Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	6.73e-05	10	25	2	GO:0140031
GeneOntologyMolecularFunction	store-operated calcium channel activity	TRPC7 TRPC3	9.86e-05	12	25	2	GO:0015279
GeneOntologyMolecularFunction	inositol 1,4,5 trisphosphate binding	TRPC7 TRPC3	1.36e-04	14	25	2	GO:0070679
GeneOntologyMolecularFunction	kinase binding	CEP152 STX1A ANK2 WNK1 CADPS SDC4 STX1B	1.38e-04	969	25	7	GO:0019900
GeneOntologyMolecularFunction	cytoskeletal anchor activity	ANK2 ANK3	4.08e-04	24	25	2	GO:0008093
GeneOntologyMolecularFunction	protein kinase binding	CEP152 ANK2 WNK1 CADPS SDC4 STX1B	5.95e-04	873	25	6	GO:0019901
GeneOntologyMolecularFunction	spectrin binding	ANK2 ANK3	8.24e-04	34	25	2	GO:0030507
GeneOntologyMolecularFunction	ion channel regulator activity	STX1A ANK2 WNK1	1.06e-03	162	25	3	GO:0099106
GeneOntologyMolecularFunction	SNAP receptor activity	STX1A STX1B	1.08e-03	39	25	2	GO:0005484
GeneOntologyMolecularFunction	transmembrane transporter binding	STX1A ANK2 ANK3	1.26e-03	172	25	3	GO:0044325
GeneOntologyMolecularFunction	channel regulator activity	STX1A ANK2 WNK1	1.30e-03	174	25	3	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	STX1A ANK2 WNK1	1.36e-03	177	25	3	GO:0141108
GeneOntologyMolecularFunction	ion channel inhibitor activity	STX1A WNK1	1.64e-03	48	25	2	GO:0008200
GeneOntologyMolecularFunction	channel inhibitor activity	STX1A WNK1	1.78e-03	50	25	2	GO:0016248
GeneOntologyMolecularFunction	transporter inhibitor activity	STX1A WNK1	1.85e-03	51	25	2	GO:0141110
GeneOntologyMolecularFunction	potassium channel regulator activity	ANK2 WNK1	2.30e-03	57	25	2	GO:0015459
GeneOntologyMolecularFunction	molecular adaptor activity	STX1A ANK2 ANK3 WNK1 STX1B ITSN1	5.61e-03	1356	25	6	GO:0060090
GeneOntologyMolecularFunction	kinase regulator activity	WNK1 CCNB3 ITSN1	6.33e-03	305	25	3	GO:0019207
GeneOntologyMolecularFunction	alcohol binding	TRPC7 TRPC3	7.18e-03	102	25	2	GO:0043178
GeneOntologyBiologicalProcess	positive regulation of transport	CCR2 STX1A ANK2 ANK3 WNK1 CADPS SDC4 STX1B ITSN1 TRPC3	3.69e-07	1081	26	10	GO:0051050
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	CCR2 ANK2 ANK3 WNK1 TRPC3	3.72e-06	192	26	5	GO:0034767
GeneOntologyBiologicalProcess	synaptic vesicle priming	STX1A CADPS STX1B	7.81e-06	31	26	3	GO:0016082
GeneOntologyBiologicalProcess	regulation of termination of RNA polymerase II transcription	WNK1 SCAF4	9.15e-06	4	26	2	GO:1904594
GeneOntologyBiologicalProcess	regulation of exocytosis	CCR2 STX1A CADPS SDC4 STX1B	9.55e-06	233	26	5	GO:0017157
GeneOntologyBiologicalProcess	exocytosis	CCR2 STX1A CADPS SDC4 STX1B ITSN1	1.35e-05	434	26	6	GO:0006887
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	CCR2 STX1A ANK3 CADPS SDC4 STX1B ITSN1	1.38e-05	667	26	7	GO:0060627
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	CCR2 ANK2 ANK3 WNK1 TRPC3	1.81e-05	266	26	5	GO:0043270
GeneOntologyBiologicalProcess	positive regulation of transmembrane transport	CCR2 ANK2 ANK3 WNK1 TRPC3	2.05e-05	273	26	5	GO:0034764
GeneOntologyBiologicalProcess	regulation of termination of DNA-templated transcription	WNK1 SCAF4	2.28e-05	6	26	2	GO:0031554
GeneOntologyBiologicalProcess	regulation of secretion	CCR2 STX1A WNK1 CADPS SDC4 STX1B ITSN1	4.47e-05	801	26	7	GO:0051046
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	ANK2 ANK3 WNK1 TRPC3	6.33e-05	174	26	4	GO:1904064
GeneOntologyBiologicalProcess	inorganic ion homeostasis	CCR2 TRPC7 ANK2 ANK3 WNK1 TRPC3	1.01e-04	622	26	6	GO:0098771
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	STX1A CADPS SDC4 STX1B ITSN1	1.32e-04	404	26	5	GO:1903532
GeneOntologyBiologicalProcess	regulation of synaptic vesicle priming	STX1A STX1B	1.38e-04	14	26	2	GO:0010807
GeneOntologyBiologicalProcess	calcium-ion regulated exocytosis	STX1A CADPS STX1B	1.47e-04	82	26	3	GO:0017156
GeneOntologyBiologicalProcess	regulation of monoatomic ion transmembrane transport	CCR2 ANK2 ANK3 WNK1 TRPC3	1.53e-04	417	26	5	GO:0034765
GeneOntologyBiologicalProcess	positive regulation of T cell chemotaxis	CCR2 WNK1	1.81e-04	16	26	2	GO:0010820
GeneOntologyBiologicalProcess	termination of RNA polymerase II transcription	WNK1 SCAF4	1.81e-04	16	26	2	GO:0006369
GeneOntologyBiologicalProcess	positive regulation of secretion	STX1A CADPS SDC4 STX1B ITSN1	1.86e-04	435	26	5	GO:0051047
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	CCR2 TRPC7 ANK2 ANK3 WNK1 TRPC3	2.00e-04	705	26	6	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	CCR2 TRPC7 ANK2 ANK3 WNK1 TRPC3	2.19e-04	717	26	6	GO:0050801
GeneOntologyBiologicalProcess	positive regulation of ion transmembrane transporter activity	CCR2 ANK2 ANK3	2.42e-04	97	26	3	GO:0032414
GeneOntologyBiologicalProcess	regulation of potassium ion transmembrane transport	ANK2 ANK3 WNK1	2.42e-04	97	26	3	GO:1901379
GeneOntologyBiologicalProcess	regulation of secretion by cell	CCR2 STX1A CADPS SDC4 STX1B ITSN1	2.60e-04	740	26	6	GO:1903530
GeneOntologyBiologicalProcess	import into cell	CCR2 STX1A ANK2 ANK3 WNK1 STX1B ITSN1	2.80e-04	1074	26	7	GO:0098657
GeneOntologyBiologicalProcess	regulation of T cell chemotaxis	CCR2 WNK1	2.86e-04	20	26	2	GO:0010819
