Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetyl-L-aspartate-L-glutamate ligase activity	RIMKLB RIMKLA	6.14e-06	2	50	2	GO:0072590
GeneOntologyMolecularFunction	olfactory receptor activity	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	1.07e-05	431	50	8	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8I2 OR5T1 OR10K2 OR10T2	2.87e-04	127	50	4	GO:0005549
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	3.06e-04	884	50	9	GO:0004930
GeneOntologyMolecularFunction	ligase activity, forming carbon-nitrogen bonds	RIMKLB RIMKLA PFAS	3.17e-04	53	50	3	GO:0016879
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A11 SLC44A1 TIMM23B SLC22A15 SLC35F6 SFXN2 TIMM23 SLC4A5 CHRNG SLC16A10	5.88e-04	1180	50	10	GO:0022857
GeneOntologyMolecularFunction	ubiquitin-protein transferase activator activity	BMI1 PCGF2	9.16e-04	18	50	2	GO:0097027
GeneOntologyMolecularFunction	transporter activity	SLC6A11 SLC44A1 TIMM23B SLC22A15 SLC35F6 SFXN2 TIMM23 SLC4A5 CHRNG SLC16A10	1.16e-03	1289	50	10	GO:0005215
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC44A1 SLC22A15 SLC16A10	1.18e-03	83	50	3	GO:0015101
GeneOntologyMolecularFunction	phosphotransferase activity, for other substituted phosphate groups	DPAGT1 PIGO	1.37e-03	22	50	2	GO:0016780
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1 CHRNG	1.67e-03	1353	50	10	GO:0004888
GeneOntologyMolecularFunction	protein transmembrane transporter activity	TIMM23B TIMM23	2.23e-03	28	50	2	GO:0008320
GeneOntologyMolecularFunction	macromolecule transmembrane transporter activity	TIMM23B TIMM23	3.28e-03	34	50	2	GO:0022884
GeneOntologyMolecularFunction	ubiquitin-protein transferase regulator activity	BMI1 PCGF2	3.47e-03	35	50	2	GO:0055106
GeneOntologyMolecularFunction	protein transporter activity	TIMM23B TIMM23	4.96e-03	42	50	2	GO:0140318
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A11 SLC44A1 SLC4A5 SLC16A10	6.38e-03	296	50	4	GO:0015291
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	8.62e-06	432	50	8	GO:0050911
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8I2 OR5T1 EYS OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	9.51e-06	582	50	9	GO:0050906
GeneOntologyBiologicalProcess	sensory perception of smell	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	1.47e-05	465	50	8	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	1.99e-05	485	50	8	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	3.45e-05	524	50	8	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	4.68e-05	547	50	8	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus	OR8I2 OR5T1 EYS OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	5.19e-05	722	50	9	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR8I2 OR5T1 EYS OR10K2 OR7A17 OR52M1 CLRN1 OR7A10 OR10T2 OR2AE1	2.12e-04	1072	50	10	GO:0007600
GeneOntologyBiologicalProcess	import into the mitochondrion	TIMM23B SFXN2 TIMM23	3.05e-04	54	50	3	GO:0170036
GeneOntologyCellularComponent	migrasome	TIMM23B TIMM23	2.08e-04	9	51	2	GO:0140494
GeneOntologyCellularComponent	TIM23 mitochondrial import inner membrane translocase complex	TIMM23B TIMM23	6.85e-04	16	51	2	GO:0005744
GeneOntologyCellularComponent	PRC1 complex	BMI1 PCGF2	9.72e-04	19	51	2	GO:0035102
Domain	-	RIMKLB SYN3 RIMKLA	4.47e-06	13	48	3	3.40.50.20
Domain	PreATP-grasp_dom	RIMKLB SYN3 RIMKLA	5.68e-06	14	48	3	IPR016185
