Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF3585

MICAL3 EHBP1L1

7.97e-057372PF12130
DomainDUF3585

MICAL3 EHBP1L1

7.97e-057372IPR022735
Domainp53-like_TF_DNA-bd

EOMES RUNX3 NFAT5

1.57e-0453373IPR008967
DomainCH

NAV2 MICAL3 EHBP1L1

2.87e-0465373SM00033
DomainCH

NAV2 MICAL3 EHBP1L1

3.58e-0470373PF00307
Domain-

NAV2 MICAL3 EHBP1L1

3.73e-04713731.10.418.10
DomainCH

NAV2 MICAL3 EHBP1L1

4.05e-0473373PS50021
DomainCH-domain

NAV2 MICAL3 EHBP1L1

4.38e-0475373IPR001715
DomainDEAD_ATP_HELICASE

DDX4 EIF4A1

1.71e-0331372PS00039
DomainRNA-helicase_DEAD-box_CS

DDX4 EIF4A1

1.94e-0333372IPR000629
DomainRNA_helicase_DEAD_Q_motif

DDX4 EIF4A1

2.43e-0337372IPR014014
DomainQ_MOTIF

DDX4 EIF4A1

2.43e-0337372PS51195
DomainDEAD

DDX4 EIF4A1

9.19e-0373372PF00270
DomainDEAD/DEAH_box_helicase_dom

DDX4 EIF4A1

9.19e-0373372IPR011545
DomainHelicase_C

DDX4 EIF4A1

1.90e-02107372PF00271
DomainHELICc

DDX4 EIF4A1

1.90e-02107372SM00490
DomainHelicase_C

DDX4 EIF4A1

1.93e-02108372IPR001650
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MICAL3 RNF169 CTIF KAZN PLEKHG3 PALLD

1.26e-0549337615368895
Pubmed

Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice.

DDX4 BMP15

1.65e-05637227050391
Pubmed

A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.

EOMES RUNX3

1.65e-05637225129370
Pubmed

The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma.

EOMES RUNX3

3.07e-05837220399120
Pubmed

Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice.

DDX4 EIF4A1

3.07e-05837233351795
Pubmed

The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.

EOMES DDX4

3.07e-05837233542216
Pubmed

Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates.

EOMES CELF2

3.95e-05937234107259
Pubmed

Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration.

MYOD1 ELMO1

7.22e-051237236400788
Pubmed

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.

EOMES DDX4

7.22e-051237220823249
Pubmed

Compromised cell competition exhausts neural stem cells pool.

EOMES ELMO1

8.53e-051337239010274
Pubmed

Three-dimensional molecular architecture of mouse organogenesis.

EOMES CELF2 DDX4

1.67e-0410037337524711
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NAV2 RNF169 ZNF148 TRIM29 PALLD

1.85e-0450337516964243
Pubmed

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.

RUNX3 DDX4

2.28e-042137231712577
Pubmed

Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.

EHBP1L1 PALLD

2.28e-042137220708005
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

KAZN ZNF148 NFAT5 CAVIN2 EIF4A1 U2SURP

2.50e-0484737635850772
Pubmed

Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice.

MYOD1 DDX4

2.51e-042237225224227
Pubmed

Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon.

EOMES OPRM1

2.51e-042237211124115
Pubmed

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.

FCHSD2 RUNX3

2.51e-042237223266558
Pubmed

Gene network analysis in a pediatric cohort identifies novel lung function genes.

MICAL3 CTIF

2.99e-042437224023788
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

KIAA1549 NFAT5 U2SURP

3.61e-0413037312421765
Pubmed

A census of human transcription factors: function, expression and evolution.

EOMES KIAA1549 ZNF148 RUNX3 NFAT5 MYOD1

3.63e-0490837619274049
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ZNF148 RUNX3 NFAT5 EIF4A1 U2SURP

3.64e-0458337529844126
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

ZNF148 NFAT5

4.09e-042837229365100
Pubmed

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.

EOMES DDX4

4.09e-042837223473982
Pubmed

Tagging genes with cassette-exchange sites.

NAV2 CLASP2 RNF169 ZNF148

4.35e-0433537415741177
Pubmed

ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.

DDX4 BMP15

5.02e-043137231657143
Pubmed

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

EOMES DDX4

6.05e-043437220007774
Pubmed

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.

CELF2 EIF4A1

6.41e-043537237758766
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

MICAL3 CLASP2 PALLD EIF4A1 U2SURP

6.84e-0467037522990118
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

EOMES CLASP2

7.16e-043737227565344
Pubmed

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis.