GeneOntologyBiologicalProcess	positive regulation of calcium ion-dependent exocytosis	STX1A CADPS	2.86e-04	20	26	2	GO:0045956
GeneOntologyBiologicalProcess	synaptic vesicle cycle	STX1A CADPS STX1B ITSN1	3.14e-04	264	26	4	GO:0099504
GeneOntologyBiologicalProcess	positive regulation of transporter activity	CCR2 ANK2 ANK3	3.24e-04	107	26	3	GO:0032411
GeneOntologyBiologicalProcess	exocytic process	STX1A CADPS STX1B	3.24e-04	107	26	3	GO:0140029
GeneOntologyBiologicalProcess	positive regulation of exocytosis	STX1A CADPS SDC4	3.24e-04	107	26	3	GO:0045921
GeneOntologyBiologicalProcess	positive regulation of lymphocyte chemotaxis	CCR2 WNK1	3.48e-04	22	26	2	GO:0140131
GeneOntologyBiologicalProcess	synaptic vesicle recycling	STX1A STX1B ITSN1	3.60e-04	111	26	3	GO:0036465
GeneOntologyBiologicalProcess	membrane depolarization during cardiac muscle cell action potential	ANK2 ANK3	3.80e-04	23	26	2	GO:0086012
GeneOntologyBiologicalProcess	positive regulation of neurotransmitter secretion	STX1A STX1B	4.50e-04	25	26	2	GO:0001956
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	CADPS STX1B	4.50e-04	25	26	2	GO:0048791
GeneOntologyBiologicalProcess	regulated exocytosis	CCR2 STX1A CADPS STX1B	4.54e-04	291	26	4	GO:0045055
GeneOntologyBiologicalProcess	regulation of potassium ion transport	ANK2 ANK3 WNK1	4.64e-04	121	26	3	GO:0043266
GeneOntologyBiologicalProcess	endocytosis	CCR2 STX1A ANK2 ANK3 STX1B ITSN1	4.72e-04	827	26	6	GO:0006897
GeneOntologyBiologicalProcess	synaptic vesicle exocytosis	STX1A CADPS STX1B	5.10e-04	125	26	3	GO:0016079
GeneOntologyBiologicalProcess	secretion	CCR2 STX1A WNK1 CADPS SDC4 STX1B ITSN1	6.08e-04	1221	26	7	GO:0046903
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	STX1A CADPS STX1B ITSN1	6.57e-04	321	26	4	GO:0099003
GeneOntologyBiologicalProcess	regulation of monoatomic ion transport	CCR2 ANK2 ANK3 WNK1 TRPC3	6.80e-04	577	26	5	GO:0043269
GeneOntologyBiologicalProcess	synaptic vesicle fusion to presynaptic active zone membrane	STX1A STX1B	6.95e-04	31	26	2	GO:0031629
GeneOntologyBiologicalProcess	regulation of lymphocyte chemotaxis	CCR2 WNK1	6.95e-04	31	26	2	GO:1901623
GeneOntologyBiologicalProcess	chemical homeostasis	CCR2 OR4M2 TRPC7 ANK2 ANK3 WNK1 TRPC3	6.97e-04	1249	26	7	GO:0048878
GeneOntologyBiologicalProcess	vesicle fusion to plasma membrane	STX1A STX1B	7.40e-04	32	26	2	GO:0099500
GeneOntologyBiologicalProcess	positive regulation of neurotransmitter transport	STX1A STX1B	7.40e-04	32	26	2	GO:0051590
GeneOntologyBiologicalProcess	regulation of transmembrane transport	CCR2 ANK2 ANK3 WNK1 TRPC3	7.47e-04	589	26	5	GO:0034762
GeneOntologyBiologicalProcess	T cell chemotaxis	CCR2 WNK1	7.88e-04	33	26	2	GO:0010818
GeneOntologyBiologicalProcess	DNA-templated transcription termination	WNK1 SCAF4	8.36e-04	34	26	2	GO:0006353
GeneOntologyBiologicalProcess	synaptic vesicle membrane organization	STX1A STX1B	9.38e-04	36	26	2	GO:0048499
GeneOntologyBiologicalProcess	membrane depolarization during action potential	ANK2 ANK3	9.38e-04	36	26	2	GO:0086010
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	CCR2 TRPC7 ANK2 WNK1 TRPC3	9.54e-04	622	26	5	GO:0006873
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	CCR2 TRPC7 ANK2 TRPC3	9.97e-04	359	26	4	GO:0006874
GeneOntologyBiologicalProcess	regulation of regulated secretory pathway	CCR2 STX1A CADPS	1.14e-03	165	26	3	GO:1903305
GeneOntologyBiologicalProcess	positive regulation of T cell migration	CCR2 WNK1	1.22e-03	41	26	2	GO:2000406
GeneOntologyBiologicalProcess	monoatomic ion transport	CCR2 TRPC7 ANK2 ANK3 WNK1 SLC10A5 TRPC3	1.23e-03	1374	26	7	GO:0006811
GeneOntologyBiologicalProcess	regulation of monoatomic cation transmembrane transport	ANK2 ANK3 WNK1 TRPC3	1.23e-03	380	26	4	GO:1904062
GeneOntologyBiologicalProcess	positive regulation of potassium ion transmembrane transport	ANK2 WNK1	1.28e-03	42	26	2	GO:1901381
GeneOntologyBiologicalProcess	metal ion transport	TRPC7 ANK2 ANK3 WNK1 SLC10A5 TRPC3	1.28e-03	1000	26	6	GO:0030001
GeneOntologyBiologicalProcess	positive regulation of excitatory postsynaptic potential	STX1A STX1B	1.34e-03	43	26	2	GO:2000463
GeneOntologyBiologicalProcess	calcium ion homeostasis	CCR2 TRPC7 ANK2 TRPC3	1.34e-03	389	26	4	GO:0055074
GeneOntologyBiologicalProcess	endomembrane system organization	STX1A ANK2 ANK3 WNK1 STX1B	1.35e-03	672	26	5	GO:0010256
GeneOntologyBiologicalProcess	regulation of calcium ion-dependent exocytosis	STX1A CADPS	1.46e-03	45	26	2	GO:0017158
GeneOntologyBiologicalProcess	protein localization to membrane	STX1A ANK2 ANK3 WNK1 STX1B	1.67e-03	705	26	5	GO:0072657
GeneOntologyBiologicalProcess	vesicle organization	STX1A CADPS SDC4 STX1B	1.70e-03	415	26	4	GO:0016050
GeneOntologyBiologicalProcess	regulation of cilium movement	OR4M2 DNAH11	1.73e-03	49	26	2	GO:0003352
GeneOntologyBiologicalProcess	positive regulation of lymphocyte migration	CCR2 WNK1	1.73e-03	49	26	2	GO:2000403
GeneOntologyBiologicalProcess	secretion by cell	CCR2 STX1A CADPS SDC4 STX1B ITSN1	1.76e-03	1064	26	6	GO:0032940
GeneOntologyBiologicalProcess	protein localization to cell periphery	ANK2 ANK3 WNK1 STX1B	1.81e-03	422	26	4	GO:1990778
