Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GP6 TNFRSF25 DRD1 MRGPRD SIGLEC8 OR2G6 DDR2 OR4Q3 TNFRSF18 LTB4R2 SSTR1 GRM4 PTGER1 PTGFR OR6N1 OR51F1 ADRA1D OXTR EGFR PKD1 OR1A1 MRGPRX4 OR52K2 KIT OR7A2P

4.43e-05135315525GO:0004888
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC4A8 TMC7 ASIC1 ABCA13 SLCO2B1 AQP11 TRPC3 MFSD9 SLC9B1P1 ANO5 AQP1 SLC26A1 SLC22A12 ITPR2 SLC9B1 SLC9A1 CLCA1 SLC17A1 SLC22A10 PKD1 SLC4A10 ABCC10

1.18e-04118015522GO:0022857
GeneOntologyMolecularFunctionadenosylhomocysteinase activity

AHCYL1 AHCYL2

1.79e-0431552GO:0004013
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-sulfur bonds

AHCYL1 AHCYL2

1.79e-0431552GO:0046508
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

1.79e-0431552GO:0140892
GeneOntologyMolecularFunctionicosanoid receptor activity

LTB4R2 PTGER1 PTGFR

2.39e-04161553GO:0004953
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC4A8 SLC9B1 SLC9A1 SLC4A10

3.41e-04431554GO:0140828
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A8 ANO5 SLC26A1 CLCA1 SLC17A1 SLC4A10 ABCC10

3.84e-041711557GO:0015103
GeneOntologyMolecularFunctiontransporter activity

SLC4A8 TMC7 ASIC1 ABCA13 SLCO2B1 AQP11 TRPC3 MFSD9 SLC9B1P1 ANO5 AQP1 SLC26A1 SLC22A12 ITPR2 SLC9B1 SLC9A1 CLCA1 SLC17A1 SLC22A10 PKD1 SLC4A10 ABCC10

4.06e-04128915522GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC4A8 SLCO2B1 SLC9B1P1 SLC26A1 SLC9B1 SLC9A1 SLC17A1 SLC22A10 SLC4A10

5.21e-042961559GO:0015291
GeneOntologyMolecularFunctionG protein-coupled receptor activity

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 GRM4 PTGER1 PTGFR OR6N1 OR51F1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2 OR7A2P

5.22e-0488415517GO:0004930
GeneOntologyMolecularFunctionantiporter activity

SLC4A8 SLC9B1P1 SLC26A1 SLC9B1 SLC9A1 SLC4A10

7.35e-041381556GO:0015297
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC4A8 ASIC1 AQP11 TRPC3 ANO5 AQP1 SLC26A1 ITPR2 SLC9B1 SLC9A1 CLCA1 SLC17A1 PKD1 SLC4A10 ABCC10

8.42e-0475815515GO:0015318
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A8 SLC4A10

8.80e-0461552GO:0008510
GeneOntologyMolecularFunctioncollagen receptor activity

GP6 DDR2

8.80e-0461552GO:0038064
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC4A8 ABCA13 SLCO2B1 SLC9B1P1 SLC26A1 SLC9B1 SLC9A1 SLC17A1 SLC22A10 SLC4A10 ABCC10

1.27e-0347715511GO:0022804
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC4A8 AQP11 VPS33A SLC9B1P1 SLC9B1 SLC9A1 SLC4A10

6.71e-06941547GO:0051453
GeneOntologyBiologicalProcessregulation of cellular pH

SLC4A8 AQP11 VPS33A SLC9B1P1 SLC9B1 SLC9A1 SLC4A10

1.08e-051011547GO:0030641
GeneOntologyBiologicalProcessregulation of pH

SLC4A8 AQP11 VPS33A SLC9B1P1 SLC9B1 SLC9A1 SLC4A10

3.32e-051201547GO:0006885
GeneOntologyBiologicalProcessmonoatomic anion transport

AHCYL1 SLC4A8 ANO5 SLC26A1 CLCA1 SLC17A1 SLC4A10 ABCC10

7.14e-051831548GO:0006820
GeneOntologyBiologicalProcessresponse to nitrogen compound

SEL1L AHCYL1 DRD1 ASIC1 AQP11 TRPC3 DDR2 BCAR1 SST PTGER1 AQP1 ADCY5 SLC22A12 EPG5 ITPR2 TYR SLC9A1 OXTR EGFR MTHFR MRGPRX4 SMPD1 CTNNB1

7.15e-05127215423GO:1901698
GeneOntologyCellularComponentbasolateral plasma membrane

SLC4A8 DSP SLCO2B1 AQP1 SLC26A1 SLC9A1 EGFR SLC22A10 PKD1 SLC4A10 CTNNB1 ABCC10

5.66e-0632015712GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

SLC4A8 DSP SLCO2B1 AQP1 SLC26A1 SLC9A1 EGFR SLC22A10 PKD1 SLC4A10 CTNNB1 ABCC10

1.56e-0535415712GO:0009925
GeneOntologyCellularComponentapical plasma membrane

AHCYL1 SLC4A8 SLCO2B1 DDR2 CEACAM4 MYRIP AQP1 SLC22A12 SLC9A1 OXTR EGFR SLC17A1 SLC4A10 CTNNB1

1.93e-0548715714GO:0016324
GeneOntologyCellularComponentbasal part of cell

SLC4A8 DSP SLCO2B1 AQP1 SLC26A1 SLC9A1 EGFR SLC22A10 PKD1 SLC4A10 CTNNB1 ABCC10

2.97e-0537815712GO:0045178
GeneOntologyCellularComponentapical part of cell

AHCYL1 SLC4A8 SLCO2B1 DDR2 CEACAM4 MYRIP AQP1 SLC22A12 SLC9A1 OXTR EGFR SLC17A1 INSC SLC4A10 CTNNB1

4.16e-0559215715GO:0045177
GeneOntologyCellularComponentdense core granule

STXBP5 MYRIP SST AQP1

8.30e-04561574GO:0031045
DomainAdoHcyase_NAD

AHCYL1 AHCYL2

1.94e-0431512SM00997
DomainAdoHcyase

AHCYL1 AHCYL2

1.94e-0431512SM00996
DomainAdoHcyase_NAD

AHCYL1 AHCYL2

1.94e-0431512PF00670
DomainADOHCYASE_1

AHCYL1 AHCYL2

1.94e-0431512PS00738
DomainADOHCYASE_2

AHCYL1 AHCYL2

1.94e-0431512PS00739
DomainAdoHcyase

AHCYL1 AHCYL2

1.94e-0431512PF05221
DomainAdo_hCys_hydrolase_NAD-bd

AHCYL1 AHCYL2

1.94e-0431512IPR015878
DomainS-Ado-L-homoCys_hydrolase_CS

AHCYL1 AHCYL2

1.94e-0431512IPR020082
DomainAdenosylhomocysteinase

AHCYL1 AHCYL2

1.94e-0431512IPR000043
DomainDUF2476

PRR23A PRR23B

3.85e-0441512PF10630
DomainFAM86

FAM86B1 FAM86B2

3.85e-0441512IPR029426
DomainPRR23

PRR23A PRR23B

3.85e-0441512IPR018903
DomainFAM86

FAM86B1 FAM86B2

3.85e-0441512PF14904
DomainARM-type_fold

SMG1 NCDN ITPR2 SCYL2 ELMO3 AOPEP INSC ARMC5 PUM3 CTNNB1

4.44e-0433915110IPR016024
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

6.39e-0451512IPR003024
DomainGPCR_Rhodpsn_7TM

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 PTGER1 PTGFR OR6N1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2

1.09e-0367015114IPR017452
DomainPROTEIN_KINASE_TYR

DDR2 AATK EGFR PEAK1 KIT

1.15e-03971515PS00109
DomainTyr_kinase_AS

DDR2 AATK EGFR PEAK1 KIT

1.15e-03971515IPR008266
Domain7tm_1

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 PTGER1 PTGFR OR6N1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2

