Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcell-cell junction

MTSS1 PARD6G PARD3B SYNPO ITGB1 ZYX CD2 UBN1 PKD2 LRRC7 VAV1

1.46e-0459110211GO:0005911
GeneOntologyCellularComponentanchoring junction

MTSS1 PARD6G SRP68 PARD3B SYNPO PDPK2P ITGB1 ZYX CD2 UBN1 PKD2 LRRC7 MAP4K4 VAV1

2.75e-0497610214GO:0070161
GeneOntologyCellularComponentmCRD-mediated mRNA stability complex

PAIP1 PABPC3

3.49e-0461022GO:0106002
MousePhenoabnormal bile duct morphology

ANKS6 MAP3K14 RELB GAS2L2 PKD2

4.01e-0564845MP:0002928
MousePhenositus ambiguus

ANKS6 GAS2L2 PKD2

4.43e-0512843MP:0002767
DomainTranscription_factor_COE

EBF3 EBF1

1.76e-0441022IPR003523
DomainCOE_HLH

EBF3 EBF1

1.76e-0441022IPR032201
DomainCOE_DBD

EBF3 EBF1

1.76e-0441022IPR032200
DomainTranscription_factor_COE_CS

EBF3 EBF1

1.76e-0441022IPR018350
DomainCOE1_HLH

EBF3 EBF1

1.76e-0441022PF16423
DomainCOE1_DBD

EBF3 EBF1

1.76e-0441022PF16422
DomainCOE

EBF3 EBF1

1.76e-0441022PS01345
DomainIPT

EBF3 RELB EBF1

4.21e-04271023SM00429
DomainTIG

EBF3 RELB EBF1

6.36e-04311023PF01833
DomainIPT

EBF3 RELB EBF1

6.99e-04321023IPR002909
DomainBROMODOMAIN_2

BRWD3 BRD8 KMT2A

1.45e-03411023PS50014
DomainBROMO

BRWD3 BRD8 KMT2A

1.56e-03421023SM00297
DomainBromodomain

BRWD3 BRD8 KMT2A

1.56e-03421023IPR001487
Domain-

BRWD3 BRD8 KMT2A

1.56e-034210231.20.920.10
DomainI-BAR_dom

MTSS1 OPHN1

2.22e-03131022IPR013606
DomainPB1

PARD6G MAP3K3

2.57e-03141022SM00666
DomainPB1

PARD6G MAP3K3

2.57e-03141022PF00564
DomainPB1

PARD6G MAP3K3

2.57e-03141022PS51745
DomainPB1_dom

PARD6G MAP3K3

2.57e-03141022IPR000270
DomainRhoGAP

ARHGAP32 ARHGAP30 OPHN1

4.74e-03621023SM00324
DomainRhoGAP

ARHGAP32 ARHGAP30 OPHN1

4.95e-03631023PF00620
DomainRHOGAP

ARHGAP32 ARHGAP30 OPHN1

5.18e-03641023PS50238
DomainRhoGAP_dom

ARHGAP32 ARHGAP30 OPHN1

5.18e-03641023IPR000198
Domain-

ARHGAP32 ARHGAP30 OPHN1

5.18e-036410231.10.555.10
DomainCH

GAS2L2 NAV2 VAV1

5.41e-03651023SM00033
DomainHomeobox_Antennapedia_CS

HOXB3 HOXB6

5.80e-03211022IPR001827
DomainCH

GAS2L2 NAV2 VAV1

6.64e-03701023PF00307
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGAP32 NUMBL SAMD4B MAP3K14 PARD3B TBC1D22B FAM117B GIGYF1 MLXIP ZYX MAP3K3 FAM171A1 OTUD7A NAV2 KMT2A MAP4K4

6.97e-098611051636931259
Pubmed

Human transcription factor protein interaction networks.

ARHGAP32 SOBP MAML1 ZBTB9 SRP68 SRP72 RELB GIGYF1 BCOR ZHX2 ZNF503 BRD8 UBN1 ATXN7 PABPC3 CSNK2B G3BP2 KMT2A N4BP1 FOXI1

9.29e-0914291052035140242
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

ANKS6 NUMBL SAMD4B HNRNPM MAML1 SRP68 SRP72 RELB GIGYF1 ATG2A MLXIP ZYX MAP3K3 CSNK2B HOOK2 ESPL1 MAP4K4

1.45e-0810381051726673895
Pubmed

Splenic extramedullary hemopoiesis caused by a dysfunctional mutation in the NF-κB-inducing kinase gene.

