Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	gated channel activity	CACNA1B CACNA1D CACNA1S TRPV1 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A	4.88e-08	334	112	13	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1B CACNA1D CACNA1S TRPV1 TMEM63B GRIK2 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	6.66e-08	343	112	13	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1B CACNA1D CACNA1S TRPV1 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	2.91e-07	459	112	14	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 GRIK2 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	3.40e-07	465	112	14	GO:0046873
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 TMEM63B GRIK2 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	4.29e-07	627	112	16	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 TMEM63B GRIK2 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	9.16e-07	664	112	16	GO:0008324
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1B CACNA1D CACNA1S TRPV1 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11	9.57e-07	184	112	9	GO:0022832
GeneOntologyMolecularFunction	channel activity	CACNA1B CACNA1D CACNA1S TRPV1 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.44e-06	525	112	14	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.47e-06	526	112	14	GO:0022803
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	2.01e-06	793	112	17	GO:0015075
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1B CACNA1D CACNA1S TRPV1 KCNG3 KCNJ5 KCNJ8 KCNJ11	2.28e-06	152	112	8	GO:0022843
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 TMEM63B GRIK2 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	5.04e-06	758	112	16	GO:0015318
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1B CACNA1D CACNA1S TRPV1 KCNG3 KCNJ5 KCNJ8 KCNJ11	8.66e-06	182	112	8	GO:0005244
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TRPV1 TMEM63B GRIK2 TPCN1 KCNJ5 KCNJ8 KCNJ11	1.41e-05	140	112	7	GO:0099094
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SLC2A14 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A ABCC12	2.91e-05	1180	112	19	GO:0022857
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1B CACNA1D CACNA1S	5.98e-05	14	112	3	GO:0008331
GeneOntologyMolecularFunction	transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SLC2A14 TMEM63B GRIK2 TMC4 KCNG3 TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A ABCC12	9.54e-05	1289	112	19	GO:0005215
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TRPV1 TMEM63B GRIK2 TPCN1 KCNJ5 KCNJ8 KCNJ11	1.09e-04	193	112	7	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	TRPV1 TMEM63B GRIK2 TPCN1 KCNJ5 KCNJ8 KCNJ11	1.24e-04	197	112	7	GO:0022834
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1B CACNA1D CACNA1S TRPV1	1.28e-04	46	112	4	GO:0005245
GeneOntologyMolecularFunction	sodium channel activity	GRIK2 TPCN1 SCN7A SCN9A	2.06e-04	52	112	4	GO:0005272
GeneOntologyMolecularFunction	osmolarity-sensing monoatomic cation channel activity	TMEM63B SCN7A	3.08e-04	5	112	2	GO:1990760
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	TPCN1 SCN7A SCN9A	4.07e-04	26	112	3	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	IMPA1 KCNJ11 SCN9A	4.07e-04	26	112	3	GO:0031420
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC4A7 SLC4A8 GRIK2 TPCN1 SCN7A SCN9A	4.09e-04	171	112	6	GO:0015081
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A8	4.61e-04	6	112	2	GO:0008510
GeneOntologyMolecularFunction	ATP-activated inward rectifier potassium channel activity	KCNJ8 KCNJ11	4.61e-04	6	112	2	GO:0015272
GeneOntologyMolecularFunction	osmosensor activity	TMEM63B SCN7A	4.61e-04	6	112	2	GO:0005034
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNJ5 KCNJ8 KCNJ11	5.08e-04	28	112	3	GO:0005242
GeneOntologyMolecularFunction	potassium channel activity	GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11	7.76e-04	128	112	5	GO:0005267
GeneOntologyMolecularFunction	calcium channel activity	CACNA1B CACNA1D CACNA1S TRPV1 TPCN1	8.04e-04	129	112	5	GO:0005262
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1B CACNA1D	1.09e-03	9	112	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1B CACNA1D	1.09e-03	9	112	2	GO:0099626
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1B CACNA1D CACNA1S TRPV1 TPCN1	1.62e-03	151	112	5	GO:0015085
GeneOntologyMolecularFunction	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	KCNJ5 KCNJ8	1.98e-03	12	112	2	GO:1902282
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A7 SLC4A8	2.34e-03	13	112	2	GO:0140410
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11	2.52e-03	167	112	5	GO:0015079
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNG3 KCNJ5 KCNJ8 KCNJ11	2.61e-03	102	112	4	GO:0005249
GeneOntologyMolecularFunction	endopeptidase activity	PRSS54 PAPPA2 SPG7 RHBDL1 ADAM10 CAPN13 ACE2 RHBDL3	2.93e-03	430	112	8	GO:0004175
GeneOntologyMolecularFunction	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	KCNJ5 KCNJ8	3.12e-03	15	112	2	GO:0086008
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNJ8 KCNJ11	4.01e-03	17	112	2	GO:0099508
GeneOntologyMolecularFunction	monooxygenase activity	NLRP11 CYP4B1 AGMO NOS2	4.02e-03	115	112	4	GO:0004497
GeneOntologyMolecularFunction	ligand-gated sodium channel activity	GRIK2 TPCN1	4.50e-03	18	112	2	GO:0015280
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	TRPV1 TPCN1	4.50e-03	18	112	2	GO:0015278
GeneOntologyMolecularFunction	mechanosensitive monoatomic ion channel activity	TMEM63B TMC4	4.50e-03	18	112	2	GO:0008381
GeneOntologyBiologicalProcess	heart contraction	CACNA1B CACNA1D TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A	5.26e-06	298	112	10	GO:0060047
GeneOntologyBiologicalProcess	heart process	CACNA1B CACNA1D TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A	7.24e-06	309	112	10	GO:0003015
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 TMEM63B GRIK2 TMC4 KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	8.41e-06	1115	112	19	GO:0034220
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	CACNA1B CACNA1D CACNA1S TRPV1 KCNJ5 KCNJ8 KCNJ11	1.25e-05	142	112	7	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	CACNA1B CACNA1D CACNA1S TRPV1 KCNJ5 KCNJ8 KCNJ11	1.25e-05	142	112	7	GO:0098659
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 TMEM63B KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.28e-05	942	112	17	GO:0098655
GeneOntologyBiologicalProcess	action potential	CACNA1D GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.41e-05	201	112	8	GO:0001508
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	CACNA1D KCNJ5 KCNJ8 SCN7A SCN9A	2.18e-05	62	112	5	GO:0086002
GeneOntologyBiologicalProcess	striated muscle contraction	CACNA1D CACNA1S ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A	2.46e-05	217	112	8	GO:0006941
GeneOntologyBiologicalProcess	cardiac muscle contraction	CACNA1D ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A	3.57e-05	167	112	7	GO:0060048
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1B CACNA1D CACNA1S TRPV1 ACE2 KCNJ5 KCNJ8 KCNJ11	3.72e-05	230	112	8	GO:0098739
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	3.79e-05	922	112	16	GO:0098662
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 TMEM63B GRIK2 TMC4 KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A CCL8	4.62e-05	1374	112	20	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 TMEM63B KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A CCL8	4.98e-05	1157	112	18	GO:0006812
