Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

FUT3 FUT5 FUT6

4.18e-0661203GO:0017083
GeneOntologyMolecularFunctionalpha-(1->3)-fucosyltransferase activity

FUT3 FUT5 FUT6

1.16e-0581203GO:0046920
GeneOntologyMolecularFunction3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity

FUT3 FUT5

3.58e-0521202GO:0017060
GeneOntologyMolecularFunctionfucosyltransferase activity

FUT3 FUT5 FUT6

7.34e-05141203GO:0008417
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

RICTOR MAP3K12 IQGAP1 CCDC88A CCNYL1

1.07e-04781205GO:0043539
GeneOntologyMolecularFunctionN-acylsphingosine amidohydrolase activity

ASAH2 ASAH2B

7.37e-0471202GO:0017040
GeneOntologyMolecularFunctioninsulin receptor binding

SNX4 IRS4 CCDC88A

7.63e-04301203GO:0005158
GeneOntologyMolecularFunctionXMP 5'-nucleosidase activity

ACP3 NT5C2

9.79e-0481202GO:0106411
GeneOntologyBiologicalProcesspattern specification process

CDX1 CDX2 CDX4 MKS1 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 IFT122 FUT6 CFAP53 TCF7L1

1.33e-0552612113GO:0007389
GeneOntologyBiologicalProcessanterior/posterior pattern specification

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 TCF7L1

1.54e-052471219GO:0009952
GeneOntologyBiologicalProcessregionalization

CDX1 CDX2 CDX4 MKS1 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 IFT122 CFAP53 TCF7L1

2.49e-0547812112GO:0003002
GeneOntologyBiologicalProcessG protein-coupled purinergic receptor signaling pathway

ACP3 ADCY5 ADORA2B

5.40e-05131213GO:0035588
GeneOntologyBiologicalProcessG protein-coupled adenosine receptor signaling pathway

ACP3 ADCY5 ADORA2B

5.40e-05131213GO:0001973
GeneOntologyBiologicalProcessceramide metabolic process

ASAH2 CYP4F22 FUT3 FUT5 FUT6 ASAH2B

5.45e-051131216GO:0006672
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly

IQGAP2 IQGAP1

1.02e-0431212GO:1903475
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP1

1.02e-0431212GO:1903479
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in mitotic cytokinesis

IQGAP2 IQGAP1

1.02e-0431212GO:1902407
GeneOntologyBiologicalProcessfucosylation

FUT3 FUT5 FUT6

1.51e-04181213GO:0036065
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP1

2.03e-0441212GO:2000689
GeneOntologyBiologicalProcessregulation of insulin secretion involved in cellular response to glucose stimulus

TRPM4 TCF7L2 ANO1 ADCY5 CRHR2

2.09e-04921215GO:0061178
GeneOntologyBiologicalProcessembryonic skeletal system development

