Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cell morphogenesis	ADGRB3 LRP1 LRP2 PLXNA3 TSC2 KIF5A P2RX7 FGD6 ITGB3 ZMYM6 NOTCH2 SIPA1L3	6.48e-06	1194	45	12	GO:0000902
GeneOntologyBiologicalProcess	regulation of cell adhesion	LRP1 SELP FGB PLXNA3 TSC2 ZBTB16 ITGB3 IL4R SPRY4 NPNT	2.43e-05	927	45	10	GO:0030155
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP1 LRP2	4.63e-05	5	45	2	GO:1905167
GeneOntologyBiologicalProcess	chemoattraction of axon	LRP1 LRP2	4.63e-05	5	45	2	GO:0061642
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LRP1 LRP2	9.71e-05	7	45	2	GO:1904352
GeneOntologyBiologicalProcess	regulation of cell size	LRP1 PLXNA3 SLC12A8 TSC2 P2RX7	1.27e-04	225	45	5	GO:0008361
GeneOntologyBiologicalProcess	positive regulation of ERK1 and ERK2 cascade	LRP1 FGB ITGB3 NOTCH2 NPNT	1.71e-04	240	45	5	GO:0070374
GeneOntologyBiologicalProcess	regulation of cell-substrate adhesion	LRP1 FGB ITGB3 SPRY4 NPNT	2.22e-04	254	45	5	GO:0010810
GeneOntologyBiologicalProcess	positive regulation of cell adhesion	SELP FGB TSC2 ZBTB16 ITGB3 IL4R NPNT	2.38e-04	579	45	7	GO:0045785
GeneOntologyBiologicalProcess	tissue remodeling	LRP1 P2RX7 DLL4 ITGB3 NOTCH2	2.57e-04	262	45	5	GO:0048771
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	LRP1 LRP2 ITGB3 NOTCH2 SPRY4 NPNT	2.58e-04	412	45	6	GO:0090287
GeneOntologyBiologicalProcess	regulation of lysosomal protein catabolic process	LRP1 LRP2	3.03e-04	12	45	2	GO:1905165
GeneOntologyBiologicalProcess	positive regulation of cell development	LRP1 LRP2 PLXNA3 ZBTB16 ITGB3 IL4R NOTCH2	3.40e-04	614	45	7	GO:0010720
GeneOntologyBiologicalProcess	cell projection morphogenesis	ADGRB3 LRP1 LRP2 PLXNA3 TSC2 KIF5A ITGB3 NOTCH2	3.70e-04	826	45	8	GO:0048858
GeneOntologyBiologicalProcess	axon guidance	LRP1 LRP2 PLXNA3 KIF5A NOTCH2	3.78e-04	285	45	5	GO:0007411
GeneOntologyBiologicalProcess	regulation of nervous system development	ADGRB3 LRP1 LRP2 PLXNA3 TSC2 DLL4 NOTCH2	3.78e-04	625	45	7	GO:0051960
GeneOntologyBiologicalProcess	neuron projection guidance	LRP1 LRP2 PLXNA3 KIF5A NOTCH2	3.84e-04	286	45	5	GO:0097485
GeneOntologyBiologicalProcess	regulation of substrate adhesion-dependent cell spreading	FGB ITGB3 SPRY4	4.03e-04	66	45	3	GO:1900024
GeneOntologyBiologicalProcess	regulation of protein catabolic process in the vacuole	LRP1 LRP2	4.17e-04	14	45	2	GO:1904350
GeneOntologyBiologicalProcess	regulation of cell development	LRP1 LRP2 PLXNA3 TSC2 ZBTB16 DLL4 ITGB3 IL4R NOTCH2	5.09e-04	1095	45	9	GO:0060284
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	LRP1 LRP2 FGB TSC2 P2RX7 ITGB3 IL4R	5.58e-04	667	45	7	GO:0060627
GeneOntologyBiologicalProcess	cell activation	LRP1 SELP FGB TSC2 ZBTB16 P2RX7 DLL4 ITGB3 IL4R NOTCH2	5.59e-04	1356	45	10	GO:0001775
GeneOntologyBiologicalProcess	morphogenesis of an epithelial sheet	DLL4 ITGB3 NOTCH2	5.64e-04	74	45	3	GO:0002011
GeneOntologyBiologicalProcess	positive chemotaxis	LRP1 LRP2 TSC2	5.87e-04	75	45	3	GO:0050918
GeneOntologyBiologicalProcess	blood coagulation, fibrin clot formation	FGB ITGB3	6.20e-04	17	45	2	GO:0072378
GeneOntologyBiologicalProcess	COPII-coated vesicle cargo loading	SEC24D SEC24C	6.96e-04	18	45	2	GO:0090110
GeneOntologyBiologicalProcess	positive regulation of neural precursor cell proliferation	LRP2 DLL4 NOTCH2	7.09e-04	80	45	3	GO:2000179
GeneOntologyBiologicalProcess	aorta development	LRP1 LRP2 DLL4	7.09e-04	80	45	3	GO:0035904
GeneOntologyCellularComponent	external side of plasma membrane	LRP1 SELP LRP2 FGB P2RX7 ITGB3 IL4R	1.12e-04	519	45	7	GO:0009897
GeneOntologyCellularComponent	side of membrane	LRP1 SELP LRP2 FGB XPNPEP2 P2RX7 ITGB3 IL4R	4.96e-04	875	45	8	GO:0098552
GeneOntologyCellularComponent	COPII vesicle coat	SEC24D SEC24C	5.33e-04	16	45	2	GO:0030127
GeneOntologyCellularComponent	platelet alpha granule membrane	SELP ITGB3	6.04e-04	17	45	2	GO:0031092
GeneOntologyCellularComponent	platelet alpha granule	SELP FGB ITGB3	1.06e-03	93	45	3	GO:0031091
GeneOntologyCellularComponent	intermediate filament	KRTAP13-1 KRTAP13-2 KRT34 KRTAP1-3	1.42e-03	227	45	4	GO:0005882
GeneOntologyCellularComponent	receptor complex	LRP1 LRP2 PLXNA3 ITGB3 IL4R NOTCH2	1.46e-03	581	45	6	GO:0043235
GeneOntologyCellularComponent	growth cone	LRP1 LRP2 TSC2 KIF5A	1.88e-03	245	45	4	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	LRP1 LRP2 TSC2 KIF5A	2.11e-03	253	45	4	GO:0030427
GeneOntologyCellularComponent	cell surface	LRP1 SELP LRP2 FGB P2RX7 ITGB3 IL4R NOTCH2	2.31e-03	1111	45	8	GO:0009986
GeneOntologyCellularComponent	distal axon	LRP1 LRP2 TSC2 KIF5A P2RX7	2.35e-03	435	45	5	GO:0150034
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP13-1 KRTAP13-2 KRT34 KRTAP1-3	2.43e-03	263	45	4	GO:0045111
