Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphoglycerate kinase activity

PGK1 PGK2

7.18e-062542GO:0004618
GeneOntologyMolecularFunctionphosphotransferase activity, carboxyl group as acceptor

PGK1 PGK2

2.15e-053542GO:0016774
GeneOntologyMolecularFunctionpoly(A) binding

PABPC3 PABPC4 PABPC1

6.50e-0529543GO:0008143
GeneOntologyMolecularFunctionpoly(U) RNA binding

PABPC3 PABPC4 PABPC1

1.05e-0434543GO:0008266
GeneOntologyMolecularFunctionpoly-purine tract binding

PABPC3 PABPC4 PABPC1

1.36e-0437543GO:0070717
GeneOntologyMolecularFunctionpoly-pyrimidine tract binding

PABPC3 PABPC4 PABPC1

1.59e-0439543GO:0008187
GeneOntologyMolecularFunctiontransmembrane-ephrin receptor activity

EPHA1 EPHA7

7.37e-0415542GO:0005005
GeneOntologyMolecularFunctiondiacylglycerol-dependent serine/threonine kinase activity

PRKD3 PRKD2

8.41e-0416542GO:0004697
GeneOntologyMolecularFunctiontransferase activity, transferring sulphur-containing groups

NDST1 SULT1B1 MOCOS

1.06e-0374543GO:0016782
GeneOntologyMolecularFunctionephrin receptor activity

EPHA1 EPHA7

1.19e-0319542GO:0005003
GeneOntologyCellularComponentmCRD-mediated mRNA stability complex

