Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH7 CCDC88C DNAH5 DNAH6 DNAH11

4.91e-07281145GO:0051959
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 DNAH5 DNAH6 DNAH11

2.90e-06181144GO:0008569
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

ARHGEF19 ARHGEF11 ARHGEF10L CCDC88C RIC8B SBF1 KNDC1 ARHGEF26

5.46e-052311148GO:0005085
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH7 DNAH5 DNAH6 DNAH11

5.75e-05371144GO:0045505
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO5A DNAH7 MYO18B DNAH5 DNAH6 DNAH11

5.95e-051181146GO:0003774
GeneOntologyBiologicalProcesspost-Golgi vesicle-mediated transport

MON2 ANKFY1 MYO5A VPS13C SPTBN1 NBEA SEC16A DOP1A

3.66e-071191168GO:0006892
GeneOntologyBiologicalProcessGolgi vesicle transport

MON2 ANKFY1 MYO5A VPS13C SPTBN1 NBEA SEC31B ARL8B SEC16A DOP1A

2.20e-0533911610GO:0048193
GeneOntologyBiologicalProcesscytosolic transport

MON2 ANKFY1 ERC1 VPS13C VPS50 ARL8B DOP1A

2.25e-051501167GO:0016482
GeneOntologyBiologicalProcessintramanchette transport

CEP131 SPAG17

3.14e-0521162GO:1990953
GeneOntologyBiologicalProcessregulation of organelle organization

DHX36 ARHGEF19 MYO5A ERC1 VPS13C SYNE1 SPTBN1 HUWE1 TEX14 LMOD2 TERF2IP PTK2 ARHGEF10L CCDC88C PTK2B FEZ2 SEC16A CKAP2 PLEKHH2 INPP5J

5.57e-05134211620GO:0033043
GeneOntologyBiologicalProcessmicrotubule-based transport

MYO5A CCDC88C ARL8B CEP131 PRKCZ SPAG17 DNAH5 DNAH11

9.32e-052531168GO:0099111
GeneOntologyBiologicalProcessmicrotubule-based movement

MYO5A DNAH7 QRICH2 CCDC88C ARL8B CEP131 PRKCZ SPAG17 DNAH5 DNAH6 DNAH11

1.07e-0449311611GO:0007018
GeneOntologyBiologicalProcessmicrotubule-based protein transport

MYO5A CEP131 SPAG17

1.11e-04171163GO:0099118
GeneOntologyBiologicalProcessprotein transport along microtubule

MYO5A CEP131 SPAG17

1.11e-04171163GO:0098840
GeneOntologyBiologicalProcesscilium movement

DNAH7 QRICH2 CCDC88C CEP131 SPAG17 DNAH5 DNAH6 DNAH11

1.16e-042611168GO:0003341
GeneOntologyBiologicalProcessGolgi to endosome transport

MON2 VPS13C DOP1A

1.33e-04181163GO:0006895
GeneOntologyBiologicalProcessnegative regulation of organelle organization

SPTBN1 HUWE1 TEX14 LMOD2 TERF2IP CCDC88C FEZ2 CKAP2 PLEKHH2 INPP5J

1.34e-0442111610GO:0010639
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

SPTBN1 LMOD2 CCDC88C CKAP2 PLEKHH2

1.47e-04891165GO:1901880
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

SPTBN1 ETF1 LMOD2 CCDC88C CKAP2 PLEKHH2

1.65e-041441166GO:0043244
GeneOntologyBiologicalProcessmicrotubule bundle formation

DNAH7 CCDC88C LRGUK CEP131 SPAG17 DNAH5

1.71e-041451166GO:0001578
GeneOntologyBiologicalProcessintracellular transport

MON2 ANKFY1 MYO5A ERC1 VPS13C SYNE1 VPS50 SEC31B NSUN2 ERLEC1 PTK2 STK3 CCDC88C ARL8B EHD1 SEC16A CEP131 PRKCZ SPAG17 DOP1A

2.42e-04149611620GO:0046907
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

SPTBN1 LMOD2 CCDC88C CKAP2 PLEKHH2

2.54e-041001165GO:0043242
GeneOntologyBiologicalProcessregulation of protein depolymerization

SPTBN1 LMOD2 CCDC88C CKAP2 PLEKHH2

3.18e-041051165GO:1901879
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

CCDC88C SPAG17 DNAH5 DNAH11

3.41e-04591164GO:0003351
GeneOntologyBiologicalProcessaxoneme assembly

DNAH7 LRGUK CEP131 SPAG17 DNAH5

3.78e-041091165GO:0035082
GeneOntologyBiologicalProcessprotein localization to organelle

POLR1A MARK3 VPS13C SYNE1 CAMLG NBEA HUWE1 TERF2IP JAK1 STK3 ARL8B EHD1 SEC16A CEP131 PRKCZ DNAH11

4.00e-04109111616GO:0033365
GeneOntologyBiologicalProcessextracellular transport

CCDC88C SPAG17 DNAH5 DNAH11

4.12e-04621164GO:0006858
GeneOntologyCellularComponentmanchette

STRBP LRGUK CEP131 SPAG17

1.66e-05281164GO:0002177
GeneOntologyCellularComponentperinuclear region of cytoplasm

PDE4C SYNE1 VPS50 MAGEE1 PTK2 ITPR3 CCNG1 PTK2B GBP4 SBF1 EHD1 OSBPL1A SEC16A PRKCZ VDR

2.05e-0493411615GO:0048471
GeneOntologyCellularComponentdynein complex

DNAH7 DNAH5 DNAH6 DNAH11

2.30e-04541164GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH7 DNAH5 DNAH6

3.50e-04251163GO:0005858
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

4.51e-0461162GO:0097728
GeneOntologyCellularComponentcilium

PDE4C MYO5A ERC1 CCDC178 DNAH7 QRICH2 PTK2 KCTD10 EHD1 CEP131 SPAG17 DNAH5 DNAH6 DNAH11

4.55e-0489811614GO:0005929
GeneOntologyCellularComponentcytoplasmic region

ERC1 DNAH7 ARL8B PRKCZ SPAG17 DNAH5 DNAH6 DNAH11

9.05e-043601168GO:0099568
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR3 EHD1

