Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	microtubule organizing center	PDE4B BRSK2 SCYL1 TOGARAM1 SPPL2B SKI ACTR1B TTBK2 RGS14 FBXW8 KIF15 CTDP1 PKHD1 FLCN SAC3D1 CEP131 EMD	1.20e-04	919	138	17	GO:0005815
GeneOntologyCellularComponent	KICSTOR complex	ITFG2 SZT2	2.57e-04	4	138	2	GO:0140007
Domain	Dapper	DACT1 DACT3	1.71e-04	3	142	2	PF15268
Domain	ASD1	SHROOM3 SHROOM2	1.71e-04	3	142	2	PF08688
Domain	ASD1_dom	SHROOM3 SHROOM2	1.71e-04	3	142	2	IPR014800
Domain	Dapper	DACT1 DACT3	1.71e-04	3	142	2	IPR024843
Domain	ASD1	SHROOM3 SHROOM2	1.71e-04	3	142	2	PS51306
Domain	Shroom_fam	SHROOM3 SHROOM2	3.41e-04	4	142	2	IPR027685
Domain	ASD2_dom	SHROOM3 SHROOM2	3.41e-04	4	142	2	IPR014799
Domain	ASD2	SHROOM3 SHROOM2	3.41e-04	4	142	2	PF08687
Domain	REJ	PKDREJ PKD1	3.41e-04	4	142	2	PS51111
Domain	ASD2	SHROOM3 SHROOM2	3.41e-04	4	142	2	PS51307
Domain	REJ_dom	PKDREJ PKD1	3.41e-04	4	142	2	IPR014010
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCL SEMA4F SHROOM3 SPIRE2 B4GALNT4 TRIO SZT2 FBRSL1 SPPL2B FHIP1B PLEKHG5 ITGB4 TFE3 PPP1R26 DACT1 ARHGEF40 PTPRF CELSR2 MROH6 ADAMTS7 PLEKHO2 CD2BP2 PKD1 CTDP1 FLCN SAC3D1 CACNA1H CEP131 MMP17	3.54e-15	1105	148	29	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	IQSEC3 SHROOM3 PDE4B AKAP8 TRIO DIDO1 LMTK3 MAP7D1 CELSR2 KIF15 FAM171A2 ICAM5 DCHS1 CEP131 BSN GOLGA2 TP53BP1 TPD52L2 ANKS1A	3.12e-08	963	148	19	28671696
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 AKAP8 LRRK2 SCYL1 SNAP47 TTN USP19 KIAA1671 DENND6A FAM171A2 GLI3 CEP131 EMD TPD52L2	6.41e-06	777	148	14	35844135
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SHROOM3 SZT2 FBRSL1 DIDO1 SRCIN1 PLEKHG5 RPRD2 BSN KDM4B ANKS1A ZNF646	1.78e-05	529	148	11	14621295
Pubmed	Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort.	SHROOM3 SHROOM2	1.80e-05	2	148	2	29423651
Pubmed	Pathogenicity analysis of novel variations in Chinese Han patients with polycystic kidney disease.	PKD1 PKHD1	1.80e-05	2	148	2	28578020
Pubmed	The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.	PKD1 PKHD1	1.80e-05	2	148	2	11919560
Pubmed	Detailed haplotype-tagging study of germline variation of MUC19 in inflammatory bowel disease.	LRRK2 MUC19	1.80e-05	2	148	2	19714762
Pubmed	The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.	TRIO PTPRF	1.80e-05	2	148	2	8643598
Pubmed	Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.	TFE3 FLCN	1.80e-05	2	148	2	27095138
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	SPIRE2 TRIO SRCIN1 PPP1R26 ACTR1B GARIN3 C17orf75 RPRD2 CEP131 TAF10 MMP17 ZNF646	4.18e-05	689	148	12	36543142
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	DIDO1 PLEKHG5 ITGB4 ADCY3 USP19 MAP7D1 ICAM5 AGL PKD1 CTDP1 CEP131 EMD GTPBP3 ZNF598	4.39e-05	925	148	14	28986522
Pubmed	Characterization of PKD protein-positive exosome-like vesicles.	PKD1 PKHD1	5.38e-05	3	148	2	19158352
Pubmed	Analysis of the polycystin complex (PCC) in human urinary exosome-like vesicles (ELVs).	PKD1 PKHD1	5.38e-05	3	148	2	32001768
Pubmed	The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.	TFE3 FLCN	5.38e-05	3	148	2	27913603
Pubmed	Expression of polycystins and fibrocystin on primary cilia of lung cells.	PKD1 PKHD1	5.38e-05	3	148	2	25367197
Pubmed	Three Dact gene family members are expressed during embryonic development and in the adult brains of mice.	DACT1 DACT3	5.38e-05	3	148	2	16881060
Pubmed	Dact1-3 mRNAs exhibit distinct expression domains during tooth development.	DACT1 DACT3	5.38e-05	3	148	2	20170752
Pubmed	TFEB and TFE3 drive kidney cystogenesis and tumorigenesis.	TFE3 FLCN	5.38e-05	3	148	2	36987696
Pubmed	Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis.	PKD1 PKHD1	5.38e-05	3	148	2	37845212
