Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessG protein-coupled dopamine receptor signaling pathway

ADCY5 GSK3B VPS35 GNA11 GNAQ

1.40e-05441455GO:0007212
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

TNC LAMA2 TNN

2.11e-04171463GO:0098637
GeneOntologyCellularComponentstriated muscle myosin thick filament

MYOM1 OBSCN

2.88e-0441462GO:0005863
GeneOntologyCellularComponenttenascin complex

TNC TNN

2.88e-0441462GO:0090733
GeneOntologyCellularComponentphotoreceptor cell cilium

MAP1B WDR19 PROM1 GNA11 GNAQ USH2A

4.39e-041391466GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

MAP1B WDR19 PROM1 GNA11 GNAQ USH2A

7.28e-041531466GO:0097731
GeneOntologyCellularComponentprotein complex involved in cell adhesion

TNC LAMA2 ITGA3 TNN

7.71e-04591464GO:0098636
GeneOntologyCellularComponentnuclear speck

SART3 SRSF1 ASCC1 SYF2 IFI16 TCERG1 FIBP TAB1 MOCS2 DYRK3

9.18e-0443114610GO:0016607
GeneOntologyCellularComponentmembrane attack complex

C5 C7

9.94e-0471462GO:0005579
GeneOntologyCellularComponenthippocampal mossy fiber

MAP1B TNN

9.94e-0471462GO:0097457
GeneOntologyCellularComponentphotoreceptor outer segment

MAP1B WDR19 PROM1 GNA11 GNAQ

1.10e-031111465GO:0001750
GeneOntologyCellularComponentneuromuscular junction

ASCC1 LAMA2 ITGA3 LRP4 AKAP1

1.14e-031121465GO:0031594
GeneOntologyCellularComponentM band

MYOM1 MYOM3 OBSCN

1.30e-03311463GO:0031430
GeneOntologyCellularComponentmyofilament

MYOM1 OBSCN NEB

1.43e-03321463GO:0036379
Domainfn3

FNDC3B MYOM1 TNC MYOM3 OBSCN PTPRO TNN USH2A

4.12e-051621468PF00041
DomainFN3

FNDC3B MYOM1 TNC MYOM3 OBSCN PTPRO TNN USH2A

1.05e-041851468SM00060
DomainTUDOR

TDRD15 TDRD6 AKAP1

1.60e-04141463PF00567
DomainFN3

FNDC3B MYOM1 TNC MYOM3 OBSCN PTPRO TNN USH2A

1.73e-041991468PS50853
DomainMULTICOPPER_OXIDASE2

HEPH HEPHL1

1.81e-0431462PS00080
DomainFN3_dom

FNDC3B MYOM1 TNC MYOM3 OBSCN PTPRO TNN USH2A

2.42e-042091468IPR003961
DomainToprim

TOP2B TOP3A

3.60e-0441462PF01751
DomainCu-oxidase_2

HEPH HEPHL1

3.60e-0441462IPR011706
DomainGprotein_alpha_Q

GNA11 GNAQ

3.60e-0441462IPR000654
DomainToprim_domain

TOP2B TOP3A

3.60e-0441462IPR006171
DomainTOPRIM

TOP2B TOP3A

3.60e-0441462PS50880
DomainCu-oxidase_2

HEPH HEPHL1

3.60e-0441462PF07731
DomainSemaphorin

SEMA3C SEMA4G SEMA3D

4.84e-04201463IPR027231
DomainCu-oxidase_3

HEPH HEPHL1

5.98e-0451462IPR011707
DomainMULTICOPPER_OXIDASE1

HEPH HEPHL1

5.98e-0451462PS00079
DomainCu_oxidase_CS

HEPH HEPHL1

5.98e-0451462IPR033138
DomainCu-oxidase_3

HEPH HEPHL1

5.98e-0451462PF07732
DomainTUDOR

TDRD15 TDRD6 AKAP1

7.39e-04231463PS50304
Domain-

TDRD15 TDRD6

8.92e-04614622.40.50.90
DomainCLTH

RANBP10 GID8

8.92e-0461462PF10607
DomainCRA

RANBP10 GID8

8.92e-0461462SM00757
DomainCTLH/CRA

RANBP10 GID8

8.92e-0461462IPR024964
DomainStaphylococal_nuclease_OB-fold

TDRD15 TDRD6

8.92e-0461462IPR016071
DomainCu_oxidase_Cu_BS

HEPH HEPHL1

8.92e-0461462IPR002355
DomainCRA_dom

RANBP10 GID8

8.92e-0461462IPR013144
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SART3 RANBP10 EMC1 MAP1B ACADSB VPS45 PRDX4 HNRNPA3 ASCC1 TMEM43 IDH2 HUWE1 SSRP1 RRM1 IFI16 NOM1 VPS35 LRP4 MAIP1 GID8 STIP1 ATP5PD CNOT3 TOP2B HERC5

3.38e-0914401512530833792
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SART3 SMARCA5 SRSF1 POLA1 HNRNPA3 HUWE1 SSRP1 RRM1 GTF3C5 RPL23 TCERG1 VPS35 CSTF3 STIP1 VARS1 TOP2B

2.13e-086381511633239621
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SMARCA5 EMC1 SRSF1 MAP1B RBM45 RNPC3 PRDX4 HNRNPA3 TMEM43 IDH2 SSRP1 GTF3C5 RPL23 TCERG1 PTPRO CSTF3 MAP4K4 MTCH1 VARS1 TOP2B

5.38e-0810821512038697112
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

MAP1B RBL1 RPS6KA1 PRDX4 CDK11A NEB GSK3B AXIN1 RPL23 VPS35 FIBP SMS AKAP1

5.95e-084321511323455922
Pubmed

The protein interaction landscape of the human CMGC kinase group.

TFEB ZMYND11 SRSF1 RBL1 SNRNP35 CDK11A HUWE1 NEB GSK3B AXIN1 ADPRH FIBP STIP1 VARS1 CNOT3 DYRK3

6.88e-086951511623602568
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SART3 FNDC3B SEMA3C EMC1 FLYWCH1 VPS45 PRDX4 ASCC1 CDK11A SSRP1 CASZ1 TCERG1 NOM1 CDYL2 CSTF3 GNA11 STIP1 AKAP1 TACSTD2 ATP5PD VARS1 USP6NL CNOT3

1.41e-0714971512331527615
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SART3 SMARCA5 EMC1 SRSF1 POLA1 PRDX4 HNRNPA3 TMEM43 IDH2 HUWE1 SSRP1 GTF3C5 RPL23 TCERG1 VPS35 CSTF3 STIP1 ATIC TDRD6 MAP4K4 VARS1 TOP2B

2.50e-0714251512230948266
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SART3 RANBP10 EMC1 SRSF1 RPS6KA1 PRDX4 HNRNPA3 TMEM43 HUWE1 PTPRO VPS35 GID8 SMS STIP1 TAB1 GPSM1 ATP5PD VARS1

2.64e-079741511828675297
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

SRSF1 HNRNPA3 ASCC1 CDK11A SSRP1 IFI16 GTF3C5 NOM1 VPS35 MAIP1 MAP4K4 ATP5PD TOP2B HERC5

4.11e-076011511433658012
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TNIK SART3 SMARCA5 EMC1 MAP1B POLA1 IDH2 HUWE1 SSRP1 GTF3C5 RPL23 EIF4A2 MAIP1 SMS TOP2B

4.81e-077041511529955894
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

SART3 SMARCA5 SRSF1 MAP1B HUWE1 CASZ1 SEMA3D VPS35 GID8 TAF1 TOP2B

5.25e-073581511132460013
Pubmed

Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis.