Domain	EGF_1	LRP1 SELP LRP2 DLL4 ITGB3 ATRNL1 NOTCH2 NPNT	1.25e-07	255	44	8	PS00022
Domain	EGF-like_CS	LRP1 SELP LRP2 DLL4 ITGB3 ATRNL1 NOTCH2 NPNT	1.50e-07	261	44	8	IPR013032
Domain	EGF_2	LRP1 SELP LRP2 DLL4 ITGB3 ATRNL1 NOTCH2 NPNT	1.68e-07	265	44	8	PS01186
Domain	EGF	LRP1 SELP LRP2 DLL4 ITGB3 NOTCH2	4.79e-07	126	44	6	PF00008
Domain	EGF_3	LRP1 SELP LRP2 DLL4 ATRNL1 NOTCH2 NPNT	1.18e-06	235	44	7	PS50026
Domain	EGF	LRP1 SELP LRP2 DLL4 ATRNL1 NOTCH2 NPNT	1.18e-06	235	44	7	SM00181
Domain	EGF-like_dom	LRP1 SELP LRP2 DLL4 ATRNL1 NOTCH2 NPNT	1.73e-06	249	44	7	IPR000742
Domain	ASX_HYDROXYL	LRP1 LRP2 DLL4 NOTCH2 NPNT	3.66e-06	100	44	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP1 LRP2 DLL4 NOTCH2 NPNT	4.88e-06	106	44	5	IPR000152
Domain	EGF_CA	LRP1 LRP2 DLL4 NOTCH2 NPNT	9.70e-06	122	44	5	SM00179
Domain	EGF-like_Ca-bd_dom	LRP1 LRP2 DLL4 NOTCH2 NPNT	1.05e-05	124	44	5	IPR001881
Domain	EGF_extracell	LRP2 DLL4 ITGB3 ATRNL1	1.19e-05	60	44	4	IPR013111
Domain	EGF_2	LRP2 DLL4 ITGB3 ATRNL1	1.19e-05	60	44	4	PF07974
Domain	Growth_fac_rcpt_	LRP1 LRP2 DLL4 NOTCH2 NPNT	3.18e-05	156	44	5	IPR009030
Domain	EGF_CA	LRP1 LRP2 NOTCH2 NPNT	4.94e-05	86	44	4	PF07645
Domain	EGF_Ca-bd_CS	LRP1 LRP2 NOTCH2 NPNT	7.91e-05	97	44	4	IPR018097
Domain	Sec23/24_helical_dom	SEC24D SEC24C	8.09e-05	6	44	2	IPR006900
Domain	Sec23_24_beta_S	SEC24D SEC24C	8.09e-05	6	44	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24D SEC24C	8.09e-05	6	44	2	PF04810
Domain	Sec23_trunk	SEC24D SEC24C	8.09e-05	6	44	2	PF04811
Domain	Sec23_helical	SEC24D SEC24C	8.09e-05	6	44	2	PF04815
Domain	Sec23_BS	SEC24D SEC24C	8.09e-05	6	44	2	PF08033
Domain	Sec23/24_trunk_dom	SEC24D SEC24C	8.09e-05	6	44	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24D SEC24C	8.09e-05	6	44	2	IPR006895
Domain	EGF_CA	LRP1 LRP2 NOTCH2 NPNT	8.57e-05	99	44	4	PS01187
Domain	PSI	PLXNA3 ITGB3 ATRNL1	1.51e-04	44	44	3	IPR016201
Domain	PSI	PLXNA3 ITGB3 ATRNL1	1.73e-04	46	44	3	SM00423
Domain	Rap_GAP	TSC2 SIPA1L3	2.41e-04	10	44	2	PF02145
Domain	Rap_GAP_dom	TSC2 SIPA1L3	2.94e-04	11	44	2	IPR000331
Domain	RAPGAP	TSC2 SIPA1L3	2.94e-04	11	44	2	PS50085
Domain	PMG	KRTAP13-1 KRTAP13-2	4.16e-04	13	44	2	PF05287
Domain	KRTAP_PMG	KRTAP13-1 KRTAP13-2	4.16e-04	13	44	2	IPR007951
Domain	Gelsolin	SEC24D SEC24C	4.85e-04	14	44	2	PF00626
Domain	Gelsolin-like_dom	SEC24D SEC24C	4.85e-04	14	44	2	IPR007123
Domain	TIL_dom	LRP2 MUC5AC	4.85e-04	14	44	2	IPR002919
Domain	Ldl_recept_b	LRP1 LRP2	4.85e-04	14	44	2	PF00058
Domain	LDLRB	LRP1 LRP2	4.85e-04	14	44	2	PS51120
Domain	LY	LRP1 LRP2	5.59e-04	15	44	2	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP2	5.59e-04	15	44	2	IPR000033
Domain	-	SEC24D SEC24C ITGB3	7.04e-04	74	44	3	3.40.50.410
Domain	ADF-H/Gelsolin-like_dom	SEC24D SEC24C	1.45e-03	24	44	2	IPR029006
Domain	-	SEC24D SEC24C	1.45e-03	24	44	2	3.40.20.10
Domain	VWF_A	SEC24D SEC24C ITGB3	1.63e-03	99	44	3	IPR002035
Domain	cEGF	LRP1 LRP2	1.70e-03	26	44	2	IPR026823
Domain	cEGF	LRP1 LRP2	1.70e-03	26	44	2	PF12662
Domain	PSI	PLXNA3 ATRNL1	2.57e-03	32	44	2	PF01437
Domain	Plexin_repeat	PLXNA3 ATRNL1	2.57e-03	32	44	2	IPR002165
Domain	-	LRP1 LRP2	3.80e-03	39	44	2	2.120.10.30
Domain	LDLR_class-A_CS	LRP1 LRP2	4.00e-03	40	44	2	IPR023415
Domain	Ldl_recept_a	LRP1 LRP2	5.04e-03	45	44	2	PF00057
Domain	-	LRP1 LRP2	5.26e-03	46	44	2	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	LRP1 LRP2	5.26e-03	46	44	2	IPR011042
Domain	LDLRA_1	LRP1 LRP2	5.71e-03	48	44	2	PS01209
Domain	LDLRA_2	LRP1 LRP2	5.95e-03	49	44	2	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LRP2	5.95e-03	49	44	2	IPR002172
Domain	LDLa	LRP1 LRP2	5.95e-03	49	44	2	SM00192
Domain	CUB	ADGRB3 ATRNL1	6.93e-03	53	44	2	PS01180
Pathway	WP_COMPLEMENT_SYSTEM	SELP LRP2 FGB ITGB3	7.10e-05	96	33	4	M39581
Pathway	PID_UPA_UPAR_PATHWAY	LRP1 FGB ITGB3	1.26e-04	42	33	3	M174
Pathway	KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION	SEC24D SEC24C	3.46e-04	12	33	2	M47770
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL4 NOTCH2	4.08e-04	13	33	2	M47423
Pathway	REACTOME_KERATINIZATION	KRTAP13-1 KRTAP13-2 KRT34 KRTAP1-3	4.27e-04	153	33	4	MM15343
Pathway	PID_IL4_2PATHWAY	SELP ITGB3 IL4R	4.42e-04	64	33	3	M28
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	FGB ITGB3	5.47e-04	15	33	2	M12101
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	FGB ITGB3	5.47e-04	15	33	2	M1262
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	FGB ITGB3	5.47e-04	15	33	2	MM14959
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	FGB ITGB3	5.47e-04	15	33	2	MM14961
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING	TSC2 IRS4 ITGB3 IL4R LPAR6	6.33e-04	302	33	5	M39719
Pathway	WP_HYPOXIADEPENDENT_PROLIFERATION_OF_MYOBLASTS	TRIM63 TSC2	8.86e-04	19	33	2	MM15811