Domain	ATP-grasp_RimK-type	RIMKLB RIMKLA	6.47e-06	2	48	2	IPR013651
Domain	RimK	RIMKLB RIMKLA	6.47e-06	2	48	2	PF08443
Domain	RpS6_RimK/Lys_biosynth_LsyX	RIMKLB RIMKLA	6.47e-06	2	48	2	IPR004666
Domain	Olfact_rcpt	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	6.47e-06	393	48	8	IPR000725
Domain	-	RIMKLB SYN3 RIMKLA	7.09e-06	15	48	3	3.30.1490.20
Domain	-	RIMKLB SYN3 RIMKLA	1.27e-05	18	48	3	3.30.470.20
Domain	ATP_grasp_subdomain_1	RIMKLB SYN3 RIMKLA	1.27e-05	18	48	3	IPR013815
Domain	GPCR_Rhodpsn_7TM	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	4.46e-05	670	48	9	IPR017452
Domain	7tm_1	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	4.84e-05	677	48	9	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	5.30e-05	685	48	9	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	5.67e-05	691	48	9	PS50262
Domain	GPCR_Rhodpsn	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 PTGFR OR7A10 OR10T2 OR2AE1	5.73e-05	692	48	9	IPR000276
Domain	ATP_grasp_subdomain_2	RIMKLB SYN3 RIMKLA	6.81e-05	31	48	3	IPR013816
Domain	Tetraspanin	TSPAN8 TSPAN32 TSPAN33	7.50e-05	32	48	3	IPR000301
Domain	Tetraspanin_EC2	TSPAN8 TSPAN32 TSPAN33	7.50e-05	32	48	3	IPR008952
Domain	Tetraspannin	TSPAN8 TSPAN32 TSPAN33	8.23e-05	33	48	3	PF00335
Domain	Tetraspanin/Peripherin	TSPAN8 TSPAN32 TSPAN33	8.23e-05	33	48	3	IPR018499
Domain	ATP-grasp	RIMKLB RIMKLA	5.77e-04	14	48	2	IPR011761
Domain	ATP_GRASP	RIMKLB RIMKLA	5.77e-04	14	48	2	PS50975
Domain	Alkaline_phosphatase_core	ARSH PIGO	2.87e-03	31	48	2	IPR017850
Domain	Alkaline_Pase-like_a/b/a	ARSH PIGO	2.87e-03	31	48	2	IPR017849
Domain	-	ARSH PIGO	2.87e-03	31	48	2	3.40.720.10
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	3.03e-06	389	34	8	M14091
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	5.06e-06	417	34	8	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2 OR2AE1	1.05e-04	636	34	8	M41834
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A11 SLC44A1 SLC22A15 SLC4A5 SLC16A10	2.45e-04	238	34	5	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A11 SLC44A1 SLC22A15 SLC4A5 SLC16A10	3.02e-04	249	34	5	M5988
Pathway	REACTOME_GLUTAMATE_AND_GLUTAMINE_METABOLISM	RIMKLB RIMKLA	5.05e-04	14	34	2	M27851
Pathway	REACTOME_GLUTAMATE_AND_GLUTAMINE_METABOLISM	RIMKLB RIMKLA	5.05e-04	14	34	2	MM15570
Pathway	REACTOME_SUMOYLATION_OF_DNA_METHYLATION_PROTEINS	BMI1 PCGF2	6.63e-04	16	34	2	M27403
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC6A11 SLC44A1 SLC22A15	7.99e-04	76	34	3	MM15072
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC6A11 SLC44A1 SLC22A15	1.07e-03	84	34	3	M27334
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	BMI1 PCGF2	1.64e-03	25	34	2	MM15546
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	BMI1 PCGF2	1.77e-03	26	34	2	M47923
Pathway	WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER	BMI1 CD96	2.05e-03	28	34	2	M42549
Pathway	REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES	SLC6A11 SLC44A1 RIMKLB RIMKLA	2.74e-03	245	34	4	MM15403
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	BMI1 PCGF2	3.02e-03	34	34	2	M27826
Pubmed	Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma.	BMI1 PCGF2	2.11e-06	2	51	2	20717685
Pubmed	Expression and clinicopathological significance of Mel-18 and Bmi-1 mRNA in gastric carcinoma.	BMI1 PCGF2	2.11e-06	2	51	2	21059209
