Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetylglucosamine-6-sulfatase activity	SULF2 SULF1	3.22e-05	3	66	2	GO:0008449
GeneOntologyBiologicalProcess	glomerular basement membrane development	SULF2 SULF1 WT1	3.53e-06	10	65	3	GO:0032836
GeneOntologyBiologicalProcess	negative regulation of keratinocyte apoptotic process	SERPINB13 TRIM32	9.78e-06	2	65	2	GO:1902173
GeneOntologyBiologicalProcess	esophagus smooth muscle contraction	SULF2 SULF1	9.78e-06	2	65	2	GO:0014846
Domain	Extracellular_sulfatase	SULF2 SULF1	1.19e-05	2	65	2	IPR014615
Domain	Extracellular_sulfatase_C	SULF2 SULF1	1.19e-05	2	65	2	IPR024609
Domain	DUF3740	SULF2 SULF1	1.19e-05	2	65	2	PF12548
Domain	Serpin_B9/Maspin	SERPINB9 SERPINB13	7.12e-05	4	65	2	IPR000240
Domain	Guanine_nucleotide-bd_bsu	GNB1 GNB3	1.18e-04	5	65	2	IPR016346
Domain	Peptidase_M13	ECEL1 MME	2.48e-04	7	65	2	PF01431
Domain	Peptidase_M13_C	ECEL1 MME	2.48e-04	7	65	2	IPR018497
Domain	Peptidase_M13	ECEL1 MME	2.48e-04	7	65	2	IPR000718
Domain	Peptidase_M13_N	ECEL1 MME	2.48e-04	7	65	2	PF05649
Domain	Peptidase_M13_N	ECEL1 MME	2.48e-04	7	65	2	IPR008753
Domain	Gprotein_B	GNB1 GNB3	5.27e-04	10	65	2	IPR001632
Domain	MKP	DUSP1 DUSP6	5.27e-04	10	65	2	IPR008343
Domain	Sulfatase_CS	SULF2 SULF1	1.39e-03	16	65	2	IPR024607
Domain	SULFATASE_1	SULF2 SULF1	1.57e-03	17	65	2	PS00523
Domain	SULFATASE_2	SULF2 SULF1	1.57e-03	17	65	2	PS00149
Domain	Sulfatase	SULF2 SULF1	1.76e-03	18	65	2	PF00884
Domain	Sulfatase_N	SULF2 SULF1	1.76e-03	18	65	2	IPR000917
Domain	RHOD	DUSP1 DUSP6	2.63e-03	22	65	2	SM00450
Domain	RHODANESE_3	DUSP1 DUSP6	2.88e-03	23	65	2	PS50206
Domain	Rhodanese-like_dom	DUSP1 DUSP6	3.13e-03	24	65	2	IPR001763
Domain	Rhodanese	DUSP1 DUSP6	3.13e-03	24	65	2	PF00581
Domain	-	DUSP1 DUSP6	3.13e-03	24	65	2	3.40.250.10
Domain	G-protein_beta_WD-40_rep	FBXW9 GNB1 GNB3	3.24e-03	85	65	3	IPR020472
Domain	Prot-tyrosine_phosphatase-like	DUSP1 SBF2 DUSP6	4.97e-03	99	65	3	IPR029021
Domain	DUSP	DUSP1 DUSP6	5.20e-03	31	65	2	IPR024950
Domain	Alkaline_phosphatase_core	SULF2 SULF1	5.20e-03	31	65	2	IPR017850
Domain	Alkaline_Pase-like_a/b/a	SULF2 SULF1	5.20e-03	31	65	2	IPR017849
Domain	-	SULF2 SULF1	5.20e-03	31	65	2	3.40.720.10
Domain	Serpin_CS	SERPINB9 SERPINB13	5.53e-03	32	65	2	IPR023795
Domain	TYR_PHOSPHATASE_DUAL	DUSP1 DUSP6	6.23e-03	34	65	2	PS50054
Domain	TYR_PHOSPHATASE_DUAL_dom	DUSP1 DUSP6	6.59e-03	35	65	2	IPR020422
Domain	DSPc	DUSP1 DUSP6	6.59e-03	35	65	2	SM00195
Domain	Serpin_dom	SERPINB9 SERPINB13	6.96e-03	36	65	2	IPR023796
Domain	SERPIN	SERPINB9 SERPINB13	7.34e-03	37	65	2	SM00093
Domain	SERPIN	SERPINB9 SERPINB13	7.34e-03	37	65	2	PS00284
Pathway	REACTOME_PEPTIDE_HORMONE_METABOLISM	PLA2G7 MME GNB1 GNB3	1.36e-04	70	53	4	MM14916
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	KCNJ16 GNB1 GNB3	1.90e-04	30	53	3	MM14542
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	SCNN1A GNB1 GNB3	2.09e-04	31	53	3	MM15691
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ16 GNB1 GNB3	3.02e-04	35	53	3	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ16 GNB1 GNB3	3.28e-04	36	53	3	MM14544
Pathway	REACTOME_PEPTIDE_HORMONE_METABOLISM	PLA2G7 MME GNB1 GNB3	3.29e-04	88	53	4	M27211
Pathway	BIOCARTA_DSP_PATHWAY	DUSP1 DUSP6	4.91e-04	9	53	2	M22032
Pathway	BIOCARTA_DSP_PATHWAY	DUSP1 DUSP6	4.91e-04	9	53	2	MM1554
Pathway	REACTOME_PROTEIN_FOLDING	FBXW9 GNB1 GNB3 TUBAL3	4.95e-04	98	53	4	M776
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ16 GNB1 GNB3	5.57e-04	43	53	3	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ16 GNB1 GNB3	5.96e-04	44	53	3	MM15709
Pathway	REACTOME_ASPIRIN_ADME	ACSM4 UGT1A8 ALB	5.96e-04	44	53	3	M45014
Pathway	REACTOME_ASPIRIN_ADME	ACSM4 UGT1A8 ALB	6.37e-04	45	53	3	MM15694
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	SCNN1A GNB1 GNB3	7.24e-04	47	53	3	M42524
Pubmed	WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.	SULF2 SULF1 WT1	6.83e-09	3	67	3	21719793
Pubmed	The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes.	NFE2L2 DUSP1	3.66e-06	2	67	2	30262569
Pubmed	Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.	SULF2 SULF1	3.66e-06	2	67	2	16901266
Pubmed	HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.	SULF2 SULF1	3.66e-06	2	67	2	16192265
Pubmed	Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.	SULF2 SULF1	3.66e-06	2	67	2	28657777
Pubmed	PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.	NFE2L2 PRKCI	3.66e-06	2	67	2	32589943
Pubmed	SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.	SULF2 SULF1	3.66e-06	2	67	2	24726914
Pubmed	Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.	SULF2 SULF1	3.66e-06	2	67	2	20394677
Pubmed	Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice.	NFE2L2 POU1F1	3.66e-06	2	67	2	19933842
Pubmed	SULFs in human neoplasia: implication as progression and prognosis factors.	SULF2 SULF1	3.66e-06	2	67	2	21599997
Pubmed	Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.	SULF2 SULF1	3.66e-06	2	67	2	27294358
Pubmed	Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.	SULF2 SULF1	3.66e-06	2	67	2	20479257
Pubmed	Amine oxidase copper-containing 1 (AOC1) is a downstream target gene of the Wilms tumor protein, WT1, during kidney development.	AOC1 WT1	3.66e-06	2	67	2	25037221
