Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Glyco_hydro_31_CS	MGAM SI	1.59e-04	4	97	2	IPR030459
Domain	NtCtMGAM_N	MGAM SI	1.59e-04	4	97	2	PF16863
Domain	Gal_mutarotase_N	MGAM SI	1.59e-04	4	97	2	IPR031727
Domain	PLAT	DENND5B LIPC DENND5A	1.69e-04	21	97	3	PS50095
Domain	-	DENND5B LIPC DENND5A	1.69e-04	21	97	3	2.60.60.20
Domain	PLAT	DENND5B LIPC DENND5A	1.69e-04	21	97	3	PF01477
Domain	PLAT/LH2_dom	DENND5B LIPC DENND5A	1.69e-04	21	97	3	IPR001024
Domain	GLYCOSYL_HYDROL_F31_2	MGAM SI	2.64e-04	5	97	2	PS00707
Domain	Glyco_hydro_31_AS	MGAM SI	3.95e-04	6	97	2	IPR030458
Domain	Glyco_hydro_31	MGAM SI	5.51e-04	7	97	2	IPR000322
Domain	Glyco_hydro_31	MGAM SI	5.51e-04	7	97	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM SI	5.51e-04	7	97	2	PS00129
Domain	Trefoil	MGAM SI	7.32e-04	8	97	2	PF00088
Domain	P_TREFOIL_1	MGAM SI	7.32e-04	8	97	2	PS00025
Domain	P_trefoil_CS	MGAM SI	7.32e-04	8	97	2	IPR017957
Domain	P_TREFOIL_2	MGAM SI	9.39e-04	9	97	2	PS51448
Domain	PD	MGAM SI	9.39e-04	9	97	2	SM00018
Domain	-	MGAM SI	1.42e-03	11	97	2	4.10.110.10
Domain	BAH	DNMT1 BAHCC1	1.42e-03	11	97	2	SM00439
Domain	BAH	DNMT1 BAHCC1	1.42e-03	11	97	2	PF01426
Domain	BAH	DNMT1 BAHCC1	1.42e-03	11	97	2	PS51038
Domain	BAH_dom	DNMT1 BAHCC1	1.42e-03	11	97	2	IPR001025
Domain	P_trefoil_dom	MGAM SI	1.70e-03	12	97	2	IPR000519
Domain	FERM_M	FRMD8 NF2 EPB41	1.75e-03	46	97	3	PF00373
Domain	-	FRMD8 NF2 EPB41	2.10e-03	49	97	3	1.20.80.10
Domain	FERM_central	FRMD8 NF2 EPB41	2.10e-03	49	97	3	IPR019748
Domain	FERM_domain	FRMD8 NF2 EPB41	2.10e-03	49	97	3	IPR000299
Domain	FERM_1	FRMD8 NF2 EPB41	2.23e-03	50	97	3	PS00660
Domain	FERM_2	FRMD8 NF2 EPB41	2.23e-03	50	97	3	PS00661
Domain	FERM_3	FRMD8 NF2 EPB41	2.23e-03	50	97	3	PS50057
Domain	Band_41_domain	FRMD8 NF2 EPB41	2.23e-03	50	97	3	IPR019749
Domain	B41	FRMD8 NF2 EPB41	2.23e-03	50	97	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	FRMD8 NF2 EPB41	2.23e-03	50	97	3	IPR014352
Domain	uDENN	DENND5B DENND5A	2.33e-03	14	97	2	SM00800
Domain	uDENN	DENND5B DENND5A	2.68e-03	15	97	2	PF03456
Domain	UDENN	DENND5B DENND5A	3.06e-03	16	97	2	PS50946
Domain	DDENN	DENND5B DENND5A	3.06e-03	16	97	2	PS50947
Domain	DENN	DENND5B DENND5A	3.06e-03	16	97	2	SM00799
Domain	dDENN	DENND5B DENND5A	3.06e-03	16	97	2	SM00801
Domain	DENN	DENND5B DENND5A	3.06e-03	16	97	2	PF02141
Domain	dDENN_dom	DENND5B DENND5A	3.06e-03	16	97	2	IPR005112
Domain	uDENN_dom	DENND5B DENND5A	3.06e-03	16	97	2	IPR005113
Domain	dDENN	DENND5B DENND5A	3.06e-03	16	97	2	PF03455
Domain	DENN	DENND5B DENND5A	3.06e-03	16	97	2	PS50211
Domain	DENN_dom	DENND5B DENND5A	3.06e-03	16	97	2	IPR001194
Domain	Gal_mutarotase_SF_dom	MGAM SI	3.45e-03	17	97	2	IPR011013
Domain	RUN	DENND5B DENND5A	3.87e-03	18	97	2	SM00593
Domain	RUN	DENND5B DENND5A	4.31e-03	19	97	2	PS50826
Domain	RUN	DENND5B DENND5A	4.31e-03	19	97	2	PF02759
Domain	Run_dom	DENND5B DENND5A	4.31e-03	19	97	2	IPR004012
Domain	P-loop_NTPase	WSCD1 SMARCAL1 DDX42 PEX1 CHD9 LRRK1 RFC4 KIF20A ABCA5 IQCB1 ASPM	4.49e-03	848	97	11	IPR027417
Pubmed	Mapping the interactions between a RUN domain from DENND5/Rab6IP1 and sorting nexin 1.	DENND5A SNX1	8.18e-06	2	100	2	22558185
Pubmed	Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients.	CYP2E1 CYP3A4	8.18e-06	2	100	2	17119944
Pubmed	Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation.	CYP2E1 CYP3A4	8.18e-06	2	100	2	23530020
Pubmed	High Maternal Serum Estradiol in First Trimester of Multiple Pregnancy Contributes to Small for Gestational Age via DNMT1-Mediated CDKN1C Upregulation.	CDKN1C DNMT1	8.18e-06	2	100	2	34580843
Pubmed	Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.	MGAM SI	8.18e-06	2	100	2	36968271
Pubmed	Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways.	TRPV1 PRKCA	8.18e-06	2	100	2	12095983
Pubmed	Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.	MGAM SI	8.18e-06	2	100	2	27480812
Pubmed	An NH2-terminal truncated cytochrome P450 CYP3A4 showing catalytic activity is present in the cytoplasm of human liver cells.	CYP2E1 CYP3A4	8.18e-06	2	100	2	18446064
Pubmed	Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.	MGAM SI	8.18e-06	2	100	2	20356844