Pubmed	Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis.	BMI1 PCGF2	2.11e-06	2	51	2	17452456
Pubmed	Effect of Tim23 knockdown in vivo on mitochondrial protein import and retrograde signaling to the UPRmt in muscle.	TIMM23B TIMM23	2.11e-06	2	51	2	29949403
Pubmed	Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.	RIMKLB RIMKLA	2.11e-06	2	51	2	20657015
Pubmed	Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells.	BMI1 PCGF2	2.11e-06	2	51	2	17545584
Pubmed	BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.	BMI1 PCGF2	2.11e-06	2	51	2	20170541
Pubmed	Expression of BMI-1 and Mel-18 in breast tissue--a diagnostic marker in patients with breast cancer.	BMI1 PCGF2	2.11e-06	2	51	2	21162745
Pubmed	Hormonal regulation of mitochondrial Tim23 gene expression in the mouse mammary gland.	TIMM23B TIMM23	2.11e-06	2	51	2	11165051
Pubmed	Appearance of new tetraspanin genes during vertebrate evolution.	TSPAN8 TSPAN32 TSPAN33	3.33e-06	20	51	3	18291621
Pubmed	A novel cysteine-rich sequence motif.	BMI1 PCGF2	6.32e-06	3	51	2	1991318
Pubmed	Functional analysis of mouse Polycomb group genes.	BMI1 PCGF2	6.32e-06	3	51	2	9487388
Pubmed	N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate.	RIMKLB RIMKLA	6.32e-06	3	51	2	21454531
Pubmed	A novel zinc finger coiled-coil domain in a family of nuclear proteins.	BMI1 PCGF2	6.32e-06	3	51	2	1412709
Pubmed	NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model.	RIMKLB RIMKLA	6.32e-06	3	51	2	38011891
Pubmed	Regulation of hematopoietic stem cells using protein transduction domain-fused Polycomb.	BMI1 PCGF2	6.32e-06	3	51	2	22634509
Pubmed	Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas.	BMI1 PCGF2	6.32e-06	3	51	2	17145810
Pubmed	Mutant huntingtin does not cross the mitochondrial outer membrane.	TIMM23B TIMM23	6.32e-06	3	51	2	32821928
Pubmed	Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.	TIMM23B TIMM23	6.32e-06	3	51	2	12437925
Pubmed	Development of renal failure in PargParp-1 null and Timm23 hypomorphic mice.	TIMM23B TIMM23	6.32e-06	3	51	2	31326434
Pubmed	Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins.	BMI1 PCGF2	6.32e-06	3	51	2	17151361
Pubmed	Reciprocal expression of Bmi1 and Mel-18 is associated with functioning of primitive hematopoietic cells.	BMI1 PCGF2	6.32e-06	3	51	2	19409954
Pubmed	Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease.	TIMM23B TIMM23	6.32e-06	3	51	2	30405116
Pubmed	NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming.	TIMM23B TIMM23	6.32e-06	3	51	2	37044213
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10	1.04e-05	340	51	6	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10	1.04e-05	340	51	6	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10	1.09e-05	343	51	6	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10	1.15e-05	346	51	6	14611657
Pubmed	Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.	TIMM23B TIMM23	1.26e-05	4	51	2	19111522
Pubmed	Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond.	BMI1 PCGF2	1.26e-05	4	51	2	9153995
Pubmed	Polycomb repressive complex 1 modulates granulosa cell proliferation in early folliculogenesis to support female reproduction.	BMI1 PCGF2	1.26e-05	4	51	2	38389850
Pubmed	Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex.	BMI1 PCGF2	1.26e-05	4	51	2	9009205