GeneOntologyBiologicalProcess	signal release from synapse	STX1A CADPS STX1B	1.84e-03	195	26	3	GO:0099643
GeneOntologyBiologicalProcess	neurotransmitter secretion	STX1A CADPS STX1B	1.84e-03	195	26	3	GO:0007269
GeneOntologyBiologicalProcess	regulation of system process	STX1A ANK2 WNK1 STX1B TRPC3	1.99e-03	734	26	5	GO:0044057
GeneOntologyBiologicalProcess	lymphocyte chemotaxis	CCR2 WNK1	2.02e-03	53	26	2	GO:0048247
GeneOntologyBiologicalProcess	positive regulation of potassium ion transport	ANK2 WNK1	2.10e-03	54	26	2	GO:0043268
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CCR2 TRPC7 ANK2 ANK3 WNK1 TRPC3	2.23e-03	1115	26	6	GO:0034220
GeneOntologyBiologicalProcess	positive regulation of cation channel activity	ANK2 ANK3	2.26e-03	56	26	2	GO:2001259
GeneOntologyBiologicalProcess	regulation of T cell migration	CCR2 WNK1	2.26e-03	56	26	2	GO:2000404
GeneOntologyCellularComponent	costamere	ANK2 ANK3 SDC4	2.91e-06	22	27	3	GO:0043034
MousePheno	abnormal synaptic vesicle recycling	STX1A STX1B ITSN1	3.28e-06	21	20	3	MP:0004770
Domain	STX1A/1B	STX1A STX1B	1.58e-06	2	24	2	IPR028669
Domain	TRP_dom	TRPC7 TRPC3	2.37e-05	6	24	2	IPR013555
Domain	TRP_2	TRPC7 TRPC3	2.37e-05	6	24	2	PF08344
Domain	TRPC_channel	TRPC7 TRPC3	3.31e-05	7	24	2	IPR002153
Domain	ZU5	ANK2 ANK3	5.67e-05	9	24	2	SM00218
Domain	SynN	STX1A STX1B	5.67e-05	9	24	2	SM00503
Domain	ZU5	ANK2 ANK3	7.08e-05	10	24	2	PS51145
Domain	TRP_channel	TRPC7 TRPC3	8.64e-05	11	24	2	IPR004729
Domain	Syntaxin	STX1A STX1B	8.64e-05	11	24	2	PF00804
Domain	ZU5_dom	ANK2 ANK3	1.04e-04	12	24	2	IPR000906
Domain	ZU5	ANK2 ANK3	1.04e-04	12	24	2	PF00791
Domain	Syntaxin_N	STX1A STX1B	1.04e-04	12	24	2	IPR006011
Domain	Ank_2	TRPC7 ANK2 ANK3 TRPC3	1.51e-04	215	24	4	PF12796
Domain	SYNTAXIN	STX1A STX1B	1.88e-04	16	24	2	PS00914
Domain	Syntaxin/epimorphin_CS	STX1A STX1B	1.88e-04	16	24	2	IPR006012
Domain	Ank	TRPC7 ANK2 ANK3 TRPC3	1.90e-04	228	24	4	PF00023
Domain	-	TRPC7 ANK2 ANK3 TRPC3	2.62e-04	248	24	4	1.25.40.20
Domain	ANK	TRPC7 ANK2 ANK3 TRPC3	2.74e-04	251	24	4	SM00248
Domain	ANK_REPEAT	TRPC7 ANK2 ANK3 TRPC3	2.82e-04	253	24	4	PS50088
Domain	Ankyrin_rpt-contain_dom	TRPC7 ANK2 ANK3 TRPC3	2.87e-04	254	24	4	IPR020683
Domain	ANK_REP_REGION	TRPC7 ANK2 ANK3 TRPC3	2.87e-04	254	24	4	PS50297
Domain	Ankyrin_rpt	TRPC7 ANK2 ANK3 TRPC3	3.22e-04	262	24	4	IPR002110
Domain	SNARE	STX1A STX1B	3.27e-04	21	24	2	PF05739
Domain	t_SNARE	STX1A STX1B	3.60e-04	22	24	2	SM00397
Domain	T_SNARE	STX1A STX1B	5.05e-04	26	24	2	PS50192
Domain	DEATH	ANK2 ANK3	5.45e-04	27	24	2	SM00005
Domain	T_SNARE_dom	STX1A STX1B	6.29e-04	29	24	2	IPR000727
Domain	Death	ANK2 ANK3	8.15e-04	33	24	2	PF00531
Domain	Death_domain	ANK2 ANK3	1.08e-03	38	24	2	IPR000488
Domain	DEATH_DOMAIN	ANK2 ANK3	1.08e-03	38	24	2	PS50017
Domain	t-SNARE	STX1A STX1B	1.38e-03	43	24	2	IPR010989
Domain	-	ANK2 ANK3	6.30e-03	93	24	2	1.10.533.10
Domain	DEATH-like_dom	ANK2 ANK3	7.12e-03	99	24	2	IPR011029
Domain	Ion_trans_dom	TRPC7 TRPC3	9.34e-03	114	24	2	IPR005821
Domain	Ion_trans	TRPC7 TRPC3	9.34e-03	114	24	2	PF00520
Domain	C2	CADPS ITSN1	1.22e-02	131	24	2	PF00168
Domain	C2	CADPS ITSN1	1.33e-02	137	24	2	SM00239
Domain	C2	CADPS ITSN1	1.42e-02	142	24	2	PS50004
Pathway	WP_15Q11Q13_COPY_NUMBER_VARIATION	FANCD2 STX1A STX1B	8.78e-05	59	21	3	M48104
Pathway	REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING	TRPC7 TRPC3	9.44e-05	10	21	2	M27330
Pathway	REACTOME_NEUROTOXICITY_OF_CLOSTRIDIUM_TOXINS	STX1A STX1B	9.44e-05	10	21	2	M27018
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	PSMD1 TRPC7 ANK2 ANK3 ITSN1 TRPC3	1.44e-04	575	21	6	M29853
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	TRPC7 TRPC3	1.63e-04	13	21	2	MM14553
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	STX1A STX1B	1.90e-04	14	21	2	MM15277
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	STX1A STX1B	1.90e-04	14	21	2	M27564
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	TRPC7 TRPC3	2.50e-04	16	21	2	M26945
Pathway	WP_KCNQ2RELATED_EPILEPSIES	STX1A ANK3	3.56e-04	19	21	2	M48320
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPC7 WNK1 TRPC3	4.98e-04	106	21	3	M27200
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	TRPC7 TRPC3	6.21e-04	25	21	2	MM14511
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	PSMD1 STX1A TRPC7 ANK2 ANK3 STX1B ITSN1 TRPC3	6.73e-04	1432	21	8	M509
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	TRPC7 TRPC3	7.25e-04	27	21	2	M12123
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	TRPC7 TRPC3	7.25e-04	27	21	2	MM15053
Pathway	REACTOME_TRP_CHANNELS	TRPC7 TRPC3	7.81e-04	28	21	2	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPC7 TRPC3	7.81e-04	28	21	2	M27241
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	TRPC7 TRPC3	7.81e-04	28	21	2	M924
Pathway	REACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS	STX1A STX1B	8.38e-04	29	21	2	M27431
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	ANK2 ANK3	9.58e-04	31	21	2	M877
Pathway	KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT	STX1A STX1B	1.44e-03	38	21	2	M17857
Pathway	REACTOME_NETRIN_1_SIGNALING	TRPC7 TRPC3	1.93e-03	44	21	2	M875