GeneOntologyBiologicalProcess	regulation of heart contraction	CACNA1B CACNA1D TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 PDE5A	6.51e-05	249	112	8	GO:0008016
GeneOntologyBiologicalProcess	muscle contraction	CACNA1D CACNA1S TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A	6.56e-05	400	112	10	GO:0006936
GeneOntologyBiologicalProcess	metal ion transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 KCNG3 EDNRA TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A CCL8	9.88e-05	1000	112	16	GO:0030001
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	CACNA1D KCNJ5 KCNJ8 SCN7A SCN9A	1.12e-04	87	112	5	GO:0086001
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 SPG7 KCNG3 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.20e-04	1017	112	16	GO:0098660
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1B CACNA1D CACNA1S TRPV1	1.33e-04	48	112	4	GO:0098703
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	CACNA1D EDNRA NF1 NOS2	1.33e-04	48	112	4	GO:0031281
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1B CACNA1D CACNA1S TRPV1	1.33e-04	48	112	4	GO:1902656
GeneOntologyBiologicalProcess	positive regulation of lyase activity	CACNA1D EDNRA NF1 NOS2	1.45e-04	49	112	4	GO:0051349
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	CACNA1D KCNJ5 KCNJ8 SCN7A SCN9A	1.53e-04	93	112	5	GO:0086003
GeneOntologyBiologicalProcess	response to resveratrol	KCNJ8 KCNJ11	1.74e-04	4	112	2	GO:1904638
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	CACNA1D OR4N4 TCP11 CCR9 OR8S1 TAAR3P SSTR1 PTGIR PTH OR13J1 ADCY9 EDNRA GRK1 GNRHR2 PDE5A CCL8 CCL15 NOS2 HCRTR1	1.75e-04	1395	112	19	GO:0007186
GeneOntologyBiologicalProcess	muscle system process	CACNA1D CACNA1S TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A ASB2	1.93e-04	547	112	11	GO:0003012
GeneOntologyBiologicalProcess	regulation of membrane potential	CACNA1D TRPV1 SLC4A8 CKAP5 GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	2.33e-04	559	112	11	GO:0042391
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	CACNA1D CACNA1S SLC4A7 SLC4A8 STXBP4 GRIK2 PTH EDNRA RPTOR KCNJ11 SCN7A CCL8 CCL15 HCRTR1	2.51e-04	866	112	14	GO:0055082
GeneOntologyBiologicalProcess	cellular homeostasis	CACNA1D CACNA1S SLC4A7 SLC4A8 STXBP4 GRIK2 PTH EDNRA RPTOR KCNJ11 SCN7A CCL8 CCL15 NOS2 HCRTR1	2.71e-04	981	112	15	GO:0019725
GeneOntologyBiologicalProcess	detection of temperature stimulus involved in thermoception	TRPV1 GRIK2	2.89e-04	5	112	2	GO:0050960
GeneOntologyBiologicalProcess	regulation of blood circulation	CACNA1B CACNA1D TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 PDE5A	4.09e-04	326	112	8	GO:1903522
GeneOntologyBiologicalProcess	regulation of cyclase activity	CACNA1D EDNRA NF1 NOS2	5.43e-04	69	112	4	GO:0031279
GeneOntologyBiologicalProcess	detection of temperature stimulus involved in sensory perception	TRPV1 GRIK2 SCN9A	5.69e-04	30	112	3	GO:0050961
GeneOntologyBiologicalProcess	circulatory system process	CACNA1B CACNA1D TRPV1 SLC4A8 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A NOS2	6.36e-04	733	112	12	GO:0003013
GeneOntologyBiologicalProcess	actin-mediated cell contraction	CACNA1D KCNJ5 KCNJ8 SCN7A SCN9A	6.48e-04	127	112	5	GO:0070252
GeneOntologyBiologicalProcess	regulation of lyase activity	CACNA1D EDNRA NF1 NOS2	6.72e-04	73	112	4	GO:0051339
GeneOntologyBiologicalProcess	regulation of presynaptic membrane potential	GRIK2 KCNJ8 KCNJ11	6.89e-04	32	112	3	GO:0099505
GeneOntologyBiologicalProcess	regulation of heart rate	CACNA1D TRPV1 EDNRA KCNJ5 KCNJ8	6.96e-04	129	112	5	GO:0002027
GeneOntologyBiologicalProcess	detection of temperature stimulus	TRPV1 GRIK2 SCN9A	7.55e-04	33	112	3	GO:0016048
GeneOntologyBiologicalProcess	peripheral nervous system axon ensheathment	SIRT2 NF1 ARHGEF10	7.55e-04	33	112	3	GO:0032292
GeneOntologyBiologicalProcess	myelination in peripheral nervous system	SIRT2 NF1 ARHGEF10	7.55e-04	33	112	3	GO:0022011
GeneOntologyBiologicalProcess	blood circulation	CACNA1B CACNA1D TRPV1 EDNRA ACE2 KCNJ5 KCNJ8 SCN7A SCN9A PDE5A NOS2	8.03e-04	648	112	11	GO:0008015
GeneOntologyCellularComponent	cation channel complex	CACNA1B CACNA1D CACNA1S GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	6.01e-07	235	113	10	GO:0034703
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1B CACNA1D CACNA1S GRIK2 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	6.54e-06	378	113	11	GO:0034702
GeneOntologyCellularComponent	septin complex	SEPTIN8 SEPTIN14 SEPTIN10	5.36e-05	14	113	3	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN8 SEPTIN14 SEPTIN10	5.36e-05	14	113	3	GO:0005940
GeneOntologyCellularComponent	T-tubule	CACNA1D CACNA1S EDNRA KCNJ5 KCNJ11	6.92e-05	79	113	5	GO:0030315
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN8 SEPTIN14 SEPTIN10	8.18e-05	16	113	3	GO:0032156
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A8 IMPA1 CKAP5 PSMC2 GRIK2 WLS ADAM10 ADCY9 SIRT2 NF1 RPTOR SEPTIN14 KCNJ11 WDFY3	1.01e-04	1228	113	18	GO:0036477
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1B CACNA1D CACNA1S GRIK2 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.26e-04	523	113	11	GO:1902495
GeneOntologyCellularComponent	inward rectifying potassium channel	KCNJ8 KCNJ11	1.73e-04	4	113	2	GO:0008282
GeneOntologyCellularComponent	transporter complex	CACNA1B CACNA1D CACNA1S GRIK2 KCNG3 TPCN1 KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	1.95e-04	550	113	11	GO:1990351
GeneOntologyCellularComponent	dendrite	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A8 CKAP5 PSMC2 GRIK2 WLS ADAM10 ADCY9 NF1 RPTOR SEPTIN14	2.19e-04	858	113	14	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1B CACNA1D CACNA1S TRPV1 SLC4A8 CKAP5 PSMC2 GRIK2 WLS ADAM10 ADCY9 NF1 RPTOR SEPTIN14	2.24e-04	860	113	14	GO:0097447
GeneOntologyCellularComponent	potassium channel complex	GRIK2 KCNG3 KCNJ5 KCNJ8 KCNJ11	2.54e-04	104	113	5	GO:0034705
GeneOntologyCellularComponent	axon	CACNA1B SLC4A8 IMPA1 SPG7 GRIK2 ADAM10 ADCY9 SEPTIN8 SIRT2 NF1 SEPTIN14 KCNJ11 SCN9A WDFY3	3.21e-04	891	113	14	GO:0030424
GeneOntologyCellularComponent	sodium channel complex	GRIK2 SCN7A SCN9A	5.07e-04	29	113	3	GO:0034706
GeneOntologyCellularComponent	neuronal cell body	CACNA1B CACNA1D TRPV1 SLC4A8 IMPA1 CKAP5 GRIK2 ADAM10 SIRT2 RPTOR SEPTIN14 KCNJ11 WDFY3	5.79e-04	835	113	13	GO:0043025
GeneOntologyCellularComponent	sarcolemma	CACNA1D CACNA1S EDNRA KCNJ5 KCNJ8 KCNJ11	5.88e-04	190	113	6	GO:0042383
GeneOntologyCellularComponent	neuron projection membrane	CACNA1D TRPV1 WLS KCNJ11	1.02e-03	82	113	4	GO:0032589
GeneOntologyCellularComponent	perikaryon	CACNA1D CKAP5 GRIK2 SIRT2 SEPTIN14 WDFY3	1.35e-03	223	113	6	GO:0043204
GeneOntologyCellularComponent	cell body	CACNA1B CACNA1D TRPV1 SLC4A8 IMPA1 CKAP5 GRIK2 ADAM10 SIRT2 RPTOR SEPTIN14 KCNJ11 WDFY3	1.53e-03	929	113	13	GO:0044297
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1D CACNA1S	1.85e-03	12	113	2	GO:1990454
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1B CACNA1D CACNA1S	1.97e-03	46	113	3	GO:0005891
GeneOntologyCellularComponent	glial cell projection	SLC4A8 SIRT2 SCN7A	2.10e-03	47	113	3	GO:0097386
GeneOntologyCellularComponent	neuron projection cytoplasm	SPG7 CKAP5 GRIK2 WLS	3.01e-03	110	113	4	GO:0120111
GeneOntologyCellularComponent	dendrite membrane	CACNA1D TRPV1 WLS	3.46e-03	56	113	3	GO:0032590
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN7A SCN9A	3.74e-03	17	113	2	GO:0001518