Pubmed	The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix.	TIMM23B TIMM23	1.26e-05	4	51	2	10393182
Pubmed	The human olfactory receptor gene family.	OR8I2 OR5T1 OR10K2 OR7A17 OR52M1 OR7A10 OR10T2	1.36e-05	541	51	7	14983052
Pubmed	MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.	BMI1 PCGF2	2.10e-05	5	51	2	27773671
Pubmed	Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF.	BMI1 PCGF2	2.10e-05	5	51	2	14560011
Pubmed	Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.	BMI1 PCGF2	2.10e-05	5	51	2	15589172
Pubmed	A spastic paraplegia mouse model reveals REEP1-dependent ER shaping.	TIMM23B TIMM23	3.15e-05	6	51	2	24051375
Pubmed	Visualizing an olfactory sensory map.	OR7A17 OR7A10	3.15e-05	6	51	2	8929536
Pubmed	Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.	TIMM23B TIMM23	3.15e-05	6	51	2	15282315
Pubmed	Essential Role for Polycomb Group Protein Pcgf6 in Embryonic Stem Cell Maintenance and a Noncanonical Polycomb Repressive Complex 1 (PRC1) Integrity.	BMI1 PCGF2	4.41e-05	7	51	2	28049731
Pubmed	Topology and enzymatic properties of a canonical Polycomb repressive complex 1 isoform.	BMI1 PCGF2	4.41e-05	7	51	2	31093962
Pubmed	BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3.	BMI1 PCGF2	4.41e-05	7	51	2	28780076
Pubmed	Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology.	TIMM23B TIMM23	4.41e-05	7	51	2	21984432
Pubmed	REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements.	BMI1 PCGF2	4.41e-05	7	51	2	21402785
Pubmed	Role of Bax and Bak in mitochondrial morphogenesis.	TIMM23B TIMM23	4.41e-05	7	51	2	17035996
Pubmed	Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.	BMI1 PCGF2	4.41e-05	7	51	2	15964995
Pubmed	BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase.	BMI1 PCGF2	5.87e-05	8	51	2	26151332
Pubmed	Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.	TIMM23B TIMM23	5.87e-05	8	51	2	15044455
Pubmed	Functional redundancy among Polycomb complexes in maintaining the pluripotent state of embryonic stem cells.	BMI1 PCGF2	5.87e-05	8	51	2	35364009
Pubmed	The DNA sequence and biology of human chromosome 19.	FCGBP ZNF208 ZNF749 OR7A17 OR7A10	6.06e-05	284	51	5	15057824
Pubmed	The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice.	TIMM23B TIMM23	7.54e-05	9	51	2	19752021
Pubmed	Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs.	BMI1 PCGF2	7.54e-05	9	51	2	23523425
Pubmed	Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.	BMI1 PCGF2	9.42e-05	10	51	2	16687444
Pubmed	The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.	BMI1 PCGF2	9.42e-05	10	51	2	19585519
Pubmed	Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes.	BMI1 PCGF2	9.42e-05	10	51	2	16786585
Pubmed	A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.	BMI1 PCGF2	9.42e-05	10	51	2	20808772
Pubmed	Mitocytosis, a migrasome-mediated mitochondrial quality-control process.	TIMM23B TIMM23	9.42e-05	10	51	2	34048705
Pubmed	Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.	BMI1 PCGF2	1.15e-04	11	51	2	12183370
Pubmed	Proteomic analysis of the mouse liver mitochondrial inner membrane.	TIMM23B SFXN2 TIMM23 HADHA	1.29e-04	175	51	4	12865426
Pubmed	Lsh controls Hox gene silencing during development.	BMI1 PCGF2	1.38e-04	12	51	2	17726103
Pubmed	Identification of ligands for olfactory receptors by functional expression of a receptor library.	OR7A17 OR7A10	1.38e-04	12	51	2	9875846
