Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C RGS12 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.54e-07	279	105	11	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 PSD TBC1D3H TBC1D3L TBC1D3D TBC1D3C RGS12 TNK2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F SOS2	4.29e-07	507	105	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 PSD TBC1D3H TBC1D3L TBC1D3D TBC1D3C RGS12 TNK2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F SOS2	4.29e-07	507	105	14	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	NRG1 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C RGS12 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.72e-04	656	105	12	GO:0008047
GeneOntologyMolecularFunction	protein serine kinase activity	SPEG PAK4 CLK3 ALPK3 MAST1 TNK2 DCLK2 BRSK1	6.65e-04	363	105	8	GO:0106310
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TSC1 TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.34e-11	109	109	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TSC1 TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	7.01e-08	244	109	11	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	PLXNA3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TSC1 TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.12e-07	335	109	12	GO:0043087
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	BICD2 SLAIN2 PARD6G CLASP2 LRRC43 KIAA1614 EML3 GAS2L1 PARD6A NAV3 UHRF1 MAP7D2 DCLK2 MTCL1 BRSK1	5.82e-06	720	109	15	GO:0000226
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TSC1 TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.75e-05	499	109	11	GO:0051345
GeneOntologyCellularComponent	microtubule end	SLAIN2 CLASP2 GAS2L1 NAV3	4.34e-05	38	108	4	GO:1990752
GeneOntologyCellularComponent	growth cone	DPYSL3 TSC1 CLASP2 GPRIN1 PARD6A TNK2 SMO	2.85e-04	245	108	7	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	DPYSL3 TSC1 CLASP2 GPRIN1 PARD6A TNK2 SMO	3.46e-04	253	108	7	GO:0030427
GeneOntologyCellularComponent	PAR polarity complex	PARD6G PARD6A	3.91e-04	6	108	2	GO:0120157
GeneOntologyCellularComponent	microtubule plus-end	SLAIN2 CLASP2 GAS2L1	4.00e-04	28	108	3	GO:0035371
GeneOntologyCellularComponent	distal axon	DPYSL3 TSC1 CLASP2 GPRIN1 ADRA2C PARD6A TNK2 SMO BRSK1	4.28e-04	435	108	9	GO:0150034
GeneOntologyCellularComponent	axon	NRG1 DPYSL3 TSC1 CLASP2 BCAR1 GPRIN1 ADRA2C PARD6A SCN10A MAST1 TNK2 SMO BRSK1	6.85e-04	891	108	13	GO:0030424
GeneOntologyCellularComponent	cell leading edge	DPYSL3 PSD TSC1 CLASP2 BCAR1 PDLIM4 RAB34 PTPRM PARD6A	1.15e-03	500	108	9	GO:0031252
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	7.35e-12	49	106	9	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.56e-11	53	106	9	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.21e-11	55	106	9	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.21e-11	55	106	9	IPR000195
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TMEM132E-DT TBC1D3I TBC1D3G TBC1D3K	1.70e-09	99	72	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.71e-25	11	112	10	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D RAB34 TBC1D3G TBC1D3F	4.47e-09	74	112	7	16625196
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BICD2 SYNE1 SPEG TSC1 CAMTA2 MED13L FHIP1B NAV3 MAST1 MTCL1 SRRM2	8.98e-08	407	112	11	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PLXNA3 CRYBG2 SPEG MEX3D RNF40 CLASP2 MED13L FHIP1B ADGRA2 EML3 PLEKHH3 GAS2L1 HEG1 ZNF276 KCNH2 ZNF516 TNK2	9.54e-08	1105	112	17	35748872
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	1.30e-07	4	112	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	1.30e-07	4	112	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	3.24e-07	5	112	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	3.24e-07	5	112	3	8471161
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SLAIN2 DPYSL3 PAK4 FAM117B CLASP2 GIGYF1 BCAR1 RGS12 CLK3 OSBPL10 DCLK2 MTCL1 SRRM2	4.27e-06	861	112	13	36931259
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NRG1 DCHS2 SPEG MATN3 TSC1 CLASP2 GPRIN1 RGS12 KRBA1 IGLL1	5.00e-06	497	112	10	36774506
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLAIN2 PAK4 KIAA1549 RNF40 ADGRA2 KIAA1614 ZNF512B MDC1 ZNF516 ANKIB1	8.62e-06	529	112	10	14621295
Pubmed	Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.	NRG1 SCN10A	1.03e-05	2	112	2	19535578
Pubmed	Mouse schwann cells need both NRG1 and cyclic AMP to myelinate.	NRG1 EGR2	1.03e-05	2	112	2	21322058