MAP3K14 RELB MAP4K4

2.67e-083105322005462
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

REPS1 NUMBL HNRNPM SYNPO BCOR ZHX2 ITGB1 ZYX UBN1 ATXN7

1.02e-064441051034795231
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 PDE4A NUMBL EBF3 HNRNPM SYNPO BCOR LRIG2 FAM171A1 TRIM67 PABPC3 G3BP2 LRRC7 MAP4K4

1.26e-069631051428671696
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ARHGAP32 NUMBL DEPP1 SYBU GIGYF1 BCOR ZHX2 ZYX PTPRN ATXN7 CSNK2B

2.41e-066081051116713569
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PDE4A ANKS6 REPS1 PIEZO1 MAML1 RELB ATG2A MLXIP RYR1 ZNF503 GET4 UBN1 NAV2 ESPL1

6.14e-0611051051435748872
Pubmed

Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle.

RYR1 CLCN1

9.03e-062105221078869
Pubmed

Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.

HOXB6 CSNK2B

9.03e-062105210327653
Pubmed

Protein-induced conformational changes of RNA during the assembly of human signal recognition particle.

SRP68 SRP72

9.03e-062105217254600
Pubmed

Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.

PIEZO1 PKD2

9.03e-062105224157948
Pubmed

Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA.

SRP68 SRP72

9.03e-06210528388879
Pubmed

Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.

SRP68 SRP72

9.03e-062105228369529
Pubmed

A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans.

ITGB1 MAP4K4

9.03e-062105211967148
Pubmed

Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains.

SRP68 SRP72

9.03e-062105216672232
Pubmed

The Signal Recognition Particle Database (SRPDB).

SRP68 SRP72

9.03e-06210529399828
Pubmed

Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression.

LAMA4 KMT2A

9.03e-062105234958665
Pubmed

Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival.

MAP3K14 RELB

9.03e-062105222968463
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DYM NUMBL SOBP SAMD4B PARD3B SYNPO FAM117B ZNF362 ZHX2 ITGB1 BRWD3 HOXB6 ATXN7 PKD2 LRRC7 HOOK2

1.01e-0514891051628611215
Pubmed

Interaction network of human early embryonic transcription factors.

CLPP SOBP MAML1 ZBTB9 BCOR ZHX2 ZNF503 KMT2A

1.18e-05351105838297188
Pubmed

The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.

SYNPO ITGB1 ZYX

1.18e-0515105328536193
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARHGAP32 HNRNPM TBC1D22B GIGYF1 LRRC7 N4BP1 MAP4K4

1.58e-05263105734702444
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MAML1 ZBTB9 ZNF362 BCOR BRD8 CSNK2B KMT2A

1.78e-05268105733640491
Pubmed

Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice.

HOXB3 HOXB6 KMT2A

2.11e-051810539639506
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SAMD4B PARG BCOR THOC2 ZYX BRD8 UBN1 ATXN7 KMT2A ESPL1 MAP4K4

2.31e-057741051115302935
Pubmed

Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.

HOXB3 HOXB6 KMT2A

2.50e-0519105315741318
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PARG SRP68 ZNF362 THOC2 ZYX ZNF503 BRD8 UBN1 KMT2A SNX1

2.67e-056451051025281560
Pubmed

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

ARHGAP32 ZNF366 TBC1D22B ZNF446 ZYX MAP3K3 G3BP2 PKD2 MTUS2

2.69e-05514105929892012
Pubmed

Endothelial basement membrane laminin 511 is essential for shear stress response.

LAMA4 ITGB1

2.70e-053105227940654
Pubmed

Regulation of naive T cell function by the NF-kappaB2 pathway.

MAP3K14 RELB

2.70e-053105216732290
Pubmed

The NF-κB subunit RelB regulates the migration and invasion abilities and the radio-sensitivity of prostate cancer cells.

RELB ITGB1

2.70e-053105227121503
Pubmed

SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin.

ZYX VAV1

2.70e-05310528622875
Pubmed

Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy.

RYR1 CLCN1

2.70e-053105217158949
Pubmed

Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.

ZHX2 KMT2A

2.70e-053105219710696
Pubmed

The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.

EBF3 EBF1

2.70e-05310529151732
Pubmed

NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells.

MAP3K14 RELB

2.70e-053105212810685
Pubmed

Identification and recombinant production of human laminin alpha4 subunit splice variants.

LAMA4 ITGB1

2.70e-053105212445830
Pubmed

RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation.

MAP3K14 RELB

2.70e-053105218322009
Pubmed

A novel histone H4 arginine 3 methylation-sensitive histone H4 binding activity and transcriptional regulatory function for signal recognition particle subunits SRP68 and SRP72.

SRP68 SRP72

2.70e-053105223048028
Pubmed

Reconstitution of the human SRP system and quantitative and systematic analysis of its ribosome interactions.

SRP68 SRP72

2.70e-053105230649417
Pubmed

Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.

SRP68 SRP72

2.70e-053105227899666
Pubmed

The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor.

MAP3K14 MAP4K4

2.70e-053105211369779
Pubmed

The pivotal role of the alternative NF-kappaB pathway in maintenance of basal bone homeostasis and osteoclastogenesis.