PABPC3 PABPC1

9.76e-056542GO:0106002
DomainPolyA

PABPC3 PABPC4 PABPC1

2.15e-075533SM00517
Domain-

PABPC3 PABPC4 PABPC1

2.15e-0755331.10.1900.10
DomainPABP

PABPC3 PABPC4 PABPC1

2.15e-075533PF00658
DomainPABC

PABPC3 PABPC4 PABPC1

2.15e-075533PS51309
DomainPABP_1234

PABPC3 PABPC4 PABPC1

2.15e-075533IPR006515
DomainPABP_HYD

PABPC3 PABPC4 PABPC1

2.15e-075533IPR002004
DomainPGLYCERATE_KINASE

PGK1 PGK2

7.90e-062532PS00111
DomainPhosphoglycerate_kinase_N

PGK1 PGK2

7.90e-062532IPR015824
DomainPhosphoglycerate_kinase_CS

PGK1 PGK2

7.90e-062532IPR015911
DomainPhosphoglycerate_kinase_C

PGK1 PGK2

7.90e-062532IPR015901
Domain-

PGK1 PGK2

7.90e-0625323.40.50.1270
Domain-

PGK1 PGK2

7.90e-0625323.40.50.1260
DomainPGK

PGK1 PGK2

7.90e-062532PF00162
DomainPhosphoglycerate_kinase

PGK1 PGK2

2.37e-053532IPR001576
DomainProtein_Kinase_C_mu-related

PRKD3 PRKD2

2.37e-053532IPR015727
DomainRRM_dom_euk

PABPC3 PABPC4 PABPC1

3.67e-0523533IPR003954
DomainRRM_1

PABPC3 PABPC4 PABPC1

3.67e-0523533SM00361
Domain-

DCAKD NDST1 SULT1B1 EIF4A2 MTREX POLQ DNAH8 HYDIN RAB27B

2.26e-047465393.40.50.300
DomainP-loop_NTPase

DCAKD NDST1 SULT1B1 EIF4A2 MTREX POLQ DNAH8 HYDIN RAB27B

5.77e-04848539IPR027417
DomainRECEPTOR_TYR_KIN_V_2

EPHA1 EPHA7

7.03e-0414532PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA1 EPHA7

7.03e-0414532PS00790
DomainEph_TM

EPHA1 EPHA7

7.03e-0414532IPR027936
DomainTyr_kinase_rcpt_V_CS

EPHA1 EPHA7

7.03e-0414532IPR001426
DomainEPH_lbd

EPHA1 EPHA7

7.03e-0414532SM00615
DomainEphrin_lbd

EPHA1 EPHA7

7.03e-0414532PF01404
DomainEphA2_TM

EPHA1 EPHA7

7.03e-0414532PF14575
DomainTyr_kinase_ephrin_rcpt

EPHA1 EPHA7

7.03e-0414532IPR016257
DomainEphrin_rcpt_lig-bd_dom

EPHA1 EPHA7

7.03e-0414532IPR001090
DomainEPH_LBD

EPHA1 EPHA7

7.03e-0414532PS51550
DomainDEAD/DEAH_box_helicase_dom

EIF4A2 MTREX POLQ

1.17e-0373533IPR011545
DomainDEAD

EIF4A2 MTREX POLQ

1.17e-0373533PF00270
DomainDAG/PE-bd

PRKD3 PRKD2

1.60e-0321532IPR020454
DomainEphrin_rec_like

EPHA1 EPHA7

2.27e-0325532SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHA1 EPHA7

2.27e-0325532IPR011641
DomainRRM_1

PABPC3 PABPC4 PABPC1 CSTF2T

2.86e-03208534PF00076
DomainRRM

PABPC3 PABPC4 PABPC1 CSTF2T

3.33e-03217534SM00360
DomainHelicase_C

EIF4A2 MTREX POLQ

3.48e-03107533PF00271
DomainHELICc

EIF4A2 MTREX POLQ

3.48e-03107533SM00490
DomainHelicase_C

EIF4A2 MTREX POLQ

3.57e-03108533IPR001650
DomainHELICASE_CTER

EIF4A2 MTREX POLQ

3.66e-03109533PS51194
DomainHELICASE_ATP_BIND_1

EIF4A2 MTREX POLQ

3.66e-03109533PS51192
DomainDEXDc

EIF4A2 MTREX POLQ

3.66e-03109533SM00487
DomainHelicase_ATP-bd

EIF4A2 MTREX POLQ

3.76e-03110533IPR014001
DomainRRM_dom

PABPC3 PABPC4 PABPC1 CSTF2T

3.91e-03227534IPR000504
DomainRRM

PABPC3 PABPC4 PABPC1 CSTF2T

4.09e-03230534PS50102
DomainSulfotransferase_dom

NDST1 SULT1B1

4.68e-0336532IPR000863
DomainSulfotransfer_1

NDST1 SULT1B1

4.68e-0336532PF00685
Domain-

PABPC3 PABPC4 PABPC1 CSTF2T

5.04e-032445343.30.70.330
PathwayWP_TRANSLATION_FACTORS

PABPC3 EIF4A2 EIF3E PABPC1

2.03e-0551454MM15881
PathwayREACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY

PABPC3 EIF4A2 PABPC1 EXOSC2

2.55e-0554454MM15089
PathwayBIOCARTA_EIF4_PATHWAY

PABPC3 EIF4A2 PABPC1

5.15e-0523453MM1470
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

PABPC3 EIF4A2 EIF3E PABPC1

5.32e-0565454MM15416
PathwayREACTOME_DEADENYLATION_OF_MRNA

PABPC3 EIF4A2 PABPC1

5.87e-0524453MM15090
PathwayWP_TRANSLATION_FACTORS

EIF4A2 EIF3E PABPC1

5.36e-0450453M39423
PathwayREACTOME_EUKARYOTIC_TRANSLATION_INITIATION

PABPC3 EIF4A2 EIF3E PABPC1

6.24e-04123454MM15415
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

LIG3 POLQ

6.44e-0412452M27569
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

LIG3 POLQ

6.44e-0412452MM15282
PathwayREACTOME_Z_DECAY_DEGRADATION_OF_MATERNAL_MRNAS_BY_ZYGOTICALLY_EXPRESSED_FACTORS

EIF4A2 PABPC1

6.44e-0412452M48027
PathwayREACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY

EIF4A2 PABPC1 EXOSC2

7.49e-0456453M839
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

EIF4A2 EIF3E PABPC1

9.16e-0460453M721
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY

PRKD3 PRKD2

1.02e-0315452M47816
PathwayWP_CORI_CYCLE

PGK1 PGK2

1.31e-0317452M39604
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EPHA1 EPHA7

1.48e-0318452MM15023
Pubmed

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.

PABPC3 PABPC4 PABPC1

3.54e-09354321940797
Pubmed

HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.

PABPC3 PABPC4 PABPC1

3.53e-08554319956697
Pubmed

MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.

PABPC3 PABPC4 PABPC1

3.53e-08554333744966
Pubmed

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.

PABPC3 PABPC4 PABPC1

7.05e-08654310358005
Pubmed

Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.

PABPC3 PABPC4 PABPC1

1.23e-07754310543404
Pubmed

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.

PABPC4 MTREX PABPC1

4.21e-071054327871484
Pubmed

Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.

EIF4A2 PABPC4 EIF3E PABPC1

1.04e-064954424248602
Pubmed

Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.

PGK1 PGK2

2.37e-0625429023984
Pubmed

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

PABPC3 PABPC1

2.37e-06254219020299
Pubmed

Opposing growth regulatory roles of protein kinase D isoforms in human keratinocytes.

PRKD3 PRKD2

2.37e-06254225802335
Pubmed

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.

PABPC3 PABPC1

2.37e-06254210534404
Pubmed

Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme.

PGK1 PGK2

2.37e-0625425009693
Pubmed

Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration.

PRKD3 PRKD2

2.37e-06254224840177
Pubmed

The family of mouse phosphoglycerate kinase genes and pseudogenes.

PGK1 PGK2

2.37e-0625422829366
Pubmed

Characterization of phosphoglycerate kinase from human spermatozoa.

PGK1 PGK2

2.37e-0625421278465
Pubmed

The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.

PABPC3 PABPC1

2.37e-0625429732454
Pubmed

Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment.

PRKD3 PRKD2

2.37e-06254230841931
Pubmed

Protein kinases D2 and D3 are novel growth regulators in HCC1806 triple-negative breast cancer cells.

PRKD3 PRKD2

2.37e-06254223393329
Pubmed

Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse.

PGK1 PGK2

2.37e-0625428662942
Pubmed

Protein kinase D3 conditional knockout impairs osteoclast formation and increases trabecular bone volume in male mice.

PRKD3 PRKD2

2.37e-06254237044359
Pubmed

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.

PGK1 PGK2

2.37e-0625423453121
Pubmed

Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.

PABPC3 PABPC1

2.37e-06254226971890
Pubmed

A factor stimulating transcription of the testis-specific Pgk-2 gene recognizes a sequence similar to the binding site for a transcription inhibitor of the somatic-type Pgk-1 gene.

PGK1 PGK2

2.37e-0625428441629
Pubmed

Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.