Pubmed	Syntaxin 1B, but not syntaxin 1A, is necessary for the regulation of synaptic vesicle exocytosis and of the readily releasable pool at central synapses.	STX1A STX1B	5.80e-07	2	27	2	24587181
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	5.80e-07	2	27	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	5.80e-07	2	27	2	25383926
Pubmed	HPC-1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival.	STX1A STX1B	5.80e-07	2	27	2	24666284
Pubmed	Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.	STX1A STX1B	5.80e-07	2	27	2	24908488
Pubmed	Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain.	STX1A STX1B	5.80e-07	2	27	2	35638903
Pubmed	Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability.	STX1A STX1B	5.80e-07	2	27	2	24133272
Pubmed	A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse.	STX1A STX1B	5.80e-07	2	27	2	29912942
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	1.74e-06	3	27	2	33410423
Pubmed	Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells.	TRPC7 TRPC3	1.74e-06	3	27	2	15972814
Pubmed	Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent macropinocytosis and chemorepulsion.	STX1A STX1B	1.74e-06	3	27	2	37829513
Pubmed	Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules.	STX1A STX1B	1.74e-06	3	27	2	11112705
Pubmed	Syntaxin-1 and Insulinoma-Associated Protein 1 Expression in Breast Neoplasms with Neuroendocrine Features.	STX1A STX1B	1.74e-06	3	27	2	34764822
Pubmed	Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.	STX1A CADPS	1.74e-06	3	27	2	23801330
Pubmed	Reexamination of N-terminal domains of syntaxin-1 in vesicle fusion from central murine synapses.	STX1A STX1B	1.74e-06	3	27	2	34427183
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	1.74e-06	3	27	2	15611082
Pubmed	Syntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusion.	STX1A STX1B	1.74e-06	3	27	2	23188083
Pubmed	A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.	TRPC7 TRPC3	1.74e-06	3	27	2	19812035
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	1.74e-06	3	27	2	34289389
Pubmed	Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.	TRPC7 TRPC3	1.74e-06	3	27	2	28526717
Pubmed	Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells.	STX1A STX1B	3.48e-06	4	27	2	10468580
Pubmed	Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.	TRPC7 TRPC3	3.48e-06	4	27	2	30017393
Pubmed	Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ.	STX1A STX1B	3.48e-06	4	27	2	23821748
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	5.80e-06	5	27	2	25950943
Pubmed	Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain.	STX1A STX1B	5.80e-06	5	27	2	15659226
Pubmed	TRPC channels are necessary mediators of pathologic cardiac hypertrophy.	TRPC7 TRPC3	5.80e-06	5	27	2	20351294
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	5.80e-06	5	27	2	25362471
Pubmed	Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay.	STX1A STX1B	5.80e-06	5	27	2	12093152
Pubmed	Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.	TRPC7 TRPC3	5.80e-06	5	27	2	21261756
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	5.80e-06	5	27	2	19109891
Pubmed	Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction.	STX1A STX1B	8.69e-06	6	27	2	15774481
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	8.69e-06	6	27	2	23728480
Pubmed	MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.	TRPC7 TRPC3	1.22e-05	7	27	2	15757897
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	1.22e-05	7	27	2	7495297
Pubmed	TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.	TRPC7 TRPC3	1.22e-05	7	27	2	38835669
Pubmed	MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development.	STX1A STX1B	1.22e-05	7	27	2	29191246
Pubmed	EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?	STX1A ITSN1	1.22e-05	7	27	2	10373452
Pubmed	Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin.	STX1A STX1B	1.22e-05	7	27	2	8999968
Pubmed	RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.	TRPC7 TRPC3	1.22e-05	7	27	2	32350291
Pubmed	Conformational switch of syntaxin-1 controls synaptic vesicle fusion.	STX1A STX1B	1.22e-05	7	27	2	18703708
Pubmed	TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.	TRPC7 TRPC3	1.22e-05	7	27	2	36592529
Pubmed	Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.	TRPC7 TRPC3	1.22e-05	7	27	2	15336983
Pubmed	Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.	TRPC7 TRPC3	1.22e-05	7	27	2	36257322
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	PSMD1 CEP152 ANK2	1.39e-05	60	27	3	20682791
Pubmed	Subunit composition of mammalian transient receptor potential channels in living cells.	TRPC7 TRPC3	1.62e-05	8	27	2	12032305
Pubmed	Association of immunophilins with mammalian TRPC channels.	TRPC7 TRPC3	1.62e-05	8	27	2	15199065
Pubmed	Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.	STX1A STX1B	1.62e-05	8	27	2	24744148
Pubmed	A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones.	STX1A STX1B	1.62e-05	8	27	2	21994363
Pubmed	Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.	TRPC7 TRPC3	1.62e-05	8	27	2	25471572
Pubmed	Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.	STX1A STX1B	1.62e-05	8	27	2	22404429