MKS1 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

2.41e-041481216GO:0048706
MousePhenothoracic vertebral transformation

CDX1 CDX2 CDX4 HOXB6 HOXC4 HOXC6

1.60e-06511006MP:0004618
MousePhenovertebral transformation

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXC4 HOXC6

1.35e-051101007MP:0003036
DomainHomeobox_metazoa

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

1.39e-07901238IPR020479
DomainHomeobox_Antennapedia_CS

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

2.13e-07211235IPR001827
DomainCaudal_act

CDX1 CDX2 CDX4

2.79e-0731233PF04731
DomainCaudal_activation_dom

CDX1 CDX2 CDX4

2.79e-0731233IPR006820
DomainANTENNAPEDIA

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

4.39e-07241235PS00032
DomainHomeobox_antennapedia

HOXB4 HOXB6 HOXB7 HOXC4

8.51e-07121234IPR017995
DomainHomeobox_CS

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

3.94e-061861239IPR017970
DomainGlyco_transf_10

FUT3 FUT5 FUT6

1.52e-0581233PF00852
DomainGlyco_tran_10_N

FUT3 FUT5 FUT6

1.52e-0581233PF17039
DomainGlyco_tran_10_N

FUT3 FUT5 FUT6

1.52e-0581233IPR031481
DomainPH-BEACH_dom

NBEAL1 WDFY4 WDFY3

1.52e-0581233IPR023362
DomainGlyco_trans_10

FUT3 FUT5 FUT6

1.52e-0581233IPR001503
Domain-

NBEAL1 WDFY4 WDFY3

1.52e-05812332.30.29.40
DomainPH_BEACH

NBEAL1 WDFY4 WDFY3

1.52e-0581233PS51783
DomainBEACH

NBEAL1 WDFY4 WDFY3

2.27e-0591233PS50197
DomainBeach

NBEAL1 WDFY4 WDFY3

2.27e-0591233PF02138
Domain-

NBEAL1 WDFY4 WDFY3

2.27e-05912331.10.1540.10
DomainBeach

NBEAL1 WDFY4 WDFY3

2.27e-0591233SM01026
DomainBEACH_dom

NBEAL1 WDFY4 WDFY3

2.27e-0591233IPR000409
DomainHomeobox

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

2.49e-052341239PF00046
DomainHOMEOBOX_1

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

2.66e-052361239PS00027
DomainHOX

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

2.75e-052371239SM00389
DomainHOMEOBOX_2

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

2.94e-052391239PS50071
DomainHomeobox_dom

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

2.94e-052391239IPR001356
DomainCeramidse_alk_C

ASAH2 ASAH2B

4.30e-0521232PF17048
DomainNEUT/ALK_ceramidase_C

ASAH2 ASAH2B

4.30e-0521232IPR031331
DomainCeramidase_alk

ASAH2 ASAH2B

4.30e-0521232IPR006823
Domain-

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

1.08e-0428312391.10.10.60
DomainRasGAP_C

IQGAP2 IQGAP1

1.29e-0431232IPR000593
DomainRasGAP_C

IQGAP2 IQGAP1

1.29e-0431232PF03836
DomainCTNNB1_binding

TCF7L2 TCF7L1

2.56e-0441232PF08347
DomainTCF/LEF

TCF7L2 TCF7L1

2.56e-0441232IPR024940
DomainCTNNB1-bd_N

TCF7L2 TCF7L1

2.56e-0441232IPR013558
DomainHomeodomain-like

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6 ZFHX4

3.55e-043321239IPR009057
Domainp53-like_TF_DNA-bd

FUT3 FUT5 FUT6 TP73

4.09e-04531234IPR008967
DomainDUF4704

NBEAL1 WDFY3

4.25e-0451232IPR031570
DomainDUF4704

NBEAL1 WDFY3

4.25e-0451232PF15787
DomainPH_BEACH

NBEAL1 WDFY3

6.34e-0461232PF14844
DomainARM-type_fold

COPG1 NBEAL1 RICTOR WDFY4 PPP2R5D PKP3 ASPM WDFY3

1.83e-033391238IPR016024
DomainCYCLIN

RBL1 CCNYL1 CCNA1

1.99e-03381233SM00385
Domain-

RBL1 CCNYL1 CCNA1

2.31e-034012331.10.472.10
DomainWD_REPEATS_1

NBEAL1 WDFY4 WDPCP UTP4 PRPF19 IFT122 WDFY3

2.46e-032781237PS00678
DomainWD_REPEATS_2

NBEAL1 WDFY4 WDPCP UTP4 PRPF19 IFT122 WDFY3

2.51e-032791237PS50082
DomainWD_REPEATS_REGION

NBEAL1 WDFY4 WDPCP UTP4 PRPF19 IFT122 WDFY3

2.51e-032791237PS50294
DomainCyclin-like

RBL1 CCNYL1 CCNA1

2.84e-03431233IPR013763
Domain-

COPG1 RICTOR WDFY4 PKP3 ASPM WDFY3

3.53e-0322212361.25.10.10
DomainWD40_repeat_dom

NBEAL1 WDFY4 WDPCP UTP4 PRPF19 IFT122 WDFY3

3.54e-032971237IPR017986
Domain-

NBEAL1 LMAN2L PAPPA WDFY3

3.59e-039512342.60.120.200
DomainRasGAP

IQGAP2 IQGAP1

3.72e-03141232SM00323
DomainNPIP

NPIPB8 NPIPB6

3.72e-03141232IPR009443
DomainRasGAP_CS

IQGAP2 IQGAP1

3.72e-03141232IPR023152
DomainP-loop_NTPase

DHX58 ABCA13 DNAH2 SMC5 IQGAP1 RIT1 RHOBTB1 RHOBTB2 ASPM SRL IFI44L DSEL DHX29

3.90e-0384812313IPR027417
DomainRasGAP

IQGAP2 IQGAP1

4.27e-03151232PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP2 IQGAP1

4.27e-03151232PS00509
DomainRAS_GTPASE_ACTIV_2

IQGAP2 IQGAP1

4.27e-03151232PS50018
Domain-

IQGAP2 IQGAP1

4.86e-031612321.10.506.10
DomainCarboxyPept-like_regulatory

CPN1 TENM2

5.48e-03171232IPR008969
DomainInterferon

IFNK IFNE

5.48e-03171232PF00143
DomainINTERFERON_A_B_D

IFNK IFNE

5.48e-03171232PS00252
DomainInterferon_alpha/beta/delta

IFNK IFNE

5.48e-03171232IPR000471
DomainIFabd

IFNK IFNE

5.48e-03171232SM00076
DomainRasGAP_dom

IQGAP2 IQGAP1

6.14e-03181232IPR001936
Domain-

NBEAL1 WDFY4 WDPCP UTP4 PRPF19 IFT122 WDFY3

6.56e-0333312372.130.10.10
PathwayKEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5 FUT6

3.75e-0651033M47966
PathwayKEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5 FUT6

7.46e-0661033M47967
PathwayREACTOME_RHO_GTPASE_CYCLE

CUL3 IQGAP2 LEMD3 SH3BP1 FAM91A1 NCF4 IQGAP1 CCDC88A RHOBTB1 RHOBTB2 COPS4 MTR

1.06e-0445010312M27078
PathwayREACTOME_RHOBTB_GTPASE_CYCLE

CUL3 RHOBTB1 RHOBTB2 COPS4

1.18e-04351034M41738
PathwayREACTOME_RHOBTB_GTPASE_CYCLE

CUL3 RHOBTB1 RHOBTB2 COPS4

1.47e-04371034MM15683
Pubmed

Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.

CDX1 CDX2 CDX4 HOXB4 HOXB7 HOXC4 HOXC6

1.44e-1223124728041967
Pubmed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

9.84e-1250124828188179
Pubmed

Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression.

CDX1 CDX2 CDX4 HOXB4 HOXC6

4.12e-1012124511335109
Pubmed

Cdx1 and Cdx2 are functionally equivalent in vertebral patterning.

CDX1 CDX2 CDX4 HOXB4

7.67e-105124419328777
Pubmed

Identification of 10 murine homeobox genes.

HAUS3 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

4.57e-093812461683707
Pubmed

Developmental regulation of the Hox genes during axial morphogenesis in the mouse.

CDX1 CDX2 CDX4 HOXB4

5.34e-097124415944185
Pubmed

The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

7.89e-0920124512370779
Pubmed

Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

1.03e-0821124525381007
Pubmed

Organization of human class I homeobox genes.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

1.33e-082212452576652
Pubmed

Cdx4 is a Cdx2 target gene.

CDX1 CDX2 CDX4

4.42e-083124320933081
Pubmed

Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.

CDX1 CDX2 CDX4

4.42e-083124318511567
Pubmed

Anterior expression of the caudal homologue cCdx-B activates a posterior genetic program in avian embryos.

CDX1 CDX2 CDX4

4.42e-083124311500978
Pubmed

Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes.

CDX1 CDX2 CDX4

4.42e-083124318252864
Pubmed

cdx4/lacZ and cdx2/lacZ protein gradients formed by decay during gastrulation in the mouse.

CDX1 CDX2 CDX4

4.42e-083124316281167
Pubmed

Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

FUT3 FUT5 FUT6

4.42e-08312437650030
Pubmed

Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.

FUT3 FUT5 FUT6

4.42e-083124330808544
Pubmed

[Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].

CDX1 CDX2 CDX4

4.42e-083124321518475
Pubmed

The human HOX gene family.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

5.89e-082912452574852
Pubmed

Expression of class I homeobox genes in fetal and adult murine skin.

HOXB4 HOXB6 HOXB7 HOXC4

7.45e-081212448105001
Pubmed

Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice.

CDX1 CDX2 CDX4

1.76e-074124318579683
Pubmed

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.

CDX1 CDX2 CDX4

1.76e-074124330343898
Pubmed

Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.

FUT3 FUT5 FUT6

1.76e-074124319349624
Pubmed

Selectivity, sharing and competitive interactions in the regulation of Hoxb genes.

HOXB4 HOXB6 HOXB7

1.76e-07412439501100
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

SNX4 IRS4 LEMD3 COPE PSD3 FAM91A1 RICTOR CTDNEP1 CEP350 CCDC88A PPP2R5D PMPCA PLCL2 PRPF19 HARS1 CSPP1 FTSJ3

2.08e-0710491241727880917
Pubmed

A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

CDX1 CDX2 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

2.35e-07118124716971476
Pubmed

Atlas of Hox gene expression in the developing kidney.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

2.43e-0738124515042701
Pubmed

Hox genes and the evolution of vertebrate axial morphology.