Pubmed	Association between anorexia nervosa and the hsKCa3 gene: a family-based and case control study.	KCNK3 KCNN3	1.03e-05	2	112	2	11803450
Pubmed	Cloning and tissue expression of the mouse ortholog of AIM1, a betagamma-crystallin superfamily member.	CRYBG2 EGR2	3.08e-05	3	112	2	9716656
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	3.08e-05	3	112	2	21030649
Pubmed	The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.	BCAR1 LOX	3.08e-05	3	112	2	19029090
Pubmed	Tuberous sclerosis complex proteins control axon formation.	TSC1 BRSK1	6.14e-05	4	112	2	18794346
Pubmed	SOGA1 and SOGA2/MTCL1 are CLASP-interacting proteins required for faithful chromosome segregation in human cells.	CLASP2 MTCL1	6.14e-05	4	112	2	33587225
Pubmed	Genetic variation in SCN10A influences cardiac conduction.	KCNH2 SCN10A	6.14e-05	4	112	2	20062061
Pubmed	Nephrocystin-1 interacts directly with Ack1 and is expressed in human collecting duct.	BCAR1 TNK2	6.14e-05	4	112	2	18477472
Pubmed	Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.	RNF40 EGR2	6.14e-05	4	112	2	32672815
Pubmed	Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5.	ADRA2C KCNK3	6.14e-05	4	112	2	9806851
Pubmed	Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination.	NRG1 EGR2	6.14e-05	4	112	2	21057508
Pubmed	Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex.	BCAR1 LOX	6.14e-05	4	112	2	16440329
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BICD2 DCHS2 CRIM1 SYNE1 UBQLN4 RNF40 MED13L ZNF512B USP2 NAV3 MAST1 DCLK2 PRRC2A SOS2	6.77e-05	1285	112	14	35914814
Pubmed	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.	BCAR1 TNK2	1.02e-04	5	112	2	10587647
Pubmed	Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.	LOX ADAMTSL4	1.02e-04	5	112	2	29758265
Pubmed	Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas.	BCAR1 TNK2	1.02e-04	5	112	2	17038317
Pubmed	Neuronal LXR Regulates Neuregulin 1 Expression and Sciatic Nerve-Associated Cell Signaling in Western Diet-fed Rodents.	NRG1 SCN10A	1.02e-04	5	112	2	32286429
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SPEG CLASP2 GPRIN1 PDLIM4 SRRM2 PRRC2A	1.07e-04	231	112	6	16452087
Pubmed	The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.	UBQLN4 USP2	1.53e-04	6	112	2	17290220
Pubmed	No association between EGR gene family polymorphisms and schizophrenia in the Chinese population.	EGR2 KCNH2	1.53e-04	6	112	2	20144677
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	PAK4 TSC1 EML3 RGS12 CLK3 SRRM2	1.83e-04	255	112	6	15324660
Pubmed	A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.	PAK4 TSC1 CLASP2 BCAR1	1.85e-04	87	112	4	17979178
Pubmed	A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.	PARD6G PARD6A	2.14e-04	7	112	2	12629547
Pubmed	PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions.	PARD6G PARD6A	2.14e-04	7	112	2	12459187
Pubmed	Multiple essential functions of neuregulin in development.	NRG1 EGR2	2.14e-04	7	112	2	7477375
Pubmed	A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.	GIGYF1 USP2	2.14e-04	7	112	2	22751931
Pubmed	The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.	PARD6G PARD6A	2.14e-04	7	112	2	23439680
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BICD2 MCM3 GIGYF1 BCAR1 UHRF1 MTCL1 SRRM2 PRRC2A	2.31e-04	503	112	8	16964243
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	FLG CLASP2 UHRF1	2.53e-04	38	112	3	23537643
Pubmed	Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells.	PARD6G PARD6A	2.84e-04	8	112	2	12203721
Pubmed	A phenotype-based screen for embryonic lethal mutations in the mouse.	EGR2 SMO	2.84e-04	8	112	2	9636176
Pubmed	Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse.	NRG1 EGR2	2.84e-04	8	112	2	10662633
Pubmed	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.	PARD6G PARD6A	2.84e-04	8	112	2	11260256
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	SLAIN2 MCM3 CAMTA2 MTCL1	2.92e-04	98	112	4	34943047
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	BICD2 UBQLN4 MCM3 ZNF318 MDC1 SRRM2 PRRC2A	3.20e-04	399	112	7	35987950
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	SLAIN2 CRIM1 ZNF318 GIGYF1 KRBA1	3.33e-04	184	112	5	32908313
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	PAK4 FAM117B BCAR1 SRRM2	3.40e-04	102	112	4	15778465
Pubmed	Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.	PARD6G PARD6A	3.65e-04	9	112	2	18562307