PABPC3 PABPC1

2.37e-0625421630930
Pubmed

Transcription switch of two phosphoglycerate kinase genes during spermatogenesis as determined with mouse testis sections in situ.

PGK1 PGK2

2.37e-0625422298243
Pubmed

Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

PABPC3 PABPC1

2.37e-0625427893484
Pubmed

Selective activation of testis-specific genes in cultured rat spermatogenic cells.

PGK1 PGK2

2.37e-0625422166582
Pubmed

Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.

PABPC3 PABPC1

2.37e-06254210954604
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

LIG3 MYL1 PABPC3 EIF4A2 PABPC4 EIF3E PABPC1 PGK1 PGK2

5.76e-0684754935235311
Pubmed

Expression profile of Eph receptors and ephrin ligands in human skin and downregulation of EphA1 in nonmelanoma skin cancer.

EPHA1 EPHA7

7.09e-06354216862074
Pubmed

Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.

PABPC3 PABPC1

7.09e-06354226134869
Pubmed

Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.

PRKD3 PRKD2

7.09e-06354226253275
Pubmed

Expression of the protein kinase D (PKD) family during mouse embryogenesis.

PRKD3 PRKD2

7.09e-06354216377259
Pubmed

Human testis expresses a specific poly(A)-binding protein.

PABPC3 PABPC1

7.09e-06354211328870
Pubmed

Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.

PABPC3 PABPC1

7.09e-06354228635594
Pubmed

Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.

PABPC3 PABPC1

7.09e-06354225034140
Pubmed

The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs.

PABPC3 PABPC1

7.09e-06354210076007
Pubmed

Epab is dispensable for mouse spermatogenesis and male fertility.

PABPC3 PABPC1

7.09e-06354224599567
Pubmed

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene.

PGK1 PGK2

7.09e-0635421380672
Pubmed

A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.

PRKD3 PRKD2

7.09e-06354227662904
Pubmed

Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.

PABPC3 PABPC1

7.09e-06354225370180
Pubmed

Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.

PRKD3 PRKD2

7.09e-06354232747433
Pubmed

Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.

PRKD3 PRKD2

7.09e-06354226426580
Pubmed

Epab and Pabpc1 are differentially expressed during male germ cell development.

PABPC3 PABPC1

7.09e-06354222814100
Pubmed

Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.

PABPC3 PABPC1

7.09e-06354229578408
Pubmed

Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells.

PABPC3 PABPC1

7.09e-06354228611064
Pubmed

SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.

PABPC3 PABPC1

7.09e-06354228756945
Pubmed

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

PABPC3 PABPC1

7.09e-06354226843391
Pubmed

A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.

PABPC3 PABPC1

7.09e-06354237665675
Pubmed

Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.

PABPC3 PABPC1

7.09e-06354229701755
Pubmed

De novo variants in the PABP domain of PABPC1 lead to developmental delay.

PABPC3 PABPC1

7.09e-06354235511136
Pubmed

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.

PRKD3 PRKD2

7.09e-06354238419169
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

COL6A3 PABPC3 PABPC4 DNAH8 PABPC1

1.09e-0518754526460568
Pubmed

UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.

PABPC3 PABPC1

1.42e-05454215314026
Pubmed

Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.

PABPC3 PABPC1

1.42e-05454216804161
Pubmed

Stress granules inhibit apoptosis by reducing reactive oxygen species production.

PABPC3 PABPC1

1.42e-05454223230274
Pubmed

Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.

PRKD3 PRKD2

1.42e-05454227670070
Pubmed

Evolution of complexity in the zebrafish synapse proteome.

PABPC3 PABPC1

1.42e-05454228252024
Pubmed

Transthyretin Upregulates Long Non-Coding RNA MEG3 by Affecting PABPC1 in Diabetic Retinopathy.

PABPC3 PABPC1

1.42e-05454231847264
Pubmed

Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.

PRKD3 PRKD2

1.42e-05454214743217
Pubmed

RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.

PABPC3 PABPC1

1.42e-0545429883581
Pubmed

An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.

PABPC3 PABPC1

1.42e-05454215630085
Pubmed

Dach2-Hdac9 signaling regulates reinnervation of muscle endplates.

HDAC9 DACH2

1.42e-05454226483211
Pubmed

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PABPC3 PABPC1

1.42e-05454224129315
Pubmed

cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.

PABPC3 PABPC1

1.42e-05454228910620
Pubmed

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.

PABPC3 PABPC1

1.42e-05454218490513
Pubmed

ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.

PABPC3 PABPC1

1.42e-05454222956915
Pubmed

Functional cloning of genes that suppress oxidative stress-induced cell death: TCTP prevents hydrogen peroxide-induced cell death.

PABPC3 PABPC1

1.42e-05454219328788
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

LIG3 PABPC4 MTREX PABPC1 EXOSC2 PGK1

1.68e-0534954625665578
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

DCAKD GORASP1 PABPC4 EIF3E MTREX PABPC1 EXOSC2 MOCOS

2.03e-0575454833060197
Pubmed

Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.

PABPC3 PABPC1

2.36e-05554226492470
Pubmed

Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.

HDAC9 PRKD2

2.36e-05554215623513
Pubmed

Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma.

EPHA1 EPHA7

2.36e-05554219949912
Pubmed

Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library.

PABPC3 PABPC1

2.36e-0555421701491
Pubmed

NVL2, a nucleolar AAA-ATPase, is associated with the nuclear exosome and is involved in pre-rRNA processing.