Pubmed	An actin-based wave generator organizes cell motility.	WASF1 NCKAP1L	3.66e-06	2	67	2	17696648
Pubmed	Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.	SULF2 SULF1	3.66e-06	2	67	2	26448642
Pubmed	Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.	SULF2 SULF1	3.66e-06	2	67	2	35131262
Pubmed	Interplay of MKP-1 and Nrf2 drives tumor growth and drug resistance in non-small cell lung cancer.	NFE2L2 DUSP1	3.66e-06	2	67	2	31811110
Pubmed	Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.	SULF2 SULF1	3.66e-06	2	67	2	34489650
Pubmed	Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.	SULF2 SULF1	3.66e-06	2	67	2	17920055
Pubmed	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.	SULF2 SULF1	3.66e-06	2	67	2	12368295
Pubmed	Overexpression of Sulf2 in idiopathic pulmonary fibrosis.	SULF2 SULF1	3.66e-06	2	67	2	23418199
Pubmed	Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.	SULF2 SULF1	3.66e-06	2	67	2	34324645
Pubmed	Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.	SULF2 SULF1	3.66e-06	2	67	2	18687675
Pubmed	Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.	SULF2 SULF1	3.66e-06	2	67	2	31461325
Pubmed	Functional consequences of the subdomain organization of the sulfs.	SULF2 SULF1	3.66e-06	2	67	2	19520866
Pubmed	The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.	SULF2 SULF1	3.66e-06	2	67	2	23950901
Pubmed	Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.	SULF2 SULF1	3.66e-06	2	67	2	23480519
Pubmed	Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.	SULF2 SULF1	3.66e-06	2	67	2	18507859
Pubmed	Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.	SULF2 SULF1	3.66e-06	2	67	2	26764203
Pubmed	SULF1/SULF2 reactivation during liver damage and tumour growth.	SULF2 SULF1	3.66e-06	2	67	2	27013228
Pubmed	Heparan Sulfate-Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair.	SULF2 SULF1	3.66e-06	2	67	2	31434553
Pubmed	Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.	SULF2 SULF1	3.66e-06	2	67	2	29360432
Pubmed	Chromosomal localization of the genes encoding two forms of the G protein beta polypeptide, beta 1 and beta 3, in man.	GNB1 GNB3	3.66e-06	2	67	2	1979057
Pubmed	Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.	SULF2 SULF1	3.66e-06	2	67	2	25477293
Pubmed	Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.	SULF2 SULF1	3.66e-06	2	67	2	22298771
Pubmed	DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma.	DPP9 NFE2L2	3.66e-06	2	67	2	37713596
Pubmed	Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2.	SULF2 SULF1	3.66e-06	2	67	2	32038163
Pubmed	WT1 induction of mitogen-activated protein kinase phosphatase 3 represents a novel mechanism of growth suppression.	DUSP6 WT1	3.66e-06	2	67	2	18644985
Pubmed	Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation.	NFE2L2 DUSP1	3.66e-06	2	67	2	30061089
Pubmed	A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131.	GNB1 GNB3 MUC2	4.56e-06	17	67	3	24367558
Pubmed	Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.	SULF2 SULF1	1.10e-05	3	67	2	17116694
Pubmed	Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.	SULF2 SULF1	1.10e-05	3	67	2	22865881
Pubmed	Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.	SULF2 SULF1	1.10e-05	3	67	2	29062064
Pubmed	Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.	SULF2 SULF1	1.10e-05	3	67	2	25448158
Pubmed	CD40-modulated dual-specificity phosphatases MAPK phosphatase (MKP)-1 and MKP-3 reciprocally regulate Leishmania major infection.	DUSP1 DUSP6	1.10e-05	3	67	2	21471446
Pubmed	Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.	SULF2 SULF1	1.10e-05	3	67	2	25370455
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB3	1.10e-05	3	67	2	11913780
Pubmed	Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene.	WT1 ALB	2.19e-05	4	67	2	16467207
Pubmed	Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap.	NFE2L2 ALB	2.19e-05	4	67	2	30470740
Pubmed	Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.	SULF2 SULF1	2.19e-05	4	67	2	23074159
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB1 GNB3	2.19e-05	4	67	2	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB1 GNB3	2.19e-05	4	67	2	12512701
Pubmed	HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity.	SULF2 SULF1	2.19e-05	4	67	2	23457216
Pubmed	Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome.	KCNJ16 SCNN1A	2.19e-05	4	67	2	25339316
Pubmed	Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.	SULF2 SULF1	2.19e-05	4	67	2	20855470
Pubmed	Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.	SULF2 SULF1	2.19e-05	4	67	2	17593974
Pubmed	Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia.	GNB1 GNB3	2.19e-05	4	67	2	25093805
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB3	2.19e-05	4	67	2	19255495
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF821 TRIM32 NFE2L2 SULF1 MICAL2 LRRN2 KDM4A ATM ZNF302 MED13L GNB1	3.23e-05	1285	67	11	35914814
Pubmed	Intersubunit surfaces in G protein alpha beta gamma heterotrimers. Analysis by cross-linking and mutagenesis of beta gamma.	GNB1 GNB3	3.64e-05	5	67	2	8550614