MAP3K14 RELB

2.70e-053105219839765
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

EBF3 MAML1 ZBTB9 SRP68 SRP72 ZNF362 BCOR THOC2 ZYX ZNF503 GET4 G3BP2 KMT2A

2.88e-0511031051334189442
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PIEZO1 MTSS1 MAML1 SYNPO ATG2A BCOR NAV2 ESPL1 MAP4K4

3.36e-05529105914621295
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ARHGAP32 PARD6G PARD3B TBC1D22B ITGB1 FAM171A1 MAP4K4 SNX1

4.32e-05421105836976175
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

REPS1 SRP68 BCOR THOC2 ZYX BRD8 KMT2A MAP4K4 SNX1

4.47e-05549105938280479
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

ARHGAP32 DNAH3 MAP3K14 HNRNPM ZYX PABPC3 G3BP2

5.19e-05317105717620599
Pubmed

Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo.

LAMA4 ITGB1

5.40e-054105221979816
Pubmed

Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.

EBF3 EBF1

5.40e-05410529151733
Pubmed

NF-κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome.

MAP3K14 RELB

5.40e-054105228804991
Pubmed

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100.

MAP3K14 RELB

5.40e-054105227678221
Pubmed

Beta1 integrins control the formation of cell chains in the adult rostral migratory stream.

LAMA4 ITGB1

5.40e-054105217344408
Pubmed

Signal recognition particle components in the nucleolus.

SRP68 SRP72

5.40e-054105210618370
Pubmed

EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA.

EBF1 G3BP2

5.40e-054105235761386
Pubmed

Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection.

EBF3 EBF1

5.40e-054105212139918
Pubmed

S9, a 19 S proteasome subunit interacting with ubiquitinated NF-kappaB2/p100.

MAP3K14 MAP4K4

5.40e-054105212185077
Pubmed

Phosphoinositide-dependent kinase 1 regulates leukemia stem cell maintenance in MLL-AF9-induced murine acute myeloid leukemia.

PDPK2P KMT2A

5.40e-054105225769952
Pubmed

Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation.

MAP3K14 MAP4K4

5.40e-054105219874202
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ARHGAP32 NUMBL TBC1D22B ITGB1 ZYX NAV2 LRRC7 N4BP1 SNX1

5.58e-05565105925468996
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ARHGAP32 REPS1 NUMBL HNRNPM SRP68 SRP72 ITGB1 FAM171A1 LRRC7 MAP4K4

5.83e-057081051039231216
Pubmed

Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.

EBF3 EBF1 HOXB6

5.86e-0525105315229182
Pubmed

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.

EBF3 EBF1 CHST8

7.42e-0527105333760820
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

HNRNPM MAML1 ZBTB9 BCOR ATXN7 KMT2A N4BP1

7.90e-05339105730415952
Pubmed

Identification of Arx transcriptional targets in the developing basal forebrain.

EBF3 EBF1 ZNF503

8.29e-0528105318799476
Pubmed

The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin.

ITGB1 ZYX

8.97e-055105212417594
Pubmed

Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.

LAMA4 ITGB1

8.97e-055105219469865
Pubmed

Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1.

ITGB1 VAV1

8.97e-055105215872091
Pubmed

Induction of HoxB transcription by retinoic acid requires actin polymerization.

HOXB3 HOXB6

8.97e-055105219477923
Pubmed

The smallest near-infrared fluorescence complementation system for imaging protein-protein and RNA-protein interactions.

CSNK2B G3BP2

8.97e-055105235211278
Pubmed

Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.

EBF3 EBF1

8.97e-055105212917357
Pubmed

DOCK2 is required for chemokine-promoted human T lymphocyte adhesion under shear stress mediated by the integrin alpha4beta1.

ITGB1 VAV1

8.97e-055105217015707
Pubmed

Stem cell niche-specific Ebf3 maintains the bone marrow cavity.

EBF3 EBF1

8.97e-055105229563184
Pubmed

A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads.

SRP68 SRP72

8.97e-055105218089836
Pubmed

Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development.

EBF3 EBF1

8.97e-055105215261831
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

SOBP MAML1 BCOR ZNF503 LRIG2

1.01e-04152105538360978
Pubmed

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.

MTSS1 ZHX2 RYR1

1.02e-0430105320080650
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DYM REPS1 MAP3K14 SRP72 SYNPO RELB THOC2 ITGB1 HOXB6 UBN1 CSNK2B G3BP2 KMT2A HOOK2

1.11e-0414401051430833792
Pubmed

A human MAP kinase interactome.

ARHGAP32 HNRNPM LAMA4 SYNPO ZYX MAP3K3 NAV2 MAP4K4

1.17e-04486105820936779
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

REPS1 NUMBL PARG HNRNPM SRP68 BCOR THOC2 ZYX CSNK2B KMT2A SNX1

1.24e-049341051133916271
Pubmed

NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation.

MAP3K14 MAP4K4

1.34e-046105218439422
Pubmed

VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.

