Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	protein localization to Golgi apparatus	GAK COG7 VPS13C VPS13D RIPOR1	3.23e-07	32	94	5	GO:0034067
GeneOntologyBiologicalProcess	protein localization to organelle	GAK MCPH1 COG7 VPS13C SYNE1 PEX13 WNK1 ESCO2 FSIP2 VPS13D TRIM28 NPAP1 MFN2 MACF1 OS9 RIPOR1 IFT80 PCM1	1.80e-06	1091	94	18	GO:0033365
GeneOntologyBiologicalProcess	intracellular transport	UBE2J1 ABCA2 GAK COPZ2 COG7 VPS13C SYNE1 PLEKHF1 PEX13 WNK1 RSRC1 TMEM106B NEFL VPS13D TRIM28 NPAP1 OS9 RIPOR1 IFT80 PCM1	1.08e-05	1496	94	20	GO:0046907
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	POLD1 WRNIP1 POLK REV1	6.75e-05	48	94	4	GO:0000731
GeneOntologyBiologicalProcess	regulation of organelle organization	TMEM67 MCPH1 VPS13C SYNE1 PECAM1 ITGB3 TMEM106B ARHGAP6 VPS13D XIRP2 ANAPC1 TRIM28 NFRKB SENP6 MFN2 ROCK1 ANAPC4	1.07e-04	1342	94	17	GO:0033043
GeneOntologyBiologicalProcess	cell-substrate junction assembly	LAMC1 ITGB3 ARHGAP6 MACF1 ROCK1	1.36e-04	108	94	5	GO:0007044
GeneOntologyBiologicalProcess	cell-substrate junction organization	LAMC1 ITGB3 ARHGAP6 MACF1 ROCK1	1.83e-04	115	94	5	GO:0150115
GeneOntologyBiologicalProcess	protein retention in Golgi apparatus	VPS13C VPS13D	2.04e-04	5	94	2	GO:0045053
GeneOntologyBiologicalProcess	lncRNA transcription	NFATC2 CELF3	2.04e-04	5	94	2	GO:0140742
GeneOntologyBiologicalProcess	error-free translesion synthesis	POLD1 REV1	2.04e-04	5	94	2	GO:0070987
GeneOntologyBiologicalProcess	translesion synthesis	POLD1 POLK REV1	2.21e-04	26	94	3	GO:0019985
GeneOntologyBiologicalProcess	neuronal stem cell population maintenance	MCPH1 ASPM PCM1	2.21e-04	26	94	3	GO:0097150
GeneOntologyBiologicalProcess	microtubule-based process	TMEM67 MCPH1 PEX13 FSIP2 NEFL CELF3 ASPM SENP6 MACF1 ROCK1 IFT80 DNAH6 HYDIN PCM1	3.01e-04	1058	94	14	GO:0007017
GeneOntologyBiologicalProcess	nucleotide-excision repair, DNA gap filling	POLD1 POLK	3.05e-04	6	94	2	GO:0006297
GeneOntologyBiologicalProcess	chemorepulsion of axon	RYK UNC5C	3.05e-04	6	94	2	GO:0061643
Domain	UmuC	ESCO2 POLK REV1	2.29e-06	6	92	3	IPR001126
Domain	ASH	ASPM HYDIN	2.40e-05	2	92	2	IPR031549
Domain	ASH	ASPM HYDIN	2.40e-05	2	92	2	PF15780
Domain	VPS13	VPS13C VPS13D	7.18e-05	3	92	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13D	7.18e-05	3	92	2	PF16910
Domain	VPS13	VPS13C VPS13D	7.18e-05	3	92	2	PF16908
Domain	VPS13_N2	VPS13C VPS13D	7.18e-05	3	92	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13D	7.18e-05	3	92	2	IPR031642
Domain	IMS	POLK REV1	1.43e-04	4	92	2	PF00817
Domain	VPS13_C	VPS13C VPS13D	1.43e-04	4	92	2	PF16909
Domain	IMS_C	POLK REV1	1.43e-04	4	92	2	PF11799
Domain	SHR-BD	VPS13C VPS13D	1.43e-04	4	92	2	IPR009543
Domain	UMUC	POLK REV1	1.43e-04	4	92	2	PS50173
Domain	-	POLK REV1	1.43e-04	4	92	2	3.30.1490.100
Domain	VPS13_C	VPS13C VPS13D	1.43e-04	4	92	2	IPR031645
Domain	SHR-BD	VPS13C VPS13D	1.43e-04	4	92	2	PF06650
Domain	DNA_pol_Y-fam_little_finger	POLK REV1	1.43e-04	4	92	2	IPR017961
Domain	ZnF_Rad18	WRNIP1 POLK	2.38e-04	5	92	2	SM00734
Domain	Znf_Rad18_put	WRNIP1 POLK	2.38e-04	5	92	2	IPR006642
Domain	BRCT_2	MCPH1 REV1	2.38e-04	5	92	2	PF16589
Domain	CH	EHBP1 SYNE1 ASPM MACF1	2.97e-04	65	92	4	SM00033
Domain	CH	EHBP1 SYNE1 ASPM MACF1	3.94e-04	70	92	4	PF00307
Domain	-	EHBP1 SYNE1 ASPM MACF1	4.16e-04	71	92	4	1.10.418.10
Domain	UBA	RSC1A1 USP5 VPS13D	4.26e-04	30	92	3	SM00165
Domain	CH	EHBP1 SYNE1 ASPM MACF1	4.63e-04	73	92	4	PS50021
Domain	CH-domain	EHBP1 SYNE1 ASPM MACF1	5.13e-04	75	92	4	IPR001715
Domain	VPS13_N	VPS13C VPS13D	6.59e-04	8	92	2	IPR026854
Domain	Chorein_N	VPS13C VPS13D	6.59e-04	8	92	2	PF12624
Domain	UBA	RSC1A1 USP5 VPS13D	1.32e-03	44	92	3	IPR015940
Domain	UBA	RSC1A1 USP5 VPS13D	1.60e-03	47	92	3	PS50030
Domain	EGF_extracell	ADAM11 ITGB3 TENM4	3.23e-03	60	92	3	IPR013111
Domain	EGF_2	ADAM11 ITGB3 TENM4	3.23e-03	60	92	3	PF07974
Domain	BRCT	MCPH1 REV1	3.89e-03	19	92	2	PF00533
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GAK IGHV1-69 SYNE1 WRNIP1 ADGRL1 EFHD2 HDHD2 EPN2 NEFL USP5 CRYM TENM4 TRIM28 PRRC2C MACF1 DNAH6 RPL6 PCM1	1.28e-07	1431	100	18	37142655
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	METTL3 GAK RBBP8 WNK1 ANAPC1 PRRC2C ASPM SENP6 MACF1 ROCK1 POLK PCM1	1.33e-07	588	100	12	38580884
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	UBE2J1 GAK VPS13C WRNIP1 PEX13 EFHD2 WNK1 ANAPC1 NFRKB OS9 ROCK1 PCM1	1.36e-06	733	100	12	34672954
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 RBBP8 UBR4 TRPS1 LAMC1 ANKHD1 SATB1 ANAPC1 PCM1	3.48e-06	418	100	9	34709266
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GAK RPN2 UBR4 LAMC1 PSME2 ANKHD1 WNK1 TMEM106B PRRC2C MFN2 MACF1 OS9 SCARA3 RPL6 PCM1	4.49e-06	1297	100	15	33545068
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAK RPN2 POLD1 UBR4 WRNIP1 LAMC1 EFHD2 ANKHD1 USP5 TRIM28 OS9 PCM1 SLC27A3	4.52e-06	974	100	13	28675297
