Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF1669

FAM83D FAM83B

2.81e-048602IPR012461
DomainDUF1669

FAM83D FAM83B

2.81e-048602PF07894
DomainIg_I-set

LRIG3 MYPN FGFR1 PALLD MYBPC1

3.59e-04190605IPR013098
DomainI-set

LRIG3 MYPN FGFR1 PALLD MYBPC1

3.59e-04190605PF07679
DomainIGc2

LRIG3 MYPN FGFR1 PALLD MYBPC1

9.40e-04235605SM00408
DomainIg_sub2

LRIG3 MYPN FGFR1 PALLD MYBPC1

9.40e-04235605IPR003598
DomainDH_1

PLEKHG4B AKAP13 PLEKHG5

1.09e-0363603PS00741
Domain-

IFNGR1 MST1R LRIG3 MYPN FGFR1 TRIM36 PALLD MYBPC1

1.21e-036636082.60.40.10
DomainRhoGEF

PLEKHG4B AKAP13 PLEKHG5

1.36e-0368603SM00325
DomainRhoGEF

PLEKHG4B AKAP13 PLEKHG5

1.48e-0370603PF00621
DomainDH_2

PLEKHG4B AKAP13 PLEKHG5

1.48e-0370603PS50010
DomainDH-domain

PLEKHG4B AKAP13 PLEKHG5

1.54e-0371603IPR000219
Domain-

PLEKHG4B AKAP13 PLEKHG5

1.54e-03716031.20.900.10
DomainIg-like_fold

IFNGR1 MST1R LRIG3 MYPN FGFR1 TRIM36 PALLD MYBPC1

1.81e-03706608IPR013783
DomainRING

RNF7 ATRX TRIM36 RNF43 RNF111

2.95e-03305605SM00184
DomainZnf_RING

RNF7 ATRX TRIM36 RNF43 RNF111

3.91e-03326605IPR001841
DomainSNF2_N

TTF2 ATRX

4.73e-0332602IPR000330
DomainSNF2_N

TTF2 ATRX

4.73e-0332602PF00176
Domainzf-C3HC4

RNF7 TRIM36 RNF43 RNF111

5.72e-03223604PF00097
Domain-

PLEKHG4B RABGAP1L AKAP13 PLEKHG5 RGS3

8.34e-033916052.30.29.30
DomainPDZ

MYO18A SIPA1L2 RGS3

1.05e-02141603PF00595
DomainIG

LRIG3 MYPN FGFR1 PALLD MYBPC1

1.12e-02421605SM00409
DomainIg_sub

LRIG3 MYPN FGFR1 PALLD MYBPC1

1.12e-02421605IPR003599
DomainPH_dom-like

PLEKHG4B RABGAP1L AKAP13 PLEKHG5 RGS3

1.18e-02426605IPR011993
DomainPDZ

MYO18A SIPA1L2 RGS3

1.20e-02148603SM00228
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FSIP2 RABGAP1L KCTD8 NAV2 AKAP13 ITPRID2 SIPA1L2 AKAP1 VIRMA PALLD PABIR2 CFAP97 FAM83B

2.12e-09861601336931259
Pubmed

MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1.

FGFR1 MUC4

2.93e-06260222791819
Pubmed

The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity.

IFNGR1 MST1R

2.93e-06260218684919
Pubmed

ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity.

ACD ATRX

8.77e-06360231895940
Pubmed

mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes.

AKAP6 AKAP1

8.77e-06360210413680
Pubmed

Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heart.

AKAP13 AKAP1

8.77e-06360223045525
Pubmed

Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.

AKAP6 AKAP13

2.92e-05560223071553
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR1 ACVR1

6.11e-0576028959336
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

MYPN PALLD

8.14e-05860211309420
Pubmed

Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring.

AKAP6 AKAP13

1.05e-04960212672969
Pubmed

Anchoring and scaffold proteins for kinases and phosphatases.

AKAP6 AKAP1

1.05e-0496029238861
Pubmed

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

MST1R FGFR1

1.05e-04960225512530
Pubmed

AKAP mediated signal transduction.

AKAP6 AKAP1

1.31e-041060211807172
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

NAV2 SIPA1L2 VIRMA CFAP97

1.45e-0415360410718198
Pubmed

The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.