MTREX EXOSC2

2.36e-05554226166824
Pubmed

AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.

PABPC3 PABPC1

2.36e-05554224648398
Pubmed

Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.

PABPC3 PABPC1

2.36e-05554229590218
Pubmed

Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.

PABPC3 PABPC1

2.36e-05554228653618
Pubmed

Protein kinase D regulates RhoA activity via rhotekin phosphorylation.

PRKD3 PRKD2

2.36e-05554222228765
Pubmed

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility.

PGK1 PGK2

3.54e-05654222654668
Pubmed

Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.

PABPC3 PABPC1

3.54e-05654217927953
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

OPN1LW PGK1

3.54e-0565428872469
Pubmed

C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.

MTREX EXOSC2

3.54e-05654217412707
Pubmed

Embryonic poly(A)-binding proteinĀ is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.

PABPC3 PABPC1

3.54e-05654230302808
Pubmed

Translation of insulin granule proteins are regulated by PDI and PABP.

PABPC3 PABPC1

3.54e-05654232248978
Pubmed

Lsh, an epigenetic guardian of repetitive elements.

PGK1 PGK2

4.94e-05754215448183
Pubmed

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.

PABPC3 PABPC1

4.94e-05754234143182
Pubmed

Genetic imbalances in preleukemic thymuses.

PABPC3 PABPC1

4.94e-05754211322760
Pubmed

NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.

PABPC3 PABPC1

4.94e-05754234784943
Pubmed

SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation.

EIF4A2 PABPC4 PABPC1 PGK1

5.10e-0513054432905556
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

PABPC3 PABPC4 EIF3E MTREX PGK1

6.52e-0527254525315684
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ANK2 FAM161A PABPC3 EIF4A2 PABPC4 POLQ DNAH8 PABPC1 PGK1 PGK2

6.58e-051442541035575683
Pubmed

Localization of the mdx mutation within the mouse dystrophin gene.

OPN1LW PGK1

6.59e-0585422903046
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

PABPC3 PABPC1

6.59e-05854222621333
Pubmed

Near-Infrared Luciferase Complementation Assay with Enhanced Bioluminescence for Studying Protein-Protein Interactions and Drug Evaluation Under Physiological Conditions.

PABPC4 PABPC1

6.59e-05854236135776
Pubmed

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.

PABPC3 PABPC1

6.59e-05854221262862
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

EIF4A2 EIF3E PABPC1 PGK1

7.19e-0514254430809309
Pubmed

Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region.

EIF4A2 EIF3E PABPC1

7.84e-055354312588972
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

MYL1 EIF4A2 PABPC4 PABPC1 CSTF2T

7.86e-0528354528533407
Pubmed

Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.

OPN1LW PGK1

8.46e-0595421973136
Cytoband11q25

THYN1 SNX19

4.33e-042654211q25
CytobandEnsembl 112 genes in cytogenetic band chr11q25

THYN1 SNX19

6.18e-0431542chr11q25
Cytoband4q13.3

SULT1B1 UGT2A2

1.13e-03425424q13.3
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA1 EPHA7

4.49e-04144121095
GeneFamilyRNA binding motif containing

PABPC3 PABPC4 PABPC1 CSTF2T

1.35e-03213414725
GeneFamilyTransient receptor potential cation channels

TRPM5 TRPM2

1.83e-0328412249
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRPM5 PABPC1 PGK2 EPHA1

2.74e-06805440d02b242164d27f38f70ed77b106612fc7a3abca
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRPM5 PABPC1 PGK2 EPHA1

2.74e-0680544313344cf7309bc17ca131b92a91b24489df577e2
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Tmem2_(Tmem2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRPM5 PABPC1 PGK2 EPHA1

2.74e-0680544b95e4456adb7f7d42825351f010376c10bb35380
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND01-03-samps / Age Group, Lineage, Cell class and subclass

IGSF10 TRPM5 POLQ IQCG

2.31e-05137544a69976938d4e89315ec0be3a332b91ddf3799d65
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TBXAS1 COL6A3 SULT1B1

5.33e-056054348adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TBXAS1 COL6A3 SULT1B1

5.33e-0560543a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

AMT ANK2 POLQ FBXO47

5.49e-051715440eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCellBL-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRKD3 HDAC9 GGA2 DNAH8

7.61e-0518654427d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYL1 IDO1 PDCL2 MOCOS

8.10e-05189544e97c64609b1f8158d750edb869df56e5bd10538b
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 COL6A3 NOX4 EPHA1

8.43e-05191544cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 COL6A3 NOX4 EPHA1

8.60e-05192544ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 COL6A3 NOX4 EPHA1

8.60e-051925442d3790bd80a7f214b37094121a2a86ff16362569
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

PABPC4 EIF3E PABPC1 EPHA1

8.78e-05193544627d345baf1940218c61907305705298e473dbab
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKD3 IGSF10 GGA2 PABPC1

9.13e-05195544cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellproximal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TBXAS1 IDO1 PABPC3 TRPM2

9.13e-051955448592d0332bc82a91e173680cfd1afc5ee189b289
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGSF10 COL6A3 ANK2 NOX4

9.13e-05195544f54bc4454270ff06e85596f98199372b50d0179f
ToppCellproximal-Hematologic-IGSF21+_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TBXAS1 IDO1 PABPC3 TRPM2