Pubmed	Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site.	TRPV1 PRKCA	8.18e-06	2	100	2	25734989
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RPF1 DCAF13 HEATR1 URB2 RFC4 ECT2 TTF1 IQCB1 ASPM NOP2 DNMT1	1.21e-05	759	100	11	35915203
Pubmed	Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure.	CYP2E1 CYP3A4	2.45e-05	3	100	2	23775837
Pubmed	Partial characterization of murine intestinal maltase-glucoamylase.	MGAM SI	2.45e-05	3	100	2	12150962
Pubmed	Regulation of human glioma cell apoptosis and invasion by miR-152-3p through targeting DNMT1 and regulating NF2 : MiR-152-3p regulate glioma cell apoptosis and invasion.	NF2 DNMT1	2.45e-05	3	100	2	28764788
Pubmed	Retinal Development and Pathophysiology in Kcnj13 Knockout Mice.	KCNJ13 PRKCA	2.45e-05	3	100	2	35096838
Pubmed	A genome-wide study of inherited deletions identified two regions associated with nonsyndromic isolated oral clefts.	MGAM ADAM5	2.45e-05	3	100	2	25776870
Pubmed	Heat-induced MMP-1 expression is mediated by TRPV1 through PKCalpha signaling in HaCaT cells.	TRPV1 PRKCA	2.45e-05	3	100	2	18503554
Pubmed	Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration.	CEMIP PRKCA	2.45e-05	3	100	2	23990668
Pubmed	Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease.	PRKCA DNMT1	2.45e-05	3	100	2	34482802
Pubmed	ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells.	CEMIP PRKCA	2.45e-05	3	100	2	35013120
Pubmed	Cytochrome p450 and glutathione transferase expression in human breast cancer.	CYP2E1 CYP3A4	4.89e-05	4	100	2	12738724
Pubmed	Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells.	CYP2E1 CYP3A4	4.89e-05	4	100	2	17007050
Pubmed	Heat induces interleukin-6 in skeletal muscle cells via TRPV1/PKC/CREB pathways.	TRPV1 PRKCA	4.89e-05	4	100	2	27979980
Pubmed	Cytochrome P450 levels are altered in patients with esophageal squamous-cell carcinoma.	CYP2E1 CYP3A4	4.89e-05	4	100	2	17373732
Pubmed	Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism.	CYP2E1 CYP3A4	4.89e-05	4	100	2	18211048
Pubmed	Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.	NF2 PRKCA	4.89e-05	4	100	2	21750658
Pubmed	Genetic polymorphisms in cytochrome P450 genes are associated with an increased risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.	CYP2E1 CYP3A4	4.89e-05	4	100	2	19963139
Pubmed	p57(Kip2) cooperates with Nurr1 in developing dopamine cells.	CDKN1C NR4A2	4.89e-05	4	100	2	14671317
Pubmed	[Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer].	CYP2E1 CYP3A4	4.89e-05	4	100	2	34238413
Pubmed	Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.	CYP2E1 CYP3A4	4.89e-05	4	100	2	25319358
Pubmed	The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.	KIF20A SUN2	4.89e-05	4	100	2	33686165
Pubmed	Novel genes differentially expressed in cortical regions during late neurogenesis.	WSCD1 NR4A2 TENM3	7.17e-05	28	100	3	17614941
Pubmed	Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures.	CYP2E1 CYP3A4	8.14e-05	5	100	2	29125184
Pubmed	CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer.	CYP2E1 CYP3A4	8.14e-05	5	100	2	12569554
Pubmed	Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone.	CYP2E1 CYP3A4	8.14e-05	5	100	2	8006463
Pubmed	The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting.	CDKN1C DNMT1	8.14e-05	5	100	2	28943313
Pubmed	A Unique "Reversed" Migration of Neurons in the Developing Claustrum.	VLDLR NR4A2	8.14e-05	5	100	2	36631266
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	DDX42 HEATR1 KIF20A ASPM SNX1 EPB41	1.00e-04	256	100	6	33397691
Pubmed	The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia.	CYP2E1 CYP3A4	1.22e-04	6	100	2	17118447
Pubmed	Prediction of genetic risk for dyslipidemia.	CYP3A4 LIPC	1.22e-04	6	100	2	17919884
Pubmed	Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes.	CYP2E1 CYP3A4	1.22e-04	6	100	2	16401082
Pubmed	Upregulation of CYP2e1 and CYP3a activities in histamine-deficient histidine decarboxylase gene targeted mice.	CYP2E1 CYP3A4	1.22e-04	6	100	2	14642533
Pubmed	Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first- and third-generation Japanese populations: comparison with Korean, Chinese, and Caucasian populations.	CYP2E1 CYP3A4	1.22e-04	6	100	2	18231117