FAM83D FAM83B

1.59e-041160229789297
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

PLEKHG4B LENG8 ITPRID2

1.80e-046360311572484
Pubmed

A human MAP kinase interactome.

LENG8 MYO18A NAV2 AKAP13 ITPRID2 RNF111

1.91e-0448660620936779
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

FSIP2 ATRX AKAP13 RYR3

2.07e-0416860430631154
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 NFE2L1 MYPN AKAP1 PALLD MYBPC1

2.15e-0449760623414517
Pubmed

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.

AKAP13 PCDH9

2.26e-041360221844884
Pubmed

Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.

LRIG3 PRICKLE1

2.63e-041460220445134
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 LRIG3 TELO2 NAV2 PLEKHG5 CFAP97

3.01e-0452960614621295
Pubmed

Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.

MYPN PALLD

3.46e-041660225987543
Pubmed

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

AKAP6 IFNGR1 ACVR1 AKAP1

3.52e-0419360420677014
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

MYPN AKAP13 ITPRID2 VIRMA FAM83B

4.01e-0436160530344098
Pubmed

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

RNF7 DCUN1D4

4.40e-041860226906416
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

AKAP6 ATRX MYBPC1

5.50e-049260315840729
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

LRIG3 SNPH RABGAP1L SIPA1L2 VIRMA

6.90e-0440760512693553
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

LENG8 ITPRID2 SIPA1L2 VIRMA

8.21e-0424260434011540
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ATRX FAM83D FGFR1 ACVR1 PALLD CFAP97 RNF111

9.49e-0491060736736316
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATRX TELO2 MYO18A AKAP13 ITPRID2 SIPA1L2 AKAP1 ABHD12 FAM83B

9.64e-04148760933957083
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

WDR45 IKZF2 NFE2L1 FGFR1 PLEKHG5 FCHO1 PABIR2

1.04e-0392560728986522
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

WDR45 ATRX MYPN SKIDA1 NAV2 ZFHX2

1.07e-0367460637196079
Pubmed

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

FGFR1 ACVR1

1.07e-032860219224984
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

MST1R FGFR1

1.07e-032860218593464
Pubmed

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.