Pubmed	Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.	BMI1 PCGF2	1.38e-04	12	51	2	20543829
Pubmed	Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.	BMI1 PCGF2	1.38e-04	12	51	2	19636380
Pubmed	Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation.	TIMM23B TIMM23	1.63e-04	13	51	2	10920231
Pubmed	PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification.	BMI1 PCGF2	1.63e-04	13	51	2	29727681
Pubmed	Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy.	BMI1 PCGF2	1.63e-04	13	51	2	11950896
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR7A17 OR7A10	1.63e-04	13	51	2	11014824
Pubmed	Genetic and structural characterization of the human mitochondrial inner membrane translocase.	TIMM23B TIMM23	1.90e-04	14	51	2	10339406
Pubmed	Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.	OR7A17 OR7A10	1.90e-04	14	51	2	7528109
Pubmed	PRC1 preserves epidermal tissue integrity independently of PRC2.	BMI1 PCGF2	1.90e-04	14	51	2	30567998
Pubmed	Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor.	BMI1 PCGF2	2.19e-04	15	51	2	20601937
Pubmed	Homeotic transformations of the axial skeleton of YY1 mutant mice and genetic interaction with the Polycomb group gene Ring1/Ring1A.	BMI1 PCGF2	2.50e-04	16	51	2	16624538
Pubmed	The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.	BMI1 PCGF2	2.50e-04	16	51	2	12167701
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR7A17 OR7A10	2.83e-04	17	51	2	20668191
Pubmed	Olfactory receptors and signalling elements in the Grueneberg ganglion.	OR7A17 OR7A10	2.83e-04	17	51	2	16805845
Pubmed	Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification.	TIMM23B TIMM23	2.83e-04	17	51	2	11709546
Pubmed	Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression.	BMI1 PCGF2	3.18e-04	18	51	2	11290297
Pubmed	Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.	BMI1 PCGF2	3.55e-04	19	51	2	16359901
Pubmed	PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.	BMI1 PCGF2	4.35e-04	21	51	2	18311137
Pubmed	SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.	BMI1 PCGF2	4.35e-04	21	51	2	37014752
Pubmed	Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.	TIMM23B TIMM23	4.78e-04	22	51	2	11431695
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR7A17 OR7A10	5.23e-04	23	51	2	10706615
Pubmed	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.	OR7A17 OR7A10	5.70e-04	24	51	2	9119360
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR7A17 OR7A10	7.23e-04	27	51	2	32061665
Pubmed	SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.	BMI1 PCGF2	7.23e-04	27	51	2	25703348
Pubmed	Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.	BMI1 PCGF2	8.93e-04	30	51	2	37158107
Pubmed	Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.	OR7A17 OR7A10	1.08e-03	33	51	2	17350283
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	PCGF2 WIZ SLC4A5	1.20e-03	142	51	3	11812828
Pubmed	Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.	TIMM23B TIMM23 HADHA	1.30e-03	146	51	3	29509794
Pubmed	The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development.	TIMM23B TIMM23	1.43e-03	38	51	2	33913477
Cytoband	Ensembl 112 genes in cytogenetic band chr2p23	KRTCAP3 SLC35F6 HADHA	6.22e-04	149	51	3	chr2p23
Cytoband	1q23.1	OR10K2 OR10T2	1.21e-03	46	51	2	1q23.1
Cytoband	19p13.12	OR7A17 OR7A10	1.43e-03	50	51	2	19p13.12
Cytoband	2p23.3	KRTCAP3 SLC35F6	2.63e-03	68	51	2	2p23.3
