Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	PRSS2 CTRB2 PRSS3P2 FAP RHBDD3 CTRB1 KLK1	6.56e-05	190	105	7	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	PRSS2 CTRB2 PRSS3P2 FAP RHBDD3 CTRB1 KLK1	1.12e-04	207	105	7	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	PRSS2 CTRB2 PRSS3P2 FAP RHBDD3 CTRB1 KLK1	1.30e-04	212	105	7	GO:0017171
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPA1 CPB1 FOLH1B	5.71e-04	31	105	3	GO:0004181
GeneOntologyMolecularFunction	nodal binding	CFC1 CFC1B	7.51e-04	8	105	2	GO:0038100
GeneOntologyMolecularFunction	tumor necrosis factor receptor binding	TNFSF14 TRAF4 TRAP1	8.18e-04	35	105	3	GO:0005164
GeneOntologyCellularComponent	cell surface	RPS6KB1 MUC16 ADGRV1 LCT CD163 FAP CSF1R P2RY1 CSPG4 CFC1 PKD1 CNTNAP2 FOLH1B PAM CFC1B FERMT2 AGAP2 TJP3	9.88e-06	1111	105	18	GO:0009986
GeneOntologyCellularComponent	lamellipodium membrane	FAP CSPG4 FERMT2	1.77e-04	22	105	3	GO:0031258
Domain	LamG	LAMA5 COL18A1 CELSR3 CSPG4 CNTNAP2	4.23e-06	44	103	5	SM00282
Domain	Laminin_G	LAMA5 COL18A1 CELSR3 CSPG4 CNTNAP2	1.68e-05	58	103	5	IPR001791
Domain	LAM_G_DOMAIN	LAMA5 CELSR3 CSPG4 CNTNAP2	5.57e-05	38	103	4	PS50025
Domain	Laminin_G_2	LAMA5 CELSR3 CSPG4 CNTNAP2	6.84e-05	40	103	4	PF02210
Domain	CFC	CFC1 CFC1B	9.00e-05	3	103	2	PF09443
Domain	Cryptic/Cripto_CFC-dom	CFC1 CFC1B	9.00e-05	3	103	2	IPR019011
Domain	Galactose-bd-like	DDR1 LAMA5 SSPOP CNTNAP2 HERC2	1.72e-04	94	103	5	IPR008979
Domain	-	LAMA5 ADGRV1 CELSR3 CSPG4 CNTNAP2	1.81e-04	95	103	5	2.60.120.200
Domain	FA58C	DDR1 SSPOP CNTNAP2	2.02e-04	21	103	3	SM00231
Domain	FA58C_3	DDR1 SSPOP CNTNAP2	2.02e-04	21	103	3	PS50022
Domain	FA58C_1	DDR1 SSPOP CNTNAP2	2.02e-04	21	103	3	PS01285
Domain	FA58C_2	DDR1 SSPOP CNTNAP2	2.02e-04	21	103	3	PS01286
Domain	F5_F8_type_C	DDR1 SSPOP CNTNAP2	3.03e-04	24	103	3	PF00754
Domain	FA58C	DDR1 SSPOP CNTNAP2	3.03e-04	24	103	3	IPR000421
Domain	-	DDR1 SSPOP CNTNAP2 HERC2	7.09e-04	73	103	4	2.60.120.260
Domain	-	CPA1 CPB1	8.25e-04	8	103	2	3.30.70.340
Domain	Propep_M14	CPA1 CPB1	8.25e-04	8	103	2	PF02244
Domain	M14A_act_pep	CPA1 CPB1	8.25e-04	8	103	2	IPR003146
Domain	GPS	ADGRV1 CELSR3 PKD1	8.61e-04	34	103	3	SM00303
Domain	GPS	ADGRV1 CELSR3 PKD1	9.38e-04	35	103	3	PF01825
Domain	GPS	ADGRV1 CELSR3 PKD1	1.02e-03	36	103	3	PS50221
Domain	LisH	TBL1Y TBL1XR1	1.06e-03	9	103	2	PF08513
Domain	GPS	ADGRV1 CELSR3 PKD1	1.10e-03	37	103	3	IPR000203
Domain	ConA-like_dom	LAMA5 ADGRV1 COL18A1 CELSR3 CSPG4 CNTNAP2	1.35e-03	219	103	6	IPR013320
Domain	TRYPSIN_SER	PRSS2 CTRB2 CTRB1 KLK1	1.55e-03	90	103	4	IPR033116
Domain	C8	MUC19 SSPOP	1.92e-03	12	103	2	PF08742
Domain	Peptidase_M28	NCLN FOLH1B	1.92e-03	12	103	2	PF04389
Domain	TIL	MUC19 SSPOP	1.92e-03	12	103	2	PF01826
Domain	Peptidase_M28	NCLN FOLH1B	1.92e-03	12	103	2	IPR007484
Domain	Unchr_dom_Cys-rich	MUC19 SSPOP	2.26e-03	13	103	2	IPR014853
Domain	C8	MUC19 SSPOP	2.26e-03	13	103	2	SM00832
Domain	TRYPSIN_HIS	PRSS2 CTRB2 CTRB1 KLK1	2.54e-03	103	103	4	IPR018114
Domain	TIL_dom	MUC19 SSPOP	2.62e-03	14	103	2	IPR002919
Domain	TRYPSIN_SER	PRSS2 CTRB2 CTRB1 KLK1	2.82e-03	106	103	4	PS00135
Domain	EGF_1	LAMA5 SSPOP CELSR3 CFC1 CNTNAP2 CFC1B	2.90e-03	255	103	6	PS00022
Domain	TRYPSIN_HIS	PRSS2 CTRB2 CTRB1 KLK1	2.91e-03	107	103	4	PS00134
Domain	VWF_type-D	MUC19 SSPOP	3.44e-03	16	103	2	IPR001846
Domain	VWFD	MUC19 SSPOP	3.44e-03	16	103	2	PS51233
Domain	VWD	MUC19 SSPOP	3.44e-03	16	103	2	SM00216
Domain	VWD	MUC19 SSPOP	3.44e-03	16	103	2	PF00094
Domain	EGF_2	LAMA5 SSPOP CELSR3 CFC1 CNTNAP2 CFC1B	3.50e-03	265	103	6	PS01186
Domain	Peptidase_S1A	PRSS2 CTRB2 CTRB1 KLK1	3.55e-03	113	103	4	IPR001314
Domain	TRYPSIN_DOM	PRSS2 CTRB2 CTRB1 KLK1	3.78e-03	115	103	4	PS50240
Domain	Propept_inh	CPA1 CPB1	3.88e-03	17	103	2	IPR009020
Domain	Tryp_SPc	PRSS2 CTRB2 CTRB1 KLK1	4.02e-03	117	103	4	SM00020
Domain	CTCK_1	MUC19 SSPOP	4.35e-03	18	103	2	PS01185
Domain	Zn_pept	CPA1 CPB1	4.35e-03	18	103	2	SM00631
Domain	Trypsin_dom	PRSS2 CTRB2 CTRB1 KLK1	4.53e-03	121	103	4	IPR001254
Domain	Trypsin	PRSS2 CTRB2 CTRB1 KLK1	4.53e-03	121	103	4	PF00089
Domain	Peptidase_S1_PA	PRSS2 CTRB2 CTRB1 KLK1	4.80e-03	123	103	4	IPR009003
Domain	VWC_out	MUC19 SSPOP	4.84e-03	19	103	2	SM00215
Domain	CARBOXYPEPT_ZN_2	CPA1 CPB1	4.84e-03	19	103	2	PS00133
Domain	UBA-like	TNRC6B CBL RHBDD3	5.32e-03	64	103	3	IPR009060
Domain	CARBOXYPEPT_ZN_1	CPA1 CPB1	5.36e-03	20	103	2	PS00132
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	PRSS2 CTRB2 COL18A1 CTRB1 KLK1	1.86e-06	38	77	5	MM14611
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	PRSS2 CTRB2 COL18A1 CTRB1	2.99e-05	33	77	4	M26976
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TEAD2 MORN1 SZT2 KHNYN KDM3B LAMA5 NCLN RALGAPA2 TRAF4 AATK SLC2A4RG CELSR3 CSPG4 HPS6 PKD1 OSBPL5 STRN4 HERC2 TJP3	8.23e-10	1105	105	19	35748872
Pubmed	Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.	PRSS2 CTRB2 CTRB1	5.31e-07	6	105	3	23814066
Pubmed	Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983), Seventh International Workshop on Human Gene Mapping.	CTRB2 CPA1 CTRB1 KLK1	4.29e-06	36	105	4	6690234
Pubmed	The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.	CTRB2 CPA1 CPB1 CTRB1	4.29e-06	36	105	4	25063451
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RPS6KB1 KLC2 FCHO1 PITPNM1 TRAF4 TRAP1 SLC2A4RG MVB12A TEX264 PKD1 NUMB FERMT2 SEZ6	4.48e-06	925	105	13	28986522