HOXB4 HOXB7 HOXC4 HOXC6

2.71e-071612447768176
Pubmed

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

2.78e-0739124533257809
Pubmed

Quantification of Hox and surfactant protein-B transcription during murine lung development.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

3.16e-0740124519204410
Pubmed

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

3.59e-0741124532479258
Pubmed

Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism.

CUL3 RHOBTB1 RHOBTB2

4.40e-075124318835386
Pubmed

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

FUT3 FUT5 FUT6

4.40e-075124329593094
Pubmed

Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.

HOXB6 HOXB7 HOXC4 HOXC6

4.53e-0718124423359544
Pubmed

Reduction of Hox gene expression by histone H1 depletion.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

4.59e-0743124522701719
Pubmed

Nomenclature for human homeobox genes.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

5.16e-074412451973146
Pubmed

Vertebrate homeobox gene nomenclature.

HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

7.23e-074712451358459
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CUL3 COPG1 LEMD3 COPE HAUS3 SMC5 IQGAP1 CEP350 PPP2R5D KAT8 CHEK2 ASPM COPS4 KLHL42 PRPF19 ZMYM1 PCM1

7.89e-0711551241720360068
Pubmed

MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein.

CUL3 RHOBTB1 RHOBTB2

8.78e-076124322709582
Pubmed

Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence.

CDX1 CDX2 CDX4 HOXB4

8.79e-0721124422675207
Pubmed

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.

HOXB4 HOXB6 HOXC4 HOXC6

8.79e-0721124430254164
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

LEMD3 PIEZO1 COPE PSD3 RICTOR NDUFS6 CCDC88A PPP2R5D PMPCA UTP4 ASPM COPS4 MTR PRPF19 IFT122 CSPP1 DHX29 PCM1 FTSJ3

1.39e-0614871241933957083
Pubmed

Sequence and embryonic expression of the murine Hox-3.5 gene.

HOXB4 HOXC4 HOXC6

1.53e-06712431363091
Pubmed

Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations.

HOXB4 HOXC4 HOXC6

1.53e-06712438660891
Pubmed

Gene organization of murine homeobox-containing gene clusters.

HOXB4 HOXB6 HOXB7

1.53e-06712432906328
Pubmed

The murine and Drosophila homeobox gene complexes have common features of organization and expression.

HOXB4 HOXB6 HOXB7

1.53e-06712432566383
Pubmed

Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene.

HOXB4 HOXB6 HOXB7

1.53e-06712432463210
Pubmed

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

HOXB4 HOXB6 HOXC4 HOXC6

1.55e-062412449367423
Pubmed

Fine mapping of human HOX gene clusters.

HOXB6 HOXB7 HOXC4 HOXC6

2.17e-062612448646877
Pubmed

Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system.

HOXB4 HOXB6 HOXB7

2.45e-06812432570724
Pubmed

New murine homeoboxes: structure, chromosomal assignment, and differential expression in adult erythropoiesis.

HOXB4 HOXB6 HOXB7

2.45e-06812432890503
Pubmed

Expression of HOX homeogenes in human neuroblastoma cell culture lines.

HOXB4 HOXB6 HOXB7

2.45e-06812431981366
Pubmed

Role of Cdx factors in early mesodermal fate decisions.

CDX1 CDX2 CDX4

2.45e-068124330936115
Pubmed

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.

HOXB4 HOXB6 HOXB7 HOXC6

3.41e-0629124423843306
Pubmed

Pdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic islets.

CDX1 CDX2 CDX4

3.66e-069124315888377
Pubmed

A yeast artificial chromosome containing the mouse homeobox cluster Hox-2.

HOXB4 HOXB6 HOXB7

3.66e-06912431972280
Pubmed

Region-specific gastrointestinal Hox code during murine embryonal gut development.

HOXB4 HOXB7 HOXC4

3.66e-069124311869294
Pubmed

The murine Hox-2 genes display dynamic dorsoventral patterns of expression during central nervous system development.

HOXB4 HOXB6 HOXB7

3.66e-06912431685115
Pubmed

Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation.

HOXB6 HOXB7 HOXC6

3.66e-069124315087118
Pubmed

Sf3b4 regulates chromatin remodeler splicing and Hox expression.

HOXB4 HOXB6 HOXC4 HOXC6

5.12e-0632124437167859
Pubmed

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.

HOXB4 HOXB6 HOXB7

5.21e-061012432571936
Pubmed

Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.

HOXB4 HOXB6 HOXC6

7.15e-0611124316024804
Pubmed

A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations.

HOXB4 HOXB6 HOXB7

7.15e-0611124310885747
Pubmed

Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung.

HOXB4 HOXB6 HOXB7

9.51e-061212439415485
Pubmed

Complete mutation analysis panel of the 39 human HOX genes.

HOXB6 HOXB7 HOXC4 HOXC6

1.03e-0538124411857506
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

PIEZO1 NOL6 CEP350 PPP2R5D ASPM PCM1 FTSJ3

1.10e-05210124716565220
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CUL3 SNX4 FAM91A1 HAUS3 NDUFS6 IQGAP1 CEP350 PPIG CCDC88A PPP2R5D LYN PCM1 FTSJ3

1.19e-058531241328718761
Pubmed

The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.

HOXB6 HOXC4 HOXC6

1.23e-051312438887324
Pubmed

Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development.

HOXB4 HOXB6 HOXB7

1.23e-0513124324525295
Pubmed

A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.

HOXB4 HOXB6 HOXC6

1.23e-051312438625838
Pubmed

The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing beta- and p120-catenin tyrosine phosphorylation.

CDX1 CDX2

1.26e-052124217463179
Pubmed

Genomic structure and promoter analysis of the mouse neutral ceramidase gene.

ASAH2 ASAH2B

1.26e-052124212435403
Pubmed

Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.

CDX1 CDX2

1.26e-052124218187048
Pubmed

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.

CDX2 TCF7L2

1.26e-052124220696899
Pubmed

The caudal-related homeodomain protein Cdx-2/3 regulates glucagon gene expression in islet cells.

CDX2 CDX4

1.26e-05212428910549
Pubmed

[Effect of human cytomegalovirus infection on the expression of hoxc4 and hoxc6 genes in the proliferation of lymphocytic progenitor cells].

HOXC4 HOXC6

1.26e-052124219236766
Pubmed

Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney.

ASAH2 ASAH2B

1.26e-052124211328816
Pubmed

Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.

ASAH2 ASAH2B

1.26e-052124219345744
Pubmed

Lactosylceramide contributes to mitochondrial dysfunction in diabetes.

ASAH2 ASAH2B

1.26e-052124226900161
Pubmed

Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.

CDX2 HOXB7

1.26e-052124226902420
Pubmed

A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.