EOMES DDX4

7.56e-043837234059773
Pubmed

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.

EOMES MYOD1

8.80e-044137222147266
Pubmed

SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.

MYOD1 DDX4

8.80e-044137228118982
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RNF169 PALLD U2SURP

9.92e-0418437332908313
Cytoband11q13.4

FCHSD2 RNF169

1.69e-037537211q13.4
GeneFamilyDEAD-box helicases

DDX4 EIF4A1

1.41e-0342242499
CoexpressionGSE17721_CTRL_VS_POLYIC_6H_BMDC_DN

CLASP2 PALLD DDX4 ELMO1 U2SURP

8.58e-06199375M3716
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

MICAL3 RUNX3 CELF2 PALLD ELMO1

2.40e-07164375519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAV2 NFKBIZ TNFAIP8L3 PALLD

9.51e-06161374b19f82dd98a3064581793711bb70373f18abecd9
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|367C / Donor, Lineage, Cell class and subclass (all cells)

EOMES RUNX3 PLEKHG3 OPRM1

9.75e-0616237459c0dcb5b51c1803660aeec51b60deceeeaeea66
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ZC2HC1C RUNX3 PLEKHG3 PALLD

1.21e-0517137404c811817cfec45af5f2891793106cc7ddb0300e
ToppCellCOVID-matDC-|COVID / Condition, Cell_class and T cell subcluster

NAV2 KAZN TNFAIP8L3 CAVIN2

1.32e-05175374db5e170411dfa62074c4b8311bb8c589d1c4279b
ToppCellCOVID-matDC|COVID / Condition, Cell_class and T cell subcluster

NAV2 KAZN TNFAIP8L3 CAVIN2

1.32e-05175374e2b638109c9ffd10430e6e134035622b7605ce23
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARD6 CFAP54 TNFAIP8L3 CAVIN2

1.54e-051823748d8f28bd43108b2fb3a6c2a3d77a897853d440a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CTIF CFAP54 KAZN PALLD

1.64e-0518537434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellP03|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAV2 NFKBIZ CELF2 PALLD

1.64e-05185374a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CTIF CFAP54 KAZN PALLD

1.64e-051853748816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

SLC5A5 NAV2 PALLD CAVIN2

1.86e-051913743457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAV2 MICAL3 CELF2 PALLD

1.90e-051923742802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCHSD2 CELF2 NFAT5 ELMO1

1.94e-05193374779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2 ELMO1

1.94e-0519337412f1333f11e6c262954ad7912d8fd2962ab06d25
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MICAL3 KAZN PALLD ELMO1

1.98e-0519437435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2 ELMO1

1.98e-05194374633fe72cc8a489abde12428e326478409ca03263
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2 ELMO1

1.98e-0519437487a86df0b542f287b0b20f4a4b1a37002271671d
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

NAV2 NFKBIZ KAZN CELF2

2.02e-05195374a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

NAV2 FCHSD2 EHBP1L1 TNFAIP8L3

2.02e-051953745562665dd3beb70e2358aa32611a337bef5731c1
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

NAV2 NFKBIZ KAZN CELF2

2.06e-05196374e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 RUNX3 CELF2 ELMO1

2.10e-051973748af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 RUNX3 CELF2 ELMO1

2.10e-05197374c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCHSD2 MICAL3 CFAP54 ELMO1

2.10e-051973740f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell3'_v3-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 NFKBIZ PALLD CAVIN2

2.14e-05198374920d2e6603a06c2e8dcb6be127202d222c662bca
ToppCell3'_v3-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 NFKBIZ PALLD CAVIN2

2.14e-05198374807e3ed34739eca159dd0970f884b073e588c649
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EOMES RUNX3 CELF2 OPRM1

2.19e-0519937409e0b45529fa9d5fc86da1747b3fb3a238a09aa6
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

EOMES RUNX3 PLEKHG3 PALLD

2.19e-05199374df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

EOMES RUNX3 PLEKHG3 PALLD

2.19e-05199374e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

EOMES RUNX3 PLEKHG3 PALLD

2.19e-05199374ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

EOMES RUNX3 PLEKHG3 PALLD

2.19e-051993745f914962e2572b0c6372465b81b7496fa663d93c
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

EOMES RUNX3 PLEKHG3 PALLD

2.23e-052003742281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EOMES RUNX3 CELF2 OPRM1