RELB ZHX2

1.34e-046105230026228
Pubmed

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development.

MAP3K14 RELB

1.34e-046105212810684
Pubmed

Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-κB pathway in TNF stimulation.

MAP3K14 MAP4K4

1.34e-046105223543740
Pubmed

β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance.

NUMBL ITGB1

1.34e-046105229653101
Pubmed

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts.

MTSS1 PKD2

1.34e-046105220181743
Pubmed

The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway.

EBF3 EBF1

1.34e-046105220621716
Pubmed

Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.

EBF3 EBF1

1.34e-04610529389446
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ADAMTS1 PRSS56 HNRNPM ZBTB9 ZNF362 GIGYF1 BCOR BRWD3 BRD8 ATXN7 CSNK2B VAV1

1.41e-0411161051231753913
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

HNRNPM ZBTB9 SRP72 ZNF362 BCOR THOC2 BRD8 UBN1 PABPC3 CSNK2B KMT2A

1.49e-049541051136373674
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ANKS6 NUMBL EBF3 FAM210A MAML1 SRP68 FAM117B GIGYF1 ZYX MAP3K3 EFHC1 CSNK2B PKD2

1.76e-0413211051327173435
Pubmed

PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions.

PARD6G PARD3B

1.88e-047105212459187
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

EBF3 EBF1

1.88e-047105224786561
Pubmed

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.

RELB KMT2A

1.88e-047105219219072
Pubmed

Gene organization of murine homeobox-containing gene clusters.

HOXB3 HOXB6

1.88e-04710522906328
Pubmed

Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene.

HOXB3 HOXB6

1.88e-04710522463210
Pubmed

Developmental stage-dependent collaboration between the TNF receptor-associated factor 6 and lymphotoxin pathways for B cell follicle organization in secondary lymphoid organs.

MAP3K14 RELB

1.88e-047105217982070
Pubmed

The murine and Drosophila homeobox gene complexes have common features of organization and expression.

HOXB3 HOXB6

1.88e-04710522566383
Pubmed

A novel hook-related protein family and the characterization of hook-related protein 1.

HOOK2 SNX1

1.88e-047105215882442
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP32 ARHGAP30 OPHN1

8.42e-0450673721
GeneFamilyX-linked mental retardation|Angiotensin receptors

THOC2 BRWD3 OPHN1

9.98e-0453673103
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP

MTSS1 FAM117B ZNF362 HOXB3 EFHC1 BRD8 ANO3

1.31e-051971037M9862
CoexpressionGSE17721_CTRL_VS_LPS_12H_BMDC_DN

REPS1 PARG PARD3B SLC26A8 G3BP2 N4BP1 HOOK2

1.40e-051991037M3702
CoexpressionHADDAD_B_LYMPHOCYTE_PROGENITOR

DEPP1 MLXIP ZHX2 FAM171A1 EFHC1 PKD2 KMT2A MAP4K4

1.95e-052901038M939
ToppCelldroplet-Heart-nan-18m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF366 SRP72 FAM117B ZNF362 FAM171A1 SMG8 HOXB6

1.31e-0716810372201ae834b53cbdc085f8f02607fa5b5bd911268
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 EBF3 ZNF366 RELB EBF1 FAM171A1

2.45e-0616610368e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 EBF3 LAMA4 EBF1 LRRC7 ANO3

3.32e-061751036795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 ANKS6 DEPP1 SYNPO SYBU CHST8

3.79e-061791036e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 ANKS6 DEPP1 SYNPO SYBU CHST8

3.79e-0617910369863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 ANKS6 DEPP1 SYNPO SYBU CHST8

3.79e-061791036dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellEndothelial-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PARD6G EBF1 CHST8 FAM171A1 HECTD2

4.04e-0618110364fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCellCOVID-19-Heart-Mito_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF3 ZNF366 PRSS56 SYNPO EBF1 RYR1

5.33e-061901036ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 SOBP LAMA4 EBF1 NAV2 ANO3

5.50e-061911036a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 SOBP LAMA4 EBF1 NAV2 ANO3

5.50e-0619110368f6d592edc32fdb901af30501d4360512334e8c2
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DEPP1 MTSS1 FAM117B SYBU FAM171A1

5.83e-061931036a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 ADAMTS1 LAMA4 ITGB1 ZYX ZNF503

6.95e-06199103636c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGAP32 DYM PARD3B ZHX2 OPHN1

6.95e-06199103694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP27B1 MTSS1 DSCAML1 MAP4K4 ANO3

1.51e-0513410350b1bb6fee8a2d8c27bca6d9cac6b47e85073dbf7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 EBF3 SOBP EBF1 VGLL1

2.59e-0515010351270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 EBF3 SOBP EBF1 VGLL1

2.59e-051501035156118ce1d69522624196410cba18b8354cd0bb4
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF366 MAP3K14 RELB DSCAML1 JRK