Pubmed	Localization of the gene for a third G protein beta-subunit to mouse chromosome 6 near Raf-1.	GNB1 GNB3	3.64e-05	5	67	2	1572642
Pubmed	Roles of heparan sulfate sulfation in dentinogenesis.	SULF2 SULF1	3.64e-05	5	67	2	22351753
Pubmed	Nrf2 Transcriptional Activity Governs Intestine Development.	NFE2L2 MUC2	3.64e-05	5	67	2	35682851
Pubmed	Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.	SULF2 SULF1	3.64e-05	5	67	2	20643830
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MME MUC2	3.64e-05	5	67	2	22261707
Pubmed	ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress.	TRIM32 ATM	3.64e-05	5	67	2	37943659
Pubmed	ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.	DUSP1 DUSP6	5.46e-05	6	67	2	17131384
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB1 GNB3	5.46e-05	6	67	2	16884933
Pubmed	Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation.	NFE2L2 ATM	7.63e-05	7	67	2	28930658
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB1 GNB3	7.63e-05	7	67	2	10570481
Pubmed	Anthracyclines induce DNA damage response-mediated protection against severe sepsis.	NFE2L2 ATM	7.63e-05	7	67	2	24184056
Pubmed	Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development.	SULF2 SULF1	7.63e-05	7	67	2	18213582
Pubmed	Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.	SULF2 SULF1	7.63e-05	7	67	2	20410206
Pubmed	Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration.	WT1 ALB	7.63e-05	7	67	2	22298767
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	PLA2G7 NFE2L2 SCNN1A MME GNB3	8.21e-05	229	67	5	19948975
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB3	1.02e-04	8	67	2	9789084
Pubmed	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.	HECW1 SCNN1A	1.02e-04	8	67	2	11244092
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB3	1.02e-04	8	67	2	24462769
Pubmed	ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia.	ATM NCKAP1L	1.02e-04	8	67	2	17875758
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB1 GNB3	1.02e-04	8	67	2	2328987
Pubmed	RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.	NFE2L2 ALB	1.02e-04	8	67	2	34921137
Pubmed	A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.	DUSP1 DUSP6	1.02e-04	8	67	2	11359773
Pubmed	SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.	SULF2 SULF1	1.30e-04	9	67	2	17720696
Pubmed	HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers.	NFE2L2 ALB	1.30e-04	9	67	2	29558368
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB1 GNB3	1.30e-04	9	67	2	10339615
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB1 GNB3	1.63e-04	10	67	2	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB1 GNB3	1.63e-04	10	67	2	9733924
Pubmed	Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding.	ACSM4 OR5B21	1.99e-04	11	67	2	26361056
Pubmed	The G protein subunit gene families.	GNB1 GNB3	1.99e-04	11	67	2	10644457
Pubmed	Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study.	SCNN1A GNB3	1.99e-04	11	67	2	20577119
Pubmed	GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice.	WT1 ALB	1.99e-04	11	67	2	24415412
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB1 GNB3	1.99e-04	11	67	2	25982117
Pubmed	Expression profile of protein kinase C isozymes in preimplantation mouse development.	LRRN2 PRKCI	1.99e-04	11	67	2	16183862
Pubmed	Dysregulated cell signalling and reduced satellite cell potential in ageing muscle.	SULF2 SULF1	2.38e-04	12	67	2	31647919
Pubmed	Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.	SULF2 SULF1	2.38e-04	12	67	2	28490013
Pubmed	Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways.	DUSP1 DUSP6	2.38e-04	12	67	2	25951516
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB1 GNB3	2.38e-04	12	67	2	20186915
Pubmed	HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?	PRKCI ATM	2.38e-04	12	67	2	18577246
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB1 GNB3	2.38e-04	12	67	2	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB1 GNB3	2.38e-04	12	67	2	8636150
GeneFamily	MAP kinase phosphatases	DUSP1 DUSP6	4.22e-04	11	51	2	895
GeneFamily	Sulfatases	SULF2 SULF1	1.16e-03	18	51	2	410
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE	SULF2 SERPINB9 GAS2L3 PLEKHM2 NFE2L2 MICAL2 SBF2 DUSP6 EVI2B MME MED13L WASF1 SH2B2 NCKAP1L	1.82e-06	1250	65	14	M41099
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	PLA2G7 SERPINB9 PLEKHM2 TRIM32 NFE2L2 SULF1 MICAL2 SCNN1A WT1 GNB1 GNB3 WASF1 NCKAP1L	9.39e-06	1242	65	13	M1920
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	PLA2G7 SERPINB9 PLEKHM2 TRIM32 NFE2L2 SULF1 MICAL2 SCNN1A WT1 GNB1 GNB3 WASF1 NCKAP1L	1.74e-05	1316	65	13	MM1052
Coexpression	LIM_MAMMARY_STEM_CELL_UP	PLA2G7 SCML2 ARHGEF28 SULF1 MICAL2 TRPC1 DUSP6 MME	2.38e-05	479	65	8	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	PLA2G7 SCML2 ARHGEF28 SULF1 MICAL2 TRPC1 DUSP6 MME	2.52e-05	483	65	8	MM1082
CoexpressionAtlas	BM Top 100 - kidney cortex	AOC1 KCNJ16 SCNN1A ALB MME	4.39e-06	83	62	5	BM Top 100 - kidney cortex
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1	PLA2G7 SULF2 GPR35 DUSP1 KCNJ16 EVI2B SH2B2 ADGRL3	1.48e-05	382	62	8	GSM538248_500