MousePheno	increased chemical nociceptive threshold	CACNA1B TRPV1 PTGIR SCN9A	3.39e-05	30	87	4	MP:0008531
MousePheno	abnormal nervous system electrophysiology	CACNA1B CACNA1D TRPV1 SLC2A14 GRIK2 SSTR1 SEPTIN8 KCNJ11 SCN9A NOS2	3.65e-05	329	87	10	MP:0002272
MousePheno	wide lambdoid suture	IBSP EDNRA	3.83e-05	2	87	2	MP:0030357
MousePheno	wide coronal suture	IBSP EDNRA	3.83e-05	2	87	2	MP:0030351
Domain	Channel_four-helix_dom	CACNA1B CACNA1D CACNA1S KCNG3 TPCN1 SCN7A SCN9A	5.07e-08	57	113	7	IPR027359
Domain	-	CACNA1B CACNA1D CACNA1S KCNG3 TPCN1 SCN7A SCN9A	5.07e-08	57	113	7	1.20.120.350
Domain	Ion_trans_dom	CACNA1B CACNA1D CACNA1S TRPV1 KCNG3 TPCN1 SCN7A SCN9A	4.52e-07	114	113	8	IPR005821
Domain	Ion_trans	CACNA1B CACNA1D CACNA1S TRPV1 KCNG3 TPCN1 SCN7A SCN9A	4.52e-07	114	113	8	PF00520
Domain	VDCC_a1su_IQ	CACNA1B CACNA1D CACNA1S	7.42e-06	7	113	3	IPR014873
Domain	GPHH	CACNA1B CACNA1D CACNA1S	7.42e-06	7	113	3	PF16905
Domain	GPHH_dom	CACNA1B CACNA1D CACNA1S	7.42e-06	7	113	3	IPR031649
Domain	Ca_chan_IQ	CACNA1B CACNA1D CACNA1S	7.42e-06	7	113	3	SM01062
Domain	Ca_chan_IQ	CACNA1B CACNA1D CACNA1S	7.42e-06	7	113	3	PF08763
Domain	EF-hand-dom_pair	CACNA1B CACNA1S STXBP4 RHBDL1 FLG2 TPCN1 CAPN13 RHBDL3 SCN7A SCN9A	9.68e-06	287	113	10	IPR011992
Domain	VDCCAlpha1	CACNA1B CACNA1D CACNA1S	2.51e-05	10	113	3	IPR002077
Domain	Septin	SEPTIN8 SEPTIN14 SEPTIN10	5.90e-05	13	113	3	PF00735
Domain	G_SEPTIN_dom	SEPTIN8 SEPTIN14 SEPTIN10	5.90e-05	13	113	3	IPR030379
Domain	G_SEPTIN	SEPTIN8 SEPTIN14 SEPTIN10	5.90e-05	13	113	3	PS51719
Domain	Septin	SEPTIN8 SEPTIN14 SEPTIN10	7.48e-05	14	113	3	IPR016491
Domain	Peptidase_S54_rhomboid_met	RHBDL1 RHBDL3	1.08e-04	3	113	2	IPR017213
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ5 KCNJ8 KCNJ11	1.14e-04	16	113	3	IPR013518
Domain	IRK	KCNJ5 KCNJ8 KCNJ11	1.14e-04	16	113	3	PF01007
Domain	-	KCNJ5 KCNJ8 KCNJ11	1.14e-04	16	113	3	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ5 KCNJ8 KCNJ11	1.14e-04	16	113	3	IPR016449
Domain	VDCC_L_a1su	CACNA1D CACNA1S	2.16e-04	4	113	2	IPR005446
Domain	DUF4704	NBEAL2 WDFY3	3.59e-04	5	113	2	IPR031570
Domain	DUF4704	NBEAL2 WDFY3	3.59e-04	5	113	2	PF15787
Domain	PH_BEACH	NBEAL2 WDFY3	5.36e-04	6	113	2	PF14844
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A8	7.47e-04	7	113	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A8	7.47e-04	7	113	2	PS00219
Domain	GAF	PDE6A PDE5A	7.47e-04	7	113	2	PF01590
Domain	PH-BEACH_dom	NBEAL2 WDFY3	9.92e-04	8	113	2	IPR023362
Domain	Peptidase_S54_rhomboid	RHBDL1 RHBDL3	9.92e-04	8	113	2	IPR002610
Domain	-	NBEAL2 WDFY3	9.92e-04	8	113	2	2.30.29.40
Domain	PH_BEACH	NBEAL2 WDFY3	9.92e-04	8	113	2	PS51783
Domain	GAF	PDE6A PDE5A	9.92e-04	8	113	2	IPR003018
Domain	GAF	PDE6A PDE5A	9.92e-04	8	113	2	SM00065
Domain	ARM-type_fold	CKAP5 RALGAPA2 PPP2R5E NF1 RPTOR NBEAL2 ULK4 WDFY3	1.06e-03	339	113	8	IPR016024
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A8	1.27e-03	9	113	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A8	1.27e-03	9	113	2	PF07565
Domain	BEACH_dom	NBEAL2 WDFY3	1.27e-03	9	113	2	IPR000409
Domain	Rhomboid	RHBDL1 RHBDL3	1.27e-03	9	113	2	PF01694
Domain	-	SLC4A7 SLC4A8	1.27e-03	9	113	2	3.40.1100.10
Domain	Peptidase_S54_rhomboid_dom	RHBDL1 RHBDL3	1.27e-03	9	113	2	IPR022764
Domain	GAF_dom-like	PDE6A PDE5A	1.27e-03	9	113	2	IPR029016
Domain	BEACH	NBEAL2 WDFY3	1.27e-03	9	113	2	PS50197
Domain	Beach	NBEAL2 WDFY3	1.27e-03	9	113	2	PF02138
Domain	-	NBEAL2 WDFY3	1.27e-03	9	113	2	1.10.1540.10
Domain	-	PDE6A PDE5A	1.27e-03	9	113	2	3.30.450.40
Domain	-	RHBDL1 RHBDL3	1.27e-03	9	113	2	1.20.1540.10
Domain	Beach	NBEAL2 WDFY3	1.27e-03	9	113	2	SM01026
Domain	ARM-like	CKAP5 PPP2R5E NF1 RPTOR NBEAL2 ULK4 WDFY3	1.28e-03	270	113	7	IPR011989
Domain	Na_channel_asu	SCN7A SCN9A	1.58e-03	10	113	2	IPR001696
Domain	Leu-rich_rpt_4	LRRIQ3 LRR1	1.58e-03	10	113	2	IPR025875
Domain	HCO3_cotransp	SLC4A7 SLC4A8	1.58e-03	10	113	2	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A8	1.58e-03	10	113	2	IPR011531
Domain	LRR_4	LRRIQ3 LRR1	1.58e-03	10	113	2	PF12799
Domain	Na_trans_assoc	SCN7A SCN9A	1.58e-03	10	113	2	IPR010526
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A8	1.58e-03	10	113	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A8	1.58e-03	10	113	2	IPR003020
Domain	Na_trans_assoc	SCN7A SCN9A	1.58e-03	10	113	2	PF06512
Domain	-	CKAP5 PPP2R5E NF1 RPTOR ULK4 WDFY3	2.32e-03	222	113	6	1.25.10.10
Domain	PDEase	PDE6A PDE5A	5.80e-03	19	113	2	IPR023088
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1B CACNA1D CACNA1S	3.89e-06	6	83	3	M47762
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1B CACNA1D CACNA1S KCNJ5 KCNJ8 KCNJ11 SCN7A SCN9A	2.35e-08	139	116	8	16985003
Pubmed	Androglobin, a chimeric mammalian globin, is required for male fertility.	SEPTIN8 SEPTIN14 SEPTIN10 NOS2	4.38e-07	19	116	4	35700329
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1B CACNA1D CACNA1S	2.00e-06	8	116	3	28330839
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RNF223 SPG7 KAT2A RALGAPA2 ADCY9 TPCN1 PCNX2 SIRT2 TRAPPC12 FANCI RPTOR NBEAL2 KCNJ11 ULK4 WDFY3	4.25e-06	1105	116	15	35748872
Pubmed	ATP-sensitive K+ channels in pig urethral smooth muscle cells are heteromultimers of Kir6.1 and Kir6.2.	KCNJ8 KCNJ11	1.10e-05	2	116	2	18945825
Pubmed	Expression of ATP-sensitive potassium channels in human pregnant myometrium.	KCNJ8 KCNJ11	1.10e-05	2	116	2	21418633
Pubmed	Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.	KCNJ8 KCNJ11	1.10e-05	2	116	2	16501027
Pubmed	PDE-5 and NOS II mRNA expression in menopausal women: a molecular biology study.	PDE5A NOS2	1.10e-05	2	116	2	20177899
Pubmed	Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.	CACNA1D KCNJ11	1.10e-05	2	116	2	11424233
Pubmed	Kir6.2-containing ATP-sensitive K(+) channel is required for cardioprotection of resveratrol in mice.	KCNJ8 KCNJ11	1.10e-05	2	116	2	24498880
Pubmed	Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice.	KCNJ8 KCNJ11	1.10e-05	2	116	2	34715352
Pubmed	Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.	CACNA1D KCNJ5	1.10e-05	2	116	2	24866132
Pubmed	Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.	CACNA1D CACNA1S	1.10e-05	2	116	2	28978442
Pubmed	KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease-related pathology.	KCNJ8 KCNJ11	1.10e-05	2	116	2	37129980
Pubmed	Disruption of Kir6.2-containing ATP-sensitive potassium channels impairs maintenance of hypoxic gasping in mice.	KCNJ8 KCNJ11	1.10e-05	2	116	2	17445233
Pubmed	N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1+/- mice.	CACNA1B NF1	1.10e-05	2	116	2	24755485
Pubmed	Cellular and Genetic Causes of Idiopathic Hyperaldosteronism.	CACNA1D KCNJ5	1.10e-05	2	116	2	30354720
Pubmed	Kir6.1 Heterozygous Mice Exhibit Aberrant Amygdala-Dependent Cued Fear Memory.	KCNJ8 KCNJ11	1.10e-05	2	116	2	31808063
Pubmed	Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.	CACNA1D KCNJ5	1.10e-05	2	116	2	35779252
Pubmed	[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].	CACNA1D CACNA1S	1.10e-05	2	116	2	21789999
Pubmed	Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex.	CACNA1S RPTOR	1.10e-05	2	116	2	25431931
Pubmed	Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury.	CACNA1D KCNJ5	1.10e-05	2	116	2	37593151
Pubmed	Prostacyclin enhances the expression of LPS/INF-gamma-induced nitric oxide synthase in human monocytes.	PTGIR NOS2	1.10e-05	2	116	2	12119468
Pubmed	Molecular and functional characterization of the endothelial ATP-sensitive potassium channel.	KCNJ8 KCNJ11	1.10e-05	2	116	2	28893911
