Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondipeptidase activity

MEP1A SCRN2 SCRN3 SCRN1

1.65e-0718564GO:0016805
GeneOntologyMolecularFunctioncysteine-type exopeptidase activity

SCRN2 SCRN3 SCRN1

2.47e-0610563GO:0070004
GeneOntologyMolecularFunctionphosphothreonine residue binding

FBXW7 NEDD4

2.31e-053562GO:0050816
GeneOntologyMolecularFunctionpeptidase activity

MEP1A CAPN12 HGF SCRN2 SCRN3 ADAM19 PSEN2 C2 SCRN1

7.85e-05654569GO:0008233
GeneOntologyMolecularFunctioncarbohydrate binding

ITLN1 NCAN CHID1 PLOD1 PGD GALNT13

2.26e-04310566GO:0030246
GeneOntologyMolecularFunctionexopeptidase activity

MEP1A SCRN2 SCRN3 SCRN1

2.57e-04110564GO:0008238
MousePhenohemorrhage

HGF ADAM19 PSEN2 COL27A1 RSPO2 MAPK7 PLOD1 IL6ST AURKB FBXW7 NEDD4

5.91e-066644511MP:0001914
MousePhenoabnormal blood circulation

HGF ADAM19 PSEN2 COL27A1 RSPO2 MAPK7 PLOD1 IL6ST AURKB FBXW7 NEDD4

5.61e-058454511MP:0002128
DomainPeptidase_C69

SCRN2 SCRN3 SCRN1

2.70e-083573PF03577
DomainPeptidase_C69

SCRN2 SCRN3 SCRN1

2.70e-083573IPR005322
DomainSushi

NCAN C2 C7

5.36e-0452573PF00084
DomainCCP

NCAN C2 C7

5.99e-0454573SM00032
DomainSUSHI

NCAN C2 C7

6.66e-0456573PS50923
DomainSushi_SCR_CCP_dom

NCAN C2 C7

7.02e-0457573IPR000436
DomainWD40_repeat_dom

ARHGEF10 PAFAH1B1 GNB1 DNAI3 FBXW7

2.09e-03297575IPR017986
DomainG-protein_beta_WD-40_rep

PAFAH1B1 GNB1 FBXW7

2.23e-0385573IPR020472
Domain-

ARHGEF10 PAFAH1B1 GNB1 DNAI3 FBXW7

3.43e-033335752.130.10.10
DomainVWF_A

MDN1 ANAPC1 C2

3.44e-0399573IPR002035
DomainWD40/YVTN_repeat-like_dom

ARHGEF10 PAFAH1B1 GNB1 DNAI3 FBXW7

3.52e-03335575IPR015943
DomainEGF_3

MEP1A ADAM19 NCAN C7

5.73e-03235574PS50026
Pubmed

Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells.

SCRN2 SCRN3 SCRN1

4.17e-09357312221138
Pubmed

The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse.

SCRN2 SCRN3 SCRN1

4.16e-08557333442887
Pubmed

FBXW7 is involved in Aurora B degradation.

AURKB FBXW7

2.64e-06257223095493
Pubmed

ERK5‑regulated RERG expression promotes cancer progression in prostatic carcinoma.

RERG MAPK7

2.64e-06257230431143
Pubmed

Complement components 2 and 7 (C2 and C7) gene polymorphisms are not major risk factors for SLE susceptibility in the Malaysian population.

C2 C7

2.64e-06257221881993
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

CAPN12 SPTBN4 ARHGEF10 SV2B C2 CHID1 GNB1 MAP4K4 PGD SEC14L2

5.62e-061021571026760575
Pubmed

Circulating Levels of Omentin, Leptin, VEGF, and HGF and Their Clinical Relevance with PSA Marker in Prostate Cancer.

HGF ITLN1

7.91e-06357230186533
Pubmed

PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells.

PHLPP1 NEDD4

7.91e-06357234638419
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

SPTBN4 TOM1L1 C2 C7 GNB1 PGD IL6ST SEC14L2 CYFIP2 NEDD4

8.46e-061070571023533145
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SPTBN4 MDN1 ANAPC1 NCAN GNB1 MAP4K4 CYFIP2 STRIP1 NEDD4

2.52e-0596357928671696
Pubmed

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.

PSEN2 FBXW7

2.63e-05557220208556
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SCRN2 ATP6V1H ITLN1 PAFAH1B1 GNB1 PLOD1 PGD CYFIP2 STRIP1

3.82e-05101657919056867
Pubmed

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing.