AKAP6 FGFR1

1.07e-032860224427155
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

LENG8 SIPA1L2 RNF43 FAM83B

1.12e-0326360434702444
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

TELO2 MYO18A FAM83D ITPRID2

1.13e-0326460432814769
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

IKZF2 NFE2L1 PROX2 ZFHX2 RNF43 RNF111

1.38e-0370960622988430
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

SIPA1L2 RGS3

1.68e-033560233864728
InteractionNRSN1 interactions

IFNGR1 LRIG3 FAM83D ENDOU FGFR1 ACVR1 SIPA1L2 RNF111

4.99e-08179598int:NRSN1
InteractionKCNE3 interactions

LENG8 PRICKLE1 FAM83D FGFR1 ACVR1 SIPA1L2 PCDH9 CFAP97

2.28e-06296598int:KCNE3
InteractionARHGAP21 interactions

PRICKLE1 MYO18A AKAP13 DYNLT1 TRIM36 VIRMA RNF43

3.87e-06223597int:ARHGAP21
InteractionMYPN interactions

MYPN ITPRID2 VIRMA PALLD

5.60e-0640594int:MYPN
InteractionARHGEF2 interactions

PRICKLE1 AKAP13 DYNLT1 FGFR1 TRIM36 AKAP1 VIRMA

9.55e-06256597int:ARHGEF2
InteractionCEP162 interactions

TTF2 KCTD8 MYO18A TRIM36 VIRMA PALLD

9.59e-06168596int:CEP162
InteractionYWHAH interactions

MST1R RABGAP1L NAV2 AKAP13 ITPRID2 SIPA1L2 AKAP1 PLEKHG5 VIRMA PALLD PABIR2 CFAP97 FAM83B

1.40e-0511025913int:YWHAH
InteractionSFN interactions

MST1R RABGAP1L NAV2 AKAP13 ITPRID2 SIPA1L2 VIRMA PALLD PABIR2 FAM83B

2.93e-056925910int:SFN
InteractionYWHAB interactions

MST1R NAV2 AKAP13 FGFR1 ITPRID2 SIPA1L2 PLEKHG5 VIRMA RNF43 RGS3 PABIR2 FAM83B

3.08e-0510145912int:YWHAB
InteractionCCSER2 interactions

ATRX TRIM36 VIRMA RNF43

3.93e-0565594int:CCSER2
InteractionYWHAE interactions

MST1R ACD NAV2 AKAP13 DYNLT1 ITPRID2 SIPA1L2 PLEKHG5 VIRMA RNF43 RGS3 PABIR2 FAM83B

5.51e-0512565913int:YWHAE
InteractionMAPRE3 interactions

TTF2 NAV2 TRIM36 FCHO1 CFAP97 FAM83B

5.63e-05230596int:MAPRE3
InteractionSVIL interactions

ATRX MYO18A DYNLT1 VIRMA RNF43 CFAP97

6.05e-05233596int:SVIL
InteractionSTUB1 interactions

IFNGR1 MST1R DDIAS SNPH ACD ATRX ACVR1 AKAP1 RNF43

6.38e-05608599int:STUB1
InteractionYWHAZ interactions

MST1R FSIP2 MYO18A NAV2 AKAP13 DYNLT1 ITPRID2 SIPA1L2 PLEKHG5 VIRMA RGS3 PABIR2 FAM83B

9.09e-0513195913int:YWHAZ
InteractionAPC interactions

TELO2 NAV2 AKAP13 TRIM36 VIRMA RNF43 FAM83B

1.36e-04389597int:APC
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRIG3 MYPN FGFR1 PALLD MYBPC1

2.37e-05161395593
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP6 AKAP13 AKAP1

3.26e-0529393396
GeneFamilyRing finger proteins

RNF7 TRIM36 RNF43 RNF111

2.83e-0327539458
GeneFamilyReceptor Tyrosine Kinases|CD molecules

MST1R FGFR1

3.36e-0340392321
GeneFamilyPDZ domain containing

MYO18A SIPA1L2 RGS3

4.27e-031523931220
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4B AKAP13 PLEKHG5

9.85e-03206393682
CoexpressionGSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP

IKZF2 RABGAP1L MYO18A TRIM36 DCUN1D4 RYR3

5.97e-06197606M6575
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

AKAP6 PRICKLE1 RABGAP1L MYPN PCDH9 PALLD RGS3

7.91e-0919460789812fb164065041357bb37a3c2d87028ec3de4e
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

AKAP6 RABGAP1L MYPN AKAP13 PCDH9 PALLD

1.80e-07184606ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

AKAP6 PRICKLE1 RABGAP1L MYPN PALLD RGS3

2.45e-07194606c3535f7cc0076653c72db582047cff053c322397
ToppCellfacs-BAT-Fat-3m-Lymphocytic-NK_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNGR1 GPRIN3 FCHO1 RNF43 PABIR2

2.81e-06164605cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

AKAP6 RABGAP1L MYPN PALLD RGS3

5.47e-061886056d249fe92d51a19da19ec14bb2262d394255d577
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

AKAP6 RABGAP1L MYPN AKAP13 PALLD

5.91e-0619160525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

AKAP6 RABGAP1L MYPN PALLD RGS3

5.91e-061916055d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN AKAP13 PCDH9 PALLD

6.54e-0619560575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 NFE2L1 MYPN PALLD MYBPC1

6.87e-0619760544e49943d62bfe622b40ad0460093d31540544df
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 FGFR1 PCDH9 PALLD

6.87e-061976059b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT4 ATRX ITPRID2 SIPA1L2 PLEKHG5

7.39e-06200605a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRC66 KCTD8 ZFHX2 MYBPC1

4.04e-05142604819e983688d126d89a71abc03d72525cc759a347
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

AKAP6 AKAP1 PALLD RYR3

5.41e-05153604ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDIAS ACD ABHD12 PIK3R5

5.69e-051556044559e3011514041b65c17ae4ede29da202bce14c
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

RHEX MYO18A TRIM36 RYR3

7.77e-0516860445ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRIG3 FAT4 MYPN MYBPC1

7.77e-051686042eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

8.13e-051706043f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PIK3R5 PALLD

8.13e-051706044232fe937909f93d3736988c707b8f95ce993398
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 FGFR1 PALLD

8.32e-05171604972fab891135bd755d5526cbc5a963200067b0a6
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDIAS TTF2 ABHD12 PABIR2

8.32e-05171604845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 FGFR1 PALLD