Pubmed	The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins.	TTN MYOM2	5.38e-05	3	148	2	7505783
Pubmed	A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity.	TFE3 FLCN	5.38e-05	3	148	2	32049013
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	NRBP1 AKAP8 MAN1C1 DIDO1 ITGB4 CTDP1 RPRD2 CEP131 GOLGA2 TP53BP1	6.30e-05	503	148	10	16964243
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SEMA4F RGL3 LMTK3 SHROOM2 MAP7D1 GLI3 BSN	6.64e-05	233	148	7	37704626
Pubmed	FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues.	GDF7 GLI3 PAX1	8.16e-05	20	148	3	15105374
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	CACNA1S SHROOM3 SCYL1 LMTK3 TTN RNF115 KIAA1671 BSN RUNDC1	1.00e-04	430	148	9	35044719
Pubmed	Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.	TFE3 FLCN	1.07e-04	4	148	2	35420934
Pubmed	Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy.	ISLR DACT1	1.07e-04	4	148	2	30510196
Pubmed	Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.	TFE3 FLCN	1.07e-04	4	148	2	30843872
Pubmed	Cilia and polycystic kidney disease.	PKD1 PKHD1	1.07e-04	4	148	2	32475690
Pubmed	Loss of oriented cell division does not initiate cyst formation.	PKD1 PKHD1	1.07e-04	4	148	2	19959710
Pubmed	A new standard nomenclature for proteins related to Apx and Shroom.	SHROOM3 SHROOM2	1.07e-04	4	148	2	16615870
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	ADCY3 PKD1 PKHD1	1.62e-04	25	148	3	28154160
Pubmed	A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.	PKD1 PKHD1	1.78e-04	5	148	2	21685914
Pubmed	Polycystin channels and kidney disease.	PKDREJ PKD1	1.78e-04	5	148	2	11698076
Pubmed	Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.	PKD1 GOLGA2	1.78e-04	5	148	2	11901144
Pubmed	Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.	PTPRF BSN	1.78e-04	5	148	2	22357843
Pubmed	Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1.	PKD1 FLCN	1.78e-04	5	148	2	36794754
Pubmed	Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.	TFE3 FLCN	1.78e-04	5	148	2	21209915
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	OTUD5 FBRSL1 KIAA1671 KIF15 CD2BP2 CEP131 BSN GOLGA2 ZMYM3 TP53BP1	2.24e-04	588	148	10	38580884
Pubmed	Establishment of cardiac cytoarchitecture in the developing mouse heart.	TTN MYOM2	2.67e-04	6	148	2	16337936
Pubmed	Genetic and molecular control of folate-homocysteine metabolism in mutant mice.	SKI GLI3	2.67e-04	6	148	2	12016514
Pubmed	Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis.	PDGFB PAX1	2.67e-04	6	148	2	7743923
Pubmed	Expression of nerve-regulated genes in muscles of mouse mutants affected by spinal muscular atrophies and muscular dystrophies.	SCYL1 TTN	2.67e-04	6	148	2	9040657
Pubmed	Loss of polycystin-1 inhibits Bicc1 expression during mouse development.	PKD1 PKHD1	2.67e-04	6	148	2	24594709
Pubmed	Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice.	DACT1 PAX1	2.67e-04	6	148	2	20145239
Pubmed	Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.	TP53BP1 CRB2	2.67e-04	6	148	2	17190600
Pubmed	Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.	PKD1 PKHD1	2.67e-04	6	148	2	17575307
Pubmed	Tulp3 Is a Ciliary Trafficking Gene that Regulates Polycystic Kidney Disease.	ADCY3 PKD1	2.67e-04	6	148	2	30799240
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SHROOM3 SPIRE2 AKAP8 TRIO BRSK2 KIAA1671 MAP7D1 MYLK3 FAM171A2 CEP131 ZNF598 ANKS1A	3.32e-04	861	148	12	36931259
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ALLC TRIO LRRK2 ITGB4 FAM83C KIF15 CACNA1H EMD CAPN15	3.70e-04	513	148	9	25798074
Pubmed	The GTPase-deficient Rnd proteins are stabilized by their effectors.	PLEKHG5 RGS14	3.72e-04	7	148	2	22807448
Pubmed	Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.	CELSR2 ADAMTS7	3.72e-04	7	148	2	21239051