ASAH2 ASAH2B

1.26e-052124217334805
Pubmed

Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.

ASAH2 ASAH2B

1.26e-052124226747710
Pubmed

Interactions between Cdx genes and retinoic acid modulate early cardiogenesis.

CDX1 CDX4

1.26e-052124221466798
Pubmed

Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment.

CDX2 CDX4

1.26e-052124220816799
Pubmed

Cdx1 and cdx2 expression during intestinal development.

CDX1 CDX2

1.26e-052124211040183
Pubmed

A gene family of HMG-box transcription factors with homology to TCF-1.

TCF7L2 TCF7L1

1.26e-05212421741298
Pubmed

Regulation of axial elongation by Cdx.

CDX1 CDX2

1.26e-052124234958748
Pubmed

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.

ASAH2 ASAH2B

1.26e-052124210753931
Pubmed

Differential gene expression in normal esophagus and Barrett's esophagus.

CDX1 CDX2

1.26e-052124219468668
Pubmed

The Cdx-1 and Cdx-2 homeobox genes in the intestine.

CDX1 CDX2

1.26e-052124210392709
Pubmed

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids.

ASAH2 ASAH2B

1.26e-052124216380386
Pubmed

Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination.

CUL3 RHOBTB1

1.26e-052124237575477
Pubmed

Nucleolar localisation of three Hox homeoproteins.

HOXB7 HOXC6

1.26e-05212427738096
Pubmed

Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.

FUT5 FUT6

1.26e-05212421339443
Pubmed

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

ASAH2 ASAH2B

1.26e-052124210652340
Pubmed

Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL-1 atrial myocytes.

TRPM4 PIEZO1

1.26e-052124238098265
Pubmed

Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.

ASAH2 ASAH2B

1.26e-052124214557071
Pubmed

Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.

IQGAP2 IQGAP1

1.26e-052124224998570
Pubmed

Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection.

ASAH2 ASAH2B

1.26e-052124235354041
Pubmed

IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.

IQGAP2 IQGAP1

1.26e-052124220977743
Pubmed

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu.

ASAH2 ASAH2B

1.26e-052124216126722
InteractionPLEKHG7 interactions

TCF7L2 RPS6KA4 FAM91A1 RICTOR HAUS3 MKS1 MTR IFT122

3.46e-061501218int:PLEKHG7
InteractionSULT1C4 interactions

TCF7L2 RPS6KA4 COPE FAM91A1 RICTOR HAUS3 IFT122

4.51e-061101217int:SULT1C4
InteractionCFAP184 interactions

RICTOR HAUS3 MKS1 CEP350 CCDC88A CCDC136 PCM1 TP73

6.11e-061621218int:CFAP184
InteractionALX4 interactions

CDX1 CDX2 CDX4 HOXB6 HOXC4

1.00e-05481215int:ALX4
InteractionIPO7 interactions

CUL3 CDX1 CDX2 RICTOR IQGAP1 RIT1 PPIG NPIPB6 ASPM HARS1

1.52e-0530412110int:IPO7
InteractionC6orf141 interactions

RICTOR HAUS3 MKS1 CCDC88A MTR TP73

1.94e-05921216int:C6orf141
InteractionPHIP interactions

CUL3 RICTOR SMC5 RHOBTB1 ZFHX4 RHOBTB2 COPS4 LYN

2.53e-051971218int:PHIP
InteractionPPIAL4G interactions

SMC5 MKS1 RIT1 LYN

3.00e-05301214int:PPIAL4G
GeneFamilyHOXL subclass homeoboxes

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXB7 HOXC4 HOXC6

8.08e-1152828518
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 WDFY4 WDFY3

7.41e-0698231230
GeneFamilyFucosyltransferases|Blood group antigens

FUT3 FUT5 FUT6

2.49e-0513823434
GeneFamilyWD repeat domain containing

NBEAL1 WDFY4 UTP4 PRPF19 IFT122 WDFY3

1.22e-03262826362
GeneFamilyDEAH-box helicases

DHX58 DHX29

2.34e-0316822500
GeneFamilyRho family GTPases

RHOBTB1 RHOBTB2

3.66e-0320822390
GeneFamilyBardet-Biedl syndrome associated|BBSome

WDPCP MKS1

4.03e-0321822980
CoexpressionWAGNER_APO2_SENSITIVITY

GALNT12 FUT3 FUT5 FUT6

6.37e-06261234M13240
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

SLF1 IQGAP2 HAUS3 CEP350 PPIG CCDC88A ASPM MTR ZMYM1 ZBTB11 CSPP1 DHX29 PCM1

1.33e-0565612313M18979
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PIEZO1 HMGCS2 PLCL2 MTR PAPPA TCF7L1

1.03e-061891247fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCelldroplet-Bladder-nan-3m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 HAUS3 SMC5 MKS1 PLCL2 ADAM33

1.04e-061191246018162114bc22a9780fded5887f1f78211851700
ToppCellLPS_only-Endothelial-Epi-like|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASAH2 RPS11 RHOBTB2 ASPM CYP4F22 ADAM33

1.46e-0612612464c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCellLPS_only-Endothelial-Epi-like-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASAH2 RPS11 RHOBTB2 ASPM CYP4F22 ADAM33

1.46e-061261246e065304f480a5e38532b66508b0ee87cc48bba9b
ToppCellfacs-Large_Intestine-Proximal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 CDX2 HMGCS2 HOXB4 HOXB6 HOXB7

7.69e-06168124623e0e1592d7400012d289adb10c7598285bae2e9
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

TRPM4 CDX1 RPS6KA4 PSD3 JAML CCDC88A

8.80e-061721246200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLF1 SH3BP1 ADORA2B CCDC88A RHOBTB2 CCDC136

1.07e-05178124609d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 HMGCS2 CHGB PLCL2 PAPPA TCF7L1

1.33e-051851246a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 HMGCS2 CPN1 APOBEC3B ASPM

1.46e-051881246b3cae49f0665ace0016a6441cbf9ae40755b0ea3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PSD3 TENM2 ADCY5 PLCL2 SRL PATJ

1.59e-05191124625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 HMGCS2 CPN1 PKP3 PATJ

1.59e-051911246a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

TCF7L2 IQGAP2 JAML WDFY4 CCDC88A LYN

1.64e-051921246bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

AMPD3 ACP3 JAML CCDC88A PLCL2 LYN

1.69e-05193124658e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellMacrophages-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

TCF7L2 NCF4 JAML HOXB6 HOXB7 CCDC88A

1.79e-0519512462af46e87947c16a7c2c367637e606cfbb8a78528
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 HMGCS2 HOXB6 PKP3 FUT3