1.21e-0367715114PF00001
DomainANION_EXCHANGER_2

SLC4A8 SLC4A10

1.33e-0371512PS00220
DomainANION_EXCHANGER_1

SLC4A8 SLC4A10

1.33e-0371512PS00219
DomainG_PROTEIN_RECEP_F1_1

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 PTGER1 PTGFR OR6N1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2

1.35e-0368515114PS00237
DomainG_PROTEIN_RECEP_F1_2

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 PTGER1 PTGFR OR6N1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2

1.46e-0369115114PS50262
DomainGPCR_Rhodpsn

DRD1 MRGPRD OR2G6 OR4Q3 LTB4R2 SSTR1 PTGER1 PTGFR OR6N1 ADRA1D OXTR OR1A1 MRGPRX4 OR52K2

1.48e-0369215114IPR000276
DomainSec1-like

SCFD2 VPS33A

1.76e-0381512IPR001619
DomainSec-1-like_dom2

SCFD2 VPS33A

1.76e-0381512IPR027482
DomainSec1

SCFD2 VPS33A

1.76e-0381512PF00995
DomainProstanoid_rcpt

PTGER1 PTGFR

1.76e-0381512IPR008365
Domain-

SCFD2 VPS33A

1.76e-03815123.40.50.1910
DomainAlkaline_phosphatase_core

SULF2 STS PIGO

1.97e-03311513IPR017850
DomainAlkaline_Pase-like_a/b/a

SULF2 STS PIGO

1.97e-03311513IPR017849
Domain-

SULF2 STS PIGO

1.97e-033115133.40.720.10
DomainBPI1

BPIFC BPIFB1

2.25e-0391512SM00328
Domain-

SLC4A8 SLC4A10

2.25e-03915123.40.1100.10
DomainBand3_cytoplasmic_dom

SLC4A8 SLC4A10

2.25e-0391512IPR013769
DomainBand_3_cyto

SLC4A8 SLC4A10

2.25e-0391512PF07565
DomainLBP_BPI_CETP_C

BPIFC BPIFB1

2.80e-03101512PF02886
DomainPTrfase/Anion_transptr

SLC4A8 SLC4A10

2.80e-03101512IPR016152
DomainHCO3_transpt_euk

SLC4A8 SLC4A10

2.80e-03101512IPR003020
DomainHCO3_cotransp

SLC4A8 SLC4A10

2.80e-03101512PF00955
DomainHCO3_transpt_C

SLC4A8 SLC4A10

2.80e-03101512IPR011531
DomainMethyltransf_16

FAM86B1 FAM86B2

3.40e-03111512IPR019410
DomainMethyltransf_16

FAM86B1 FAM86B2

3.40e-03111512PF10294
DomainMRGPCRFAMILY

MRGPRD MRGPRX4

3.40e-03111512IPR026234
DomainMFS_1

MFSD9 SLC22A12 SLC17A1 SLC22A10

3.52e-03771514PF07690
DomainMFS

MFSD9 SLC22A12 SLC17A1 SLC22A10

3.52e-03771514IPR011701
DomainPkinase_Tyr

DDR2 AATK EGFR MAP3K21 KIT

3.99e-031291515PF07714
DomainLipid-bd_serum_glycop_C

BPIFC BPIFB1

4.06e-03121512IPR001124
DomainARM

INSC ARMC5 CTNNB1

4.11e-03401513SM00185
DomainMFS_dom

SLCO2B1 MFSD9 SLC22A12 SLC17A1 SLC22A10

4.68e-031341515IPR020846
DomainLBP_BPI_CETP

BPIFC BPIFB1

4.78e-03131512PF01273
DomainBPI/LBP/Plunc

BPIFC BPIFB1

4.78e-03131512IPR032942
DomainBactericidal_perm-incr_a/b_dom

BPIFC BPIFB1

4.78e-03131512IPR017943
DomainLipid-bd_serum_glycop_N

BPIFC BPIFB1

4.78e-03131512IPR017942
DomainSer-Thr/Tyr_kinase_cat_dom

DDR2 AATK EGFR MAP3K21 KIT

5.30e-031381515IPR001245
DomainMIP

AQP11 AQP1

5.54e-03141512PF00230
DomainEamA

SLC35G4 SLC35G5

5.54e-03141512PF00892
DomainNa_H_Exchanger

SLC9B1 SLC9A1

5.54e-03141512PF00999
DomainMIP

AQP11 AQP1

5.54e-03141512PS00221
DomainEamA_dom

SLC35G4 SLC35G5

5.54e-03141512IPR000620
DomainCation/H_exchanger

SLC9B1 SLC9A1

5.54e-03141512IPR006153
DomainTyr_kinase_cat_dom

DDR2 EGFR MAP3K21 KIT

5.66e-03881514IPR020635
DomainTyrKc

DDR2 EGFR MAP3K21 KIT

5.66e-03881514SM00219
Domain-

AQP11 AQP1

6.36e-031515121.20.1080.10
DomainAquaporin-like

AQP11 AQP1

6.36e-03151512IPR023271
DomainMIP

AQP11 AQP1

6.36e-03151512IPR000425
DomainARM-like

SMG1 SCYL2 ELMO3 INSC ARMC5 PUM3 CTNNB1

6.46e-032701517IPR011989
DomainArmadillo

INSC ARMC5 CTNNB1

6.48e-03471513IPR000225
DomainLDLRA_1

LDLRAD1 PKD1 LRP3

6.87e-03481513PS01209
DomainSulfatase_CS

SULF2 STS

7.23e-03161512IPR024607
DomainLDLRA_2

LDLRAD1 PKD1 LRP3

7.27e-03491513PS50068
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SEL1L SLC4A8 ASIC1 SLCO2B1 AQP11 TRPC3 SLC9B1P1 ANO5 AHCYL2 AQP1 SLC26A1 SLC22A12 SLC9B1 SLC9A1 LIPC CLCA1 SLC17A1 SLC4A10 ABCC10

1.58e-0668111219MM14985
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

LTB4R2 PTGER1 PTGFR ITPR2 ADRA1D OXTR

2.63e-06501126M47951
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SEL1L SLC4A8 ASIC1 SLCO2B1 AQP11 TRPC3 ANO5 AHCYL2 AQP1 SLC26A1 ADCY5 SLC22A12 SLC9B1 SLC9A1 LIPC CLCA1 SLC17A1 SLC4A10 ABCC10

4.93e-0673611219M27287
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 AHCYL2 SLC4A10

5.63e-05101123M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 AHCYL2 SLC4A10

5.63e-05101123MM15073
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

DRD1 LTB4R2 PTGER1 PTGFR ITPR2 ADRA1D OXTR EGFR

8.59e-051781128M2890
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ASIC1 TRPC3 SLC9B1P1 ANO5 SLC9B1 CLCA1

1.35e-04991126MM14910
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

LTB4R2 PTGER1 PTGFR

1.67e-04141123MM15012
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

LTB4R2 PTGER1 PTGFR

2.07e-04151123M10620
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A8 AHCYL2 SLC26A1 SLC9A1 SLC17A1 SLC4A10

2.18e-041081126M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A8 AHCYL2 SLC26A1 SLC9A1 SLC17A1 SLC4A10

2.29e-041091126MM15074
PathwayWP_GPCRS_NONODORANT

DRD1 MRGPRD LTB4R2 SSTR1 GRM4 PTGER1 PTGFR ADRA1D OXTR

2.68e-042661129MM15843
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

TRPC3 LTB4R2 PTGER1 PTGFR ITPR2 ADRA1D OXTR EGFR

2.68e-042101128MM15043
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

TRPC3 LTB4R2 PTGER1 PTGFR ITPR2 ADRA1D OXTR EGFR

3.34e-042171128M18437
PathwayREACTOME_SIGNALING_BY_GPCR

AHCYL1 DRD1 TRPC3 LTB4R2 SST SSTR1 GRM4 PTGER1 PTGFR ADCY5 ITPR2 ADRA1D OXTR EGFR ARHGEF7

4.32e-0470211215M746
PathwayREACTOME_SIGNALING_BY_GPCR

DRD1 TRPC3 LTB4R2 SST SSTR1 GRM4 PTGER1 PTGFR ADCY5 ITPR2 ADRA1D OXTR EGFR ARHGEF7

5.91e-0464611214MM14962
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC4A8 SLCO2B1 AHCYL2 SLC26A1 SLC22A12 SLC9A1 SLC17A1 SLC4A10

6.17e-042381128MM15076
Pubmed

Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.