Pubmed	Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.	PRSS2 CTRB2 LCT CTRB1	7.29e-06	41	105	4	23676500
Pubmed	Inhibition of human pancreatic proteinases by mucus proteinase inhibitor, eglin c and aprotinin.	PRSS2 SLPI	9.03e-06	2	105	2	8573092
Pubmed	Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.	CTRB2 CTRB1	9.03e-06	2	105	2	30076839
Pubmed	The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.	CTRB2 CTRB1	9.03e-06	2	105	2	28951524
Pubmed	Endoplasmic stress-inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: A case-control study and meta-analysis.	CPA1 CPB1	9.03e-06	2	105	2	34817877
Pubmed	Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.	CTRB2 CTRB1	9.03e-06	2	105	2	28754779
Pubmed	Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.	CTRB2 CTRB1	9.03e-06	2	105	2	33036922
Pubmed	Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.	CTRB2 CTRB1	9.03e-06	2	105	2	2565717
Pubmed	c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms.	CBL CSF1R	9.03e-06	2	105	2	11847211
Pubmed	The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.	CFC1 CFC1B	9.03e-06	2	105	2	11174844
Pubmed	Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.	CTRB2 CTRB1	9.03e-06	2	105	2	2917002
Pubmed	Genomic cloning and partial characterization of human chymotrypsinogen gene.	CTRB2 CTRB1	9.03e-06	2	105	2	8186414
Pubmed	Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease.	DDR1 PKD1	9.03e-06	2	105	2	31260458
Pubmed	Transient CSF1R inhibition ameliorates behavioral deficits in Cntnap2 knockout and valproic acid-exposed mouse models of autism.	CSF1R CNTNAP2	9.03e-06	2	105	2	39425203
Pubmed	Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.	CFC1 CFC1B	9.03e-06	2	105	2	11327798
Pubmed	Tumor necrosis factor receptor-associated factor (TRAF) 4 is a new binding partner for the p70S6 serine/threonine kinase.	RPS6KB1 TRAF4	9.03e-06	2	105	2	12801526
Pubmed	Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.	CFC1 CFC1B	9.03e-06	2	105	2	11024280
Pubmed	Association of Cbl with Fms and p85 in response to macrophage colony-stimulating factor.	CBL CSF1R	9.03e-06	2	105	2	10648820
Pubmed	CSF-1R expression in tumor-associated macrophages is associated with worse prognosis in classical Hodgkin lymphoma.	CD163 CSF1R	9.03e-06	2	105	2	24619759
Pubmed	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.	CFC1 CFC1B	9.03e-06	2	105	2	11062482
Pubmed	Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.	CPA1 CPB1	9.03e-06	2	105	2	29669919
Pubmed	Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.	LAMA5 ADGRV1 PLA2G12B HERC2	9.70e-06	44	105	4	27534441
Pubmed	Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.	CFC1 CFC1B	2.70e-05	3	105	2	16835440
Pubmed	C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.	CBL CSF1R	2.70e-05	3	105	2	11850825
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.	CTRB2 CTRB1	2.70e-05	3	105	2	1016231
Pubmed	Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.	CTRB2 CTRB1	2.70e-05	3	105	2	38981616
Pubmed	Further studies on the human pancreatic binary complexes involving procarboxypeptidase A.	CPA1 CPB1	2.70e-05	3	105	2	2307232
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS2 PRSS3P2	2.70e-05	3	105	2	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS2 PRSS3P2	2.70e-05	3	105	2	9732462
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.	CTRB2 CTRB1	2.70e-05	3	105	2	1008801
Pubmed	Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.	CTRB2 CTRB1	2.70e-05	3	105	2	34643096
Pubmed	Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.	CTRB2 CTRB1	2.70e-05	3	105	2	32678161
Pubmed	The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes.	CBL CSF1R	2.70e-05	3	105	2	38170572
Pubmed	Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia.	PTCRA CBL	2.70e-05	3	105	2	19966856
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SZT2 KDM3B LAMA5 ADGRV1 CELSR3 MTUS1 OSBPL5 CNTNAP2 BOP1	3.36e-05	529	105	9	14621295
Pubmed	Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.	CFC1 PKD1 CFC1B	3.42e-05	21	105	3	16291790
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	DDR1 LAMA5 MUC16 COL18A1 TGM3 TM9SF2 SLPI PAM	4.04e-05	417	105	8	19199708
Pubmed	Cystic kidney diseases.	NPHP3 PKD1	5.40e-05	4	105	2	9263671
Pubmed	Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer.	RPS6KB1 TRAF4	5.40e-05	4	105	2	25738361
Pubmed	Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages.	CBL CSF1R	5.40e-05	4	105	2	8947469
Pubmed	The effect of P2Y-mediated platelet activation on the release of VEGF and endostatin from platelets.	COL18A1 P2RY1	5.40e-05	4	105	2	20063989
Pubmed	Cripto in tumors and embryo development.	CFC1 CFC1B	5.40e-05	4	105	2	11825688
Pubmed	Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia.	CBL CSF1R	5.40e-05	4	105	2	14738146
Pubmed	A high-lipid diet potentiates left ventricular dysfunction in nitric oxide synthase 3-deficient mice after chronic pressure overload.	NPHP3 PKD1	5.40e-05	4	105	2	20554900
Pubmed	Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.	CFC1 CFC1B	5.40e-05	4	105	2	9576836
Pubmed	Role of the EGF-CFC gene cripto in cell differentiation and embryo development.	CFC1 CFC1B	5.40e-05	4	105	2	11992720
Pubmed	Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.	NPHP3 PKD1	5.40e-05	4	105	2	20562878
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SAMD4B KHNYN KDM3B GIGYF1 CBL TBL1XR1 MEX3C MVB12A HPS6 NUMB FERMT2 TJP3	7.16e-05	1038	105	12	26673895