Pubmed	Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.	PARD6G PARD6A	3.65e-04	9	112	2	11257119
Pubmed	Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling.	NRG1 EGR2	3.65e-04	9	112	2	20220021
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	MDC1 SRRM2 PRRC2A	3.65e-04	43	112	3	34672947
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FLG NRG1 COL12A1 ZNF318 GIGYF1 PLEKHH3 CLK3 ZNF516 MTCL1	4.00e-04	689	112	9	36543142
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SLAIN2 GAS2L1 SRRM2 PRRC2A	4.22e-04	108	112	4	19531213
Pubmed	Requirement for downregulation of kreisler during late patterning of the hindbrain.	NRG1 EGR2	4.55e-04	10	112	2	11880356
Pubmed	Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth.	NRG1 HEG1	4.55e-04	10	112	2	22898778
Pubmed	Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.	MCM3 FAM117B	4.55e-04	10	112	2	23382044
Pubmed	The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.	PARD6G PARD6A	4.55e-04	10	112	2	10934474
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	TMPRSS13 SYNE1 RNF40 CLK3 SRRM2	4.55e-04	197	112	5	20811636
Pubmed	Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.	NRG1 EGR2	5.55e-04	11	112	2	23792428
Pubmed	Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation.	MAST1 SMO	5.55e-04	11	112	2	20654717
Pubmed	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	ADGRA2 BRSK1	5.55e-04	11	112	2	19448619
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DPYSL3 PAK4 KIAA1549 TSC1 CLASP2 BCAR1 GPRIN1 ZNF512B PTPRM SRRM2 PRRC2A	5.85e-04	1049	112	11	27880917
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	RBMXL1 SYNE1 FHIP1B ZNF516 UHRF1 PRRC2A	6.22e-04	321	112	6	32098917
Pubmed	A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool.	NRG1 EGR2	6.64e-04	12	112	2	10704452
Pubmed	A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells.	PARD6G PARD6A	7.83e-04	13	112	2	17057644
Pubmed	EGR1 and EGR2 involvement in vertebrate tendon differentiation.	COL12A1 EGR2	7.83e-04	13	112	2	21173153
Pubmed	The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination.	NRG1 EGR2	7.83e-04	13	112	2	21880919
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	BICD2 SYNE1 MUC19 TSC1 GPRIN1 HEG1	8.26e-04	339	112	6	37232246
Pubmed	MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.	PAK4 CLASP2 MAP7D2	8.38e-04	57	112	3	29089450
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	TSC1 GIGYF1 DCLK2 BRSK1	8.97e-04	132	112	4	16944949
Pubmed	Several common variants modulate heart rate, PR interval and QRS duration.	KCNH2 SCN10A	9.12e-04	14	112	2	20062063
Pubmed	Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.	CYP11A1 SMO	9.12e-04	14	112	2	19955443
Pubmed	Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation.	NRG1 EGR2	9.12e-04	14	112	2	19179536
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BICD2 MCM3 ZNF318 GPRIN1 MDC1 ZNF516 SRRM2 MN1 PRRC2A	9.15e-04	774	112	9	15302935
Pubmed	A human MAP kinase interactome.	SYNE1 PAK4 LENG8 NAV3 TNK2 TBC1D3F SOS2	1.02e-03	486	112	7	20936779
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNH2 SCN10A KCNK3 KCNN3	1.09e-03	139	112	4	16985003
Pubmed	EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.	SLAIN2 CLASP2 GAS2L1	1.12e-03	63	112	3	29162697
Pubmed	rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.	SLAIN2 PARD6G CLASP2 EXOSC5	1.18e-03	142	112	4	30217970
Pubmed	Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation.	MCM3 UHRF1	1.20e-03	16	112	2	28803780
Pubmed	Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.	COL12A1 LOX	1.20e-03	16	112	2	24804215
Pubmed	The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.	BICD2 PARD6G MCM3 LENG8 CLK3	1.21e-03	245	112	5	19521500
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	DPYSL3 PAK4 CLASP2 PARD6A SRRM2	1.23e-03	246	112	5	15345747
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBMXL1 LENG8 CLK3 UHRF1 SPTY2D1	1.35e-03	251	112	5	31076518
Pubmed	Genome-wide association analysis of age-at-onset in Alzheimer's disease.	DCHS2 ALPK3	1.35e-03	17	112	2	22005931
Pubmed	LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.	MDC1 PRRC2A	1.35e-03	17	112	2	37072811
Pubmed	Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.	PARD6G PARD6A MTCL1	1.40e-03	68	112	3	14676191
Pubmed	G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.	ADRA2C SOS2	1.52e-03	18	112	2	14712229