GSK3B AXIN1 GID8

7.97e-075151328829046
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SART3 SMARCA5 EMC1 SRSF1 POLA1 KRT85 PRDX4 TBC1D7 HNRNPA3 HUWE1 SSRP1 RRM1 RPL23 TCERG1 VPS35 GID8 STIP1 ATP5PD VARS1 MOCS2 TOP2B

9.10e-0714151512128515276
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

SMARCA5 SRSF1 PRDX4 HNRNPA3 CDK11A IDH2 HUWE1 GSK3B RPL23 VPS35 STIP1 MAP4K4 VARS1 CNOT3

1.36e-066651511430457570
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

SART3 RANBP10 SMARCA5 SRSF1 MAP1B PRDX4 HNRNPA3 ASCC1 HUWE1 SSRP1 GTF3C5 GSK3B RPL23 PARP16 NOM1 VPS35 CSTF3 MAIP1 GID8 STIP1

1.47e-0613351512029229926
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SART3 FNDC3B SMARCA5 SRSF1 MAP1B POLA1 HNRNPA3 ADNP2 HUWE1 SSRP1 RRM1 IFI16 GTF3C5 GSK3B RPL23 TCERG1 VPS35 ATIC VARS1 TOP2B

1.80e-0613531512029467282
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MAP1B RBL1 RPS6KA1 PRDX4 TTC14 CDK11A TEC LYST GSK3B AXIN1 ANKRD36B YEATS4 FIBP TAB1 ATIC MAP4K4

2.42e-069101511636736316
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

SART3 MAP1B HEBP2 PRDX4 HNRNPA3 IDH2 HUWE1 SSRP1 DNAJB3 GTF3C5 RPL23 TCERG1 EIF4A2 VPS35 STIP1 TAB1 ATIC VARS1

2.78e-0611491511835446349
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TNIK TFEB SRSF1 SH3BP2 ASCC1 SSRP1 ZBTB1 CDC37L1 GTF3C5 GSK3B AXIN1 YEATS4 TAB1 TSTD2 GPSM1 MAP4K4 CNOT3

2.98e-0610381511726673895
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

SART3 SRSF1 RBM45 SNRNP35 HNRNPA3 ASCC1 ESRP2 ADAM5 AKAP1 TOP3A

3.10e-063471511016033648
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

RANBP10 SMARCA5 SRSF1 KBTBD8 SSRP1 RPL23 YEATS4 TCERG1 NOM1 TAF1 ATP5PD TOP2B

4.05e-065331511230554943
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

TNC BMP7 TNN

4.42e-068151323055981
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SART3 SMARCA5 FLYWCH1 MAP1B RBL1 CDK11A HUWE1 GTF3C5 CASZ1 ESRP2 YEATS4 TCERG1 VARS1 TOP2B HERC5

5.36e-068571511525609649
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FLYWCH1 OBSCN HUWE1 SEMA4G WDR19 ANKRD36B

5.47e-06101151610997877
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SART3 FNDC3B SEMA3C EMC1 MAP1B RBL1 RPS6KA1 ZZEF1 CEMIP TCERG1 NOM1 MAP4K4 TOP3A

5.72e-066501511338777146
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SART3 SMARCA5 SRSF1 SSRP1 CASZ1 CSTF3 STIP1 TOP2B

5.77e-06220151835785414
Pubmed

Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.

RANBP10 PRDX4 GTF3C5 GSK3B AXIN1 RPL23 GID8

7.05e-06161151736398662
Pubmed

Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein.

PRDX4 HNRNPA3 RRM1 EIF4A2 VPS35 CSTF3 ATP5PD

9.68e-06169151723665500
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK SART3 EMC1 MAP1B VPS45 TMEM43 IDH2 HUWE1 RPL23 GID8 STIP1 TAB1 MAP4K4 MTCH1 ATP5PD VARS1 CNOT3

1.01e-0511391511736417873
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SMARCA5 EMC1 SRSF1 MAP1B HNRNPA3 HUWE1 SSRP1 GTF3C5 RPL23 CSTF3 STIP1 ATIC MAP4K4 ATP5PD VARS1 TOP2B

1.06e-0510241511624711643
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

RANBP10 MAP1B TMEM43 HUWE1 ICMT GID8 TOP2B HERC5

1.59e-05253151829911972
Pubmed

The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.

GNA11 GNAQ

1.87e-052151228248732
Pubmed

Activation of Gq/11 in the mouse corpus luteum is required for parturition.

GNA11 GNAQ

1.87e-052151225495873
Pubmed

Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage.

LYST FCER1G

1.87e-052151216418262
Pubmed

Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons.

MAP1B GSK3B

1.87e-052151215731007
Pubmed

Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.

GNA11 GNAQ

1.87e-052151221945171
Pubmed

Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.

GNA11 GNAQ

1.87e-05215129175863
Pubmed

The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.

GNA11 GNAQ

1.87e-052151228083870
Pubmed

Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.

GNA11 GNAQ

1.87e-052151226843449
Pubmed

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.

GNA11 GNAQ

1.87e-052151230890659
Pubmed

Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5.

C5 C7

1.87e-052151215383587
Pubmed

Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.

GNA11 GNAQ

1.87e-05215129607776
Pubmed

Fcgamma-receptor signaling augments the LPS-stimulated increase in serum tumor necrosis factor-alpha levels.

FCER1G C5

1.87e-052151211247825
Pubmed

Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.

GNA11 GNAQ

1.87e-052151231726051
Pubmed

G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.

GNA11 GNAQ

1.87e-052151211438569
Pubmed

GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.

GNA11 GNAQ

1.87e-052151237802294
Pubmed

Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.

GNA11 GNAQ

1.87e-052151226628681
Pubmed

The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.

GNA11 GNAQ

1.87e-052151217552882
Pubmed

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression.

GSK3B AXIN1

1.87e-052151210581160
Pubmed

Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.

GNA11 GNAQ

1.87e-052151231173078
Pubmed

Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium.

MAP1B GSK3B

1.87e-05215129570753
Pubmed

Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.

GNA11 GNAQ

1.87e-052151229209985
Pubmed

TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.

TNIK GSK3B

1.87e-052151223035106
Pubmed

Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration.

TNC TNN

1.87e-052151224101721
Pubmed

The GAUGAA Motif Is Responsible for the Binding between circSMARCA5 and SRSF1 and Related Downstream Effects on Glioblastoma Multiforme Cell Migration and Angiogenic Potential.

SMARCA5 SRSF1

1.87e-052151233562358
Pubmed

Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.

GNA11 GNAQ

1.87e-052151215175381
Pubmed

Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.