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	5.21e-05	25	62	3	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	SULF2 SULF1 MICAL2 MME ADGRL3	8.45e-05	153	62	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100	SULF1 WT1 MME ADGRL3	9.72e-05	82	62	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	1.01e-04	31	62	3	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k3_200
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2	PLA2G7 SULF2 GPR35 DUSP1 EVI2B SH2B2 ADGRL3	1.10e-04	376	62	7	GSM538266_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_100	SULF1 WT1 ADGRL3	1.11e-04	32	62	3	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_100
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3	PLA2G7 SULF2 GPR35 DUSP1 KCNJ16 EVI2B ADGRL3	1.40e-04	391	62	7	GSM538249_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	SULF2 GPR35 DUSP1 KCNJ16 EVI2B SH2B2 ADGRL3	1.49e-04	395	62	7	GSM538265_500
CoexpressionAtlas	Myeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2	PLA2G7 SULF2 MTUS1 GPR35 DUSP1 DUSP6 SH2B2	1.66e-04	402	62	7	GSM854320_500
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	SULF2 SULF1 DUSP1 TRPC1 DUSP6 WT1 MME MED13L WASF1 ADGRL3	1.76e-04	858	62	10	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	PLA2G7 SULF2 GAS2L3 GPR35 DUSP1 SBF2 ADGRL3	1.79e-04	407	62	7	GSM538245_500
CoexpressionAtlas	Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4	PLA2G7 SULF2 MTUS1 GPR35 DUSP1 DUSP6 EVI2B	1.82e-04	408	62	7	GSM605868_500
CoexpressionAtlas	Myeloid Cells, DC.103+11b-.Lv, CD45+ CD11c+ MHC-II+ CD11b low CD103+, Liver, avg-2	PLA2G7 SULF2 GAS2L3 GPR35 DUSP1 EVI2B ALB	1.85e-04	409	62	7	GSM538234_500
CoexpressionAtlas	Myeloid Cells, GN.Arth.SynF, CD11b+ Ly6-G+, Synovial Fluid, avg-3	PLA2G7 MTUS1 GPR35 NFE2L2 DUSP1 DUSP6 SH2B2	2.11e-04	418	62	7	GSM854338_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200	SULF2 MICAL2 MME	2.51e-04	42	62	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500	SULF1 MICAL2 DUSP1 DUSP6 WT1 MME ADGRL3	2.58e-04	432	62	7	gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	2.88e-04	44	62	3	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_200
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	4.73e-04	52	62	3	gudmap_dev gonad_e11.5_F_GonMes_Sma_k3_200
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000	SULF2 SULF1 MICAL2 DUSP1 WT1 ALB MME WASF1 ADGRL3	4.82e-04	797	62	9	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	5.29e-04	54	62	3	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_200
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	5.58e-04	55	62	3	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_200
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	ZNF821 SULF2 SULF1 MICAL2 DUSP6 WT1 MME WASF1 ADGRL3	6.29e-04	827	62	9	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_200	SULF1 WT1 ADGRL3	6.52e-04	58	62	3	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	SULF2 SULF1 MICAL2 WT1 MME ADGRL3	6.67e-04	364	62	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_500	SULF1 WT1 ADGRL3	7.56e-04	61	62	3	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k3_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	SULF2 SULF1 MICAL2 DUSP1 DUSP6 WT1 MME WASF1 ADGRL3	7.58e-04	849	62	9	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	Myeloid Cells, DC.103+11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103+ F4/80-lo, Small Intestine, avg-4	PLA2G7 SULF2 SERPINB9 MICAL2 DUSP1 ADGRL3	7.79e-04	375	62	6	GSM854237_500
CoexpressionAtlas	BM Top 100 - substantia nigra	KCNJ16 SV2C EVI2B	8.31e-04	63	62	3	BM Top 100 - substantia nigra
CoexpressionAtlas	Myeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7	PLA2G7 SULF2 GAS2L3 DUSP1 DUSP6 ADGRL3	8.46e-04	381	62	6	GSM854262_500
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	PLA2G7 SULF2 GPR35 DUSP1 EVI2B ADGRL3	8.69e-04	383	62	6	GSM605826_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	SULF2 SULF1 MME ADGRL3	9.01e-04	147	62	4	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000	SULF1 WT1 MED13L WASF1 ADGRL3	9.54e-04	259	62	5	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000
CoexpressionAtlas	Myeloid Cells, MF.Medl.SLN, CD11b+ CD169+ F4/80+, Lymph Node, avg-2	PLA2G7 SULF2 MTUS1 GPR35 DUSP1 DUSP6	9.67e-04	391	62	6	GSM854322_500
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_100	SULF1 ADGRL3	9.80e-04	16	62	2	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_100
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100	SULF1 ADGRL3	9.80e-04	16	62	2	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k1_100
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200	SULF1 WT1 MME ADGRL3	1.02e-03	152	62	4	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200
CoexpressionAtlas	Myeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	PLA2G7 SULF2 GPR35 DUSP1 EVI2B ADGRL3	1.09e-03	400	62	6	GSM538242_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 ADGRL3	1.11e-03	17	62	2	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_200
CoexpressionAtlas	Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3	PLA2G7 MTUS1 GPR35 DUSP1 DUSP6 SCNN1A	1.12e-03	402	62	6	GSM605883_500