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY	TSC2 IRS4 ITGB3 IL4R LPAR6	8.94e-04	326	33	5	MM15917
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	PLXNA3 KRTAP13-1 KRTAP13-2 ITGB3 KRT34 KRTAP1-3	9.66e-04	502	33	6	MM14537
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL4 NOTCH2	1.19e-03	22	33	2	M27210
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	LRP1 SELP LRP2 ITGB3 IL4R NOTCH2	3.83e-09	101	45	6	23382219
Pubmed	LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.	LRP1 DLL4 NOTCH2	8.09e-09	4	45	3	38462037
Pubmed	The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.	SELP FGB ITGB3	2.41e-07	10	45	3	12082590
Pubmed	A candidate gene association study of 77 polymorphisms in migraine.	SELP FGB ITGB3 IL4R	6.32e-07	52	45	4	19559392
Pubmed	A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.	SELP FGB ITGB3 IL4R	1.47e-06	64	45	4	19131662
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	1.64e-06	2	45	2	34445520
Pubmed	The association of beta-fibrinogen 455 G/A gene polymorphism with left atrial thrombus and severe spontaneous echo contrast in atrial fibrillation.	FGB ITGB3	1.64e-06	2	45	2	20538554
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP1 LRP2 MUC5AC ATRNL1	2.23e-06	71	45	4	33541421
Pubmed	Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.	SELP FGB ITGB3	3.06e-06	22	45	3	12871600
Pubmed	Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro.	DLL4 NOTCH2	4.91e-06	3	45	2	27073072
Pubmed	Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src.	ITGB3 SPRY4	4.91e-06	3	45	2	23955631
Pubmed	Notch signaling regulates follicular helper T cell differentiation.	IL4R NOTCH2	4.91e-06	3	45	2	23918982
Pubmed	P-selectin expression, but not GPIIb/IIIa activation, is enhanced in the inflammatory stage of Takayasu's arteritis.	SELP ITGB3	4.91e-06	3	45	2	16636497
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5AC IL4R	4.91e-06	3	45	2	29802623
Pubmed	O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells.	DLL4 NOTCH2	4.91e-06	3	45	2	33351914
Pubmed	KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy.	DLL4 NOTCH2	4.91e-06	3	45	2	38973459
Pubmed	Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice.	SELP ITGB3	4.91e-06	3	45	2	17996853
Pubmed	A triple arg motif mediates α(2B)-adrenergic receptor interaction with Sec24C/D and export.	SEC24D SEC24C	4.91e-06	3	45	2	22404651
Pubmed	Relationship of Platelet Glycoprotein IIb/IIIa and CD62P With Hypercoagulable State After Oncologic Surgery.	SELP ITGB3	4.91e-06	3	45	2	33259230
Pubmed	Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.	DLL4 NOTCH2	4.91e-06	3	45	2	28572448
Pubmed	Muc5ac: a critical component mediating the rejection of enteric nematodes.	MUC5AC IL4R	4.91e-06	3	45	2	21502330
Pubmed	Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994.	FGB ITGB3 IL4R	5.15e-06	26	45	3	21054877
Pubmed	Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.	DLL4 MUC5AC NOTCH2	5.79e-06	27	45	3	21791528
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	9.81e-06	4	45	2	12413896
Pubmed	Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.	DLL4 NOTCH2	9.81e-06	4	45	2	32820046
Pubmed	Polymorphisms of Platelet Glycoprotein Receptors and Cell Adhesion Molecules in Fetuses with Fetal Growth Restriction and Their Mothers As Detected with Pyrosequencing.	SELP ITGB3	9.81e-06	4	45	2	28358707
Pubmed	Analysis of plasminogen activator inhibitor-1, integrin beta3, beta fibrinogen, and methylenetetrahydrofolate reductase polymorphisms in Iranian women with recurrent pregnancy loss.	FGB ITGB3	9.81e-06	4	45	2	21241403
Pubmed	Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.	LRP1 SELP	9.81e-06	4	45	2	15769472
Pubmed	Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins.	SELP ITGB3	9.81e-06	4	45	2	11071623
Pubmed	Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.	DLL4 NOTCH2	9.81e-06	4	45	2	28319044
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2	9.81e-06	4	45	2	7775583
Pubmed	Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.	LRP1 LRP2	9.81e-06	4	45	2	11421580
Pubmed	Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.	ZBTB16 IL4R	9.81e-06	4	45	2	25848867
Pubmed	Murine SEC24D can substitute functionally for SEC24C during embryonic development.	SEC24D SEC24C	9.81e-06	4	45	2	34702932
Pubmed	Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.	DLL4 LPAR6	9.81e-06	4	45	2	31335323
Pubmed	Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.	CGB2 DLL4 NOTCH2	1.18e-05	34	45	3	17015435
Pubmed	Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.	DLL4 NOTCH2	1.63e-05	5	45	2	21726900
Pubmed	ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.	LRP1 LRP2	1.63e-05	5	45	2	16101684