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1S CACNA1H	3.72e-04	7	148	2	12900400
Pubmed	Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.	GDF7 PAX1	3.72e-04	7	148	2	8145850
Pubmed	Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.	SKI GLI3	3.72e-04	7	148	2	12435627
Pubmed	The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin.	ITGB4 RAPGEF3	3.72e-04	7	148	2	15302884
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IQSEC3 FHIP1B ADCY3 USP19 MAP7D1 PLCL2 CACNA1H ZMYM3	3.72e-04	407	148	8	12693553
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	TRIO EMD ZNF598 TP53BP1	3.87e-04	80	148	4	16094384
Pubmed	Human transcription factor protein interaction networks.	AKAP8 FBRSL1 DIDO1 SKI TTN TFE3 KIAA1671 MAP7D1 GLI3 CD2BP2 RPRD2 CEP131 EMD TAF10 ZMYM3 TP53BP1	4.05e-04	1429	148	16	35140242
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	FHIP1B TTN ADCY3 TFE3 FBXW8 MAP7D1 GLI3	4.71e-04	321	148	7	32098917
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RGL3 ARHGEF40 DENND6A ZNF598	4.88e-04	85	148	4	15449545
Pubmed	All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases.	DACT1 DACT3	4.95e-04	8	148	2	21718540
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1S CACNA1H	4.95e-04	8	148	2	28330839
Pubmed	The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity.	PKD1 PKHD1	4.95e-04	8	148	2	20215348
Pubmed	The interfrontal bone and mutant genes in the mouse.	GLI3 PAX1	4.95e-04	8	148	2	1018005
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	AKAP8 OTUD5 DIDO1 USP19 CTDP1 SAC3D1 ZMYM3 KDM4B TP53BP1 ANKS1A MPG	5.01e-04	774	148	11	15302935
Pubmed	Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.	SHROOM2 GOLGA2 CRB2	5.28e-04	37	148	3	25742799
Pubmed	Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton.	GLI3 PAX1	6.35e-04	9	148	2	9256352
Pubmed	Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.	TFE3 FLCN	6.35e-04	9	148	2	23582324
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1S CACNA1H	6.35e-04	9	148	2	16382099
Pubmed	Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes.	GLI3 PAX1	6.35e-04	9	148	2	15728667
Pubmed	Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.	PKD1 PKHD1	6.35e-04	9	148	2	18172001
Pubmed	Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.	SHROOM3 SHROOM2	6.35e-04	9	148	2	17666436
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SHROOM3 SCYL1 SRCIN1 TTN KIAA1671 PLEKHO2 EMD GOLGA2 TPD52L2	7.37e-04	565	148	9	25468996
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	IQSEC3 TMEM121B BRSK2 BCAN SRCIN1 LMTK3 BSN	7.45e-04	347	148	7	17114649
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	ZIC5 GLI3	7.91e-04	10	148	2	18298960
Pubmed	Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.	PKDREJ PKD1	7.91e-04	10	148	2	16805797
Pubmed	Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.	GLI3 PAX1	7.91e-04	10	148	2	14602680
Pubmed	Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.	MYCL PDGFB	7.91e-04	10	148	2	8406449
Pubmed	Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain.	ZIC5 GLI3	7.91e-04	10	148	2	15736266
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	NRBP1 LMTK3 USP19 RGS14 FBXW8 KIF15	8.44e-04	257	148	6	30945288
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SEMA4F TRIO MEX3A CELSR2 GLI3 RPRD2 GDF11	8.93e-04	358	148	7	32460013
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TTN KIAA1671 GLI3 EMD GOLGA2 ANKS1A	9.51e-04	263	148	6	34702444
Pubmed	Reprogramming tumour-associated macrophages to outcompete cancer cells.	TFE3 FLCN	9.65e-04	11	148	2	37380769
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	TRIO DIDO1 RPRD2 CEP131 EMD GOLGA2 TP53BP1 MPG	9.77e-04	472	148	8	38943005
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	NRBP1 GTPBP3 RUNDC1 CRB2	1.00e-03	103	148	4	29539633