8.32e-051716042a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

AKAP6 FAM83D PALLD RYR3

8.70e-05173604a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDIAS TTF2 NAV2 PLEKHG5

8.90e-0517460472df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDIAS TTF2 NAV2 PLEKHG5

8.90e-05174604c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

FAT4 NAV2 PALLD RGS3

8.90e-05174604430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellfacs-Skin-nan-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 FGFR1 TRIM36 PALLD

9.10e-05175604f1166b567bca80dac3abe90c3dc544c831006640
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

9.30e-051766049df7a124ebafb0087da0cda133a394275d7bed81
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.04e-04181604719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.06e-04182604287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.08e-041836042902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHEX GPRIN3 PIK3R5 FCHO1

1.10e-04184604315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.10e-04184604e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.13e-04185604549eeb521c3985bff396ea0f202db21822efa51f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

AKAP6 RABGAP1L MYPN PALLD

1.13e-041856046baccb26f999145e51b91d94315bf8d4655bef31
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCTD8 SKIDA1 AKNAD1 PCDH9

1.15e-041866042fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCTD8 SKIDA1 AKNAD1 PCDH9

1.15e-04186604ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG4B IKZF2 NAV2 RNF43

1.15e-041866044e94158db52df41d71e67b02b9895a358eebee0f
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCTD8 SKIDA1 AKNAD1 PCDH9

1.15e-04186604714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MST1R NAV2 PCDH9 FAM83B

1.17e-0418760487b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MST1R NAV2 PCDH9 FAM83B

1.17e-0418760442a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MST1R NAV2 PCDH9 FAM83B

1.17e-0418760464afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ACVR1 RGS3 PABIR2

1.17e-04187604d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ACVR1 RGS3 PABIR2

1.17e-041876047b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 NAV2 PALLD RYR3

1.17e-041876043912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

AKAP6 PRICKLE1 PCDH9 RYR3

1.22e-041896043717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

AKAP6 MYPN AKAP13 PALLD

1.22e-041896040a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PRICKLE1 NAV2 PALLD

1.22e-04189604c734e5693808a0333139e87bd5be2597a9252afe
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

AKAP6 MYPN AKAP13 PALLD

1.25e-0419060493c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

AKAP6 RABGAP1L AKAP13 PALLD

1.25e-04190604de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.25e-04190604918ad5037881212008f9f69d5df5da91fd01422c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PRICKLE1 NAV2 PALLD

1.27e-04191604c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RHEX IKZF2 PCDH9 FCHO1

1.27e-0419160484452125d1b5b76974e3f9126f611eff16d45c25
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PRICKLE1 NAV2 PALLD

1.27e-04191604cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ACVR1 RGS3 PABIR2

1.30e-041926040b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellfacs-Brain_Non-Myeloid-Striatum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRIN3 ABHD12 PCDH9 RYR3

1.33e-04193604d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

GPRIN3 SIPA1L2 ABHD12 PIK3R5

1.33e-04193604cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RABGAP1L AKAP13 PIK3R5 RNF111

1.33e-04193604779276e775cb2492e8dd36436295a536084a6415
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 MYPN PCDH9 PALLD

1.33e-04193604dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

PLEKHG4B FSIP2 MUC4 PALLD

1.33e-0419360450e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPRIN3 SIPA1L2 ABHD12 PIK3R5

1.38e-041956049d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

NAV2 ITPRID2 PCDH9 FAM83B

1.41e-0419660404f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LENG8 NAV2 PCDH9 RYR3

1.41e-04196604b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ACVR1 RGS3 PABIR2

1.41e-04196604e386526332138e636aef2542c11316347a45689c
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 KCTD8 FAM83D PALLD

1.41e-041966049830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 PCDH9 PALLD

1.44e-0419760485a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RABGAP1L NAV2 AKAP1 RNF43

1.44e-041976041485933986921ff45669d9b7501c8d17050b3e97
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 PCDH9 PALLD

1.44e-04197604e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRIG3 AKAP1 MUC4 RNF43

1.44e-041976049ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRIG3 AKAP1 MUC4 RNF43

1.44e-04197604c0250509836f1be04f5e54386191d7bb1e1da652
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NAV2 FGFR1 PALLD

1.46e-04198604a860246bcea847249a78fd2e86ed8e04371060db
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 FAM83D PCDH9 RGS3