Pubmed	Mammalian COPII coat component SEC24C is required for embryonic development in mice.	SEC24D SEC24C	1.63e-05	5	45	2	24876386
Pubmed	[Associations of hemostasis factors genes with early development of ischemic heart disease and manifestation of myocardial infarction in young age].	FGB ITGB3	1.63e-05	5	45	2	16353042
Pubmed	Platelet polymorphisms: frequency distribution and association with coronary artery disease in an Indian population.	FGB ITGB3	1.63e-05	5	45	2	21034162
Pubmed	Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).	DLL4 NOTCH2	1.63e-05	5	45	2	23675950
Pubmed	Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins.	SELP ITGB3	1.63e-05	5	45	2	14718670
Pubmed	T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.	ZBTB16 IL4R	1.63e-05	5	45	2	20601952
Pubmed	Inflammation induces hemorrhage in thrombocytopenia.	SELP ITGB3	1.63e-05	5	45	2	18256319
Pubmed	MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury.	P2RX7 ITGB3	1.63e-05	5	45	2	23454767
Pubmed	Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.	FGB ITGB3	1.63e-05	5	45	2	14963283
Pubmed	Analysis of inherited thrombophilic mutations and natural anticoagulant deficiency in patients with idiopathic portal hypertension.	FGB ITGB3	1.63e-05	5	45	2	18685811
Pubmed	Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo.	FGB ITGB3	1.63e-05	5	45	2	16824188
Pubmed	Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.	DLL4 NOTCH2	1.63e-05	5	45	2	30181175
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP1 LRP2	1.63e-05	5	45	2	19047013
Pubmed	Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice.	DLL4 NOTCH2	1.63e-05	5	45	2	35064244
Pubmed	Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways.	FGB ITGB3	1.63e-05	5	45	2	10605720
Pubmed	Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.	LRP1 LRP2	1.63e-05	5	45	2	18685438
Pubmed	Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.	SELP FGB ITGB3	1.65e-05	38	45	3	16263699
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	DLL4 MUC5AC NOTCH2	2.08e-05	41	45	3	22675208
Pubmed	Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression.	SELP ITGB3	2.45e-05	6	45	2	19332769
Pubmed	Connection between genetically determined blood coagulation factors and haemorheology.	FGB ITGB3	2.45e-05	6	45	2	18503143
Pubmed	Sec24 proteins and sorting at the endoplasmic reticulum.	SEC24D SEC24C	2.45e-05	6	45	2	10075675
Pubmed	Spectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population.	FGB ITGB3	2.45e-05	6	45	2	12518110
Pubmed	Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.	LRP1 LRP2	2.45e-05	6	45	2	9837937
Pubmed	Mutations and polymorphisms in genes affecting haemostasis components in children with thromboembolic events.	FGB ITGB3	2.45e-05	6	45	2	17230042
Pubmed	A family of mammalian proteins homologous to yeast Sec24p.	SEC24D SEC24C	2.45e-05	6	45	2	10329445
Pubmed	Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis.	FGB ITGB3	2.45e-05	6	45	2	18803625
Pubmed	Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.	DLL4 NOTCH2	2.45e-05	6	45	2	19217325
Pubmed	Role of thrombophilic gene polymorphisms in branch retinal vein occlusion.	FGB ITGB3	2.45e-05	6	45	2	16157382
Pubmed	Gender differences in genetic risk profiles for cardiovascular disease.	SELP FGB ITGB3	2.96e-05	46	45	3	18974842
Pubmed	Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.	LRP1 LRP2 MUC5AC	3.15e-05	47	45	3	11208732
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ADGRB3 LRP1 LRP2 TSC2 TM2D3 KIF5A ATRNL1 SIPA1L3 DOP1B	3.33e-05	1285	45	9	35914814
Pubmed	Selective export of human GPI-anchored proteins from the endoplasmic reticulum.	SEC24D SEC24C	3.42e-05	7	45	2	20427317
Pubmed	Prothrombotic polymorphisms, mutations, and their association with pediatric non-cardioembolic stroke in Asian-Indian patients.	FGB ITGB3	3.42e-05	7	45	2	18836720
Pubmed	Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke.	FGB ITGB3	3.42e-05	7	45	2	16567932
Pubmed	Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study.	SELP IL4R	3.42e-05	7	45	2	16184405
Pubmed	GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.	DLL4 NOTCH2	3.42e-05	7	45	2	32060138
Pubmed	Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population.	FGB ITGB3	3.42e-05	7	45	2	15968394
Pubmed	Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage.	FGB ITGB3	3.42e-05	7	45	2	16635210
Pubmed	Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.	DLL4 NOTCH2	3.42e-05	7	45	2	27576369
Pubmed	Early pregnancy loss in celiac women: The role of genetic markers of thrombophilia.	FGB ITGB3	3.42e-05	7	45	2	19395327