9.13e-05195544c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 HDAC9 IDO1 TRPM2

9.13e-05195544247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 COL6A3 EIF4A2 MTREX

9.13e-05195544c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellproximal-Hematologic-IGSF21+_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TBXAS1 IDO1 PABPC3 TRPM2

9.13e-05195544ae9d61011e95f7840cbb154738c79745fd29943e
ToppCellBronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 HDAC9 IDO1 POLQ

9.32e-0519654453d1f9e9f009d1417a19ca6f9a83ecdf7776ef88
ToppCellmetastatic_Lymph_Node-T/NK_cells-Naive_CD4+_T|T/NK_cells / Location, Cell class and cell subclass

EIF4A2 PABPC4 EIF3E PABPC1

9.32e-051965449cc517373ce4374140ab153edc87ec5517ee1f63
ToppCellproximal-3-Hematologic-Plasma|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NXPE4 PABPC4 ZNF215 MOCOS

9.32e-051965441ca453582b5db8f1ea20a846e698c54edf0a1f25
ToppCellproximal-Hematologic-Plasma-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NXPE4 PABPC4 ZNF215 MOCOS

9.32e-05196544f6e842b18765c2d923706cabb5d17efeff1da5aa
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKD3 PABPC4 DNAH8 TRIM44

9.32e-051965440175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 HDAC9 ZNF215 DNAH8

9.32e-05196544fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCellproximal-Hematologic-Plasma|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NXPE4 PABPC4 ZNF215 MOCOS

9.32e-05196544621f112a71f3d82fd75da8addfb16d86f590fe33
ToppCellnormal_Pleural_Fluid-T/NK_cells-Naive_CD4+_T|T/NK_cells / Location, Cell class and cell subclass

EIF4A2 PABPC4 EIF3E PABPC1

9.32e-051965445958caed4172ca478a6d9112d50af9070c850b96
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 HDAC9 TRPM2 POLQ

9.50e-051975440a404b4494a2246d5a92299235056f0fda4d2b48
ToppCellMesenchymal_cells-Arteriolar_fibro.|Mesenchymal_cells / Lineage and Cell class

IGSF10 COL6A3 ANK2 NOX4

9.50e-05197544cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 HDAC9 TRPM2 POLQ

9.69e-05198544732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell(06)_OLFM4+|World / shred by cell type by condition

TBXAS1 PDE9A IDO1 RAB27B

9.88e-05199544c773b9180dbfec9c19d4098dd43332e6f6050372
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HDAC9 GGA2 ANK2 DNAH8

1.01e-04200544fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellmild-B_intermediate|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HDAC9 GGA2 ANK2 DNAH8

1.01e-042005448e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 HDAC9 IDO1 TRPM2

1.01e-0420054441a206350eff2a196ccc1a36a9636a87c74f6962
ToppCellSepsis-URO-Myeloid-cDC2|URO / Disease, condition lineage and cell class

HDAC9 IDO1 EIF3E PABPC1

1.01e-042005444f696dc68a8ceec9a6e6293c6f6f878b321b0b6d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TBXAS1 COL6A3 PABPC1

1.08e-0476543efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TBXAS1 COL6A3 PABPC1

1.08e-0476543254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACH2 FAM161A FBXO47

2.03e-049454300b932421d77f0fd8d6ffe439c992ebc95ad7c94
ToppCell367C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF215 POLQ EPHA1

2.22e-0497543a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell367C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF215 POLQ EPHA1

2.22e-049754312cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRPM5 PGK2 EPHA1

3.22e-04110543bede775886b45cce4aa229baead0e800b5be25a8
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HDAC9 AMT DACH2

4.47e-04123543e0130010aa406d4e9d8f16ad32858c382277eeb2
ToppCellBronchial_Brush-Epithelial-Ciliated_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ANK2 PDE9A IDO1

5.49e-04132543780a391924f776dc6fbe44ddcf4ae0583a1e2157
ToppCellBronchial_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ANK2 PDE9A IDO1

5.86e-04135543366a417f9ef7c0d86e9f262d97bf788f478315ee
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-4|TCGA-Kidney / Sample_Type by Project: Shred V9

NOX4 DNAH8 MOCOS

6.12e-04137543758aa466a01265ed67b94f1578b4099956506271
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 PABPC1 HYDIN

6.38e-0413954327dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 PABPC1 HYDIN

6.38e-041395432a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKD3 HDAC9 PDE9A

6.38e-041395439e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMT SULT1B1 MYL1

6.38e-04139543e363c69b58cff8571ca75b91a3d052f9cbccac27
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMT SULT1B1 MYL1

6.51e-0414054339083c3e288d1878fdc4c798e600fb156daff8a9
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMT SULT1B1 MYL1

6.51e-0414054306e14a375ea85175c809ff5a0ea16e865ccb4ad5
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

LIG3 ANK2 IQCG

6.79e-041425430e0f8bb956ff89dc98e8fa56f8acac33e01a26dd
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 NOX4 CSTF2T

7.21e-0414554347a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

7.50e-041475439bc4185920b2b0f1fd5c6e2ec5583b9cd49c2efd
ToppCellClub_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

IGSF10 MTREX EPHA7

7.50e-041475439211242a8e40d50414d310940616eccce299a7f8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

7.50e-041475439b0f87a6dd5224c2b06deafeae04a1b04e53eb75
ToppCellSerous|World / shred by cell class for turbinate