3.13e-051561035095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF366 MAP3K14 RELB DSCAML1 JRK

3.13e-05156103529b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD4 ANKS6 HOXB3 NAV2 VGLL1

4.33e-051671035d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

4.71e-051701035fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

4.71e-05170103503044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP32 DNAH3 C2orf81 EFHC1 GAS2L2

4.85e-0517110351854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell356C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF366 MAP3K14 DSCAML1 HOXB3 G3BP2

4.85e-0517110353d60e7ecf25e4b781ba2387671b2aad247fb75ff
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

ZNF366 MAP3K14 SYNPO RELB EBF1

4.85e-051711035ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

LAMA4 PARD6G EBF1 CHST8 FAM171A1

5.12e-051731035dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 EBF3 ZNF366 DEPP1 EBF1

5.26e-05174103518ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 HOXB3 PKD2 NAV2 ANO3

5.41e-0517510351799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related|GW09 / Sample Type, Dataset, Time_group, and Cell type.

EBF3 FAM210A ZBTB9 CHST8

5.94e-0591103425197fde8b9bdaf1e28add695d13aff3ff52d86e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related-Oligodendrocyte/OPC|GW09 / Sample Type, Dataset, Time_group, and Cell type.

EBF3 FAM210A ZBTB9 CHST8

5.94e-05911034ed4a48e5e5f5d8aadbc7b1b8d84a5f6363a08b85
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

THSD4 ADAMTS1 LAMA4 EBF1 MTUS2

6.18e-051801035d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 LAMA4 PARD3B ZNF503 HOXB3

6.34e-051811035fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 DEPP1 LAMA4 PARD6G CHST8

6.51e-05182103541b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

6.51e-05182103544764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 DEPP1 LAMA4 PARD6G CHST8

6.51e-0518210355e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 DEPP1 LAMA4 PARD6G CHST8

6.51e-051821035b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

6.51e-051821035d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 EBF1 NAV2 LRRC7 ANO3

6.86e-051841035e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF366 PIEZO1 SRP72 ATG2A BRD8

6.86e-051841035af6522586d012e91241f3e06c60f9d1881e95646
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 ADAMTS1 SOBP PARD6G EBF1

6.86e-051841035327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K14 ARHGAP30 RELB DSCAML1 MAP4K4

7.04e-05185103519fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELB MLXIP ZHX2 UBN1 MAP4K4

7.04e-051851035eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

ADAMTS1 LAMA4 PARD6G EBF1 FAM171A1

7.40e-0518710351e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

7.78e-05189103571397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

7.78e-0518910354eea4759520c312bd17a681034d8074e47093d2b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 C2orf81 EFHC1 GAS2L2 FOXI1

7.78e-051891035cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

MTSS1 PARD6G RYR1 STARD5 N4BP1

7.78e-051891035533c302df467d13ab639232daf4f8cafb808260b
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 PIEZO1 CITED4 ANO3 FOXI1

7.78e-05189103527e5d706f10a6221f314faf642eede15deab3165
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS1 ZNF366 DEPP1 SYNPO EBF1

7.98e-0519010351519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DSCAML1 FAM171A1 HOXB3 NAV2

7.98e-0519010353dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.18e-05191103539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

EBF3 PARD6G EBF1 NAV2 MAP4K4

8.18e-05191103578ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 PARD3B PKD2 NAV2 ANO3

8.18e-0519110356688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.18e-051911035ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.38e-051921035bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.38e-0519210355105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEPP1 MTSS1 FAM117B SYBU FAM171A1

8.38e-051921035c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PRSS56 DEPP1 MTSS1 MAP3K14 RELB

8.38e-0519210352c69f3f388b69fb1c1968c923cdbab90658883dd
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

THSD4 GDF5 EBF3 SYNPO EBF1

8.38e-051921035d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PIEZO1 GIGYF1 BRD8 KMT2A ESPL1

8.38e-0519210359cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS56 DEPP1 MTSS1 MAP3K14 RELB

8.38e-051921035d5a7b546ebfb2e757dd9c64cb1b651f6ed0e0fc7
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 PARD3B PKD2 NAV2 ANO3

8.38e-05192103599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ZNF366 DEPP1 SYNPO EBF1

8.38e-05192103556b021c297a21dff357531f21e2464f85186106d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.38e-0519210350ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF3 MTSS1 LAMA4 EBF1 C22orf31

8.59e-051931035549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF366 DEPP1 MAP3K14 SYNPO RELB

8.59e-0519310357426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF366 DEPP1 MAP3K14 SYNPO RELB

8.59e-051931035a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ZNF366 MTSS1 SYNPO EBF1

8.59e-0519310351f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

DEPP1 MAP3K14 SYNPO RELB NAV2

8.80e-05194103530f683725cb13ae32ef6846618801ec78e12397d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA4 EBF1 NAV2 ANO3