Pubmed	The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.	LRP1 LRP2	3.42e-05	7	45	2	12169628
Pubmed	The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.	DLL4 NOTCH2	3.42e-05	7	45	2	30289388
Pubmed	Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice.	SELP FGB	3.42e-05	7	45	2	10749569
Pubmed	Thrombophilic gene polymorphisms are risk factors for unexplained infertility.	FGB ITGB3	3.42e-05	7	45	2	18930220
Pubmed	The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand.	SELP ITGB3	3.42e-05	7	45	2	37184585
Pubmed	Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.	FGB ITGB3 IL4R	3.58e-05	49	45	3	18936436
Pubmed	Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.	FGB ITGB3	4.56e-05	8	45	2	27221710
Pubmed	Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.	SELP FGB IL4R	4.79e-05	54	45	3	20536507
Pubmed	Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.	SELP ITGB3 IL4R	5.64e-05	57	45	3	19263529
Pubmed	Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling.	SELP FGB IL4R	5.64e-05	57	45	3	19479237
Pubmed	Impact of genetic polymorphisms on platelet function and aspirin resistance.	FGB ITGB3	5.86e-05	9	45	2	19923980
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	DLL4 NOTCH2	5.86e-05	9	45	2	16245338
Pubmed	LDL receptor-related protein as a component of the midkine receptor.	LRP1 LRP2	5.86e-05	9	45	2	10772929
Pubmed	TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects.	FGB IL4R	5.86e-05	9	45	2	17115186
Pubmed	Platelet alpha-granules.	SELP ITGB3	5.86e-05	9	45	2	8467233
Pubmed	Candidate genetic markers and the risk of restenosis after coronary angioplasty.	FGB ITGB3	5.86e-05	9	45	2	12899665
Pubmed	The endothelial Dll4-muscular Notch2 axis regulates skeletal muscle mass.	DLL4 NOTCH2	5.86e-05	9	45	2	35228746
Pubmed	Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.	FGB ITGB3 IL4R	6.58e-05	60	45	3	12082592
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	DLL4 NOTCH2	7.32e-05	10	45	2	23665443
Pubmed	The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.	SEC24D SEC24C	7.32e-05	10	45	2	17499046
Pubmed	A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.	FGB ITGB3	7.32e-05	10	45	2	19906129
Pubmed	Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients.	FGB ITGB3	7.32e-05	10	45	2	20425806
Interaction	KLHL38 interactions	KRTAP13-1 KRTAP13-2 KRT34 SPRY4 KRTAP1-3	2.41e-06	99	44	5	int:KLHL38
Interaction	STK16 interactions	KRTAP13-1 KRTAP13-2 SPRY4 KRTAP1-3 DOP1B	2.15e-05	155	44	5	int:STK16
Cytoband	21q22.1	KRTAP13-1 KRTAP13-2	6.80e-04	39	45	2	21q22.1
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2	2.80e-04	13	35	2	634
GeneFamily	Keratin associated proteins	KRTAP13-1 KRTAP13-2 KRTAP1-3	1.21e-03	109	35	3	619
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP ATRNL1	2.85e-03	41	35	2	1298
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	LRP1 SELP ITGB3 IL4R	6.82e-03	394	35	4	471
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 SELP P2RX7 LPAR6 FAM219A	7.62e-07	169	45	5	7c994653b0d629dfb046755d6b678452de0a15d2
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRTAP13-1 KRT34 NOTCH2 KRTAP1-3	9.90e-06	133	45	4	f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LRP2 DLL4 SENP7 NPNT	2.37e-05	166	45	4	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	Control\|World / group, cell type (main and fine annotations)	LRP2 ZBTB16 MUC5AC NPNT	2.48e-05	168	45	4	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MED12L PAQR5 SEC24D KIF5A	2.97e-05	176	45	4	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MED12L PAQR5 SEC24D KIF5A	2.97e-05	176	45	4	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2 NOTCH2	3.11e-05	178	45	4	cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP SLC12A8 SLC13A2 SPRY4	3.32e-05	181	45	4	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2 NOTCH2	3.54e-05	184	45	4	235890e8b424f4386b6ea52d173d20a00898df73
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP KIF5A DLL4 ITGB3	3.61e-05	185	45	4	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	10x3'2.3-week_17-19-Hematopoietic-MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.01e-05	190	45	4	64060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.09e-05	191	45	4	7edc22e7e70697fb22690699efb352577162709b