Pubmed	Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).	CTRB2 CTRB1	8.97e-05	5	105	2	4461036
Pubmed	Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.	TBL1Y TBL1XR1	8.97e-05	5	105	2	21459324
Pubmed	Animal models of polycystic kidney disease.	NPHP3 PKD1	8.97e-05	5	105	2	7661851
Pubmed	A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.	CFC1 CFC1B	8.97e-05	5	105	2	9053319
Pubmed	Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.	CTRB2 CTRB1	8.97e-05	5	105	2	6589791
Pubmed	Purification and properties of five different forms of human procarboxypeptidases.	CPA1 CPB1	8.97e-05	5	105	2	2920728
Pubmed	Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.	CFC1 CFC1B	8.97e-05	5	105	2	25224222
Pubmed	Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.	CTRB2 CTRB1	8.97e-05	5	105	2	1820020
Pubmed	The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation.	CBL CSF1R	8.97e-05	5	105	2	17353186
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	RPS6KB1 KHNYN TAF6L TRAF4 MVB12A ACTL8 HPS6 RHBDD3 HERC2	9.27e-05	604	105	9	38803224
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	KHNYN KDM3B LAMA5 FCHO1 TRAF4 ACTL8 STRN4 HERC2	1.09e-04	481	105	8	28190767
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ADGRV1 CSF1R CNTNAP2 HERC2	1.26e-04	84	105	4	15203218
Pubmed	Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.	TBL1Y TBL1XR1	1.34e-04	6	105	2	28348241
Pubmed	M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721.	CBL CSF1R	1.34e-04	6	105	2	17420256
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC16	1.34e-04	6	105	2	19110483
Pubmed	microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.	NPHP3 PKD1	1.34e-04	6	105	2	28205547
Pubmed	Genetic differences between five European populations.	LCT HERC2	1.34e-04	6	105	2	20616560
Pubmed	A role of the cryptic gene in the correct establishment of the left-right axis.	CFC1 CFC1B	1.34e-04	6	105	2	10574770
Pubmed	Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease.	CBL PKD1	1.34e-04	6	105	2	20852388
Pubmed	Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.	CFC1 CFC1B	1.34e-04	6	105	2	12052855
Pubmed	CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins.	CBL CSF1R	1.34e-04	6	105	2	10025673
Pubmed	GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.	CFC1 CFC1B	1.34e-04	6	105	2	17991893
Pubmed	Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways.	CBL CSF1R	1.34e-04	6	105	2	7782294
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DDR1 MORN1 RPS6KB1 SAMD4B TNRC6B ADGRV1 TBL1XR1 SSPOP SBK1 COL18A1 OSBPL5 FOLH1B NUMB CREB3L2	1.57e-04	1489	105	14	28611215
Pubmed	Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock.	RPS6KB1 CBL	1.88e-04	7	105	2	20622121
Pubmed	Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.	CFC1 CFC1B	1.88e-04	7	105	2	10521397
Pubmed	Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.	LCT PAM	1.88e-04	7	105	2	8672144
Pubmed	Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.	TBL1Y TBL1XR1	1.88e-04	7	105	2	27646874
Pubmed	Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.	CFC1 CFC1B	1.88e-04	7	105	2	19906859
Pubmed	The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.	TBL1Y TBL1XR1	1.88e-04	7	105	2	15695367
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	TEAD2 RALGAPA2 PKHD1L1 FAP NPHP3 MIA2 PKD1 NUMB PAM	2.40e-04	686	105	9	29987050
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	LAMA5 CFC1 PKD1 CFC1B	2.46e-04	100	105	4	25807483
Pubmed	Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses.	EVI2A CSF1R	2.50e-04	8	105	2	1643308
Pubmed	M-CSF induces the stable interaction of cFms with alphaVbeta3 integrin in osteoclasts.	CBL CSF1R	2.50e-04	8	105	2	16600665
Pubmed	Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins.	PTCRA PKD1	2.50e-04	8	105	2	22795130
Pubmed	Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.	TBL1Y TBL1XR1	2.50e-04	8	105	2	23770565
Pubmed	A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.	TBL1Y TBL1XR1	2.50e-04	8	105	2	16127449
Pubmed	Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.	CFC1 CFC1B	2.50e-04	8	105	2	21419113
Pubmed	Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.	SLC12A3 CNTNAP2	2.50e-04	8	105	2	18496130
Pubmed	CSF-1 stimulation induces the formation of a multiprotein complex including CSF-1 receptor, c-Cbl, PI 3-kinase, Crk-II and Grb2.	CBL CSF1R	2.50e-04	8	105	2	9178909
Pubmed	Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.	LAMA5 COL18A1	2.50e-04	8	105	2	19651211
Pubmed	Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.	CFC1 CFC1B	2.50e-04	8	105	2	15736223
Pubmed	NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.	CTRB2 CPA1 CTRB1	2.82e-04	42	105	3	37353485
Pubmed	Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells.	NEUROG1 NUMB	3.21e-04	9	105	2	20233719
Pubmed	Murine models of polycystic kidney disease: molecular and therapeutic insights.	NPHP3 PKD1	3.21e-04	9	105	2	14600027
Pubmed	Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro.	COL18A1 CSPG4	3.21e-04	9	105	2	23320101
Pubmed	Expression of discoidin domain receptor 1 during mouse brain development follows the progress of myelination.	DDR1 CSPG4	3.21e-04	9	105	2	16603319
Interaction	TOP3B interactions	TEAD2 MORN1 SZT2 SAMD4B KHNYN KDM3B LAMA5 TNRC6B NCLN RALGAPA2 TRAF4 AATK SLC2A4RG CELSR3 CSPG4 HPS6 PKD1 OSBPL5 STRN4 HERC2 TJP3	1.04e-05	1470	101	21	int:TOP3B