Pubmed	Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.	PTGDS NF2	1.70e-04	7	100	2	21242963
Pubmed	Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice.	CYP2E1 CYP3A4	1.70e-04	7	100	2	30944282
Pubmed	Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction.	CYP3A4 PRKCA	1.70e-04	7	100	2	22101235
Pubmed	Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination.	CYP2E1 CYP3A4	1.70e-04	7	100	2	21209460
Pubmed	Association between genetic polymorphisms in styrene-metabolizing enzymes and biomarkers in styrene-exposed workers.	CYP2E1 CYP3A4	1.70e-04	7	100	2	18569587
Pubmed	Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes.	CYP2E1 CYP3A4	1.70e-04	7	100	2	19219744
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	HEATR1 ASH2L NF2 SH3D19 PEAK1 SNX1 EPB41 DNMT1	1.91e-04	549	100	8	38280479
Pubmed	CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.	ASH2L DNMT1	2.27e-04	8	100	2	18680430
Pubmed	Profile of polymorphisms of drug-metabolising enzymes and the risk of therapy-related leukaemia.	CYP2E1 CYP3A4	2.27e-04	8	100	2	17367411
Pubmed	Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.	CYP2E1 CYP3A4	2.27e-04	8	100	2	18356043
Pubmed	Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes.	CYP2E1 CYP3A4	2.27e-04	8	100	2	15680923
Pubmed	Structural diversity of band 4.1 superfamily members.	NF2 EPB41	2.27e-04	8	100	2	7983158
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ELFN2 TENM3 NF2 SH3D19 PPME1 PEAK1 SNX1 EPB41	2.32e-04	565	100	8	25468996
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	RPF1 DCAF13 MBNL1 DDX42 RBM42 ASH2L KIF20A SUN2 NOP2	2.44e-04	723	100	9	34133714
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	HEATR1 RFC4 TENM3 NF2 IQCB1 DENND5A	2.45e-04	302	100	6	30561431
Pubmed	The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network.	DENND5A SNX1	2.91e-04	9	100	2	19619496
Pubmed	The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.	VLDLR MGAM	2.91e-04	9	100	2	25857663
Pubmed	A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA.	CDKN1C DNMT1	2.91e-04	9	100	2	17245608
Pubmed	Functional proteomics mapping of a human signaling pathway.	PPP1R3B CILK1 TTF1 ASH2L ZNF518A FMNL3 TENM3 ZNF587	3.14e-04	591	100	8	15231748
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	CENPL DBF4B PEX1 HEATR1 RFC4 ESYT3 SLC9A2 NOP2 SNX1	3.32e-04	754	100	9	35906200
Pubmed	GABAergic amacrine cells and visual function are reduced in PAC1 transgenic mice.	CDKN1C PRKCA	3.63e-04	10	100	2	19596361
Pubmed	Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.	ASH2L NF2	3.63e-04	10	100	2	20937768
Pubmed	Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum.	VLDLR LHX5	3.63e-04	10	100	2	20809939
Pubmed	Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease.	CYP2E1 CYP3A4	3.63e-04	10	100	2	19651758
Pubmed	Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner.	CDKN1C CYP3A4	3.63e-04	10	100	2	26165599
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DDX42 HEATR1 RFC4 SH3D19 SENP6 PPME1 NOP2 SNX1 EPB41 DNMT1	3.64e-04	934	100	10	33916271
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	CENPL PEX1 NF2 SUN2 HSD17B13 ASPM	3.69e-04	326	100	6	17015433
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	VLDLR PEX1 CHD9 ZKSCAN2 RFC4 ZNF518A KIF20A SUN2 ASPM TAF11 BAHCC1	3.70e-04	1116	100	11	31753913
Pubmed	Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.	DBF4B LRRK1 MLLT3	4.35e-04	51	100	3	24510904
Pubmed	Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.	CDKN1C DNMT1	4.43e-04	11	100	2	15516931
Pubmed	Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.	CYP2E1 CYP3A4	4.43e-04	11	100	2	15469410
Pubmed	The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.	CDKN1C NF2	4.43e-04	11	100	2	20181838
Pubmed	Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.	CYP2E1 CYP3A4	4.43e-04	11	100	2	15039299
Pubmed	The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.	ASPM PRKCA	5.30e-04	12	100	2	22031545
Pubmed	Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.	CDKN1C DNMT1	5.30e-04	12	100	2	27824296
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CILK1 ELFN2 TSC22D1 CMIP SACS SUN2 PEAK1	5.68e-04	493	100	7	15368895