AQP1 PKD1 CTNNB1

8.97e-075157325573755
Pubmed

A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

AQP1 PKD1 CTNNB1

8.97e-075157319774080
Pubmed

Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.

MRGPRD CEACAM4 SST MRGPRX4

1.83e-0620157435875660
Pubmed

Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant.

EGFR PKD1 CTNNB1

3.12e-067157312095915
Pubmed

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

MRGPRD ASIC1 TRPC3 MRGPRX4

3.31e-0623157416446141
Pubmed

Distinct subdomain organization and molecular composition of a tight junction with adherens junction features.

CLDN6 CLDN9 CTNNB1

4.97e-068157317130295
Pubmed

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.

LTB4R2 PTGER1 PTGFR KIT

6.47e-0627157423624557
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 AHCYL1 SREBF2 YTHDC2 NOL9 ZZEF1 JMJD1C NCDN SULF2 GTF3C1 WASHC5 ARHGEF7 ARMC5

8.76e-066501571338777146
Pubmed

Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.

BCAR1 PKD1 CTNNB1

1.06e-0510157311113628
Pubmed

Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.

VPS33A TYR KIT

1.45e-051115738812411
Pubmed

Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts.

LTB4R2 PTGER1 PTGFR KIT

1.48e-0533157439002541
Pubmed

Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).

AQP1 SLC9A1 SLC4A10

1.93e-0512157321705333
Pubmed

Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus.

CLDN6 CLDN9

2.02e-052157217804490
Pubmed

Acid sphingomyelinase mediates 50-Hz magnetic field-induced EGF receptor clustering on lipid raft.

EGFR SMPD1

2.02e-052157226915736
Pubmed

Overexpression of EGFR and absence of C-KIT expression correlate with poor prognosis in salivary gland carcinomas.

EGFR KIT

2.02e-052157218983466
Pubmed

In vitro characterization of somatostatin receptors in the human thymus and effects of somatostatin and octreotide on cultured thymic epithelial cells.

SST SSTR1

2.02e-05215729886848
Pubmed

Immunohistochemical Expression of Epidermal Growth Factor Receptor and c-Kit in Triple Negative Breast Cancer.

EGFR KIT

2.02e-052157227504546
Pubmed

Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex.

SST ITPR2

2.02e-052157235563706
Pubmed

Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy.

EGFR CSMD1

2.02e-052157234404439
Pubmed

A novel testis-specific Na+/H+ exchanger is involved in sperm motility and fertility.

SLC9B1P1 SLC9B1

2.02e-052157220036903
Pubmed

Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model.

AQP11 PKD1

2.02e-052157224854278
Pubmed

Downregulation of CLDN6 inhibits cell proliferation, migration, and invasion via regulating EGFR/AKT/mTOR signalling pathway in hepatocellular carcinoma.

CLDN6 EGFR

2.02e-052157232056244
Pubmed

beta-Catenin and plakoglobin N- and C-tails determine ligand specificity.

DSP CTNNB1

2.02e-052157215381698
Pubmed

The WNT/MYB pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation.

CTNNB1 KIT

2.02e-052157227161149
Pubmed

Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies.

CLDN6 CLDN9

2.02e-052157223864633
Pubmed

Promotion of growth factor signaling as a critical function of β-catenin during HCC progression.

EGFR CTNNB1

2.02e-052157231015417
Pubmed

High expression and localization of β-catenin and epidermal growth factor receptor identify high risk papillary thyroid carcinoma patients.

EGFR CTNNB1

2.02e-052157230077672
Pubmed

Molecular profile of head and neck squamous cell carcinomas bearing p16 high phenotype.

EGFR CTNNB1

2.02e-052157223406730
Pubmed

Evolution of Vertebrate Solute Carrier Family 9B Genes and Proteins (SLC9B): Evidence for a Marsupial Origin for Testis Specific SLC9B1 from an Ancestral Vertebrate SLC9B2 Gene.

SLC9B1P1 SLC9B1

2.02e-052157228868326
Pubmed

Thinking and doing: the effects of dopamine and oxytocin genes and executive function on mothering behaviours.

DRD1 OXTR

2.02e-052157227620964
Pubmed

AQP1 and SLC4A10 as candidate genes for primary open-angle glaucoma.

AQP1 SLC4A10

2.02e-052157220101282
Pubmed

Epidermal growth factor receptor inhibition leads to cellular phenotype correction of DSP-mutated keratinocytes.

DSP EGFR

2.02e-052157238509711
Pubmed

β-catenin contributes to lung tumor development induced by EGFR mutations.

EGFR CTNNB1

2.02e-052157225164010
Pubmed

[A preliminary study on role of acid sphingomyelinase in receptor clustering induced by 50-Hz magnetic fields].

EGFR SMPD1

2.02e-052157220137294
Pubmed

Aberrant methylation inactivates somatostatin and somatostatin receptor type 1 in head and neck squamous cell carcinoma.

SST SSTR1

2.02e-052157225734919
Pubmed

Chemotherapeutic alteration of β-catenin and c-kit expression by imatinib in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.

CTNNB1 KIT

2.02e-052157221993766
Pubmed

Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways.

EGFR CTNNB1

2.02e-052157224047892
Pubmed

Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling.

PKD1 CTNNB1

2.02e-052157218632682
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

2.02e-052157238674160
Pubmed

Interaction Between Beta-Catenin and EGFR Expression by Immunohistochemistry Identifies Prognostic Subgroups in Early High-risk Triple-negative Breast Cancer.

EGFR CTNNB1

2.02e-052157227127145
Pubmed

KIT regulates tyrosine phosphorylation and nuclear localization of beta-catenin in mast cell leukemia.

CTNNB1 KIT

2.02e-052157217949810
Pubmed

ErbB-2 receptor cooperates with E6/E7 oncoproteins of HPV type 16 in breast tumorigenesis.

EGFR CTNNB1

2.02e-052157218156804
Pubmed

Oxytocin receptor elicits different EGFR/MAPK activation patterns depending on its localization in caveolin-1 enriched domains.

OXTR EGFR

2.02e-052157212955084
Pubmed

Genetic inactivation of β-catenin is salubrious, whereas its activation is deleterious in desmoplakin cardiomyopathy.

DSP CTNNB1

2.02e-052157237625794
Pubmed

Aquaporin 1 promotes sensitivity of anthracycline chemotherapy in breast cancer by inhibiting β-catenin degradation to enhance TopoIIα activity.

AQP1 CTNNB1

2.02e-052157232814878
Pubmed

Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women.

EGFR KIT

2.02e-052157218754326
Pubmed

Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway.

EGFR CTNNB1

2.02e-052157223928863
Pubmed

Chimeric Fc receptors identify ligand binding regions in human glycoprotein VI.

GP6 FCAR

2.02e-052157216876821
Pubmed

The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function.

AQP11 AQP1

2.02e-052157221118806
Pubmed

Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice.

TNFRSF25 CTNNB1

2.02e-052157217638904
Pubmed

Expression, localization, and signaling of prostaglandin F2 alpha receptor in human endometrial adenocarcinoma: regulation of proliferation by activation of the epidermal growth factor receptor and mitogen-activated protein kinase signaling pathways.

PTGFR EGFR

2.02e-052157214764825
Pubmed

Radiation-induced PGE2 sustains human glioma cells growth and survival through EGF signaling.

EGFR CTNNB1

2.02e-052157225749386
Pubmed

Nhe1 is a luminal Na+/H+ exchanger in mouse choroid plexus and is targeted to the basolateral membrane in Ncbe/Nbcn2-null mice.

SLC9A1 SLC4A10

2.02e-052157219369449
Pubmed

Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver.