1.46e-0419860422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 ATRX ITPRID2 PLEKHG5

1.52e-04200604dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 NAV2 FGFR1 PCDH9

1.52e-04200604a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellTransverse-(2)_B_cell-(24)_B_cell_cycling|Transverse / shred on region, Cell_type, and subtype

DDIAS TTF2 PCDH9 RNF111

1.52e-04200604e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCellTransverse-B_cell-B_cell_cycling|Transverse / Region, Cell class and subclass

DDIAS TTF2 PCDH9 RNF111

1.52e-042006040e270f8019d9f22068ca426d661937262a5cd331
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 ITPRID2 PALLD RGS3

1.52e-04200604ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 NAV2 FGFR1 PCDH9

1.52e-04200604c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

FAT4 IKZF2 PALLD RGS3

1.52e-042006042281debd86e5d92e8fe0397aec9ef670800f7471
ComputationalRTK signaling.

IFNGR1 MST1R FGFR1

3.66e-0446333MODULE_259
ComputationalGenes in the cancer module 85.

IFNGR1 MST1R FGFR1

4.97e-0451333MODULE_85
ComputationalGenes in the cancer module 199.

IFNGR1 MST1R FGFR1

6.89e-0457333MODULE_199
ComputationalGrowth suppressors.

FGFR1 RGS3

6.98e-0413332MODULE_407
ComputationalGenes in the cancer module 173.

FGFR1 RGS3

1.07e-0316332MODULE_173
DiseaseMalignant Glioma

ATRX FGFR1 ACVR1

3.24e-0470563C0555198
Diseasemixed gliomas

ATRX FGFR1 ACVR1

3.24e-0470563C0259783
DiseaseGlioma

ATRX FGFR1 ACVR1

6.13e-0487563C0017638
DiseaseHepatitis

FAT4 NAV2

7.98e-0422562HP_0012115
DiseasePancreatic Neoplasm

ATRX PALLD RNF43

9.19e-04100563C0030297
Diseasepancreatic cancer (is_marker_for)

ACVR1 MUC4 PALLD

9.46e-04101563DOID:1793 (is_marker_for)
DiseaseMalignant neoplasm of pancreas

ATRX PALLD RNF43

9.73e-04102563C0346647
DiseaseCerebral Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0750935
DiseaseIntracranial Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0750936
DiseasePilocytic Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0334583
DiseaseAstrocytoma

FGFR1 ACVR1

1.03e-0325562C0004114
DiseaseJuvenile Pilocytic Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0280783
DiseaseDiffuse Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0280785
DiseaseGrade I Astrocytoma

FGFR1 ACVR1

1.03e-0325562C1704230
DiseaseSubependymal Giant Cell Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0205768
DiseaseMixed oligoastrocytoma