Pubmed	Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson's disease.	KCNJ8 KCNJ11	1.10e-05	2	116	2	29540778
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1B CACNA1D CACNA1S	1.60e-05	15	116	3	20188150
Pubmed	International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.	KCNJ5 KCNJ8 KCNJ11	1.60e-05	15	116	3	16382105
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1B CACNA1D CACNA1S	1.60e-05	15	116	3	24453333
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN8 SEPTIN14 SEPTIN10	1.96e-05	16	116	3	22575789
Pubmed	Aldosterone-Producing Adenomas: Histopathology-Genotype Correlation and Identification of a Novel CACNA1D Mutation.	CACNA1D KCNJ5	3.30e-05	3	116	2	28584016
Pubmed	NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone.	CACNA1D KCNJ5	3.30e-05	3	116	2	28584012
Pubmed	Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system.	KCNJ8 KCNJ11	3.30e-05	3	116	2	21984445
Pubmed	Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.	KCNJ8 KCNJ11	3.30e-05	3	116	2	10559219
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1D CACNA1S	3.30e-05	3	116	2	17767505
Pubmed	Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.	SLC4A7 SLC4A8	3.30e-05	3	116	2	14736710
Pubmed	Mammalian septins nomenclature.	SEPTIN8 SEPTIN10	3.30e-05	3	116	2	12475938
Pubmed	A mechanism for ATP-sensitive potassium channel diversity: Functional coassembly of two pore-forming subunits.	KCNJ8 KCNJ11	3.30e-05	3	116	2	11136227
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1D CACNA1S	3.30e-05	3	116	2	2173707
Pubmed	FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7.	TRPV1 SCN9A	3.30e-05	3	116	2	28162808
Pubmed	The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes.	TRPV1 SCN9A	3.30e-05	3	116	2	31285762
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1D KCNJ5	3.30e-05	3	116	2	26831068
Pubmed	Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry.	KCNJ5 KCNJ11	3.30e-05	3	116	2	31909710
Pubmed	Molecular basis and characteristics of KATP channel in human corporal smooth muscle cells.	KCNJ8 KCNJ11	3.30e-05	3	116	2	12934053
Pubmed	Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1.	KCNJ8 KCNJ11	3.30e-05	3	116	2	19139106
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1D CACNA1S	3.30e-05	3	116	2	17289261
Pubmed	Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activity.	KCNJ8 KCNJ11	3.30e-05	3	116	2	18001767
Pubmed	Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.	KCNJ8 KCNJ11	3.30e-05	3	116	2	9130167
Pubmed	Expression of functional Kir6.1 channels regulates glutamate release at CA3 synapses in generation of epileptic form of seizures.	KCNJ8 KCNJ11	3.30e-05	3	116	2	17883401
Pubmed	Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated CaV2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin.	CACNA1B TRPV1	3.30e-05	3	116	2	34353899
Pubmed	Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function.	PDE5A NOS2	3.30e-05	3	116	2	17101732
Pubmed	The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.	SLC4A7 SLC4A8	3.30e-05	3	116	2	12444018
Pubmed	And-1 is required for the stability of histone acetyltransferase Gcn5.	KAT2A WDHD1	3.30e-05	3	116	2	21725360
Pubmed	Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation.	TRPV1 SCN7A	3.30e-05	3	116	2	27252474
Pubmed	Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.	PTGIR ACE2 NOS2	3.37e-05	19	116	3	21052031
Pubmed	Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.	CCL8 CCL15 NOS2	3.37e-05	19	116	3	10438970
Pubmed	The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice.	TCP11 CYP4B1 RHBDL3	4.60e-05	21	116	3	17032746
Pubmed	Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.	CACNA1D SLC4A7 ULK4	4.60e-05	21	116	3	25249183
Pubmed	Rare independent mutations in renal salt handling genes contribute to blood pressure variation.	KCNJ5 KCNJ8 KCNJ11	5.32e-05	22	116	3	18391953
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	CCR9 TAAR3P SSTR1 PTGIR PTH GNRHR2	5.89e-05	200	116	6	18240029
Pubmed	cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G.	PTH LMO1	6.59e-05	4	116	2	9027506
Pubmed	Assembly limits the pharmacological complexity of ATP-sensitive potassium channels.	KCNJ8 KCNJ11	6.59e-05	4	116	2	11825905
Pubmed	Evolution and diversity of mammalian sodium channel genes.	SCN7A SCN9A	6.59e-05	4	116	2	10198179
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1D CACNA1S	6.59e-05	4	116	2	20937870
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	NF1 SCN9A	6.59e-05	4	116	2	22260870
Pubmed	Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium.	KCNJ8 KCNJ11	6.59e-05	4	116	2	12356945
Pubmed	The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.	SLC4A7 SLC4A8	6.59e-05	4	116	2	12403779
Pubmed	Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma.	CACNA1D KCNJ5	6.59e-05	4	116	2	26351028
Pubmed	Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart.	KCNJ8 KCNJ11	6.59e-05	4	116	2	16085792
Pubmed	Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.	SLC4A7 SLC4A8	6.59e-05	4	116	2	17715183
Pubmed	Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.	ACE2 NOS2	6.59e-05	4	116	2	16574921
Pubmed	Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin.	CACNA1B TRPV1	6.59e-05	4	116	2	38643253
Pubmed	Identification of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6.	PDE6A PDE5A	6.59e-05	4	116	2	23033484
Pubmed	TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.	RPTOR NOS2	6.59e-05	4	116	2	24562310
Pubmed	Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.	KCNJ8 KCNJ11	6.59e-05	4	116	2	28842488
Pubmed	Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.	CACNA1D CACNA1S GRIK2 SSTR1	7.66e-05	67	116	4	16987237
Pubmed	Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene.	SLC2A14 PTH LMO1	7.88e-05	25	116	3	8617496
Pubmed	Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.	KCNJ5 KCNJ11	1.10e-04	5	116	2	28464250
Pubmed	Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1.	PTH LMO1	1.10e-04	5	116	2	10321731
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1B CACNA1D	1.10e-04	5	116	2	11296258
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A7 SLC4A8	1.10e-04	5	116	2	23500099
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1B CACNA1D	1.10e-04	5	116	2	15451373
Pubmed	Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells.	PTGIR NOS2	1.10e-04	5	116	2	18930709
Pubmed	Acute stimulation of glucose influx upon mitoenergetic dysfunction requires LKB1, AMPK, Sirt2 and mTOR-RAPTOR.	SIRT2 RPTOR	1.10e-04	5	116	2	27793977
Pubmed	Structure and chromosomal mapping of the TNF-alpha inducible endothelial protein 1 (Edp1) gene in the mouse.	NF1 NOS2	1.10e-04	5	116	2	9804998
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CKAP5 PSMC2 ELP1 AAR2 SLC25A3 PPP2R5E GLG1 FANCI RPTOR	1.13e-04	560	116	9	35241646
Pubmed	Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse.	CACNA1B CACNA1D	1.64e-04	6	116	2	16029198
Pubmed	The rhomboid-like superfamily: molecular mechanisms and biological roles.	RHBDL1 RHBDL3	1.64e-04	6	116	2	25062361
Pubmed	The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.	KAT2A WDHD1	1.64e-04	6	116	2	21987584
Pubmed	mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts.	IBSP RPTOR	1.64e-04	6	116	2	26090674
Pubmed	Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.	KAT2A SIRT2	1.64e-04	6	116	2	12887892
Pubmed	The rhomboid protease family: a decade of progress on function and mechanism.	RHBDL1 RHBDL3	1.64e-04	6	116	2	22035660