CoexpressionAtlas	Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3	PLA2G7 PLEKHM2 DUSP1 SBF2 KCNJ16 ADGRL3	1.13e-03	403	62	6	GSM605853_500
CoexpressionAtlas	BM Top 100 - dorsal root ganglia	GAS2L3 SV2C MME	1.18e-03	71	62	3	BM Top 100 - dorsal root ganglia
CoexpressionAtlas	Myeloid Cells, DC.8+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-2	SULF2 SERPINB9 DUSP1 EVI2B SH2B2 ADGRL3	1.19e-03	407	62	6	GSM538258_500
CoexpressionAtlas	Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3	PLA2G7 SULF2 MTUS1 DUSP1 DUSP6 EVI2B	1.25e-03	411	62	6	GSM605872_500
CoexpressionAtlas	Myeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3	PLA2G7 SULF2 MTUS1 GPR35 DUSP1 ALB	1.25e-03	411	62	6	GSM538239_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200	SULF1 WT1 MME ADGRL3	1.26e-03	161	62	4	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.Sp, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Spleen, avg-1	SULF2 GPR35 DUSP1 EVI2B SH2B2 ADGRL3	1.26e-03	412	62	6	GSM605839_500
CoexpressionAtlas	Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2	PLA2G7 SULF2 MTUS1 GPR35 DUSP1 DUSP6	1.28e-03	413	62	6	GSM605878_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200	SULF1 WT1 MME ADGRL3	1.29e-03	162	62	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
CoexpressionAtlas	BM Top 100 - kidney medulla	AOC1 KCNJ16 SCNN1A	1.33e-03	74	62	3	BM Top 100 - kidney medulla
CoexpressionAtlas	Myeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3	PLA2G7 MTUS1 NFE2L2 DUSP1 DUSP6 SH2B2	1.33e-03	416	62	6	GSM854309_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	SULF1 MICAL2 DUSP6 WT1 MME ADGRL3	1.36e-03	418	62	6	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	BM Top 100 - trigeminal ganglia	GAS2L3 SV2C MME	1.38e-03	75	62	3	BM Top 100 - trigeminal ganglia
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	PLA2G7 SULF2 ADGRL3	1.38e-03	75	62	3	GSM605826_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_200	SULF1 ADGRL3	1.39e-03	19	62	2	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_200
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_100	SULF1 ADGRL3	1.39e-03	19	62	2	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_100
CoexpressionAtlas	BM Top 100 - prostate gland	AOC1 SCNN1A MME	1.43e-03	76	62	3	BM Top 100 - prostate gland
CoexpressionAtlas	Myeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	SULF2 SERPINB9 GPR35 DUSP1 SBF2 EVI2B	1.48e-03	425	62	6	GSM538255_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_100	SULF1 ADGRL3	1.54e-03	20	62	2	gudmap_dev gonad_e11.5_M_GonMes_Sma_k2_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	MICAL2 MME ADGRL3	1.54e-03	78	62	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GAS2L3 GPR35 EVI2B NCKAP1L	4.19e-06	164	65	5	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GAS2L3 GPR35 EVI2B NCKAP1L	4.19e-06	164	65	5	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	droplet-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SCML2 GPR35 DUSP1 SCNN1A	4.45e-06	166	65	5	e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCell	droplet-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SCML2 GPR35 DUSP1 SCNN1A	4.45e-06	166	65	5	3ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCell	control\|World / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PLA2G7 SULF2 MICAL2 DUSP1 MME	5.14e-06	171	65	5	837c1186504f110ccf5b580d9cd4e50ca60c173f
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	SERPINB13 MTUS1 NFE2L2 UGT1A8 PRKCI	5.14e-06	171	65	5	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	facs-Trachea-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GAS2L3 GPR35 EVI2B NCKAP1L	5.29e-06	172	65	5	c260680f5455fce133b7b4158b4197fc76115779
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MTUS1 MICAL2 ECEL1 MME	6.59e-06	180	65	5	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MTUS1 MICAL2 ECEL1 MME	6.96e-06	182	65	5	1e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MTUS1 ECEL1 MME SLC44A3	7.33e-06	184	65	5	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MTUS1 MICAL2 ECEL1 MME	7.33e-06	184	65	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MTUS1 ECEL1 MME SLC44A3	7.53e-06	185	65	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	P07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SERPINB9 ARHGEF28 SCNN1A TEKT5 SLC44A3	8.79e-06	191	65	5	0f360766490bef3495c42f6421b22a988cfc68fb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 KCNJ16 SCNN1A MME SLC44A3	9.24e-06	193	65	5	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFE2L2 DUSP6 KCNJ16 SCNN1A LRRN2	9.72e-06	195	65	5	3f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCell	3'-Child09-12\|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AOC1 DUSP1 EVI2B MME MUC2	9.96e-06	196	65	5	1bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF28 MTUS1 ECEL1 MME SLC44A3	1.02e-05	197	65	5	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF2 SERPINB9 AOC1 GPR35 TUBAL3	1.07e-05	199	65	5	6fc8c321e2ddd802b9c8edfe16e006c7d4d862fc