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	DDR1 AATK CSF1R	4.36e-04	40	67	3	321
Coexpression	TABULA_MURIS_SENIS_PANCREAS_LEUKOCYTE_AGEING	PRSS2 CTRB2 CPA1 CPB1 CTRB1	1.72e-06	50	105	5	MM3814
Coexpression	DESCARTES_MAIN_FETAL_ACINAR_CELLS	CTRB2 CPA1 CPB1 CTRB1 KLK1	4.30e-06	60	105	5	M40129
Coexpression	GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_DN	TGM3 FAP CELSR3 NUMB RHBDD3 FERMT2 TJP3	1.44e-05	196	105	7	M5791
Coexpression	DESCARTES_FETAL_PANCREAS_ACINAR_CELLS	CTRB2 CPA1 CPB1 CTRB1 KLK1	3.14e-05	90	105	5	M40267
Coexpression	GAO_LARGE_INTESTINE_ADULT_CA_ENTEROENDOCRINE_CELLS	CPB1 TAF6L TGM3 FAP CFC1 ALPK3 PAM SEZ6	3.78e-05	312	105	8	M39161
Coexpression	KIM_WT1_TARGETS_12HR_UP	DDR1 TAF6L MTUS1 CSPG4 FERMT2 CREB3L2	5.65e-05	166	105	6	M15535
CoexpressionAtlas	pancreas	PRSS2 CTRB2 CPA1 CPB1 CFC1 CTRB1 KLK1	5.13e-08	70	104	7	pancreas
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 PTCRA MUC19 CPA1 CPB1 CTRB1 KLK1	8.36e-09	175	104	8	7329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 MUC19 CPA1 CPB1 CTRB1 KLK1	1.05e-07	161	104	7	b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 MUC19 CPA1 CPB1 CTRB1 KLK1	1.05e-07	161	104	7	f7a89c481f789f624102857be722c95fbeb47595
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	1.10e-07	97	104	6	16947da747504c2edb9f2e7ee6f05babda0fae60
ToppCell	droplet-Pancreas-Exocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 DIO2 CTRB1 KLK1	1.24e-07	165	104	7	c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 SLC16A13 PPM1E TRAF4 MVB12A KLK1 TJP3	1.52e-07	170	104	7	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 SLC16A13 PPM1E TRAF4 MVB12A KLK1 TJP3	1.52e-07	170	104	7	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 RPS6KB1 CPA1 CPB1 CTRB1 KLK1	1.78e-07	174	104	7	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 RPS6KB1 CPA1 CPB1 CTRB1 KLK1	1.78e-07	174	104	7	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 COL18A1 CTRB1 KLK1	2.41e-07	182	104	7	45faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 COL18A1 CTRB1 KLK1	2.89e-07	187	104	7	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	facs-Pancreas-Exocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 COL18A1 CTRB1 KLK1	3.58e-07	193	104	7	c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	6.43e-07	70	104	5	26178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	6.43e-07	70	104	5	5720505ef03d65c73028616c808420e282823bde
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	7.13e-07	133	104	6	91e4556658e49f92946d48b194df64c5fc5758fe
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	1.62e-06	153	104	6	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E SLC12A3 GPR150 SLPI KLK1	1.88e-06	157	104	6	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E SLC12A3 GPR150 SLPI KLK1	1.88e-06	157	104	6	66a191cef4aa00811bb04462310d012610006f85
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	2.25e-06	162	104	6	922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCell	facs-Heart-LV-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 SLPI CTRB1 KLK1	2.33e-06	163	104	6	648d5439811b64412bc4678646f216105b90b9a1
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	2.50e-06	165	104	6	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	2.59e-06	166	104	6	b7f303203068b205f382788815df487a0ea148ed
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	PRSS2 CTRB2 CPA1 CPB1 CFC1 CTRB1	2.78e-06	168	104	6	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 PPM1E TRAF4 MVB12A KLK1 TJP3	3.18e-06	172	104	6	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 PPM1E TRAF4 MVB12A KLK1 TJP3	3.18e-06	172	104	6	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.29e-06	173	104	6	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	5b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	a6e73a40b0d5356564a594053e772f9d061a5919
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.29e-06	173	104	6	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	1edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.29e-06	173	104	6	c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.52e-06	175	104	6	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.63e-06	176	104	6	60740f676db5d259ef3046bd5bc7b7b14924ecee
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.63e-06	176	104	6	12bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCell	Severe_COVID-19-Myeloid-Neutrophil\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TNFSF14 RALGAPA2 CSRNP1 TGM3 FAP SLPI	3.75e-06	177	104	6	a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 CPB1 PKHD1L1 CFC1 SLPI CFC1B	3.75e-06	177	104	6	0912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	3.88e-06	178	104	6	415a02ad14df9deba988990118b00fb84ee524a8