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RPF1 DCAF13 DDX42 HEATR1 URB2 RFC4 ECT2 KIF20A NOP2 DNMT1	5.68e-04	989	100	10	36424410
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	NRDE2 PEX1 ECT2 ASH2L CEMIP CARD6 DENND5A DNMT1	5.87e-04	650	100	8	38777146
Pubmed	Characterization of Olig2 expression during cerebellar development.	CDKN1C LHX5	6.25e-04	13	100	2	24594479
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	SUN2 PRKCA	6.25e-04	13	100	2	21177258
Pubmed	WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.	ECT2 ASH2L	6.25e-04	13	100	2	25666610
Pubmed	Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo.	CDKN1C DNMT1	6.25e-04	13	100	2	21354127
Pubmed	Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1.	CDKN1C DNMT1	6.25e-04	13	100	2	20573698
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	NRDE2 MBNL1 ECT2 NF2 ASPM LARGE1	6.49e-04	363	100	6	14691545
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DCAF13 IPP RFC4 ECT2 ASH2L SUN2 ASPM NOP2	7.15e-04	670	100	8	22990118
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	RPF1 KCTD9 MBNL1 RBM42 RFC4 CATSPER1 ARHGEF3	7.25e-04	514	100	7	29892012
Pubmed	A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.	CYP2E1 CYP3A4	7.28e-04	14	100	2	18258609
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	VLDLR SACS	7.28e-04	14	100	2	15082773
Pubmed	Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival.	PRKCA DNMT1	7.28e-04	14	100	2	23171847
Pubmed	Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter.	VLDLR PTGDS	7.28e-04	14	100	2	2034277
Pubmed	FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.	RPF1 DDX42 URB2 ASH2L DNMT1	7.68e-04	248	100	5	27926873
Pubmed	Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.	VLDLR NR4A2	8.39e-04	15	100	2	24449842
Pubmed	Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility.	CYP2E1 CYP3A4	8.39e-04	15	100	2	19575027
Pubmed	Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.	TSC22D1 PEAK1	8.39e-04	15	100	2	12056414
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	RFC4 KIF20A NOP2 DNMT1	9.22e-04	149	100	4	25184681
Pubmed	Otx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic Neurons.	NR4A2 LHX5	9.57e-04	16	100	2	26444681
Pubmed	Role of topoisomerase IIbeta in the expression of developmentally regulated genes.	PTGDS TENM3	9.57e-04	16	100	2	16923961
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMD8 NF2 EPB41	7.03e-04	50	63	3	1293
Coexpression	FISCHER_G2_M_CELL_CYCLE	KCTD9 CENPL DBF4B ECT2 ZNF518A CEMIP KIF20A ZNF587 ASPM	3.12e-07	236	100	9	M130
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	DCAF13 CENPL HEATR1 URB2 RFC4 ECT2 KIF20A ASPM NOP2 DNMT1	2.80e-11	199	100	10	38f1f612b29feb868322999ceeda78e52447ec4f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma\|TCGA-Stomach / Sample_Type by Project: Shred V9	DCAF13 CENPL HEATR1 URB2 RFC4 ECT2 KIF20A ASPM NOP2 DNMT1	2.80e-11	199	100	10	b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS CENPL ECT2 KIF20A ASPM DNMT1	3.62e-06	183	100	6	769a022fe8568ec49e66f792cc5777e713a7571c
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS CENPL ECT2 KIF20A ASPM DNMT1	3.62e-06	183	100	6	aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDKN1C KCTD9 PPP1R3B PEX1 ASH2L ZNF417	4.10e-06	187	100	6	c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CENPL DBF4B ECT2 KIF20A SUN2 ASPM	4.63e-06	191	100	6	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CENPL DBF4B ECT2 KIF20A SUN2 ASPM	4.77e-06	192	100	6	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CENPL DBF4B ECT2 KIF20A SUN2 ASPM	4.77e-06	192	100	6	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CENPL DBF4B ECT2 KIF20A SUN2 ASPM	4.77e-06	192	100	6	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL RFC4 ECT2 KIF20A ASPM DNMT1	5.37e-06	196	100	6	5ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell	droplet-Trachea\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C NR4A2 COQ10B CEMIP TSC22D1 TENM3	5.86e-06	199	100	6	1c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell	droplet-Trachea\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C NR4A2 COQ10B CEMIP TSC22D1 TENM3	5.86e-06	199	100	6	b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPL RFC4 ECT2 KIF20A ASPM DNMT1	6.03e-06	200	100	6	1fbed5967fc1922efe4a98f5760ad74fce210c52