2.23e-0520037413d8c5d65d7f900979319433e7044efa6d06de20
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Nnat_(Presubiculum,_Col5a2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

XKR7 ITPRID1 MYOD1

2.82e-05713733f7ab70a5451043019f6e56c16ab95182ff44a15
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Nnat_(Presubiculum,_Col5a2+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

XKR7 ITPRID1 MYOD1

2.82e-0571373f0af76191cb0e29abf6e7d1a6f5a0df1ad837ce7
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES RUNX3 DDX4

2.21e-04142373c2a3cd9998fd9a8e6b2665347ca5c32511776488
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES RUNX3 DDX4

2.35e-0414537323a1ee986774725a9f5a9154fbbd023031fb0452
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

XKR7 C16orf90 MYOD1

2.40e-04146373c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EOMES RUNX3 OPRM1

2.55e-04149373f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1549 NFKBIZ CFAP54

2.70e-04152373faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1549 NFKBIZ CFAP54

2.70e-04152373519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RUNX3 CELF2

2.97e-04157373170197b76620df31495f1247f365da382b2d8045
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RUNX3 CARF

2.97e-04157373a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RUNX3 CELF2

2.97e-04157373c21520301cc0d5d4b1cc4b8ec735f9adb698e768
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RUNX3 CELF2

3.02e-041583737274f020c0ecf216da4b6689c62bc5f49c29b6f3
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIAA1549 MICAL3 CTIF

3.02e-0415837374aa4f75307575ac3b2b1aa9f727753692f88742
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A5 CTIF MYOD1

3.02e-04158373f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A5 CTIF MYOD1

3.02e-041583738c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

EOMES RUNX3 PLEKHG3

3.08e-041593739e2067f0d76769717f7048dab505fadd36bbb83e
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TNFAIP8L3 RUNX3 CAVIN2

3.14e-041603738aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|367C / Donor, Lineage, Cell class and subclass (all cells)

EOMES RUNX3 PLEKHG3

3.20e-04161373f7dc1e3326ab22f2eb1e94b632469a0682a3289c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 EHBP1L1 PALLD

3.37e-04164373b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RUNX3 PLEKHG3

3.37e-0416437384a1808bc6f501218ac2a5a05eb188a07ccd3890
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NAV2 FCHSD2 MICAL3

3.43e-041653738003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EHBP1L1 RUNX3 CARF

3.43e-041653731c630f9ecde2e0243922a2be4b1ab5adcfcb0893
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

FCHSD2 MICAL3 ELMO1

3.62e-04168373a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

3.62e-04168373318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

3.62e-0416837375b3998aff704a77895ee3723813d8a3819b7cec
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MICAL3 CFAP54 KAZN

3.62e-04168373a086c306be430adf0632ba53e98cd8014d2de330
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

NAV2 KAZN CELF2

3.68e-041693736373562ab3b1765060212a6a53d6543e7e942e80
ToppCelldroplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1L1 RUNX3 CARF

3.75e-04170373545c755b057871b7a22221a049a63a61713dad1d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 KAZN PALLD

3.81e-04171373972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 KAZN PALLD

3.81e-041713732a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C16orf90 TP53AIP1 TRIM29

3.88e-04172373e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EOMES RUNX3 OPRM1

3.88e-041723732b0333c21b7472194a7b9feb3de121da3340fc5b
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A5 CFAP54 PLEKHG3

3.94e-04173373d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 C16orf90 DDX4

3.94e-0417337327ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A5 CFAP54 PLEKHG3

3.94e-041733733c852ffe22f4a5b632463086b08c669310684e80
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL3 NFAT5 CAVIN2

3.94e-04173373fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 PALLD CAVIN2

4.01e-04174373e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

NAV2 PALLD ELMO1

4.01e-04174373430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 PALLD CAVIN2

4.01e-0417437305525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.01e-0417437347e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.01e-04174373a92c745d20633909db0f08effa13fc738fda79a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 KAZN TNFAIP8L3

4.08e-04175373910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIAA1549 FCHSD2 C16orf90

4.08e-04175373aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.08e-041753732f43883d7c89f09b0579a390a7431f1f9b832582
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 KAZN TNFAIP8L3

4.08e-04175373f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.08e-04175373da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFKBIZ RNF169 PALLD

4.08e-04175373cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 CELF2 ELMO1

4.22e-04177373b07e6139618d888a9fd7cf43cad0d86a3f63e09e
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

TP53AIP1 TRIM29 PLEKHG3

4.22e-04177373a0c7d08469c513cecf87777c19876884f1511570
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUNX3 DDX4 OPRM1