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	RPN2 LAMC1 PSME2 WNK1 NEFL USP5 PRRC2C MACF1 ROCK1 DNAH6 RPL6 BRWD1	5.95e-06	847	100	12	35235311
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	POLD1 WRNIP1 LRRC40 ANKHD1 ANAPC1 PRRC2C MFN2	6.69e-06	242	100	7	34011540
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 COBLL1 LAMC1 WNK1 RSRC1 EPN2 FSIP2 VPS13D PRRC2C MACF1 RGL2 PCM1	7.02e-06	861	100	12	36931259
Pubmed	RNA m6A methylation regulates the ultraviolet-induced DNA damage response.	METTL3 POLK	8.18e-06	2	100	2	28297716
Pubmed	Primary microcephaly: microcephalin and ASPM determine the size of the human brain.	MCPH1 ASPM	8.18e-06	2	100	2	12571366
Pubmed	Tone and genes: New cross-linguistic data and methods support the weak negative effect of the "derived" allele of ASPM on tone, but not of Microcephalin.	MCPH1 ASPM	8.18e-06	2	100	2	34191836
Pubmed	Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells.	TRIM28 MFN2	8.18e-06	2	100	2	27364555
Pubmed	Investigation of MCPH1 G37995C and ASPM A44871G polymorphisms and brain size in a healthy cohort.	MCPH1 ASPM	8.18e-06	2	100	2	17566767
Pubmed	USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1.	USP5 CD274	8.18e-06	2	100	2	34741014
Pubmed	METTL3 confers protection against mitochondrial dysfunction and cognitive impairment in an Alzheimer disease mouse model by upregulating Mfn2 via N6-methyladenosine modification.	METTL3 MFN2	8.18e-06	2	100	2	38408379
Pubmed	No evidence that polymorphisms of brain regulator genes Microcephalin and ASPM are associated with general mental ability, head circumference or altruism.	MCPH1 ASPM	8.18e-06	2	100	2	17251122
Pubmed	Selective dimerization of a C2H2 zinc finger subfamily.	TRPS1 IKZF1	8.18e-06	2	100	2	12620233
Pubmed	IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.	UBR4 IKZF1	8.18e-06	2	100	2	38885295
Pubmed	A common SNP of MCPH1 is associated with cranial volume variation in Chinese population.	MCPH1 ASPM	8.18e-06	2	100	2	18204051
Pubmed	Deregulation of microcephalin and ASPM expression are correlated with epithelial ovarian cancer progression.	MCPH1 ASPM	8.18e-06	2	100	2	24830737
Pubmed	Comprehensive characterization of tumor microenvironment and m6A RNA methylation regulators and its effects on PD-L1 and immune infiltrates in cervical cancer.	METTL3 CD274	8.18e-06	2	100	2	36091006
Pubmed	Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus.	POLK REV1	8.18e-06	2	100	2	19628463
Pubmed	Two novel Krüppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1beta/KRIP-1).	ZNF300 TRIM28	8.18e-06	2	100	2	10347202
Pubmed	Normal variants of Microcephalin and ASPM do not account for brain size variability.	MCPH1 ASPM	8.18e-06	2	100	2	16687438
Pubmed	The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence.	MCPH1 ASPM	8.18e-06	2	100	2	17220170
Pubmed	Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control.	UBE2J1 RPN2 OS9	1.02e-05	15	100	3	21857022
Pubmed	A human MAP kinase interactome.	EHBP1 SYNE1 COBLL1 ADGRL1 WNK1 TRIM28 MACF1 OS9 RGL2	1.17e-05	486	100	9	20936779
Pubmed	Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	MCPH1 RBBP8 ASPM	1.26e-05	16	100	3	20301772
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RPN2 POLD1 UBR4 TRMT1 EFHD2 LRRC40 PSME2 ANKHD1 WNK1 RSRC1 USP5 TRIM28 PRRC2C MACF1 RPL6	1.27e-05	1415	100	15	28515276
Pubmed	Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.	UBR4 ANAPC1 ANAPC4	1.52e-05	17	100	3	29033132
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EHBP1 GAK PSME2 ANKHD1 WNK1 TRIM28 PRRC2C SENP6 MACF1 RPL6 PCM1 ANAPC4	1.58e-05	934	100	12	33916271
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	POLD1 TRPS1 WRNIP1 ANKHD1 MLH3 ANAPC1 TRIM28 NFRKB ASPM MACF1 PCM1 ANAPC4 BRWD1	1.92e-05	1116	100	13	31753913
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPN2 UBR4 ANKHD1 NEFL USP5 ANAPC1 PRRC2C MACF1 RPL6 PCM1	1.93e-05	653	100	10	22586326
Pubmed	IKZF1 selectively enhances homologous recombination repair by interacting with CtIP and USP7 in multiple myeloma.	RBBP8 IKZF1	2.45e-05	3	100	2	35414773
Pubmed	PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis.	PECAM1 ITGB3	2.45e-05	3	100	2	10982404
Pubmed	Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.	TMEM106B UNC5C	2.45e-05	3	100	2	28441426
Pubmed	Functional Domain Mapping of Werner Interacting Protein 1 (WRNIP1).	POLD1 WRNIP1	2.45e-05	3	100	2	35110507
Pubmed	Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ.	POLK REV1	2.45e-05	3	100	2	22700975
Pubmed	DNA polymerases eta and kappa exchange with the polymerase delta holoenzyme to complete common fragile site synthesis.	POLD1 POLK	2.45e-05	3	100	2	28605669
Pubmed	Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and disease.	VPS13D MFN2	2.45e-05	3	100	2	34019822
Pubmed	METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1.	METTL3 CD274	2.45e-05	3	100	2	34476262