ToppCell	Endothelial-Endothelial-H_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	ECT2 KIF20A SUN2 KCNJ13 ASPM	1.50e-05	138	100	5	a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	COQ10B PTGDS PPME1 MCTP2	1.88e-05	70	100	4	37e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRDE2 CENPL ECT2 KIF20A ASPM	1.97e-05	146	100	5	45d7cb73776e60d22f335a651845e21e16948fcc
ToppCell	facs-Trachea-nan-18m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS35 CDKN1C MATN3 PTGDS CEMIP	3.76e-05	167	100	5	7b1fd19946cee67dae68f0f0d98420abcd532482
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRSS35 CDKN1C MATN3 PTGDS CEMIP	3.76e-05	167	100	5	102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell	BAL-Control-cDC_6\|Control / Compartment, Disease Groups and Clusters	VLDLR NR4A2 CEMIP KIF20A ASPM	3.87e-05	168	100	5	65ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	VLDLR MSC KCNJ13 ASPM ZNF417	3.87e-05	168	100	5	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CENPL ECT2 KIF20A ASPM DNMT1	3.98e-05	169	100	5	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2E1 TSC22D1 ABCA5 PRKCA MCTP2	4.21e-05	171	100	5	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2E1 TSC22D1 ABCA5 PRKCA MCTP2	4.21e-05	171	100	5	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 ABCA5 PRKCA SLC25A53 MCTP2	4.45e-05	173	100	5	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 ABCA5 PRKCA SLC25A53 MCTP2	4.45e-05	173	100	5	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MATN3 PTGDS CEMIP ESYT3 BAHCC1	4.70e-05	175	100	5	aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Striatum / BrainAtlas - Mouse McCarroll V32	CENPL RFC4 ECT2 KIF20A ASPM	4.82e-05	176	100	5	d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1\|Striatum / BrainAtlas - Mouse McCarroll V32	CENPL RFC4 ECT2 KIF20A ASPM	4.82e-05	176	100	5	a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPL ECT2 KIF20A SUN2 ASPM	4.82e-05	176	100	5	8385435074cc5235b7af7424974f609388fc2cff
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLPPR5 ECT2 KIF20A TENM3 ASPM	4.96e-05	177	100	5	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	MATN3 BRME1 PTGDS ASPM ARHGEF3	5.09e-05	178	100	5	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBNL1 CHD9 TSC22D1 PRKCA MCTP2	5.23e-05	179	100	5	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBNL1 CHD9 TSC22D1 PRKCA MCTP2	5.23e-05	179	100	5	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C VLDLR MSC PPP1R3B CHD9	5.37e-05	180	100	5	e9785ac2806103f725f5a5208495826354ec6e22
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL RFC4 ECT2 KIF20A ASPM	5.51e-05	181	100	5	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL RFC4 ECT2 KIF20A ASPM	5.51e-05	181	100	5	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CENPL DBF4B ECT2 KIF20A ASPM	5.66e-05	182	100	5	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	DBF4B RFC4 ECT2 KIF20A ASPM	5.66e-05	182	100	5	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBNL1 NR4A2 CHD9 SENP6 PEAK1	5.66e-05	182	100	5	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	Immune_cells-Dendritic_cells\|Immune_cells / Lineage and Cell class	TMED3 TSC22D1 ABCA5 PRKCA MCTP2	5.66e-05	182	100	5	99c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBNL1 NR4A2 CHD9 SENP6 PEAK1	5.66e-05	182	100	5	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THEMIS LRRK1 SLC22A24 CEMIP EPB41	5.96e-05	184	100	5	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS SACS SUN2 PRKCA SLC25A53	5.96e-05	184	100	5	2c8e9ddce3e60302965dcf9dee77c4fe33e4071d
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THEMIS CENPL ECT2 KIF20A ASPM	6.11e-05	185	100	5	0e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THEMIS CENPL ECT2 KIF20A ASPM	6.11e-05	185	100	5	89b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCell	(1)_T_CD4_naive\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	THEMIS MBNL1 PRKCA MLLT3 EPB41	6.59e-05	188	100	5	b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRSS35 CENPL ECT2 KIF20A ASPM	6.59e-05	188	100	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPL RFC4 ECT2 KIF20A ASPM	6.59e-05	188	100	5	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RFX6 ECT2 KIF20A USP44 SLC9A2	6.76e-05	189	100	5	a6c62b456982067ad4d224a2efa3919969000693