Pubmed	Sampling the membrane: function of rhomboid-family proteins.	RHBDL1 RHBDL3	1.64e-04	6	116	2	23369641
Pubmed	Emerging role of rhomboid family proteins in mammalian biology and disease.	RHBDL1 RHBDL3	1.64e-04	6	116	2	23562403
Pubmed	Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene.	AMBN IBSP	1.64e-04	6	116	2	8626794
Pubmed	Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.	AMBN CACNA1B IBSP	1.67e-04	32	116	3	19320717
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CACNA1B CACNA1D CACNA1S	1.83e-04	33	116	3	22357600
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	KCNJ5 KCNJ8 KCNJ11	2.01e-04	34	116	3	26378152
Pubmed	MEPE Localization in the Craniofacial Complex and Function in Tooth Dentin Formation.	AMBN IBSP	2.29e-04	7	116	2	26927967
Pubmed	Novel Role for Claudin-11 in the Regulation of Osteoblasts via Modulation of ADAM10-Mediated Notch Signaling.	IBSP ADAM10	2.29e-04	7	116	2	31112308
Pubmed	Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.	CACNA1B LRRIQ3	2.29e-04	7	116	2	21057379
Cytoband	17q11.2	NF1 RHBDL3 CCL8 CCL15	1.82e-04	110	116	4	17q11.2
GeneFamily	Septins	SEPTIN8 SEPTIN14 SEPTIN10	2.49e-05	13	82	3	732
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ5 KCNJ8 KCNJ11	4.83e-05	16	82	3	276
GeneFamily	Calcium voltage-gated channel subunits	CACNA1B CACNA1D CACNA1S	2.17e-04	26	82	3	253
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL2 WDFY3	7.17e-04	9	82	2	1230
GeneFamily	Rhomboid family	RHBDL1 RHBDL3	1.78e-03	14	82	2	926
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	AMBN CYP4B1 TMEM63B GRIK2 ITLN2 NBEAL2 MSLN	4.03e-07	179	114	7	d5763912a4ce7188535675e338799b856edb9dda
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 CYP4B1 EDNRA KCNJ8 KCNJ11 PDE5A MSLN	6.93e-07	194	114	7	52ecec2618c3bb5fdd7fb06b5a40bd6f0aedfe1d
ToppCell	normal_Lung-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	SLC4A7 TMEM176A WLS TPCN1 KCNJ5 SCN9A CCL8	7.95e-07	198	114	7	fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CYP4B1 FANCD2OS PTGIR EDNRA ACE2 KCNJ8	8.91e-07	126	114	6	2b06adfb00a557bd90ad93719548a49f9ae9edeb
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CYP4B1 FANCD2OS PTGIR EDNRA ACE2 KCNJ8	8.91e-07	126	114	6	43e7b226a195ab2068518b3a9ffd2192129e8ae4
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PAPPA2 PTGIR EDNRA ACE2 PDE5A ASB2	1.87e-06	143	114	6	9bfb3674c8f011b9cf928b522777b8d54478db8d
ToppCell	Substantia_nigra-Endothelial-MURAL\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA KLHL31 ACE2 PDE5A ASB2	4.74e-06	168	114	6	271a81c59a9a75bac6107c68fead03e7f35bc192
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA KLHL31 ACE2 PDE5A ASB2	4.74e-06	168	114	6	b220e732eb7b204fc263a9f2e8ddae6bf9fa98f4
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 PDE5A ASB2	5.60e-06	173	114	6	51328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCell	Globus_pallidus-Endothelial-MURAL\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 PDE5A ASB2	5.60e-06	173	114	6	b77cd5dbda3a206922f20224f4e10a3bf712f7db
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D SLC4A7 KCNJ5 ULK4 AFF1 PDE5A	5.79e-06	174	114	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH1 SCN7A ULK4 PDE5A SNORC	6.39e-06	177	114	6	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STXBP4 PTGIR EDNRA KCNJ8 AGMO PDE5A	6.81e-06	179	114	6	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 KAT2A AAR2 ARHGEF10 KCNJ11 NOL8	7.03e-06	180	114	6	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 RHBDL1 EDNRA KCNJ8 PDE5A ASB2	8.74e-06	187	114	6	accb8a78b885703a27d4b560f0053f03d82ff3af
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA SEPTIN8 ACE2 KCNJ8 PDE5A	9.29e-06	189	114	6	de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 CYP4B1 PTGIR EDNRA KCNJ8 PDE5A	1.02e-05	192	114	6	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 EDNRA KCNJ8 PDE5A ASB2 HCRTR1	1.02e-05	192	114	6	a804cb101c3a5585f72217e1143584b1ca436724
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK2 RUNX1T1 WLS EDNRA KCNJ5 SCN9A	1.02e-05	192	114	6	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A ASB2	1.05e-05	193	114	6	1043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A ASB2	1.05e-05	193	114	6	0266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1D RUNX1T1 PTGIR EDNRA SCN7A PDE5A	1.11e-05	195	114	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	(3)_MNP-(3)_Macrophage_MARCOneg\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC4A7 TMEM176A WLS TPCN1 SCN9A CCL8	1.11e-05	195	114	6	e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA KCNJ8 PDE5A ASB2 MSLN	1.11e-05	195	114	6	0bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell	AT1\|World / shred by cell class for parenchyma	CYP4B1 TMEM63B ITLN2 FANCI NBEAL2 MSLN	1.14e-05	196	114	6	2bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	CACNA1D TMEM176A PTGIR EDNRA SCN7A PDE5A	1.18e-05	197	114	6	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	CACNA1D SLC4A7 SUSD3 TMC4 TTC7B ARHGEF10	1.21e-05	198	114	6	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1D TMEM176A PTGIR EDNRA SCN7A PDE5A	1.21e-05	198	114	6	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACNA1D TMEM176A PTGIR EDNRA SCN7A GASK1A	1.25e-05	199	114	6	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RNF223 CYP4B1 TMC4 CAPN13 NOS2 MSLN	1.25e-05	199	114	6	7223f853335492ca617dbec3e4b6872a8a463a45
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACNA1D TMEM176A PTGIR EDNRA SCN7A PDE5A	1.25e-05	199	114	6	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACNA1D TMEM176A PTGIR EDNRA SCN7A GASK1A	1.28e-05	200	114	6	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1D TMEM176A PTGIR EDNRA SCN7A PDE5A	1.28e-05	200	114	6	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1D RUNX1T1 PTGIR EDNRA SCN7A PDE5A	1.28e-05	200	114	6	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CYP4B1 PTGIR EDNRA ACE2 KCNJ8	1.83e-05	126	114	5	b0bc61be1d4ce8114077c524fedfdf89128bcf12
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	SLC4A7 SSTR1 LMO1 RHBDL3 ASB2	2.29e-05	132	114	5	a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CYP4B1 FANCD2OS EDNRA ACE2 KCNJ8	2.55e-05	135	114	5	e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	LRRIQ3 RHBDL1 ADCY9 PCNX2 MSLN	5.09e-05	156	114	5	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	LRRIQ3 RHBDL1 ADCY9 PCNX2 MSLN	5.09e-05	156	114	5	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP4B1 RHBDL1 KLHL31 CAPN13 RHBDL3	5.25e-05	157	114	5	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	Hippocampus-Endothelial-MURAL\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 ASB2	5.41e-05	158	114	5	2d73b5e59c650c603fec6223b1c51f0962f7bc81
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AMBN CACNA1B CYP4B1 GRK1 NOS2	5.41e-05	158	114	5	78b48b110b777bcc4c07cd23388bee911c0231d6
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 ASB2	5.41e-05	158	114	5	7f4a644534b78f7e7539cae1fd895dad6f96862b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 EDNRA KCNJ8 RHBDL3 PDE5A	5.57e-05	159	114	5	cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 EDNRA KCNJ8 RHBDL3 PDE5A	5.57e-05	159	114	5	a75ab494959575143cefdaec99e7aee3f318d559
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-Treg\|ICU-NoSEP / Disease, Lineage and Cell Type	SLC4A7 SUSD3 TMC4 TTC7B ARHGEF10	5.57e-05	159	114	5	d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHBDL1 ITLN2 GRK1 SNORC NOS2	5.74e-05	160	114	5	6005948e400e781cdb876ba350b3ec8991e3945f