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ALLC AKAP8 SKI FBXW8 MAP7D1 NACC2 AGL TAF10 ZNF598 ZMYM3 TP53BP1	1.15e-03	857	148	11	25609649
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	BSN TP53BP1	1.15e-03	12	148	2	28700933
Pubmed	Molecular diversity of myofibrillar proteins: gene regulation and functional significance.	TTN MYOM2	1.15e-03	12	148	2	8618961
Pubmed	Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.	GLI3 PAX1	1.15e-03	12	148	2	20627960
Pubmed	A whole genome screen for HIV restriction factors.	RAPGEF3 RPRD2 RAB37 B4GALT3	1.20e-03	108	148	4	22082156
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	AKAP8 SZT2 DNAJC30 SNAP47 KIAA1671 MAP7D1 C17orf75 AGL GTPBP3	1.20e-03	606	148	9	36538041
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	IQSEC3 TRIO BRSK2 SRCIN1 SHROOM2 SNAP47 CELSR2 FAM171A2 CEP131 EMD BSN TP53BP1 TPD52L2	1.21e-03	1139	148	13	36417873
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	AKAP8 DIDO1 SKI TTN TFE3 MAP7D1 ZIC5 CD2BP2 RPRD2 TIGD5 EMD TAF10 ZMYM3 MPG	1.30e-03	1294	148	14	30804502
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	TOPAZ1 SRCIN1 MEI1 MAP7D1 KIF15 MYOM2 GOLGA2 KDM4B	1.36e-03	497	148	8	36774506
Pubmed	Szt2, a novel gene for seizure threshold in mice.	SZT2 PTPRF	1.36e-03	13	148	2	19624305
Pubmed	Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.	COL20A1 PKDREJ MARCHF11	1.51e-03	53	148	3	27357688
Pubmed	Loss of Gli3 and Shh function disrupts olfactory axon trajectories.	ADCY3 GLI3	1.58e-03	14	148	2	15065125
Pubmed	Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.	GLI3 DCHS1	1.58e-03	14	148	2	32151560
Interaction	TOP3B interactions	MYCL SEMA4F SHROOM3 SPIRE2 B4GALNT4 TRIO SZT2 FBRSL1 SPPL2B FHIP1B PLEKHG5 ITGB4 TFE3 PPP1R26 ACTR1B DACT1 ARHGEF40 PTPRF CELSR2 MROH6 ADAMTS7 PLEKHO2 CD2BP2 PKD1 CTDP1 FLCN SAC3D1 CACNA1H CEP131 ZNF598 MMP17 TP53BP1	1.05e-08	1470	144	32	int:TOP3B
Cytoband	16p13.3	ZNF213 DNAAF8 PKD1 CACNA1H PGP ZNF598 CAPN15 MPG	1.41e-06	244	148	8	16p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	ZNF213 DNAAF8 PKD1 CACNA1H PGP ZNF598 CAPN15 MPG	7.83e-05	426	148	8	chr16p13
Cytoband	3p21.31	TOPAZ1 USP19 KIF15 BSN	3.20e-04	100	148	4	3p21.31
Cytoband	20p11.2	INSM1 PAX1	5.57e-04	11	148	2	20p11.2
Cytoband	1q21-q23	INSRR B4GALT3	7.87e-04	13	148	2	1q21-q23
GeneFamily	Fibronectin type III domain containing	COL20A1 INSRR TTN ITGB4 PTPRF MYOM2	1.39e-04	160	89	6	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	TRIO ISLR TTN PTPRF MYOM2	1.20e-03	161	89	5	593
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	TRIO INSM1 BRSK2 MEX3A PTPRF CELSR2 GRIN3A RAB37 KDM4B	2.43e-08	200	148	9	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ALLC OTUD5 MUC19 TMEM119 DACT1 MROH6 DACT3 CEP131	3.08e-08	145	148	8	07acbf086cffce0628accf078d31bf190f803988
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYCL CACNA1S TMEM121B SRCIN1 MEX3A DACT3 SCT	1.86e-06	173	148	7	b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCell	mLN-(5)_Dendritic_cell-(54)_pDC\|mLN / shred on region, Cell_type, and subtype	MYCL IQSEC3 BCAN SHROOM2 ICAM5 SCT REPS2	4.70e-06	199	148	7	1e738219784a446ee8b0ddeb408e0050e1929e60
ToppCell	mLN-Dendritic_cell-pDC\|mLN / Region, Cell class and subclass	MYCL IQSEC3 BCAN SHROOM2 ICAM5 SCT REPS2	4.70e-06	199	148	7	54f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	TTN FAM83C MYLK3 KCNS1 RAB37	1.07e-05	87	148	5	fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAP25 TRIO COL20A1 TMEM121B REPS2 ZNF598	1.49e-05	158	148	6	12661763d1c309106801cb710c04cd2b62d16cba