8.80e-051941035e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 SYNPO ZNF503 FAM171A1 FEZF1

8.80e-051941035e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

SOBP PARD3B EBF1 OPHN1 NAV2

8.80e-051941035234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 SYNPO ZNF503 FAM171A1 FEZF1

8.80e-0519410354b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

THSD4 LAMA4 PARD6G PARD3B EBF1

9.01e-051951035e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

SOBP PARD3B EBF1 OPHN1 NAV2

9.01e-051951035a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 EBF3 ZNF366 EBF1 FAM171A1

9.01e-051951035d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS1 LAMA4 EBF1 NAV2 ANO3

9.01e-051951035aa0add081881d349099d12efca5cdee098038d4e
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 PARD3B ZHX2 OPHN1 NAV2

9.23e-051961035ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ADAMTS1 LAMA4 EBF1 ANO3

9.23e-0519610353a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ADAMTS1 LAMA4 EBF1 ANO3

9.23e-051961035bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 PARD3B EBF1 PKD2 NAV2

9.23e-0519610357d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOVID-19-Myeloid-Migratory_DC|COVID-19 / Condition, Lineage and Cell class

ZNF366 DEPP1 MAP3K14 SYNPO RELB

9.46e-051971035b6d6cdae33753c1e38394f1f879e00b87f9c0496
ToppCellBronchial_Biopsy-Endothelial-Endothelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ADAMTS1 EBF3 ZNF366 LAMA4 EBF1

9.69e-051981035d4a4e5c358d26d09ff27541ce49d0db75c1cd08e
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGAP32 PARD3B OPHN1 NAV2

9.69e-0519810351996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 PARD3B EBF1 PKD2 NAV2

9.69e-0519810358f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellBronchial_Biopsy-Endothelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ADAMTS1 EBF3 ZNF366 LAMA4 EBF1

9.69e-051981035ec80b05b8a1800c341b5741bf3e57213308398a7
ToppCellBronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

THSD4 SYNPO HOXB6 LRRC7 ESPL1

9.69e-051981035dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCellstromal_cell|World / Lineage and Cell class

ADAMTS1 EBF3 DEPP1 LAMA4 NAV2

9.92e-051991035507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

ADAMTS1 EBF3 DEPP1 LAMA4 NAV2

9.92e-05199103574262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCellBAL-Severe-cDC_10|Severe / Compartment, Disease Groups and Clusters

ZNF366 DEPP1 MAP3K14 SYNPO RELB

9.92e-05199103554bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 MTSS1 LAMA4 EBF1 LRRC7

9.92e-0519910353835452e4848d7f7dd8651c17b746b271ef39688
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 MTSS1 LAMA4 EBF1 LRRC7

9.92e-0519910359c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

ZNF366 LAMA4 ITGB1 ZNF503 FAM171A1

1.02e-042001035eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PRSS56 HOXB3 TRIM67 NAV2 MTUS2

1.02e-042001035a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 LAMA4 EBF1 HOXB3 PKD2

1.02e-042001035cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

THSD4 ADAMTS1 LAMA4 HECTD2 PKD2

1.02e-04200103508bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

THSD4 EBF3 EBF1 CHST8 FEZF1

1.02e-0420010356f3fe94107fa2a2ded4888780b36700cce48adb7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

THSD4 ADAMTS1 LAMA4 HECTD2 PKD2

1.02e-042001035dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate|10w / Sample Type, Dataset, Time_group, and Cell type.

PRSS56 ZBTB9 TBC1D22B ZNF503 ESPL1

1.02e-042001035e5a8647c47a49c8c90c78d681193946de103d8ff
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

LAMA4 RYR1 STARD5 KLHDC1 CITED4

1.02e-0420010354b937b1d0179d1d0e51931f35720e205d460a07e
ToppCell(01)_IL1RL1+|World / shred by cell type by condition

ADAMTS1 ITGB1 ZYX CITED4 MAP4K4

1.02e-042001035501420901bf3ec1b050e0d14596a9f9f3fdfc928
DiseaseImpulsive Petit Mal Epilepsy