GNA11 GNAQ

1.87e-052151225280020
Pubmed

GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.

GNA11 GNAQ

1.87e-052151227498141
Pubmed

Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.

GNA11 GNAQ

1.87e-052151228982892
Pubmed

Mutations in GNA11 in uveal melanoma.

GNA11 GNAQ

1.87e-052151221083380
Pubmed

GNAQ and GNA11 mutations in uveal melanoma.

GNA11 GNAQ

1.87e-052151225304237
Pubmed

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.

GNA11 GNAQ

1.87e-052151228301547
Pubmed

Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.

GNA11 GNAQ

1.87e-052151216847339
Pubmed

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer.

TFEB YEATS4

1.87e-052151226307679
Pubmed

Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.

GNA11 GNAQ

1.87e-052151229570931
Pubmed

Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.

GNA11 GNAQ

1.87e-052151210818132
Pubmed

Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.

GNA11 GNAQ

1.87e-052151226272756
Pubmed

NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.

GNA11 GNAQ

1.87e-052151231461351
Pubmed

Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.

GNA11 GNAQ

1.87e-052151223634288
Pubmed

PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma.

PFKFB4 ICMT

1.87e-052151235914811
Pubmed

Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans.

GSK3B AXIN1

1.87e-052151217601533
Pubmed

Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.

GNA11 GNAQ

1.87e-052151226368812
Pubmed

Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.

GNA11 GNAQ

1.87e-052151217482476
Pubmed

Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.

GNA11 GNAQ

1.87e-052151224141786
Pubmed

Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.

GNA11 GNAQ

1.87e-052151237102682
Pubmed

Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.

GNA11 GNAQ

1.87e-05215127492305
Pubmed

Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β.

IDH2 GSK3B

1.87e-052151224549719
Pubmed

Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.

GNA11 GNAQ

1.87e-052151224308950
Pubmed

Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.

GNA11 GNAQ

1.87e-052151222562663
Pubmed

Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.

GNA11 GNAQ

1.87e-052151211826096
Pubmed

Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2.

NEB C5

1.87e-05215121683831
Pubmed

Blue nevi and variants: an update.

GNA11 GNAQ

1.87e-052151221366456
Pubmed

Recombinant C345C and factor I modules of complement components C5 and C7 inhibit C7 incorporation into the complement membrane attack complex.

C5 C7

1.87e-052151215879120
Pubmed

In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.

GNA11 GNAQ

1.87e-052151235580369
Pubmed

Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations.

GNA11 GNAQ

1.87e-052151237750536
Pubmed

Glycogen synthase kinase-3 and Axin function in a beta-catenin-independent pathway that regulates neurite outgrowth in neuroblastoma cells.

GSK3B AXIN1

1.87e-052151214664817
Pubmed

Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.

GNA11 GNAQ

1.87e-052151226778290
Pubmed

Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.

GNA11 GNAQ

1.87e-052151230936140
Pubmed

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.

GSK3B AXIN1

1.87e-052151212554650
Pubmed

Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11.

GNA11 GNAQ

1.87e-052151223778528
Pubmed

High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.

GNA11 GNAQ

1.87e-052151222977135
Pubmed

The adhesion modulating properties of tenascin-W.

TNC TNN

1.87e-052151222211116
Pubmed

An experimental strategy to probe Gq contribution to signal transduction in living cells.

GNA11 GNAQ

1.87e-052151233639168
Pubmed

GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.

GNA11 GNAQ

1.87e-052151232064597
Pubmed

Mutational analysis of GNAQ and GNA11 to aid therapy management of a choroidal melanoma metastatic to the contralateral orbit.

GNA11 GNAQ

1.87e-052151223572068
Pubmed

Low mutational burden of eight genes involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 pathways in female genital tract primary melanomas.

GNA11 GNAQ

1.87e-052151225695059
Pubmed

Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1.

GNA11 GNAQ

1.87e-052151212351712
Pubmed

Cardiac remodeling in Gαq and Gα11 knockout mice.

GNA11 GNAQ

1.87e-052151226476043
Pubmed

C5b-9 glomerular deposition and tubular alpha3beta1-integrin expression are implicated in the development of chronic lesions and predict renal function outcome in immunoglobulin A nephropathy.

ITGA3 C5

1.87e-052151219230171
Pubmed

Early-onset hypertension associated with extensive cutaneous capillary malformations harboring postzygotic variants in GNAQ and GNA11.

GNA11 GNAQ

1.87e-052151236440997
GeneFamilyFibronectin type III domain containing

FNDC3B MYOM1 TNC MYOM3 OBSCN PTPRO TNN USH2A

2.34e-06160978555
GeneFamilyRNA binding motif containing

SART3 SRSF1 RBM45 RNPC3 SNRNP35 HNRNPA3 ESRP2

1.49e-04213977725
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3C SEMA4G SEMA3D

1.60e-0420973736
GeneFamilyTopoisomerases

TOP2B TOP3A

4.21e-0469721050
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYOM1 MYOM3

7.81e-048972658
GeneFamilyTudor domain containing

TDRD15 TDRD6 AKAP1

1.02e-0337973780
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_DN

TNIK ZMYND11 ACADSB RBL1 POLA1 TMEM14A ZNF254 HNRNPA3 RRM1 PTGDR ANKRD36B RPL23 YEATS4 P2RX5 PARP16 EIF4A2 GID8 TOP2B

2.05e-05101215018M40864
CoexpressionGSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_DN

SRSF1 MYOM1 POLA1 KBTBD8 RRM1 PANK1 DSCC1 USP6NL

2.08e-052001508M9779
CoexpressionRHEIN_ALL_GLUCOCORTICOID_THERAPY_DN

TMEM14A PRDX4 HNRNPA3 IDH2 SSRP1 RRM1 PTGDR RPL23 SMS ATIC

5.41e-0536815010M1859
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_DN

SEMA3C ZMYND11 SRSF1 ACADSB TNC RRM1 LYST GSK3B TCERG1 GNAQ TOP2B

1.07e-0448115011M3898
CoexpressionGSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_DN

RPS6KA1 HUWE1 ZZEF1 ESRP2 GNAQ USH2A SMC1B

1.16e-041901507M5666
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_CD5_POS_CCL22_POS_MATURE_B_CELL

TFEB ZMYND11 EMC1 TMEM14A PRDX4 KBTBD8 HUWE1 ADPRH MYO3A ICMT SMS ATIC VARS1

1.24e-0466615013M45778
CoexpressionGSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP

SMARCA5 MAN1A1 TNC IDH2 P2RX5 DENND6B MAP4K4

1.36e-041951507M8134
CoexpressionGSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_UP

FBXO40 EMC1 SH3BP2 ZBTB1 EFHC2 CFAP92 TAB1

1.36e-041951507M9873
CoexpressionGSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP

TNIK RPS6KA1 LYST AXIN1 RPL23 ICMT ATIC

1.45e-041971507M9969
CoexpressionGSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP

TNIK POLA1 HNRNPA3 ADNP2 GSK3B VPS13D GNAQ

1.45e-041971507M7403
CoexpressionGSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN

TFEB NLRP12 RPS6KA1 PFKFB4 ICMT VPS35 MTCH1

1.49e-041981507M5861
CoexpressionGSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP