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLA2G7 SULF2 SERPINB9 GAS2L3 SH2B2	1.07e-05	199	65	5	51be0e3a91d1f25454b56d55ef6342ef8e8df4e8
ToppCell	LPS_IL1RA\|World / Treatment groups by lineage, cell group, cell type	SERPINB9 SLC39A14 MED13L SH2B2 ADGRL3	1.10e-05	200	65	5	a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 PLEKHM2 KCNJ16 ADGRL3	7.22e-05	152	65	4	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SCML2 FBXW9 SBF2 PRKCI	7.41e-05	153	65	4	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SCML2 FBXW9 SBF2 PRKCI	7.41e-05	153	65	4	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	7.79e-05	155	65	4	d2e489a08b4e711bd2ed483dcc4da7dbbaa4feea
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	7.79e-05	155	65	4	cb456d6f13bfb5cb400c0840a0ab6ba4616dcf37
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	7.79e-05	155	65	4	a547fdcd974b0813ce6c8cccfec9fff74cac2d1a
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SULF2 SERPINB9 SH2B2 NCKAP1L	7.79e-05	155	65	4	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 PLEKHM2 GPR35 KCNJ16	8.19e-05	157	65	4	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	droplet-Lung-nan-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 DUSP1 SCNN1A EVI2B	8.19e-05	157	65	4	3cffedafff31efb5b3259194157b54a768367459
ToppCell	droplet-Lung-nan-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 DUSP1 SCNN1A EVI2B	8.19e-05	157	65	4	f87e867a394b0453ebd92c592e80450caf5902cb
ToppCell	facs-Lung-EPCAM-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GAS2L3 GPR35 EVI2B	8.39e-05	158	65	4	ef5feb48161c339c7b71c576bdda61479d29dfac
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GAS2L3 GPR35 EVI2B	8.39e-05	158	65	4	c6e64b9b3342e37d54baadae8fb7dfb5d246e4cf
ToppCell	droplet-Lung-nan-21m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 DUSP1 SCNN1A EVI2B	8.60e-05	159	65	4	555ebf719504980c7584203a3ee1ba5779ab76d8
ToppCell	droplet-Lung-nan-21m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 DUSP1 SCNN1A EVI2B	8.60e-05	159	65	4	a6a5cded6da02a112e04c2c71ce08cc27c1c5002
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 PLEKHM2 KCNJ16 NCKAP1L	9.46e-05	163	65	4	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 PLEKHM2 KCNJ16 NCKAP1L	9.46e-05	163	65	4	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 SH2B2 NCKAP1L	9.69e-05	164	65	4	8d089844896e84935eab705ebe54f125c4b6d9ca
ToppCell	5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UGT1A8 WT1 ECEL1 MUC2	9.69e-05	164	65	4	29da0175bd3808a5b3039a6161c764105608ef96
ToppCell	5'-Adult-Appendix-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UGT1A8 WT1 ECEL1 MUC2	9.69e-05	164	65	4	e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCell	droplet-Fat-Mat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 NFE2L2 SCNN1A EVI2B	9.69e-05	164	65	4	a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCell	facs-MAT-Fat-3m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 GPR35 EVI2B NCKAP1L	9.69e-05	164	65	4	b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 SH2B2 NCKAP1L	9.69e-05	164	65	4	17fb1421476ba44999b1165f2576514f74c1f882
ToppCell	droplet-Heart-4Chambers-18m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 SCNN1A EVI2B SH2B2	9.92e-05	165	65	4	a761e0a36d5da8fec916d684f81e60f5590fd9ee
ToppCell	droplet-Limb_Muscle-nan-24m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	9.92e-05	165	65	4	8a3cfec76cc7c5a309d582becd1aef4261b7f4e1
ToppCell	droplet-Heart-4Chambers-18m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 SCNN1A EVI2B SH2B2	9.92e-05	165	65	4	680bdd150bc0a4e50244e57b1226a9b06a6bdbc9
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SULF2 GPR35 DUSP1	9.92e-05	165	65	4	11227bff52eed30b80937fdb1968d0b8e6d30365
ToppCell	droplet-Heart-4Chambers-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 SCNN1A EVI2B SH2B2	9.92e-05	165	65	4	af423307af484661284793a08091777d998e6fba
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SULF2 GPR35 DUSP1	9.92e-05	165	65	4	036f9749048e5e50769cc3210339bf4da469215d
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.02e-04	166	65	4	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-Lung-3m-Hematologic-myeloid\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GPR35 EVI2B NCKAP1L	1.02e-04	166	65	4	7bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCell	droplet-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 DUSP1 SCNN1A	1.02e-04	166	65	4	f751cbd01d4978ded7755874ab60504f6291afd7
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.02e-04	166	65	4	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 SH2B2 NCKAP1L	1.04e-04	167	65	4	7f9eedf68a800159c5642e04dd9569ae58109bd5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SULF2 SULF1 WT1 MME	1.06e-04	168	65	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	droplet-Fat-Scat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.06e-04	168	65	4	02dfe8037e61f9d4ac5f8df3929673bc212fd2cd
ToppCell	droplet-Fat-Scat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.06e-04	168	65	4	94916feefd413c84bb7d3fd2d3e403036b705b69