1.07e-0391162GO:0031095
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104IPR024317
DomainDynein_HC_stalk

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104IPR024743
DomainDynein_heavy_dom-2

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104IPR013602
DomainDHC_N2

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104PF08393
DomainMT

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104PF12777
DomainAAA_8

DNAH7 DNAH5 DNAH6 DNAH11

1.09e-06141104PF12780
DomainPH_dom-like

ARHGEF19 SPTBN1 NBEA ARHGEF11 PTK2 ARHGEF10L JAK1 PTK2B SBF1 OSBPL1A WDFY3 PLEKHH2 ARHGEF26

1.34e-0642611013IPR011993
DomainDHC_fam

DNAH7 DNAH5 DNAH6 DNAH11

1.48e-06151104IPR026983
DomainDynein_heavy

DNAH7 DNAH5 DNAH6 DNAH11

1.48e-06151104PF03028
DomainDynein_heavy_dom

DNAH7 DNAH5 DNAH6 DNAH11

1.48e-06151104IPR004273
DomainFocal_adhesion_kin_target_dom

PTK2 PTK2B

3.44e-0521102IPR005189
DomainFocal_adhesion_target_reg

PTK2 PTK2B

3.44e-0521102PD006413
DomainFocal_AT

PTK2 PTK2B

3.44e-0521102PF03623
DomainP-loop_NTPase

DHX36 MYO5A ABCA13 DNAH7 LRGUK GBP4 CHST15 ARL8B ATAD3A EHD1 RAD54B MYO18B DNA2 DNAH5 DNAH6 DNAH11

3.62e-0584811016IPR027417
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH6 DNAH11

6.90e-05141103IPR011704
DomainAAA_5

DNAH5 DNAH6 DNAH11

6.90e-05141103PF07728
Domain-

DHX36 ABCA13 DNAH7 LRGUK GBP4 CHST15 ARL8B ATAD3A EHD1 RAD54B DNA2 DNAH5 DNAH6 DNAH11

1.23e-04746110143.40.50.300
DomainFERM_central

PTK2 JAK1 PTK2B PLEKHH2

1.97e-04491104IPR019748
DomainFERM_domain

PTK2 JAK1 PTK2B PLEKHH2

1.97e-04491104IPR000299
DomainAAA

ABCA13 DNAH7 ATAD3A DNAH5 DNAH6 DNAH11

2.10e-041441106SM00382
DomainAAA+_ATPase

ABCA13 DNAH7 ATAD3A DNAH5 DNAH6 DNAH11

2.10e-041441106IPR003593
DomainFERM_1

PTK2 JAK1 PTK2B PLEKHH2

2.13e-04501104PS00660
DomainFERM_2

PTK2 JAK1 PTK2B PLEKHH2

2.13e-04501104PS00661
DomainFERM_3

PTK2 JAK1 PTK2B PLEKHH2

2.13e-04501104PS50057
DomainBand_41_domain

PTK2 JAK1 PTK2B PLEKHH2

2.13e-04501104IPR019749
DomainB41

PTK2 JAK1 PTK2B PLEKHH2

2.13e-04501104SM00295
DomainDUF4704

NBEA WDFY3

3.40e-0451102IPR031570
DomainDUF4704

NBEA WDFY3

3.40e-0451102PF15787
DomainPH_BEACH

NBEA WDFY3

5.08e-0461102PF14844
DomainDH_1

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

5.19e-04631104PS00741
DomainRhoGEF

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

6.94e-04681104SM00325
DomainRhoGEF

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

7.75e-04701104PF00621
DomainDH_2

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

7.75e-04701104PS50010
Domain-

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

8.17e-047111041.20.900.10
DomainDH-domain

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

8.17e-04711104IPR000219
DomainDHC_N1

DNAH5 DNAH11

9.40e-0481102PF08385
DomainPH-BEACH_dom

NBEA WDFY3

9.40e-0481102IPR023362
Domain-

NBEA WDFY3

9.40e-04811022.30.29.40
DomainPH_BEACH

NBEA WDFY3

9.40e-0481102PS51783
DomainDynein_heavy_dom-1

DNAH5 DNAH11

9.40e-0481102IPR013594
DomainMAGE

TRO MAGEE1 MAGED4

1.04e-03341103SM01373
DomainBEACH

NBEA WDFY3

1.20e-0391102PS50197
DomainBeach

NBEA WDFY3

1.20e-0391102PF02138
Domain-

NBEA WDFY3

1.20e-03911021.10.1540.10
DomainBeach

NBEA WDFY3

1.20e-0391102SM01026
DomainBEACH_dom

NBEA WDFY3

1.20e-0391102IPR000409
DomainMAGE

TRO MAGEE1 MAGED4

1.23e-03361103PS50838
DomainMHD_dom

TRO MAGEE1 MAGED4

1.23e-03361103IPR002190
DomainMAGE

TRO MAGEE1 MAGED4

1.23e-03361103PF01454
DomainPH

ARHGEF19 SPTBN1 ARHGEF11 SBF1 OSBPL1A PLEKHH2 ARHGEF26

1.30e-032781107SM00233
DomainPH_DOMAIN

ARHGEF19 SPTBN1 ARHGEF11 SBF1 OSBPL1A PLEKHH2 ARHGEF26

1.32e-032791107PS50003
DomainPH_domain

ARHGEF19 SPTBN1 ARHGEF11 SBF1 OSBPL1A PLEKHH2 ARHGEF26

1.35e-032801107IPR001849
Domain-

ARHGEF19 SPTBN1 ARHGEF11 ARHGEF10L SBF1 OSBPL1A PLEKHH2 ARHGEF26

2.20e-0339111082.30.29.30
DomainFERM_M

PTK2 PTK2B PLEKHH2

2.51e-03461103PF00373
DomainFERM/acyl-CoA-bd_prot_3-hlx

PTK2 PTK2B PLEKHH2

3.19e-03501103IPR014352
DomainARM-type_fold

MON2 NBEA HUWE1 PAIP1 RIC8B PI4KA WDFY3

3.94e-033391107IPR016024
DomainKinase-like_dom

MARK3 TEX14 PTK2 JAK1 STK3 PTK2B PI4KA KNDC1 PRKCZ

4.74e-035421109IPR011009
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH7 DNAH5 DNAH6 DNAH11