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	AMBN CYP4B1 GRIK2 ITLN2 NBEAL2	5.74e-05	160	114	5	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	Club-club-13\|World / Class top	SLC4A7 CYP4B1 HID1 ACE2 MSLN	6.09e-05	162	114	5	7d18f05a65ac715e62d610df9cc4a26539340dee
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE6A TRIM10 CCL8 MSLN	7.07e-05	86	114	4	1f44bb41835445aa60a2e3c31616c5847447a246
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 DNAH1 TMEM232 ULK4 WDR17	7.43e-05	169	114	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRSS54 CYP4B1 CAPN13 NOS2 MSLN	7.86e-05	171	114	5	25c1979e972c959e1ce4c57804f976f53a247ad7
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Goblet\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRSS54 CYP4B1 CAPN13 NOS2 MSLN	7.86e-05	171	114	5	fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCell	Club-club-3\|World / Class top	CYP4B1 HID1 CAPN13 ACE2 MSLN	8.08e-05	172	114	5	34fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S TMEM176A HID1 TRIM10 GASK1A	8.30e-05	173	114	5	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	facs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S LRRIQ3 TMEM176A HID1 ARHGEF10	8.53e-05	174	114	5	3b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 TMEM63B CAPN13 ACE2 MSLN	8.53e-05	174	114	5	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 TMEM63B CAPN13 ACE2 MSLN	8.53e-05	174	114	5	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP4B1 ITLN2 TRIM10 CAPN13 SNORC	9.24e-05	177	114	5	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRPV1 PDE6A RUNX1T1 ARHGEF10 GASK1A	9.49e-05	178	114	5	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRPV1 PDE6A RUNX1T1 ARHGEF10 GASK1A	9.49e-05	178	114	5	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH1 SCN7A ULK4 SNORC	9.49e-05	178	114	5	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D SLC4A7 ULK4 AFF1 PDE5A	9.49e-05	178	114	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM176A ADCY9 RHBDL3 PDE5A ASB2	9.49e-05	178	114	5	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH1 SCN7A ULK4 SNORC	9.49e-05	178	114	5	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 HID1 RINT1 ARHGEF10 TMEM44	9.75e-05	179	114	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR9 FANCD2OS LRR1 WDHD1 SCN7A	1.00e-04	180	114	5	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S SLC4A8 TMEM176A TRIM10 ASB2	1.00e-04	180	114	5	54e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S SLC4A8 TMEM176A TRIM10 ASB2	1.00e-04	180	114	5	bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1D RUNX1T1 EDNRA SCN7A PDE5A	1.03e-04	181	114	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPY19L2 SUSD3 WLS SCN9A IGSF1	1.05e-04	182	114	5	6e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 ASB2	1.05e-04	182	114	5	da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCell	Cerebellum-Endothelial-MURAL\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PTGIR EDNRA ACE2 KCNJ8 ASB2	1.05e-04	182	114	5	b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPY19L2 SUSD3 WLS SCN9A IGSF1	1.05e-04	182	114	5	cd972d30519db706477c6b0c901165b81b74abed
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC4A7 SLC4A8 STXBP4 LMO1	1.08e-04	183	114	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	droplet-Marrow-nan-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 CCR9 TMEM176A CCL8 ASB2	1.08e-04	183	114	5	b5782b18decfe85026acf42daac0670d92385861
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.08e-04	183	114	5	0f02136359787bd78146617990968baa47a65d86
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDL1 KLHL31 ACE2 KCNJ8 ASB2	1.08e-04	183	114	5	6f5dbac2748f50105f0f548d189c42ef14287019
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 CCR9 TMEM176A CCL8 ASB2	1.08e-04	183	114	5	e32847cfebba7c8bb2026e33c3c85f64819460a9
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.08e-04	183	114	5	2f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY9 EDNRA ACE2 PDE5A ASB2	1.11e-04	184	114	5	89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.11e-04	184	114	5	9c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCell	facs-Heart-RV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.11e-04	184	114	5	31dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY9 EDNRA ACE2 PDE5A ASB2	1.11e-04	184	114	5	34c84ac9a32eaf96f45b79485119cad65905817d
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA PDE5A ASB2 HCRTR1	1.14e-04	185	114	5	30df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WLS TPCN1 KCNJ5 SCN9A CCL8	1.14e-04	185	114	5	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC4A7 SLC4A8 STXBP4 LMO1	1.14e-04	185	114	5	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC4A7 SLC4A8 STXBP4 WLS	1.17e-04	186	114	5	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC4A7 SLC4A8 STXBP4 WLS	1.17e-04	186	114	5	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.20e-04	187	114	5	a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.20e-04	187	114	5	c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCell	droplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA ACE2 KCNJ8 PDE5A	1.20e-04	187	114	5	59313a47a6012b2413d7d3673bb05fb7e49fd88f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CACNA1D RUNX1T1 EDNRA SCN7A PDE5A	1.20e-04	187	114	5	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	TMC4 ACE2 KCNJ8 AGMO SCN7A	1.20e-04	187	114	5	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA PDE5A ASB2 HCRTR1	1.20e-04	187	114	5	8ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	TMEM176A WLS TPCN1 KCNJ5 CCL8	1.20e-04	187	114	5	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CYP4B1 PTGIR ACE2 KCNJ8	1.22e-04	99	114	4	8aab2a6989d342af387bd0823f79e7b326a12430
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CACNA1D TMEM176A RUNX1T1 EDNRA PDE5A	1.23e-04	188	114	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC4A8 ADCY9 EDNRA KCNJ8 PDE5A	1.23e-04	188	114	5	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EDNRA KLHL31 KCNJ8 ASB2	1.23e-04	188	114	5	d534ed9870405a3c1075962308f72b460aed17bf
Drug	verapamil	CACNA1B CACNA1D CACNA1S KCNG3 PTGIR PTH ADCY9 EDNRA TPCN1 ACE2 RPTOR KCNJ5 KCNJ8 SCN7A SCN9A ABCC12 NOS2	3.27e-10	490	113	17	CID000002520
Drug	isradipine	CACNA1B CACNA1D CACNA1S PTGIR TPCN1 ACE2 SIRT2 SCN7A SCN9A	1.73e-09	100	113	9	CID000003784
Drug	amiloride	CACNA1B CACNA1D CACNA1S SLC4A7 PTH EDNRA TPCN1 SLC25A3 ACE2 KCNJ8 SCN9A PDE5A	5.67e-08	315	113	12	CID000016230
Drug	nitrendipine	CACNA1B CACNA1D CACNA1S PTH EDNRA TPCN1 ACE2	5.86e-07	98	113	7	CID000004507
Drug	Verapamil	CACNA1B CACNA1D CACNA1S KCNJ11	1.00e-06	16	113	4	DB00661
Drug	arabinosyladenine	CACNA1B CACNA1D TRPV1 IMPA1 TCP11 GRIK2 PTGIR PTH ADCY9 GRK1 PRPS1L1 NF1 KCNJ5 KCNJ8 PDE5A NOS2	1.14e-06	762	113	16	CID000000191
Drug	tadalafil	IMPA1 RHBDL1 PTH EDNRA PDE5A	1.21e-06	38	113	5	CID000110635
Drug	phenytoin	CACNA1B CACNA1D CACNA1S CYP4B1 PTH TPCN1 SCN7A SCN9A NOS2	1.50e-06	219	113	9	CID000001775
Drug	felodipine	CACNA1B CACNA1D CACNA1S CYP4B1 TPCN1 ACE2 AFF1 PDE5A	2.06e-06	169	113	8	CID000003333
Drug	papaverine	CACNA1B CACNA1D CACNA1S PDE6A PTGIR ADCY9 PDE5A NOS2	2.79e-06	176	113	8	CID000004680
Drug	nitrosyliodide	IMPA1 ADAM10 EDNRA PDE5A NOS2	3.98e-06	48	113	5	CID000143560
Drug	sodium	CACNA1D CACNA1S TRPV1 SLC4A7 SLC4A8 IMPA1 SLC2A14 PTGIR PTH ADCY9 TPCN1 SLC25A3 KCNJ5 KCNJ8 SCN7A SCN9A NOS2	4.10e-06	944	113	17	CID000000923