Pubmed	Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.	NRG1 EGR2	1.70e-03	19	112	2	28981898
Pubmed	p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.	BICD2 BCAR1	1.70e-03	19	112	2	16105984
Pubmed	Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.	NRG1 CYP11A1	1.70e-03	19	112	2	25855264
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	BICD2 SLAIN2 DPYSL3 MCM3 TSC1 FHIP1B RGS12 LENG8 MAP7D2	1.79e-03	853	112	9	28718761
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	RNF40 MED13L ZNF512B LENG8 MDC1	1.80e-03	268	112	5	33640491
Pubmed	Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.	NRG1 PARD6G	1.88e-03	20	112	2	26876178
Pubmed	PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.	BICD2 BCAR1	1.88e-03	20	112	2	32079660
Pubmed	Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system.	NRG1 EGR2	1.88e-03	20	112	2	21068328
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SLAIN2 PAK4 FAM117B EXOSC5 MED13L CLK3 ZNF516 SRRM2	1.88e-03	695	112	8	23602568
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	CYP11A1 FHIP1B OSBPL10 SRRM2	1.95e-03	163	112	4	24316575
Interaction	YWHAH interactions	SLAIN2 DPYSL3 SPEG MEX3D PAK4 PARD6G TSC1 FAM117B CLASP2 GIGYF1 BCAR1 EML3 RGS12 PARD6A KCNH2 CLK3 KCNK3 OSBPL10 MAST1 DCLK2 MTCL1 SRRM2	7.44e-08	1102	108	22	int:YWHAH
Interaction	PNMA2 interactions	PAK4 PARD6G FAM117B CLASP2 EML3 KRBA1 MAST1 MAP7D2 MTCL1 BRSK1 PRRC2A	1.07e-07	251	108	11	int:PNMA2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TMEM132E-DT TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.15e-13	149	112	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TMEM132E-DT TBC1D3F	4.71e-06	99	112	5	17q12
GeneFamily	PDZ domain containing	PARD6G RGS12 PDLIM4 PARD6A MAST1	1.48e-04	152	60	5	1220
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PLXNA3 DPYSL3 TBC1D3 PSD CRIM1 SPEG MUC19 KIAA1549 FAM117B ZNF318 GIGYF1 MED13L NAV3 ANKIB1 KCNN3 MAST1 MAP7D2 TNK2 DCLK2 IRX2	2.73e-08	1106	109	20	M39071
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_ADVENTITIAL_FIBROBLAST	DPYSL3 COL12A1 LOX NAV3 ADAMTSL4	1.19e-05	71	109	5	M45664
Coexpression	GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	SUSD3 PARD6G ADRA2C PARD6A MAST1 TNK2 DCLK2	1.36e-05	187	109	7	M7123
Coexpression	GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP	BICD2 MEIKIN WDFY4 GIPR NAV3 OSBPL10 MN1	2.03e-05	199	109	7	M8107
Coexpression	LIM_MAMMARY_STEM_CELL_UP	NRG1 DPYSL3 COL12A1 PARD6G BCAR1 ADGRA2 PDLIM4 HEG1 RAB34 EGR2	3.21e-05	479	109	10	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	NRG1 DPYSL3 COL12A1 PARD6G BCAR1 ADGRA2 PDLIM4 HEG1 RAB34 EGR2	3.44e-05	483	109	10	MM1082
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FLG ZNF318 MED13L HEG1 MDC1 NAV3 MTCL1 MN1	3.75e-05	300	109	8	M8702
Coexpression	KAMIKUBO_MYELOID_MN1_NETWORK	RGS12 GAS2L1 MN1	6.46e-05	19	109	3	MM884
Coexpression	KAMIKUBO_MYELOID_MN1_NETWORK	RGS12 GAS2L1 MN1	6.46e-05	19	109	3	M2093
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL	NRG1 DPYSL3 COL12A1 PSD GIPR PARD6A KCNH2 KCNN3 MAST1	7.80e-05	429	109	9	M45694
Coexpression	HAY_BONE_MARROW_STROMAL	DPYSL3 COL12A1 CRIM1 CYP11A1 MATN3 PCDHB5 BCAR1 PDLIM4 PTPRM LOX NAV3 IRX2	8.47e-05	767	109	12	M39209
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3G TBC1D3K TBC1D3F	2.03e-08	90	109	8	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	PLXNA3 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MATN3 MED13L FHIP1B MIR1915HG TBC1D3C GAS2L1 USP2 HEG1 ADRA2C PTPRM ZNF516 ALPK3 BRSK1 TBC1D3G TBC1D3K TBC1D3F	3.53e-07	1153	109	21	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C ADRA2C TBC1D3G TBC1D3K TBC1D3F	1.56e-06	213	109	9	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C ADRA2C TBC1D3G TBC1D3K TBC1D3F	1.56e-06	213	109	9	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L CRIM1 TBC1D3D TBC1D3C LENG8 TBC1D3G TBC1D3K TBC1D3F	1.89e-06	281	109	10	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L CRIM1 TBC1D3D TBC1D3C LENG8 TBC1D3G TBC1D3K TBC1D3F	1.89e-06	281	109	10	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C ADRA2C TBC1D3G TBC1D3K TBC1D3F	4.43e-06	242	109	9	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C USP2 ADRA2C TBC1D3G TBC1D3K TBC1D3F	5.99e-06	320	109	10	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	PLXNA3 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MED13L TBC1D3C RGS12 PLEKHH3 PDLIM4 LENG8 CDAN1 PTPRM CLK3 ZNF516 BRSK1 TBC1D3G