DACH2 NXPE4 EPHA7

7.95e-041505436a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TBXAS1 HDAC9 IDO1

8.26e-041525430769857f25da2e6169420818e61d65e33b7277b1
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBXAS1 DNAH8 RAB27B

8.26e-04152543aff7d1127ef72be489477611c4decc53cc7632e3
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBXAS1 DNAH8 RAB27B

8.26e-041525430a99c91165e4d82fb8825fbdf3071c9a5445669d
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 ANK2 TRPM2

8.26e-04152543b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCellRV-17._Lymphocyte|RV / Chamber and Cluster_Paper

TBXAS1 TRPM2 RAB27B

8.42e-04153543e1ea621184014415870e00d511386b8cc3e0833b
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ANK2 DACH2

8.58e-04154543dd3d34f065820e706515a13619f19a5b12734c8e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

8.58e-04154543c6f1a0806d492b1f01cded2daffaf3f13422deb6
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ANK2 DACH2

8.58e-041545434bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellDendritic_Cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

HDAC9 PABPC4 PABPC1

8.58e-0415454365013f696da623d37f1e3447a294dfb3c31ae93b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

8.58e-04154543665885d8aca168513ab7a65f70d52181c821eb78
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

8.58e-041545433c64111e2ca1bb04ddd1ecb19938a307778ff7eb
ToppCellRV-17._Lymphocyte|World / Chamber and Cluster_Paper

TBXAS1 TRPM2 RAB27B

8.74e-04155543189276a3b400b2202e6681e23732e6452bfe704e
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 SYCP2L IDO1

8.91e-04156543841d653d74c4de41d2f9a114f6ccb92d6a1ebc24
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYCP2L AMT RAB27B

8.91e-0415654317c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HDAC9 SYCP2L IDO1

8.91e-04156543a917b3e799a7b2a3c7f36af61f2b69292c0fb5c0
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|343B / Donor, Lineage, Cell class and subclass (all cells)

PRKD3 DCAKD AMT

9.07e-041575430362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE4 RCVRN HYDIN

9.24e-041585439fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE4 RCVRN HYDIN

9.24e-041585430edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

PABPC3 EIF4A2 EPHA1

9.58e-04160543f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 TTLL11 RAB27B

9.76e-0416154352556b89808e551540f33a13f57417a6696c2438
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HDAC9 COL6A3 MYL1

9.76e-04161543be77e99faf653480c166305df3a4e93db76f0dcb
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 TTLL11 RAB27B

9.76e-0416154354f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

HDAC9 IDO1 HYDIN

9.76e-041615432f068ee643de2f647c289779a6624265ab9a749b
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 TTLL11 RAB27B

9.76e-04161543242891be849a4398fe8bea44875ae1ba57950944
ToppCellfacs-SCAT-Fat-24m-Epithelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

1.01e-031635439fd2e495efb6c447cdc52efdb3b695cb2fa8b914
ToppCellASK428-Immune-Mast_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SYCP2L EIF3E RAB27B

1.01e-03163543569ca0e8ce307f258910b0c75c498009a9651e6e
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 TRPM2 IQCG

1.01e-031635437a04192710f55acf5a4681d5f09942358fdb02ff
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 NXPE4 TRPM2

1.01e-031635438dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCellfacs-SCAT-Fat-24m-Epithelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

1.01e-03163543ade2f59bca0ab0c4856202f980464f3287bddd24
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 NXPE4 TRPM2

1.01e-03163543fd243ca223079033be480a24817a399f281fa4d4
ToppCellfacs-SCAT-Fat-24m-Epithelial-epithelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCL2 PABPC1 PGK2

1.01e-03163543aaf5d96bab1957c7bde84c741c7f2fb86ef41e8b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOX4 HYDIN EPHA7

1.03e-031645431cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NXPE4 PABPC4 ZNF215

1.03e-031645432d65f025f921a5327bfd8d260815baaed00ef3fa
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBXAS1 HDAC9 IDO1

1.05e-03165543d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

FAM161A ZNF215 IQCG

1.05e-03165543ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

LIG3 AMT GORASP1

1.07e-03166543c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF10 COL6A3 TTLL11

1.07e-0316654349103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL1 PDCL2 PGK2

1.07e-03166543c71ad3fc6a14507609d17756431d3deff9fda418
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBXAS1 HDAC9 TRPM2

1.08e-031675431bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 TRPM2 IQCG

1.08e-03167543528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

SYCP2L IDO1 NOX4

1.08e-031675435af9127bae05768a5164d5708a4ad37edca99324
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 TRPM2 IQCG

1.08e-03167543a82e85caf79395baa48380786d9df32a86dfd1ce
ComputationalGenes in the cancer module 115.

EIF4A2 EIF3E PABPC1

1.12e-0427383MODULE_115
ComputationalTranslation factors.