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	4.01e-06	179	104	6	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	facs-Pancreas-Exocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 MUC19 CPA1 CPB1 CTRB1 KLK1	4.14e-06	180	104	6	72310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	4.27e-06	181	104	6	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	4.41e-06	182	104	6	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 TEAD2 CPA1 CPB1 CTRB1 KLK1	4.41e-06	182	104	6	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1 BAIAP2L2	4.41e-06	182	104	6	b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1 BAIAP2L2	4.41e-06	182	104	6	cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC16 CPA1 CPB1 PKHD1L1 CFC1 SLPI	4.55e-06	183	104	6	9d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC16 CPA1 CPB1 PKHD1L1 CFC1 SLPI	4.55e-06	183	104	6	c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCell	facs-Thymus\|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 PTCRA CPA1 CPB1 TRAF4 CTRB1	4.69e-06	184	104	6	58beef66bbbde2479ec69dfef392d5941cedf230
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 SLC12A3 CTRB1 KLK1	4.99e-06	186	104	6	7380af16e537cc49a2bb24ac50663d13c38459a7
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 SLC12A3 CTRB1 KLK1	4.99e-06	186	104	6	d56ccbe26bfddba0e2c54e7c7a5ca7f46fd3d891
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	5.04e-06	106	104	5	3aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	5.04e-06	106	104	5	c890c838785dfeda30f3b563194da9cfb49b157a
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 PAM CTRB1 KLK1	5.15e-06	187	104	6	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	NS-critical-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DDR1 MUC16 TRAF4 MTUS1 SLPI TJP3	7.35e-06	199	104	6	b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell	Bronchial-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DDR1 MUC16 ADGRV1 TRAF4 SLPI TJP3	7.56e-06	200	104	6	d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	2.55e-05	148	104	5	bbf4933582b50b3412c805de5ed137107c996236
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	2.55e-05	148	104	5	6543860e3207a7de92a35bb6004be51287582f7a
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	2.55e-05	148	104	5	79e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCell	facs-Aorta-Heart-3m-Epithelial-epithelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 FTCD CTRB1	2.80e-05	151	104	5	0de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCell	facs-Aorta-Heart-3m-Epithelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 FTCD CTRB1	2.80e-05	151	104	5	20b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCell	facs-Aorta-Heart-3m-Epithelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 FTCD CTRB1	2.80e-05	151	104	5	bee48137d1f5f27a24571a59c835284651d38538
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 TGM3 CTRB1	2.80e-05	151	104	5	a306e8dac653bc785d805d8d2d94feec3cb01727
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HK3 COQ6 AATK C1QTNF7 AGAP2	2.89e-05	152	104	5	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	facs-Lung-EPCAM-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TNFSF14 CSRNP1 SLPI CTRB1	3.70e-05	160	104	5	b73f07a0088936fbc3656a05710a67f38b4ae551
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TNFSF14 CSRNP1 SLPI CTRB1	3.70e-05	160	104	5	b88876a58fea2066468e74dcc439c8561130a910
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A TBL1XR1 CD163 CSF1R	3.92e-05	162	104	5	71d7849108a1b59beff40e46000172c45a2f5439
ToppCell	facs-SCAT-Fat-24m\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	3.92e-05	162	104	5	b824f30c723c9c7d8e8c8a8dc3f88d4eed29dd67
ToppCell	facs-Kidney-nan-24m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 EVI2A CPA1 CPB1 CTRB1	3.92e-05	162	104	5	f223ea00cf7fbc25e6d5a946ee1ff05f7d4abb06
ToppCell	facs-SCAT-Fat-24m-Epithelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	4.04e-05	163	104	5	9fd2e495efb6c447cdc52efdb3b695cb2fa8b914
ToppCell	facs-SCAT-Fat-24m-Epithelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	4.04e-05	163	104	5	ade2f59bca0ab0c4856202f980464f3287bddd24
ToppCell	facs-SCAT-Fat-24m-Epithelial-epithelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	4.04e-05	163	104	5	aaf5d96bab1957c7bde84c741c7f2fb86ef41e8b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 SP8 CNTNAP2 PAM SEZ6	4.28e-05	165	104	5	c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCell	droplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1E EVI2A TRAF4 MVB12A KLK1	4.41e-05	166	104	5	6e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPM1E EVI2A TRAF4 MVB12A KLK1	4.41e-05	166	104	5	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	facs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	4.41e-05	166	104	5	c02c2a68d61dbd7ed086d9b02cfcb1778b8a8656
ToppCell	facs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 CTRB1 KLK1	4.41e-05	166	104	5	20c24a9d2eb67a20e5154d25656da14186034f02
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1E EVI2A TRAF4 MVB12A KLK1	4.41e-05	166	104	5	4fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPM1E EVI2A TRAF4 MVB12A KLK1	4.41e-05	166	104	5	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	facs-Lung-Endomucin-24m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 FTCD CTRB1	4.41e-05	166	104	5	64a0762eb9cafb6a079df296ed677c8e0ae0efa7
ToppCell	droplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 FCHO1 TRAF4 SLPI KLK1	4.54e-05	167	104	5	1248f809afbcccb42ce9e29cfe6fa1f6f6b65005
ToppCell	droplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 FCHO1 TRAF4 SLPI KLK1	4.54e-05	167	104	5	a66552667aa6e8992c159df27a57c2e8ae14a9ce
ToppCell	facs-Heart-RV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	4.67e-05	168	104	5	8ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CD163 SLC12A3 ARHGAP45	4.67e-05	168	104	5	29a6c3ba69e03ccb19efb8ac177b9a162dc1ea43