1.53e-0527804M47755
PathwayREACTOME_INTERLEUKIN_21_SIGNALING

STAT4 JAK1 IL21

2.05e-0510803M27898
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH7 DNAH5 DNAH6 DNAH11

1.00e-0443804M47669
PathwayREACTOME_INTERLEUKIN_2_FAMILY_SIGNALING

STAT4 JAK1 PTK2B IL21

1.10e-0444804M1012
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH7 DNAH5 DNAH6 DNAH11

1.20e-0445804M47670
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

2.12e-0452804MM14743
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_ER_MEMBRANE

SBF1 PI4KA

3.15e-045802M26963
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_ER_MEMBRANE

SBF1 PI4KA

3.15e-045802MM14588
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

3.45e-0459804M11215
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKFY1 MYO5A ERC1 SYNE1 SPTBN1 ETF1 MCC NBEA HUWE1 ARHGEF11 ERBIN PTK2 CCDC88C SBF1 PI4KA CNKSR3 SEC16A CEP131 EXOG WDFY3 ARHGEF26

1.40e-119631192128671696
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DHX36 MYO5A MARK3 ERC1 SYNE1 SPTBN1 ETF1 NBEA ARHGEF11 ERBIN PTK2B EEF1G SBF1 ATAD3A PI4KA KCTD10 EHD1 SEC16A KNDC1 DNAH6 DNAH11

1.69e-0814311192137142655
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH7 DNAH5 DNAH6 DNAH11

1.27e-071411949373155
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MARK3 ERC1 SPTBN1 ERBIN DNAH7 STK3 CCDC88C PTK2B SBF1 PI4KA CNKSR3 SEC16A CEP131 CKAP2 DOP1A

2.70e-078611191536931259
Pubmed

Characterization of the piRNA complex from rat testes.

ANKFY1 STRBP SEC31B KCTD10 RAD54B WDFY3 MED7

5.67e-07140119716778019
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

MYO5A MARK3 ERC1 SPTBN1 EEF1G SBF1 ATAD3A

7.88e-07147119716959763
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

MYO5A VPS50 PAIP1 PTK2 SBF1 PI4KA AGL SEC16A

1.35e-06230119835449600
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MON2 POLR1A VPS13C CAMLG VPS50 MCC HUWE1 ERBIN PAIP1 ERLEC1 SEC16A CEP131 CKAP2

1.47e-067331191334672954
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYO5A DIS3L ERC1 SYNE1 CAMLG SPTBN1 NBEA HUWE1 SEC31B NSUN2 TERF2IP PTK2 ME3 JAK1 OSBPL1A WDFY3 CKAP2

1.87e-0612851191735914814
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SETD1A SPATA31E1 TRO MCC ANKRD62 TEX14 MAGEE1 FAM186B PAIP1 PTK2

2.41e-064301191035044719
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DHX36 SETD1A ANKFY1 POLR1A MYO5A SPTBN1 HUWE1 NSUN2 ERBIN PTK2 EEF1G SBF1 ATAD3A PI4KA EHD1 SEC16A WDFY3

3.72e-0613531191729467282
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

ANKFY1 HUWE1 JAK1 ATAD3A PI4KA

5.02e-0672119536376293
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

MARK3 SPTBN1 ERBIN SBF1 PI4KA EHD1

5.21e-06127119630442766
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

MYO5A SYNE1 SPTBN1 NBEA PTK2 PTK2B ATAD3A PI4KA

5.94e-06281119828706196
Pubmed

Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity.

STAT4 IL21

1.16e-052119223064011
Pubmed

Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.

PTK2 PTK2B

1.16e-052119215096502
Pubmed

PTK2b function during fertilization of the mouse oocyte.

PTK2 PTK2B

1.16e-052119224667605
Pubmed

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

PTK2 PTK2B

1.16e-052119218391070
Pubmed

'Psoriasis 1' reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation.

STAT4 VDR

1.16e-052119232945358
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

1.16e-052119232357925
Pubmed

Proline-rich tyrosine kinase 2 and focal adhesion kinase are involved in different phases of platelet activation by vWF.

PTK2 PTK2B

1.16e-052119211916084
Pubmed

B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.

PTK2 PTK2B

1.16e-052119219561089
Pubmed

Differential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell lines.

PTK2 PTK2B

1.16e-052119221533871
Pubmed

Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.

PTK2 PTK2B

1.16e-052119221471206
Pubmed

Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.

PTK2 PTK2B

1.16e-052119221640103
Pubmed

The FERM domain: organizing the structure and function of FAK.

PTK2 PTK2B

1.16e-052119220966971
Pubmed

Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies.

PTK2 PTK2B

1.16e-052119211420674
Pubmed

Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells.

PTK2 PTK2B

1.16e-052119229133485
Pubmed

Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair.

PTK2 PTK2B

1.16e-052119230872746
Pubmed

Non-overlapping functions for Pyk2 and FAK in osteoblasts during fluid shear stress-induced mechanotransduction.

PTK2 PTK2B

1.16e-052119221283581
Pubmed

[Rare forms of autosomal recessive spinocerebellar ataxia associated with mutations in the ANO10 (ATX-ANO10) and SYNE1 (ATX-SYNE1) genes].

SYNE1 ANO10

1.16e-052119239269294
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

1.16e-052119219410201
Pubmed

Safety, pharmacokinetic, and pharmacodynamic phase I dose-escalation trial of PF-00562271, an inhibitor of focal adhesion kinase, in advanced solid tumors.