TMEM14A ZZEF1 AXIN1 ANKRD36B P2RX5 AKAP1 CNOT3

1.54e-041991507M3257
CoexpressionGSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN

TFEB NLRP12 RPS6KA1 PFKFB4 ICMT VPS35 MTCH1

1.54e-041991507M5874
CoexpressionGSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP

TFEB SH3BP2 PFKFB4 GNAQ TACSTD2 VARS1 USP6NL

1.54e-041991507M7156
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP

FNDC3B TNFSF9 CEMIP VPS13D SMS MAP4K4 HERC5

1.54e-041991507M7951
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP

IDH2 SSRP1 ZZEF1 GSK3B TCERG1 ICMT GNA11

1.54e-041991507M5254
CoexpressionGSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN

MYO3A YEATS4 PTPRO ATIC ALDH3A1 GPSM1 TOP2B

1.54e-041991507M7824
CoexpressionGSE7852_TREG_VS_TCONV_THYMUS_DN

WNT7A ZZEF1 LYST CDC37L1 SEMA4G CDYL2 CNOT3

1.54e-041991507M5732
CoexpressionGSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP

SRSF1 TNFSF9 SNRNP35 GTF3C5 SMS STIP1 VARS1

1.59e-042001507M8049
CoexpressionGSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN

RANBP10 RNPC3 IDH2 SYF2 TEC LYST MOCS2

1.59e-042001507M3674
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN

RBL1 POLA1 SNRNP35 IDH2 VPS13D STIP1 AKAP1

1.59e-042001507M5212
CoexpressionGSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN

SART3 CAPN6 TTC14 PTGDR LYST PROM1 BMP7

1.59e-042001507M9067
CoexpressionGSE3982_NEUTROPHIL_VS_BASOPHIL_DN

SEMA3C P2RX5 PTPRO FIBP MAIP1 DSCC1 MOCS2

1.59e-042001507M5525
CoexpressionGSE3982_DC_VS_NEUTROPHIL_UP

RRM1 PTPRO CSTF3 TAB1 ATIC TACSTD2 MOCS2

1.59e-042001507M5461
CoexpressionGSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN

SRSF1 RBM45 RNPC3 KBTBD8 ADNP2 CSTF3 GPSM1

1.59e-042001507M6975
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1|TCGA-Endometrium / Sample_Type by Project: Shred V9

POLA1 ADNP2 RRM1 PANK1 CEMIP NOM1 LRP4 TOP3A

3.26e-071931518c2673d86f7d7b849788036032a93a6d136a70040
ToppCellB_cell_maturation-CD34+_pro-B|B_cell_maturation / Lineage and Cell class

IDH2 SSRP1 RRM1 YEATS4 SMS GNAQ DSCC1 TOP2B

3.96e-0719815185737606e5e3dc56f11fdf70166caf4ba4a81bc9d
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEBP2 ESRP2 SEMA3D LRP4 GID8 HEPHL1 TACSTD2

1.69e-06167151702c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBXO40 MYOM1 MAP1B MYOM3 OBSCN LAMA2 ADCY5

3.96e-061901517918ad5037881212008f9f69d5df5da91fd01422c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

FBXO40 MYOM1 MYOM3 OBSCN LAMA2 CASZ1 GPSM1

3.96e-061901517fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3C TNC ADCY5 PROM1 SEMA3D LRP4 C7

4.10e-06191151714057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC LAMA2 NEB ADCY5 HEPH CEMIP C7

4.39e-0619315175bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

TNIK FBXO40 MYOM1 MYOM3 OBSCN ADCY5 CASZ1

4.70e-061951517f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TNC MMP28 BMP7 CFAP92 EEPD1 LRP4 MAIP1

5.19e-061981517bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TNC MMP28 BMP7 CFAP92 EEPD1 LRP4 MAIP1

5.19e-0619815176372e65242236c497d9b3be147092897c1609d22
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA3C OLFML2B CAPN6 LAMA2 NEB PROM1 SEMA3D

5.19e-06198151755e583321f60c95898d93cd0d2615c6692db52ec
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFSF9 TNC ITGA3 CEMIP BMP7 ALDH3A1 TACSTD2

5.19e-061981517fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNC OBSCN ITGA3 CEMIP BMP7 ALDH3A1 TACSTD2

5.37e-06199151794a7867e800df352731796de8c24cba133c29622
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B COL6A6 OLFML2B PRDX4 CAPN6 C7 MTCH1

5.37e-0619915179846d6a31635fde759d55674631c11ab9270a603
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HNRNPA3 IDH2 SSRP1 RRM1 YEATS4 SMS DSCC1

5.37e-06199151799778178e3ec121802db938db8c5475d19b43fec
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

FNDC3B SEMA3C MAP1B TNC ADCY5 PROM1 SEMA3D

5.55e-062001517c5e051f1aac8dda376c342a9932785a23450e073
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SEMA3C MAP1B TNC OLFML2B LAMA2 ADCY5 PROM1

5.55e-06200151767dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellE17.5-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYOM3 CEMIP KBTBD4 LRP4 ABCB11 ALDH3A1

1.24e-051501516201d5b68e71c6c003285428be96c488e6d526edf
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NWD1 PFKFB4 RRM1 FCER1G PTPRO SMC1B

1.86e-0516115168937f6b92cb2a93ea8c4780d9200a518c3112e53
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TDRD15 ACY3 EFHC2 PROM1 ABCB11 TEC

1.99e-05163151603b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3BP2 TMPRSS11F AXIN1 FCER1G DENND6B VARS1

1.99e-051631516f558ad9569e5137e62a601ba4f073e69ed8f8650
ToppCellfacs-BAT-Fat-3m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 TMEM43 PFKFB4 LYST FCER1G PTPRO

2.13e-051651516bfe330751d34813af7540765b490406078c40da7
ToppCellfacs-BAT-Fat-3m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 TMEM43 PFKFB4 LYST FCER1G PTPRO

2.13e-0516515168bdeacbb47948fabae2575689f811a9fad47f779
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NLRP12 OBSCN LAMA2 BMP7 LRP4 C7

2.36e-051681516d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

POLA1 PRDX4 TBC1D7 RRM1 DSCC1 TOP3A

2.69e-0517215167c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3C TNC LAMA2 PROM1 LRP4 C7

3.81e-05183151612daaea821e49bc94a01e2496331e92a80d27339
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A6 OLFML2B CAPN6 TMEM43 SEMA3D C7

3.93e-0518415164d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBXO40 MYOM1 MYOM3 OBSCN LAMA2 ADCY5

4.05e-051851516549eeb521c3985bff396ea0f202db21822efa51f
ToppCellfacs-Skin-Anagen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPA3 TMPRSS11F ESRP2 SEMA3D BMP7 TACSTD2

4.17e-0518615169a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD1 TNC SH3BP2 HEPH BMP7 LRP4

4.30e-051871516dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD1 TNC SH3BP2 HEPH BMP7 LRP4

4.30e-051871516ae90c263f80c36a410150d499e268d198944a3d9
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