TBC1D3K TBC1D3F	1.58e-04	1466	109	19	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 ADRA2C PTPRM LOX KCNK3 BRSK1 MN1	4.98e-07	188	112	7	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLG DCHS2 DPYSL3 COL12A1 CRIM1 SYNE1 LOX	6.58e-07	196	112	7	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 SPEG USP2 KCNK3 ALPK3 DCLK2 MN1	6.81e-07	197	112	7	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DCHS2 DPYSL3 COL12A1 LOX NAV3 MN1 ADAMTSL4	7.29e-07	199	112	7	8de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell	AT1_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 COL12A1 MATN3 WNT9A HEG1	3.24e-06	90	112	5	6cbf30dd3992d8ccfaa74ad9781b9f8735f1ef69
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF40 TCF23 KCNK3 MN1 ADAMTSL4 MOBP	4.42e-06	169	112	6	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF40 TCF23 KCNK3 MN1 ADAMTSL4 MOBP	4.42e-06	169	112	6	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF40 TCF23 KCNK3 MN1 ADAMTSL4 MOBP	4.42e-06	169	112	6	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMPRSS13 MUC19 ADGRA2 KCNH2 NAV3 DCLK2	4.58e-06	170	112	6	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MED13L CDAN1 KRBA1 LOX KCNK3 UHRF1	4.89e-06	172	112	6	da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLASP2 ADRA2C PARD6A KCNH2 MAP7D2 SLC49A3	5.40e-06	175	112	6	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	AT1_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 CRYBG2 COL12A1 TMPRSS13 MATN3 WNT9A	5.58e-06	176	112	6	4a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G FAM117B TCF23 PTPRM TNK2 MN1	5.58e-06	176	112	6	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G FAM117B TCF23 PTPRM TNK2 MN1	5.58e-06	176	112	6	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	Endothelial-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	DPYSL3 PARD6G ADGRA2 USP2 LOX UHRF1	6.56e-06	181	112	6	4fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 DPYSL3 CRIM1 SYNE1 NAV3 OSBPL10	6.56e-06	181	112	6	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 DPYSL3 CRIM1 SYNE1 NAV3 OSBPL10	6.56e-06	181	112	6	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRG1 SPEG WNT9A PDLIM4 DCLK2 MTCL1	7.43e-06	185	112	6	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRIM1 PARD6G BCAR1 LOX NAV3 KCNN3	7.66e-06	186	112	6	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 MATN3 KIAA1549 ADGRA2 KCNK3	7.90e-06	187	112	6	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 MATN3 KIAA1549 ADGRA2 KCNK3	7.90e-06	187	112	6	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 MATN3 KIAA1549 ADGRA2 KCNK3	8.14e-06	188	112	6	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSD PDLIM4 KCNH2 KCNK3 SMO MTCL1	8.39e-06	189	112	6	63449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL12A1 SPEG PDLIM4 KCNH2 KCNK3 MTCL1	8.65e-06	190	112	6	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DCHS2 COL12A1 LOX NAV3 MN1 ADAMTSL4	8.65e-06	190	112	6	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DPYSL3 COL12A1 LOX NAV3 MN1 ADAMTSL4	9.46e-06	193	112	6	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PCDHB5 MIR1915HG HEG1 PTPRM EGR2 MN1	9.46e-06	193	112	6	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 COL12A1 MATN3 WNT9A HEG1 IRX2	1.00e-05	195	112	6	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 COL12A1 PAK4 KIAA1549 PARD6G RGS12	1.00e-05	195	112	6	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DPYSL3 COL12A1 LOX NAV3 MN1 ADAMTSL4	1.03e-05	196	112	6	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 SPEG USP2 KCNK3 ALPK3 DCLK2	1.09e-05	198	112	6	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 SPEG USP2 KCNK3 ALPK3 DCLK2	1.09e-05	198	112	6	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLG DCHS2 DPYSL3 COL12A1 CRIM1 SYNE1	1.13e-05	199	112	6	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLG DCHS2 DPYSL3 COL12A1 CRIM1 SYNE1	1.13e-05	199	112	6	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	wk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DPYSL3 COL12A1 LOX NAV3 MN1 ADAMTSL4	1.13e-05	199	112	6	ab0589c068c24aa989bdca083504fbad0c15221d
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SYNE1 PDLIM4 RAB34 KCNH2 SMO MTCL1	1.16e-05	200	112	6	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	metastatic_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	PSD TBC1D3D GIPR KCNH2 IRX2	3.19e-05	144	112	5	6f1158c85e1d50ef6f2c67abdb2dc855a9786b9a