ANAPC1 MAD2L1BP

5.51e-05757225482201
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

ATP6V1H MDN1 PSEN2 ANAPC1 GNB1 PLOD1 AURKB

5.86e-0560657736538041
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

MDN1 ANAPC1 PHF8 FBXW7

6.13e-0512957423022380
Pubmed

Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage.

ATP6V1H SV2B SORBS3

6.43e-054757331235642
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ANAPC1 PLOD1 MAP4K4 CYFIP2 STRIP1 AURKB

8.98e-0544657624255178
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

FARS2 PAFAH1B1 PLOD1 PGD

1.16e-0415257416009940
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

ADAM19 ITLN1 COL27A1 PLOD1

1.66e-0416757422159717
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MDN1 ANAPC1 NBPF1 PUS7L

1.78e-0417057423314748
Pubmed

The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.

ANAPC1 PHF8

2.03e-041357223979597
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

ADAM19 ARHGEF10 SCRN1 PGD IL6ST

2.36e-0433957537232246
Pubmed

Syntenic assignment of human chromosome 1 homologous loci in the bovine.

GNB1 PGD

2.37e-04145728001974
Pubmed

WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins.

PAFAH1B1 FBXW7

2.37e-041457221070969
Pubmed

FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.

AURKB FBXW7

2.73e-041557231285543
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

ATP6V1H SCRN1 ABCD1 GNB1 PLOD1 PGD NEDD4

3.30e-0480357736517590
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

KLHL34 MAPK7 MAP4K4 AURKB FBXW7

3.62e-0437257522939624
Pubmed

Polymorphisms in innate immunity genes and risk of childhood leukemia.

HGF ADAM19 C2 C7

3.69e-0420657420438785
Pubmed

Risk of meningioma and common variation in genes related to innate immunity.

HGF ADAM19 C2 C7

3.76e-0420757420406964
Pubmed

Common variation in genes related to innate immunity and risk of adult glioma.

HGF ADAM19 C2 C7

3.83e-0420857419423540
Pubmed

Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.

PSEN2 ABCD1

3.97e-04185729090377
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

ANAPC1 HAUS5 MAP4K4 STRIP1

4.12e-0421257433853758
Pubmed

Effect of disease-associated SLC9A9 mutations on protein-protein interaction networks: implications for molecular mechanisms for ADHD and autism.

GNB1 PLOD1

4.92e-042057230927234
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

CHID1 ABCD1 PHF8 GNB1 PLOD1 PGD CYFIP2

4.94e-0485957731536960
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SPTBN4 ATP6V1H SV2B NCAN PAFAH1B1 SCRN1 GNB1 CYFIP2 STRIP1

4.99e-04143157937142655
Pubmed

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.

MDN1 PHF8 MAD2L1BP

5.03e-049457337468549
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ARHGEF10 PHLPP1 SCRN1 PHF8

5.15e-0422557412168954
Pubmed

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.

ATP6V1H SCRN1 PGD

5.52e-049757322360420
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

ANAPC1 PAFAH1B1 HAUS5 GNB1 PLOD1 MAD2L1BP STRIP1 AURKB

5.63e-04115557820360068
Pubmed

Defining the membrane proteome of NK cells.

HGF MDN1 PSEN2 ALG11 CHID1 ABCD1 IL6ST CYFIP2

6.06e-04116857819946888
Pubmed

A visual intracellular classification strategy for uncharacterized human proteins.

SCRN1 MAD2L1BP

7.73e-042557210942595
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

NCAN ABCD1

7.73e-042557235681537
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SPTBN4 NCAN GNB1 CYFIP2

7.75e-0425157427507650
Pubmed

Host determinants of HIV-1 control in African Americans.

SORBS3 C2

8.36e-042657220205591
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

C2 C7 IL6ST CD163

8.46e-0425757416335952
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

GNB1 AURKB FBXW7

9.75e-0411857337105989
Pubmed

Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.

MEP1A RERG FBXW7

1.05e-0312157326354767
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NCAN GNB1 CYFIP2 NEDD4

1.18e-0328157428706196
Pubmed

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.

C2 C7

1.19e-033157219344414
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ATP6V1H PAFAH1B1 SORBS3 SCRN1 CHID1 PLOD1 PGD AURKB

1.19e-03129757833545068
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CAPN12 ADAM19 PAFAH1B1 GALNT13 AURKB NEDD4

1.22e-0373057634857952
Pubmed

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.

PSEN2 C7

1.27e-033257218842294
Pubmed

Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20.