Pubmed	Genetic heterogeneity in Pakistani microcephaly families revisited.	MCPH1 ASPM	2.45e-05	3	100	2	28004384
Pubmed	Associations of combined polymorphisms of the platelet membrane glycoproteins Ia and IIIa and the platelet-endothelial cell adhesion molecule-1 and P-Selectin genes with IVF implantation failures.	PECAM1 ITGB3	2.45e-05	3	100	2	28388872
Pubmed	Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.	POLK REV1	2.45e-05	3	100	2	26982350
Pubmed	Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.	POLK REV1	2.45e-05	3	100	2	25080294
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 XIRP2 MACF1	2.54e-05	20	100	3	21689717
Pubmed	Defining the membrane proteome of NK cells.	ABCA2 GAK RPN2 POLD1 UBR4 WRNIP1 PEX13 LRRC40 PSME2 PRRC2C RPL6 PCM1 SLC27A3	3.07e-05	1168	100	13	19946888
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EHBP1 UBE2J1 RPN2 COBLL1 LRRC40 TRIM28 PRRC2C MACF1 ROCK1 RPL6	3.83e-05	708	100	10	39231216
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	EHBP1 UBE2J1 GAK VPS13C EFHD2 VPS13D PRRC2C SCARA3 PCM1	3.95e-05	568	100	9	37774976
Pubmed	Microcephaly genes and risk of late-onset Alzheimer disease.	MCPH1 ASPM	4.89e-05	4	100	2	21297427
Pubmed	Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers.	TRPS1 IKZF1	4.89e-05	4	100	2	15491138
Pubmed	Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death.	PECAM1 ROCK1	4.89e-05	4	100	2	12832488
Pubmed	Polymorphisms of Platelet Glycoprotein Receptors and Cell Adhesion Molecules in Fetuses with Fetal Growth Restriction and Their Mothers As Detected with Pyrosequencing.	PECAM1 ITGB3	4.89e-05	4	100	2	28358707
Pubmed	Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.	POLD1 WRNIP1	4.89e-05	4	100	2	15670210
Pubmed	Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.	POLK REV1	4.89e-05	4	100	2	15380106
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13D	4.89e-05	4	100	2	15498460
Pubmed	Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.	PECAM1 EPN2	4.89e-05	4	100	2	24311377
Pubmed	Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.	POLK REV1	4.89e-05	4	100	2	19170759
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	TMEM67 SYNE1	4.89e-05	4	100	2	19596800
Pubmed	Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ.	POLK REV1	4.89e-05	4	100	2	22859295
Pubmed	Sex-dependent association of common variants of microcephaly genes with brain structure.	MCPH1 ASPM	4.89e-05	4	100	2	20080800
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TRPS1 LAMC1 EYS TRIM28 PRRC2C MACF1 PCM1	5.08e-05	332	100	7	37433992
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	DPYS LAMC1 TENM4 ZNF292	5.39e-05	71	100	4	33541421
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	RBBP8 WNK1 VPS13D TRIM28 RPL6 PCM1	6.27e-05	235	100	6	30258100
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	COG7 POLD1 UBR4 WRNIP1 TRMT1 EFHD2 PSME2 WNK1 USP5 TRIM28 NFRKB MACF1 ROCK1 RIPOR1	7.22e-05	1455	100	14	22863883
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 SLC37A3 UBR4 TRMT1 ADGRL1 ANKHD1 WNK1 TRIM28 MFN2 RIPOR1 RGL2 SCARA3	8.01e-05	1105	100	12	35748872
Pubmed	Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms.	ITGB3 ROCK1	8.14e-05	5	100	2	23726972
Pubmed	The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression.	ANAPC1 ANAPC4	8.14e-05	5	100	2	19826416
Pubmed	Primordial germ cell DNA demethylation and development require DNA translesion synthesis.	POLK REV1	8.14e-05	5	100	2	38702312
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	GAK ANKHD1 ITGB3 USP5 TRIM28 PRRC2C MACF1	8.43e-05	360	100	7	33111431
Pubmed	UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.	RBBP8 ANKHD1 TRIM28 MACF1 RPL6	8.82e-05	155	100	5	34921745
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	UBE2J1 GAK RPN2 POLD1 SYNE1 UBR4 LAMC1 LRRC40 ASPM MACF1 OS9 IFT80 RPL6 PCM1	9.09e-05	1487	100	14	33957083
Pubmed	A protein interaction landscape of breast cancer.	GAK RBBP8 UBR4 MACF1 OS9 RGL2 RPL6 PCM1 ANAPC4	9.16e-05	634	100	9	34591612
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SYNE1 UBR4 EFHD2 NEFL ANAPC1 TRIM28 PRRC2C MFN2 MACF1 ROCK1 PCM1	1.04e-04	963	100	11	28671696
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	METTL3 COBLL1 TRMT1 EFHD2 WNK1 USP5 TRIM28 PCM1	1.05e-04	503	100	8	16964243
Pubmed	Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.	MCPH1 RYK ROCK1	1.08e-04	32	100	3	20056645
Pubmed	The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1.	POLK REV1	1.22e-04	6	100	2	26903512
Pubmed	Interaction of hREV1 with three human Y-family DNA polymerases.	POLK REV1	1.22e-04	6	100	2	15189446
Pubmed	WNK1 protein kinase regulates embryonic cardiovascular development through the OSR1 signaling cascade.	PECAM1 WNK1	1.22e-04	6	100	2	23386621
Pubmed	Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis.	POLK REV1	1.22e-04	6	100	2	14657033