EGFR CTNNB1

2.02e-052157216012954
Pubmed

Immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger by oral feeding or nasal instillation reduces fertility in female mice.

SLC9B1P1 SLC9B1

2.02e-052157219409551
Pubmed

Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.

PKD1 CTNNB1

2.02e-052157226739494
Pubmed

MEK inhibitor, PD98059, promotes breast cancer cell migration by inducing β-catenin nuclear accumulation.

EGFR CTNNB1

2.02e-052157229048617
Pubmed

The polycystin-1 C-type lectin domain binds carbohydrate in a calcium-dependent manner, and interacts with extracellular matrix proteins in vitro.

COL2A1 PKD1

2.02e-052157211406351
Pubmed

Sterol-regulatory-element binding protein inhibits upstream stimulatory factor-stimulated hepatic lipase gene expression.

SREBF2 LIPC

2.02e-052157215721010
Pubmed

Genetic ablation of Slc4a10 alters the expression pattern of transporters involved in solute movement in the mouse choroid plexus.

AQP1 SLC4A10

2.02e-052157222357733
Pubmed

Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice.

TNFRSF18 KIT

2.02e-052157224558202
Pubmed

The interaction of p130Cas with PKN3 promotes malignant growth.

BCAR1 PKN3

2.02e-052157230422386
Pubmed

Identification of a cross-talk between EGFR and Wnt/beta-catenin signaling pathways in HepG2 liver cancer cells.

EGFR CTNNB1

2.02e-052157233340661
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

DRD1 LINC02912 ADCY5 COL23A1 LIPC AATK CDH20 AOPEP INSC AGMO PUM3 CSMD1 PKN3 TMEM82

2.11e-058141571423251661
Pubmed

Determination of genetic predisposition to patent ductus arteriosus in preterm infants.

GP6 PTGER1 PTGFR LIPC OXTR MTHFR

2.77e-05129157619336370
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC22A12 SLC17A1 SLC22A10

4.84e-0516157319679677
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

AQP1 PKD1 CTNNB1

5.86e-0517157316472605
Pubmed

Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.

MRGPRD TRPC3 MRGPRX4

5.86e-0517157325834056
Pubmed

Motor dysfunction in type 5 adenylyl cyclase-null mice.

DRD1 ADCY5

6.06e-053157212665504
Pubmed

Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation.

EGFR CTNNB1

6.06e-053157230445978
Pubmed

Claudin-6, 7, or 9 overexpression in the human gastric adenocarcinoma cell line AGS increases its invasiveness, migration, and proliferation rate.

CLDN6 CLDN9

6.06e-053157220874001
Pubmed

Specific expression of Gsta4 in mouse cochlear melanocytes: a novel role for hearing and melanocyte differentiation.

TYR KIT

6.06e-053157218983533
Pubmed

Somatostatin actions via somatostatin receptors on the ocular surface are modulated by inflammatory processes.

SST SSTR1

6.06e-053157219106227
Pubmed

miR-141 exacerbates lung ischemia-reperfusion injury by targeting EGFR/β-catenin axis-mediated autophagy.

EGFR CTNNB1

6.06e-053157235972910
Pubmed

Clinicopathological significance of E-cadherin, β-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma.

EGFR CTNNB1

6.06e-053157222281980
Pubmed

Reduction of nuclear Y654-p-β-catenin expression through SH3GL2-meditated downregulation of EGFR in chemotolerance TNBC: Clinical and prognostic importance.

EGFR CTNNB1

6.06e-053157231960967
Pubmed

Immunohistochemical and molecular analysis of tyrosine kinase activity in desmoid tumors.

CTNNB1 KIT

6.06e-053157221195420
Pubmed

Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy.

DSP CTNNB1

6.06e-053157216823493
Pubmed

Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line, MGN3-1 in vitro.

DRD1 OXTR

6.06e-053157221521750
Pubmed

The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells.

TNFRSF25 KIT

6.06e-053157224368564
Pubmed

Leukotriene B4 Receptor 2 Is Critical for the Synthesis of Vascular Endothelial Growth Factor in Allergen-Stimulated Mast Cells.

LTB4R2 KIT

6.06e-053157227489284
Pubmed

Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

BCAR1 PEAK1

6.06e-053157220534451
Pubmed

Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins.

CLDN6 CLDN9

6.06e-053157216774906
Pubmed

Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth.

EGFR ARHGEF7

6.06e-053157216892055
Pubmed

Receptor tyrosine kinases in sinonasal undifferentiated carcinomas--evaluation for EGFR, c-KIT, and HER2/neu expression.

EGFR KIT

6.06e-053157219283847
Pubmed

AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin.

AQP1 CTNNB1

6.06e-053157219584911
Pubmed

Expression of p130cas, E-cadherin and β-catenin and their correlation with clinicopathological parameters in non-small cell lung cancer: p130cas over-expression predicts poor prognosis.

BCAR1 CTNNB1

6.06e-053157223042269
Pubmed

HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.

EGFR PKD1

6.06e-053157223152903
Pubmed

A comparison of pigment cell development in albino, steel, and dominant-spotting mutant mouse embryos.

TYR KIT

6.06e-05315724920403
Pubmed

An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.

AHCYL1 AHCYL2

6.06e-053157219220705
Pubmed

Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study.

SLC22A12 SLC17A1

6.06e-053157226290326
Pubmed

Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain.

MRGPRD SST

6.06e-053157233692491
Pubmed

No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW.

SLC22A12 MTHFR

6.06e-053157223544272
Pubmed

Sodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertility.

SLC9B1P1 SLC9B1

6.06e-053157227010853
Pubmed

Myometrial oxytocin receptor mRNA concentrations at preterm and term delivery - the influence of external oxytocin.

PTGFR OXTR

6.06e-053157219347709
Pubmed

Abnormal beta-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features.

EGFR CTNNB1

6.06e-053157215791567
Pubmed

Distribution and expression pattern of claudins 6, 7, and 9 in diffuse- and intestinal-type gastric adenocarcinomas.

CLDN6 CLDN9

6.06e-053157219960275
Pubmed

The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors.

SST SSTR1

6.06e-053157215247250
Pubmed

Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.

SULF2 EGFR

6.06e-053157225448158
Pubmed

Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling.

SSTR1 EGFR

6.06e-053157221419811
Cytoband19q13.42

MYADM NLRP2 SSC5D ISOC2 FCAR

7.39e-05125157519q13.42
GeneFamilySolute carriers

SLC4A8 SLCO2B1 SLC26A1 SLC22A12 SLC35G4 SLC9B1 SLC9A1 SLC17A1 SLC22A10 SLC4A10 SLC35G5

4.04e-0539511411752
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

FAM86B2 SLCO2B1 AQP11 TMEM135 PAQR5 AQP1 PTGFR CLDN6 SLC22A12 CLDN9 ELMO3 LIPC SLC17A1 A4GNT MAP3K21 PIGO ABCC10 TMEM82

4.63e-0678414118gudmap_developingKidney_e15.5_early proxim tubul_1000
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TNFRSF25 MYRIP TNFRSF18 PIGV CLDN9 COL23A1 CYP26C1 SLC4A10 KIT

2.62e-09146157940fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYADM TNFRSF25 MYRIP TNFRSF18 PIGV FRY CYP26C1 KIT

4.75e-071951578d70b49f6b9c6c4422adb2936c837a1af7569fb0a
ToppCellmLN-ILC-ILC|mLN / Region, Cell class and subclass

MYADM TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

5.53e-071991578ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCellmLN-ILC|mLN / Region, Cell class and subclass

MYADM TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

5.53e-071991578d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCellmLN-(3)_ILC|mLN / shred on region, Cell_type, and subtype

MYADM TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

5.53e-07199157800e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCellmLN-(3)_ILC-(30)_ILC|mLN / shred on region, Cell_type, and subtype

MYADM TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

5.53e-07199157833ac6d77099076df01299be429f4ba96f2f34cc1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VSIG2 AQP11 MYRIP BPIFB1 PIGV PTGFR CLCA1