ANAPC1 MAD2L1BP

1.35e-033357232152539
Pubmed

Ubiquitin chain elongation requires E3-dependent tracking of the emerging conjugate.

ANAPC1 MAD2L1BP

1.35e-033357225306918
Pubmed

β-Catenin gain of function in muscles impairs neuromuscular junction formation.

HGF SV2B

1.43e-033457222627288
Pubmed

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

MDN1 DNAI3

1.52e-033557224515614
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

SORBS3 PHLPP1 PHF8 PLOD1 CYFIP2 AURKB FBXW7

1.58e-03104957727880917
Cytoband5q33.3

ADAM19 CYFIP2

9.29e-04365725q33.3
Cytoband1p36.22

PLOD1 PGD

9.81e-04375721p36.22
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

NCAN C2 C7

3.35e-04574331179
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 SPTBN4 ARHGEF10 GNB1 IL6ST

4.82e-061935752483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-T_reticular|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RERG RSPO2 C2 C7 IL6ST

5.46e-061985755c96778cf5623c662c2259fe70f8665c14a161dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MDN1 COL27A1 C7 IL6ST

5.46e-06198575a860246bcea847249a78fd2e86ed8e04371060db
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

PAFAH1B1 SCRN1 GNB1 MAP4K4 CD163

5.73e-06200575c92e4fc0442404481fcac623d691dae6215b852d
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PSEN2 ARHGEF10 SORBS3 PLOD1 NEDD4

5.73e-0620057566f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL27A1 RSPO2 C7 DNAI3

2.00e-05125574b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

HGF SV2B RSPO2 FBXW7

3.78e-051475748f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TRPM7 MAPK7 PUS7L NEDD4

4.41e-05153574553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TRPM7 MAPK7 PUS7L NEDD4

4.41e-0515357488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

RERG ADAM19 CYFIP2 AURKB

5.51e-05162574af9999e5fcd28ff1f401d52fd220315752c40027
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SV2B COL27A1 RSPO2 SEC14L2

6.80e-05171574d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCellfacs-Marrow-KLS-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF10 NCAN C2 CHID1

7.11e-05173574295bfe1efa648173c2d5981025bc61c576baf53f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MDN1 SORBS3 CD163 CYFIP2

7.27e-05174574d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

ARHGEF10 GAL3ST4 C2 PLOD1

7.77e-0517757452c2ba74a8605260a2623e7d151286e504ac4d19
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SV2B COL27A1 NCAN GALNT13

7.77e-051775741dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SV2B COL27A1 NCAN GALNT13

7.77e-05177574426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL27A1 RSPO2 C7 DNAI3

8.29e-0518057408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RERG RSPO2 C7 DNAI3

8.47e-051815749ede19228ba5c0668a9c06c915510b95585216ef
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAM19 XKR6 MAP4K4 CYFIP2

8.47e-051815748d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SCRN2 PSEN2 PHF8 IL6ST

8.84e-05183574fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-05185574ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-051855743beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-05185574ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-051855749aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-0518557442939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ITLN1 GAL3ST4 C2 NBPF1

9.22e-05185574f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITLN1 GAL3ST4 C2 NBPF1

9.22e-051855747a3612520ae4f0cd61480eadba31eecce001419d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN12 COL27A1 PTH2R NEDD4

9.41e-05186574f28d72b47624b69a580b4429e2be560a26898591
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGF RERG COL27A1 C7

9.61e-0518757476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN12 RERG COL27A1 PTH2R

1.00e-041895743b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF RSPO2 C7 DNAI3

1.00e-041895742a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MDN1 C7 IL6ST

1.02e-041905741121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MDN1 C7 IL6ST

1.02e-04190574048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL27A1 RSPO2 C7 DNAI3

1.02e-0419057445df8fee00f8949937863159d7aa042e72748d9b
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HGF GAL3ST4 C2 CD163

1.02e-04190574d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class （2021.01.30）

HGF SV2B ITLN1 GAL3ST4

1.04e-041915743ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RERG COL27A1 C7 DNAI3

1.04e-04191574c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RERG COL27A1 C7 DNAI3

1.04e-04191574cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF RSPO2 C7 DNAI3

1.06e-04192574deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

HGF RERG RSPO2 C7

1.09e-04193574ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

HGF RERG RSPO2 C7

1.11e-0419457429a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

HGF GAL3ST4 C2 CD163

1.13e-0419557410fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGF RERG COL27A1 C7

1.13e-041955743d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HGF GAL3ST4 SCRN1 CD163