1.90e-0519712469ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

IQGAP2 JAML WDFY4 CCDC88A PLCL2 LYN

1.90e-051971246f18807124b91310fcd84238484a80ecdba684679
ToppCellImmune|World / Lineage, Cell type, age group and donor

IQGAP2 JAML WDFY4 CCDC88A PLCL2 LYN

1.95e-05198124665681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellCOVID-19_Mild-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

JAML NPIPB8 PAH PAPPA IFI44L

2.64e-051251245e58c208b4355252ceabe04a468dd19a1f436182c
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L ABCA13 ACP3 JAML PLCL2

6.30e-0515012456e806a028c0519489151c181d9907e05289e27e0
ToppCellfacs-Lung-24m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPS11 NCF4 JAML WDFY4 PKP3

9.07e-0516212454e418bea07e35038b32a78a1e6632b6ec1208cdc
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 JAML WDFY4 CCDC88A LYN

9.61e-051641245b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NAT8L RPS6KA4 WDFY4 HOXB4 CCDC88A

9.89e-05165124517d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPN1 WDFY4 ADORA2B CCDC88A LYN

1.02e-04166124563dc58864268b4e7779e4c45155022556fc634f9
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMPD3 TCF7L2 TENM2 HOXB6 TCF7L1

1.05e-04167124578909f685ccd1321064eb0887caf9263e0e54879
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQGAP2 JAML WDFY4 CCDC88A ASPM

1.08e-041681245b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

NAT8L RPS6KA4 JAML WDFY4 CCDC88A

1.08e-041681245dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

AMPD3 ACP3 NOL6 IFI44L TP73

1.11e-0416912456abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L HMGCS2 WDPCP ADORA2B ZFHX4

1.11e-04169124515a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 DNAH2 CFAP54 CSPP1 CFAP53

1.11e-04169124514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCelldroplet-Thymus-nan-21m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNK NCF4 HOXB7 LYN TP73

1.17e-0417112458bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCelldroplet-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS11 NCF4 JAML WDFY4 LYN

1.20e-041721245f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPS11 NCF4 JAML WDFY4 LYN

1.20e-041721245f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 IQGAP2 HMGCS2 JAML SRL

1.20e-04172124530916a902c151907745756d14327e24adc34afef
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

AMPD3 ACP3 NOL6 KRBA2 TP73

1.23e-041731245d11705e56b6b21eec963ea224717f27680c781ed
ToppCellfacs-Lung-EPCAM-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 SH3BP1 NCF4 JAML WDFY4

1.23e-04173124550b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCell10x5'-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

NAT8L JAML WDFY4 CCDC88A ADAM33

1.30e-0417512451c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAT8L CDX2 HMGCS2 PKP3 IFNE

1.30e-0417512456759d200a133034756de9cdf2d5daceca927aac9
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX2 HMGCS2 NDUFS6 HOXB6 HOXB7

1.34e-041761245d1c4c78a6d4a4ad37912eade4b7d16ef84b9a706
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX2 HMGCS2 NDUFS6 HOXB6 HOXB7

1.34e-0417612451f46741b0d2ab64d4e9682587256c8da8893dd91
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 CDX2 HMGCS2 HOXB6 HOXB7

1.34e-0417612451dd54bfaa58541de51e5a8328651d390833bd480
ToppCellfacs-Large_Intestine-Proximal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX2 HMGCS2 NDUFS6 HOXB6 HOXB7

1.34e-0417612458c2f830124b3bd7c3a483aabe060a1d202c4a409
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA13 ADCY5 SLC8A2 ADAM33 CFAP53

1.37e-04177124530f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IQGAP2 JAML WDFY4 CCDC88A LYN

1.37e-041771245c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 DNAH2 CFAP54 CFAP53 TP73

1.37e-041771245c38138fb5ad9766c2d240811210c854338cd612e
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

ACP3 WDFY4 CCDC88A CCNYL1 CFAP53

1.41e-041781245536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX58 ANO1 CPN1 HOXB4 CCNYL1

1.41e-0417812457467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 PSD3 PLCL2 MTR PAPPA

1.45e-041791245d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 HMGCS2 CCNYL1 PATJ

1.49e-0418012458d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 ADCY5 CCNYL1 FUT3

1.49e-0418012458ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

RHOBTB1 PAH PAPPA PATJ FUT6

1.49e-041801245864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 ADCY5 HOXB7 HOXC4 PAPPA

1.49e-041801245d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 ADCY5 HOXB7 HOXC4 PAPPA

1.49e-041801245573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IQGAP2 ANO1 ADCY5 CRHR2 ZFHX4

1.52e-0418112457e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF7L2 WDPCP CCDC88A IFI44L WDFY3

1.52e-0418112452b9b460239d67fd480cee60820cdb306109d3567
ToppCellRV|World / Chamber and Cluster_Paper

TENM2 ADCY5 WDPCP PLCL2 PATJ

1.52e-041811245bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 PKP3 PLCL2 PAPPA TCF7L1

1.52e-041811245b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TCF7L2 WDPCP CCDC88A IFI44L WDFY3

1.52e-0418112452a1aa4a0ec7bc367857beaff543135e4345c835b
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 ADCY5 CCNYL1 FUT3

1.56e-041821245e98ca9df33a1a81fc83ecf73d5141a14f2bc985c
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAT8L RPS6KA4 JAML WDFY4 CCDC88A

1.56e-04182124502c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 HMGCS2 PLCL2 MTR PAPPA

1.60e-041831245b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL6 PSD3 ADORA2B MTR

1.63e-0498124495162072f3afc95e46f29db3d79ebd930bc09726
ToppCellfacs-Lung-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3BP1 NCF4 JAML WDFY4 CCDC88A

1.65e-041841245c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

RHOBTB1 PAH PAPPA PATJ FUT6

1.69e-0418512451bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNK GALNT12 HMGCS2 JAML PKP3

1.69e-04185124565dcb0a7ee64990a34a87c167b44497107f035ee
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ADCY5 CFAP54 PATJ TCF7L1

1.73e-041861245f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ADCY5 CFAP54 PATJ TCF7L1

1.77e-041871245c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

RHOBTB1 PAH PAPPA PATJ FUT6

1.77e-041871245738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

TENM2 ADCY5 PLCL2 SRL PATJ

1.77e-04187124578cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

NAT8L TRPM4 RPS6KA4 JAML CCDC88A

1.77e-0418712454d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

ABCA13 DNAH2 CFAP54 CFAP53 TP73

1.82e-04188124561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PSD3 HMGCS2 PLCL2 MTR PAPPA

1.82e-04188124558ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 HMGCS2 PLCL2 MTR PAPPA

1.86e-041891245532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NCF4 CPN1 WDFY4 HOXB4