ToppCell	10x3'2.3-week_17-19-Hematopoietic-MK-early_MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.09e-05	191	45	4	3839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	LRP2 PAQR5 ZBTB16 NPNT	4.18e-05	192	45	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 FGB XPNPEP2 SLC13A2	4.18e-05	192	45	4	3e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.26e-05	193	45	4	3d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCell	IPF-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	ADGRB3 SELP ZBTB16 IL4R	4.35e-05	194	45	4	e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.35e-05	194	45	4	245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCell	10x3'2.3-week_14-16-Hematopoietic-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.35e-05	194	45	4	216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-early_MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.44e-05	195	45	4	fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.44e-05	195	45	4	1e794839a251fbc6e6ce419b4c457ead35a04735
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK-early_MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.44e-05	195	45	4	9b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK-early_MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MED12L SELP ZBTB16 ITGB3	4.53e-05	196	45	4	fc541e328aed28e84d5b3835169c60da0d64cddc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 SELP DLL4 IL4R	4.53e-05	196	45	4	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 SELP DLL4 IL4R	4.53e-05	196	45	4	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 SELP DLL4 IL4R	4.53e-05	196	45	4	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP ZBTB16 DLL4 IL4R	4.71e-05	198	45	4	b11d21aa96a0c91e958ae7ed8fd56546aeaebb91
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP ZBTB16 DLL4 IL4R	4.71e-05	198	45	4	605ef5b61750226b93bca48166d8a1f6450e80e0
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SELP ZBTB16 IL4R LPAR6	4.89e-05	200	45	4	2ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCell	distal-Endothelial-Capillary-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZBTB16 DLL4 IL4R LPAR6	4.89e-05	200	45	4	ab96d3d801373459a2503ccfb665dc3f43bfb5a1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	1.54e-04	103	45	3	39d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	1.54e-04	103	45	3	01a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LRP2 KRT34 NPNT	2.19e-04	116	45	3	3a11fde2b0a0dad26f6876a3ab3949edfb8b97e2
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LRP2 KRT34 NPNT	2.19e-04	116	45	3	c1a8d8068efb0e6b88f230df351094b69a4e56e2
ToppCell	PBMC-Control-Hematopoietic-RBC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LRP2 KRT34 NPNT	2.19e-04	116	45	3	ca72dfb23c3335cb6bb0d1be5dc032e044eaff1a
ToppCell	Control-Hematopoietic_R-RBC\|Control / Disease group, lineage and cell class	LRP2 KRT34 NPNT	2.25e-04	117	45	3	2f8fa933b76f40d2f07391b0f7394483e25bd642
ToppCell	Control-Hematopoietic_R\|Control / Disease group, lineage and cell class	LRP2 KRT34 NPNT	2.25e-04	117	45	3	48c909e3e068d1da5d39f1cf23a321d5e1f31a74
ToppCell	PBMC-Control-Hematopoietic-RBC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRP2 KRT34 NPNT	2.30e-04	118	45	3	e1fb21a8ec0f7b8b828d12e5dc8b470dbf3dc810
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRP2 KRT34 NPNT	2.30e-04	118	45	3	25d35c13d51a347e305f3a3ce239800cf118848e
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRP2 KRT34 NPNT	2.30e-04	118	45	3	68a891a0597d206ad5f66c6e087126f020e972b5
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	3.42e-04	135	45	3	4cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	3.42e-04	135	45	3	6bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	3.42e-04	135	45	3	7e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOXD2 TRIM63 XPNPEP2	3.42e-04	135	45	3	97989546826bf3739e1b86a10832a457fd37c5d2
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LRP1 NOTCH2 NPNT	3.57e-04	137	45	3	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	FGB ZBTB16 SLC13A2	4.05e-04	143	45	3	bcf702f976ab91f82a5a4beb0b7c74a372c42ae6
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SELP IRS4 ZBTB16	4.21e-04	145	45	3	78f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MED12L SLC12A8 TSC2	4.56e-04	149	45	3	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MED12L SLC12A8 TSC2	4.56e-04	149	45	3	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MED12L ATRNL1 SPRY4	5.31e-04	157	45	3	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB16 ITGB3 LPAR6	5.51e-04	159	45	3	5c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MED12L P2RX7 IL4R	5.82e-04	162	45	3	228e33678c7f963b3032a218333f206e5fff1292