1.13e-0419557467b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGF RERG COL27A1 C7

1.13e-0419557444d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HGF GAL3ST4 ABCD1 CD163

1.15e-041965747c8aa5853d7096628e35af665097c0299c329753
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGF GAL3ST4 ABCD1 CD163

1.15e-04196574f60b220ed117bcc33e0f7bbf5b53d3b1422ebaca
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HGF GAL3ST4 ABCD1 CD163

1.15e-04196574bcd274db4955ea76ca26267a272c7d1929db24f4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGF RERG COL27A1 C7

1.15e-04196574ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGF RERG COL27A1 C7

1.15e-0419657430ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGF GAL3ST4 ABCD1 CD163

1.15e-0419657480b9139d91dda4de69830d2d443859e047ab5503
ToppCellMild_COVID-19-Myeloid-MoAM1|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

HGF GAL3ST4 ABCD1 CD163

1.15e-04196574ea3fbe81b4ecb6ccc8031f6d99da93c9f9f8c1aa
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HGF C7 DNAI3 IL6ST

1.17e-04197574fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

RERG RSPO2 C7 IL6ST

1.17e-04197574156155c2f0c1a2461e45803da578af18ee221660
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RERG COL27A1 C2 PLOD1

1.17e-0419757486145bc1e585b4ae136e755cafd6579da2abfa65
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

RERG RSPO2 C7 IL6ST

1.17e-04197574d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF COL27A1 C7 IL6ST

1.17e-041975749b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF RERG RSPO2 C7

1.17e-0419757413896ec65ccda0b928c91d41112dc01b480036b7
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

HGF RERG RSPO2 C7

1.20e-041985742d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HGF RERG RSPO2 C7

1.20e-041985747f728ca6d5317890c6fcde3ce6c10c0970d49a05
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

HGF RERG COL27A1 C7

1.20e-04198574df3de77216f5c5d6141ec44d01c56b942f611838
ToppCelldistal-1-mesenchymal-Alveolar_Fibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HGF RERG RSPO2 C7

1.20e-041985746594c35ab203dc51462167c61807b0d49fa30fb2
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

HGF RERG COL27A1 C7

1.20e-04198574bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HGF C7 DNAI3 IL6ST

1.22e-04199574a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

HGF RERG C7 IL6ST

1.22e-04199574b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellBAL-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

GAL3ST4 C2 PGD CD163

1.22e-04199574d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF RERG RSPO2 C7

1.24e-04200574e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HGF RERG RSPO2 C7

1.24e-042005748c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

HGF RERG RSPO2 C7

1.24e-04200574aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HGF RERG RSPO2 C7

1.24e-04200574a510deaada669e690329183e18df02870bd204b3
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF RERG RSPO2 C7

1.24e-04200574cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

HGF C7 DNAI3 IL6ST

1.24e-04200574a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PSEN2 ARHGEF10 SORBS3 NEDD4

1.24e-04200574432384faeade8e609154fab3d96c955a8ec868dd
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF RERG RSPO2 C7

1.24e-04200574311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF RERG RSPO2 C7

1.24e-0420057434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

HGF RERG RSPO2 C7

1.24e-04200574c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGF RERG RSPO2 C7

1.24e-04200574dd4228cbed8a4395166a6332e08d44d88bebe3b9
DiseaseIGA Glomerulonephritis

C2 CD163 AURKB

3.33e-0534543C0017661
DiseaseT-cell immunoglobulin and mucin domain 1 measurement

ADAM19 CYFIP2

6.86e-057542EFO_0010812
Diseasestabilin-2 measurement

C2 C7

9.14e-058542EFO_0020752
Diseasetransmembrane protein 9 measurement

COL27A1 C2

1.17e-049542EFO_0803190
DiseaseDNA repair protein rad51 homolog 1 measurement

C2 C7

1.47e-0410542EFO_0020330
Diseaseglycerol-3-phosphate dehydrogenase 1-like protein measurement

C2 C7

1.79e-0411542EFO_0801640
Diseasetyrosine-protein phosphatase non-receptor type 1 measurement