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAP25 TRIO COL20A1 TMEM121B REPS2 ZNF598	1.49e-05	158	148	6	e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAP25 TRIO COL20A1 TMEM121B REPS2 ZNF598	1.49e-05	158	148	6	0792c39e6fc0745095af7812de2d50949540d60f
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TMEM121B LRRK2 MEI1 RGS14 ICAM5 KCNS1	1.66e-05	161	148	6	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GDF7 DCHS1 GRIN3A RAB37 OC90	1.82e-05	97	148	5	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	AKAP8 SZT2 USP19 PTPRF RPRD2 ANKS1A	1.97e-05	166	148	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ALLC MUC19 DACT1 MROH6 DACT3 ZNF598	1.97e-05	166	148	6	c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SAP25 ISLR MROH6 MRPL36 ZNF853 B4GALT3	2.65e-05	175	148	6	3031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PDE4B COL20A1 INSM1 SRCIN1 KCNS1 MMP17	2.83e-05	177	148	6	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F SAP25 COL20A1 BRSK2 SRCIN1 PPP1R26	2.92e-05	178	148	6	3e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE4B COL20A1 INSM1 BRSK2 MARCHF11 MMP17	3.01e-05	179	148	6	df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL20A1 INSM1 BCAN SRCIN1 CELSR2 MMP17	3.30e-05	182	148	6	d6740bca2b974122b8451989365a94a81140afd1
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE4B COL20A1 NAT16 INSM1 SRCIN1 MMP17	3.30e-05	182	148	6	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F SPIRE2 COL20A1 BRSK2 SRCIN1 ITGB4	3.30e-05	182	148	6	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAN1C1 INSM1 INSRR ZNF446 PPP1R26 CACNA1H	3.30e-05	182	148	6	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAN1C1 INSM1 INSRR ZNF446 PPP1R26 CACNA1H	3.30e-05	182	148	6	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INSRR ISLR DACT1 GLI3 CACNA1H GRIN3A	3.62e-05	185	148	6	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE4B COL20A1 INSM1 BRSK2 SRCIN1 MMP17	3.62e-05	185	148	6	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL20A1 INSM1 BCAN MEX3A FAM171A2 ZNF853	3.73e-05	186	148	6	10565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE4B COL20A1 INSM1 BCAN CELSR2 MMP17	3.73e-05	186	148	6	76535681667c8afb884fa72b6edfee9e1e46335b
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PDE4B COL20A1 INSM1 BRSK2 SRCIN1 MMP17	3.84e-05	187	148	6	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	3.84e-05	187	148	6	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	3.84e-05	187	148	6	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1S ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.20e-05	190	148	6	78cc6c28b31de041c24175a98f47da256ecc15a2
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.20e-05	190	148	6	5c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.20e-05	190	148	6	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1S ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.20e-05	190	148	6	e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.20e-05	190	148	6	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.45e-05	192	148	6	f7e4509003d71f805b9d4587098e90d2897b6739
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM3 RGL3 LRRK2 TTN CELSR2 PKHD1	4.45e-05	192	148	6	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.45e-05	192	148	6	705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT4 TMEM121B SRCIN1 CELSR2 ICAM5 BSN	4.58e-05	193	148	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.58e-05	193	148	6	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RGL3 ITGB4 ZIC5 RAPGEF3 PLEKHO2 GLI3	4.58e-05	193	148	6	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT4 TMEM121B SRCIN1 CELSR2 ICAM5 BSN	4.58e-05	193	148	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT4 TMEM121B SRCIN1 CELSR2 ICAM5 BSN	4.58e-05	193	148	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE4B COL20A1 INSM1 BCAN CELSR2 MMP17	4.58e-05	193	148	6	cdc44bf6f5436eb8a2d4720fe011dcb85ccecf87