4.22e-0417737389e9ac601bc80bd33141da84056189950e563a1e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 CELF2 ELMO1

4.22e-041773736376ec12322c04d5d37ec2fdc376700464cbc7fb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 CELF2 ELMO1

4.29e-0417837324e8c62060455159235985f456af0c5023a7f3f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 CELF2 ELMO1

4.29e-041783734f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

KIAA1549 RUNX3 ELMO1

4.29e-0417837334ec499d03cc198cfefa19a724d4c81974052f65
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MICAL3 CFAP54 KAZN

4.29e-04178373544379f5a6145429762258d426b876bb36c112f5
ToppCellfacs|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLASP2 TRIM29 PALLD

4.36e-041793738001db3044e8657980e24422377c4fdb0d7b323e
ToppCellnormal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|normal_Lymph_Node / Location, Cell class and cell subclass

EOMES KAZN RUNX3

4.36e-041793733dc929a10381b7d86650c6cd8f354892fe1d93e7
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 XKR7 RUNX3

4.36e-041793736f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.43e-04180373bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

FCHSD2 CELF2 ELMO1

4.43e-041803735650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

NFKBIZ PALLD CAVIN2

4.43e-04180373adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 CELF2 ELMO1

4.43e-0418037365c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EOMES RUNX3 CELF2

4.43e-04180373c62417f205bcbf3b212ae177f63562ec6467c855
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

NAV2 KAZN CELF2

4.50e-041813732b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EOMES RUNX3 TRIM29

4.50e-041813739c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCellnormal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

EOMES KAZN RUNX3

4.50e-041813737e12030965881b023f0d3d27d934fa648e2cc523
ToppCellCOVID-19-kidney-Mito-rich_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

RUNX3 CELF2 ELMO1

4.50e-041813738448c2ad560cfd48bfe9dc1dd3a64373e6a622dd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 RUNX3 ELMO1

4.50e-041813735a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
DrugEstropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LMF1 EHBP1L1 KAZN TRIM29 PLEKHG3

1.53e-051953756808_UP
DrugPirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A

CTIF LMF1 KAZN NFAT5 PLEKHG3

1.53e-051953752234_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A

SLC5A5 ZC2HC1C CTIF EHBP1L1 OPRM1

1.60e-051973755242_UP
Drugprednisolone; Up 200; 1uM; MCF7; HG-U133A

CLASP2 CTIF LMF1 NFAT5 PLEKHG3

1.68e-05199375265_UP
Druglevo-dromoran tartrate

TNFAIP8L3 DDX4 CAVIN2 OPRM1

1.91e-0598374CID000003918
Drugnalorphine-epoxide

DDX4 OPRM1

2.56e-055372CID003086440
Diseasecarotid artery intima media thickness

NAV2 CTIF KAZN PALLD MYOD1 ELMO1

1.90e-05450376EFO_0007117
Diseaseadverse effect, response to xenobiotic stimulus

NAV2 RUNX3 CELF2

5.62e-0559373EFO_0009658, GO_0009410
Diseasepsoriasis vulgaris

NFKBIZ RUNX3 ELMO1

6.21e-0561373EFO_1001494
Diseaseresponse to carboplatin, methylcobalamin deficiency type cblE, response to antineoplastic agent

KAZN ELMO1

1.00e-0412372GO_0097327, GO_0097328, MONDO_0009354
DiseaseGastro-enteropancreatic neuroendocrine tumor

EOMES RUNX3

1.59e-0415372C2930967
DiseaseToxic Epidermal Necrolysis

CELF2 ELMO1

6.08e-0429372C0014518
DiseaseMycoplasma-Induced Stevens-Johnson Syndrome

CELF2 ELMO1

6.08e-0429372C3658301
DiseaseStevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