Drug	Amlodipine	CACNA1B CACNA1D CACNA1S	4.11e-06	7	113	3	DB00381
Drug	KW-3049	CACNA1B CACNA1D CACNA1S ACE2 NOS2	4.88e-06	50	113	5	CID000002324
Drug	NSC759576	AMBN CACNA1B CACNA1D CACNA1S PTH ADCY9 TPCN1 ACE2	5.11e-06	191	113	8	CID000003075
Drug	Inactin	PTGIR EDNRA ACE2 PDE5A NOS2	6.54e-06	53	113	5	CID003032373
Drug	AC1NUZ8M	CACNA1B CACNA1D CACNA1S PTGIR TPCN1 PDE5A	6.59e-06	92	113	6	CID000073211
Drug	sildenafil	PDE6A RHBDL1 EDNRA ACE2 PDE5A NOS2	8.43e-06	96	113	6	CID000005212
Drug	Bay K 8644	CACNA1B CACNA1D CACNA1S PTH ADCY9 TPCN1 NF1	1.01e-05	150	113	7	CID000002303
Drug	nilvadipine	CACNA1B CACNA1D CACNA1S GRK1 TPCN1	1.21e-05	60	113	5	CID000004494
Drug	U46619	CACNA1B CACNA1D CACNA1S IMPA1 PTGIR ADCY9 EDNRA PDE5A NOS2	1.27e-05	285	113	9	CID000005618
Drug	pyraclofos	CACNA1B CACNA1D CACNA1S KCNG3 SCN7A SCN9A	1.49e-05	106	113	6	CID000093460
Drug	mibefradil	CACNA1B CACNA1D CACNA1S TPCN1 SCN9A	1.66e-05	64	113	5	CID000060662
Drug	gallopamil	CACNA1B CACNA1D CACNA1S PTH TPCN1	2.08e-05	67	113	5	CID000001234
Drug	caffeine	CACNA1B CACNA1D CACNA1S PDE6A IMPA1 CYP4B1 GRIK2 ADCY9 TPCN1 RPTOR PDE5A MSLN	2.34e-05	562	113	12	CID000002519
Drug	AC1L2AC7	CACNA1B CACNA1D CACNA1S TPCN1 ACE2	2.40e-05	69	113	5	CID000068733
Drug	lamotrigine	CACNA1B CACNA1D CACNA1S TPCN1 SCN7A SCN9A	2.49e-05	116	113	6	CID000003878
Drug	isoproterenol	CACNA1B CACNA1D ELP1 PTGIR PTH ADCY9 EDNRA ACE2 KCNJ8 SCN7A SCN9A PDE5A NOS2	2.81e-05	669	113	13	CID000003779
Drug	CAS 298-57-7	CACNA1B CACNA1D CACNA1S PTGIR TPCN1	3.16e-05	73	113	5	CID000002761
Drug	Calcium	CACNA1B CACNA1D TRPV1 CCR9 PTGIR PTH EDNRA NF1 RPTOR KCNJ11 SCN9A	3.50e-05	493	113	11	ctd:D002118
Drug	potassium	CACNA1B CACNA1D CACNA1S IMPA1 KCNG3 PTGIR PTH ADCY9 EDNRA TPCN1 SLC25A3 KCNJ5 KCNJ8 SCN7A SCN9A NOS2	3.80e-05	1008	113	16	CID000000813
Drug	GTP[S]	CACNA1B CACNA1D CACNA1S SSTR1 PTH ADCY9 GRK1 TPCN1 KCNJ5 KCNJ8 SCN7A SCN9A	3.81e-05	591	113	12	CID000001764
Drug	bepridil	CACNA1B CACNA1D CACNA1S TPCN1 SCN7A SCN9A	3.97e-05	126	113	6	CID000002351
Drug	AC1L1JG6	CACNA1B CACNA1D CACNA1S	4.16e-05	14	113	3	CID000005026
Drug	nifedipine	CACNA1B CACNA1D CACNA1S IMPA1 CYP4B1 PTH EDNRA TPCN1 ACE2 NOS2	4.25e-05	415	113	10	CID000004485
Drug	nisoldipine	CACNA1B CACNA1D CACNA1S PTH TPCN1	4.36e-05	78	113	5	CID000004499
Drug	baclofen	CACNA1B CACNA1D CACNA1S SPG7 ADCY9 KCNJ5 KCNJ8	4.78e-05	191	113	7	CID000002284
Drug	dihydropyridine	CACNA1B CACNA1D CACNA1S EDNRA TPCN1 ACE2 NOS2	5.11e-05	193	113	7	CID000104822
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A	CACNA1D TRPV1 SLC4A7 ADAM10 EDNRA TPCN1 NF1	5.28e-05	194	113	7	3932_DN
Drug	Barium permanganate	CACNA1B CACNA1D CACNA1S KCNJ5 KCNJ8 NOS2	5.37e-05	133	113	6	CID000024587
Drug	Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; PC3; HT_HG-U133A	PAPPA2 PDE6A TMEM176A GRIK2 RUNX1T1 PTGIR ACE2	6.00e-05	198	113	7	3711_UP
Drug	Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	TRPV1 PATZ1 GRIK2 EDNRA TPCN1 GLG1 WDFY3	6.00e-05	198	113	7	2123_DN
Drug	lanthanum	CACNA1B CACNA1D CACNA1S PTH ADCY9 TPCN1	6.09e-05	136	113	6	CID000023926
Drug	gadolinium	CACNA1B CACNA1D CACNA1S TRPV1 IMPA1 PTH NF1	6.20e-05	199	113	7	CID000023982
Drug	Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; PC3; HT_HG-U133A	TRPV1 TCP11 RUNX1T1 SEPTIN8 NF1 WDHD1 NBEAL2	6.20e-05	199	113	7	7249_UP
Drug	Thiamylal	KCNJ8 KCNJ11	7.30e-05	3	113	2	DB01154
Drug	tetracaine	CACNA1S ADCY9 TPCN1 RPTOR SCN9A	7.77e-05	88	113	5	CID000005411
Drug	cromakalim	PTGIR EDNRA KCNJ5 KCNJ8 NOS2	7.77e-05	88	113	5	CID000071191
Drug	AC1L1KC5	CACNA1B CACNA1D CACNA1S TRPV1 PTGIR PTH ADCY9 EDNRA TPCN1 SIRT2 NOS2	8.05e-05	541	113	11	CID000005428
Drug	BiM4	TRPV1 ADAM10 PTGIR PTH ADCY9 EDNRA NOS2 HCRTR1	8.55e-05	283	113	8	CID000002399
Drug	nicardipine	CACNA1B CACNA1D CACNA1S EDNRA TPCN1 ACE2	8.68e-05	145	113	6	CID000004473
Drug	manidipine	CACNA1B CACNA1D CACNA1S TPCN1 ACE2	1.12e-04	95	113	5	CID000004008
Drug	EIPA	SLC4A7 SLC4A8 PTH EDNRA SLC25A3	1.12e-04	95	113	5	CID000001795
Drug	procaine	CACNA1B CACNA1D CACNA1S TPCN1 SCN7A SCN9A	1.17e-04	153	113	6	CID000004914
Drug	glibenclamide	CACNA1D PTGIR ADCY9 EDNRA KCNJ5 KCNJ8 PDE5A ABCC12 NOS2	1.23e-04	382	113	9	CID000003488
Drug	indapamide	PTH ADCY9 ACE2 NOS2	1.40e-04	53	113	4	CID000003702
Drug	Levosimendan	KCNJ8 KCNJ11	1.46e-04	4	113	2	DB00922
Drug	5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide	EDNRA NOS2	1.46e-04	4	113	2	ctd:C085754
Drug	aldosterone	CACNA1B CACNA1D CACNA1S PTGIR PTH EDNRA ACE2 SCN9A NOS2	1.65e-04	397	113	9	CID000005839
Drug	nsc25485	IMPA1 PTH ADCY9 SLC25A3 ACE2 SCN9A PDE5A NOS2	1.67e-04	312	113	8	CID000004605
Drug	Cinildipine	CACNA1B CACNA1D CACNA1S TPCN1	1.73e-04	56	113	4	CID000002752
Drug	halothane	CACNA1B CACNA1D CACNA1S CYP4B1 PTH ADCY9 TPCN1 NOS2	1.75e-04	314	113	8	CID000003562
Drug	tetraethylammonium	CACNA1D CACNA1S KCNG3 KCNJ5 KCNJ8 SCN9A NOS2	1.79e-04	236	113	7	CID000005413
Drug	bosentan	TRPV1 PTH EDNRA PDE5A NOS2	1.87e-04	106	113	5	CID000104865
Drug	acetazolamide	CACNA1S SLC4A7 SLC4A8 PTH SLC25A3	1.96e-04	107	113	5	CID000001986
Drug	cilazaprilat	PTGIR ACE2 NOS2	1.96e-04	23	113	3	CID000064766
Drug	SR 48968	CACNA1B TRPV1 EDNRA NOS2	1.99e-04	58	113	4	CID000104974
Drug	gabapentin	CACNA1B CACNA1D CACNA1S TPCN1 SCN7A SCN9A	2.01e-04	169	113	6	CID000003446
Drug	etorphine	CACNA1B RUNX1T1 SSTR1 ADCY9	2.12e-04	59	113	4	CID000026721
Drug	Letairis	PTH EDNRA PDE5A	2.23e-04	24	113	3	CID000197712
Drug	riluzole	CACNA1B CACNA1D CACNA1S GRIK2 SCN7A SCN9A	2.35e-04	174	113	6	CID000005070
Drug	Nisoldipine	CACNA1D CACNA1S	2.42e-04	5	113	2	DB00401
Drug	AC1L8Y5L	EDNRA MSLN	2.42e-04	5	113	2	CID000410004
Drug	T-0156	PDE5A NOS2	2.42e-04	5	113	2	CID000005368
Drug	Nilvadipine	CACNA1D CACNA1S	2.42e-04	5	113	2	DB06712
Drug	bilobetin	PDE5A NOS2	2.42e-04	5	113	2	CID005315459
Drug	Nitrogen	SSTR1 GRK1	2.42e-04	5	113	2	ctd:D009584
Disease	Sinus Node Dysfunction (disorder)	CACNA1D KCNJ5 KCNJ8	2.34e-05	15	112	3	C0428908
Disease	drug-Induced dyskinesia, response to levodopa	SCGB1D4 ADAM10 CAPN13	4.17e-05	18	112	3	EFO_0010747, EFO_1000904
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1D CACNA1S	8.53e-05	4	112	2	DOID:0060173 (implicated_via_orthology)
Disease	Heart Block	CACNA1D KCNJ5	8.53e-05	4	112	2	C0018794
Disease	Auriculo-Ventricular Dissociation	CACNA1D KCNJ5	8.53e-05	4	112	2	C0004331
Disease	myocardial infarction (implicated_via_orthology)	TRPV1 EDNRA ACE2 PDE5A	1.18e-04	66	112	4	DOID:5844 (implicated_via_orthology)
Disease	pulmonary hypertension (is_implicated_in)	EDNRA ACE2 NOS2	2.01e-04	30	112	3	DOID:6432 (is_implicated_in)
Disease	Sick Sinus Syndrome	CACNA1D KCNJ5	2.12e-04	6	112	2	C0037052
Disease	Adenoma, Microcystic	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205648
Disease	Adenoma, Monomorphic	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205649
Disease	Adenoma, Basal Cell	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205646
Disease	Follicular adenoma	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205647
Disease	Papillary adenoma	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205650
Disease	Adenoma, Trabecular	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0205651
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1D CACNA1S CTNNAL1	3.47e-04	36	112	3	DOID:11723 (implicated_via_orthology)
Disease	Adenoma	CACNA1D NF1 KCNJ5	3.47e-04	36	112	3	C0001430
Disease	Chromosomal Instability	CKAP5 PPP2R5E	3.94e-04	8	112	2	C1257806