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	SHROOM3 BCAN KIF15 NACC2 GLI3 CRB2	5.14e-05	197	148	6	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	SHROOM3 BCAN KIF15 NACC2 GLI3 CRB2	5.14e-05	197	148	6	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGB4 ADCY3 DACT1 ZNF853 GDF11 CAPN15	5.43e-05	199	148	6	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BRSK2 PLEKHG5 ZNF446 USP19 CELSR2 PKHD1	5.43e-05	199	148	6	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	AKAP8 ZNF213 CD2BP2 RUNDC1 TPD52L2 ZNF646	5.58e-05	200	148	6	ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	OTUD5 INSM1 MEI1 SKI SHROOM2 CTDP1	5.58e-05	200	148	6	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	TCGA-Bile_Duct-Primary_Tumor\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	AKAP8 ZNF213 CD2BP2 RUNDC1 TPD52L2 ZNF646	5.58e-05	200	148	6	0350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DACT1 GDF7 NACC2 GRIN3A NPAS1	1.32e-04	147	148	5	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DACT1 GDF7 NACC2 GRIN3A RAB37	1.36e-04	148	148	5	4d43efee96a6493abd78e9ca41aab73db0c80626
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	BRSK2 LMTK3 PKDREJ TTN DACT1	1.36e-04	148	148	5	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	BRSK2 LMTK3 PKDREJ TTN DACT1	1.36e-04	148	148	5	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
Disease	Craniorachischisis	SKI DACT1 ZIC5 GLI3	1.02e-05	29	139	4	C0152426
Disease	Neural Tube Defects	SHROOM3 SKI ZIC5 GLI3	1.17e-05	30	139	4	C0027794
Disease	Cyst	PKD1 FLCN	2.20e-05	2	139	2	C0010709
Disease	smoking cessation	PDE4B MEI1 USP19 PTPRF ADAMTS7 PLCL2 CACNA1H BSN ANKS1A	2.50e-05	325	139	9	EFO_0004319
Disease	Small cell carcinoma of lung	MYCL INSM1 TTN TTBK2	1.24e-04	54	139	4	C0149925
Disease	Choledochal Cyst, Type I	PKHD1 SCT	2.18e-04	5	139	2	C0009439
Disease	Choledochal Cyst, Type II	PKHD1 SCT	2.18e-04	5	139	2	C1257796
Disease	Choledochal Cyst, Type III	PKHD1 SCT	2.18e-04	5	139	2	C1257797
Disease	Choledochal Cyst, Type IV	PKHD1 SCT	2.18e-04	5	139	2	C1257798
Disease	Choledochal Cyst, Type V	PKHD1 SCT	2.18e-04	5	139	2	C1257799
Disease	Choledochal Cyst	PKHD1 SCT	2.18e-04	5	139	2	C0008340
Disease	Iniencephaly	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0152234
Disease	Acrania	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0702169
Disease	Tethered Cord Syndrome	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0080218
Disease	Spinal Cord Myelodysplasia	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0344479
Disease	Exencephaly	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0266453
Disease	Neurenteric Cyst	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0027806
Disease	Diastematomyelia	SKI ZIC5 GLI3	3.07e-04	28	139	3	C0011999
Disease	Ovarian Mucinous Adenocarcinoma	NRBP1 LRRK2 TTN	4.17e-04	31	139	3	C1335167
Disease	Parkinson disease	LRRK2 FBRSL1 MUC19 SPPL2B FAM171A2 MRPL36 ZNF646	8.47e-04	321	139	7	MONDO_0005180
Disease	Crohn's disease	NRBP1 C10orf55 PDGFB LRRK2 MUC19 ADCY3 RGS14 BSN	1.20e-03	441	139	8	EFO_0000384
Disease	Congenital myopathy (disorder)	CACNA1S TTN	1.41e-03	12	139	2	C0270960
Disease	cannabis dependence measurement	MEI1 PKHD1 PAX1	1.52e-03	48	139	3	EFO_0008457
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	PKHD1 MRPL36	1.66e-03	13	139	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	Connective Tissue Diseases	PKD1 FLCN	1.66e-03	13	139	2	C0009782
Disease	triglycerides to total lipids in large LDL percentage	PRKAG3 CELSR2 TP53BP1	1.81e-03	51	139	3	EFO_0022331
Disease	Metastatic melanoma	TRIO SCYL1 TTN	2.13e-03	54	139	3	C0278883