ToppCell	Club-club-12\|World / Class top	SLC13A2 MUC5AC KRT34	6.14e-04	165	45	3	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MED12L SELP ITGB3	6.14e-04	165	45	3	d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MED12L P2RX7 IL4R	6.14e-04	165	45	3	cece16b03282d27fb49102eb9c104a2024efd28c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 KIF5A P2RX7	6.25e-04	166	45	3	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 KIF5A P2RX7	6.25e-04	166	45	3	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 KIF5A P2RX7	6.25e-04	166	45	3	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 KIF5A P2RX7	6.25e-04	166	45	3	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MED12L FGD6 IL4R	6.47e-04	168	45	3	08eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 ITGB3 DOP1B	6.47e-04	168	45	3	f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FOXD2 TRIM63 NOTCH2	6.47e-04	168	45	3	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 DLL4 MUC5AC	6.58e-04	169	45	3	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	wk_15-18-Hematologic-Meg-ery-Megakaryocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MED12L SELP ITGB3	6.58e-04	169	45	3	d571e84e01e3316748d4407ed98881b17484e035
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MED12L SELP ITGB3	6.69e-04	170	45	3	3886a77bc3ddbeb42a8149b759fe578871676d6e
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MED12L SELP ITGB3	6.69e-04	170	45	3	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 PAQR5 SLC13A2	6.69e-04	170	45	3	75b0486620cab838d3feb1c3aa965b487a906618
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 KIF5A MUC5AC	6.69e-04	170	45	3	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 KIF5A MUC5AC	6.69e-04	170	45	3	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 SEC24D KIF5A	6.81e-04	171	45	3	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	wk_08-11-Hematologic-Meg-ery-Megakaryocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MED12L SELP ITGB3	6.81e-04	171	45	3	9dda25df493766723335851b3c3d89735b6e8051
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 KIF5A DLL4	6.81e-04	171	45	3	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAQR5 SEC24D KIF5A	6.81e-04	171	45	3	2dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 SEC24D KIF5A	6.81e-04	171	45	3	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAQR5 SEC24D KIF5A	6.81e-04	171	45	3	2aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAQR5 KIF5A MUC5AC	6.92e-04	172	45	3	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MED12L SELP ITGB3	6.92e-04	172	45	3	e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MED12L SELP ITGB3	6.92e-04	172	45	3	bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCell	Immune-mast_cell\|World / Lineage, Cell type, age group and donor	MED12L SELP TRIM63	6.92e-04	172	45	3	6e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAQR5 KIF5A MUC5AC	6.92e-04	172	45	3	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MED12L SELP ITGB3	6.92e-04	172	45	3	875ea290840e835952623b905eb610f3c71456d2
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 SEC24D DLL4	6.92e-04	172	45	3	30916a902c151907745756d14327e24adc34afef
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 SEC24D KIF5A	7.04e-04	173	45	3	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 SEC24D KIF5A	7.04e-04	173	45	3	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FGB SLC13A2 MUC5AC	7.16e-04	174	45	3	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FGB SLC13A2 MUC5AC	7.16e-04	174	45	3	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D ATRNL1 NOTCH2	7.28e-04	175	45	3	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D ATRNL1 NOTCH2	7.28e-04	175	45	3	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 PLXNA3 SPRY4	7.28e-04	175	45	3	1d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MED12L SELP ITGB3	7.28e-04	175	45	3	b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 PLXNA3 SPRY4	7.28e-04	175	45	3	d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 XPNPEP2 SLC13A2	7.40e-04	176	45	3	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	SEC24D ITGB3 NOTCH2	7.40e-04	176	45	3	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	356C-Endothelial_cells-Endothelial-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELP DLL4 ITGB3	7.52e-04	177	45	3	a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXD2 PAQR5 ZBTB16	7.52e-04	177	45	3	baf78a8dad55f124f56585f88b10b58c0269680f
ToppCell	(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(1)_Control_(PBS) / Stress and Cell class	LRP1 ZBTB16 ITGB3	7.52e-04	177	45	3	d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCell	3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho\|lymph-node_spleen / Manually curated celltypes from each tissue	LRP1 FAM219A NPNT	7.52e-04	177	45	3	53040dbeb18574a48e352e4bce252c7c3018762c
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB16 P2RX7 LPAR6	7.52e-04	177	45	3	dba8b30a311051c22ca5f77697f5dbf9423c3ba0