Pubmed	Discovery of tissue-specific exons using comprehensive human exon microarrays.	ANK2 WNK1	2.08e-05	9	27	2	17456239
Pubmed	Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.	TRPC7 TRPC3	2.08e-05	9	27	2	11290752
Pubmed	Syntaxin isoform specificity in the regulation of renal H+-ATPase exocytosis.	STX1A STX1B	2.08e-05	9	27	2	12651853
Pubmed	Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.	ANK2 ANK3	2.08e-05	9	27	2	29867141
Pubmed	Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.	TRPC7 TRPC3	2.08e-05	9	27	2	17480026
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 ANK3	2.60e-05	10	27	2	22159418
Pubmed	Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons.	STX1A STX1B	2.60e-05	10	27	2	27466336
Pubmed	CAPS1 regulates catecholamine loading of large dense-core vesicles.	STX1A CADPS	2.60e-05	10	27	2	15820695
Pubmed	Heterogeneous distribution of TRPC proteins in the embryonic cortex.	TRPC7 TRPC3	2.60e-05	10	27	2	18989690
Pubmed	SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.	STX1A CADPS	2.60e-05	10	27	2	21040848
Pubmed	The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.	TRPC7 TRPC3	2.60e-05	10	27	2	27177420
Pubmed	The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.	STX1A CADPS	3.18e-05	11	27	2	25374362
Pubmed	LTP requires a unique postsynaptic SNARE fusion machinery.	STX1A STX1B	3.81e-05	12	27	2	23395379
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MKRN3 PSMD1 STX1A ANK2 ANK3 CADPS ITSN1	4.29e-05	1285	27	7	35914814
Pubmed	Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1).	STX1A STX1B	4.50e-05	13	27	2	30870432
Pubmed	Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.	STX1A STX1B	4.50e-05	13	27	2	15145078
Pubmed	Melanopsin signalling in mammalian iris and retina.	TRPC7 TRPC3	4.50e-05	13	27	2	22051675
Pubmed	Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon.	STX1A STX1B	5.25e-05	14	27	2	19892785
Pubmed	LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.	CADPS STX1B	6.06e-05	15	27	2	21307259
Pubmed	Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.	STX1A STX1B	6.06e-05	15	27	2	23064108
Pubmed	Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.	ANK2 ANK3	6.06e-05	15	27	2	30562487
Pubmed	Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance.	STX1A STX1B	6.06e-05	15	27	2	18507827
Pubmed	Determination of retinal cell fates is affected in the absence of extraocular striated muscles.	STX1A STX1B	6.06e-05	15	27	2	12619134
Pubmed	Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype.	STX1A STX1B	6.92e-05	16	27	2	18224708
Pubmed	The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.	STX1A STX1B	6.92e-05	16	27	2	20881139
Pubmed	Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106.	STX1A STX1B	7.84e-05	17	27	2	27418600
Pubmed	Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.	TRPC7 TRPC3	7.84e-05	17	27	2	22411552
Pubmed	The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth.	STX1A STX1B	8.81e-05	18	27	2	19546860
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 ANK3	8.81e-05	18	27	2	37321992
Pubmed	Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.	ANK2 ANK3	8.81e-05	18	27	2	31910261
Pubmed	BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.	STX1A STX1B	8.81e-05	18	27	2	12588844
Pubmed	Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.	TRPC7 TRPC3	1.21e-04	21	27	2	30270038
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	STX1A ANK3 CADPS	1.34e-04	128	27	3	30995482
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPC7 TRPC3	1.59e-04	24	27	2	33884443
Pubmed	Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.	STX1A STX1B	1.72e-04	25	27	2	15935055
Pubmed	VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.	STX1A STX1B	1.72e-04	25	27	2	24885147
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPC7 TRPC3	1.72e-04	25	27	2	16382100
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PSMD1 STX1A ANK2 ANK3 CADPS STX1B	2.00e-04	1139	27	6	36417873
Pubmed	An introduction to TRP channels.	TRPC7 TRPC3	2.01e-04	27	27	2	16460286
Pubmed	Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.	STX1A STX1B	2.01e-04	27	27	2	19723784
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPC7 TRPC3	3.02e-04	33	27	2	19834762
Pubmed	Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.	STX1A STX1B	3.21e-04	34	27	2	21138975
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	AFF2 ANK3 WNK1 ITSN1	3.23e-04	430	27	4	35044719
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	TRPC7 TRPC3	4.01e-04	38	27	2	30786075
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ANK2 ANK3 ITSN1	4.74e-04	197	27	3	36604605
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	ANK2 WNK1 CADPS	5.09e-04	202	27	3	33601422
Pubmed	A human MAP kinase interactome.	PSMD1 ANK3 WNK1 ITSN1	5.12e-04	486	27	4	20936779
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPC7 TRPC3	5.38e-04	44	27	2	19322198
Pubmed	The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.	TRPC7 TRPC3 SCAF4	5.86e-04	212	27	3	19521566
Pubmed	mTORC1 accelerates retinal development via the immunoproteasome.	PSMD1 STX1A	5.88e-04	46	27	2	29950673