PTK2 PTK2B

1.16e-052119222454420
Pubmed

Myosin-Va is required for preciliary vesicle transportation to the mother centriole during ciliogenesis.

MYO5A EHD1

1.16e-052119229335527
Pubmed

Pyk2 Stabilizes Striatal Medium Spiny Neuron Structure and Striatal-Dependent Action.

PTK2 PTK2B

1.16e-052119234943950
Pubmed

Protein tyrosine kinase signaling in the mouse oocyte cortex during sperm-egg interactions and anaphase resumption.

PTK2 PTK2B

1.16e-052119223401167
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 ANKFY1 MARK3 ERC1 TRO SYNE1 ERBIN CHST15 SEC16A

1.17e-05407119912693553
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

MON2 SETD1A MYO5A LAMA1 HUWE1 JAK1 MAGED4 PI4KA

1.30e-05313119838270169
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ANKFY1 ERC1 SYNE1 ERBIN RBM12 SEC16A WDFY3

1.31e-05225119712168954
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

VPS13C NBEA HUWE1 ERBIN DNAH7 EEF1G ARL8B PI4KA EHD1 SEC16A CEP131 SPTY2D1

1.52e-057771191235844135
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX36 POLR1A MYO5A STRBP SPTBN1 HUWE1 NSUN2 ITPR3 SBF1 ATAD3A SEC16A

1.59e-056531191122586326
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

SPATA31E1 CCDC88C PTK2B SBF1 GOLGA8CP SEC16A KNDC1 EXOG WDFY3

2.59e-05450119916751776
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 SETD1A ARHGEF19 HUWE1 ARHGEF11 ARHGEF10L ITPR3 CCDC88C SBF1 CHST15 PI4KA SEC16A CEP131 WDFY3

2.62e-0511051191435748872
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NBEA HUWE1 MAGEE1 ARHGEF10L DNAH5

2.63e-05101119510997877
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MON2 ERC1 TRO CEP131 DOP1A

3.02e-05104119510470851
Pubmed

Human transcription factor protein interaction networks.

DHX36 SETD1A MYO5A DIS3L STRBP SPTBN1 COP1 NSUN2 ERBIN STAT4 FHAD1 RBM12 ATAD3A SEC16A CEP131 FILIP1L

3.03e-0514291191635140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO5A ERC1 STRBP TRO SYNE1 SPTBN1 TEX14 ERBIN ERLEC1 ARL8B ATAD3A CNKSR3 SPAG17 DNAH6 CCDC158 DOP1A

3.38e-0514421191635575683
Pubmed

IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype.

STAT4 IL21

3.47e-053119217548600
Pubmed

CRISPR/Cas9 engineering of ERK5 identifies its FAK/PYK2 dependent role in adhesion-mediated cell survival.

PTK2 PTK2B

3.47e-053119230952431
Pubmed

Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines.

PTK2 PTK2B

3.47e-053119224523919
Pubmed

VDR-SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment.

PPARD VDR

3.47e-053119232900990
Pubmed

Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.

JAK1 PTK2B

3.47e-053119210702271
Pubmed

FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.

PTK2 PTK2B

3.47e-053119216202977
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAH5 DNAH6

3.47e-053119226918822
Pubmed

Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate.

PTK2 PTK2B

3.47e-053119220805505
Pubmed

Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2.

PTK2 PTK2B

3.47e-053119219661918
Pubmed

CKAP2 Promotes Ovarian Cancer Proliferation and Tumorigenesis Through the FAK-ERK Pathway.

PTK2 CKAP2

3.47e-053119228933561
Pubmed

Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.

PTK2 PTK2B

3.47e-053119225415317
Pubmed

Suppression of Pyk2 kinase and cellular activities by FIP200.

PTK2 PTK2B

3.47e-053119210769033
Pubmed

FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.

PTK2 PTK2B

3.47e-053119231110200
Pubmed

Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis.

PTK2 PTK2B

3.47e-053119217581824
Pubmed

Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.

PTK2 PTK2B

3.47e-053119218832579
Pubmed

Regulation of osteoclast structure and function by FAK family kinases.

PTK2 PTK2B

3.47e-053119222941736
Pubmed

Identification of a tissue-non-specific homologue of axonal fasciculation and elongation protein zeta-1.

FEZ2 PRKCZ

3.47e-053119214697253
Pubmed

Cooperation between c-Met and focal adhesion kinase family members in medulloblastoma and implications for therapy.

PTK2 PTK2B

3.47e-053119222188814
Pubmed

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility.

PTK2 PTK2B

3.47e-053119218195107
Pubmed

Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway.

STAT4 JAK1

3.47e-053119238429845
Pubmed

LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.

PTK2 PTK2B

3.47e-053119228699640
Pubmed

Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.

PTK2 PTK2B

3.47e-053119216760434
Pubmed

Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

MON2 DOP1A

3.47e-053119216301316
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MON2 MYO5A ERC1 CAMLG SPTBN1 NBEA HUWE1 ERBIN EEF1G ATAD3A PI4KA KCTD10 KNDC1 CEP131

3.65e-0511391191436417873
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

DHX36 ANKFY1 MARK3 TEX14

3.88e-0555119418570454
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

MON2 DHX36 GCDH HUWE1 STK3 MAGED4 PI4KA AGL CNKSR3 DNA2

4.65e-056061191036538041
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

DHX36 MARK3 STRBP GCDH HUWE1 NSUN2 EEF1G ATAD3A DNA2

4.69e-05486119930940648
Pubmed

Proteomic profiling of Myc-associated proteins.

ERC1 SEC31B ERBIN EEF1G KNDC1

4.70e-05114119521150319
Pubmed

USP7 controls NGN3 stability and pancreatic endocrine lineage development.

SPTBN1 HUWE1 NSUN2 ATAD3A

4.79e-0558119437117185
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

POLR1A MYO5A MARK3 VPS13C HUWE1 ERBIN TERF2IP PTK2 INTS6 RIC8B ATAD3A KNDC1 PRKCZ CKAP2 ARHGEF26 DOP1A

4.95e-0514891191628611215
Pubmed

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.