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	COL12A1 CYP11A1 MATN3 HEG1 IGLL1	5.27e-05	160	112	5	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	WDFY4 ALPK3 SLC49A3 MTCL1 BRSK1	5.59e-05	162	112	5	7d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDAN1 KRBA1 LOX KCNK3 UHRF1	5.76e-05	163	112	5	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 HEG1 PTPRM KCNN3 MN1	6.10e-05	165	112	5	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 KIAA1549 ZNF318 ADGRA2	6.10e-05	165	112	5	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 KIAA1549 ZNF318 ADGRA2	6.10e-05	165	112	5	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SYNE1 KIAA1549 ZNF318 ADGRA2	6.10e-05	165	112	5	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 HEG1 KCNN3 MN1 MOBP	6.28e-05	166	112	5	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	NRG1 ADGRA2 NAV3 UHRF1 PANO1	6.46e-05	167	112	5	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	DPYSL3 SPEG SMO DCLK2 BRSK1	6.46e-05	167	112	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 SPEG HEG1 PTPRM KCNN3	6.83e-05	169	112	5	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	3'_v3-blood-Hematopoietic_progenitors-HSC-MPP\|blood / Manually curated celltypes from each tissue	CYP11A1 PCDHB5 MIR1915HG ADRA2C IGLL1	7.03e-05	170	112	5	1443d7fccc81088dd42dcbb9361e269872542274
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	CRIM1 SPEG ADGRA2 KCNH2 DCLK2	7.43e-05	172	112	5	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MCM3 EXOSC5 RAB34 UHRF1 DCLK2	7.63e-05	173	112	5	a55f310c533432e9e26e400026a5b47245152976
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 COL12A1 MATN3 HEG1 IRX2	7.63e-05	173	112	5	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MCM3 EXOSC5 RAB34 UHRF1 DCLK2	7.63e-05	173	112	5	9c7386bf0a899882c733f0b4921a96afde032a7d
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	MATN3 PARD6G HEG1 SMO MTCL1	7.84e-05	174	112	5	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	NRG1 DPYSL3 PSD GPRIN1 KCNH2	8.06e-05	175	112	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 PSD CLASP2 HEG1 MN1	8.06e-05	175	112	5	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 RGS12 HEG1 ADRA2C MN1	8.06e-05	175	112	5	0c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	NRG1 DPYSL3 PSD GPRIN1 KCNH2	8.06e-05	175	112	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRIM1 MATN3 ADGRA2 PLEKHH3 KCNK3	8.50e-05	177	112	5	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DCHS2 DPYSL3 COL12A1 SYNE1 OSBPL10	8.96e-05	179	112	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 PCDHB5 PTPRM LOX SMO	9.20e-05	180	112	5	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 PCDHB5 PTPRM LOX SMO	9.20e-05	180	112	5	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 PCDHB5 PTPRM LOX SMO	9.20e-05	180	112	5	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 MEX3D PDLIM4 EGR2 MAST1	9.44e-05	181	112	5	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	CYP11A1 KIAA1549 KCNH2 MTCL1 MOBP	9.44e-05	181	112	5	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARD6G BCAR1 LOX NAV3 KCNN3	9.44e-05	181	112	5	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 MEX3D PDLIM4 EGR2 MAST1	9.44e-05	181	112	5	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 RGS12 HEG1 PTPRM MN1	9.44e-05	181	112	5	2f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 RGS12 ADRA2C KCNK3 IRX2	9.69e-05	182	112	5	86a2330ada7637144a67afbf9f3a902901ab1130
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 TCF23 HEG1 ADRA2C PTPRM	9.94e-05	183	112	5	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPYSL3 COL12A1 ADRA2C LOX SMO	9.94e-05	183	112	5	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF23 ADRA2C LOX SMO MN1	9.94e-05	183	112	5	351d575339038bd4a66f408da518c567444208e8