Pubmed	Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).	UBE2J1 OS9	1.22e-04	6	100	2	28827405
Pubmed	Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta.	PECAM1 ITGB3	1.22e-04	6	100	2	23789102
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	EFHD2 LRRC40 WNK1 USP5 NFRKB RPL6	1.26e-04	267	100	6	33417871
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	UBR4 WRNIP1 USP5 ANAPC1 HYDIN	1.36e-04	170	100	5	23314748
Pubmed	The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C.	ANAPC1 ANAPC4	1.70e-04	7	100	2	27939943
Pubmed	Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation.	POLK REV1	1.70e-04	7	100	2	24038355
Pubmed	Clinical and genetic spectra of Charcot-Marie-Tooth disease in Chinese Han patients.	NEFL MFN2	1.70e-04	7	100	2	27862672
Pubmed	Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling.	ITGB3 ROCK1	1.70e-04	7	100	2	25911094
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 ADGRL1 TENM4 PRRC2C MFN2 MACF1 RIPOR1	1.80e-04	407	100	7	12693553
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	GAK EFHD2 ANKHD1 ANAPC1 TRIM28 PRRC2C NFRKB PCM1	1.91e-04	549	100	8	38280479
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	POLD1 EFHD2 IKZF1 RSRC1 USP5 TRIM28 PRRC2C PCM1 REV1	1.94e-04	701	100	9	30196744
Pubmed	Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.	WRNIP1 EPN2 USP5 MFN2	1.96e-04	99	100	4	29676259
Pubmed	Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression.	RBBP8 IKZF1	2.27e-04	8	100	2	11959865
Pubmed	TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.	PECAM1 TRIM28	2.27e-04	8	100	2	22110054
Pubmed	A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder.	PECAM1 LAMC1	2.27e-04	8	100	2	32439764
Pubmed	UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy.	PECAM1 UBR4	2.27e-04	8	100	2	23431188
Pubmed	Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.	ANAPC1 ANAPC4	2.27e-04	8	100	2	20686030
Pubmed	N6 -methyladenosine-modified lncRNA ARHGAP5-AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma.	METTL3 TRIM28	2.27e-04	8	100	2	36354136
Pubmed	Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation.	METTL3 USP5	2.27e-04	8	100	2	33217317
Cytoband	2q24.3	COBLL1 XIRP2	5.53e-04	16	100	2	2q24.3
Cytoband	1q31	LAMC1 ASPM	7.84e-04	19	100	2	1q31
Cytoband	8p21	NEFL SCARA3	8.70e-04	20	100	2	8p21
Cytoband	19q12	PLEKHF1 VSTM2B	8.70e-04	20	100	2	19q12
GeneFamily	DNA polymerases	POLD1 POLK REV1	7.81e-05	23	66	3	535
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	IKZF1 WNK1 NEFL TRIM28 HYDIN	5.19e-04	181	66	5	694
GeneFamily	Anaphase promoting complex \|Tetratricopeptide repeat domain containing	ANAPC1 ANAPC4	1.16e-03	14	66	2	402
GeneFamily	Adenosine receptors\|V-set domain containing	BTNL8 VSTM2B CD300LB CD274	2.97e-03	163	66	4	590
Coexpression	GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_UP	UBR4 IKZF1 PRRC2C ROCK1 RPL6 CDH18 ZNF292	1.01e-05	197	99	7	M6191
Coexpression	GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP	METTL3 UBR4 TRMT1 PSME2 SATB1 TRIM28 RGL2	1.12e-05	200	99	7	M3035
Coexpression	GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN	SYNE1 IKZF1 VPS13D SENP6 OS9 RGL2 ZNF292	1.12e-05	200	99	7	M7441
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts\|Liver / Manually curated celltypes from each tissue	UBE2J1 IGHV1-69 COBLL1 ESCO2 ASPM IGHV4-59	2.99e-06	177	100	6	1d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C SATB1 PRRC2C CELF3 MACF1 PCM1	5.22e-06	195	100	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C SATB1 PRRC2C CELF3 MACF1 PCM1	5.22e-06	195	100	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	SYNE1 PLEKHF1 ADGRL1 EFHD2 NFATC2 MACF1	5.22e-06	195	100	6	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 PLEKHF1 ADGRL1 EFHD2 NFATC2 MACF1	5.37e-06	196	100	6	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 PLEKHF1 ADGRL1 EFHD2 NFATC2 MACF1	5.37e-06	196	100	6	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 PLEKHF1 ADGRL1 EFHD2 NFATC2 MACF1	5.37e-06	196	100	6	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 PLEKHF1 ADGRL1 EFHD2 NFATC2 MACF1	5.37e-06	196	100	6	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 IKZF1 PRRC2C MACF1 PCM1 ZNF292	5.53e-06	197	100	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	UBE2J1 RPN2 COBLL1 LAMC1 ASPM IGHV4-59	5.53e-06	197	100	6	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	VPS13C TMEM106B PRRC2C ROCK1 ZNF292 BRWD1	5.86e-06	199	100	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	VPS13C PRRC2C MACF1 ROCK1 PCM1 ZNF292	6.03e-06	200	100	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UBE2J1 RBBP8 IGHV1-69 CRYM LRRD1	3.55e-05	165	100	5	6e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 IKZF1 PRRC2C MACF1 PCM1	4.21e-05	171	100	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 PLEKHF1 EFHD2 NFATC2 ASPM	4.32e-05	172	100	5	86f52f486d67217fc1b8443ab362c975df2974a4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 PLEKHF1 EFHD2 NFATC2 ASPM	4.32e-05	172	100	5	fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 PLEKHF1 EFHD2 NFATC2 ASPM	4.32e-05	172	100	5	e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C XIRP2 PRRC2C MACF1 PCM1	4.82e-05	176	100	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C SYNE1 PRRC2C CD274 PCM1	5.09e-05	178	100	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARHGAP6 CRYM MLH3 XIRP2 CGRRF1	5.37e-05	180	100	5	1be264962fd4ed0bb59f9b8a6956c4239ca32e05