Interaction	GPM6A interactions	STX1A ANK2 EDA CADPS STX1B	1.13e-06	168	23	5	int:GPM6A
Interaction	TRPC7 interactions	TRPC7 TRPC3	1.86e-05	6	23	2	int:TRPC7
Interaction	ZYX interactions	FANCD2 CEP152 ANK2 WNK1 ITSN1	2.97e-05	329	23	5	int:ZYX
Interaction	OTUD7A interactions	ANK2 ANK3 ITSN1	3.85e-05	58	23	3	int:OTUD7A
Interaction	RAPGEF5 interactions	ANK2 ANK3 WNK1	4.26e-05	60	23	3	int:RAPGEF5
Interaction	SNAP23 interactions	FANCD2 STX1A STX1B ITSN1	6.78e-05	197	23	4	int:SNAP23
Interaction	CHL1 interactions	ANK2 ANK3	8.17e-05	12	23	2	int:CHL1
Interaction	MAL interactions	STX1A EDA SDC4	1.08e-04	82	23	3	int:MAL
Cytoband	Ensembl 112 genes in cytogenetic band chr15q11	MKRN3 OR4M2 OR4M2B	2.80e-04	217	27	3	chr15q11
GeneFamily	Syntaxins	STX1A STX1B	1.68e-04	16	22	2	818
GeneFamily	Transient receptor potential cation channels	TRPC7 TRPC3	5.24e-04	28	22	2	249
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_CTL\|Int-URO / Disease, Lineage and Cell Type	GNLY CCNB3 EDA CADPS	1.81e-06	153	26	4	fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 WNK1 SDC4 DNAH11	3.46e-06	180	26	4	fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 WNK1 SDC4 DNAH11	3.46e-06	180	26	4	6763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AFF2 CADPS TRPC3 DNAH11	4.28e-06	190	26	4	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK2 ANK3 EDA CADPS	4.65e-06	194	26	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ANK2 ANK3 EDA CADPS	4.65e-06	194	26	4	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MKRN3 CCR2 DNAH11	1.70e-05	86	26	3	db67c05c876a5649371c0dc6c941cc371bc2feb8
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MKRN3 CCR2 DNAH11	1.70e-05	86	26	3	2778446e035c5585bce28ed0ef93b87b6ad90c6e
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MKRN3 B3GNT5 CCNB3	3.36e-05	108	26	3	63d45cc3ee149a7baf255b70409f8ea54c56157b
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P3-Tnr\|Thalamus / BrainAtlas - Mouse McCarroll V32	MKRN3 B3GNT5 CCNB3	3.36e-05	108	26	3	d57eeda825b6e0e64bae185896ae7eea6a2a50e9
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P3\|Thalamus / BrainAtlas - Mouse McCarroll V32	MKRN3 B3GNT5 CCNB3	3.36e-05	108	26	3	db8472616886c6195f8c27c00f00133a9c10691d
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	MKRN3 B3GNT5 CCNB3	3.36e-05	108	26	3	c2aa6bf8554bfb6b0f9c5f6658601c6cf7c8bdbc
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|390C / Donor, Lineage, Cell class and subclass (all cells)	GNLY STX1B TRPC3	6.11e-05	132	26	3	a1f98d9245c8fe02ea3f098f04919a7d5fc6cbc7
ToppCell	Severe-B_intermediate-14\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 SDC4	7.59e-05	142	26	3	f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCell	Severe-B_intermediate-14\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 SDC4	7.59e-05	142	26	3	9c7d5783302974b883bd887f997d094eb5925ec2
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	TRPC7 AFF2 DNAH11	8.75e-05	149	26	3	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	Influenza_Severe-CD4+_T_naive\|World / Disease group and Cell class	ANK3 EDA STX1B	8.75e-05	149	26	3	ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCR2 ANK3 SDC4	9.10e-05	151	26	3	fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	STX1A ANK3 B3GNT5	9.65e-05	154	26	3	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	CCR2 EDA CC2D2B	1.04e-04	158	26	3	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	B3GNT5 SDC4 STX1B	1.04e-04	158	26	3	0559cc032d0b518bb9e55aa3495f5573bd8e87dd
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-gdT\|ICU-NoSEP / Disease, Lineage and Cell Type	GNLY CADPS TRPC3	1.08e-04	160	26	3	2798c5bd971407f27dd4d3a4831d63d9c88003c3
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCD2 CCR2 CEP152	1.14e-04	163	26	3	7af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	CCR2 B3GNT5 CCNB3	1.16e-04	164	26	3	057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR2 STX1A ANK3	1.18e-04	165	26	3	354978d4f35154d7b2e36e94de669e045adef512
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	TRPC7 AFF2 B3GNT5	1.23e-04	167	26	3	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	TRPC7 AFF2 B3GNT5	1.23e-04	167	26	3	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FANCD2 TRPC7 B3GNT5	1.25e-04	168	26	3	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|Monocyte / Lineage, cell class and subclass	STX1A B3GNT5 SDC4	1.27e-04	169	26	3	7c3144a6599787f28662f5b22b8e45f4a115aeda
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MKRN3 ANK2 CADPS	1.32e-04	171	26	3	b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC7 AFF2 EDA	1.46e-04	177	26	3	64fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AFF2 CADPS DNAH11	1.46e-04	177	26	3	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STX1A ANK2 CADPS	1.51e-04	179	26	3	878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STX1A TRPC7 CADPS	1.51e-04	179	26	3	ec7c38464863ac3744a8d4880f49421914892339