EFHC1 JRK

6.93e-0541012C4553298
DiseaseJuvenile Myoclonic Epilepsy of Janz

EFHC1 JRK

6.93e-0541012C4551857
DiseaseMyoclonic Epilepsy, Adolescent

EFHC1 JRK

6.93e-0541012C4552768
DiseaseMyoclonic Epilepsy, Juvenile, 1

EFHC1 JRK

6.93e-0541012C4553087
DiseasePolycystic kidney disease, type 2

ANKS6 PKD2

2.41e-0471012C2751306
DiseaseChildhood Absence Epilepsy

EFHC1 JRK

2.41e-0471012C4281785
DiseaseEpilepsy, Minor

EFHC1 JRK

2.41e-0471012C4552765
DiseaseAbsence Epilepsy

EFHC1 JRK

2.41e-0471012C0014553
DiseaseAkinetic Petit Mal

EFHC1 JRK

2.41e-0471012C0001890
DiseaseEpilepsy, Absence, Atypical

EFHC1 JRK

2.41e-0471012C0751124
DiseaseAbsence Seizure Disorder

EFHC1 JRK

2.41e-0471012C4553705
DiseaseJuvenile Absence Epilepsy

EFHC1 JRK

2.41e-0471012C4317339
Diseaseinterleukin 4 measurement

LRIG2 TRIM67 MTUS2

2.56e-04361013EFO_0008184
DiseaseJuvenile Myoclonic Epilepsy

EFHC1 JRK

3.20e-0481012C0270853
DiseasePolycystic Kidney, Type 1 Autosomal Dominant Disease

ANKS6 PKD2

3.20e-0481012C0887850
DiseasePolycystic Kidney, Autosomal Dominant

ANKS6 PKD2

4.11e-0491012C0085413
Diseasepolycystic kidney disease (implicated_via_orthology)