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP6 CRYM MLH3 XIRP2 CGRRF1	5.37e-05	180	100	5	5568063c2518fadb638e665635061ec10d00fb6a
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C TRPS1 PRRC2C MACF1 PCM1	5.66e-05	182	100	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EFHD2 NEFL CRYM ASPM DNAH6	5.80e-05	183	100	5	3ebe334ad570e3525341badb558f369c61daf3d3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SATB1 PRRC2C NFRKB GTSCR1 BRWD1	5.96e-05	184	100	5	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	SYNE1 ADGRL1 EFHD2 NFATC2 MACF1	5.96e-05	184	100	5	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C TRPS1 PRRC2C MACF1 PCM1	6.11e-05	185	100	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLEKHF1 TRPS1 EFHD2 IKZF1 ASPM	6.11e-05	185	100	5	326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SATB1 PRRC2C MACF1 RPL6 BRWD1	6.27e-05	186	100	5	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	droplet-Spleen-nan-3m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SATB1 PRRC2C MACF1 RPL6 BRWD1	6.43e-05	187	100	5	91c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SATB1 PRRC2C MACF1 RPL6 BRWD1	6.43e-05	187	100	5	382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA2 SYNE1 PLEKHF1 EFHD2 NFATC2	6.59e-05	188	100	5	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	RBBP8 COBLL1 WNK1 ARHGAP6 UNC5C	6.59e-05	188	100	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA2 SYNE1 PLEKHF1 EFHD2 NFATC2	6.59e-05	188	100	5	8155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	73ee4cfb1057832f700be59b6917dedde3e89880
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	31594cc59eb1c5b01407dfd72b1487ecca8bf5ec
ToppCell	COVID-19_Mild-Lymphoid_P\|COVID-19_Mild / Disease group, lineage and cell class	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	0b3d3bd697e79decae7e21c513fab9da3b2a47c5
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	c296660061b46e3abae1e7cf29df20274e5a8add
ToppCell	COVID-19_Mild-Lymphoid_P-Plasmablast\|COVID-19_Mild / Disease group, lineage and cell class	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	254f058850b41a5974a380f3710db7c01a51fb6b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 COBLL1 WNK1 ARHGAP6 UNC5C	6.76e-05	189	100	5	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	f2daf4889ef98bbefe3e44832618ac102a75b4d9
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	UBE2J1 COBLL1 LAMC1 ASPM IGHV4-59	6.76e-05	189	100	5	9de17ade3cc3e9cd1394338bd048fb1ce64ac50f
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	UBE2J1 COPZ2 RPN2 PECAM1 IGHV4-59	6.93e-05	190	100	5	76b747bafff09bf8375a5717c9f213cbfb405bac
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	BTNL8 SYNE1 PECAM1 ARHGAP6 CD274	6.93e-05	190	100	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	mild_COVID-19_(asymptomatic)-Platelet\|World / disease group, cell group and cell class (v2)	DPYS ITGB3 ARHGAP6 MLH3 XIRP2	6.93e-05	190	100	5	7aaf82f0c235363afb95cf1fa51c2a5b070b1af8
ToppCell	severe-Platelet\|severe / disease stage, cell group and cell class	ITGB3 ARHGAP6 MLH3 XIRP2 CGRRF1	6.93e-05	190	100	5	497ec3fe4dd6f1b4fa6e76d9ac07df497efce7a2
ToppCell	(210)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	PLEKHF1 EFHD2 EYS NFATC2 MACF1	7.28e-05	192	100	5	08dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	7.28e-05	192	100	5	ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	7.28e-05	192	100	5	58a7829b411b02b422ef75e2277a868969cc23e8
ToppCell	COVID-19_Severe-Lymphoid_P\|COVID-19_Severe / Disease group, lineage and cell class	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.28e-05	192	100	5	3d0240491296757b3125f6e861bbaca06bbc5068
ToppCell	(21)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	PLEKHF1 EFHD2 EYS NFATC2 MACF1	7.28e-05	192	100	5	b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell	COVID-19_Severe-Lymphoid_P-Plasmablast\|COVID-19_Severe / Disease group, lineage and cell class	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.28e-05	192	100	5	90af8dad4e6f80b5ecd62027deeb2e4cea6b24bb
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.46e-05	193	100	5	227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.46e-05	193	100	5	38bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.46e-05	193	100	5	3ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	EHBP1 WNK1 PRRC2C PCM1 ZNF292	7.46e-05	193	100	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	UBE2J1 RPN2 COBLL1 LAMC1 IGHV4-59	7.46e-05	193	100	5	7b4b0271e4fbece703876acb053ae236afb7cdba