MYO5A NSUN2 PRKCZ

4.97e-0521119325340873
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MON2 MYO5A ERC1 SPTBN1 NBEA HUWE1 ERBIN ITPR3 SBF1 PI4KA SEC16A CEP131 CKAP2

6.48e-0510491191327880917
Pubmed

Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.

PTK2 PTK2B

6.93e-054119211668182
Pubmed

Control of mitochondrial homeostasis by endocytic regulatory proteins.

ANKFY1 EHD1

6.93e-054119228596240
Pubmed

EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.

ANKFY1 EHD1

6.93e-054119227189942
Pubmed

SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling.

ERC1 CEP131

6.93e-054119227224062
Pubmed

FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation.

PTK2 PTK2B

6.93e-054119211787067
Pubmed

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis.

STAT4 IL21

6.93e-054119219404967
Pubmed

The human peroxisome proliferator-activated receptor delta gene is a primary target of 1alpha,25-dihydroxyvitamin D3 and its nuclear receptor.

PPARD VDR

6.93e-054119215890193
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

6.93e-054119218492703
Pubmed

Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins.

PTK2 PTK2B

6.93e-054119210980697
Pubmed

Dot far-western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins.

PTK2 PTK2B

6.93e-05411929750131
Pubmed

Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.

PTK2 PTK2B

6.93e-054119219880522
Pubmed

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.

PTK2 PTK2B

6.93e-054119219435801
Pubmed

Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions.

PTK2 PTK2B

6.93e-05411929422762
Pubmed

v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts.

PTK2 PTK2B

6.93e-054119214500722
Pubmed

Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.

PTK2 PTK2B

6.93e-054119225889845
Pubmed

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion.

PTK2 PTK2B

6.93e-05411929442086
Pubmed

Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

PTK2 PTK2B

6.93e-054119212794117
Pubmed

Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast.

PTK2 PTK2B

6.93e-054119212674328
Pubmed

FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.

PTK2 PTK2B

6.93e-054119226274564
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

MARK3 SPTBN1 JAK1 EEF1G ATAD3A SEC16A PRKCZ ARHGEF26

7.50e-05401119825852190
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

ABCA13 LAMA1 CCDC88C EEF1G DNAH5 DOP1A

8.43e-05208119633230847
InteractionATG5 interactions

MYO5A VPS13C VPS50 PAIP1 PTK2 JAK1 SBF1 PI4KA AGL SEC16A WDFY3

4.11e-0634411411int:ATG5
InteractionFLT1 interactions

MON2 DHX36 STRBP ETF1 NSUN2 PTK2 PTK2B PI4KA

8.18e-061791148int:FLT1
InteractionDLGAP1 interactions

MYO5A SYNE1 SPTBN1 NBEA HUWE1 ERBIN PTK2 CNKSR3

8.52e-061801148int:DLGAP1
InteractionRHOA interactions

ARHGEF19 MARK3 STRBP VPS13C CAMLG SPTBN1 ETF1 GCDH ARHGEF11 ERBIN ITPR3 JAK1 CCDC88C SBF1 ARL8B ATAD3A PI4KA LRRC8A PRKCZ ARHGEF26

1.19e-05119911420int:RHOA
InteractionRAB11A interactions

MON2 MYO5A MARK3 VPS13C CAMLG SPTBN1 VPS50 NBEA NSUN2 ERBIN ITPR3 PI4KA EHD1 SEC16A WDFY3 DOP1A

1.75e-0583011416int:RAB11A
InteractionYWHAG interactions

MARK3 ERC1 SPTBN1 MCC HUWE1 ERBIN DNAH7 PTK2 STK3 CCDC88C EEF1G SBF1 ARL8B PI4KA CNKSR3 SEC16A CEP131 PRKCZ CKAP2 DOP1A

2.13e-05124811420int:YWHAG
InteractionAGAP2 interactions

MYO5A TRO SYNE1 SPTBN1 MCC NBEA PTK2 PTK2B

2.60e-052101148int:AGAP2
InteractionPFN1 interactions

MON2 ANKFY1 MYO5A ERC1 VPS13C SPTBN1 NBEA ARHGEF11 EEF1G SEC16A CEP131 PRKCZ

3.16e-0550911412int:PFN1
InteractionRHOJ interactions

MARK3 VPS13C SPTBN1 ETF1 GCDH ERBIN JAK1 SBF1 ARL8B ATAD3A PI4KA EHD1 LRRC8A

6.06e-0563311413int:RHOJ
InteractionRHOB interactions

MARK3 SPTBN1 NBEA ARHGEF11 ERBIN JAK1 CCDC88C SBF1 ARL8B ATAD3A PI4KA KCTD10 EHD1 LRRC8A ARHGEF26

7.82e-0584011415int:RHOB
GeneFamilyDyneins, axonemal

DNAH7 DNAH5 DNAH6 DNAH11

5.29e-0717724536
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTK2 JAK1 PTK2B PLEKHH2

4.64e-05507241293
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF19 ARHGEF11 ARHGEF10L ARHGEF26

1.38e-0466724722
GeneFamilyMAGE family

TRO MAGEE1 MAGED4

5.38e-04407231136
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA WDFY3

5.53e-0497221230
GeneFamilyEF-hand domain containing

MCC CRACR2B SCGN DNAH7 EHD1

1.80e-03219725863
CoexpressionGAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS

ABCA13 SYNE1 NBEA ARHGEF11 DNAH7 CCDC88C FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.46e-0745911713M39136
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

ABCA13 DNAH7 ANKRD18B FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.30e-053171179M40298
CoexpressionGSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN

PDE4C SYNE1 ETF1 ITPR3 RAD54B CKAP2 FILIP1L

3.01e-051971177M3193
CoexpressionGSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN

MON2 ARHGEF19 LAMA1 TERF2IP PTK2B PI4KA IL21

3.31e-052001177M6372
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYNE1 NBEA DNAH7 ANKRD18B FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.20e-12194117114a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

STRBP SYNE1 SPTBN1 AGR3 NBEA DNAH7 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.44e-1219511711fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

STRBP SYNE1 SPTBN1 AGR3 NBEA DNAH7 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.44e-1219511711eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

ABCA13 SYNE1 SPTBN1 AGR3 DNAH7 PTK2 CNKSR3 SPAG17 DNAH5 DNAH6 DNAH11

4.69e-1219611711af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

ABCA13 SYNE1 SPTBN1 AGR3 DNAH7 PTK2 CNKSR3 SPAG17 DNAH5 DNAH6 DNAH11

4.69e-12196117116d02d494196e3f857d53eea46d9419690d43beca
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NBEA DNAH7 CCDC88C FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

7.01e-10169117914aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 SERPINA12 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

1.06e-0917711793cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 SERPINA12 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

1.06e-09177117912a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.56e-0918511795e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.71e-09187117904dba2ed09ee4180830bdf0191921696697ea234
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.71e-091871179805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

1.88e-091891179a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellCiliated-cil-3|World / Class top

SYNE1 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.16e-0919211794989ebb8812b8af1870599acd932849122c05a29
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 DNAH7 ANKRD18B FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.26e-091931179ea345d34440b25f65358a53dc72831998d1c3620
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCA13 DNAH7 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.36e-091941179756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 AGR3 NBEA DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

2.47e-091951179649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 AGR3 NBEA DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

2.47e-091951179129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 AGR3 NBEA DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

2.47e-0919511793e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 AGR3 NBEA DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

2.47e-0919511799651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SYNE1 AGR3 DNAH7 ANKRD18B FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

3.09e-0920011796a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AGR3 DNAH7 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

3.09e-09200117931d75c26055177d656df1fbb10b764cebd61e122
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AGR3 DNAH7 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

3.09e-092001179e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

7.80e-0915411784e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

7.80e-0915411787556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.22e-081761178ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.53e-081791178d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

2.53e-0817911788a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 DNAH11

2.53e-0817911785e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

2.64e-081801178cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 STRBP DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

2.64e-0818011781f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

2.88e-081821178fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 DNAH11

3.55e-0818711781bba994aaaa9825b54aaeaff3829850267bc4602
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 DNAH11

3.55e-081871178d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

3.86e-081891178057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

3.86e-0818911789f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

3.86e-081891178fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

ABCA13 DNAH7 LRGUK SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

3.86e-08189117827329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

3.86e-0818911783e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

3.86e-081891178e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

4.02e-0819011789ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 FHAD1 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

4.02e-0819011783ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SYNE1 CCDC178 DNAH7 ITPR3 PLEKHH2 SPAG17 DNAH5

4.02e-0819011783fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-0819111787b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-0819111789621e22e14ea069f22713947c9faa2d882abe5fe
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-0819111782a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-08191117846c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ABCA13 AGR3 DNAH7 KNDC1 SPAG17 DNAH5 CCDC33 DNAH11

4.18e-081911178ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-0819111782d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.18e-081911178e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.18e-0819111789d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ABCA13 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 CCDC33 DNAH11

4.18e-081911178e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class （2021.01.30）

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-081911178cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGR3 LRGUK KNDC1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.18e-0819111786a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ABCA13 AGR3 DNAH7 KNDC1 SPAG17 DNAH5 CCDC33 DNAH11

4.18e-0819111786228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.18e-0819111781c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

4.36e-08192117803acd4a26b986e34eee608747347791122f1aa52
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ABCA13 NBEA DNAH7 FHAD1 KNDC1 SPAG17 DNAH5 DNAH11

4.36e-0819211789cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

4.36e-08192117831c6046589e2fbb0486fd044c5b128099d37872f
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ABCA13 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.53e-0819311780e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SYNE1 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.53e-081931178ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

4.53e-081931178bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCA13 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

4.53e-081931178a0baa8be6f590b2031fede22be588715ae458e93
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ABCA13 AGR3 DNAH7 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

4.72e-081941178958e648138676d46698090b4046cb484083ae449
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.72e-081941178b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.72e-08194117843be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.91e-081951178cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell18-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

4.91e-0819511783441381759cd00d125752401dc99b78be1c78f88
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

4.91e-08195117834e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.11e-081961178a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.11e-081961178a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.11e-081961178009e83c7251cf300be78b263634d233a8d972a68
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.11e-08196117889ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.11e-081961178d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

SYNE1 AGR3 FHAD1 KNDC1 SPAG17 DNAH5 DNAH6 CCDC33

5.31e-081971178fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYNE1 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-08197117891637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYNE1 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-08197117822c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 DNAH11

5.31e-08197117874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYNE1 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-0819711783bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-081971178e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYNE1 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-08197117887db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

ABCA13 AGR3 DNAH7 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.31e-08197117818fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 DNAH11

5.31e-081971178d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

AGR3 CRACR2B DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33

5.52e-081981178e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellwk_20-22-Epithelial-Proximal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.52e-08198117816c54b884500066ade05a406915f9569ca8abdfc
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

AGR3 CRACR2B DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33

5.52e-081981178e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.74e-081991178b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

AGR3 DNAH7 FHAD1 LRGUK SPAG17 DNAH5 DNAH6 CCDC33

5.74e-08199117815f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AGR3 CRACR2B DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33

5.97e-082001178da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AGR3 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-0820011787cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-082001178f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA13 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-082001178d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-082001178ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ABCA13 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-082001178a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 DNAH7 FHAD1 SPAG17 DNAH5 DNAH6 CCDC33 DNAH11

5.97e-082001178918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
Diseasehepatocellular carcinoma (is_implicated_in)

CYP2C19 STAT4 JAK1 CCNG1 IL21 VDR

7.56e-051811146DOID:684 (is_implicated_in)
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