TNIK FBXO40 MYOM3 OBSCN ADCY5 CASZ1

4.30e-05187151678cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

TNIK FBXO40 MYOM1 MYOM3 OBSCN CASZ1

4.56e-0518915169c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

FBXO40 MYOM1 MYOM3 OBSCN LAMA2 CASZ1

4.56e-0518915165e80c47f63980904c4c1ff02c201b67b456a0974
ToppCelldroplet-Limb_Muscle-nan-3m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLA1 ADNP2 PFKFB4 ITGA3 ZZEF1 CDYL2

4.56e-05189151616a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell368C-Lymphocytic-NK_cells-Proliferating_NK_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

POLA1 SNRNP35 IDH2 ANKRD36B DSCC1 ZNF222

4.56e-05189151631d34bc75d4457fca197e1766922e987dbd5f8a9
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3C MAP1B TNC ADCY5 PROM1 LRP4

4.56e-05189151645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 IFI16 C7

4.70e-0519015161121eb607a984c59fbffe7220837fc178745aa55
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TNIK FBXO40 MYOM1 MYOM3 OBSCN LAMA2

4.70e-051901516de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 IFI16 C7

4.70e-051901516048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NWD1 MAP1B EFHC2 PROM1 VWA3B ALDH3A1

4.84e-05191151628caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

MAN1A1 ACY3 IDH2 PROM1 GPSM1 TOP2B

4.84e-05191151632f2537c97c9984629d61c6f34a337f555146ad4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK SMARCA5 MAP1B COL6A6 LAMA2 C7

4.84e-0519115167d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 HEPH C7

4.84e-051911516107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NWD1 MAP1B EFHC2 PROM1 VWA3B ALDH3A1

4.84e-05191151615b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 HEPH C7

4.84e-051911516bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NWD1 MAP1B EFHC2 PROM1 VWA3B ALDH3A1

4.84e-051911516fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B SEMA3C TNC ITGA3 EEPD1 MAP4K4

4.98e-0519215168b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ACY3 IDH2 RPL23 CFAP92 DENND6B ATIC

4.98e-0519215163107ac48e1d9faaea96f07332ffe611e4ebef1a7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B TNC OLFML2B LAMA2 CEMIP C7

5.12e-051931516dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNC POLA1 OLFML2B PRDX4 RRM1 DSCC1

5.12e-051931516f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B TNC OLFML2B LAMA2 CEMIP C7

5.12e-051931516e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C HNRNPA3 TMEM43 EIF4A2 STIP1 TOP2B

5.27e-0519415164d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNC POLA1 PRDX4 CAPN6 RRM1 DSCC1

5.27e-051941516af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 EEPD1 C7

5.27e-05194151690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MAP1B TNC LAMA2 EEPD1 C7

5.27e-051941516df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell18-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

SMARCA5 MMP28 WNT7A ITGA3 C5 TACSTD2

5.27e-051941516b45f1e80074a19245bc5dc4b3a583419a1904404
ToppCellDiffer-Basal|World / shred by cell class for mouse tongue

ESRP2 BMP7 LRP4 ALDH3A1 USP6NL MOCS2

5.27e-051941516851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

FBXO40 MYOM1 MYOM3 OBSCN LAMA2 CASZ1

5.43e-05195151675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 MAP1B COL6A6 LAMA2 NEB C7

5.43e-0519515165c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellILEUM-non-inflamed-(1)_Highly_activated_T_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IDH2 SSRP1 RRM1 FIBP SMS DSCC1

5.58e-0519615166a415a2574bd84bd825a2bd6c8e3632a433ff7cf
ToppCellwk_20-22-Epithelial-Distal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SMARCA5 WNT7A ITGA3 ESRP2 C5 TACSTD2

5.58e-051961516cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RBL1 IDH2 RRM1 YEATS4 DSCC1 MOCS2

5.58e-051961516de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

TNC CEMIP BMP7 LRP4 ALDH3A1 TACSTD2

5.74e-05197151624360b660000bdfb999d58fbf4e29585a97e1785
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B TNC OLFML2B LAMA2 CEMIP C7

5.74e-0519715164cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC ITGA3 CEMIP BMP7 ALDH3A1 TACSTD2

5.74e-0519715162430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCellfacs-Diaphragm-Limb_Muscle-3m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 OLFML2B HNRNPA3 LAMA2 GSK3B MAP4K4

5.74e-051971516b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C SRSF1 HUWE1 VPS35 MAP4K4 TOP2B

5.91e-0519815162f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TNC IFI16 CEMIP BMP7 LRP4 ALDH3A1

5.91e-0519815164235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C SRSF1 RPS6KA1 ITGA3 VPS35 TOP2B

5.91e-05198151622559b161e67b49fe8028bfaf861e069063599f5
ToppCellImmune_cells-large_pre-B.|Immune_cells / Lineage and Cell class

SMARCA5 PRDX4 RRM1 STIP1 ATIC AKAP1

5.91e-051981516bc9ceefadb153907d2854d1f736d17349003cb31
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C SRSF1 HUWE1 VPS35 MAP4K4 TOP2B

5.91e-051981516f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B COL6A6 OLFML2B CAPN6 SEMA3D C7

5.91e-051981516d9ffc6589ed510ffa60c591f2a0fe123210f1455
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNC OBSCN CEMIP BMP7 ALDH3A1 TACSTD2

5.91e-0519815165374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 HEBP2 EFHC2 PROM1 ALDH3A1 TACSTD2

5.91e-051981516d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

OLFML2B OBSCN EFHC2 C7 ALDH3A1

6.02e-05122151537612ad087d9c11d4a3466244ab36224de31930b
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C SRSF1 HUWE1 VPS35 MAP4K4 TOP2B

6.07e-0519915168d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B COL6A6 OLFML2B CAPN6 SEMA3D C7

6.07e-051991516bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNRNPA3 PTGDR EFHC2 PROM1 AXDND1 MOCS2

6.07e-051991516d1a3eaef9e84d0572776e8468099d669b8a98ef7
ToppCell3'-Adult-Appendix|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNRNPA3 PTGDR EFHC2 PROM1 AXDND1 MOCS2

6.07e-05199151632ff62019535ea30059b63a2686c565baa54bfee
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPA3 IDH2 SSRP1 RRM1 IFI16 TOP2B

6.07e-0519915168e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCell3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNRNPA3 PTGDR EFHC2 PROM1 AXDND1 MOCS2

6.07e-0519915167ff034b384f8fa4e027025aa5bf8cb856d793b18
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A6 OLFML2B PRDX4 CAPN6 LAMA2 C7

6.07e-05199151683383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell3'-Adult-Appendix-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNRNPA3 PTGDR EFHC2 PROM1 AXDND1 MOCS2

6.07e-05199151677bdd3df106c05acc173555ce13243d93c50e94d
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SEMA3C MAP1B OLFML2B LAMA2 ADCY5 PROM1

6.24e-052001516f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

COL6A6 TNC LAMA2 CEMIP C7 GPSM1

6.24e-052001516aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

FNDC3B SEMA3C TNC PROM1 SEMA3D LRP4

6.24e-0520015169d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B COL6A6 TNC OLFML2B LAMA2 C7