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.46e-05	193	100	5	ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	7.46e-05	193	100	5	8f57b0473a2c2c07f83e5fe70f16862b1bb3b514
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 SATB1 TRIM28 PRRC2C RIPOR1	7.65e-05	194	100	5	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B_plasma\|lymph-node_spleen / Manually curated celltypes from each tissue	UBE2J1 RPN2 COBLL1 ESCO2 ASPM	7.65e-05	194	100	5	42f43cac0dec704afd18143192e3ab68360ea076
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 SATB1 TRIM28 PRRC2C RIPOR1	7.65e-05	194	100	5	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 SATB1 TRIM28 PRRC2C RIPOR1	7.65e-05	194	100	5	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 SYNE1 C1orf141 DNAH6 HYDIN	7.65e-05	194	100	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TRPS1 TENM4 UNC5C RPL6 CDH18	7.65e-05	194	100	5	85e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell	severe-Plasmablast\|severe / disease stage, cell group and cell class	UBE2J1 RPN2 COBLL1 PSME2 OS9	7.83e-05	195	100	5	e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	EFHD2 WNK1 NFATC2 ROCK1 ZNF292	7.83e-05	195	100	5	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	EFHD2 WNK1 NFATC2 ROCK1 ZNF292	8.03e-05	196	100	5	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 ASPM MACF1 DNAH6 HYDIN	8.03e-05	196	100	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COPZ2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.03e-05	196	100	5	d3bd8fab010e76024d7e06aba0ea5df3394f411f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COPZ2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.03e-05	196	100	5	77da6b1bcab45d376eb0368f540e0ed24ce98b42
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 ASPM MACF1 DNAH6 HYDIN	8.03e-05	196	100	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	UBE2J1 RPN2 LAMC1 ITGB3 IGHV4-59	8.03e-05	196	100	5	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 SYNE1 C1orf141 DNAH6 HYDIN	8.22e-05	197	100	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	Severe-Lymphoid-T-CD8_T\|Severe / Condition, Lineage, Cell class and cell subclass	ABCA2 SYNE1 PLEKHF1 IKZF1 NFATC2	8.22e-05	197	100	5	00d884ec591f63a345d7fd0a6b368f9da4b4c6ce
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.22e-05	197	100	5	a44501cac24c2f4a53b413e92bd060eed6514616
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 SYNE1 NPAP1 DNAH6 HYDIN	8.22e-05	197	100	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	UBE2J1 RPN2 COBLL1 ASPM IGHV4-59	8.22e-05	197	100	5	b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCell	Severe-CD8+_T_activated\|Severe / Disease group and Cell class	ABCA2 PLEKHF1 PECAM1 PSME2 NFATC2	8.22e-05	197	100	5	bb1e3e1d841c2c7141eb1099e7755860b168b6fc
ToppCell	T_cells-CTLs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.22e-05	197	100	5	2de34e20915a247bee75aa40495e23c20bb23e18
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	VPS13C SYNE1 MACF1 ROCK1 PCM1	8.42e-05	198	100	5	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	mild_COVID-19_(asymptomatic)-NK\|World / disease group, cell group and cell class (v2)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	7a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCell	mild-Lymphocytic-NK_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCell	T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SYNE1 PLEKHF1 IKZF1 NFATC2 MACF1	8.42e-05	198	100	5	1ca6cd8e75891fdfaddbb4a7342eec9ca4d11e5d
ToppCell	COVID-19_Severe-NK\|COVID-19_Severe / disease group, cell group and cell class	COPZ2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.42e-05	198	100	5	0cb88084eac25604ec8f9b1497fb8d2433f1971c
ToppCell	COVID_vent-Lymphocytic-Plasma_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	UBE2J1 RPN2 COBLL1 LAMC1 IGHV4-59	8.42e-05	198	100	5	e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.42e-05	198	100	5	a6b942fe850e287e1cb705684e29218072daf891
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	df399674345c45738d765a8354ea8d1484572c34
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.42e-05	198	100	5	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	severe-NK\|severe / disease stage, cell group and cell class	SYNE1 PLEKHF1 EFHD2 IKZF1 NFATC2	8.42e-05	198	100	5	cb505077dc5bdf3fdd513bb9032e32bb9644c004
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-B-Plasmablast\|COVID-19_Severe / Disease, condition lineage and cell class	UBE2J1 RPN2 COBLL1 LAMC1 ASPM	8.62e-05	199	100	5	e6422b65e22e5aa8dfaebdae5be76dd78b978604