ToppCell	facs-Heart-RV-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	4.67e-05	168	104	5	c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CD163 SLC12A3 ARHGAP45	4.67e-05	168	104	5	4297be958a4754677df7cf73feba19b0d76f1b4a
ToppCell	facs-Heart-RV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	4.67e-05	168	104	5	a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCell	droplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF14 EVI2A CSF1R SLPI ARHGAP45	4.67e-05	168	104	5	5946204d42307391bc2160abe12850815f350aea
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF14 CPB1 SSPOP CTRB1 ARHGAP45	5.08e-05	171	104	5	872b3b33cd3893d63c45617db0269692430b0e8b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 PPM1E TRAF4 GPR150 KLK1	5.08e-05	171	104	5	2dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 PPM1E TRAF4 GPR150 KLK1	5.08e-05	171	104	5	2aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCell	droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E TAF6L TRAF4 KLK1	5.36e-05	173	104	5	1b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E TRAF4 GPR150 KLK1	5.36e-05	173	104	5	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E TAF6L TRAF4 KLK1	5.36e-05	173	104	5	c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 PPM1E TRAF4 GPR150 KLK1	5.36e-05	173	104	5	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	facs-Heart-LA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	5.51e-05	174	104	5	30c083fe4711735e83dccfd00fcd746ae673d353
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	5.51e-05	174	104	5	46d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 EVI2A CD163 CSF1R ARHGAP45	5.51e-05	174	104	5	1802a52552256d1e25d8b328ba62dcfe41671900
ToppCell	facs-Heart-LV-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CPB1 SLPI CTRB1	5.51e-05	174	104	5	f0974f4e94a9719f9b96820e70c23b6c6c0f02fe
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CPA1 CD163 SLC12A3 ARHGAP45	5.51e-05	174	104	5	84f2ffe867f22d2fa79f28737a0aa42bdf2f4804
Computational	Neighborhood of SERPINI2	PRSS2 CPA1 CPB1 PRSS3P2 CTRB1	2.86e-07	25	63	5	GNF2_SERPINI2
Computational	Neighborhood of SPINK1	PRSS2 CPA1 CPB1 PRSS3P2 CTRB1	4.30e-07	27	63	5	GNF2_SPINK1
Drug	Es 6864	PRSS2 CTRB2 CTRB1 KLK1	1.37e-07	11	105	4	CID003082786
Drug	procyanidin B-5 3,3'-di-O-gallate	CTRB2 CPA1 CTRB1 KLK1	5.61e-07	15	105	4	CID003086518
Drug	S2266	PRSS2 TNFSF14 CTRB2 CTRB1 KLK1	1.10e-06	40	105	5	CID000122333
Drug	AC1Q6PMM	CTRB2 CPB1 COL18A1 CTRB1 KLK1	1.10e-06	40	105	5	CID000003211
Drug	AC1LAR7G	PRSS2 CTRB2 COL18A1 CTRB1 KLK1	1.24e-06	41	105	5	CID000493598
Drug	N-benzoyltyrosine butylamide	PRSS2 CTRB2 CTRB1	1.89e-06	6	105	3	CID000125261
Drug	N-benzoyl-L-tyrosine thiobenzyl ester	PRSS2 CTRB2 CTRB1	1.89e-06	6	105	3	CID000191444
Drug	N,N-dimethylglycylbenzocaine	PRSS2 CTRB2 CTRB1	1.89e-06	6	105	3	CID000188251
Drug	2-azidoatrazine	PRSS2 CTRB2 CTRB1	1.89e-06	6	105	3	CID003032432
Drug	p-aminobenzamidine	PRSS2 TNFSF14 CTRB2 SLC2A4RG CTRB1 KLK1	2.04e-06	81	105	6	CID000001725
Drug	AC1L2Q8B	PRSS2 CTRB2 CTRB1 KLK1	2.93e-06	22	105	4	CID000126377
Drug	Fp-O	PRSS2 CTRB2 FAP SLPI CTRB1 KLK1	3.11e-06	87	105	6	CID000024267
Drug	Es 8891	CTRB2 CTRB1 KLK1	3.29e-06	7	105	3	CID000195623
Drug	pentaammineaquocobalt(III) tetrafluoroborate	PRSS2 CTRB2 CTRB1	3.29e-06	7	105	3	CID000412963
Drug	Cbz-phe-arg-chn2	PRSS2 CTRB2 CTRB1	3.29e-06	7	105	3	CID005492392
Drug	AAPCK	CTRB2 CTRB1 KLK1	3.29e-06	7	105	3	CID000128055
Drug	AC1MCHYW	PRSS2 CTRB2 CTRB1	5.25e-06	8	105	3	CID002770087
Drug	Bio-Phe-CH2Cl	PRSS2 CTRB2 CTRB1	5.25e-06	8	105	3	CID000083924
Drug	Bio-Arg-CH2Cl	PRSS2 CTRB2 CTRB1	5.25e-06	8	105	3	CID000083923
Drug	3,5-bis-trifluoromethylphenylboronic acid	PRSS2 CTRB2 CTRB1	5.25e-06	8	105	3	CID000156265
Drug	N-benzoyl-L-arginine	PRSS2 CTRB2 CPB1 CTRB1 KLK1	7.15e-06	58	105	5	CID000097369
Drug	FK-401	PRSS2 CTRB2 CTRB1	7.85e-06	9	105	3	CID000135041
Drug	tlmE	PRSS2 CTRB2 CTRB1	7.85e-06	9	105	3	CID000188322
Drug	5-amino-2-nitrobenzoic acid	CTRB2 CTRB1 KLK1	7.85e-06	9	105	3	CID000083298
Drug	Lb I	PRSS2 CTRB2 PAM CTRB1	8.03e-06	28	105	4	CID000161844
Drug	o-iodosobenzoic acid	PRSS2 CTRB2 CPA1 CPB1 CTRB1	9.18e-06	61	105	5	CID000067537
Drug	RD4-6205	PRSS2 CTRB2 CTRB1	1.12e-05	10	105	3	CID003002865
Drug	BAEE	PRSS2 CTRB2 CPB1 CTRB1 KLK1	1.16e-05	64	105	5	CID000123880
Drug	26-nor-25-doxylcholestanol	PRSS2 CTRB2 CTRB1	1.53e-05	11	105	3	CID000125890
Drug	benzyl sulfonate	CTRB2 CPA1 CTRB1	1.53e-05	11	105	3	CID000007532
Drug	tetrazol-5-imine	CTRB2 CPA1 CTRB1	1.53e-05	11	105	3	CID000407223
Drug	NSC187724	PRSS2 CTRB2 CTRB1 KLK1	2.00e-05	35	105	4	CID000426387
Drug	BOCPheONP	CTRB2 CTRB1	2.11e-05	2	105	2	CID000111308
Drug	MPM-06	CTRB2 CTRB1	2.11e-05	2	105	2	CID000161546
Drug	NSC-374899	CTRB2 CTRB1	2.11e-05	2	105	2	CID000435726
Drug	methylbenzenebutanoate	CTRB2 CTRB1	2.11e-05	2	105	2	CID000281254
Drug	Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu	CTRB2 CTRB1	2.11e-05	2	105	2	CID004418081
Drug	c189	CTRB2 CTRB1	2.11e-05	2	105	2	CID000248048
Drug	dansyl-D-arginine methyl ester	CTRB2 CTRB1	2.11e-05	2	105	2	CID000191369
Drug	methyl 6-phenylhexanoate	CTRB2 CTRB1	2.11e-05	2	105	2	CID011820300
Drug	5-aminotetrazole	CTRB2 CTRB1	2.11e-05	2	105	2	CID000020467