6.24e-0520015162e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

TNC CEMIP BMP7 LRP4 ALDH3A1 TACSTD2

6.24e-0520015165cea84581201cee7ba8141b96e65864f4fd67113
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TNC WNT7A ITGA3 BMP7 ALDH3A1 TACSTD2

6.24e-052001516592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

SEMA3C TNC OLFML2B LAMA2 ADCY5 PROM1

6.24e-0520015165ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A6 TNC LAMA2 CEMIP C7 GPSM1

6.24e-052001516a510deaada669e690329183e18df02870bd204b3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

HEBP2 OBSCN CDK11A WDR19 SEMA3D DYRK3

6.24e-0520015166b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SEMA3C MAP1B TNC ADCY5 PROM1 LRP4

6.24e-05200151608bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNC OBSCN ITGA3 CEMIP ALDH3A1 TACSTD2

6.24e-0520015169da214f756a03516eaafde00289b90f69623b9f3
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

SEMA3C MAP1B TNC OLFML2B PROM1 LRP4

6.24e-05200151602cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNC WNT7A ITGA3 BMP7 ALDH3A1 TACSTD2

6.24e-0520015168cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNC ITGA3 CEMIP BMP7 ALDH3A1 TACSTD2

6.24e-0520015162a9d715aba8bdef2341b0d44ff60825c074a4b03
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

SEMA3C MAP1B OLFML2B LAMA2 ADCY5 PROM1

6.24e-0520015168bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MAP1B TNC OLFML2B LAMA2 HEPH TNN

6.24e-0520015169bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
DrugTrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

TNIK MAP1B TNFSF9 LYST WDR19 BMP7 PARP16 ZNF222 DYRK3

2.03e-0617314895594_UP
Drug2-chloro-dATP

POLA1 RRM1 TOP2B TOP3A

3.82e-06171484CID000122644
DrugMethylatropine nitrate [52-88-0]; Down 200; 11uM; HL60; HT_HG-U133A

TNIK TFEB TNFSF9 PFKFB4 AXIN1 KBTBD4 PARP16 GNA11 DYRK3

4.99e-0619314893116_DN
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; HL60; HT_HG-U133A

RANBP10 EMC1 IDH2 AXIN1 VPS13D PARP16 C5 TAF1 TOP3A

5.20e-0619414892430_DN
DrugThiocolchicoside [602-41-5]; Down 200; 7uM; HL60; HG-U133A

SMARCA5 EMC1 SRSF1 TMEM14A SH3BP2 BMP7 MAP4K4 TOP3A HERC5

5.42e-0619514891726_DN
DrugBufexamac [2438-72-4]; Down 200; 18uM; HL60; HT_HG-U133A

SRSF1 TEC NEB ZZEF1 IFI16 GTF3C5 GNA11 ZNF222 DYRK3

5.65e-0619614892382_DN
Drugestradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A

ZMYND11 TNC SH3BP2 LAMA2 HUWE1 IFI16 ADPRH LRP4 USP6NL

5.89e-0619714894465_UP
DrugIsoxicam [34552-84-6]; Down 200; 12uM; PC3; HT_HG-U133A

ACADSB LYST GTF3C5 AXIN1 VPS13D P2RX5 TAB1 ALDH3A1 ZNF222

6.66e-0620014897268_DN
Drugphlorobenzophenone

LYST ICMT

4.20e-0521482CID000077093
DrugClofarabine

POLA1 RRM1

4.20e-0521482DB00631
DrugAlfadolone acetate [23930-37-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A

MAP1B SH3BP2 LYST GTF3C5 SEMA4G KBTBD4 AKAP1 DYRK3

4.40e-0519614886506_DN
DrugAC1L1U53

TNIK NLRP12 POLA1 LYST ABCB11

4.44e-05601485CID000060907
Drugclofibrate; Down 200; 150uM; MCF7; HG-U133A

SRSF1 SH3BP2 ASCC1 LAMA2 GTF3C5 KBTBD4 LRP4 GNA11

4.57e-051971488263_DN
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

SEMA3C MAP1B TNC ZZEF1 ZBTB1 TAF1 AKAP1 HERC5

4.57e-0519714886758_DN
DrugIopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A

RANBP10 EMC1 SH3BP2 ZBTB1 CASZ1 AXIN1 HERC5 DYRK3

4.57e-0519714886842_DN
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A

TNIK EMC1 ACADSB SH3BP2 IDH2 LYST VPS13D CNOT3

4.57e-0519714885746_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A

FBXO40 TNC LAMA2 HUWE1 NEB ZZEF1 VPS13D LRP4

4.73e-0519814885865_UP
Drug(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; PC3; HT_HG-U133A

SRSF1 TNFSF9 IDH2 CASZ1 SEMA4G VPS13D C5 ALDH3A1

4.73e-0519814884020_DN
DrugAntazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

TNIK MAN1A1 RBL1 SYF2 RPL23 P2RX5 TAF1 HERC5

4.90e-0519914887128_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A

SART3 ACADSB SH3BP2 TEC NEB CASZ1 AXIN1 DYRK3

4.90e-0519914882402_DN
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; HL60; HG-U133A

SART3 SMARCA5 ASCC1 IFI16 YEATS4 KBTBD4 TCERG1 DSCC1

4.90e-0519914881776_DN
DrugTolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A

SMARCA5 EMC1 LYST AXIN1 CEMIP PARP16 TAF1 TOP3A

4.90e-0519914881500_UP
DrugTolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

ZMYND11 EMC1 SRSF1 ACADSB NEB VPS13D YEATS4 CNOT3

5.08e-0520014884088_DN
DrugNC-190

POLA1 TOP2B TOP3A

5.67e-05121483CID000129234
Diseasefasting blood glucose measurement

NLRP12 MAN1A1 RPS6KA1 ADCY5 BMP7 NOM1 ABCB11 MAIP1 VARS1

1.55e-052871489EFO_0004465
DiseasePhakomatosis cesioflammea

GNA11 GNAQ

2.50e-0521482C3838883
DiseaseCongenital hemangioma

GNA11 GNAQ

2.50e-0521482C0235753
DiseasePort-wine stain with oculocutaneous melanosis

GNA11 GNAQ

2.50e-0521482C1274879
Diseasegamma-interferon-inducible protein 16 measurement

NLRP12 IFI16

2.50e-0521482EFO_0801617
DiseasePrimary Peritonitis

GSK3B C5

7.47e-0531482C1449646
DiseaseSecondary Peritonitis

GSK3B C5

7.47e-0531482C1449647
DiseasePeritonitis

GSK3B C5

7.47e-0531482C0031154
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.49e-0441482EFO_0020830
DiseaseMalignant melanoma of iris

GNA11 GNAQ

2.47e-0451482C0346373
DiseaseMalignant melanoma of choroid

GNA11 GNAQ

2.47e-0451482C0346388
DiseasecGMP-specific 3',5'-cyclic phosphodiesterase measurement

FABP2 C7

2.47e-0451482EFO_0008081
DiseaseSH3 domain-binding protein 2 measurement

NLRP12 SH3BP2

2.47e-0451482EFO_0802063
Diseasecyclin-dependent kinase 8:cyclin-c complex measurement