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF23 ADRA2C PTPRM MAP7D2 MN1	1.05e-04	185	112	5	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	MEIKIN MUC19 RGS12 ADRA2C RAB34	1.10e-04	187	112	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	DPYSL3 COL12A1 CRIM1 SPEG DCLK2	1.10e-04	187	112	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN3 GPRIN1 KCNK3 MAST1 IRX2	1.10e-04	187	112	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	DPYSL3 COL12A1 MATN3 HEG1 LOX	1.10e-04	187	112	5	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NRG1 COL12A1 SPEG PDLIM4 MTCL1	1.13e-04	188	112	5	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL3 CLASP2 GPRIN1 PDLIM4 MAST1	1.13e-04	188	112	5	9fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL12A1 SPEG PDLIM4 KCNH2 MTCL1	1.13e-04	188	112	5	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL3 CLASP2 GPRIN1 PDLIM4 MAST1	1.13e-04	188	112	5	459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell	droplet-Kidney-nan-3m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG PLEKHH3 LOX KCNK3 MAP7D2	1.16e-04	189	112	5	a959c9d6a0866582688a4204d625c1e5a123e93d
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSD PDLIM4 KCNH2 SMO MTCL1	1.16e-04	189	112	5	f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 HEG1 PTPRM KCNN3 MN1	1.16e-04	189	112	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPYSL3 MEX3D KIAA1549 KCNH2 MAST1	1.16e-04	189	112	5	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL12A1 SPEG PDLIM4 KCNH2 MTCL1	1.16e-04	189	112	5	da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 DPYSL3 EGR2 LOX ADAMTSL4	1.16e-04	189	112	5	562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 DPYSL3 EGR2 LOX ADAMTSL4	1.16e-04	189	112	5	270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	PARD6G BCAR1 PDLIM4 LOX KCNN3	1.19e-04	190	112	5	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 COL12A1 KIAA1549 PARD6G RGS12	1.22e-04	191	112	5	df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell	LAM-Epithelial-AT1\|Epithelial / Condition, Lineage and Cell class	NRG1 COL12A1 MATN3 HEG1 IRX2	1.22e-04	191	112	5	3457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G PDLIM4 GIPR NAV3 KCNN3	1.22e-04	191	112	5	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G PDLIM4 GIPR NAV3 KCNN3	1.22e-04	191	112	5	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPYSL3 COL12A1 LOX NAV3 MN1	1.25e-04	192	112	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 COL12A1 KIAA1549 PARD6G RGS12	1.25e-04	192	112	5	35f7926628a967f85b26371e795a1b93c6f103ab
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 MATN3 WNT9A HEG1 IRX2	1.25e-04	192	112	5	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	DPYSL3 COL12A1 LOX NAV3 MN1	1.25e-04	192	112	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPYSL3 SPEG PDLIM4 LOX KCNK3	1.28e-04	193	112	5	9a2c1711dec9dd8c8313bcf25bb888ac8e86c3f3
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPYSL3 SPEG PDLIM4 LOX KCNK3	1.28e-04	193	112	5	7c7aa5e2124830d0fa1df11b6413ec6cf780aad0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 HEG1 PTPRM KCNN3 MN1	1.28e-04	193	112	5	0b328f725f6feba263783eaca60c142e80df90f3
Disease	glomerulonephritis	OSBPL10 PRRC2A	3.34e-05	3	99	2	MONDO_0002462
Disease	cortical surface area measurement	BICD2 DCHS2 DPYSL3 FAM117B MED13L MIR1915HG ADGRA2 KIAA1614 MDC1 NAV3 UHRF1 MTCL1 PRRC2A MOBP SOS2	4.15e-05	1345	99	15	EFO_0010736
Disease	Ventricular Fibrillation	KCNH2 SCN10A	3.08e-04	8	99	2	C0042510
Disease	apolipoprotein B measurement	DCHS2 PSD FAM117B GIGYF1 RGS12 GIPR TCF23 KCNK3 SPTY2D1	3.97e-04	663	99	9	EFO_0004615
Disease	Gastric Adenocarcinoma	SPEG TNK2 BRSK1	4.69e-04	45	99	3	C0278701
Disease	Shortened QT interval	KCNH2 SCN10A	6.01e-04	11	99	2	C0151879
Disease	Metastatic melanoma	ALPK3 MAST1 BRSK1	8.03e-04	54	99	3	C0278883
Disease	Agents acting on the renin-angiotensin system use measurement	WNT9A ZNF318 RGS12 KCNK3 UHRF1 SOS2	9.47e-04	335	99	6	EFO_0009931
Disease	T wave morphology measurement	KCNH2 SCN10A	9.88e-04	14	99	2	EFO_0008398
Disease	Romano-Ward Syndrome	KCNH2 SCN10A	1.30e-03	16	99	2	C0035828
Disease	Hydrops Fetalis	BICD2 SOS2	1.84e-03	19	99	2	C0020305
Disease	acetone measurement	GIPR SCART1	1.84e-03	19	99	2	EFO_0010989
Disease	CCL4 measurement	TBC1D3 TBC1D3F	2.04e-03	20	99	2	EFO_0004751
Disease	hyperglycemia (biomarker_via_orthology)	CYP11A1 GIPR	2.24e-03	21	99	2	DOID:4195 (biomarker_via_orthology)
Disease	pulse pressure measurement	SLAIN2 NRG1 CRIM1 ZNF318 BCAR1 MED13L GIPR ZNF516 SCN10A KCNK3 UHRF1 SOS2	2.42e-03	1392	99	12	EFO_0005763
Disease	sciatic neuropathy (implicated_via_orthology)	NRG1 SCN10A	2.69e-03	23	99	2	DOID:11446 (implicated_via_orthology)
Disease	Brugada Syndrome (disorder)	KCNH2 SCN10A	2.93e-03	24	99	2	C1142166
Disease	orofacial cleft, sex interaction measurement	COL12A1 SUSD3 SCN10A	3.06e-03	86	99	3	EFO_0008343, MONDO_0000358

Protein segments in the cluster