Disease	vital capacity	CACNA1S SHROOM3 PDGFB SKI TTN ADCY3 FBXW8 GLI3 SLBP RPRD2 NEURL1B ZNF853 KDM4B ANKS1A	2.14e-03	1236	139	14	EFO_0004312
Disease	cortical thickness	SHROOM3 SPIRE2 ACTR1B DACT1 ARHGEF40 PTPRF ADAMTS7 GLI3 PKD1 PKHD1 KDM4B CRB2 ANKS1A	2.37e-03	1113	139	13	EFO_0004840
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	PKD1 PKHD1	2.53e-03	16	139	2	DOID:0110861 (implicated_via_orthology)
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 PRKAG3 CELSR2 TP53BP1	2.62e-03	121	139	4	EFO_0008595, EFO_0020943
Disease	creatinine measurement	NRBP1 CACNA1S SHROOM3 SPIRE2 TTN RGS14 CELSR2 ADAMTS7 PKHD1 MRPL36 BSN REPS2	2.68e-03	995	139	12	EFO_0004518
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO KDM4B	2.86e-03	17	139	2	DOID:0060307 (is_implicated_in)
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 PRKAG3 CELSR2 TP53BP1	3.12e-03	127	139	4	EFO_0008595, EFO_0020947
Disease	triglycerides to total lipids in IDL percentage	PRKAG3 CELSR2 TP53BP1	3.30e-03	63	139	3	EFO_0022329
Disease	cholesterol to total lipids in medium VLDL percentage	PRKAG3 CELSR2 TP53BP1	3.30e-03	63	139	3	EFO_0022239
Disease	triglycerides in small LDL measurement	PRKAG3 CELSR2 TP53BP1	3.61e-03	65	139	3	EFO_0022323
Disease	cardiac troponin T measurement	CACNA1S TRIO TXLNB GLI3 PKHD1	3.87e-03	219	139	5	EFO_0005043
Disease	cholesterol to total lipids in very small VLDL percentage	PRKAG3 CELSR2 TP53BP1	3.93e-03	67	139	3	EFO_0022245
Disease	renal system measurement	SHROOM3 RGS14	3.96e-03	20	139	2	EFO_0004742
Disease	dilated cardiomyopathy	TTN PKD1	3.96e-03	20	139	2	EFO_0000407
Disease	reaction time measurement	AKAP8 TOPAZ1 LRRK2 FBRSL1 MUC19 PKHD1 GRIN3A GTPBP3 OC90	4.07e-03	658	139	9	EFO_0008393
Disease	serum gamma-glutamyl transferase measurement	DNAJC30 SKI COA8 CELSR2 PKD1 PKHD1 SLBP NDUFAF6 PGP MMP17 TP53BP1	4.08e-03	914	139	11	EFO_0004532
Disease	triglycerides to total lipids in very small VLDL percentage	PRKAG3 CELSR2 TP53BP1	4.27e-03	69	139	3	EFO_0022341
Disease	stroke, coronary artery disease	CELSR2 ADAMTS7	4.36e-03	21	139	2	EFO_0000712, EFO_0001645

Protein segments in the cluster

Peptide	Gene	Start	Entry
AGRVPAEGAPTAAVA	CTDP1	6	Q9Y5B0
GRSGAPAEREAEPRV	FBRSL1	811	Q9HCM7
TNITADIGTDPRGPR	B4GALT3	336	O60512
PTDAEGSPGLSRVRT	ARHGEF40	256	Q8TER5
RIGTAPAEPGLVEAA	C6orf226	76	Q5I0X4
EGPRSRPAAESTGLE	PRKAG3	76	Q9UGI9
VRAVDGEGAPAPESS	AKAP8	586	O43823
PERGTRTGAAATPEE	ALLC	106	Q8N6M5
SVPGLRPAEAGEFTR	GTPBP3	131	Q969Y2
AAGTALPAARPEDGR	BTBD17	376	A6NE02
PRLVVTPASSGGDAA	BTBD17	391	A6NE02
VGATGRDAVSPREPV	GUSBP11	31	Q6P575
GSTLDVGPARFRAPE	ACTR1B	246	P42025
EEGDRSGARSRAPPT	ANKS1A	596	Q92625
PGPLDVAAVAAGVRA	ASMT	41	P46597
TVEASDQGRDPGPRS	CELSR2	366	Q9HCU4
DQGRDPGPRSTTAAV	CELSR2	371	Q9HCU4
PAPGRATEGRAALDI	ADAMTS7	31	Q9UKP4
GAVATRDGEAPERSP	RAB37	6	Q96AX2
PGRRGPAALVSEVFE	NPAS1	121	Q99742
GPVRTAGLVATEPAR	CAPN15	106	O75808
LPTDSASRGGVAVVP	BCAN	631	Q96GW7
PRAAPGGADDLSAVR	FHIP1B	56	Q8N612
RAGSGVPPAFAVARV	DCHS1	866	Q96JQ0
EVIARGPLPGSRSAT	DCHS1	2901	Q96JQ0
SDPVRTGSEGLALPR	GLI3	1006	P10071
VRIRPPAERSGSADG	KIF15	31	Q9NS87
AGEASGAPPARILEA	KIAA1671	36	Q9BY89
VVTSGSPVAADRVGP	FLCN	466	Q8NFG4
SEGRIRAEVPGSPAV	CRB2	701	Q5IJ48
NGTLEPGTERRAPET	LMTK3	1081	Q96Q04
LSVTDGGSPVPARRA	BRSK2	386	Q8IWQ3
EVPRAGDRGSVSQSP	BSN	3196	Q9UPA5
SRAGNPEAAVAEGVP	ISLR	391	O14498
EGAGRPPAARATRAE	FBXW8	61	Q8N3Y1
ETVAAARPVTRSPGG	PDGFB	181	P01127
GEPPRARGAVLTATV	ICAM5	171	Q9UMF0
SERAGTPRVSGETPA	MUC19	1751	Q7Z5P9
APESRTAGVPSGTRV	MUC19	7131	Q7Z5P9
EEQRAGAEPGTRPSL	MYLK3	416	Q32MK0
RGETAVPGAPEALRA	PGP	41	A6NDG6
ERARTPEGDGISRPT	PDE4B	61	Q07343
TRPQEVEAEPRSGSG	NAT16	31	Q8N8M0
LPGPEVSGRSVAAAS	NDUFAF6	36	Q330K2
PRVGTPLATEDSGRS	KDM4B	1061	O94953
TSEGTPGFRAPEVAR	LRRK2	2031	Q5S007
AVAAGRSPEGVRDDP	KCNS1	256	Q96KK3