NLRP12 C7

3.70e-0461482EFO_0020297
Diseasetestis-expressed sequence 29 protein measurement

NLRP12 C7

6.86e-0481482EFO_0802125
DiseaseUveal melanoma

GNA11 GNAQ

6.86e-0481482C0220633
Diseaseretinal detachment, retinal break

KBTBD8 LAMA2 AXDND1

7.19e-04351483EFO_0005773, EFO_0010698
DiseaseAutoinflammatory disorder

NLRP12 POLA1 SH3BP2

7.19e-04351483C3860213
Diseaseleucine-rich repeat serine/threonine-protein kinase 2 measurement

NLRP12 C7

8.79e-0491482EFO_0021876
Diseaseheterogeneous nuclear ribonucleoprotein q measurement

NLRP12 C7

8.79e-0491482EFO_0020443
Diseasetrimethyllysine measurement

TBC1D7 GNAQ

1.33e-03111482EFO_0009134
Diseasemelanoma

TNC PTPRO GNA11 STIP1 GNAQ USP6NL

1.62e-032481486C0025202
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

RPS6KA1 ZZEF1

2.19e-03141482EFO_0006830, EFO_0006896
Diseasecancer (implicated_via_orthology)

RBL1 ITGA3 SSRP1 AXIN1 GPSM1 TOP2B

2.39e-032681486DOID:162 (implicated_via_orthology)
Diseasehigh grade glioma (biomarker_via_orthology)

TNC YEATS4

2.51e-03151482DOID:3070 (biomarker_via_orthology)
DiseaseHypertrophic Cardiomyopathy