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SULF2 SULF1 WT1 MME	1.06e-04	168	65	4	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SULF2 SULF1 WT1 MME	1.06e-04	168	65	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 KCNJ16 WT1 SLC39A14	1.06e-04	168	65	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 DUSP1 SCNN1A	1.09e-04	169	65	4	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 DUSP1 SCNN1A	1.09e-04	169	65	4	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	facs-Trachea-nan-24m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GAS2L3 GPR35 NCKAP1L	1.09e-04	169	65	4	87e95804b3b19c245cea6293d72b64351293b0e8
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR35 TRPC1 ADGRL3 ADAMTSL2	1.11e-04	170	65	4	a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR35 TRPC1 ADGRL3 ADAMTSL2	1.11e-04	170	65	4	b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor-MUC5AC+ASCL1+_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SCNN1A TEKT5 SLC44A3 KLB	1.11e-04	170	65	4	d6e244725b21592c6056b9c443aac090f1eae836
ToppCell	facs-Trachea-nan-18m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.11e-04	170	65	4	774b0c1b453e19651f9481dc6bcabac538c5acb7
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GAS2L3 SH2B2 NCKAP1L	1.14e-04	171	65	4	26755e43d94e934106fc19ab929e4d34c17d6cba
ToppCell	facs-GAT-Fat-3m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.14e-04	171	65	4	3f796d53d3110e5d6e97de53bb49d323944659d6
ToppCell	facs-GAT-Fat-3m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.14e-04	171	65	4	d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCell	facs-GAT-Fat-3m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.14e-04	171	65	4	e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCell	facs-Lung-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GPR35 EVI2B NCKAP1L	1.14e-04	171	65	4	4ad28ecfde3d529a09b80be908c446bd5274518e
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GPR35 DUSP1 SCNN1A	1.14e-04	171	65	4	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	facs-Trachea-nan-18m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.14e-04	171	65	4	9d496a6edac9663791cda684188d49895246f6fe
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 GPR35 EVI2B NCKAP1L	1.16e-04	172	65	4	cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 HECW1 DUSP1 SCNN1A	1.16e-04	172	65	4	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GPR35 DUSP1 SCNN1A	1.16e-04	172	65	4	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 HECW1 DUSP1 SCNN1A	1.16e-04	172	65	4	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	droplet-Liver-Npc-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PLEKHM2 KCNJ16 SV2C	1.19e-04	173	65	4	9ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell	facs-Lung-EPCAM-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 GPR35 EVI2B NCKAP1L	1.19e-04	173	65	4	50b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCell	droplet-Thymus-nan-3m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 MTUS1 GPR35 SH2B2	1.19e-04	173	65	4	63f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell	facs-Trachea-24m-Hematologic-myeloid\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 GAS2L3 GPR35 NCKAP1L	1.22e-04	174	65	4	2f25fba5225f4687df4396645e94565a640b5583
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SULF1 DUSP1 DUSP6 WASF1	1.24e-04	175	65	4	6374ab186d7ccf7f6dfb858267edba8962789e15
ToppCell	droplet-Liver-Npc-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PLEKHM2 KCNJ16 EVI2B	1.24e-04	175	65	4	92a4a3fd323ee8360edd659f9e16dfddc8788e2f
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SULF2 SULF1 WT1 ECEL1	1.27e-04	176	65	4	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SULF2 SULF1 WT1 ECEL1	1.27e-04	176	65	4	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF2 GPR35 EVI2B NCKAP1L	1.27e-04	176	65	4	a85ad8b4815fde72edd5c900e882a0bc04033ea8
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PLEKHM2 KCNJ16 EVI2B	1.27e-04	176	65	4	8e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 MTUS1 SCNN1A SLC44A3	1.30e-04	177	65	4	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	NS-moderate-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SERPINB9 EVI2B WASF1 NCKAP1L	1.30e-04	177	65	4	de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 MTUS1 SCNN1A SLC44A3	1.30e-04	177	65	4	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SERPINB9 ARHGEF28 SCNN1A SLC44A3	1.33e-04	178	65	4	a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SERPINB9 ARHGEF28 SCNN1A SLC44A3	1.33e-04	178	65	4	b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell	facs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 SULF1 LRRN2 WASF1	1.39e-04	180	65	4	c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell	facs-Marrow-B-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 SULF1 LRRN2 WASF1	1.39e-04	180	65	4	07ac979b21be2425294d9818c48b5a1e6f014c19
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 HECW1 KCNJ16 MME	1.42e-04	181	65	4	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WT1 LRRN2 SUFU SLC44A3	1.45e-04	182	65	4	e3248d108b51c49ca2c978636e13017e23b53860