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 PRRC2C MACF1 PCM1 ZNF292	8.62e-05	199	100	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	VPS13C TMEM106B VPS13D PRRC2C ROCK1	8.62e-05	199	100	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ABCA2 SYNE1 EFHD2 NFATC2 MACF1	8.62e-05	199	100	5	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SYNE1 PLEKHF1 EFHD2 NFATC2 MACF1	8.62e-05	199	100	5	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	COVID-19_Moderate-NK\|COVID-19_Moderate / disease group, cell group and cell class	COPZ2 SYNE1 PLEKHF1 EFHD2 NFATC2	8.62e-05	199	100	5	e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	VPS13C TMEM106B PRRC2C ROCK1 ZNF292	8.62e-05	199	100	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ABCA2 SYNE1 EFHD2 NFATC2 MACF1	8.62e-05	199	100	5	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 MACF1 ROCK1 ZNF292	1.44e-04	49	59	4	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drug	Clorgyline	VPS13C COBLL1 TMEM106B SENP6 IFT80 POLK PCM1 ZNF292 BRWD1	4.29e-08	168	97	9	ctd:D003010
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	VPS13C COBLL1 UBR4 TRPS1 VPS13D MACF1 RIPOR1 BRWD1	1.62e-06	191	97	8	4168_DN
Drug	Guanine	POLD1 POLK REV1	8.80e-06	10	97	3	ctd:D006147
Drug	Vincristine	UBE2J1 METTL3 RBBP8 UBR4 PEX13 ANKHD1 WNK1 ESCO2 VPS13D NFATC2 XIRP2 ASPM CD274 MACF1 RPL6 BRWD1 REV1	9.49e-06	1182	97	17	ctd:D014750
Drug	Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ABCA2 SYNE1 PLEKHF1 COBLL1 ADGRL1 ITGB3 SCARA3	1.90e-05	193	97	7	2764_UP
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A	EHBP1 ADGRL1 WNK1 ARHGAP6 SENP6 MFN2 PCM1	2.03e-05	195	97	7	2085_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	EHBP1 PLEKHF1 ADGRL1 ARHGAP6 USP5 MFN2 REV1	2.17e-05	197	97	7	2075_UP
Drug	Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	UBE2J1 COBLL1 MLH3 SENP6 MFN2 RIPOR1 PCM1	2.32e-05	199	97	7	6209_DN
Drug	2-Chloropyrazine [14508-49-7]; Down 200; 35uM; HL60; HT_HG-U133A	IKZF1 WNK1 USP5 VPS13D MLH3 MACF1 RIPOR1	2.32e-05	199	97	7	6148_DN
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13D	3.07e-05	3	95	2	DOID:0111611 (implicated_via_orthology)
Disease	low density lipoprotein particle size measurement	TDRD15 COBLL1 TRPS1 POLK	3.74e-05	58	95	4	EFO_0008593
Disease	Primary microcephaly	MCPH1 RBBP8 ASPM	4.76e-05	22	95	3	C0431350
Disease	Colorectal Carcinoma	POLD1 SYNE1 LAMC1 WNK1 MLH3 TRIM28 NPAP1 RPL6 ANAPC4 ZNF292	8.94e-05	702	95	10	C0009402
Disease	Cystic kidney	TMEM67 IFT80	1.53e-04	6	95	2	C0022679
Disease	beta-defensin 119 measurement	IGHV1-69 WNK1	2.84e-04	8	95	2	EFO_0801419
Disease	microcephaly (is_implicated_in)	MCPH1 ASPM	2.84e-04	8	95	2	DOID:10907 (is_implicated_in)
Disease	age at initiation of corrective lens use	ADAM11 BRWD1	2.84e-04	8	95	2	EFO_0021781
Disease	Cystic Kidney Diseases	TMEM67 IFT80	5.54e-04	11	95	2	C1691228
Disease	Charcot-Marie-Tooth disease (is_implicated_in)	NEFL MFN2	6.63e-04	12	95	2	DOID:10595 (is_implicated_in)
Disease	platelet component distribution width	SYNE1 COBLL1 PECAM1 IKZF1 WNK1 PRRC2C MACF1 POLK BRWD1	7.42e-04	755	95	9	EFO_0007984
Disease	cholesterol to total lipids in large LDL percentage	TDRD15 COBLL1 POLK	7.92e-04	56	95	3	EFO_0022235
Disease	triglycerides in IDL measurement	TDRD15 COBLL1 TRPS1	8.77e-04	58	95	3	EFO_0022149
Disease	urate measurement, spine bone mineral density	DPYS ADGRL1 C1orf141	8.77e-04	58	95	3	EFO_0004531, EFO_0007701
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	EHBP1 TDRD15 COBLL1 TRPS1 BRWD1	8.86e-04	229	95	5	EFO_0004639, EFO_0008317
Disease	bacterial pneumonia (biomarker_via_orthology)	PECAM1 ITGB3	9.10e-04	14	95	2	DOID:874 (biomarker_via_orthology)
Disease	myocardial infarction	EHBP1 TDRD15 PECAM1 LAMC1 TMEM106B UNC5C	9.56e-04	350	95	6	EFO_0000612
Disease	cholesterol to total lipids in IDL percentage	COBLL1 MACF1 POLK	9.69e-04	60	95	3	EFO_0022233
Disease	Autosomal recessive primary microcephaly	MCPH1 ASPM	1.05e-03	15	95	2	cv:C3711387
Disease	obsolete aging, cognition	TMEM106B UNC5C	1.05e-03	15	95	2	EFO_0003925, GO_0007568
Disease	bipolar I disorder	TDRD15 SYNE1 ANKHD1 TENM4	1.14e-03	141	95	4	EFO_0009963
Disease	cholesteryl esters to total lipids in medium VLDL percentage	TDRD15 COBLL1 POLK	1.17e-03	64	95	3	EFO_0022253
Disease	primary autosomal recessive microcephaly (is_implicated_in)	MCPH1 ASPM	1.20e-03	16	95	2	DOID:0070296 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, physical activity	EHBP1 TDRD15 TRPS1	1.28e-03	66	95	3	EFO_0003940, EFO_0004611
Disease	total lipids in small VLDL	TDRD15 COBLL1 TRPS1	1.33e-03	67	95	3	EFO_0022148
Disease	Charcot-Marie-Tooth disease type 2	NEFL MFN2	1.35e-03	17	95	2	cv:C0270914
Disease	very low density lipoprotein cholesterol measurement	EHBP1 TDRD15 COBLL1 TRPS1 BRWD1	1.55e-03	260	95	5	EFO_0008317
Disease	unipolar depression, bipolar disorder	SYNE1 RSRC1 TMEM106B TENM4	1.65e-03	156	95	4	EFO_0003761, MONDO_0004985