EIF4A2 EIF3E PABPC1

2.92e-0437383MODULE_149
Drug5-fluorotryptophan

IDO1 MTREX PGK1 PGK2

3.44e-0725544CID000009577
Drug4-Arsono-2-hydroxybutanoic acid

PGK1 PGK2

5.52e-062542CID000135804
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

TBXAS1 AMT SULT1B1 ANK2 EXOSC2 MOCOS

6.14e-061925462699_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

DCAKD LIG3 NDST1 GGA2 TRPM2 CSTF2T

7.11e-061975464461_DN
DrugVitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A

TBXAS1 LIG3 GGA2 ZNF215 SNX19 CSTF2T

7.53e-061995464534_DN
DrugDirian

PGK1 PGK2

1.65e-053542CID003034337
DrugAC1NDNJY

PGK1 PGK2

1.65e-053542CID004578722
DrugAC1O5U9L

PGK1 PGK2

1.65e-053542CID006440811
Drugrepin

PGK1 PGK2

3.30e-054542CID000091567
Drugilmofosine

PRKD3 PRKD2 MOCOS

3.54e-0527543CID000055008
Drugclorsulon

PGK1 PGK2

5.50e-055542CID000043231
Druganthranilic acid

IDO1 MTREX PABPC1 PGK1

5.94e-0589544CID000000227
DrugBq123

PRKD3 TBXAS1 PRKD2 MOCOS

7.67e-0595544CID000443289
DrugY-27632

PRKD3 PRKD2 COL6A3 MYL1 GORASP1 NOX4 EPHA1

8.21e-05444547CID000005711
DrugKS24

PABPC3 PABPC1

8.23e-056542CID000099135
DrugCDVpp

PGK1 PGK2

8.23e-056542CID000501655
Drugesperamicin A1

PGK1 PGK2

8.23e-056542CID006435576
Drugiso-H7

PRKD3 PRKD2 MYL1

9.26e-0537543CID000001352
DrugFim 1

PRKD3 PRKD2 MOCOS

9.26e-0537543CID000132906
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; HL60; HG-U133A

PRKD3 LIG3 NDST1 GGA2 EXOSC2

9.61e-051945451416_DN
DrugAlfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A

LIG3 NDST1 ANK2 EXOSC2 EPHA1

9.85e-051955455451_UP
DrugGliclazide [21187-98-4]; Down 200; 12.4uM; PC3; HT_HG-U133A

DCAKD LIG3 GGA2 ZNF215 RAB27B

9.85e-051955455089_DN
DrugBisoprolol fumarate; Down 200; 9uM; PC3; HT_HG-U133A

TBXAS1 GGA2 RAB27B EPHA1 EPHA7

1.01e-041965456748_DN
DrugE)-4-hydroxytamoxifen

PRKD3 HDAC9 PRKD2 GGA2 NOX4

1.03e-04197545CID000063062
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A

TBXAS1 SULT1B1 GGA2 ZNF215 CSTF2T

1.03e-041975456663_DN
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A

LIG3 NDST1 SULT1B1 CSTF2T MOCOS

1.03e-041975451609_UP
DrugLisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; HL60; HG-U133A

NDST1 GGA2 TRPM2 WASHC3 EXOSC2

1.08e-041995452046_DN
Drug12-deoxyphorbol 13-isobutyrate

PRKD3 PRKD2 MYL1

1.08e-0439543CID000107855
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; PC3; HT_HG-U133A

PRKD2 LIG3 AMT GGA2 IQCG

1.11e-042005454489_DN
DrugSC-11927

PGK1 PGK2

1.15e-047542CID003034422
Drugethyl octanoate

PGK1 PGK2

1.15e-047542CID000007799
DrugAC1L18QD

PRKD3 TBXAS1 PRKD2 COL6A3 MYL1 OPN1LW

1.17e-04325546CID000000213
DrugSC-9

PRKD3 HDAC9 PRKD2

1.46e-0443543CID000124172
Drugcholesterol sulfate

PRKD3 PRKD2 PGK1 PGK2

1.50e-04113544CID000065076
Drugheptenoic acid

TBXAS1 HDAC9

1.53e-048542CID000029373
Drugethyl decanoate

PGK1 PGK2

1.53e-048542CID000008048
Drugadenine

TRPM5 PABPC3 NOX4 POLQ PABPC1 PGK1 PGK2

1.93e-04510547CID000000190
DrugAdenosine-3'-5'-Diphosphate

NDST1 SULT1B1

1.97e-049542DB01812
Drugphenethyl acetate

PGK1 PGK2

1.97e-049542CID000007654
DrugAC1MI08J

PGK1 PGK2

1.97e-049542CID003035924
DrugRh(H2O)4ATP

PGK1 PGK2

1.97e-049542CID003082848
Drugchloroethylguanine

PGK1 PGK2

1.97e-049542CID000161383
Drug2-methoxy-5-nitrotropone

PGK1 PGK2

1.97e-049542CID000084563
Drugpotassium hydride

PABPC4 NOX4 PABPC1 EXOSC2

2.42e-04128544CID000082127
Drug1 mN-9

PGK1 PGK2

2.45e-0410542CID000122108
DrugACVDP

PGK1 PGK2

2.45e-0410542CID000501523
Drug25-azacoprostane

PGK1 PGK2

2.45e-0410542CID000162243
Drugdiphenyline

HDAC9 NOX4

2.45e-0410542CID000010292
Drug1i32

COL6A3 PABPC3 EIF4A2 PABPC1

2.50e-04129544CID000446186
DiseaseIschemic stroke

HDAC9 COL6A3 ANK2 PDE9A EIF4A2

3.15e-04324545HP_0002140
Diseasephosphatidylcholine 36:3 measurement

PABPC1 IQCG

3.40e-0415542EFO_0010381
Diseasecoffee consumption measurement

PRKD2 PABPC4 EIF3E HYDIN

3.48e-04182544EFO_0006781
Diseasedescending aortic diameter

HDAC9 COL6A3 NOX4

5.70e-0488543EFO_0021788
Diseasepulse pressure measurement

PRKD3 TBXAS1 HDAC9 LIG3 COL6A3 ANK2 NOX4 SNX19 HYDIN

8.80e-041392549EFO_0005763
Diseasesevere acute respiratory syndrome, COVID-19

COL6A3 DACH2 TRPM2 FBXO47 EPHA7

1.34e-03447545EFO_0000694, MONDO_0100096
Diseaseblood pressure, chronic obstructive pulmonary disease