ToppCell	3'_v3-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	AFF2 CADPS SLC10A5	1.53e-04	180	26	3	b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC7 AFF2 EDA	1.56e-04	181	26	3	b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	AFF2 CADPS SLC10A5	1.56e-04	181	26	3	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.61e-04	183	26	3	f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.63e-04	184	26	3	8939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	FANCD2 CEP152 AFF2	1.66e-04	185	26	3	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CEP152 TRPC7 TRPC3	1.66e-04	185	26	3	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC7 WNK1 SDC4	1.69e-04	186	26	3	7380af16e537cc49a2bb24ac50663d13c38459a7
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC7 WNK1 SDC4	1.69e-04	186	26	3	d56ccbe26bfddba0e2c54e7c7a5ca7f46fd3d891
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK2 ANK3 CADPS	1.74e-04	188	26	3	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.74e-04	188	26	3	d2d2b6c49448da24f457cedcd213f68841834a99
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	STX1A ANK2 CADPS	1.74e-04	188	26	3	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ANK3 SDC4 DNAH11	1.74e-04	188	26	3	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 SDC4 DNAH11	1.77e-04	189	26	3	4e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.77e-04	189	26	3	ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.77e-04	189	26	3	e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCell	droplet-Heart-HEART-1m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 SDC4 DNAH11	1.77e-04	189	26	3	a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	STX1A ANK2 CADPS	1.79e-04	190	26	3	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	STX1A ANK2 CADPS	1.79e-04	190	26	3	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ANK2 ANK3 CADPS	1.82e-04	191	26	3	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	367C-Epithelial_cells\|367C / Donor, Lineage, Cell class and subclass (all cells)	ANK3 SDC4 DNAH11	1.82e-04	191	26	3	d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AFF2 CADPS DNAH11	1.85e-04	192	26	3	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.85e-04	192	26	3	6fb56d062c35617b18b927704bf5fba894faed81
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.88e-04	193	26	3	b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.88e-04	193	26	3	241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 WNK1 SDC4	1.88e-04	193	26	3	fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	ANK2 ANK3 CADPS	1.94e-04	195	26	3	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	proximal-3-Hematologic-IGSF21+_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCR2 CEP152 EDA	1.94e-04	195	26	3	8592d0332bc82a91e173680cfd1afc5ee189b289
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 WNK1 SDC4	1.94e-04	195	26	3	3123e02d2894c83962ba402085b5e6422ebf8c73
ToppCell	proximal-Hematologic-IGSF21+_Dendritic\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCR2 CEP152 EDA	1.94e-04	195	26	3	c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCell	proximal-Hematologic-IGSF21+_Dendritic-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCR2 CEP152 EDA	1.94e-04	195	26	3	ae9d61011e95f7840cbb154738c79745fd29943e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	GNLY ANK3 SDC4	1.97e-04	196	26	3	939c0d835e9700ac61df60884d3d86053b296410
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CCR2 B3GNT5 EDA	2.00e-04	197	26	3	0a404b4494a2246d5a92299235056f0fda4d2b48
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	B3GNT5 EDA ITSN1	2.03e-04	198	26	3	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL\|Int-URO / Disease, condition lineage and cell class	GNLY CCNB3 EDA	2.03e-04	198	26	3	717735d755745439f97ba1b71785c73945dfa9c5
ToppCell	Sepsis-URO-Lymphocyte-T/NK-MAIT\|URO / Disease, condition lineage and cell class	MKRN3 GNLY STX1A	2.03e-04	198	26	3	75db638278d4be2b0f406cd8871058a8352c5a86
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	STX1A ANK2 ANK3	2.06e-04	199	26	3	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD3-NKT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MKRN3 CCR2 GNLY	2.06e-04	199	26	3	d3dc52e1f0040763888f951a7c047db4a329a653
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	STX1A ANK2 ANK3	2.06e-04	199	26	3	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD3\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MKRN3 CCR2 GNLY	2.06e-04	199	26	3	4be4527f351b701438a8bcb738229a06dbf8bc96
ToppCell	Tracheal-10x3prime_v2-Epithelial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 SDC4 DNAH11	2.09e-04	200	26	3	e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCell	Neuronal-Excitatory-eH(THEMIS)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	651ee624ab62720546cf71c2191996b5be3ce846
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	73b7e395398fdc9aa5adb3ade675ae0168d7f46c
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	c9113e7a9624499db3e66c01462159e8e8781cc4
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	67ba7e5703842e38fa3508ac644461489043626f
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	0248fe1eac23704687a2f11c6a3775bceae7a2b1