ANKS6 PKD2

1.03e-03141012DOID:0080322 (implicated_via_orthology)
Diseasespine bone size

GDF5 DYM

1.71e-03181012EFO_0004508

Protein segments in the cluster

PeptideGeneStartEntry
KERRPLDAHPPQPGV

FAM210A

66

Q96ND0
FGPQELAKPPKHFNP

CXorf66

231

Q5JRM2
HPIQQERDKPVPLPA

BRD8

461

Q9H0E9
KATAQGQPRPPHRPA

DEPP1

56

Q9NTK1
GHRVQHQPQKRPPAP

CD2

301

P06729
HQPQKRPPAPSGTQV

CD2

306

P06729
PRVQPKPPHGAAENS

CD2

331

P06729
HRGRPPELPVNYVKP

BRWD3

126

Q6RI45
PPFLVDVDGNPHPTK

BRWD3

586

Q6RI45
FPGRKQPGVHEEPVL

C22orf31

266

O95567
EPPKPSVEPALQQHR

BCOR

836

Q6W2J9
PQPAFRHQGPEPLLV

FAM90A10

211

A6NDY2
APPVDVHQPPAFLHK

ATG2A

211

Q2TAZ0
IVNPITGKPEPHQPS

ANO3

526

Q9BYT9
VPPAAAFQPGHKRTP

NUMBL

396

Q9Y6R0
AAARNGFPPKPDPQA

MTUS2

976

Q5JR59
PGPQPHLVITEQPKQ

RELB

121

Q01201
AAPGEKPPAPLQFHL

ADAMTS1

171

Q9UHI8
RDKLPQPVQPDPVSH

ITGB1

676

P05556
KPPQHPKLPIQRSGE

OPHN1

631

O60890
PQPAFRHQGPEPLLV

FAM90A7

211

A6NKC0
FEVQPEPGAAPVRPK

CYP27B1

476

O15528
AGKHRQPPAATAPAP

MAML1

71

Q92585
PPAPQHKGPFRQDVP

PARD3B

1146

Q8TEW8
HKGPFRQDVPPSPPQ

PARD3B

1151

Q8TEW8
PPQQERSKPSFHAPE

MAP4K4

541

O95819
PAAQHRLPQPPVGKG

PTPRN

151

Q16849
YPPVQEHQQKEPRAP

FAM171A1

766

Q5VUB5
PKPGHPPQTRQATAR

GDF5

106

P43026
GERQLHKQPPPREPA

GIGYF1

781

O75420
KRIPPPFQHNPEYVQ

LRRC7

1046

Q96NW7
PKQRPAAGAPPELHS

HOOK2

616

Q96ED9
GDFFPPERPQQLPHG

HNRNPM

286

P52272
HLVFPNIKNVREPPP

HECTD2

81

Q5U5R9
RNFINPPVPLQGPHA

JRK

341

O75564
PGPKPSIPEEHRQAI

MTSS1

676

O43312
PKDAHVQFRVPPSSP

PARG

41

Q86W56
RGPGHPPLPDKFQFE

PDE4A

696

P27815
ARYLEPGIPPEQPHQ

EPS8L3

181

Q8TE67
QPEREPQPGHKVERP

OTUD7A

86

Q8TE49
GSLQHAQPPPQPRKK

PDPK2P

36

Q6A1A2
HKVQGVVPVPERPPE

ARHGAP32

1336

A7KAX9
KELIRHPDSQQPPQP

ATXN7

396

O15265
ARPHPFQNKPSAIRP

PABPC3

436

Q9H361
GPAERARHQPPQPKA

PAIP1

36

Q9H074
ARHQPPQPKAPGFLQ

PAIP1

41

Q9H074
FVGPPAPRVLQNFHP

PARD6G

276

Q9BYG4
SGADEQPPFHPEPRK

HOXB6

91

P17509
NPPAPPTFHQPQKFA

MLXIP

461

Q9HAP2
TPKPPDRIRQAGPHV

ESPL1

1346

Q14674
LAAPPHPGPAFQRSK

DNAH3

11

Q8TD57
NFIRQEKPPPPGAHV

DYM

221

Q7RTS9
EKPPPPGAHVFPQQS

DYM

226

Q7RTS9
VKGPPQGPRLHIDIP

DSCAML1

1646

Q8TD84
KPPAPPVQHEVRVQD

GAS2L2

286

Q8NHY3
PPHVKAPVSQPRVEA

G3BP2

266

Q9UN86
QLIPQDIPDGHRAPP

FAM117B

366

Q6P1L5
PPPQGRIQEAPKLTH

HOXB3

416

P14651
VNKDKGRPSHQPPLP

ANKS6

421

Q68DC2
FQRLQKVIPRHPGDP

EBF1

356

Q9UH73
HPEYRPKRPANQFVP

CSNK2B

171

P67870
QPKQAPPADFIPAHV

EFHC1

76

Q5JVL4
PEIKGGVPPQPRAAH

KLHDC1

186

Q8N7A1
RFHKPEEANEPPLNP

KMT2A

3746

Q03164
FPPVEQHPIQTGAPK

C2orf81

566

A6NN90
FHPQGVPSPQRPSFE

FOXI1

36

Q12951
QKVIPRHPGDPERLP

EBF3

361

Q9H4W6
RAPGPQAHPVPKDAR

CAPN9

6

O14815
PNGKPERCLRFVHPP

SLC22A8

66

Q8TCC7
ITAHNERKPNPPPGL

RYR1

4751

P21817
SPPPGYVPERQQHIA

MAP3K3

176

Q99759
EVPVNRILPHPKFDP

PRSS56

171

P0CW18
ERKGHHPLNPQVPPA

PRSS56

586

P0CW18
KIHVAPANPCPRPGR

ARHGAP30

956

Q7Z6I6
GPLNPKPIDHREPVF

LAMA4

1756

Q16363
RGEYKEPRHPPPNQA

MAP3K14

666

Q99558
KVEPPRNQDPAHPDK

SMG8

276

Q8ND04
QQAGVVAHPPAVPPR

REPS1

576

Q96D71
QPVYGAQHPPLDPRL

TBC1D22B

21

Q9NU19
QKHPSIEDGPPFVEP

GET4

221

Q7L5D6
RRHFGEKAPAPQPPS

SYNPO

506

Q8N3V7
EPNPKSRPRAHTFPQ

SLC26A8

911

Q96RN1
PEPKALPVPHFLQGA

FEZF1

41

A0PJY2
AAPILHVPPARAGPQ

NAV2

21

Q8IVL1
IIPPRHQKPAGAPAT

SRP72

641

O76094
QANLVHFPPGFQPIP

SRP68

571

Q9UHB9
FPAVPPPAAGIAHLQ

CITED4

76

Q96RK1
QVPGIKFNIRPRQPH

CHST8

41

Q9H2A9
GPRLAAHFPAQRPPQ

CLPP

21

Q16740
HKQQPEAPEPAGQRP

CLCN1

751

P35523
SRGPFAKHRLVQPPP

TRIM67

241

Q6ZTA4
IPENEFHHKDPPPRN

THOC2

1181

Q8NI27
HSQNGFIVPPPPEKS

SNX1

201

Q13596
QDKPPRENGHVPFHP

SAMD4B

191

Q5PRF9
NHGVRPPNPEQYLTP

SYBU

256

Q9NX95
IPIPHVSDSKPPNGF

SOBP

541

A7XYQ1
PCNRVKPYVHGPPQD

VAV1

651

P15498
LCPPKPGFVRGFNHP

STARD5

141

Q9NSY2
RVQPQQPGDAKRPPA

PKD2

6

Q13563
TEKPPQGEVAFPHHP

ZNF446

371

Q9NWS9
QPQRVSGVFPRPHGP

ZBTB9

236

Q96C00
PPQFLPHGVALDPTK

ZNF503

371

Q96F45
TPQAAPEPKRPHIAQ

ZHX2

411

Q9Y6X8
PPRAHVSPQEAPLGQ

nan

71

Q6ZR54
PVASRGKAPQRHPFP

ZNF366

31

Q8N895
HGPQVAVPVPGPQVK

UBN1

791

Q9NPG3
FGPVVAPKPKVNPFR

ZYX

26

Q15942
PKLQQVPGLHPQAVP

ZNF362

86

Q5T0B9
EPLRGEPNPVPNFIH

PIEZO1

1136

Q92508
QVPPHRRPGEPFNGQ

THSD4

536

Q6ZMP0
PARHLVPEPQPDGKR

VGLL1

151

Q99990
NRELGLPHPPFSQQP

LRIG2

1001

O94898
PRVPLFPENGLHQQP

N4BP1

516

O75113