Peptide	Gene	Start	Entry
GITPGAQGPSSRGRE	RNF40	591	O75150
TQSRGRGGPLRGPAS	ADAMTSL4	116	Q6UY14
QGGAGRTSPGGRTSP	BICD2	561	Q8TD16
RRTKATAPGPEGGGT	BCAR1	606	P56945
TSVPLGGGAPGTRAS	ADGRA2	386	Q96PE1
GALTASRSPGPGGRL	ADRA2C	331	P18825
SRSPGPGGRLSRASS	ADRA2C	336	P18825
KGGTPAGSARGSPTR	DPYSL3	511	Q14195
QPRGRAARGPGSSGT	ALPK3	571	Q96L96
GSGRRSGPSPTARSG	CLK3	16	P49761
PPTSRGGSSRGGTAI	CAMTA2	311	O94983
PEGGSSSRRPGTSVV	ANKIB1	801	Q9P2G1
GPGEVPTSRGLSSGT	GIPR	436	P48546
GQGQSSGPRTSRPRG	FLG	2226	P20930
RTGSRPSSHGGGGPA	DGAT1	11	O75907
PGAGGRRLRGSGSPS	CDAN1	146	Q8IWY9
PSARVPGTKASRGSG	TNK2	551	Q07912
DGGAPPRSGTTTIRI	PCDHB5	216	Q9Y5E4
SGGSEGPRLPGSSSA	EGR2	286	P11161
GGGATPVSSPSRSLR	MTCL1	1671	Q9Y4B5
HSSPTGGPRGRLNGT	NRG1	381	Q02297
SVARPRPVGGTTGSQ	KIAA1549	1806	Q9HCM3
GSPGASTPVLLTRGG	FHIP1B	896	Q8N612
RSPGSIRRTSPCSGG	MIR1915HG	81	Q5T4H9
AGSSGGSPGEDPRRT	KRBA1	691	A5PL33
PASGTSEPGRARGAG	MATN3	61	O15232
TPRTPRGGGTASGQG	MED13L	1056	Q71F56
SAPVPSGSQSGGRGS	MDC1	981	Q14676
SGSQSGGRGSPVSPR	MDC1	986	Q14676
GAGPPLAGTSRGRGS	GIGYF1	106	O75420
SESPRGTGSGALPSG	NGRN	241	Q9NPE2
GSRPEGTARGTSLPG	MAP7D2	11	Q96T17
SPGGGGRYSDTPSRR	KCNK3	346	O14649
IPGSSGLGSPLGRSR	KIAA1109	4116	Q2LD37
SATRGGGAPSQRGTP	LENG8	371	Q96PV6
SALGPGRAGAGPSSR	KCNH2	906	Q12809
SSGESSGGHRPRRGP	KIAA1614	431	Q5VZ46
PGSRRGAPSSSGGSS	DCLK2	21	Q8N568
SPSRGPASGGTRLTI	PLXNA3	941	P51805
PSSTATSGPGGGSRH	KCNN3	141	Q9UGI6
TSGPGGGSRHRQASP	KCNN3	146	Q9UGI6
TPRVSGETPAVGGGS	MUC19	1756	Q7Z5P9
RTTGPSADGSGTTGP	MUC19	2201	Q7Z5P9
GATGPSVVGSGTTRP	MUC19	2676	Q7Z5P9
PERSGTTGPFTGLTG	MUC19	3021	Q7Z5P9
TTRAGPPGGTTGELS	MUC19	7351	Q7Z5P9
PSKSSTSGIPGRGGH	NAV3	1141	Q8IVL0
GPPAAGARRSSGAGT	MEX3D	496	Q86XN8
SRQGGSGSGPFSPRL	MEIKIN	56	A0A087WXM9
IRAENGTGSSPRGPG	EXOSC5	11	Q9NQT4
TQRGPSGRAPRGGSA	HEG1	91	Q9ULI3
GGRKTPQGSRTSPGA	IRX2	306	Q9BZI1
GRRSSSGEAGTPLVP	MAST1	1421	Q9Y2H9
VVRGGRALGSSGPPS	PARD6G	256	Q9BYG4
PGRRDTPHGRSGSSG	DCHS2	26	Q6V1P9
VRGASGRLTGPPSAG	PARD6A	256	Q9NPB6
TAPRAIPTTGRGSSG	MCM3	361	P25205
RPTRVGLSSLGSGPG	PANO1	101	I0J062
SVSGFSEPVGRRPGG	CEFIP	1246	Q711Q0
QSRALGPGAPGGSSR	IGLL1	46	P15814
GPGAPGGSSRSSLRS	IGLL1	51	P15814
QGESRTGPPGSTGSR	COL12A1	3006	Q99715
GRGSGGSGRSTPQTP	GAS2L1	461	Q99501
GGGGPRTASRSTSPT	FAM117B	81	Q6P1L5
RGTSPTRSAAPGARG	FAM117B	121	Q6P1L5
SRSSRGAGRGHPTPT	TMEM132E-DT	61	A2RUQ5
PTAGGPRSTGLGSTV	CRYBG2	256	Q8N1P7
GSTPRIVSRGDGTPG	CRIM1	306	Q9NZV1
RVPTGEGAGISTRSP	CYP11A1	31	P05108
TDAGGGGSPVPTRRA	BRSK1	406	Q8TDC3
TAGSSGVTAGRPRPT	LOX	106	P28300
STGITGGSHRARPGP	ARRDC1-AS1	26	Q9H2J1
GRSPSDSKTPGRGGA	EML3	486	Q32P44
PVSSGTGAPGSLGRL	GPRIN1	331	Q7Z2K8
GPGTQRPGTGTVSAA	LRRC43	16	Q8N309
GGTGSPGPALRTRTK	PTPRM	361	P28827
PATTARGGPGKAGSR	PAK4	121	O96013
VGGSSAGETRGAPTP	MN1	986	Q10571
GRAGVTTPAPGNRTG	SUSD3	16	Q96L08
TFELRTPSPAGGGRG	PLEKHH3	41	Q7Z736
SSRGAPRGAGPGGSR	RBMXL1	366	Q96E39
PGIRPNTGRHGSTSG	SOS2	1036	Q07890
SGSSPGLRDGSGTPS	SRRM2	1441	Q9UQ35
GSTGSLLRRVAGPGP	PSD	41	A5PKW4
GGGPGSGPRRTSSEE	SLAIN2	76	Q9P270
SSLSEPGPGRSGRGF	SYNE1	8726	Q8NF91
GSPTTSRRPSGTGTG	PDLIM4	111	P50479
SRRPSGTGTGPEDGR	PDLIM4	116	P50479
RGVGGTPRDSAGVSP	PRRC2A	1541	P48634
RSSPLRGPGASRGGS	MOBP	161	Q13875
RGPGASRGGSPVKAS	MOBP	166	Q13875
GSSASRPVPASRGGK	TBC1D3L	366	B9A6J9
SSGGPGRPISGSVSS	SPTY2D1	441	Q68D10
GRPISGSVSSARPLG	SPTY2D1	446	Q68D10
GSVSSARPLGSSRGP	SPTY2D1	451	Q68D10
GPGRSISGSIPAGRT	SPTY2D1	491	Q68D10
GGGSRSSPGSVAASP	OSBPL10	51	Q9BXB5
QPGSRSGSPGRVLTT	CLASP2	456	O75122
GRTTPPGGGSRGCSL	ZNF837	56	Q96EG3
GVSPGPGTRHSAGTR	ZNF837	71	Q96EG3
GAGRAGVLGPSTATP	SLC49A3	476	Q6UXD7
GSSASRPVPASRGGK	TBC1D3H	366	P0C7X1
GGGGFSRSATPTPTV	ZNF516	921	Q92618
ARRLAGPGSTGPGSA	ZFP92	381	A6NM28
PRPSSARGSSGSRGG	TSC1	1021	Q92574
RLGTSSGGDPGGAPR	TMPRSS13	571	Q9BYE2
RSSVPPSKRGTVGAG	RGS12	516	O14924
SGGGTRRLPGSPRQA	SPEG	201	Q15772
GSSASRPVPASRGGK	TBC1D3F	366	A6NER0
TARGSSGGLQAPRGP	SCN10A	966	Q9Y5Y9
SVSGGIGTGATRPFP	WDFY4	1051	Q6ZS81
GVSRTRGRPSLSGGP	ZNF276	26	Q8N554
STPEGARFGRGSGPV	SCART1	276	Q4G0T1
GSSASRPVPASRGGK	TBC1D3E	366	A0A087X179
ATGPGPRSAGGSARR	SMO	36	Q99835
SGSLSPGSRPSGGME	ZNF512B	386	Q96KM6
SAGGGPSRAGSPRRT	UHRF1	651	Q96T88
AISPPRGRASGAGGS	WNT9A	266	O14904
GSSASRPVPASRGGK	TBC1D3D	366	A0A087WVF3
SRATPGPRGTRAGGL	TCF23	56	Q7RTU1
TRGTERPLGSGLSGG	USP2	96	O75604
GSSASRPVPASRGGK	TBC1D3G	366	Q6DHY5
GSSASRPVPASRGGK	TBC1D3	366	Q8IZP1
AGSGSRRSSGGGPSP	UBQLN4	131	Q9NRR5
GGPRSGRSSGSSSGP	ZNF318	21	Q5VUA4
GSSASRPVPASRGGK	TBC1D3K	366	A0A087X1G2
GSSASRPVPASRGGK	TBC1D3I	366	A0A087WXS9
GSSASRPVPASRGGK	TBC1D3C	366	Q6IPX1
SGTRAEGSRPGGAAP	RAB34	151	P0DI83