2.76e-061731577e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HK3 SIGLEC8 SLCO2B1 ITPR2 CFD A4GNT GAA

2.87e-061741577d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASIC1 AOX1 SLC22A12 SLC17A1 AGMO CSMD1 TMEM82

3.09e-0617615771595dbeee336a81e581325d63208ec6262664ee9
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF25 TNFRSF18 FRY ARHGEF7 CYP26C1 SLC4A10 KIT

4.30e-0618515777d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC3 DDR2 SST SSTR1 ADRA1D EGFR KIT

4.45e-061861577310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAQR5 ANO5 SST OXTR KLHL14 NPAS1

4.75e-061221576eae9d94f8510ac0f434942451d55c7260977b178
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYRIP AQP1 ITPR2 COL23A1 TMTC1 SULF2 CSMD1

4.95e-0618915777346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC3 DDR2 SST SSTR1 ADRA1D EGFR KIT

4.95e-061891577f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

MYADM TNFRSF25 MYRIP TNFRSF18 CYP26C1 SLC4A10 KIT

5.12e-0619015770c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC3 DDR2 SST PTGFR ADRA1D EGFR KIT

5.30e-061911577fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

TNFRSF25 MYRIP TNFRSF18 FRY CYP26C1 SLC4A10 KIT

5.49e-061921577e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASIC1 AOX1 AQP1 SLC22A12 INSC CSMD1 TMEM82

5.49e-0619215773e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell15-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

VSIG2 DSP GGT6 AGR3 CLDN6 CLDN9 KRTCAP3

6.07e-061951577cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCellwk_15-18-Epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL2A1 VSIG2 DSP CLDN6 CLDN9 KRTCAP3 MAP3K21

6.71e-06198157712bbe77c3d68bf1e545949dbb1eb49ed3641de3d
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LDLRAD1 VSIG2 DSP ABCA13 BPIFB1 AGR3 KRTCAP3

7.16e-06200157721d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC3 DDR2 SST ADRA1D CDH20 EGFR KIT

7.16e-062001577862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellSigmoid-ILC|Sigmoid / Region, Cell class and subclass

TNFRSF25 PTGER1 FRY CDH20 ARHGEF7 SLC4A10 KIT

7.16e-062001577dfb06821f1019833f5d81f9c93808219b5fef407
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC3 DDR2 SST ADRA1D CDH20 EGFR KIT

7.16e-062001577a91345f268f13170c27309333603eb82400c9947
ToppCellLung_Parenchyma-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LDLRAD1 VSIG2 DSP ABCA13 BPIFB1 AGR3 KRTCAP3

7.16e-06200157733658d5d09e2eaff60f4dd88837d4252328eab63
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

TNFRSF25 PTGER1 FRY CDH20 ARHGEF7 SLC4A10 KIT

7.16e-062001577a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-(3)_ILC-(30)_ILC|Sigmoid / shred on region, Cell_type, and subtype

TNFRSF25 PTGER1 FRY CDH20 ARHGEF7 SLC4A10 KIT

7.16e-062001577c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCellParenchyma_COVID-19-Epithelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LDLRAD1 VSIG2 DSP ABCA13 BPIFB1 AGR3 KRTCAP3

7.16e-062001577d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCell(3)_ILC|World / shred on Cell_type and subtype

TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

7.16e-06200157703554b3f323785b1e0b48fa32de0d92065dd798e
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

TNFRSF25 PTGER1 FRY CDH20 ARHGEF7 SLC4A10 KIT

7.16e-0620015774ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC3 DDR2 SST ADRA1D CDH20 EGFR KIT

7.16e-062001577d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell(30)_ILC|World / shred on Cell_type and subtype

TNFRSF25 TNFRSF18 FRY CYP26C1 SLC4A10 CTNNB1 KIT

8.15e-062041577bd9fbd278c05e396463704d711b60d47699e3c09
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DRD1 TRPC3 GRM4 CCDC88B TMTC1 PEAK1

1.49e-051491576558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ASIC1 CDH20 EGFR SLC17A1 KIT NPAS1

1.73e-0515315769c6fce56300ba5053efda59a438d63a808c497c0
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

FAM86B1 TNFRSF18 SLC26A1 COL23A1 INSC NPAS1

1.80e-051541576187b9d4eb0e98c506034735601ead480ff00bd57
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAQR5 ANO5 SST OXTR KLHL14 NPAS1

1.87e-0515515765c7b68b59244525e3714806c205a57a2daebf423
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 AQP11 SLC26A1 LIPC EGFR AGMO

1.94e-051561576e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO5 SST SSTR1 GRM4 OXTR PCDH8

2.31e-051611576bf70be1de418615b5442ec684552551edaf1f072
ToppCellInfluenza_Severe-NK_CD56bright|World / Disease group and Cell class

FAM86B1 TNFRSF18 COL23A1 INSC PKN3 NPAS1

2.31e-051611576de802ff96b52d28550a7854fc915f813c76ea271
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL2A1 ABCA13 BPIFB1 SST ADRA1D INSC

2.31e-051611576bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO5 SST SSTR1 OXTR KLHL14 NPAS1

2.31e-051611576dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLDN6 CLDN9 AATK CDH20 INSC CSMD1

2.57e-0516415763caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM GGT6 BCAR1 AQP1 ARHGEF7 PKN3

2.57e-0516415765ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-ILC3|Lung / Manually curated celltypes from each tissue

TNFRSF25 TNFRSF18 CLDN9 COL23A1 CYP26C1 KIT

2.84e-0516715760614d077b47a87f726068615548d0b0a216627be
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ANO5 SST OXTR KLHL14 GAA

2.93e-051011575cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 VSIG2 BPIFB1 AHCYL2 A4GNT TLCD3A

3.04e-051691576a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF25 TNFRSF18 IL22 CYP26C1 SLC4A10 KIT

3.04e-051691576d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 SSC5D GUF1 AGMO VSIG8 OCSTAMP

3.14e-0517015768d3c51364a332020810836e2055c60893c10d7f3
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ASIC1 CDH20 EGFR KIT PCDH8 NPAS1

3.24e-0517115765efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF25 TNFRSF18 IL22 CYP26C1 SLC4A10 KIT

3.24e-0517115766ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ASIC1 CDH20 EGFR KIT PCDH8 NPAS1

3.35e-0517215767e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TMC7 SSTR1 AQP1 TMTC1 FRY PKN3

3.46e-051731576ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

TMC7 SSTR1 AQP1 TMTC1 FRY PKN3

3.46e-05173157622200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 MYRIP CFD SULF2 SLC4A10 GAA

3.58e-051741576cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BPIFC TGM6 LTB4R2 ADRA1D

3.66e-05531574a58b0b1c9991cfebf20e206a129b79f494785138
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BPIFC TGM6 LTB4R2 ADRA1D

3.66e-05531574e90685a7c6ef223783b1c1a6b1896fd566449422
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BPIFC TGM6 LTB4R2 ADRA1D

3.66e-055315745ad1a5c5c9a1dc66dd7e6de6edbee0176678966c
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 SSC5D GUF1 AGMO VSIG8 OCSTAMP

3.93e-0517715764a697866ed542d3201714234cee03451adf1dcc9
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

TMC7 SSTR1 AQP1 TMTC1 FRY PKN3

4.06e-051781576e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TMC7 SSTR1 AQP1 TMTC1 FRY PKN3

4.06e-051781576363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SIGLEC8 STXBP5 PAQR5 CLDN9 FRY KIT

4.19e-051791576810972561d1ae5a68389b54ceeac7a49890513a4
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMC7 SSTR1 AQP1 FRY CSMD1 PKN3

4.19e-051791576d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VSIG2 DSP AGR3 ADCY5 CFD KRTCAP3

4.32e-0518015768ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP ADCY5 ITPR2 EGFR CYP26C1 KIT

4.46e-05181157640df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP ADCY5 ITPR2 EGFR CYP26C1 KIT

4.46e-0518115762b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP ADCY5 ITPR2 EGFR CYP26C1 KIT