Disease	migraine (is_implicated_in)	TRPV1 EDNRA	5.05e-04	9	112	2	DOID:6364 (is_implicated_in)
Disease	sciatic neuropathy (biomarker_via_orthology)	CACNA1D NF1 KCNJ8 KCNJ11	5.61e-04	99	112	4	DOID:11446 (biomarker_via_orthology)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN7A SCN9A	6.30e-04	10	112	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN7A SCN9A	6.30e-04	10	112	2	DOID:0080422 (implicated_via_orthology)
Disease	uremia (biomarker_via_orthology)	PTH NOS2	6.30e-04	10	112	2	DOID:4676 (biomarker_via_orthology)
Disease	glucagon-like peptide-1 measurement	AMBN ULK4	6.30e-04	10	112	2	EFO_0008465
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN7A SCN9A	9.19e-04	12	112	2	DOID:0060170 (implicated_via_orthology)
Disease	Oligospermia	TPCN1 PIWIL3	9.19e-04	12	112	2	C0028960
Disease	prediabetes syndrome (biomarker_via_orthology)	SLC4A8 KCNJ11	9.19e-04	12	112	2	DOID:11716 (biomarker_via_orthology)
Disease	body mass index, fasting blood glucose measurement	ADCY9 LMO1 AGMO	9.71e-04	51	112	3	EFO_0004340, EFO_0004465
Disease	cataract (biomarker_via_orthology)	SLC2A14 ADAM10	1.08e-03	13	112	2	DOID:83 (biomarker_via_orthology)
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A8	1.45e-03	15	112	2	DOID:2355 (implicated_via_orthology)
Disease	hypertension (biomarker_via_orthology)	SLC2A14 EDNRA ACE2 KCNJ11 NOS2	1.77e-03	227	112	5	DOID:10763 (biomarker_via_orthology)
Disease	serum albumin measurement	TMEM63B TMEM176A GRIK2 KAT2A ADCY9 PRPS1L1 LMO1 ASB2	1.92e-03	592	112	8	EFO_0004535
Disease	Grand Mal Status Epilepticus	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0311335
Disease	Status Epilepticus, Subclinical	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0751522
Disease	Simple Partial Status Epilepticus	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0751524
Disease	Non-Convulsive Status Epilepticus	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0751523
Disease	Petit mal status	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0270823
Disease	Complex Partial Status Epilepticus	CCR9 SSTR1 NOS2	2.14e-03	67	112	3	C0393734
Disease	Status Epilepticus	CCR9 SSTR1 NOS2	2.23e-03	68	112	3	C0038220
Disease	diet measurement, HOMA-B	PCNX2 C3orf85	2.34e-03	19	112	2	EFO_0004469, EFO_0008111
Disease	Malignant neoplasm of breast	STXBP4 IBSP SUSD3 ELP1 GRIK2 ADAM10 EDNRA NF1 TRAPPC12 AFF1 NOS2	2.60e-03	1074	112	11	C0006142
Disease	JT interval	CACNA1D SLC4A7 LAPTM4B PTH TTC7B	2.60e-03	248	112	5	EFO_0007885
Disease	impotence (biomarker_via_orthology)	EDNRA NOS2	3.14e-03	22	112	2	DOID:1875 (biomarker_via_orthology)
Disease	Glioblastoma	GRIK2 NF1 SEPTIN14	3.41e-03	79	112	3	C0017636
Disease	epilepsy (implicated_via_orthology)	CACNA1B SCN7A SCN9A NOS2	3.51e-03	163	112	4	DOID:1826 (implicated_via_orthology)
Disease	bone density	IBSP CKAP5 OR8S1 WLS PTH ADCY9	3.70e-03	388	112	6	EFO_0003923
Disease	Intrahepatic Cholangiocarcinoma	NOS2 MSLN	3.73e-03	24	112	2	C0345905
Disease	airway responsiveness measurement	TCP11 RPTOR	3.73e-03	24	112	2	EFO_0006897
Disease	carnosine measurement	GRIK2 HCRTR1	3.73e-03	24	112	2	EFO_0010470
Disease	Extrahepatic Cholangiocarcinoma	NOS2 MSLN	3.73e-03	24	112	2	C3805278

Protein segments in the cluster

Peptide	Gene	Start	Entry
CVIFDFMDTLSDLKM	PPP2R5E	71	Q16537
TKERRVFMLNDVLMC	ARHGEF10	661	O15013
MKDLILILCLLEMSF	AMBN	11	Q9NP70
RPKAAIMETLRCLMF	AGMO	386	Q6ZNB7
IALIMLMAGFIKICS	ADAM10	686	O14672
TIMFAMKCLSLLKFL	ASB2	481	Q96Q27
RLLNLLCRSEAAMMK	AAR2	276	Q9Y312
MDKNRCELLSFLLLM	EDNRA	336	P25101
LVCFLMRLEAMAKTF	CAPN13	631	Q6MZZ7
MKVSVAALSCLMLVA	CCL15	1	Q16663
MAYKMLQVVLCSTLL	C3orf85	1	A0A1B0GTC6
LMLKCLNIVFTSMFS	CACNA1B	1501	Q00975
KLACTDMFVVELLMV	OR4N4C	186	A0A096LPK9
RQTMFELSKMFLLCL	KAT2A	251	Q92830
TLGLTLKRCYREMVM	KCNG3	311	Q8TAE7
LKRCYREMVMLLVFI	KCNG3	316	Q8TAE7
AVISMRDEKLCLMFR	KCNJ5	206	P48544
CSKLIPAFEMVMRAR	LMO1	91	P25800
KVLVKAVLFACMLMR	NOS2	516	P35228
LLKVSMSMRDCLILV	FANCI	506	Q9NVI1
FTEFLLMIFKLTMAC	FLG2	71	Q5D862
TMMKFACFERTVEAL	SLC25A3	231	Q00325
VKMCSDFLIREMSVE	KLHL31	156	Q9H511
LCFMFRVGDLRKSMI	KCNJ8	206	Q15842
LNCIMDMVEKTRRSL	RUNX1T1	361	Q06455
MRMLCLKSLRKLDLS	LRR1	171	Q96L50
SIFSMMRKEDLCRKI	NLRP11	71	P59045
RLCFEMKKGFRETML	KIAA1109	841	Q2LD37
LCFMLRVGDLRKSMI	KCNJ11	196	Q14654
MIIAGMKLLRTSFCN	PCNX2	1226	A6NKB5
KLACTDMFVVELLMV	OR4N4	186	Q8N0Y3
QKELFLAMLMTACDL	PDE5A	751	O76074
LAMLMTACDLSAITK	PDE5A	756	O76074
VMKKLCFLLQADRMS	PDE6A	81	P16499
FVCTLETLKFEAIMM	KCTD4	216	Q8WVF5
EAIMMALKCGFRLLT	KCTD4	226	Q8WVF5
ANMCIAIAISLLMIL	LAPTM4B	161	Q86VI4
AIAISLLMILICAMA	LAPTM4B	166	Q86VI4
LMFKEAFECMRKLRI	ELP1	736	O95163
MDLATFMKLRTDAVL	MSLN	526	Q13421
AMMKNCLRVNLTLAD	NOL8	476	Q76FK4
LCLLKSVTEMVISMR	OR13J1	151	Q8NGT2
MSVLRKIFVKDLDMC	PRSS54	181	Q6PEW0
FTALAILIMRLKMFL	DPY19L2	546	Q6NUT2
ACKAVLIIFRRMIME	RALGAPA2	541	Q2PPJ7
MAFCSTLMTVSLLLK	SLC2A14	366	Q8TDB8
LMTAAKFLLMRSVIE	PATZ1	136	Q9HBE1
MCKQMLRSILLLYAT	FANCD2OS	151	Q96PS1
TAKMLMVVLLVFALC	HCRTR1	296	O43613
MMCLKILRISLAILA	PAPPA2	1	Q9BXP8
VIAFCLLMILSAMAV	GASK1A	16	Q9UFP1
LKLVLFMDAMSHICR	DNAH1	2556	Q9P2D7
LDYTLMRVCKQMIKR	GLG1	876	Q92896
RLACMEEFQKAVELM	CKAP5	616	Q14008
TMLKTFTVLLFCIRM	IGSF1	11	Q8N6C5
AARAVLEKCTMMLLT	CTNNAL1	226	Q9UBT7
VDKCITKTRSMMALL	CTNNAL1	686	Q9UBT7
AFTIIFTLEMILKLM	CACNA1S	1156	Q13698
CTRVKTMTDMFLLNL	CCR9	76	P51686
LLMYMIRLCLARSAA	TMEM63B	591	Q5T3F8
MKVSAALLCLLLMAA	CCL8	1	P80075
RCNLASVMLQLLAMK	DHX33	436	Q9H6R0
FRILMCTKVTMDDFL	ACE2	356	Q9BYF1
MVFFLEDVMACTKRL	ADCY9	841	O60503
MLSMLRTMTRLCFLL	ITLN2	1	Q8WWU7
SEMKVVTAMCLLRFE	CYP4B1	461	P13584
SFCSAMVEELRMSLK	GRIK2	856	Q13002
AFETKADLCLVMTIM	GRK1	256	Q15835
TLQMGMSCLLVFKVI	PIWIL3	566	Q7Z3Z3
VLLALFTCEMLVKMY	CACNA1D	561	Q01668
IRTIQMKMCRQLLFL	C18orf63	36	Q68DL7
MVRELFEMARTKKAC	PSMC2	256	P35998
DMMLRLTSIFHLCSI	TAAR3P	111	Q9P1P4
LCYVLIIAKMRMVAL	SSTR1	241	P30872
VSCAIILLMSMAFLT	SUSD3	111	Q96L08
ILLMSMAFLTCCLLK	SUSD3	116	Q96L08
MVLALVFVRKLMDLC	SLC4A7	1111	Q9Y6M7
FVKLRDMLLCTNMEN	SEPTIN14	281	Q6ZU15
VRRLHLCTSFMDMLK	TMEM176A	171	Q96HP8
LCTSFMDMLKALFRT	TMEM176A	176	Q96HP8
CQFKLLRMAVALICM	RHBDL3	301	P58872
TVRMVLSNMEKLFCI	IMPA1	171	P29218
CIKRSLLEMMLESAL	NBEAL2	1491	Q6ZNJ1
AVDIACRTLMFLKLM	GNRHR2	21	Q96P88
DMNRMELLKLLLTCF	HID1	201	Q8IV36
KILVHSLFSMLIMCT	SCN9A	121	Q15858
ILLSILGMACAFSMK	IBSP	6	P21815
CMQSDFLKVDLLLVM	SIRT2	246	Q8IXJ6
YALELLARKCMMISV	WDR17	1006	Q8IZU2
MVLALVFVRKVMDLC	SLC4A8	981	Q2Y0W8
LFTKEQLFERMCMAL	SPG7	616	Q9UQ90
ENLMLLLMIRADSCL	OR8S1	41	Q8NH09
SLMELLIMINACKIA	PRPS1L1	66	P21108
IMVLDCQLRKSEMAR	STXBP4	406	Q6ZWJ1
TMNEFLTCIRLIKMY	ABCC12	301	Q96J65
PYKLLRMVLALVCMS	RHBDL1	336	O75783
MKDRMKTVSVALVLC	RPTOR	51	Q8N122
SILNMAMFRCKKDIA	AFF1	1056	P51825
RMALVSALLLMLFCV	RNF223	196	E7ERA6
KMFEATRLLATIVML	SFT2D1	91	Q8WV19
KYVLNMMALLCAPVR	TCP11	161	Q8WWU5
MRLSVCLLMVSLALC	SCGB1D4	1	Q6XE38
CTEAVFLLLGMLRSM	WDFY3	1836	Q8IZQ1
EFSRGLMMLVLEKLA	RINT1	371	Q6NUQ1
MANCLLLMKDYVLAV	TRAPPC12	551	Q8WVT3
AVMIEKMILRDLCRF	TRPV1	566	Q8NER1
SMLILFAMAVERCLA	PTGIR	106	P43119
KLNMACLKALMDVVR	TMEM232	316	C9JQI7
MKMLALSCKLEREFR	WDHD1	766	O75717
CVMTIGEMLRSFLTK	PRPF38B	196	Q5VTL8
LLLNVLASVLMACMT	TMC4	171	Q7Z404
VSKFMDRLLSLMVCN	NF1	891	P21359
MASCLALRMALLLVS	SNORC	1	Q6UX34
CDFVKLREMLIRVNM	SEPTIN8	271	Q92599
DLAIIFLSCVMKSKM	TMEM44	306	Q2T9K0
VKLREMLICTNMEDL	SEPTIN10	296	Q9P0V9
FALMVVVFELCMKLR	TPCN1	146	Q9ULQ1
ALYMIRMKDSLICLD	USP41	166	Q3LFD5
QREMKMFLEKLCFEL	TRIM10	291	Q9UDY6
MLSECLERAMKFAFE	TTC7B	381	Q86TV6
VMLYTMECILKLIAF	SCN7A	1291	Q01118
RFKFLMLITLACAAM	WLS	431	Q5T9L3
MIVMLAICFLTKSDG	PTH	11	P01270
MLLLSCQARLVMYIE	ULK4	766	Q96C45
FVMDMIAFEKACERL	LRRIQ3	586	A6PVS8