8.83e-0541142DOID:0050144 (is_implicated_in)
Diseasesquamous cell carcinoma

MARK3 ERBIN SEC16A DNAH11

1.34e-04671144EFO_0000707
Diseaseresponse to bevacizumab, Proteinuria

JAK1 DNAH5

1.47e-0451142EFO_0005943, HP_0000093
Diseasejuvenile idiopathic arthritis

ABCA13 SCGN STAT4 IL21

1.97e-04741144EFO_0002609
Diseasevisceral heterotaxy (implicated_via_orthology)

OSBPL1A DNAH5 DNAH11

3.97e-04371143DOID:0050545 (implicated_via_orthology)
Diseasevolumetric bone mineral density

SPTBN1 PTK2B FHAD1

5.78e-04421143EFO_0007620
Diseasenephritis (implicated_via_orthology)

PTK2 PTK2B

6.52e-04101142DOID:10952 (implicated_via_orthology)
Diseaseprimary biliary cholangitis (is_implicated_in)

STAT4 VDR

6.52e-04101142DOID:12236 (is_implicated_in)
DiseaseWeight Gain

SPTBN1 PPARD FEZ2 DNAH11

6.71e-041021144C0043094
Diseaseautoimmune hepatitis (is_implicated_in)

STAT4 VDR

1.12e-03131142DOID:2048 (is_implicated_in)
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

1.31e-03141142DOID:0050144 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

SERPINA12 STAT4 ITPR3 STK3 SEC16A

1.51e-032151145DOID:9970 (implicated_via_orthology)
Diseaseage-related hearing impairment

SPTBN1 PTK2 CCNG1 KCTD10 CNKSR3 SPAG17

1.65e-033241146EFO_0005782
DiseaseBrugada syndrome

EXOG MYO18B

2.42e-03191142MONDO_0015263
Diseaseurate measurement, bone density

ERC1 SYNE1 MCC ERBIN CCNG1 GBP4 SEC16A DNAH11

2.82e-036191148EFO_0003923, EFO_0004531
DiseaseBronchiectasis

DNAH5 DNAH11

3.25e-03221142C0006267
Diseaseplatelet reactivity measurement, response to clopidogrel