4.46e-0518115766aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP ADCY5 ITPR2 EGFR CYP26C1 KIT

4.46e-05181157640d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VSIG2 DSP AGR3 ADCY5 CFD KRTCAP3

4.60e-051821576e98ca9df33a1a81fc83ecf73d5141a14f2bc985c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 SLC22A12 SLC17A1 AGMO CSMD1 TMEM82

4.60e-0518215764a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VSIG2 BPIFB1 AGR3 PTGFR CLCA1 CST2

4.60e-05182157694e70746e35a3062015d4b83ee545f4f84f47420
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

TNFRSF25 MYRIP TNFRSF18 CYP26C1 SLC4A10 KIT

4.88e-051841576d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

TNFRSF25 MYRIP TNFRSF18 CYP26C1 SLC4A10 KIT

4.88e-051841576479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASIC1 PTGFR EGFR KIT PCDH8 NPAS1

5.03e-051851576cefd81adb480c027545a5c78dcd05669783717f4
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FAM120B PAQR5 SSTR1 AATK EGFR VSIG8

5.03e-051851576b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FAM120B PAQR5 SSTR1 AATK EGFR VSIG8

5.03e-051851576d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 MYADM AHCYL1 DSP JMJD1C EGFR

5.03e-051851576eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

VSIG2 DSP ABCA13 BPIFB1 AGR3 KRTCAP3

5.19e-051861576d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 ASIC1 TRPC3 ADCY5 ADRA1D SLC4A10

5.34e-05187157659313a47a6012b2413d7d3673bb05fb7e49fd88f
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 ASIC1 TRPC3 ADCY5 ADRA1D SLC4A10

5.34e-0518715762591fe1552cd10925ad1d8d1f062a057ce6bdad9
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAQR5 AGR3 CLDN6 EGFR KRTCAP3 TMEM82

5.34e-0518715768e7ac5808bb292101e33d70616ae784b951e4bf0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SST GRM4 OXTR KLHL14 NPAS1

5.47e-051151575ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC3 DDR2 SST ADRA1D EGFR KIT

5.50e-0518815760501a8aa850bd2e347020abd1cac4d8075738189
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DRD1 TRPC3 ADCY5 TMTC1 FRY CSMD1

5.67e-0518915767fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

MYRIP SSTR1 AQP1 TMTC1 CSMD1 PKN3

5.67e-051891576fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DRD1 TRPC3 ADCY5 TMTC1 FRY CSMD1

5.67e-05189157606b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCelldroplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 SLCO2B1 TNFRSF18 ITPR2 COL23A1 KRTCAP3

5.83e-051901576c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASIC1 PTGFR EGFR KIT PCDH8 NPAS1

6.01e-051911576764c3a8829ae1253a0790744138266e81fc075ec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC3 DDR2 SST ADRA1D EGFR KIT

6.01e-0519115767b386512284dfaa0e95358b28ee82632ee965e64
ToppCellILEUM-non-inflamed-(6)_ILC3|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TNFRSF25 TNFRSF18 CYP26C1 SLC4A10 CTNNB1 KIT

6.01e-0519115766eaf72b41084404bee0db04e4605db745a74995f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC3 ADCY5 TMTC1 FRY ARHGEF7 CSMD1

6.18e-051921576bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HK3 SLCO2B1 CEACAM4 FCAR OR52K2 GAA

6.18e-0519215765ea1a8119012eb8bc3100b739a0430377a8ac534
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC3 ADCY5 TMTC1 FRY ARHGEF7 CSMD1

6.18e-051921576b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

VSIG2 DSP ABCA13 BPIFB1 AGR3 KRTCAP3

6.18e-05192157693b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL2A1 DSP CLDN6 CLDN9 FRY MAP3K21

6.18e-051921576b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

VSIG2 GGT6 PAQR5 AQP1 CLDN9 MAP3K21

6.36e-0519315769152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL2A1 VSIG2 DSP CLDN6 FRY MAP3K21

6.55e-051941576c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP AGR3 CLDN6 CLDN9 FRY MAP3K21

6.55e-0519415767b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCellILEUM-inflamed-(6)_ILC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TNFRSF25 TNFRSF18 CYP26C1 SLC4A10 CTNNB1 KIT

6.55e-0519415764d51d49366c34ff1241770b4acc0167a43b3155a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMC7 AQP1 TMTC1 AATK CTNNB1 PKN3

6.74e-0519515766bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC4A8 VSIG2 ABCA13 BPIFB1 PTGFR CFD

6.74e-0519515762a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
Diseasecleft lip

DRD1 COL23A1 SSC5D FRY LIPC AGMO CSMD1 ABCC10

9.37e-052841478EFO_0003959
Diseasekidney failure (is_implicated_in)

DRD1 MTHFR

1.47e-0441472DOID:1074 (is_implicated_in)
Diseasevenous thromboembolism, response to surgery

DRD1 CSMD1

1.47e-0441472EFO_0004286, EFO_0009951
DiseasePancreatic Neoplasm

BCAR1 SST SSTR1 EGFR CTNNB1

1.48e-041001475C0030297
DiseaseMalignant neoplasm of pancreas

BCAR1 SST SSTR1 EGFR CTNNB1

1.62e-041021475C0346647
DiseaseInsulin Resistance

SREBF2 LIPC STS EGFR

2.32e-04601474C0021655
DiseaseInsulin Sensitivity

SREBF2 LIPC STS EGFR

2.32e-04601474C0920563
Diseaseeye disease (is_implicated_in)

COL2A1 MTHFR

2.44e-0451472DOID:5614 (is_implicated_in)
DiseaseHyperphosphatasia-intellectual disability syndrome

PIGV PIGO

3.65e-0461472cv:C1855923
DiseaseHyperphosphatasia with Mental Retardation

PIGV PIGO

5.09e-0471472C1855923
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

AOX1 ITPR2 MTHFR

5.40e-04321473DOID:332 (is_implicated_in)
Diseasecervical cancer

EGFR MTHFR CTNNB1

6.47e-04341473C4048328
Diseasebreast cancer anti-estrogen resistance protein 3 measurement

BCAR1 JMJD1C

6.77e-0481472EFO_0008040
DiseaseUterine Cervical Neoplasm

EGFR MTHFR CTNNB1

7.05e-04351473C0007873
DiseaseAutosomal Recessive Polycystic Kidney Disease

AQP1 EGFR

8.67e-0491472C0085548
Diseasehypertension (biomarker_via_orthology)

SST AQP1 ADCY5 STS OXTR EGFR

9.96e-042271476DOID:10763 (biomarker_via_orthology)
DiseaseNon-Small Cell Lung Carcinoma

TMEM135 OXTR EGFR SLC22A10 KIT

1.13e-031561475C0007131
Diseasecolorectal cancer, endometrial neoplasm

GMCL1 TMTC1 AOPEP

1.21e-03421473EFO_0004230, MONDO_0005575
DiseaseEndometrioma

SST PTGFR CFD SULF2 EGFR

1.30e-031611475C0269102
DiseaseEndometriosis

SST PTGFR CFD SULF2 EGFR

1.30e-031611475C0014175
Diseasedickkopf‐related protein 1 measurement

GP6 JMJD1C

1.57e-03121472EFO_0010620
DiseaseSchizophrenia

DRD1 ABCA13 SREBF2 SST GRM4 TYR OXTR MTHFR CTNNB1 CSMD1 PCDH8 NPAS1

1.61e-0388314712C0036341
Diseasehypothyroidism (implicated_via_orthology)

COL2A1 LIPC

1.85e-03131472DOID:1459 (implicated_via_orthology)
Diseasegastric ulcer (implicated_via_orthology)

PTGER1 OXTR

2.16e-03141472DOID:10808 (implicated_via_orthology)
Diseasenephroblastoma (is_implicated_in)

MTHFR CTNNB1

2.16e-03141472DOID:2154 (is_implicated_in)
Diseaseresponse to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin

VSIG2 CSMD1

2.16e-03141472EFO_0005400, GO_0036275, GO_1902518, GO_1902520
DiseaseS-7-hydroxywarfarin measurement

TGM6 AQP1 SLC35G4 CSMD1

2.27e-031101474EFO_0803329
Diseaselysophosphatidylethanolamine 18:0 measurement

TMTC1 LIPC

2.48e-03151472EFO_0010367
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A10

2.48e-03151472DOID:2355 (implicated_via_orthology)
Diseaseatrial fibrillation

JMJD1C ITPR2 GMCL1 SLC9B1 SULF2 MTHFR AOPEP

2.66e-033711477EFO_0000275
DiseaseBarrett Epithelium

SST SLC9A1

2.83e-03161472C1258085
DiseaseBarrett Esophagus

SST SLC9A1

2.83e-03161472C0004763
DiseaseMalignant neoplasm of breast

HK3 SLCO2B1 SREBF2 MFSD9 BCAR1 EPG5 SULF2 CDH20 EGFR MTHFR CTNNB1 KIT PCDH8

2.85e-03107414713C0006142
DiseaseHypertrophic Cardiomyopathy

DSP SLC9A1 GAA

2.91e-03571473C0007194
Diseasealcohol use disorder (implicated_via_orthology)

DRD1 SREBF2 JMJD1C ADRA1D EGFR

3.00e-031951475DOID:1574 (implicated_via_orthology)
DiseaseAntibody Deficiency Syndrome

EPG5 CFD

3.19e-03171472C0003257
Diseasefasting blood glucose measurement

JMJD1C LIN9 ADCY5 CLCA1 AGMO CSMD1

3.24e-032871476EFO_0004465
DiseaseAdrenocortical carcinoma

EGFR CTNNB1

3.58e-03181472C0206686
DiseaseMalignant neoplasm of endometrium

EGFR CTNNB1

3.58e-03181472C0007103
DiseaseCarcinoma in situ of endometrium

EGFR CTNNB1

3.58e-03181472C0346191
DiseaseHypercholesterolemia, Familial

SREBF2 LIPC

3.58e-03181472C0020445
Diseasesexual dimorphism measurement

MRGPRD ASIC1 VPS33A GRM4 ZZEF1 JMJD1C SSC5D LIPC SLC17A1 AOPEP PKD1 CTNNB1 NPAS1

3.65e-03110614713EFO_0021796
Diseasetriglycerides in small HDL measurement

JMJD1C LIPC CYP26C1

3.70e-03621473EFO_0022158
DiseaseAdenocarcinoma of lung (disorder)

DDR2 SCYL2 AATK EGFR CTNNB1

3.79e-032061475C0152013
DiseaseMalignant Neoplasms

SST EGFR CTNNB1 KIT

3.91e-031281474C0006826
Diseaseinflammatory bowel disease (is_implicated_in)

EGFR MTHFR

3.99e-03191472DOID:0050589 (is_implicated_in)
Diseasediabetes mellitus (biomarker_via_orthology)

AQP1 SLC22A12

3.99e-03191472DOID:9351 (biomarker_via_orthology)
Diseasecarcinoma (implicated_via_orthology)

EGFR CTNNB1 KIT

4.04e-03641473DOID:305 (implicated_via_orthology)
DiseaseCardiomyopathies

DSP ADCY5 EPG5 GAA

4.13e-031301474C0878544
Diseaseend stage renal disease (implicated_via_orthology)

DRD1 LIPC

4.42e-03201472DOID:783 (implicated_via_orthology)
DiseaseLeft Ventricle Remodeling

SLC9A1 CTNNB1

4.86e-03211472C0600520
DiseaseVentricular Remodeling

SLC9A1 CTNNB1

4.86e-03211472C0600519
Diseaseleft atrial function

DSP AOPEP

4.86e-03211472EFO_0004294
Diseasegestational age, birth measurement

COL2A1 INSC

4.86e-03211472EFO_0005112, EFO_0006921
Diseasedocosahexaenoic acid to total fatty acids percentage