Drug	2-bromoisobutyric acid	CTRB2 CTRB1	2.11e-05	2	105	2	CID000074924
Drug	p-toluamidine	CTRB2 CTRB1	2.11e-05	2	105	2	CID000122753
Drug	N-acetyl-alpha-azaphenylalanine phenyl ester	CTRB2 CTRB1	2.11e-05	2	105	2	CID000191275
Drug	isobutyl sulfide	CTRB2 CTRB1	2.11e-05	2	105	2	CID000011607
Drug	AC1NRA23	PRSS2 CTRB2 SLPI CTRB1 KLK1	2.22e-05	73	105	5	CID005287657
Drug	BTEE	PRSS2 CTRB2 CTRB1 KLK1	2.25e-05	36	105	4	CID000077033
Drug	diisopropyl	PRSS2 CTRB2 CTRB1 KLK1	2.25e-05	36	105	4	CID000006589
Drug	1 PI	PRSS2 CTRB2 SLPI CTRB1	2.25e-05	36	105	4	CID005287454
Drug	phenyl 4-guanidinobenzoate	PRSS2 CTRB2 CTRB1	2.64e-05	13	105	3	CID003015798
Drug	Pd-Ti	PRSS2 CTRB2 CTRB1	2.64e-05	13	105	3	CID006452040
Drug	Lga-afc	CTRB2 CTRB1 KLK1	2.64e-05	13	105	3	CID003081120
Drug	phenylmethylsulfonyl fluoride	PRSS2 CTRB2 CPB1 SLC2A4RG ACTL8 SLPI CTRB1 KLK1	3.02e-05	263	105	8	CID000004784
Drug	urinastatin	PRSS2 CTRB2 SLPI CTRB1 KLK1	3.26e-05	79	105	5	CID000105102
Drug	Tyr-D-Ala-Phe-Phe-NH2	CTRB2 CPA1 CTRB1	3.34e-05	14	105	3	CID004584008
Drug	AC1Q5JSU	PRSS2 CTRB2 CTRB1	3.34e-05	14	105	3	CID000093061
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	SZT2 CBL CSF1R MIA2 ACTL8 SLPI RHBDD3	3.75e-05	198	105	7	2845_UP
Drug	Bromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CBL CSF1R MIA2 CELSR3 PDE4DIP CNTNAP2 ARHGAP45	3.75e-05	198	105	7	7457_UP
Drug	NPGB	PRSS2 CTRB2 CTRB1 KLK1	3.79e-05	41	105	4	CID000030744
Drug	rotenone; Up 200; 1uM; PC3; HT_HG-U133A	MORN1 CSF1R CELSR3 MTUS1 CSPG4 PDE4DIP ALPK3	3.87e-05	199	105	7	5920_UP
Drug	BTPNA	PRSS2 CTRB2 CTRB1	4.17e-05	15	105	3	CID000188992
Drug	ONO-3307	PRSS2 CTRB2 CTRB1	4.17e-05	15	105	3	CID000127139
Drug	N-benzoyl-L-tyrosine	PRSS2 CTRB2 CTRB1	4.17e-05	15	105	3	CID000151021
Drug	diphenylcarbamyl chloride	PRSS2 CTRB2 CTRB1	5.11e-05	16	105	3	CID000065741
Drug	CCK-9	CTRB2 CTRB1 KLK1	5.11e-05	16	105	3	CID000163781
Drug	chloropicrin	PRSS2 HK3 CTRB2 CPA1 CTRB1	6.10e-05	90	105	5	CID000006423
Drug	De 1	PRSS2 CTRB2 CTRB1	6.18e-05	17	105	3	CID006453604
Drug	benzamidine	PRSS2 TNFSF14 CTRB2 SLC2A4RG CTRB1 KLK1	6.22e-05	147	105	6	CID000002332
Drug	N-acetylbenzotriazole	CTRB2 CTRB1	6.30e-05	3	105	2	CID000087784
Drug	photophor	CTRB2 CTRB1	6.30e-05	3	105	2	CID000014780
Drug	dibutyl iodomethaneboronate	CTRB2 CTRB1	6.30e-05	3	105	2	CID000098591
Drug	zinc;dipicolinate	CTRB2 CTRB1	6.30e-05	3	105	2	CID004309911
Drug	2-oxobut-3-ynoate	CTRB2 CTRB1	6.30e-05	3	105	2	CID000171547
Drug	AFMeq	CTRB2 CTRB1	6.30e-05	3	105	2	CID000194069
Drug	Bz-Cti-otbu	CTRB2 CTRB1	6.30e-05	3	105	2	CID006452691
Drug	n-(2-oxoethyl)benzamide	CTRB2 CTRB1	6.30e-05	3	105	2	CID000188995
Drug	AC1L49DM	CTRB2 CTRB1	6.30e-05	3	105	2	CID000152933
Drug	c140	CTRB2 CTRB1	6.30e-05	3	105	2	CID002783250
Drug	Benzamidomethaneboronic acid	CTRB2 CTRB1	6.30e-05	3	105	2	CID000127677
Drug	phenyl hippurate	CTRB2 CTRB1	6.30e-05	3	105	2	CID000076323
Drug	FK-386	CTRB2 CTRB1	6.30e-05	3	105	2	CID000135044
Drug	FK-375	CTRB2 CTRB1	6.30e-05	3	105	2	CID000135042
Drug	carbostyril-124	CTRB2 CTRB1	6.30e-05	3	105	2	CID000088277
Drug	N-trifluoroacetyl-4-fluorophenylalanine	CTRB2 CTRB1	6.30e-05	3	105	2	CID000328214
Drug	C18 4	CTRB2 CTRB1	6.30e-05	3	105	2	CID000077248
Drug	taraxastane	CTRB2 CTRB1	6.30e-05	3	105	2	CID006429404
Drug	Phe-phe-ome	CTRB2 CTRB1	6.30e-05	3	105	2	CID000151728
Drug	phenylethaneboronic acid	CTRB2 CTRB1	6.30e-05	3	105	2	CID000065389
Drug	3-amino-2-pyridone	CTRB2 CTRB1	6.30e-05	3	105	2	CID000322353
Drug	ASA-BMPA	CTRB2 CTRB1	6.30e-05	3	105	2	CID003035649
Drug	p-nitrophenyl benzoate	CTRB2 CTRB1	6.30e-05	3	105	2	CID000070396
Drug	Z-Phe-OMe	CTRB2 CTRB1	6.30e-05	3	105	2	CID003082435
Drug	3-methylcoumarin	CTRB2 CTRB1	6.30e-05	3	105	2	CID000017130
Drug	2-propyl methylphosphonochloridate	CTRB2 CTRB1	6.30e-05	3	105	2	CID000102124
Drug	FK-316	CTRB2 CTRB1	6.30e-05	3	105	2	CID000133688
Drug	AC1L19T8	CTRB2 CTRB1	6.30e-05	3	105	2	CID000000694
Drug	Marinostatin D	CTRB2 CTRB1	6.30e-05	3	105	2	CID000132206
Drug	1FD7	CTRB2 CTRB1	6.30e-05	3	105	2	CID000445579
Drug	Glt-leu-phe-nh-meq	CTRB2 CTRB1	6.30e-05	3	105	2	CID000194914
Drug	AC1L4Z4F	CTRB2 CTRB1	6.30e-05	3	105	2	CID000194913
Disease	trypsin-2 measurement	PRSS2 CTRB2 CTRB1	6.68e-06	11	103	3	EFO_0008305
Disease	level of chymotrypsinogen B2 in blood serum	CTRB2 CTRB1	1.21e-05	2	103	2	OBA_2041192
Disease	level of carboxypeptidase A1 in blood serum	CTRB2 CPA1	3.61e-05	3	103	2	OBA_2041112
Disease	double outlet right ventricle (implicated_via_orthology)	CFC1 CFC1B	3.61e-05	3	103	2	DOID:6406 (implicated_via_orthology)
Disease	chymotrypsinogen B measurement	CTRB2 CTRB1	3.61e-05	3	103	2	EFO_0801477
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1	3.61e-05	3	103	2	DOID:0050155 (implicated_via_orthology)
Disease	dextro-looped transposition of the great arteries (implicated_via_orthology)	CFC1 CFC1B	7.21e-05	4	103	2	DOID:0060770 (implicated_via_orthology)
Disease	right atrial isomerism (implicated_via_orthology)	CFC1 CFC1B	7.21e-05	4	103	2	DOID:0060856 (implicated_via_orthology)
Disease	glucose metabolism disease (implicated_via_orthology)	HK3 RPS6KB1 DIO2	1.27e-04	28	103	3	DOID:4194 (implicated_via_orthology)
Disease	acute lymphoblastic leukemia (is_marker_for)	KDM3B TM9SF2 CSPG4	2.28e-04	34	103	3	DOID:9952 (is_marker_for)
Disease	Hereditary pancreatitis	PRSS2 CPA1	2.51e-04	7	103	2	C0238339