CYP2C19 CCNG1

3.55e-03231142EFO_0004985, GO_1903493
DiseaseGraves disease

SETD1A STAT4 ITPR3

3.85e-03811143EFO_0004237

Protein segments in the cluster

PeptideGeneStartEntry
AKMIQKLADLRSLNE

VDR

381

P11473
LSRFEEAMKLRKQLI

CAMLG

156

P49069
LQILMEFLKVARRNK

COP1

261

Q8NHY2
LGNMLAKNLLFEKER

ERLEC1

151

Q96DZ1
DMQKLKVINLSDNRL

ERBIN

366

Q96RT1
NMLKNIELFDKLSLR

KCTD10

181

Q9H3F6
KSKERRVFLLNDMLV

ARHGEF10L

556

Q9HCE6
TFLGLLIMENRLKKE

ATP13A5

686

Q4VNC0
LLSELDMKKLRDRVQ

CCDC33

696

Q8N5R6
LIENMKKALRLIQSE

AGR3

151

Q8TD06
QLEQQSKLKMRLEAL

ATAD3A

86

Q9NVI7
LILKENLNMRKISAK

GVQW3

106

Q3ZCU0
KITLKDFLQAMNDIR

SPATA5

596

Q8NB90
QLTLKLNRLKDMELA

ARHGEF11

1431

O15085
LNTDQLKMDILFKKL

ANKRD18B

741

A2A2Z9
LLAVNRKKEQMVAFL

ANKRD62

176

A6NC57
SQMAFQILLRKKEID

DNAH11

3786

Q96DT5
LEEVFLMLLQDSNKK

ABCA13

4151

Q86UQ4
LEQRAMLLKRLAFAI

DOP1A

2171

Q5JWR5
LSLEILIRMFKNSKE

ARHGEF26

456

Q96DR7
DLLLMKQALEFQLKK

FAM186B

306

Q8IYM0
KLEMESKLHRNLLFQ

CKAP2

546

Q8WWK9
LEKIDMIRKRLQNFS

RBM12

511

Q9NTZ6
EMLLRSLDQIKNIKF

RAD54B

411

Q9Y620
ALRLRLEEKETMLNK

ERC1

526

Q8IUD2
LEKIQFLLAQMVKRT

QRICH2

1061

Q9H0J4
SRFKKRMLIEQLENF

INTS6

856

Q9UL03
LKKQILRTDNISFML

JAK1

526

P23458
EIRILQDKLNSTMKL

ITPR3

2621

Q14573
SLKKMANLTELELIR

LRRC8A

586

Q8IWT6
ELRNVLLNNSEKMKV

NSUN2

566

Q08J23
FVLKDMKLLRQSLAT

ANO10

421

Q9NW15
AKMAELQVRDLSLKL

ARHGEF19

646

Q8IW93
AVNLLDRFLSKMKVQ

CCNG1

76

P51959
KQLIEKMNLSAIQDR

ARL8B

141

Q9NVJ2
TELMKLANRFQLQLL

ANKFY1

136

Q9P2R3
MNIDAKILNKILANR

nan

536

O00370
TLLQERANKLVKYLM

MAGED4

411

Q96JG8
ESKARKLVQLFLLMD

MAGEE1

746

Q9HCI5
KELRKLNMSILINFL

MED7

76

O43513
MEIVKLLKENTTLLR

LMOD2

316

Q6P5Q4
SLNRQLESELQMLKK

CCDC88C

991

Q9P219
DQTLEILKNKFITMR

CCDC178

686

Q5BJE1
EMASNKFKRILNREL

PDE4C

231

Q08493
RQDMLALQIIDLFKN

PI4KA

1856

P42356
KNEQLRLLKILDMAS

GBP4

601

Q96PP9
SVLRLEKIMENLKNA

EXOG

321

Q9Y2C4
FMLLRLTELDQKKIK

LRGUK

351

Q96M69
KKLLENMQSDLRALS

MON2

11

Q7Z3U7
QRLDREISNFLKMIK

OSBPL1A

371

Q9BXW6
REQLKMLLLAVLNFT

HUWE1

86

Q7Z6Z7
ELKFLRQENRKNMLL

CCDC167

66

Q9P0B6
ASKIRELLAEKMQQL

PLEKHH2

31

Q8IVE3
DVKQMLLKLVELRSS

PAIP1

361

Q9H074
LKMQDKELRAVFLRL

SBF1

361

O95248
KMLVVLRNSELFQAL

PROX2

511

Q3B8N5
LKNDRAAVKLTMLEL

MCC

576

P23508
INLYLSMLSEKRKQI

DNAH6

2671

Q9C0G6
QLKTIEEKILRMLFT

DNAH6

3231

Q9C0G6
RMQELESLLAQQKKA

FHAD1

711

B1AJZ9
NKLLKNLAFMESDIL

CYP2C19

231

P33261
LARNQLIQKKLADML

GCDH

326

Q92947
NMLKNRLQSLEAIEK

FILIP1L

586

Q4L180
ELQDLKESMKLALRQ

GALNT8

66

Q9NY28
KDLLNFRSDLKVILM

DHX36

351

Q9H2U1
MLQKREKVLLLRTFQ

DIS3L

1

Q8TF46
IDRMLERLKKSNELL

DNAH7

1036

Q8WXX0
NMQKEKVSLLRQLEL

CRACR2B

326

Q8N4Y2
FLERFKSLLQKMIHQ

IL21

136

Q9HBE4
TRNDLLIICKKFNLM

C6orf50

16

Q9HD87
SLQKLFREVRIMKIL

MARK3

96

P27448
KYIILMTLQDRNEKL

ME3

106

Q16798
LKGQLEEMKSRVQFL

KNDC1

1171

Q76NI1
LITGMFQRLDKLRKN

EEF1G

341

P26641
MEVQRLEALLKALKS

CCDC158

426

Q5M9N0
LNKDLAELINKMRLA

PTK2B

946

Q14289
KRELLKLRNQMAFSL

DNA2

351

P51530
LMENTFVSKKLRDLI

DNA2

581

P51530
LRKMQELLQTQDFSK

EHD1

356

Q9H4M9
RILALQENFLLQFKM

SCGN

176

O76038
EEKKQAMLLLQRALA

CEP131

581

Q9UPN4
MLKNRELLKIFEQAS

LINC00597

1

Q9H2U6
NQALRMLKKFERLNI

DNAH5

566

Q8TE73
LQILTKILRAMKEDS

FEZ2

321

Q9UHY8
VLIRKLLALMAQEQK

POLR1A

336

O95602
LLDRMFLVAKIQANV

TEX47

46

Q8TBZ9
MNLQDIRYILKNDLK

TEX14

501

Q8IWB6
FPKLLQKMADLRQLV

PPARD

396

Q03181
EKRLSQIQDILLMKG

SYNE1

2661

Q8NF91
DLIKSMLRNELQFKE

NBPF12

336

Q5TAG4
KDLLKSMLRNELQFK

NBPF12

606

Q5TAG4
KENMQILLRLAKLNE

RIC8B

86

Q9NVN3
AKNLLDVIDQARLKM

PTK2

1031

Q05397
IQANLLFDRLKPLKM

LAMA1

2076

P25391
RAFMLLFLKQLILKD

NBEA

681

Q8NFP9
VQKLLETLIAKRALM

SPATA31E1

361

Q6ZUB1
NLRKILDSKAIDLMN

STRBP

376

Q96SI9
VTLEQDSRMKFLKLL

SEC31B

471

Q9NQW1
PMNFTDLLRLAEKKQ

SPTY2D1

166

Q68D10
AIMDSDLLKLNQLKF

SETD1A

1551

O15047
KIKDRTLFVDQNLSM

SPAG17

666

Q6Q759
ELLMRLKDNRDLQKF

SPTBN1

1266

Q01082
KELARQNMDLGFKLL

SERPINA12

46

Q8IW75
NKILFRVDSKQMNLL

CHST15

41

Q7LFX5
LETDNMKNLVLKLRA

CNK3/IPCEF1

76

G9CGD6
LETDNMKNLVLKLRA

CNKSR3

76

Q6P9H4
VNSMLNKRLKDALFT

INPP5J

466

Q15735
FQQFLMKLEKLTDIR

VPS50

881

Q96JG6
LQFRMKIINLKLERF

SCN2B

81

O60939
KNLSLEELQMRLKAL

STK3

441

Q13188
NAKLMREFQLIPKLL

WDFY3

1536

Q8IZQ1
LNNRLIKLSQDFMIL

NHLRC3

186

Q5JS37
MASQLRLFDPQLKEK

SEC16A

1851

O15027
MFRVNLKEIDKQSSL

TRO

496

Q12816
KRIFILLEELQGSMK

SAGE2P

551

A6NJ88
LLEELQGSMKVKRQF

SAGE2P

556

A6NJ88
ILIMGNSKLREAFLK

TAS2R9

281

Q9NYW1
LTLQEMLNSLDFKRK

STAT4

196

Q14765
DLAQKSFRLLMDINL

VPS13C

1746

Q709C8
RQFQVLDAPLLKKLM

MYO18B

1271

Q8IUG5
KNLLNSKNIMLIDVR

TSTD3

36

H0UI37
KIIRQLMEKFNLDLS

TERF2IP

316

Q9NYB0
MFDQRLQSKVLKLVD

ETF1

241

P62495
LLNEMEKLEKTLFRL

AGL

11

P35573
KLEQSMREQALLKAQ

GOLGA8CP

201

A6NN73
MREQALLKAQLTQLK

GOLGA8CP

206

A6NN73
VLLVRLKKNDQIYAM

PRKCZ

266

Q05513
DMSLFLKLQKRVTEL

MYO5A

1151

Q9Y4I1