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL ECT2 KIF20A ASPM DNMT1	6.93e-05	190	100	5	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPL ECT2 KIF20A SUN2 ASPM	6.93e-05	190	100	5	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRSS35 CDKN1C PLPPR5 TMED3 TENM3	7.11e-05	191	100	5	053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RFC4 ECT2 KIF20A ASPM DNMT1	7.11e-05	191	100	5	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL RFC4 ECT2 KIF20A ASPM	7.28e-05	192	100	5	5ef79faddb433c09ff36660d8bf7a3af5a67bf1d
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND5B CMIP SH3D19 PRKCA LARGE1	7.28e-05	192	100	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRSS35 CENPL ECT2 KIF20A ASPM	7.46e-05	193	100	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	droplet-Tongue-nan-3m-Epithelial-proliferating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL RFC4 ECT2 KIF20A ASPM	7.65e-05	194	100	5	2cac1b9c4da01faaec9a67ec06f47a7060760225
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	MATN3 PTGDS ECT2 KIF20A ASPM	7.65e-05	194	100	5	c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCell	P15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRSS35 CDKN1C CYP2E1 NR4A2 COQ10B	7.65e-05	194	100	5	5f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL RFC4 ECT2 KIF20A DNMT1	7.83e-05	195	100	5	7ae732f100e9a3c6062be5b877efa1ec9d5b3958
ToppCell	(0)_NK/T_cells-(0)_NK_T_CD8_Cytotoxic\|(0)_NK/T_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	KCTD9 PPP1R3B TSC22D1 CATSPER1 MCTP2	7.83e-05	195	100	5	13717c6e42882162445bc1b1445d66efcb68e19d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPL ECT2 KIF20A SUN2 ASPM	7.83e-05	195	100	5	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RFC4 ECT2 KIF20A ASPM DNMT1	7.83e-05	195	100	5	043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell	E17.5-Mesenchymal\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDKN1C VLDLR TSC22D1 PRKCA PEAK1	8.03e-05	196	100	5	b4ee991445b612506372b9361ebfe72cb59b811e
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL RFC4 ECT2 KIF20A ASPM	8.03e-05	196	100	5	62b2de1d38a99ab23211bf51595845f8a1fdb7d2
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL RFC4 ECT2 KIF20A ASPM	8.22e-05	197	100	5	f84f0ddf51208764ab56408d97035bbff562e59d
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL RFC4 ECT2 KIF20A DNMT1	8.22e-05	197	100	5	a0d463825b62de49466f9fa563405dda4387cfff
ToppCell	(0)_NK_FCGR3Apos\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PTGDS CATSPER1 SUN2 ARHGEF3 MCTP2	8.42e-05	198	100	5	13f10f9233fc1523f0da2d9d59f3ced9c51a603a
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPL ECT2 KIF20A SUN2 ASPM	8.42e-05	198	100	5	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL RFC4 ECT2 KIF20A ASPM	8.42e-05	198	100	5	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL RFC4 ECT2 KIF20A ASPM	8.42e-05	198	100	5	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	RFC4 ECT2 KIF20A ASPM DNMT1	8.42e-05	198	100	5	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C MATN3 CEMIP TSC22D1 PRKCA	8.42e-05	198	100	5	3575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RFC4 ECT2 KIF20A ASPM DNMT1	8.42e-05	198	100	5	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CDKN1C PTGDS CEMIP SH3D19 PEAK1	8.62e-05	199	100	5	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CDKN1C PTGDS CEMIP SH3D19 PEAK1	8.62e-05	199	100	5	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	distal-Hematologic-Proliferating_Macrophage\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL RFC4 ECT2 KIF20A ASPM	8.83e-05	200	100	5	3835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCell	Control-Control-Lymphocyte-T/NK-T/NK_proliferative\|Control / Disease, condition lineage and cell class	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	6cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS MSC RFC4 KIF20A ASPM	8.83e-05	200	100	5	562309f9ca4a73cea5ed1d85b516891545f3ae5f