HDAC9 PABPC4

1.57e-0332542EFO_0000341, EFO_0004325
Diseaseresponse to cytosine arabinoside

ZNF215 EPHA7

1.88e-0335542EFO_0005655
Diseasestroke

HDAC9 ANK2 EPHA7

2.35e-03144543EFO_0000712
Diseasecholesteryl ester 20:5 measurement

SYCP2L EPHA7

2.96e-0344542EFO_0010349
Diseasecandidiasis (implicated_via_orthology)

PRKD3 PRKD2

2.96e-0344542DOID:1508 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VVTKRKPIMIITEFM

EPHA1

691

P21709
ERMEEVPVQIPIMKS

DACH2

411

Q96NX9
MQDLVFKKPTRQTIM

IQCG

146

Q9H095
KTMIKKIMRQIQEEP

MROH7

456

Q68CQ1
GKRVIMRVDFNVPMK

PGK2

16

P07205
MRVDFNVPMKKNQIT

PGK2

21

P07205
IMKRMEQCVEKTQIP

RAB27B

181

O00194
KAEKEVTRMVVVMIF

OPN1LW

261

P04000
TMNFDVIKGKPVRIM

PABPC1

71

P11940
RFTPEEEMFKMVTKI

ANK2

2581

Q01484
TMNFDVIKGKPIRIM

PABPC4

71

Q13310
IPTVFKAMQMQERDT

IDO1

181

P14902
RLQKEAMVKPFEKMT

PDCL2

36

Q8N4E4
ETVTKLFPMVEEIML

PDE9A

526

O76083
ENLKIQFRTVAMMVP

DNAH8

1961

Q96JB1
RKMTVFIDDINMPVI

DNAH8

2516

Q96JB1
LRTEPAKVMDMVQKF

NDST1

781

P52848
MFETPEKVFVVMEKL

PRKD2

616

Q9BZL6
MFETPERVFVVMEKL

PRKD3

641

O94806
DIMFQVAVPKSMRVK

GGA2

531

Q9UJY4
RIMVIKAKGMEPIEV

MOCOS

646

Q96EN8
KKIEFEQFLPMMQAI

MYL1

106

P05976
GKRVVMRVDFNVPMK

PGK1

16

P00558
MVEIPNRIMFSEMKR

LIG3

621

P49916
ILKPEIMEEIVMETR

EXOSC2

271

Q13868
VTRGKPVMIVIEFME

EPHA7

701

Q15375
PVKLEVFNMKTMRVR

GORASP1

66

Q9BQQ3
VMEIRMVKENFKARP

NOX4

321

Q9NPH5
TMNFDVIKGKPVRIM

PABPC3

71

Q9H361
PITVRTMIKDVNVKM

IGSF10

921

Q6WRI0
QDPKVVFPQRKMDMK

HYDIN

2796

Q4G0P3
VFPQRKMDMKTNEVI

HYDIN

2801

Q4G0P3
ITHPEIRKEMMKETF

DCAKD

86

Q8WVC6
SMKLVREFEPMLQVK

POLQ

306

O75417
KPMVKMSREVQVFEI

COL6A3

2986

P12111
IVKMFEDPETTRQMQ

EIF3E

91

P60228
TMPTDVLEVTKKFMR

EIF4A2

216

Q14240
MMQKVCKVFSTPVER

FBXO47

376

Q5MNV8
QVVMRIMDPEIALKI

CSTF2T

176

Q9H0L4
RMMMPVVDPVVREKQ

HDAC9

31

Q9UKV0
RRKQQMAVVSKMPFV

AMT

381

P48728
PFQMMIREQKKKEES

FAM161A

241

Q3B820
SDPKVTRDQMKMFIQ

TRIM44

246

Q96DX7
PDTMVIIKTENIREM

NXPE4

466

Q6UWF7
EVLEIVMAIFKMITP

RCVRN

121

P35243
KRGFITEKVPMLEMT

SULT1B1

71

O43704
MFIVISEPDMIKQVL

TBXAS1

86

P24557
QVNKFPGMTEMVRKI

TTLL11

271

Q8NHH1
PKIIVVERMMKDVFF

TRPM5

861

Q9NZQ8
PSNVFKIVKMIMERN

MTREX

371

P42285
KIVKMIMERNFQPVI

MTREX

376

P42285
GPKIIIVKRMMKDVF

TRPM2

921

O94759
KPMIISYKEVMKIEI

SYCP2L

371

Q5T4T6
FVKKPFMVSRIDKMV

SNX19

666

Q92543
VDVQFVRMMKRFIPL

THYN1

161

Q9P016
IMEKEIPRKTIFDMK

ZNF215

226

Q9UL58
KMVQVGVPVMAIRNK

WASHC3

141

Q9Y3C0
MVSIRDFTMPKKFVQ

UGT2A2

1

P0DTE5