Disease	smoking status measurement, low density lipoprotein cholesterol measurement	CNTNAP2 CREB3L2	2.51e-04	7	103	2	EFO_0004611, EFO_0006527
Disease	pancreatitis (biomarker_via_orthology)	CTRB2 CTRB1 KLK1	3.45e-04	39	103	3	DOID:4989 (biomarker_via_orthology)
Disease	Mastocytosis	FTCD TBL1XR1 PDE4DIP	3.45e-04	39	103	3	EFO_0009001
Disease	carboxypeptidase B measurement	CTRB2 CPB1	4.28e-04	9	103	2	EFO_0801453
Disease	Pancreatitis, Chronic	PRSS2 CPA1	4.28e-04	9	103	2	C0149521
Disease	urea measurement	TGM3 CNTNAP2	5.33e-04	10	103	2	EFO_0011005
Disease	osteosarcoma (is_marker_for)	DDR1 CBL	6.50e-04	11	103	2	DOID:3347 (is_marker_for)
Disease	visceral heterotaxy (is_implicated_in)	CFC1 CFC1B	7.78e-04	12	103	2	DOID:0050545 (is_implicated_in)
Disease	Hematologic Neoplasms	CBL CSF1R	7.78e-04	12	103	2	C0376545
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	NPHP3 PKD1	1.07e-03	14	103	2	DOID:898 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	MUC19 LCT CD163 NPHP3 CSF1R OSBPL5 CNTNAP2 STRN4 ARHGAP45 TJP3	1.25e-03	904	103	10	EFO_0004736
Disease	Sclerocystic Ovaries	TEAD2 MORN1 PTCRA TNRC6B	1.65e-03	144	103	4	C1136382
Disease	Polycystic Ovary Syndrome	TEAD2 MORN1 PTCRA TNRC6B	1.65e-03	144	103	4	C0032460
Disease	diet measurement, body mass index	TBL1XR1 CNTNAP2	2.20e-03	20	103	2	EFO_0004340, EFO_0008111
Disease	Renal glomerular disease	NPHP3 SLC12A3	2.91e-03	23	103	2	C0268731
Disease	Glomerulopathy Assessment	NPHP3 SLC12A3	2.91e-03	23	103	2	C4521256
Disease	Sjogren's syndrome (is_marker_for)	MUC19 MUC16	3.17e-03	24	103	2	DOID:12894 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSPGGQWLVSGSDDG	BOP1	421	Q14137
DDFPAGTLCATTGWG	CTRB2	146	Q6GPI1
WFSGLLGSSSGVPEA	CCDC116	241	Q8IYX3
SLAAFPAWGTQDEGT	CSPG4	211	Q6UVK1
GSGFLKAGTAGWNEP	ACTL8	11	Q9H568
NWDAGFGLSGASSNP	CPA1	256	P15085
SSDGDGAWCPAGSVF	DDR1	66	Q08345
GALSVAWTTGYAPGL	ADGRV1	4916	Q8WXG9
FCWVPGSDPGTFDGS	RTL10	96	Q7L3V2
GSDPGTFDGSPWLLD	RTL10	101	Q7L3V2
AGAWRTGEAAASAGP	ALPK3	181	Q96L96
SPGSATLLSSFGAWD	COQ6	91	Q9Y2Z9
PSGKFITQWGEESSG	PAM	661	P19021
LWISTSSAGAGGAEP	AGAP2	76	Q99490
SHFGEVTGSAEGWGP	CFC1B	56	P0CG36
SHFGEVTGSAEGWGP	CFC1	56	P0CG37
PSRGWQSLSFDGGAF	PRODH2	91	Q9UF12
PGWGSREAAGSASAA	RILP	11	Q96NA2
DAFGVAPWLSLGADS	NCLN	226	Q969V3
APWLSLGADSNGSGV	NCLN	231	Q969V3
WSGDTFSGQFVLGEP	MORN1	81	Q5T089
AGGSGRLSASWEPLS	FCHO1	826	O14526
ASEWLGSPGTLGGTS	MUC16	386	Q8WXI7
NGTDAAFLAGPGSSW	P2RY1	11	P47900
AFLAGPGSSWGNSTV	P2RY1	16	P47900
GLDSPIWFSAGNGSA	PTCRA	56	Q6ISU1
PSDGWAIPGDSSLSF	DIO2	166	Q92813
GFPLSGAASWTLGRS	ARHGAP45	76	Q92619
SGLGLWEDTPKSGGS	GIGYF1	836	O75420
SGWGSIEPENFSFPD	KLK1	156	P06870
WGSGAAAASPLSDPS	NEUROG1	186	Q92886
PGQKVGSSFGLTWDA	MTUS1	401	Q9ULD2
ADIFGTSDPGGLASW	CSRNP1	426	Q96S65
PDDWTLSAGGSGTIY	HERC2	3941	O95714
GKLEGSSASGWFPEA	BAIAP2L2	366	Q6UXY1
SGASLDVGFGWGISD	MUC19	201	Q7Z5P9
FPSWEALFSGSEGPL	COL18A1	1651	P39060
GDFLASGLWPAESDT	EVI2A	181	P22794
LVWFPGGAFKTGSAS	CES5A	141	Q6NT32
DSWVFGGIDPQSGAA	FOLH1B	71	Q9HBA9
SNGSDGGEASRGPWK	KDM3B	311	Q7LBC6
FSPGDFWGRGASAST	RPS6KB1	451	P23443
TFPEGFLWGASTGAF	LCT	381	P09848
WLSLGGGLAQSDTSP	PLA2G12B	11	Q9BX93
GDPWLTDGSYLDGTG	LAMA5	2936	O15230
AGGSLTGWHPDSAAV	RALGAPA2	916	Q2PPJ7
SVEWGSFSDDGALGP	HK3	271	P52790
GTDSAPLAGLAWSSA	MVB12A	6	Q96EY5
VGPTAEWNGDGSGSL	KLC2	526	Q9H0B6
SLPEWSGAGEFPTAF	PPM1E	616	Q8WY54
VGSGSWAFIPISAGA	CSF1R	491	P07333
TDWGFESPLFQDTGG	BPIFC	116	Q8NFQ6
SPSGREASLWSSGFG	GPAT2	16	Q6NUI2
GAPGGTAVWATSLEA	CCDC78	31	A2IDD5
EASSGQGPGALASWE	KHNYN	196	O15037
QGPGALASWEGRSSA	KHNYN	201	O15037
ASSSFGWLSLDGDPT	CBL	796	P22681
NKRGGAGGWSPSDSD	CNTNAP2	66	Q9UHC6
RGAGAGAAGPWFSSE	CELSR3	1336	Q9NYQ7
AWFGDSALSEGNPGI	FERMT2	206	Q96AC1
EAPVGPWGSAALGTF	HPS6	306	Q86YV9
PWGSAALGTFQGTLA	HPS6	311	Q86YV9
SSNFGEGSGPIWFDD	CD163	211	Q86VB7
VLTGNFPWEAASGAD	SBK1	246	Q52WX2
WPLTQDLDSGFASGS	PPP4R1L	291	Q9P1A2
GATTIYPAAGGSDDW	CPB1	351	P15086
GLFSDPGWADSLFSG	C1QTNF7	256	Q9BXJ2
DDFPAGTLCATTGWG	CTRB1	146	P17538
SSSPGSAGELGGWDR	CREB3L2	441	Q70SY1
DFGPSSFVPSWGATA	FTCD	161	O95954
GSGTWAYSAPDLLGA	PKD1	3791	P98161
EEGSGSSALFWTPSG	OSBPL5	611	Q9H0X9
PSSAVSGVKEWFGLG	MIA2	216	Q96PC5
EWGQSSGAASPGLFQ	NUMB	416	P49757
PWDSLLFQESSSGGG	TAF6L	396	Q9Y6J9
FGDWSGAPSLKDLGG	SZT2	1166	Q5T011
ISGWGNTLSSGADYP	PRSS3P2	141	Q8NHM4
ATFGNSWRLPGSESG	SSPOP	346	A2VEC9
GTLAPWAVEGSGKSF	SLPI	16	P03973
SPNGSTAEEGGGFAW	AATK	1286	Q6ZMQ8
YWTGGALGSEPSIGS	NPHP3	231	Q7Z494
SSGPAGDWEGEGLSA	GPR150	321	Q8NGU9
GTDVSFEGGTLGSAW	MEX3C	411	Q5U5Q3
FEGGTLGSAWLSSNP	MEX3C	416	Q5U5Q3
GNFWFGDTLPSVGSE	MEX3C	476	Q5U5Q3
GEEGLGTAWPSAANA	SSTR4	11	P31391
AGAALDDGSGWTGSE	TEAD2	6	Q15562
AWNPVSDLLASGSGD	TBL1XR1	176	Q9BZK7
LGAAGEVGSAGASSW	SP8	196	Q8IXZ3
KAVFPLSNGSSGGWS	TGM3	71	Q08188
SEAGLDWAGASFSPG	RHBDD3	271	Q9Y3P4
ESRTGWAGGFFVSTP	FAP	341	Q12884
GPDASPDASFGKQWS	PITPNM1	296	O00562
GLLSGSGWALTFAPT	SLC16A13	111	Q7RTY0
SDLGAPRTWTGAAAG	SLC2A4RG	66	Q9NR83
WAFGSNSLPIAGSVG	SAMD4B	551	Q5PRF9
ANSSLTGSGGPLLWE	TNFSF14	101	O43557
LWPFASAAGGGGSEA	TUSC2	11	O75896
ATLSPGASSRGWDDG	TEX264	241	Q9Y6I9
ASGVLNDTVTPGWGA	SLC12A3	401	P55017
WNFSGPEGSLDSPTD	SEZ6	246	Q53EL9
GLEGVGTIWPSSYSS	STH	66	Q8IWL8
GTWRGSLDESSLGFG	TRAF4	421	Q9BUZ4
ISGWGNTLSSGADYP	PRSS2	141	P07478
SSNFSWGGKSPPEEG	PKHD1L1	2181	Q86WI1
AWNPVSDLLASGSGD	TBL1Y	186	Q9BQ87
AGVSRAAGSPSGWEA	UNQ6494/PRO21346	51	Q6UXR6
GPGSSAGSNARAEFW	TJP3	561	O95049
LWGEGSSAAIPFGTL	TM9SF2	456	Q99805
SAAPGSLGYQWLSDG	TRAP1	221	Q12931
EGHGDAVWGLAFSPT	STRN4	541	Q9NRL3
GSSGADLAGASLWGP	TNRC6B	1781	Q9UPQ9
DEGWLSDGTGAFYSP	PDE4DIP	1416	Q5VU43