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MSC ZKSCAN2 PTGDS TENM3 PRKCA	8.83e-05	200	100	5	f692b602bc989d35c9162e73dda813dbef8d5267
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	THEMIS PRKCA MLLT3 ARHGEF3 EPB41	8.83e-05	200	100	5	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells-Neuroepithelial_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	55501f83409e0174c756a13ad8077f5b59975e27
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells\|6m / Sample Type, Dataset, Time_group, and Cell type.	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	b9aad527d3ad5bc701e93fa2afdebf695b2a74bb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells\|1m / Sample Type, Dataset, Time_group, and Cell type.	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	13636463e44a99cd886926340bfb35880f95cca6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells-Neuroepithelial_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	2a3874634cc4357a64ef9fd4a6bbdfd84236ebac
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RFC4 ECT2 KIF20A ASPM DNMT1	8.83e-05	200	100	5	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DENND5B SACS SH3D19 PRKCA	1.36e-04	116	100	4	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	THEMIS CYP2E1 ELFN2 CEMIP	2.11e-04	130	100	4	3709d17044d48b120effd8ba4104ca81c49d7e19
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	MGAM SI RFX6 LIPC	3.03e-04	143	100	4	bcf702f976ab91f82a5a4beb0b7c74a372c42ae6
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	WSCD1 SPEG SACS ZNF839	3.19e-04	145	100	4	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	IIH-CD8-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	TRPV1 CENPL TTF1 USP44	3.28e-04	146	100	4	7fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMARCAL1 RFC4 SACS KCNJ13	3.63e-04	150	100	4	c2c51a3230c978e2fdb1b3ae14193d4014431b25
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C CILK1 ELFN2 LARGE1	3.91e-04	153	100	4	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	PPP1R3B ASH2L LIPC ZNF587	4.01e-04	154	100	4	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECT2 ESYT3 ASPM MCTP2	4.31e-04	157	100	4	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MATN3 LRRK1 PTGDS CEMIP	4.52e-04	159	100	4	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPP FRMD8 HSD17B13 LARGE1	4.52e-04	159	100	4	709b57f992a29878cc899d760d144d36cb5cb280
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS NF2 ASPM MLLT3	4.52e-04	159	100	4	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
Disease	endoplasmin measurement	TTC41P ARHGEF3	6.26e-05	4	96	2	EFO_0801570
Disease	Disproportionate short stature	CDKN1C MATN3 SMARCAL1 CILK1	1.19e-04	77	96	4	C0878659
Disease	triglyceride measurement, multiple sclerosis	IQCB1 ARHGEF3	2.18e-04	7	96	2	EFO_0004530, MONDO_0005301
Disease	Asthma, Occupational	TENM3 PRKCA	4.63e-04	10	96	2	C0264423
Disease	Alpha ketoglutarate measurement	VLDLR TENM3	1.22e-03	16	96	2	EFO_0010457
Disease	gut microbiome measurement, taxonomic microbiome measurement	NRDE2 TMCO5A SLC9A2	1.32e-03	66	96	3	EFO_0007874, EFO_0007883
Disease	ischemia (biomarker_via_orthology)	LIPC PRKCA	1.55e-03	18	96	2	DOID:326 (biomarker_via_orthology)
Disease	Non-alcoholic Fatty Liver Disease	VLDLR CYP2E1 PRKCA	1.56e-03	70	96	3	C0400966
Disease	Nonalcoholic Steatohepatitis	VLDLR CYP2E1 PRKCA	1.56e-03	70	96	3	C3241937
Disease	etiocholanolone glucuronide measurement	CYP3A4 SLC22A24	1.73e-03	19	96	2	EFO_0800362
Disease	leprosy, Crohn's disease	SLC9A2 LACC1	1.92e-03	20	96	2	EFO_0000384, EFO_0001054
Disease	androsterone glucuronide measurement	CYP3A4 SLC22A24	1.92e-03	20	96	2	EFO_0800317
Disease	dilated cardiomyopathy	FMNL3 PRKCA	1.92e-03	20	96	2	EFO_0000407
Disease	epilepsy (biomarker_via_orthology)	NR4A2 NF2	2.11e-03	21	96	2	DOID:1826 (biomarker_via_orthology)
Disease	Leber Congenital Amaurosis	KCNJ13 IQCB1	2.32e-03	22	96	2	C0339527