ToppCell	356C-Endothelial_cells-Endothelial-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELP DLL4 ITGB3	7.52e-04	177	45	3	ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MED12L SELP ITGB3	7.65e-04	178	45	3	5caeffb70cbb868586bd260b44ccd3751bbfa615
Drug	Dmp 728	SELP FGB ITGB3	3.23e-06	15	45	3	CID000121844
Drug	alpha-quarterthiophene	SELP TSC2 ITGB3	5.77e-06	18	45	3	CID000395493
Drug	25-hydroxycholesterol	LRP1 LRP2 FGB CGB2 NOTCH2	1.57e-05	160	45	5	CID000065094
Drug	MF I	LRP1 SELP LRP2 TRIM63 ITGB3	1.71e-05	163	45	5	CID000007871
Drug	c7E3	SELP FGB ITGB3	2.04e-05	27	45	3	CID003413300
Drug	N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate	SELP ITGB3	2.29e-05	4	45	2	ctd:C111914
Drug	Ro 44-9883	SELP FGB ITGB3	3.12e-05	31	45	3	CID000071453
Drug	aurin	SELP FGB ITGB3	3.44e-05	32	45	3	CID000005100
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	SEC24D KIF5A ITGB3 MUC5AC SIPA1L3	3.76e-05	192	45	5	6512_UP
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SLC12A8 IL4R ZMYM6 NOTCH2 SIPA1L3	4.15e-05	196	45	5	5350_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	PAQR5 SEC24D IRS4 ATRNL1 DOP1B	4.25e-05	197	45	5	4120_UP
Drug	Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A	LRP1 KIF5A NUP188 NOTCH2 DOP1B	4.25e-05	197	45	5	3000_UP
Drug	Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A	LRP2 KIF5A IRS4 NUP188 ITGB3	4.36e-05	198	45	5	3367_UP
Drug	Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A	LRP1 SELP FGB SLC12A8 DOP1B	4.46e-05	199	45	5	2985_UP
Drug	Integrilin	SELP FGB ITGB3	5.35e-05	37	45	3	CID000123610
Drug	K-S-L	SELP ITGB3 MUC5AC	6.27e-05	39	45	3	CID000484125
Drug	rhamnose	SELP FGB ITGB3 MUC5AC IL4R NOTCH2	6.82e-05	356	45	6	CID000000840
Drug	trisodium citrate dihydrate	SELP FGB SLC13A2	7.85e-05	42	45	3	CID000071474
Drug	CID5311082	SELP FGB ITGB3	8.42e-05	43	45	3	CID005311082
Drug	cangrelor	SELP ITGB3	1.06e-04	8	45	2	ctd:C117446
Drug	Aspirin, Dipyridamole Drug Combination	SELP ITGB3	1.06e-04	8	45	2	ctd:D000068342
Drug	efegatran	SELP ITGB3	1.06e-04	8	45	2	CID000060781
Drug	coprogen	LRP1 LRP2	1.36e-04	9	45	2	CID006323272
Drug	Adenosine Diphosphate	SELP FGB ITGB3	1.41e-04	51	45	3	ctd:D000244
Disease	myocardial infarction (is_implicated_in)	LRP1 SELP FGB ITGB3	1.21e-05	99	42	4	DOID:5844 (is_implicated_in)
Disease	IGF-1 measurement	FGB TRIM63 P2RX7 IL4R SENP7 DOP1B	6.28e-05	488	42	6	EFO_0004627
Disease	pancreatic ductal carcinoma (is_marker_for)	TSC2 MUC5AC IL4R	9.11e-05	61	42	3	DOID:3587 (is_marker_for)
Disease	Inhalant adrenergic use measurement	MUC5AC IL4R SPRY4	3.49e-04	96	42	3	EFO_0009941
Disease	Unipolar Depression	LRP1 SELP ZBTB16 SEC24C	4.99e-04	259	42	4	C0041696
Disease	Sjogren's syndrome (is_marker_for)	SELP MUC5AC	5.35e-04	24	42	2	DOID:12894 (is_marker_for)
Disease	atopic dermatitis (is_implicated_in)	SELP IL4R	6.29e-04	26	42	2	DOID:3310 (is_implicated_in)
Disease	adult onset asthma	LRP1 MUC5AC IL4R	6.39e-04	118	42	3	EFO_1002011
Disease	asthma	LRP1 MUC5AC IL4R SPRY4 SENP7 NPNT	6.40e-04	751	42	6	MONDO_0004979
Disease	hyperuricemia	LRP2 SIPA1L3	1.02e-03	33	42	2	EFO_0009104
Disease	respiratory system disease	MUC5AC IL4R NPNT	1.16e-03	145	42	3	EFO_0000684

Protein segments in the cluster

Peptide	Gene	Start	Entry
TESCGIMYTKCTCPQ	ADGRB3	186	O60242
SAICSPRDSMYQSVC	DLL4	656	Q9NR61
VYMCTSCVYPLVSSC	PAQR5	86	Q9NXK6
STCIDRVASFSCMCP	NOTCH2	351	Q04721
VYGLSCMLQTVTLCC	MED12L	361	Q86YW9
SCSSALTCSMANCQY	NPNT	126	Q6UXI9
CLPTSETTRSCMCTA	LRP1	1861	Q07954
SLMTICCCVTDCYLQ	DOP1B	796	Q9Y3R5
VSAQMEYCRTPCTVS	FGB	216	P02675
YNCSVLQSCMSCVGS	PLXNA3	636	P51805
SVNPTCMCCQATSST	FAM219A	166	Q8IW50
MTCCQTSFCGYPSCS	KRTAP1-3	1	Q8IUG1
TMYPITLCIAVSNCC	LPAR6	271	P43657
TYCMPMCSSTQFLCA	LRP2	3506	P98164
SCHTLDMTCYSPQCV	MUC5AC	826	P98088
CNPLLYTVTMSCQVC	OR8B12	126	Q8NGG6
MPACCSCSDVFQYET	P2RX7	1	Q99572
TVNTTICAGYCPTMT	CGB2	46	Q6NT52
EPTCVSDYMSISTCE	IL4R	31	P24394
CTTSVSVPSQVYCEC	ATRNL1	221	Q5VV63
ALCYTASCQDMSCSK	SELP	156	P16109
GYYCNCTTRTDTCMS	ITGB3	581	P05106
CRTTMFICCSPSSYN	KIF5A	296	Q12840
CQTSYVESSPCQTSC	KRTAP13-1	66	Q8IUC0
CQTSYVESSPCQTSC	KRTAP13-2	66	Q52LG2
CTSYNIPCTSDMAKQ	SEC24C	376	P53992
SYFSLSMCSCSLTPV	SLC12A8	401	A0AV02
HLTQCMSLCVCYSAS	SLC13A2	216	Q13183
FSECCMDISLSPSRC	IRS4	1051	O14654
CCCEIMSSESSPAAL	FOXD2	6	O60548
ITCESVQMSSELCPY	SENP7	486	Q9BQF6
CLCSAQTLVNYGTCM	SPRY4	186	Q9C004
SITCSSTMSYSCCLP	KRT34	36	O76011
PCTDNVCYSMAVTRS	SIPA1L3	756	O60292
FIRCTTYCFPCTSDM	SEC24D	311	O94855
NIYCLTCEVPTCSMC	TRIM63	131	Q969Q1
QCTICTEYCPSLSSM	ZBTB16	631	Q05516
QSNDYISPMCSCSSE	FGD6	101	Q6ZV73
DCTTSTACMCVYGLL	NUP188	371	Q5SRE5
KMCSYCSQTSPNLVE	ZMYM6	516	O95789
TLSYLNSSCTGPMCV	XPNPEP2	286	O43895
YCCSISPDCSMLCSA	WSB2	201	Q9NYS7
TPSCSEMLTYRCSGC	TERB1	581	Q8NA31
LPETDYECTNSTSCM	TM2D3	131	Q9BRN9
YECTNSTSCMTVSCP	TM2D3	136	Q9BRN9
SPCSVDQLCSALCSM	TSC2	726	P49815