MYOM1 OBSCN IDH2

2.97e-03571483C0007194
Diseasecognitive behavioural therapy

WNT7A NEB TCERG1

3.12e-03581483EFO_0007820
Diseaseglucose measurement

TNIK PTGDR ADCY5 AXIN1 MYO3A ABCB11 GPSM1

3.15e-033801487EFO_0004468
DiseaseCongenital Intestinal Aganglionosis

SEMA3C SEMA3D

3.23e-03171482C3661523
DiseasePost-Traumatic Osteoporosis

IDH2 ADCY5 ATIC

3.60e-03611483C0751406
DiseaseOsteoporosis, Senile

IDH2 ADCY5 ATIC

3.60e-03611483C0029459
DiseaseOsteoporosis, Age-Related

IDH2 ADCY5 ATIC

3.60e-03611483C0001787
Diseaseadenosine monophosphate measurement

RRM1 AKAP1

3.63e-03181482EFO_0010454
DiseaseOsteoporosis

IDH2 ADCY5 ATIC

3.94e-03631483C0029456
Diseasecystathionine measurement

TEC TEC

4.04e-03191482EFO_0010474

Protein segments in the cluster

PeptideGeneStartEntry
IRYVDYGGYKRVKVD

AKAP1

791

Q92667
VSGFIHKIYEEKYAD

ADAM5

101

Q6NVV9
AAYYEKGVAFVQTEK

ACY3

286

Q96HD9
FSKYEEYIRKLKAGE

CASZ1

236

Q86V15
FYGEDAKKSRDYGRI

ALDH3A1

271

P30838
QTYVYEGVEAKRIFK

FABP2

116

P12104
YYKANVAKAGLVDDF

ATP5PD

56

O75947
YRIFEKDSKFYLEGE

SH3BP2

511

P78314
FTDYELKAYAKAGVV

ABCB11

266

O95342
FALKTRADKEGDYYV

ACADSB

186

P45954
EKYFRDAKIGTIYEG

ACADSB

401

P45954
YTAEGKYIFKERESF

ASCC1

326

Q8N9N2
VFSRDVYGKLAEDYA

ANKRD36B

211

Q8N2N9
KVRYYRLKTAGFTDD

CFAP92

201

Q9ULG3
KKYSKQVDDRFGAYV

ADCY5

751

O95622
FGYVYFRQVKDSSVK

DENND6B

131

Q8NEG7
GEAVTAAEFRIYKDY

BMP7

166

P18075
LSTEVVYKKGQDYRF

CEMIP

371

Q8WUJ3
EYREYIGGFKKVEDL

EEPD1

66

Q7L9B9
YEGRSYEEKKQFLKD

ADNP2

1046

Q6IQ32
KKEGFTFEYRYLEDR

CNOT3

736

O75175
FSKDDKYVYVGLKDR

NWD1

1441

Q149M9
GIYYFEVKIVSKGRD

RANBP10

101

Q6VN20
YTEEDLREKFKVYGD

RBM45

131

Q8IUH3
VIYRAYYGAFKDVKE

PTGDR

281

Q13258
GYSDEDKRGFTKLVY

GNAQ

66

P50148
KKRGEKDETEYEYSG

MAP4K4

311

O95819
VGGYYYEKIERTTKS

MAP1B

1901

P46821
TGDISIYYDEKGRKF

MAIP1

206

Q8WWC4
GYKKKYEEEVALRAT

KRT85

206

P78386
FLGRFDVAAEYYKKT

GPSM1

261

Q86YR5
EKYYVDSVKGRFTIS

IGHV3-7

76

P01780
YESFLYRREKAAGEK

FLYWCH1

521

Q4VC44
ILREDGKVFDEKVYY

HEBP2

161

Q9Y5Z4
DRYKLGKVDQEFYKD

EFHC2

321

Q5JST6
YFERKEEVGGAIYVF

ITGA3

331

P26006
YEGKETALLVDRYKF

CSTF3

516

Q12996
GQYRRDVVKTYKSFE

PFKFB4

76

Q16877
RKAAITSYEKSDGVY

FCER1G

51

P30273
GYKKKYEEEVALRAT

KRT87P

21

A6NCN2
GKLKYAIYFEAREET

LAMA2

1251

P24043
YFKFVGRIVAKAVYD

HUWE1

4106

Q7Z6Z7
AKAGEKYKYEVEDFT

POLA1

41

P09884
AVEYKEKIYVLQGEF

KBTBD8

436

Q8NFY9
YVVKITGESKNYFFE

PTPRO

56

Q16827
AKFYETKGERDLIYA

PARP16

136

Q8N5Y8
SVKAVYEEFRRGFYK

HERC5

876

Q9UII4
QEFYKKYAEEALLAG

OBSCN

5801

Q5VST9
KSYRRKDGVFLYFED

RPL23

86

P62829
IHFFGEEYLEYKKRV

ICMT

256

O60725
KAYDGRFKDIFQEIF

IDH2

256

P48735
KKYVDEGEVYFELDA

DSCC1

251

Q9BVC3
LSDAKKRDIYDRYGE

DNAJB3

56

Q8WWF6
YEVALSDKGRDGKYK

FNDC3B

316

Q53EP0
YDVTYAKGQTREKAV

AXDND1

131

Q5T1B0
RYYFKKVSDEFDCGV

AXIN1

821

O15169
KARYFYNKVVTEADV

C5

251

P01031
GYSEEDKRGFTKLVY

GNA11

66

P29992
GEYRVLFYVDSEKLK

C7

311

P10643
KRYEALGEIITKYVY

FAM172A

96

Q8WUF8
YLVTEGFKEAAEKFR

GID8

36

Q9NWU2
RLRYFFYSSGEKKDE

GSK3B

111

P49841
TYGVVYRAKDKKTDE

CDK11A

436

Q9UQ88
KESLLRGIYAYGFEK

EIF4A2

41

Q14240
DTYKYLEEEYRKGAR

LYST

3206

Q99698
YGKLEAQEVKTVYTF

FBXO40

336

Q9UH90
QYKKVVYREYTDGEF

HEPHL1

781

Q6MZM0
VYREYTDGEFVEIKA

HEPHL1

786

Q6MZM0
FEVHKKNVRGEFTYY

IFI16

691

Q16666
SAYYLSGEEIFRKKA

MAN1A1

291

P33908
DKVRIKGYYAFKLAE

KLB

921

Q86Z14
YIQVFLKKDDSVGYR

EMC1

406

Q8N766
KGRYTELVEEKYKLF

CAPN6

201

Q9Y6Q1
REHVYDLFEKAVKDY

SART3

166

Q15020
AYRYEVLKIIGKGSF

DYRK3

206

O43781
FRLFFQKAKAEEEGY

CDC37L1

241

Q7L3B6
EEKRVYYVHDFDALK

COL6A6

586

A6NMZ7
VDKLVKDIYGGDYER

PANK1

471

Q8TE04
YRDKKYEEVRGLEDS

P2RX5

346

Q93086
ELRKEAEAFLEKYGY

MMP28

31

Q9H239
YYAFDEAFVREVLGK

FIBP

96

O43427
SFFTYAKYIVQVDGK

MTCH1

131

Q9NZJ7
KEESRSGANKYLYFV

RSPH6A

416

Q9H0K4
YKEKVEFGVLVSFAY

VARS1

506

P26640
RGVIEKYILKAYSED

USH2A

1981

O75445
KRYAKEGREFDYVIN

SMS

261

P52788
REYTEDGQVKKETRY

TMEM43

131

Q9BTV4
KVREYLSETYGNKFA

TFEB

91

P19484
KAERFYGKYTAEIKQ

SYF2

221

O95926
GYYRAIVTKLDDKSV

TDRD6

551

O60522
VRIGTDYKYTKIAVD

SEMA3C

421

Q99985
KAYARIGNSYFKEEK

STIP1

301

P31948
NGFRSYVDLYVKDKL

TOP2B

286

Q02880
GEFKELKLTDYRGKY

PRDX4

96

Q13162
RRIGDYKVKYGYTDI

TAB1

241

Q15750
KEVDIVFVDYGYQKR

TDRD15

826

B5MCY1
YEGRAEKKYRKGFID

TEC

41

P42680
NFEGKKVISLEYEAY

MOCS2

81

O96007
TIYVGRVKSFALKYD

RBL1

936

P28749
EAYGEKFVADYKKSA

RDH16

236

O75452
DAAYYFERDIKGESL

TACSTD2

221

P09758
KIYRTFRDEEGKEYV

TAF1

1166

P21675
IYVFRDRYKKGDANT

KBTBD4

476

Q9NVX7
YKKAVFREYTDGTFR

HEPH

781

Q9BQS7
IEETKKYGRTIIGYF

PROM1

736

O43490
VRKFDAIYKYGSEGK

NOM1

446

Q5C9Z4
YAKAKEADGRYKEAV

WDR19

901

Q8NEZ3
YIEVYKATGEEFVKI

ESRP2

326

Q9H6T0
SVYYEKVGFRGVEEK

TBC1D7

11

Q9P0N9
IRGITYYKAKVSEEE

OLFML2B

296

Q68BL8
GYIDLGVYKEDIIFK

SEMA3D

156

O95025
VYKYDGFRESEFEKL

SSRP1

71

Q08945
EAKKYIVQSGYFVEE

ADPRH

201

P54922
AEKDYVFDKRLRYSV

CDYL2

226

Q8N8U2
KKRGEKDETEYEYSG

TNIK

311

Q9UKE5
DADYLVYKVTDRFGF

USP6NL

36

Q92738
KYKENYGIRSSREFI

TMPRSS11F

71

Q6ZWK6
VQEKDLKYIFGRYVD

RNPC3

431

Q96LT9
AVGDDDKVYYFFTER

SEMA4G

231

Q9NTN9
DKYVVRYTSADGDTK

TNN

471

Q9UQP3
EYIRDKYITAKADFR

TCERG1

1006

O14776
EFEKLYASYEKQGRV

RRM1

366

P23921
KEEFYSRADALIGIY

SMC1B

1186

Q8NDV3
YLEVYLTDEFAKGRK

VPS35

76

Q96QK1
VYDKFSVGDAKTRYK

TNC

2086

P24821
YGAYRVSNDKRDVKV

TMEM14A

41

Q9Y6G1
SKGYAFIEYKEERAV

SNRNP35

91

Q16560
NSEDKIYGYRRFEKD

TTC14

636

Q96N46
SEKYRKLVSAVVEYG

VPS45

416

Q9NRW7
YKGKLFVFDERYALS

TSTD2

396

Q5T7W7
NLRDYFEKYGKIETI

HNRNPA3

141

P51991
DEAISDYFRKQYSKG

ATIC

186

P31939
KELVVAKAGVYYVFF

TNFSF9

131

P41273
REGLSKFNKIYEFDY

TOP3A

61

Q13472
RYYVEEDVSIKKSGR

ZBTB1

371

Q9Y2K1
NEGKYRSYEEFKADA

ZMYND11

206

Q15326
FRELGYVLKDKYNEA

WNT7A

221

O00755
TEKRYDYLEFTDARG

ZZEF1

1131

O43149
DIRTKDIEDVFYKYG

SRSF1

26

Q07955
DIEDVFYKYGAIRDI

SRSF1

31

Q07955
YKLKDSVYIFREGAL

GTF3C5

386

Q9Y5Q8
KAALVDYLDGKAVDY

TTC37

681

Q6PGP7
RDKTIESIYYFVVGD

VWA3B

231

Q502W6
VYGNVARYFGKKREE

YEATS4

26

O95619
VYNFEGEDYREKQKI

SMARCA5

711

O60264
EDSFQKAILRRYGKY

ZNF254

101

O75437
AEKLYKSEKYGRGFI

ZNF222

281

Q9UK12
SKAVYFLKSGDYVDR

VPS13D

4281

Q5THJ4
KDVYDDGKHVYLVTE

RPS6KA1

476

Q15418
DGKVYYTDVFLDVIR

LRP4

1396

O75096
EILGFSEAERKEYFY

NLRP12

361

P59046
EDKAAVFIQSKYRGY

MYO3A

1346

Q8NEV4
LSAYASVVVKRYKGE

MYOM1

361

P52179
GTEEGIRIFSKVKYY

MYOM3

1231

Q5VTT5
ASREIASEYKYKEGF

NEB

2541

P20929
RDIASEFKYKEGYRK

NEB

2786

P20929