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTUS1 ECEL1 MME SLC44A3	1.45e-04	182	65	4	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HECW1 SV2C CAMK2N2 ECEL1	1.45e-04	182	65	4	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	severe-Myeloid-Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SULF2 DUSP1 EVI2B MME	1.48e-04	183	65	4	60a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SULF2 SULF1 WT1 MME	1.48e-04	183	65	4	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
Drug	Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; PC3; HT_HG-U133A	SULF1 MICAL2 DUSP1 POU1F1 EVI2B MUC2 ADGRL3	1.71e-06	195	67	7	4232_UP
Drug	Ro 31	PLA2G7 NFE2L2 DUSP1 TRPC1 DUSP6 PRKCI	3.71e-06	141	67	6	CID000214797
Disease	pre-malignant neoplasm (biomarker_via_orthology)	ATM SUFU MUC2	6.48e-06	17	64	3	DOID:0060071 (biomarker_via_orthology)
Disease	ovarian carcinoma (is_marker_for)	MTUS1 DUSP1 PRKCI	3.07e-05	28	64	3	DOID:4001 (is_marker_for)
Disease	lung adenocarcinoma	MTUS1 MICAL2 SBF2 ATM TEKT5	3.87e-05	174	64	5	EFO_0000571
Disease	Depressive disorder	DUSP1 DUSP6 PRKCI ALB GNB1 GNB3	3.90e-05	289	64	6	C0011581
Disease	Premature Ovarian Failure 1	NFE2L2 WT1	6.91e-05	6	64	2	C4552079
Disease	Gonadotropin-Resistant Ovary Syndrome	NFE2L2 WT1	6.91e-05	6	64	2	C0086367
Disease	Hypergonadotropic Ovarian Failure, X-Linked	NFE2L2 WT1	6.91e-05	6	64	2	C3494522
Disease	Hepatic Insufficiency	NFE2L2 ALB	1.65e-04	9	64	2	C1306571
Disease	Medulloblastoma	SCML2 ATM SUFU	1.77e-04	50	64	3	C0025149
Disease	Hepatomegaly	NFE2L2 ALB ADAMTSL2	2.23e-04	54	64	3	C0019209
Disease	pulmonary emphysema (is_marker_for)	NFE2L2 ALB	4.14e-04	14	64	2	DOID:9675 (is_marker_for)
Disease	Inborn Errors of Metabolism	PLA2G7 ADAMTSL2	6.17e-04	17	64	2	C0025521
Disease	breast cancer (is_marker_for)	DUSP1 DUSP6 WT1 KDM4A	7.09e-04	185	64	4	DOID:1612 (is_marker_for)
Disease	Hypertensive disease	AOC1 SCNN1A ALB GNB3	7.83e-04	190	64	4	C0020538
Disease	Lung Injury	ALB MME	9.47e-04	21	64	2	C0273115
Disease	Chronic Lung Injury	ALB MME	9.47e-04	21	64	2	C2350344
Disease	Ovarian Failure, Premature	NFE2L2 WT1	9.47e-04	21	64	2	C0085215
Disease	FEV/FEC ratio	ARHGEF28 MTUS1 SULF1 SBF2 LRRN2 ZNF319 SUFU TEKT5 HMGB1P1	1.28e-03	1228	64	9	EFO_0004713
Disease	hearing threshold measurement	SV2C LRRN2	1.69e-03	28	64	2	EFO_0007618
Disease	D dimer measurement	ARHGEF28 CSTPP1	1.94e-03	30	64	2	EFO_0004507
Disease	Ventricular Dysfunction, Left	NFE2L2 ATM	1.94e-03	30	64	2	C0242698
Disease	response to dolutegravir	RAB28 UGT1A8	1.94e-03	30	64	2	EFO_0600017
Disease	Bright Disease	WT1 ALB	2.07e-03	31	64	2	C1704377
Disease	Glomerulonephritis	WT1 ALB	2.07e-03	31	64	2	C0017658

Protein segments in the cluster

Peptide	Gene	Start	Entry
FNAETFTFHADICTL	ALB	526	P02768
FCFFRGLQSDRNTIH	ADGRL3	886	Q9HAR2
SFQELFQFASEEHSC	ACSM4	201	P0C7M7
FLNTTGFSFQDCHDR	AOC1	166	P19801
GFSFQDCHDRCLAFT	AOC1	171	P19801
RFCQENGFSSHFVSA	RAB28	146	P51157
SESLCHENSFFINEA	ARHGEF28	1556	Q8N1W1
GCFQLIRSFDVGHSF	FBXW9	376	Q5XUX1
TFRLSFCGSNEINHF	OR5B21	161	A6NL26
VGLHSCFQTESRLFF	PRKCI	316	P41743
AFTFFLHGESNVCTS	MED13L	166	Q71F56
ALQEFFCLSHDESNS	MTUS1	306	Q9ULD2
FHSASFQRLSDACRA	SBF2	226	Q86WG5
SCYNGNRFASHTRFS	HECW1	706	Q76N89
SQNSFSDARDCDFHA	LRRN2	101	O75325
SADHQAAEQFCAFFR	JRK	156	O75564
GLCTSRHLQNFFFIF	OR4K14	16	Q8NGD5
LCGNFDHRSNNDFTT	MUC2	991	Q02817
NCSPHFLNAFEDSFS	NFE2L2	241	Q16236
FCGHLNNTFFSKTET	EVI2B	11	P34910
GTLQNSAEFSEAFHC	MME	721	P08473
QCHFDINLNFDFTRS	NCKAP1L	116	P55160
HGFNCAESTNFATRR	KDM4A	281	O75164
HFASQEFFSANAISD	ADAMTSL2	446	Q86TH1
TFTGHESDINAICFF	GNB3	221	P16520
SSACFAQEFFIHGFS	OR51A2	96	Q8NGJ7
IQEGGFCFRSTRHNF	GPR35	156	Q9HC97
GSVSQFEEFGRAFHC	ECEL1	746	O95672
IRGSVHQNFADFTFA	PLA2G7	346	Q13093
FSLSFCGSNEIRHVF	OR5T1	176	Q8NG75
VQGFFTSCLRHFSQT	ATM	1866	Q13315
FNSVCQGTHILFREF	CSTPP1	51	Q9H6J7
TFTGHESDINAICFF	GNB1	221	P62873
LLDCRSFFAFNAGHI	DUSP1	26	P28562
FLFQASNSLFHCRDG	DPP9	151	Q86TI2
SGSFFARDNTANFLH	GAS2L3	116	Q86XJ1
QSNFCRTAHGDFVLT	CENPJ	241	Q9HC77
GTVDFCALNHFTTRF	KLB	816	Q86Z14
NSSHFTSINCFGDFI	SLC44A3	521	Q8N4M1
FSKFQAEFSLHCETN	DUSP6	136	Q16828
RELFEFFCNNTTIHG	SCNN1A	56	P37088
CFSSGDLFTAHNFSE	SLC39A14	91	Q15043
QHFESFVFSRGCQLS	MICAL2	1941	O94851
DRLFTCHEDCQTSFF	PLEKHM2	896	Q8IWE5
SHFFSENEDFRCIAG	TRIM32	566	Q13049
SFFHNKTGCQITFDD	SV2C	561	Q496J9
HGSEFSQTTICRFEN	POU1F1	161	P28069
CHSSIVRAFERNDFF	SLC26A8	761	Q96RN1
HSDASVNFSEFSNKC	HMGB1P1	31	B2RPK0
CFNLRNTSDCISFFH	TEKT5	266	Q96M29
HTNASFDTFFCETRA	TUBAL3	51	A6NHL2
FSCRLQDTNSFFAGN	CAMK2N2	26	Q96S95
NDTFHSFIGTCFALF	TRPC1	581	P48995
GFLQCHIENFSTEFL	UHRF1BP1L	1276	A0JNW5
RCDSAFDNTPNFSRH	ZNF273	546	Q14593
HNRANSILFCGRFSS	SERPINB9	361	P50453
SASFALRFLENFCHS	SCML2	441	Q9UQR0
HNESNSILFFGRFSS	SERPINB13	376	Q9UIV8
CVDNVHSFTGAFLFS	KCNJ16	111	Q9NPI9
RYVFQSENTFCSGDH	SUFU	146	Q9UMX1
EQCLSAFTVHFSGQF	WT1	86	P19544
LSAQDHQTFFTCDTD	ST7L	186	Q8TDW4
DAGASFSRHFAANFL	SH2B2	56	O14492
RFFSSSEFVQHRCDP	ZNF319	466	Q9P2F9
AVCGARFTSHATFNS	ZNF821	181	O75541
FNEAHSFSFRVNSLQ	WASF1	56	Q92558
TVNETHNFLFCEFAT	SULF1	781	Q8IWU6
RTINETHNFLFCEFA	SULF2	761	Q8IWU5
THNFLFCEFATGFLE	SULF2	766	Q8IWU5
SSSNGFFNLFFSHCR	UGT1A8	111	Q9HAW9
NFGFSALFEHCSEVT	ZNF302	86	Q9NR11