1.90e-04102124457ad3d48adeb41f6ab65883e61d3b1e74a94ad1a
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NCF4 CPN1 WDFY4 HOXB4

1.90e-0410212440ec549ee94da5f2d7275490e90d816c645f6d4fc
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NCF4 CPN1 WDFY4 HOXB4

1.90e-04102124430fa92383898f370dabc41dd23d6907f14ba1a06
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NCF4 CPN1 WDFY4 HOXB4

1.90e-041021244c58e09aaa11b664c7d99e91f903561fa18460f05
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NCF4 CPN1 WDFY4 HOXB4

1.90e-0410212449392288e284b71f3a208d9f283e6e3c944b7dd10
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PSD3 TENM2 PLCL2 SRL PATJ

1.91e-041901245fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 CHGB GCNT4 PLCL2 PAPPA

1.91e-041901245078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 MTR PAPPA PATJ TCF7L1

1.96e-0419112453e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

IQGAP2 NCF4 JAML WDFY4 LYN

1.96e-041911245e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

NAT8L RPS6KA4 WDFY4 CCDC88A IFI44L

1.96e-04191124593adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

1.96e-0419112452b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

1.96e-04191124502e1ae144da7274171e055356d10e8d175c5347f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 GCNT4 HOXB7 PKP3 PAPPA

1.96e-0419112450a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

1.96e-04191124505867b96199a46a415848409130697c810d18937
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDX1 NBEAL1 ANO1 ADCY5 SRL

1.96e-04191124504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

1.96e-0419112454c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

1.96e-041911245de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

TCF7L2 IQGAP2 WDFY4 CCDC88A LYN

1.96e-041911245dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

IQGAP2 NCF4 WDFY4 ASPM LYN

2.01e-041921245a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TENM2 WDPCP PLCL2 SRL PATJ

2.01e-041921245ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

2.01e-04192124534505a13b8a47c9286c560122fa7861b9c331a08
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 CHGB PLCL2 PAPPA TCF7L1

2.01e-041921245fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPS11 TENM2 ZFHX4 PAPPA IFI44L

2.01e-041921245d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PIEZO1 CCDC88A ASPM IFT122 CSPP1

2.01e-0419212459cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF7L2 GALNT12 JAML HOXB6 HOXB7

2.01e-04192124557c1410ebf90c230993e065eb78385daa3360960
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMPD3 ACP3 SH3BP1 JAML FTSJ3

2.01e-041921245af453a179f3fdd4ae870f1d98a485e8c9fd726ac
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMPD3 ACP3 SH3BP1 JAML FTSJ3

2.01e-041921245176b9c1dd2c91bca46e12fa5060bfe590dc18246
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 CHGB GCNT4 PKP3 PAPPA

2.01e-041921245d5ec4cdb15620a5abfc83577353501186c2bc86a
DrugAC1MPID6

FUT3 FUT5 FUT6

3.04e-0661233CID003411618
Drugapropovir

IFNK ADORA2B PPIG CCDC88A IFNE

6.68e-06491235CID000064987
Drugcephadroxil

CDX1 CDX2 CDX4 HOXB4 HOXB6 HOXC6

7.26e-06861236CID000002610
Druggenistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TCF7L2 RBL1 PSD3 ADORA2B PPP2R5D KAT8 WDFY3 PATJ

1.20e-0519712381015_DN
Diseasealpha-(1;3)-fucosyltransferase 5 measurement

FUT3 FUT5 FUT6

2.49e-0741183EFO_0021979
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

FUT3 FUT5 FUT6

2.16e-0671183EFO_0021853
Diseasealpha-(1,3)-fucosyltransferase 5 measurement

FUT3 FUT5 FUT6

2.16e-0671183EFO_0020136
Diseasedevelopmental and epileptic encephalopathy 64 (implicated_via_orthology)

RHOBTB1 RHOBTB2

1.59e-0521182DOID:0070375 (implicated_via_orthology)
DiseaseMeckel-Gruber syndrome

WDPCP MKS1 CSPP1

2.74e-05151183C0265215
DiseaseNeurodevelopmental Disorders

CUL3 TCF7L2 ADCY5 PPP2R5D WDFY3

3.69e-05931185C1535926
Diseasebody fat percentage, fasting blood glucose measurement

TCF7L2 ADCY5

4.74e-0531182EFO_0004465, EFO_0007800
DiseaseMeckel syndrome type 1

WDPCP MKS1 CSPP1

4.87e-05181183C3714506
Diseaseserum carcinoembryonic antigen measurement

FUT3 FUT5 FUT6

6.76e-05201183EFO_0005760
Diseasecancer antigen 19.9 measurement

FUT3 FUT6

9.46e-0541182EFO_0010584
Diseasesystolic blood pressure, waist-hip ratio

HOXC4 HOXC6

9.46e-0541182EFO_0004343, EFO_0006335
Diseasepolyp of gallbladder

FUT3 FUT6

9.46e-0541182MONDO_0021416
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 WDFY3

9.46e-0541182DOID:2935 (implicated_via_orthology)
Diseasedesmoglein-2 measurement

FUT3 FUT6

1.57e-0451182EFO_0020322
Diseaselevel of V-set and immunoglobulin domain-containing protein 2 in blood serum

FUT3 FUT6

1.57e-0451182OBA_2044774
Diseaselactoperoxidase measurement

FUT3 FUT6

2.35e-0461182EFO_0020525
Diseaselithostathine-1-alpha measurement

FUT3 FUT6

3.29e-0471182EFO_0801083
Diseasemean reticulocyte volume

IQGAP2 RBL1 PIEZO1 DNAH2 CPN1 CEP350 PLCL2 CHEK2 SRL LYN PCM1

3.70e-0479911811EFO_0010701
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

RPS11 CPN1 GCNT4 ZNF517 CHEK2 FUT6

4.10e-042391186EFO_0010934
Diseasebreast ductal carcinoma (is_marker_for)

RICTOR TP73

4.37e-0481182DOID:3007 (is_marker_for)
Diseasechronic obstructive pulmonary disease

AMPD3 TCF7L2 PIEZO1 GALNT12 ADCY5 HOXC4 HOXC6 ADAM33 TCF7L1 PCM1

4.53e-0468811810EFO_0000341
Diseaseneutral ceramidase measurement

ASAH2 WDFY4

5.60e-0491182EFO_0008247
Diseasecandidiasis (implicated_via_orthology)

FUT3 FUT5 FUT6

7.33e-04441183DOID:1508 (implicated_via_orthology)
Disease1-methylxanthine measurement