CELF2 ELMO1

6.08e-0429372C3658302
DiseaseDrug-Induced Stevens Johnson Syndrome

CELF2 ELMO1

6.08e-0429372C1274933
DiseaseStevens-Johnson Syndrome

CELF2 ELMO1

6.51e-0430372C0038325
Diseaseshoulder impingement syndrome

CELF2 ELMO1

9.38e-0436372EFO_1001178
Diseasecholesteryl ester 18:3 measurement

NAV2 ELMO1

1.16e-0340372EFO_0010346
Diseaseurinary albumin to creatinine ratio

KAZN TRIM29 CELF2

1.47e-03179373EFO_0007778
Diseasemultiple sclerosis symptom measurement

CTIF ITPRID1

1.53e-0346372EFO_0803536
Diseasetotal blood protein measurement

EOMES MICAL3 EHBP1L1 RUNX3

2.35e-03449374EFO_0004536
Diseaseblood osmolality measurement

NAV2 NFAT5

2.42e-0358372EFO_0007967
DiseaseMalignant Glioma

SLC5A5 TRIM29

3.50e-0370372C0555198
Diseasemixed gliomas

SLC5A5 TRIM29

3.50e-0370372C0259783
Diseasenephrotic syndrome

RUNX3 ELMO1

3.60e-0371372EFO_0004255
Diseasealbumin:globulin ratio measurement

FCHSD2 RUNX3

3.80e-0373372EFO_0005128
Diseasepsoriasis, type 2 diabetes mellitus

NFKBIZ RUNX3

4.01e-0375372EFO_0000676, MONDO_0005148
DiseaseHodgkins lymphoma

EOMES MYOD1

4.77e-0382372EFO_0000183
Diseasepsoriasis

ITPRID1 RUNX3 ELMO1

4.82e-03273373EFO_0000676
Diseasethalamus volume

NAV2 NFAT5

5.12e-0385372EFO_0006935
Diseasepsoriatic arthritis

NFKBIZ RUNX3

5.35e-0387372EFO_0003778
DiseaseGlioma

SLC5A5 TRIM29

5.35e-0387372C0017638
Diseaseankylosing spondylitis

EOMES RUNX3

5.84e-0391372EFO_0003898
Diseaseserum albumin measurement

MICAL3 EHBP1L1 ZNF148 EIF4A1

6.27e-03592374EFO_0004535

Protein segments in the cluster

PeptideGeneStartEntry
ASAGAPAAMLSDTDA

EOMES

71

O95936
ASTPNSTAGAAMNSL

CELF2

321

O95319
MAAQGSPSSSPSDDS

CFAP54

1

Q96N23
AFDAESEPNNSSGSM

ELMO1

331

Q92556
MENSSAASASSEAGS

CTIF

1

O43310
GDNFNRTPASSSEMD

DDX4

31

Q9NQI0
MGDAASQSPPESSAA

KIAA1549

901

Q9HCM3
MDSSAAPTNASNCTD

OPRM1

1

P35372
EERMAPASESSASGA

MICAL3

1051

Q7RTP6
ASAAGDSAATNMENP

KAZN

56

Q674X7
ASDSSNTSLPFSNMG

NFKBIZ

391

Q9BYH8
ESDGPDSKSRASMSF

ITPRID1

471

Q6ZRS4
SSEGDSSKPSLMSNA

BMP15

166

O95972
MDSRDSSFGQNDSPT

CARF

31

Q8N187
MSASQDSRSRDNGPD

EIF4A1

1

P60842
DSDASSPRSNCSDGM

MYOD1

196

P15172
RNSSSFSMDDPDAGA

EHBP1L1

1291

Q8N3D4
ADASSAPSSSSMGGA

NFAT5

66

O94916
ASRSAPAMQSSGSFN

PALLD

716

Q8WX93
QSMGASSNSEDAFSP

CARD6

106

Q9BX69
PRDSLGSSASSSSMD

C16orf90

126

A8MZG2
DNMDVFDDSSSSPSG

FCHSD2

451

O94868
AEKATSRGSNSGMDS

CAVIN2

356

O95810
SSAASVAAGNLMNPS

RUNX3

366

Q13761
MEAADASRSNGSSPE

TRIM29

1

Q14134
MGSSSEASFRSAQAS

TP53AIP1

1

Q9HCN2
SGSSCDSRSAMEEPS

PLEKHG3

26

A1L390
MSDNAPASLESGSSS

NAV2

346

Q8IVL1
MAAAGPSTRASSAAA

RNF169

1

Q8NCN4
SSDAHMDASGPSDSD

U2SURP

26

O15042
MSDPRAGGDATDSSQ

CLASP2

981

O75122
DAQPAARSMDSDSGE

TNFAIP8L3

81

Q5GJ75
MAAKSDGAAASASPD

XKR7

1

Q5GH72
ANDSSRAPSSGMDAS

SLC5A5

501

Q92911
RNSSLSMAPDSSGSS

ZC2HC1C

366

Q53FD0
DNRAGMTSSPDATTG

ZNF148

776

Q9UQR1
LQGTASSNASAPDAM

LMF1

421

Q96S06