LTAPSEAEPGRGATV	MROH6	61	A6NGR9
SSTAAPDGVEGPALR	PDF	31	Q9HBH1
GAARATSPPGSAEIV	OC90	236	Q02509
RPGAAGASPTVRATV	RGL3	281	Q3MIN7
SVEPAQGEAREGSPR	GOLGA2	941	Q08379
ETSGREAPEAPAVGR	IQSEC3	531	Q9UPP2
RVDGDSPESRLTVPG	ITGB4	1691	P16144
EGGSAEERRLEPPSS	C17orf75	21	Q9HAS0
GPTDGSRETPAARDV	ITFG2	226	Q969R8
AATAGTPGPRREEEA	MEI1	6	Q5TIA1
DSRAGAQRDEPEPGT	GRIN3A	71	Q8TCU5
DTSAVLAEIPAGPGR	NRBP1	361	Q9UHY1
AGRAAPVSGSVTIPV	FAM171A2	606	A8MVW0
AEEEASAGPRGARPA	PAX1	491	P15863
QAEPGDTREPGVTTR	BECN2	36	A8MW95
ETPTPTQRGEAESRG	CD2BP2	261	O95400
RTSSEPPAGLRVSGE	BORCS6	31	Q96GS4
APARGEQRTAEPEGR	DACT1	16	Q9NYF0
LGDASPSAPEVVGAR	DACT3	166	Q96B18
PEETETPATRGRALG	CACNA1S	1691	Q13698
GGTPREVVVEGPAAS	COL20A1	416	Q9P218
RAREVGDPDSGVTPN	FAM83C	516	Q9BQN1
AGVGGERSSRPAPSV	GDF11	41	O95390
RDPGRPFESSGEVSA	DNAAF8	121	Q8IYS4
RSSSPAGETEGDREP	DIDO1	1711	Q9BTC0
PGSRRPLDEAVAGAE	DENND6A	11	Q8IWF6
PSEPAVVAAARVGVG	MPG	251	P29372
SVSLPSDPDRGVGRT	ADCY3	21	O60266
GPREEATAARGNSIP	MAN1C1	116	Q9NR34
DSGEGPRRLPEAAAA	MARCHF11	101	A6NNE9
RAELGAGAPPAVVAR	MAP7D1	6	Q3KQU3
RGARGSLPTTDAEPD	INSRR	1266	P14616
GEPESAGPSRAVRQS	EMD	106	P50402
SDEDLRGPGVRPSRT	DNAJC30	116	Q96LL9
LGVSPSESPAAERGA	CACNA1H	46	O95180
DGTPVRDERSGTPTQ	RPRD2	721	Q5VT52
TVVARLGPDAARGPA	SAC3D1	181	A6NKF1
VSEPAGAAAEGTLRP	SCT	106	P09683
AIGSVPERSPAGVDL	CEP131	6	Q9UPN4
DRDSGVVGARPRASP	OTUD5	51	Q96G74
GDQRRVPEVTGDAPS	POM121L1P	56	Q3SYA9
FGTEEAAPTRARGPE	PKD1	1416	P98161
AVNSIGRGPPSEAVR	PTPRF	391	P10586
GRGPPSEAVRARTGE	PTPRF	396	P10586
PEAAARAEAREAPGG	INSM1	331	Q01101
AAERTEGPAVGPLIS	GARIN3	386	Q8TC56
APVGAVAEARPGATA	RUNDC1	41	Q96C34
EAASGRGLRPVAPAT	SAP25	46	Q8TEE9
TESVRTPGGAERAPG	SZT2	2481	Q5T011
GAAPVAVEPGAAVRS	MRPL36	36	Q9P0J6
GSSRPDRSPAIEGIL	RNF115	131	Q9Y4L5
TGPLAARAGEPAERR	TAF10	61	Q12962
RGAERRPESFTTPEG	SLBP	51	Q14493
PSGVTALTPRRDGLE	SEMA4F	601	O95754
PGAVADASVPRTRGE	SNAP47	151	Q5SQN1
RTRVSLGGEPPSEAQ	SPATA5L1	181	Q9BVQ7
LVRAISEAGAPPGSA	TMEM121B	366	Q9BXQ6
TRDPFAPSRVAGVLG	SCYL1	476	Q96KG9
SVAAGVDAAEGPRAP	MMP17	531	Q9ULZ9
GFVARTECPTDGPAR	PKDREJ	176	Q9NTG1
AAVLRAAGAGPVRSP	GDF7	26	Q7Z4P5
DEARASPTRGPRGVA	PLCL2	66	Q9UPR0
RATDGAPADAPVGVL	SHROOM2	1076	Q13796
TRGTQRGDETPREPS	SHROOM3	1196	Q8TF72
REVAEGGLPRAESPS	SPINDOC	296	Q9BUA3
PGAERDAGAQADRTP	PPP1R26	1011	Q5T8A7
REEEAAVPAPGTTGI	PKHD1	3961	P08F94
PRARPEAAGSEGAAE	SKI	711	P12755
EGQARTLGPAAPTVD	B4GALNT4	601	Q76KP1
PERGAERRDTAPSGV	COA8	41	Q96IL0
EETTPRPGRAVASVG	CLEC20A	301	Q6ZU45
GESGPAVDGIRRTPA	C10orf55	136	Q5SWW7
OT REPRESENTABL	TTN	41	Q8WZ42
GTGPPALERVDAQSR	PLEKHG5	176	O94827
AVEDSPALGAPRVGA	RAPGEF3	16	O95398
SDPLRGEPGSARAAV	STK19	136	P49842
VGSLPAGERVSRPEA	USP19	956	O94966
AGERVSRPEAAVPGY	USP19	961	O94966
ERAVSDRLAPGAPRG	MYCL	106	P12524
EPARDGVEASAEGPR	TFE3	6	P19532
ARVAPGTATAAAGPV	REPS2	61	Q8NFH8
RGTEGFERPPASVSR	SPEM2	316	Q0P670
APRTEPSGRRGSDEL	SRCIN1	976	Q9C0H9
SRDRDPVFEITGAPG	MEX3A	261	A1L020
GSVGAREPEAAEPAT	SPIRE2	71	Q8WWL2
APREVVDPSGGRATL	WASH2P	351	Q6VEQ5
EAEAPRAPGLLGSRA	ZSCAN1	191	Q8NBB4
REPGSPAESEGRDQA	SPPL2B	566	Q8TCT7
DVRPPRAVAGFRGTV	TTBK2	176	Q6IQ55
APRPDGGRTLVFSER	NEURL1B	301	A8MQ27
SETPRGPGESVERAR	ZNF646	1646	O15015
AEAEGRPLREPGSSR	RGS14	186	O43566
PRVPDSTRRTDVGAG	TP53BP1	1441	Q12888
VRGQRPGSPEEAAAL	ZNF446	86	Q9NWS9
PASRAEGPVAVVVNG	ZNF598	621	Q86UK7
QVEGRRGPVSPSDSS	TOPAZ1	81	Q8N9V7
APVGASEIAEETRPG	ZNF853	71	P0CG23
ESENRPRAALGPVVG	ZNF213	281	O14771
TSPGDRVETPVGERA	PLEKHO2	216	Q8TD55
RAAAEELPVGASAGP	TXLNB	656	Q8N3L3
SRPSAPETDDSRVGG	TOGARAM1	26	Q9Y4F4
LRAAFEPRPGEDSAG	TIGD5	481	Q53EQ6
SDRAGGPRAFSEVPD	TMEM119	141	Q4V9L6
EPSALPVQGRAEGRS	nan	16	Q96M66
PVDTGVAARTPAVEG	TPD52L2	26	O43399
ATARRGSPGQEEELP	ZMYM3	166	Q14202
SRRPPGADAEGSERE	TRIO	2391	O75962
RLRDLGADPGVATTP	ZIC5	76	Q96T25
NRGIPATPRDGSAVE	AGL	1271	P35573
RPLETGPRDGVAVAA	NACC2	191	Q96BF6
FVRDADPLVTGAPGA	MYOM2	371	P54296