AMPD3 PSD3

8.52e-04111182EFO_0021174
Diseaseobsolete_red blood cell distribution width

CUL3 RBL1 ASAH2 PIEZO1 HCN3 APOBEC3B IQGAP1 PMPCA PLCL2 CHEK2 COPS4 NT5C2 FUT3 LYN

9.90e-04134711814EFO_0005192
Diseaseaspartate aminotransferase measurement

IQGAP2 PIEZO1 RPS11 DNAH2 BECN2 CPN1 GCNT4 RHOBTB2 CHEK2 FUT6 TCF7L1

1.02e-0390411811EFO_0004736
Diseasebirth weight, parental genotype effect measurement

TCF7L2 RPS6KA4 ADCY5 IQGAP1 ZFHX4

1.07e-031921185EFO_0004344, EFO_0005939
Diseaseprostate cancer (is_implicated_in)

TCF7L2 ACP3 CHEK2 CCNA1

1.27e-031171184DOID:10283 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

TCF7L2 GALNT12 CHEK2 TP73

1.44e-031211184DOID:9256 (is_implicated_in)
Diseasesmoking behavior, body mass index

TCF7L2 KAT8 NT5C2 PATJ

1.53e-031231184EFO_0004318, EFO_0004340
DiseaseHbA1c measurement

AMPD3 CDX2 TCF7L2 RBL1 PIEZO1 ADCY5 PMPCA NPIPB6 SRL

1.59e-036751189EFO_0004541
Diseasecancer biomarker measurement

FUT3 FUT6

1.61e-03151182EFO_0005127
DiseaseCalcium channel blocker use measurement

PSD3 HOXC4 HOXC6 USP38 NT5C2

1.69e-032131185EFO_0009930
Diseaseneutrophil collagenase measurement

ABCA13 CPN1

1.83e-03161182EFO_0008248
Diseasegalectin-3 measurement

FUT3 FUT6

1.83e-03161182EFO_0008137
Diseasebody mass index, type 2 diabetes mellitus

TCF7L2 ADCY5

1.83e-03161182EFO_0004340, MONDO_0005148
Diseasebody fat percentage, type 2 diabetes mellitus

TCF7L2 ADCY5

2.07e-03171182EFO_0007800, MONDO_0005148
DiseaseBardet-Biedl syndrome 1 (disorder)

WDPCP MKS1

2.07e-03171182C2936862
DiseaseBardet-Biedl syndrome

WDPCP MKS1

2.33e-03181182cv:C0752166
Diseaseage at initiation of smoking

CUL3 WDPCP NDUFS6

2.37e-03661183EFO_0021784
Diseaseleukemia (implicated_via_orthology)

HOXB4 HOXC4

2.59e-03191182DOID:1240 (implicated_via_orthology)
Diseasebrain volume measurement

AMPD3 TCF7L2 LEMD3 GALNT12 NPIPB8 ZFHX4 NT5C2 PAPPA

2.75e-035951188EFO_0006930
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

TCF7L2 DNAH2

2.87e-03201182EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
DiseaseSchizophrenia

TCF7L2 ABCA13 PSD3 CHGB LMAN2L KAT8 PLCL2 PAH MTR PCM1

2.92e-0388311810C0036341
DiseaseJoubert syndrome 1

MKS1 CSPP1

3.17e-03211182C4551568
Diseaselung cancer (is_implicated_in)

IRS4 RICTOR TP73

3.29e-03741183DOID:1324 (is_implicated_in)
DiseaseN-glycan measurement

FUT3 FUT6

3.48e-03221182EFO_0004999
Diseasee-selectin measurement

FUT3 FUT6

3.48e-03221182EFO_0004575
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

AMPD3 TCF7L2 ADCY5 HOXC4 HOXC6 PATJ

3.50e-033641186EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasebody fat percentage