JMJD1C LIPC

4.86e-03211472EFO_0022262

Protein segments in the cluster

PeptideGeneStartEntry
AVVSAVTLLRLLLNC

URB2

1266

Q14146
LPLLTAACQSLASVR

EPG5

2306

Q9HCE0
LVAALVCFLLLSRTG

CEACAM4

166

O75871
LTGSCLNFIVILILN

ANO5

516

Q75V66
TFTLLCGLLAATLIQ

BPIFB1

6

Q8TDL5
LEGVLRLLLGASVQC

CCDC88B

136

A6NC98
LLVLCARLLTAAKGQ

CSMD1

16

Q96PZ7
SNLLCDLLRGIVATT

BCAR1

816

P56945
DTAALSQVTLLLRVC

AGMO

356

Q6ZNB7
VARVGSVAIKLCNLL

SMPD1

111

P17405
RVAQCLTSLLLLAEP

BTBD6

11

Q96KE9
LLCVLSQLEGLAQAL

GOT1L1

271

Q8NHS2
ALGLCLLLVTVSSNL

AGR3

6

Q8TD06
AITFSLISLQLLGIC

GRM4

701

Q14833
QLSLSVTLLLVCGFL

A4GNT

6

Q9UNA3
LGLLLSCQISIFRAL

AQP1

81

P29972
GSILVNLSSCVALNR

ABCA13

3421

Q86UQ4
AVREGTILILANLCA

ARMC5

296

Q96C12
TILILANLCAQGLIR

ARMC5

301

Q96C12
LQASLKDGVVLCRLL

ARHGEF7

31

Q14155
VCLTGACQETLLRLI

AOPEP

406

Q8N6M6
SLLILSTLLGNTLVC

DRD1

31

P21728
STLLGNTLVCAAVIR

DRD1

36

P21728
AVLSLGACCLALLQI

ADCY5

201

O95622
SLATLIGLCLRVKLQ

CIAO2A

91

Q9H5X1
DIACRLILNEVSLLG

AOX1

491

Q06278
VLLTLLVAAVLRCQG

COL2A1

11

P02458
VVAILAAACLLQLDG

GMCL1

181

Q96IK5
LGNLLIILAAISDSC

OR7A2P

41

Q8NGA2
CSAGQKVLASLIIRL

RAD50

1201

Q92878
ILTSAILLGSRVSCR

GSG1L2

136

A8MUP6
VNRGAIILSSLLQSC

PUM3

596

Q15397
NGRSIILTAVLALIL

ITPR2

2391

Q14571
TLTALICGFIIKLRN

INPP4A

681

Q96PE3
VSRSLSACQGVLLVV

GUF1

151

Q8N442
VFRLSLGLTILACES

NPAS1

306

Q99742
AGAILLCIIFSLSNI

PAQR5

296

Q9NXK6
RLAVLVLLGAAACAA

CFD

6

P00746
GVNSLCTLLRAVLFA

ABCC10

976

Q5T3U5
CTLLRAVLFAAGTLQ

ABCC10

981

Q5T3U5
ELRTVNCLLVGAIAI

NOL9

631

Q5SY16
GNLLIFLVVCLDSRL

OR6N1

41

Q8NGY5
LIKATVGLIRNLALC

CTNNB1

506

P35222
LAVSLCQELLASGLV

MTHFR

301

P42898
IVSLVGVLQRLAACR

FAM86B2

256

P0C5J1
RLTAILLQIKCLAEG

LIN9

466

Q5TKA1
LALLVGLLAAAETQC

NCDN

196

Q9UBB6
LCVLLLLLRVQTGSS

KIT

11

P10721
VGRRSSLLACILLSA

MFSD9

106

Q8NBP5
SNTRILIGCLVAIIF

DDR2

396

Q16832
RTCTLIQFLGDAIVL

JMJD1C

2446

Q15652
ACARLAEASLLLVTL

GDF1

226

P27539
AGSRAVSALCLLLSV

COL23A1

31

Q86Y22
AIVSLVGVLQRLAAC

FAM86B1

221

Q8N7N1
TKGNLVRICLGAVIL

GP6

266

Q9HCN6
TTLLCLVLCLGQRIQ

FCAR

6

P24071
SLLCNAITGITLLRV

PTGFR

216

P43088
LRSVLLCGIEAQACI

ISOC2

101

Q96AB3
IRANSICGLIDLILT

OR51F1

201

A6NGY5
IANSGLLSLVCFLVL

OR4Q3

201

Q8NH05
LAGSCTLLLAAIIAI

PCDH8

756

O95206
GLVALLAALVCNTLS

PTGER1

211

P34995
LAALVCNTLSGLALL

PTGER1

216

P34995
RQVCLLLLQLCSGLE

PEAK1

1491

Q9H792
VGLSLLTAISTQRCL

MRGPRD

111

Q8TDS7
LLVLCIFIQSSALGQ

LIPC

11

P11150
VVCLVNIFLTGRLSS

LRP3

21

O75074
LGLLRLLQLVSTCVA

MYADM

36

Q96S97
LAAIAILLNLGECTN

MYADM

216

Q96S97
LRLVQLFCLLGAIST

LYPD4

6

Q6UWN0
GACLSASLLLLLATV

LDLRAD1

36

Q5T700
LSASLVRILCEQIAS

NLRP2

711

Q9NX02
LLALSGNACVLLALR

OXTR

51

P30559
GAALVTAVACRLAQL

HK3

906

P52790
SRGLEICLNSQVLLV

CYP2U1

256

Q7Z449
RLLGICLTSTVQLIT

EGFR

776

P00533
VLQGCSSIGLRLVLE

KLHL14

126

Q9P2G3
LVILGQRLVCSLSLN

BPIFC

391

Q8NFQ6
SLSRGALIAILACIF

CDH20

616

Q9HBT6
VAALLLLAVGCSLAV

GGT6

61

Q6P531
SLCTVRALLQAILQT

DSP

766

P15924
ILLGLRLDEAQCATL

CYP26C1

196

Q6V0L0
ARGSIQLTVLLCELL

ELMO3

401

Q96BJ8
RLLAVCALVSLATAA

GAA

11

P10253
AVLVACLAALRRLAG

INSC

531

Q1MX18
VGLRLAACLLNVSEA

FTCDNL1

6

E5RQL4
NLRITLQFLISLCGV

FRY

1451

Q5TBA9
CTLLLLLATQAVALA

CST2

6

P09228
ASLLLAGLCILANTL

SLC22A12

411

Q96S37
LVRGLTTLVLVNSAC

FAM120B

776

Q96EK7
VNLLLSVACSLGLLL

KRTCAP3

101

Q53RY4
LLVVARCLSLSAGQT

MCMBP

596

Q9BTE3
ACALRLLAATEQLTV

PKD1

766

P98161
LQVRLLGCEQLLTAV

PKN3

281

Q6P5Z2
ILAVRCGSASIVSLL

POTEA

236

Q6S8J7
GNLLIVLAICSDVRL

OR1A1

41

Q9P1Q5
GNTALILVCCLDSRL

OR2G6

41

Q5TZ20
LLGNCTLLLIIQADA

OR52K2

41

Q8NGK3
VLGSIAIITARNLSC

SLC35G5

316

Q96KT7
GALLCRLVLSVDAVN

SSTR1

126

P30872
VLLAEGRLLNLSCST

AHCYL2

516

Q96HN2
ALTSIVVLAAGCALR

PRR23A

56

A6NEV1
IASLRNVCISLLAGI

SLC9B1P1

51

A6NJY1
GISVSTLSLALCVRI

SLC9B1P1

166

A6NJY1
GLTLLLCAVLLSLAS

SEL1L

6

Q9UBV2
LRNCLLTADLTVKIG

AATK

256

Q6ZMQ8
CTVLLASVALGLDLR

MAP3K21

726

Q5TCX8
LTGLLSLQRCLAVTR

LTB4R2

111

Q9NPC1
LLAEGRLLNLSCSTV

AHCYL1

436

O43865
GAVALIVRCLALLTL

SLC22A10

386

Q63ZE4
ALTSIVVLAAGCALR

PRR23B

56

Q6ZRT6
IGFALCLSSVLSLLI

SLC17A1

111

Q14916
VQLLRSSVCLATALN

SMG1

1291

Q96Q15
QIVGVTLLTLAALNC

STS

191

P08842
LSVLEGQSLRLVCAV

SIGLEC8

271

Q9NYZ4
SLAVRVNSLVCLGKI

SCYL2

501

Q6P3W7
GQLLTQLLLCASLAA

OCSTAMP

46

Q9BR26
ELLLQIRCLVSGLSS

SCFD2

211

Q8WU76
LFELRSCLINGTVLL

SLC4A8

166

Q2Y0W8
LATSCLLLLALLVQG

IL22

16

Q9GZX6
CLLAALVGIQAVERL

SSC5D

6

A1L4H1
LCVSSLVLLVRILCG

MRGPRX4

191

Q96LA9
LRGDIVALSNSICLA

STXBP5

946

Q5T5C0
VAGNLLVILSVACNR

ADRA1D

111

P25100
TGAVRLLAQLVSALC

AQP11

116

Q8NBQ7
LGSLAVLLCVCTERV

ASIC1

51

P78348
RALCVIALLVALFGL

CLDN6

81

P56747
DLQAARALCVIALLL

CLDN9

76

O95484
TFSLLQIGQRIVCLV

CLCA1

296

A8K7I4
RGLLSLRSCLLISVA

PIGV

106

Q9NUD9
VLGSIAIITARNLIC

SLC35G4

316

P0C7Q5
CSLGLSREALIALLV

TMEM210

36

A6NLX4
TSICIGILLRSAELA

UHRF1BP1L

856

A0JNW5
LSVCLICTRLLQEGI

LINC02912

46

Q8N9X5
LVCLSPALLSAVRIN

VSIG8

11

P0DPA2
LRIVSCGNAIIAELL

WASHC5

16

Q12768
NRCGATTLIVSTVLL

TMTC1

436

Q8IUR5
VSILLCVRALQLRSS

RLF

371

Q13129
VLACVIVVSLRGALR

SLC26A1

441

Q9H2B4
GSVICFALVLAVLRQ

SLCO2B1

661

O94956
GILTLATFLSCRILL

TLCD3A

181

Q8TBR7
SLFELRSCILNGTVL

SLC4A10

166

Q6U841
VQLLTCDLLLSLRTA

SREBF2

971

Q12772
AVLTALLAGLVSLLC

TYR

486

P14679
TITTLRNGEVLLFCI

TMEM135

146

Q86UB9
STLLFCLIARVLGVL

SLC9A1

416

P19634
NSGVSLLVLALCLSL

PPP1R3F

781

Q6ZSY5
SIRNVCISLLAGIVL

SLC9B1

286

Q4ZJI4
NIVGISVATLSLALC

SLC9B1

396

Q4ZJI4
CLVGVRTLLDLCQIQ

TMEM82

301

A0PJX8
RGCAAVAAALLLVLL

TNFRSF25

6

Q93038
LAVAACVLLLTSAQL

TNFRSF18

171

Q9Y5U5
TLLTFCTNGVLLRTL

YTHDC2

286

Q9H6S0
SVCGATLLLRTLQFI

ZZEF1

726

O43149
GIQILACALAASILR

PIGO

1021

Q8TEQ8
AVLLLCVLLSRASGA

TMEM218

21

A2RU14
VLRLVCLQSVCNSGL

VPS33A

406

Q96AX1
GLLVLCRIASNVLNT

GTF3C1

1271

Q12789
LGVLLLSVAAFCLVR

VSIG2

251

Q96IQ7
LQCALAALSIVLALG

SST

6

P61278
LVLCLLSATVFSLLG

SULF2

6

Q8IWU5
LCTVLRCLGIATRVV

TGM6

281

O95932
LSGLREQTIAIKCLV

TRPC3

326

Q13507
LRLFLNCIVLAVLGA

TMC7

361

Q7Z402
RISALTIAGLNIAPC

MYRIP

761

Q8NFW9