C2 C7

2.53e-0413542EFO_0020834
DiseaseSLAM family member 7 measurement

ITLN1 C7

4.39e-0417542EFO_0008287
Diseasealpha-tocopherol measurement

HGF SEC14L2

6.12e-0420542EFO_0007898
Diseasecerebrospinal fluid biomarker measurement

ATP6V1H RSPO2 C7

7.34e-0496543EFO_0006794
Diseaseatrophic macular degeneration

C2 NLRP5

9.60e-0425542EFO_1001492
DiseaseComplement deficiency disease

C2 C7

1.67e-0333542C0272242
Diseasejoint hypermobility measurement

XKR6 NEDD4

1.67e-0333542EFO_0007905

Protein segments in the cluster

PeptideGeneStartEntry
WNEHFGIGVVECMAA

ALG11

396

Q2TAA5
EENHMGWFCVEDDGN

ARHGEF10

856

O15013
ALVGLEVWTHGNMCE

ADAM19

256

Q9H013
CDWVGDEGAGHFVKM

PGD

171

P52209
GCINGQIVMWDITAH

DNAI3

416

Q8IWG1
LWDFQGFECIRTMHG

PAFAH1B1

176

P43034
HHILQREGGWEAMCD

ABCD1

586

P33897
LDQWLQVGGDMCVHA

ANAPC1

1856

Q9H1A4
QAIDLWSVGCIFGEM

MAPK7

241

Q13164
GHDDQLWLVMEFCGA

MAP4K4

96

O95819
HENDMRGKCTVGDRW

ITLN1

86

Q8WWA0
MREARAHFWCGAVGE

KLHL34

411

Q8N239
LECNFGHIVWTEGMR

MDN1

1356

Q9NU22
TVVMAQGHRNCGEDW

MAD2L1BP

211

Q15013
MCGLGDVDVNDWREH

NEDD4

1196

P46934
MWDGETAVCDNGAGH

C2

136

P06681
IEEQWEDFCSMLGTH

NLRP5

766

P59047
GLMDHTESGKICQRW

HGF

221

P14210
EARELGCWAVEEMGV

HAUS5

6

O94927
GVMHVDECVEFHRLW

CYFIP2

1141

Q96F07
DALCWGLDDVVGFMH

GAL3ST4

316

Q96RP7
EQQVCMAVDIGGHRW

NBPF1

861

Q3BBV0
CDELVEEMEHFGQWS

PLOD1

566

Q02809
EMSFRIWQCGGSLEI

GALNT13

321

Q8IUC8
GEGVICLTHRQWMEV

CAPN12

701

Q6ZSI9
KMRCEWDGGRETHLE

IL6ST

141

P40189
WDVREGMCRQTFTGH

GNB1

211

P62873
ARCGEDLRWLVGEMH

C7

611

P10643
WDIETGQCLHVLMGH

FBXW7

486

Q969H0
VSMDGCKVQDGRWHQ

COL27A1

1806

Q8IZC6
GRIWMDHVSCRGNES

CD163

111

Q86VB7
CVLRWQFMSDGADVG

SEC14L2

301

O76054
FEVTGLHDVDQGWMR

CHID1

121

Q9BWS9
FAWVEADGVNCIMGV

ATP6V1H

216

Q9UI12
GVQTEDWGQFMHICD

TOM1L1

26

O75674
ETIMDECGHGRFQWI

SV2B

96

Q7L1I2
HRFGMTEEGCIQAWF

PUS7L

506

Q9H0K6
LWGAEMGANEHGVCI

SCRN2

81

Q96FV2
LWGAEMGANEHGVCI

SCRN3

76

Q0VDG4
GEDCVVMVAHESGRW

NCAN

1181

O14594
ICGMIQGTRDDTDWA

MEP1A

276

Q16819
HQECEGDKAEWRTMR

STRIP1

231

Q5VSL9
EETMECVEGCEVGHW

RSPO2

136

Q6UXX9
LWGAEMGANEHGVCI

SCRN1

76

Q12765
DTIQREGHMRWGEGF

RERG

66

Q96A58
EGRMHNEKVDLWCIG

AURKB

246

Q96GD4
IIHGGTDFCMSKWEE

XKR6

401

Q5GH73
DCIGMIWQNHDIEED

ZNF441

41

Q8N8Z8
LTVWNFGAVGMVCIH

PSEN2

206

P49810
MFGEVHACELWIGEK

SPTBN4

886

Q9H254
GDRVDVMQQCDDGWF

SORBS3

636

O60504
FTGLGWEIRMHCELF

PTH2R

386

P49190
EMIQCVVCEDWFHGR

UBR7

151

Q8N806
WRVQEEGMDSEIGCL

PHLPP1

506

O60346
MCQDWFHGSCVGVEE

PHF8

61

Q9UPP1
FHGEWLEVLGCGVME

FARS2

281

O95363
HSAGQWFAVEECMTG

TRPM7

1711

Q96QT4