GeneFamily	CD molecules\|Tetraspanins	TSPAN8 TSPAN32 TSPAN33	3.80e-05	33	36	3	768
GeneFamily	Ring finger proteins\|Polycomb group ring fingers	BMI1 PCGF2	8.04e-05	7	36	2	61
GeneFamily	Solute carriers	SLC6A11 SLC44A1 SLC22A15 SLC4A5 SLC16A10	1.05e-03	395	36	5	752
GeneFamily	Olfactory receptors, family 10	OR10K2 OR10T2	7.63e-03	66	36	2	157
Disease	Myasthenic Syndromes, Congenital, Slow Channel	DPAGT1 CHRNG	2.94e-04	16	47	2	C0751885
Disease	Congenital Myasthenic Syndromes, Postsynaptic	DPAGT1 CHRNG	3.33e-04	17	47	2	C0751883
Disease	Congenital Myasthenic Syndromes, Presynaptic	DPAGT1 CHRNG	4.17e-04	19	47	2	C0751884
Disease	Myasthenic Syndromes, Congenital	DPAGT1 CHRNG	6.70e-04	24	47	2	C0751882
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS CLRN1	8.50e-04	27	47	2	DOID:10584 (implicated_via_orthology)
Disease	muscular atrophy (biomarker_via_orthology)	TIMM23B TIMM23	9.81e-04	29	47	2	DOID:767 (biomarker_via_orthology)
Disease	Disease Exacerbation	DPAGT1 BMI1 ING1	2.32e-03	165	47	3	C0235874
Disease	metachronous colorectal adenoma	SLC6A11 TSPAN32	2.35e-03	45	47	2	EFO_0803377
Disease	Retinitis pigmentosa	EYS CLRN1	6.24e-03	74	47	2	cv:C0035334
Disease	esophagus squamous cell carcinoma (is_marker_for)	BMI1 SLC16A10	6.24e-03	74	47	2	DOID:3748 (is_marker_for)
Disease	mean corpuscular hemoglobin concentration	DPAGT1 SFXN2 PFAS TSPAN32 PIGO SLC16A10	7.88e-03	1105	47	6	EFO_0004528
Disease	mean reticulocyte volume	DPAGT1 SYN3 TSPAN32 PIGO SLC16A10	8.62e-03	799	47	5	EFO_0010701

Protein segments in the cluster

Peptide	Gene	Start	Entry
FCALAMVLCDPGEAF	ACCSL	246	Q4AC99
LLMADDLGVGDLCCY	ARSH	11	Q5FYA8
NFVLGFFCCFMGCDL	CDIP1	161	Q9H305
CFLAMLSLFICGTAG	CHRNG	476	P07510
FCGIDLLIMDDGSFV	RIMKLA	256	Q8IXN7
KLQGGFMLCFLDDGC	MORC1	56	Q86VD1
GLVCCECFLLGSMAY	OR8I2	106	Q8N0Y5
GFMTCSIGLLCGDEI	EYS	1226	Q5T1H1
LMCVLCGGYFIDATT	BMI1	16	P35226
ALLAICCMIFLGFAD	DPAGT1	101	Q9H3H5
VLCSIFGICMVFSGL	PTGFR	106	P43088
MLGLLQFDSGFICLC	KBTBD7	601	Q8WVZ9
LGFACTNCLLIAVMG	OR10T2	106	Q8NGX3
CLGGAECFLLAVMSY	OR2AE1	106	Q8NHA4
LMCALCGGYFIDATT	PCGF2	16	P35227
FLGCATQMFLACTFG	OR5T1	106	Q8NG75
ESFFKGCVLDVCMGG	FCGBP	4301	Q9Y6R7
GCFIAGADINMLAAC	HADHA	96	P40939
ILFCIGMGFICGFSI	SLC44A1	36	Q8WWI5
AFLCLGGLACLIVMF	SLC22A15	371	Q8IZD6
LLMSAGEAALSGYCC	KRTCAP3	171	Q53RY4
GCAIQMFSFLFLGCS	OR10K2	96	Q6IF99
ACDIGLDACLGQMFL	OR52M1	91	Q8NGK5
VDSCSEMFGGLDICA	SYN3	336	O14994
SGCFLIFMVPVACGL	SFXN2	271	Q96NB2
AITGMGLCFRCLLFS	ING1	26	Q9UK53
GCITQMCFFLLFVGL	OR7A10	96	O76100
GCITQMCFFVLFGGL	OR7A17	96	O14581
FSLMRCDFCGAGFDT	WIZ	766	O95785
MALFGFCSSCGELQL	SPTBN5	896	Q9NRC6
CVFCMGLLTASIFLG	CLEC9A	41	Q6UXN8
SFISGSCGCLVMILF	CLRN1	141	P58418
VGVLMFLLTFCGCIG	TSPAN33	71	Q86UF1
SGLVMILFSACCICG	TMEM196	71	Q5HYL7
CSECGKLFMDSFTLG	ZNF749	356	O43361
AALLFCCMILFGLGV	CD96	526	P40200
MAGGFLCFSLAFCAQ	TSPAN32	91	Q96QS1
VTCLLEMAFAGNCGL	PFAS	916	O15067
MLCCLNSGTSFVAGF	SLC6A11	336	P48066
SILMFCGIDACFGLE	SLC4A5	786	Q9BY07
CGIDLLMKDDGSFCV	RIMKLB	261	Q9ULI2
GRFELAFFTIGGCCM	TIMM23B	71	Q5SRD1
AVGMFLGEFSCLAAF	SLC35F6	51	Q8N357
CEECGKGFSMFSILT	ZNF208	891	O43345
CEECGKGFVMFSILA	ZNF208	1171	O43345
MAGGTALLAASCFIC	PIGO	451	Q8TEQ8
STGLAMVGAICDFCE	ZNF330	91	Q9Y3S2
MGFRLLCCVAFCLLG	TRBV9	1	A0A0B4J1U6
SGLLLGLCMIFVADC	TMX1	191	Q9H3N1
GRFELAFFTIGGCCM	TIMM23	71	O14925
AVGAIIMILGFLGCC	TSPAN8	61	P19075
IAVCLIMGLFDGCFI	SLC16A10	386	Q8TF71