AMPD3 TCF7L2 ADCY5 NPIPB8 HOXC4 HOXC6 PATJ

3.54e-034881187EFO_0007800
DiseaseCarcinoma of lung

RICTOR RIT1

3.80e-03231182C0684249
DiseaseBMI-adjusted fasting blood glucose measurement

TCF7L2 ADCY5

3.80e-03231182EFO_0008036
DiseaseMalignant tumor of colon

CDX2 TCF7L2 HMGCS2 CHEK2

3.87e-031591184C0007102

Protein segments in the cluster

PeptideGeneStartEntry
KYRVVYTDHQRLELE

CDX1

156

P47902
LEKEFHYSRYITIRR

CDX2

201

Q99626
HYSRYITIRRKAELA

CDX2

206

Q99626
YRVVYTDHQRLELEK

CDX4

176

O14627
ASLYYIIRELHFVRQ

CFAP54

2071

Q96N23
LFLRFYKRDKDEHYR

C6orf136

241

Q5SQH8
THVRLRIFAARIYDY

APOBEC3B

301

Q9UH17
KYRREAYHRVFVNRS

NT5C2

26

P49902
AYRNRDFRYTFHKII

ADORA2B

291

P29275
YRIRYFGHNRKQDIL

ASAH2B

131

P0C7U1
YFIRLLEIQADYHRR

SH3BP1

226

Q9Y3L3
DILVLYNLSKHYRRF

ABCA13

4716

Q86UQ4
IRRQINHIFYRFIYE

PPP2R5D

276

Q14738
RRTRKYLELYIVADH

ADAM33

206

Q9BZ11
ERDVFLYRAYLAQRK

COPE

51

O14579
DTHGRKERYYVLYIR

ARPIN

51

Q7Z6K5
HFLARERRNDELYYQ

ADCY5

1051

O95622
YRTYSKKHFRIFREV

CHEK2

136

O96017
RRFYSERYKVIALHS

DHX29

891

Q7Z478
TLAIYYHIKNRDANR

CCNYL1

146

Q8N7R7
LYRKAAVVLQNHYRA

ASPM

2881

Q8IZT6
IREKYARLAYHRFPR

AMPD3

161

Q01432
ARKRYRDRLQYFRDH

IQGAP1

821

P46940
YERSKQHIRLREVGY

NBEAL1

1171

Q6ZS30
VTVKYLRLDRYHHRF

LEMD3

861

Q9Y2U8
DKYLRQRNKYRFHII

OTUD1

301

Q5VV17
AYRLARHAYDKLRGL

IFT122

1011

Q9HBG6
REEFYVHYVGFNRRL

KAT8

86

Q9H7Z6
YRIRYFGHNRKQDIL

ASAH2

746

Q9NR71
ITRNLKLRFYGHRQY

IFI44L

136

Q53G44
RRYYEELLKYSRDHL

FAM91A1

61

Q658Y4
RYKERLHDIEFYKAR

CCDC88A

331

Q3V6T2
YLERVDEQHRRKYAR

HMGCS2

491

P54868
VRKRLNELRELVHYY

PCM1

496

Q15154
HKLKEELRQDYRRYL

CSPP1

121

Q1MSJ5
YARVLDYRRKFIEAA

COPS4

191

Q9BT78
HTGQVYDDKDYRRIR

NDUFS6

41

O75380
EYLRKVINSLAVYRH

NPIPB8

36

E9PQR5
NQRYFRKRALYLAHL

NOL6

196

Q9H6R4
ILDDKQRKYDLHYRI

CRHR2

101

Q13324
QRKYDLHYRIALVVN

CRHR2

106

Q13324
YRRYRQFHALQSKLE

NCF4

56

Q15080
NLHYDTFLVIRYVKR

LMAN2L

206

Q9H0V9
HLYQRQYFKEAEVRV

RPS6KA4

126

O75676
RDGRRKVDYILVYHH

ANO1

56

Q5XXA6
KVVRYRVVNLYEDDH

PAPPA

351

Q13219
RQRIHEYYEHRYQGK

HCN3

381

Q9P1Z3
KDEQLHRFVRRLLYF

RICTOR

566

Q6R327
ARRKQFADIAYNYRH

PAH

156

P00439
RSKEYHRYREQEYRR

PPIG

586

Q13427
ELEKEFHYNRYLTRR

HOXB4

176

P17483
LEKEFHYNRYLTRRR

HOXB6

161

P17509
ELEKEFHYNRYLTRR

HOXB7

151

P09629
LEKEFHFNRYLTRRR

HOXC6

156

P09630
SNHVYERRLIEKYIA

PRPF19

21

Q9UMS4
EQHYELGEYIRKRYR

ACP3

76

P15309
KRRHGDEDTYYLQVR

TP73

346

O15350
HYRDYSALKRQQLEL

BECN2

211

A8MW95
IREQKIYHKYLAQRR

CFAP53

336

Q96M91
IYHKYLAQRREEEKA

CFAP53

341

Q96M91
SKYARRFFHHLLRYQ

WDPCP

571

O95876
HRYDDLVRTLYKVQN

CPN1

26

P15169
VRNRYTHVKDEVRYE

GCNT4

56

Q9P109
DVFERYYKQHLARRL

CUL3

426

Q13618
YQYLREAEIRHRPKA

CCNA1

216

P78396
ELRRYFHRIDNFLKE

IFNK

161

Q9P0W0
LEKEFHYNRYLTRRR

HOXC4

171

P09017
SKRRHYDTDEVRQYI

CEP350

586

Q5VT06
EQRVYALHLRRYNDA

DHX58

276

Q96C10
FKELYYHRNPRARLE

GALNT12

391

Q8IXK2
YEIELRKHRDIYRQL

HAUS3

391

Q68CZ6
LARYLQELDKDHARY

FUT6

301

P51993
REHYERKLERANNLY

MAP3K12

426

Q12852
AYIERKNYIHRDLRA

LYN

356

P07948
KYIRFIYNRVVLEHE

COPG1

471

Q9Y678
HYRKQEFRDDIKRLY

DNAH2

2791

Q9P225
YDRVAQLDQLLHYRK

CHGB

601

P05060
DAEYIRALRRHLVYY

DSEL

981

Q8IZU8
NIKRYHIAKVYRRDN

HARS1

146

P12081
EYLRKVINSLAVYRH

NPIPB6

36

E9PJ23
VRRQYRLHHYLDFIY

CYP4F22

241

Q6NT55
RLQVKMYFRRIHDYL

IFNE

141

Q86WN2
RDRIRYYVHKEELFD

KRBA2

181

Q6ZNG9
PARLEYYENARKFRH

IRS4

106

O14654
IVIRRDYLHYIRKYN

RPS11

86

P62280
RVRYYQSLQAHLKVD

FUT3

206

P21217
ARYLQELDKDHARYL

FUT5

316

Q11128
AKINREVLHSYLRNY

PMPCA

231

Q10713
YRLNYEHDNISLKRV

UTP4

416

Q969X6
RARVADRLYGVYKVH

SNX4

241

O95219
FYRKVYHLASVRLRD

RBL1

791

P28749
ARKSYLSRLQYFRDH

IQGAP2

736

Q13576
RAKEEIVFRYYHKLR

JAML

176

Q86YT9
KVRSNSRIYHRYFLL

PLCL2

151

Q9UPR0
IRQDHYESLKERRYL

MTR

916

Q99707
YLKEEDHYQRARKER

RHOBTB2

671

Q9BYZ6
RRDKFYHLAKETGYR

FTSJ3

11

Q8IY81
YDRNIRTEKIYDDHR

TENM2

1851

Q9NT68
YLKEEDHYQRVKRER

RHOBTB1

656

O94844
LQELRERYHFLNEEY

CCDC136

226

Q96JN2
DNSRSILKRRYYRQH

CTDNEP1

146

O95476
QYNKLHRDFRAKGYR

PKP3

776

Q9Y446
EVRAFRYQERFKHIL

SPRYD3

36

Q8NCJ5
SFRVYDLRHKREKDY

ZFHX4

226

Q86UP3
TLYYQRRQRHRKTFA

ZBTB11

46

O95625
YEDIKEVHKRRYLLQ

WDFY3

2611

Q8IZQ1
RRVFKDLYGRHKEYL

MKS1

281

Q9NXB0
RSFHEVREFKQLIYR

RIT1

106

Q92963
YELARKERQLHSQLY

TCF7L1

396

Q9HCS4
KVRLVVYRDEAHYRD

PATJ

1511

Q8NI35
DDYSAVLQRLRKIYH

SRL

51

Q86TD4
RIHALLVDRYLQTYK

SRL

341

Q86TD4
QAKYYELARKERQLH

TCF7L2

396

Q9NQB0
RRRGQELYASLYKDH

WDFY4

2231

Q6ZS81
LRFSYDQKYHVRRKI

USP38

766

Q8NB14
TLRKHIYRAQAVRYN

SLF1

376

Q9BQI6
KAFRRSYTLNEHYRL

ZNF517

431

Q6ZMY9
LIRYQRKHDYVGERA

ZIM2

451

Q9NZV7
KRFIYRQDLYKHQID

ZNF225

351

Q9UK10
FEAIVYRRQEHYRRQ

PIEZO1

941

Q92508
ELRFYRHYAKLNFVI

ZMYM1

1026

Q5SVZ6
YKQDVERFYERKRHL

SMC5

246

Q8IY18
ERERVLIHFSNRYFY

PSD3

651

Q9NYI0
LYWKAQRYRLIREFH

TRPM4

1056

Q8TD43
KAFYKRYRLTEHERA

ZNF649

241

Q9BS31
RKLIEQSDYFRALYR

KLHL42

21

Q9P2K6
YALLHQQKSRAFYRI

SLC8A2

341

Q9UPR5
SLAERLFFQVRYHRY

NAT8L

281

Q8N9F0