FGFR1 ACVR1

1.03e-0325562C0547065
DiseaseChildhood Cerebral Astrocytoma

FGFR1 ACVR1

1.03e-0325562C0338070
Diseaseglycerol measurement

FAT4 SIPA1L2

1.12e-0326562EFO_0010115
DiseaseGemistocytic astrocytoma

FGFR1 ACVR1

1.12e-0326562C0334581
DiseaseProtoplasmic astrocytoma

FGFR1 ACVR1

1.12e-0326562C0334580
DiseaseFibrillary Astrocytoma

FGFR1 ACVR1

1.12e-0326562C0334582
DiseaseAnaplastic astrocytoma

FGFR1 ACVR1

1.20e-0327562C0334579
DiseaseDNA methylation

PLEKHG4B FAT4 IKZF2 RABGAP1L GPRIN3 RNF43

1.49e-03656566GO_0006306
Diseaseblood urea nitrogen measurement

IKZF2 PRICKLE1 GPRIN3 AKAP13 FAM83B

1.66e-03452565EFO_0004741

Protein segments in the cluster

PeptideGeneStartEntry
DDHQTGSLRSCSSSD

DCUN1D4

41

Q92564
HCSDSFSTSGLEDSC

AKAP1

506

Q92667
TDCLDAGSDSHLSDS

CFAP97

186

Q9P2B7
PESSSDSDSHESFTC

FAT4

4836

Q6V0I7
EEHLACDITGSSSST

AKAP13

1461

Q12802
GDSTLADLLDHSCTS

ACVR1

176

Q04771
EEFDSDSGLSLDSSH

NFE2L1

471

Q14494
DGEETCALASHSGSS

RNF7

6

Q9UBF6
FASDTTLHCSDGEGA

RGS3

956

P49796
EHERCAAAGSSSSGS

ABHD12

11

Q8N2K0
ESAFDHEDFTGSSSL

FCHO1

441

O14526
TALHDTDASSLSTGD

MUC4

2111

Q99102
SCNELSTSSCDSHSE

KCTD8

351

Q6ZWB6
DSSGTCHIDNSSEAD

LRIG3

896

Q6UXM1
DSHSDSDSSYSGNEC

LENG8

436

Q96PV6
SSTGEAEDCHSDPSA

FSIP2

6806

Q5CZC0
AHGTDDSCDDTLSSG

FAM83B

76

Q5T0W9
TSSDHFSASECSSQG

PCDH9

986

Q9HC56
ILDSGHLSTASSSDD

MYO18A

91

Q92614
ESLCSDHEVSHSSDA

ENDOU

121

P21128
SISIAEATGSSSCHD

DDIAS

276

Q8IXT1
AEDSFGSSHDCSSGT

FAM83D

86

Q9H4H8
HGCVESSILDSSAGS

GHDC

421

Q8N2G8
SNSCLDSTDSESSHD

IKZF2

401

Q9UKS7
SDSSGFAEDSTDCLS

ITPRID2

506

P28290
SDCDSDEGSLFTLSS

LRRC66

701

Q68CR7
DCQSSSEISDHSFGD

RABGAP1L

76

Q5R372
HDGTTESNCFAFTES

RABGAP1L

206

Q5R372
ESNCFAFTESSHGSE

RABGAP1L

211

Q5R372
DLSSCSDILDGSSSS

PABIR2

196

Q7Z309
GTCSLHTTASTLDDD

PALLD

1056

Q8WX93
SHLAEACTEGERSSS

PROX2

16

Q3B8N5
CSLGEDVHASDSSDS

PRICKLE1

306

Q96MT3
SSHTGFCQSSGDEAL

ATRX

1236

P46100
STCSSGEDSVFSHEP

FGFR1

786

P11362
GLHTASSCFWDSSTD

DYNLT1

76

P63172
NSDTGHSFCSDSGTE

AKNAD1

646

Q5T1N1
ICHSSGSHTLELSDS

GPRIN3

361

Q6ZVF9
GFDTDSSCLESHSSL

IFNGR1

411

P15260
SSCLESHSSLSDSEF

IFNGR1

416

P15260
SGHDSGSEDACFDSS

TRIM36

616

Q9NQ86
HDSDTPSDSLDSSCS

RHEX

86

Q6ZWK4
HTSCESIDISLSSGG

NAV2

1431

Q8IVL1
HLGSFPESCSSDSES

SKIDA1

371

Q1XH10
HGSSSTFCSSLSSDF

RNF43

491

Q68DV7
SGESCSFESSLSSHC

SIPA1L2

436

Q9P2F8
SSEDGGHIFCTLESL

TELO2

21

Q9Y4R8
SHDSSFLCASSDKGT

WDR45

246

Q9Y484
SGVDCGTEETSLHSS

SNPH

266

O15079
CLEEHLSESTSSNAG

ACD

151

Q96AP0
SYLSLSSHDSDCGEV

AKAP6

2111

Q13023
DSQHCASDGSTETLA

PLEKHG5

746

O94827
CPDDTHFVSSSSDKS

WDR61

241

Q9GZS3
EACSLSAGDLSDSSA

ZFHX2

2021

Q9C0A1
DCLSSPSSSLHFGDS

RNF111

136

Q6ZNA4
TDGHCAERDSLLSTS

PIK3R5

336

Q8WYR1
LFAGTEHCTSLIDST

RYR3

2431

Q15413
GATTAHLEDSSACSS

PLEKHG4B

691

Q96PX9
SECGKSFSHSSSLIT

ZNF256

326

Q9Y2P7
CTASEETDHSDLLGT

VIRMA

781

Q69YN4
STTCVHGASFSDSED

MST1R

1031

Q04912
LSKDDSCDFTSHGTL

TTF2

631

Q9UNY4
DSCSFDLEVHESTGT

MYBPC1

151

Q00872
TCSLHIESTTSDDDG

MYPN

1001

Q86TC9