8NG99
LSPLVLGQKLGALEP	PRDM8	511	Q9NQV8
LLALLESPKALTPGL	SLC39A4	126	Q6P5W5
LDLPLVLGLPLQLKL	SHBG	296	P04278
LKPLAAALGLALPGL	TAP1	96	Q03518
DLLTLVPPLVGLKGN	SLC41A3	101	Q96GZ6
IPPGVFSKLENLLLL	PRELP	186	P51888
PLLRKQLEGGLALPS	SPATA31C1	406	P0DKV0
TRLPELLQPLEGKNI	MROH2B	551	Q7Z745
LLSQLLAPLPGLLQK	PPP1R15B	66	Q5SWA1
QLKALDTVLFGPPLL	STIM1	191	Q13586
PLPKSGLLLKSQELL	CCDC136	591	Q96JN2
PKPKATLSLLQLGLD	CEP164	1436	Q9UPV0
LPTLVIKLLAPLGLH	CLN3	106	Q13286
LKLPLLVSKLLDIPG	PPCDC	31	Q96CD2
APTAPLLVALLLGPK	SIRPB1	366	O00241
LPIALLLKLRGDPLL	SLC35G4	81	P0C7Q5
KGLLEKAVLLLDFPP	TIGD2	281	Q4W5G0
GLPPIASLKQCLLTL	PLCL1	916	Q15111
LKEEKGLPLALLAPL	TTLL8	656	A6PVC2
GLRPDKPLEAQLLLN	ZFHX2	651	Q9C0A1
LTEHLIPLLPQLLAK	STAG3	576	Q9UJ98
EALLKLGPLPRLLND	SYNGAP1	706	Q96PV0
PGKLPIQLQALSLPL	STAT6	396	P42226
SGLKVILGILLPPSI	TRPM3	796	Q9HCF6
ILGILLPPSILSLEF	TRPM3	801	Q9HCF6
EPLLIRQGLIPKLVS	SYCP2L	101	Q5T4T6
ILALKSLPRGLALGP	ZNF408	51	Q9H9D4
LPPLGSQGLSKEILL	SOGA1	511	O94964
PQDTLKLLPLLTGLF	TMEM79	306	Q9BSE2
RPKDVPGTLLNIALL	NF1	1846	P21359
LELSKLLSRLGQPVP	NDST2	856	P52849
NKPLPVDDILQSLLG	PHF3	1461	Q92576
LQIAGLSLPLPPKKL	PXK	66	Q7Z7A4
TGALKLFLRELPQPL	ARHGAP9	631	Q9BRR9
VLEKLPDLVRGLPTL	SMCO1	91	Q147U7
LPIALLLKLRGDPLL	SLC35G6	81	P0C7Q6
LVLKQNRLGILPSIP	ZSWIM2	431	Q8NEG5
LGFPLLKPAVISQLE	ZNF23	11	P17027
LLKTLLDIPANPTGL	WIPI1	131	Q5MNZ9
IPGILVPDLIAFNLK	WDCP	336	Q9H6R7
ALLPVLAKRGLVPNL	PTCD1	541	O75127
FLLLLLLPAKPAAGE	MST1R	11	Q04912
SLLLTHLPLLKPGNL	SAMD4A	81	Q9UPU9
TLANPLGTLNPLKLL	SCGB3A1	46	Q96QR1
PLKLLLSSLGIPVNH	SCGB3A1	56	Q96QR1
LPLLLPVLGAGSLNK	SIGLEC11	16	Q96RL6
APGLLPLDQLSLIKP	TRERF1	1141	Q96PN7
DVGLPKPDLVLFLQL	DTYMK	121	P23919
LVPELIKELNSLGRP	MMUT	681	P22033