Disease	transient cerebral ischemia (biomarker_via_orthology)	WNK1 ITGB3 NEFL MFN2	1.69e-03	157	95	4	DOID:224 (biomarker_via_orthology)
Disease	Hypertriglyceridemia	TDRD15 LAMC1	1.69e-03	19	95	2	EFO_0004211
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 HYDIN	1.69e-03	19	95	2	DOID:10908 (implicated_via_orthology)
Disease	free cholesterol to total lipids in large LDL percentage	COBLL1 MACF1 POLK	1.78e-03	74	95	3	EFO_0022280
Disease	complex trait	TDRD15 RBBP8 TRPS1 VSTM2B MACF1	1.86e-03	271	95	5	EFO_0010578
Disease	Colorectal Neoplasms	POLD1 SYNE1 MLH3 TRIM28 ZNF292	2.05e-03	277	95	5	C0009404
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	TDRD15 COBLL1 TRPS1 BRWD1	2.07e-03	166	95	4	EFO_0004530, EFO_0004611
Disease	non-high density lipoprotein cholesterol measurement	EHBP1 TDRD15 COBLL1 TRPS1 LAMC1 IFT80 HYDIN BRWD1	2.15e-03	713	95	8	EFO_0005689
Disease	Autosomal Recessive Primary Microcephaly	MCPH1 ASPM	2.27e-03	22	95	2	C3711387
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TDRD15 COBLL1 TRPS1 TENM4 MACF1	2.54e-03	291	95	5	EFO_0008317, EFO_0020946
Disease	fatty acid measurement	TDRD15 COBLL1 TRPS1 MACF1 POLK BRWD1	2.89e-03	436	95	6	EFO_0005110
Disease	systemic mastocytosis	ABCA2 EYS	2.93e-03	25	95	2	MONDO_0016586

Protein segments in the cluster

Peptide	Gene	Start	Entry
VISAKVFVDRATNQS	CELF3	406	Q5SZQ8
FTSQAVDQSKVFVKV	COG7	196	P83436
FFIQTNVKNKESEST	C1orf141	101	Q5JVX7
RLTKFVQEKNTTTSV	ANAPC4	286	Q9UJX5
SQGSETSKNKFRQVT	RBBP8	506	Q99708
QSVKSRKVTTNKNAT	C2orf80	151	Q0P641
SEKRFTRKSVVASQS	BTNL8	321	Q6UX41
TRKSVVASQSFQAGK	BTNL8	326	Q6UX41
QVIAASINKESSRVF	ADGRL1	766	O94910
VFEKNVFNKTSRTES	COPZ2	76	Q9P299
RQSVVLTSNFAKSVV	ADAM11	256	O75078
TVRTKVFQSEASKVL	ADGRG7	721	Q96K78
AVVKRSQSFSKERTE	COBLL1	991	Q53SF7
NKTFSVSQKVDRVRS	ASPM	176	Q8IZT6
VSKVSFNEKAVTETS	ASPM	266	Q8IZT6
TAKRTAAVSAIATKF	CRYM	116	Q14894
TTNSKREEKLFNVTS	CD274	181	Q9NZQ7
AVTATQKKKAERFSS	GOLGA8S	186	H3BPF8
REKNSQASKVFITSD	ANAPC1	421	Q9H1A4
QNFTSESKVVFTEKT	NFATC2	601	Q13469
QKKNLQFSETSTRTG	LRRD1	81	A4D1F6
KKTRTVDITNFTAKT	MCPH1	466	Q8NEM0
FKSINTTVRVDNGQK	EYS	1956	Q5T1H1
AKSQVTTVKLTQDLF	NFRKB	981	Q6P4R8
QKFQGRVTITADKST	IGHV1-69	81	P01742
FDNLRTSKKTAESVT	EPN2	461	O95208
IIRFVTNTTKESKQD	HDHD2	41	Q9H0R4
ENRFVAVTSTNAAKI	DPYS	371	Q14117
FQSRFSVADKETKVN	FSIP2	1901	Q5CZC0
TTVTKTFKTRKASAQ	PCM1	1271	Q15154
VKRKTTAENVNTQSS	MLH3	411	Q9UHC1
VSQTQDFTKIASKSD	PECAM1	366	P16284
TKVTSSINFNKVVSV	OR6Q1	266	Q8NGQ2
SSKSDRVVASNVKVE	IKZF1	46	Q13422
VTISVDTSKNQFSLK	IGHV4-59	86	P01825
KTDKSFQGTTRQETN	MACF1	3136	Q9UPN3
QSAVKTKFEQHTVRA	MFN2	351	O95140
NTTTAKEQSIVEKFR	METTL3	251	Q86U44
FKIQVRNTVKNSSTA	GTSCR1	96	Q86UQ5
QKSSDKEFSVQSSAR	ARHGAP6	566	O43182
FTNLKDTSSKVIQSV	GAK	386	O14976
KAKQRVSYVTSTENE	DNAH6	31	Q9C0G6
RAAKFSDTIQKEVTT	HYDIN	3241	Q4G0P3
VKKQTQAESFVLTSS	IFT80	71	Q9P2H3
TKSSQSVKDVVRFFN	ABCA2	2286	Q9BZC7
ENVKISETTGNSKFR	BRWD1	2136	Q9NSI6
FSKDSTVRKTQLQSF	EHBP1	1006	Q8NDI1
VETVSEKKTFATRQV	ESCO2	246	Q56NI9
FNIDANTGTIRTTKV	CDH18	431	Q13634
VTRFNEEVKKQSVSR	ITGB3	226	P05106
VQKNATSTKAEAERT	LAMC1	1436	P11047
KSFFEAKVQAINVSS	EFHD2	191	Q96C19
NSEETQFSTRVFKKQ	CGRRF1	46	Q99675
SINKNRSVTVTSAKT	RSC1A1	466	Q92681
RTTSTKTGEAVKNIQ	SCARA3	266	Q6AZY7
TVNSSKNFTVLNFKR	RYK	176	P34925
FQSKQTGRRDTKVVS	POLD1	436	P28340
AVKSNIVTSINFSKN	LRRC40	421	Q9H9A6
DIKDANSQSVKVSFS	TMEM67	496	Q5HYA8
KKSFVVSAASATERQ	PLEKHF1	106	Q96S99
TAQVQFSKTVIGKAR	TMEM106B	166	Q9NUM4
SVRATVTQFNKVAGA	RGL2	286	O15211
VRVFTGQAKVKASAS	TRMT1	326	Q9NXH9
FQVSSKTITQRVLKF	SYT15	216	Q9BQS2
QTKEFSKRTESIAVQ	SYNE1	1381	Q8NF91
VGQKSVKVVSQSFIR	TDRD15	1251	B5MCY1
SSEAQVQKFLSRSVE	PRRC2C	866	Q9Y520
KTVESSKVSKQQQSF	PEX13	341	Q92968
NAVKTKVEAFQTTIS	PSME2	151	Q9UL46
SKTVILQSTFVSRKE	NPAP1	831	Q9NZP6
QSSDVVIVSSKYKQR	OS9	56	Q13438
VSQALFAKVAATKSQ	SATB1	511	Q01826
SATFTNVFGKKRANV	ANKHD1	1521	Q8IWZ3
VSIKDNQKDRTFTVT	CD300LB	76	A8K4G0
SRSALQEAKTEQTKT	LINC01465	116	Q8N7H1
TVSVKNNLTTKESDR	XIRP2	1911	A4UGR9
SKQEITQNKSFFSSV	XIRP2	2741	A4UGR9
TQNKSFFSSVKESQR	XIRP2	2746	A4UGR9
SKDFQKVNRSVFSGV	TRPS1	276	Q9UHF7
QKFVIATSTKIDISN	RPL6	191	Q02878
ASRKTFSNVKVSISE	SLC37A3	36	Q8NCC5
SVRDVFQVQKAKKST	REV1	851	Q9UBZ9
ESLATTETFKQQKVR	SLC27A3	626	Q5K4L6
KSVASRATVLQKTSF	RPN2	311	P04844
TNKDATKISTVRVQG	VSTM2B	91	A6NLU5
VSSKTITQRVLKFSV	SYT15B	271	X6R8R1
KNVNFEVKTRASTVS	POLK	461	Q9UBT6
NSRTTATVSQKEVEK	ZNF292	2461	O60281
RQISFKAEVNSSGKT	UBE2J1	181	Q9Y385
DSNSRRVFKIKSTVV	TENM4	1296	Q6N022
TVSFESKIQLRSKQE	SENP6	616	Q9GZR1
SIAVKAVSSNISQKD	VPS13C	1581	Q709C8
VQQTFRSSKEVKKSV	RSRC1	241	Q96IZ7
STANQSFRKVVKNTS	ROCK1	1336	Q13464
RFVTLSATNAKTNDV	WRNIP1	291	Q96S55
TKVGRFQVTTTANKV	WNK1	1941	Q9H4A3
TANKVGRFSVSKTED	WNK1	1951	Q9H4A3
STDQASAIKTKNVFI	UBR4	226	Q5T4S7
AASSVNKASTVTKRF	RIPOR1	331	Q6ZS17
AKNIVAKRKSTTATV	UNC5C	241	O95185
QAKSVAVKTTRFASF	USP5	551	P45974
QDKLFRQVTFVNSKT	ZNF300	141	Q96RE9
QKSTKEVRSSIRQVS	TRIM28	271	Q13263
SLSVKEVKSFTQIQA	VPS13D	1606	Q5THJ4
KSRFTVLTESAAKNT	NEFL	281	P07196