Disease	Schizophrenia	CDKN1C VLDLR CYP2E1 CYP3A4 MBNL1 NR4A2 PRKCA MCTP2 DNMT1	2.35e-03	883	96	9	C0036341
Disease	otosclerosis	FMNL3 PEAK1 DNMT1	2.37e-03	81	96	3	EFO_0004213
Disease	Hodgkins lymphoma	THEMIS BRME1 ESYT3	2.45e-03	82	96	3	EFO_0000183
Disease	Renal glomerular disease	CDKN1C SMARCAL1	2.53e-03	23	96	2	C0268731
Disease	Glomerulopathy Assessment	CDKN1C SMARCAL1	2.53e-03	23	96	2	C4521256
Disease	urate measurement	TMCO5A CYP3A4 FRMD8 ZKSCAN2 CEMIP LIPC CMIP MLLT3 LARGE1	2.57e-03	895	96	9	EFO_0004531
Disease	inflammatory bowel disease (implicated_via_orthology)	THEMIS EPB41	2.99e-03	25	96	2	DOID:0050589 (implicated_via_orthology)
Disease	sensory perception of bitter taste	MGAM MCTP2	3.24e-03	26	96	2	GO_0050913

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPTQKTARLFSKKIF	TMCO5A	211	Q8N6Q1
FIPNIKDRATSTIKR	TTF1	501	Q15361
LNFRKITAFLSSSKP	URB2	1021	Q14146
SIRKDPFFRNLSTKS	ABCA5	1236	Q8WWZ7
PFFRNLSTKSKNRKL	ABCA5	1241	Q8WWZ7
PKIREKSIHLRTFTF	ESYT3	146	A0FGR9
RLFSSFLKRPKSQVS	EPB41	81	P11171
LSFSKAKELSRRQRP	BAHCC1	2451	Q9P281
RKSSEKTDFIKLFPR	ADAM5	136	Q6NVV9
KATPLKRFSQTLQRS	ARHGEF3	56	Q9NR81
RKSDPKRFQNIFTTI	CATSPER1	606	Q8NEC5
FTFNIKLSSPVKRPR	DNMT1	946	P26358
ARTFFKITAPLINKR	COQ10B	61	Q9H8M1
KLTFNNPTEDFRRKL	MLLT3	121	P42568
RKLKRELPFSFRSIN	GSDMB	136	Q8TAX9
RHPRTFLSKILTSKF	CMIP	66	Q8IY22
FRSLAASSPSIRQKK	CCDC70	26	Q6NSX1
SLVKFFIPQRRKSVA	HSD17B13	21	Q7Z5P4
KDKRPFLSIISARYS	CEMIP	751	Q8WUJ3
SFDKSIRIFPVDKSR	DCAF13	301	Q9NV06
DLSIFRTPISKTNKR	ASPM	641	Q8IZT6
TKKARSDPLFSAQRL	ASH2L	311	Q9UBL3
FSRFPSFLKAKVIRD	RBM42	401	Q9BTD8
FGKTIRQKFPLLTTR	RFX6	166	Q8HWS3
KNIPKSFTRLAQRFG	CYP2E1	51	P05181
FSFSKTPKRALRRAL	ECT2	841	Q9H8V3
FCSFLQTSKVRPRKK	IPP	271	Q9Y573
NFLRGRPKTFKSLEN	PPME1	196	Q9Y570
SRKEFVRFLLATPTK	KCTD9	201	Q7L273
RYRLSFPKSKAELLS	LARGE1	601	O95461
SRSVRPLEFTKVKTF	MATN3	91	O15232
VKASIRTFTPREKRF	MCTP2	631	Q6DN12
LKTKRIAFFTTRGRQ	LRRK1	516	Q38SD2
RVKPKRTTSFFSRQL	FRMD8	431	Q9BZ67
EAAKTVFPNKRSFIL	MGAM	596	O43451
PQKFFRKVESRISDK	DDX58	456	O95786
FPREVTNFLRKSVKR	CYP3A4	241	P08684
DRQTLLFSATFRKKI	DDX42	431	Q86XP3
RARKTFPSKEAALSV	PLPPR5	186	Q32ZL2
RANTLSPVRFFVDKK	PEAK1	276	Q9H792
KTRRFFDTITRSAKP	NRDE2	1016	Q9H7Z3
FVAKIARPKNRAFSI	KCNJ13	156	O60928
NLFSSSKRRDPKVVV	LACC1	211	Q8IV20
SKRLFLVTRAQSPFK	LIPC	336	P11150
ISPSDLVRKARSKVF	LHX5	71	Q9H2C1
FSSLKRKQPKTFTVR	NF2	11	P35240
RKQTRPFSATKDELA	CHD9	1451	Q3L8U1
RFVPQFAKSRKTVTR	BRME1	101	Q0VDD7
DRSRKVLPDFVKQFS	CARD6	296	Q9BX69
PLQKRLESVRKQSSF	CENPL	26	Q8N0S6
LISDFFAKRKRSAPE	CDKN1C	271	P49918
AESRTRKVARLKAPF	DBF4B	216	Q8NFT6
LQSFLDPSVTRKKFR	FMNL3	86	Q8IVF7
LFYESRITLKKPSNR	IDI2-AS1	101	Q9NZ38
FDQSPLRRTFKSKVL	DENND5B	46	Q6ZUT9
QTPLRRTFKSKVLAR	DENND5A	66	Q6IQ26
QSAVKSLKRPLEATF	MBNL1	271	Q9NR56
ELFLSRSRPVAAKAK	IQCB1	536	Q15051
LKTRDSSPKVRFAAL	HEATR1	2071	Q9H583
SVLQTFDAKRPKFLT	SACS	3161	Q9NZJ4
LIQPKTRRAKENTFS	PEX1	176	O43933
SLRQERFAFKISPKP	PPP1R3B	16	Q86XI6
RKTPVSRLSLFSFKQ	NR4A2	166	P43354
IIEPLTSRCSKFRFK	RFC4	186	P35249
KLSATRRSNKKLPFN	SH3D19	351	Q5HYK7
SARQSASFILVKRKP	TBC1D21	11	Q8IYX1
VRIKTSIFSLFRAPK	SLC22A24	331	Q8N4F4
SFTFKLKPSDKDRRL	PRKCA	226	P17252
RSAFPKAAIKRLIQS	TAF11	126	Q15544
RTQTPRAELKEKFTA	PTGDS	151	P41222
LTASPQKKRRFEFFD	SMARCAL1	931	Q9NZC9
KVFPNKRSFILTRST	SI	576	P14410
RFRVVKLDSSSEPFK	TSC22D1	406	Q15714
RKQARFPSTFSILKE	SLC25A53	146	Q5H9E4
RSPKLQSSKKVAFLR	NOP2	701	P46087
ENSTAKPFKRTEIRL	PROB1	721	E7EW31
TILRIPSASQRKKAF	OR6C3	221	Q9NZP0
SKSVKPRLASFRSLR	TRIP10	366	Q15642
FSPSLSRIDLKNKKR	CILK1	426	Q9UPZ9
RFTLKLRSLQKGTFD	RPF1	311	Q9H9Y2
KIPKNRTRTVNLTDF	THEMIS	191	Q8N1K5
QSTLFKDSPLRTLKR	SUN2	31	Q9UH99
TSLPLFRSKQFAVKR	SNX1	171	Q13596
AVFEAKFKRSRESPL	SPEG	2331	Q15772
ARRFLPEQFSKKSPQ	SLC9A2	711	Q9UBY0
AKPQLSTAKSRTRLF	TRPV1	36	Q8NER1
RSKQNLVPFRDSKLT	KIF20A	451	O95235
KRFLTNFPFSTAVKL	PRSS35	136	Q8N3Z0
SFVKKRKLRVSQEPF	ZNF587	156	Q96SQ5
LKSFFTEKRPISRAV	TMED3	201	Q9Y3Q3
SFVKKRKLRVSQEPF	ZNF417	156	Q8TAU3
DLLFFPQRDSKKSQR	TTC41P	996	Q6P2S7
NSIINTPLKRRKVFS	SENP6	411	Q9GZR1
LPRNTLSRSAFKFKK	TENM3	286	Q9P273
KDSIRTLRLFPFSSK	ZNF518A	1321	Q6AHZ1
RASPSKARLKEFLQQ	ZNF839	346	A8K0R7
FLRTPEQCRTKFKSL	ZKSCAN2	386	Q63HK3
TDRRFLPNKSKVFVA	WSCD1	341	Q658N2
NSKRRRFSSKPVVLT	USP44	541	Q9H0E7
QRVSFLKPLTRSKRD	ELFN2	726	Q5R3F8
KRKFLFNSDLREPAS	VLDLR	546	P98155
RVLSKAFSRLKTSLP	MSC	121	O60682