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	f545ae8486bd72159247e055f0bb2796c254af61
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	8acccefa60031541277fe6c1a7f58f7450961836
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	473e85930f433e392956a7a10ea5d09fdc2a35b1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	STX1A ANK2 ANK3	2.09e-04	200	26	3	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TRPC7 EDA CADPS	2.09e-04	200	26	3	a737c4f535723e389ba4b957ae1fdc5162d3d951
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|356C / Donor, Lineage, Cell class and subclass (all cells)	GNLY TRPC3	8.91e-04	76	26	2	a3730df3d80a9285b26907d82db28a86039f62b6
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e-Excitatory_Neuron.Sc17a7.Sema3e-Nnat_(Layer_6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FANCD2 B3GNT5	1.17e-03	87	26	2	7518ca56d626619d9706505169a85f1850105608
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EDA SLC10A5	1.72e-03	106	26	2	c890c838785dfeda30f3b563194da9cfb49b157a
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FANCD2 DNAH11	1.82e-03	109	26	2	e3696d84da1dcd15f15d0434ea9d1955f2af22d6
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FANCD2 DNAH11	1.82e-03	109	26	2	6678036ff66c825a18d2506e33be421c27cf82e1
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FANCD2 DNAH11	1.82e-03	109	26	2	87f647cfebbb7de725e434cc27058e1c6accbb90
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FANCD2 DNAH11	1.82e-03	109	26	2	c9d1e69f9841135f4d114563a293a69a8ba5f965
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 DNAH11	1.85e-03	110	26	2	ee45592e936d32881c0f3429c21360670e5b3ce3
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 DNAH11	1.85e-03	110	26	2	b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 TRPC3	2.02e-03	115	26	2	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	RA-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	EDA CADPS	2.02e-03	115	26	2	0a37816898eaa18ae49d4d936e1a760f089e0ceb
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 TRPC3	2.02e-03	115	26	2	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 TRPC3	2.02e-03	115	26	2	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 ANK3	2.06e-03	116	26	2	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Arhgap25\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRPC7 TRPC3	2.09e-03	117	26	2	e1a14b8413a6f4b194217a90eb2c5f95ab14522e
Computational	Genes in the cancer module 563.	STX1A CADPS	2.16e-04	15	16	2	MODULE_563
Drug	OX-3	STX1A AFF2 EDA	2.04e-06	23	25	3	CID016122594
Drug	AC1L9KAY	AFF2 EDA TRPC3	4.66e-06	30	25	3	CID000446966
Drug	botulinum toxin type C	STX1A STX1B	6.94e-06	4	25	2	ctd:C096324
Drug	G11459	STX1A AFF2 DNAH11	1.40e-05	43	25	3	CID000472328
Drug	3-doxylandrostanol	ANK2 ANK3	4.15e-05	9	25	2	CID000189075
Drug	AC1L4HUP	ANK2 ANK3 EDA	4.24e-05	62	25	3	CID000185960
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; MCF7; HT_HG-U133A	CEP152 ANK3 WNK1 SCAF4	5.29e-05	191	25	4	4981_DN
Drug	Epivincamine [6835-99-0]; Up 200; 11.2uM; HL60; HG-U133A	CEP152 STX1A ITSN1 SCAF4	5.62e-05	194	25	4	1783_UP
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HT_HG-U133A	WNK1 EDA ITSN1 TRPC3	5.96e-05	197	25	4	6683_UP
Drug	Benzbromarone [3562-84-3]; Down 200; 9.4uM; HL60; HT_HG-U133A	CEP152 WNK1 ITSN1 SCAF4	6.08e-05	198	25	4	1291_DN
Drug	Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A	AFF2 WNK1 ITSN1 SCAF4	6.08e-05	198	25	4	1507_UP
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; HL60; HT_HG-U133A	TRPC7 AFF2 ANK2 ANK3	6.08e-05	198	25	4	3059_UP
Drug	Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A	CEP152 AFF2 EDA TRPC3	6.20e-05	199	25	4	4188_UP
Drug	Naringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A	TRPC7 EDA TRPC3 SCAF4	6.32e-05	200	25	4	4605_UP
Drug	Furazolidone [67-45-8]; Up 200; 17.8uM; HL60; HT_HG-U133A	TRPC7 AFF2 ANK3 TRPC3	6.32e-05	200	25	4	3019_UP
Drug	AC1NSPXR	ANK2 ANK3	6.33e-05	11	25	2	CID005313815
Drug	26-nor-25-doxylcholestanol	ANK2 ANK3	6.33e-05	11	25	2	CID000125890
Drug	20,25-diazacholesterol	ANK2 ANK3	6.33e-05	11	25	2	CID000009402
Drug	1-oleoyl-2-acetylglycerol	TRPC7 TRPC3	1.20e-04	15	25	2	ctd:C038237
Disease	nicotine dependence (implicated_via_orthology)	TRPC7 TRPC3	4.52e-05	12	25	2	DOID:0050742 (implicated_via_orthology)
Disease	Vertigo	PSMD1 CADPS SLC10A5	2.18e-04	139	25	3	HP_0002321
Disease	Colorectal Carcinoma	MKRN3 ANK2 WNK1 CCNB3 EDA	2.69e-04	702	25	5	C0009402
Disease	susceptibility to bacterial meningitis measurement	ANK3 SDC4	8.90e-04	52	25	2	EFO_0008411
Disease	biological sex	ANK3 CADPS ITSN1	9.47e-04	230	25	3	PATO_0000047
Disease	Petit mal status	CCR2 ANK3	1.47e-03	67	25	2	C0270823
Disease	Status Epilepticus, Subclinical	CCR2 ANK3	1.47e-03	67	25	2	C0751522
Disease	Simple Partial Status Epilepticus	CCR2 ANK3	1.47e-03	67	25	2	C0751524
Disease	Non-Convulsive Status Epilepticus	CCR2 ANK3	1.47e-03	67	25	2	C0751523
Disease	Grand Mal Status Epilepticus	CCR2 ANK3	1.47e-03	67	25	2	C0311335
Disease	Complex Partial Status Epilepticus	CCR2 ANK3	1.47e-03	67	25	2	C0393734
Disease	Status Epilepticus	CCR2 ANK3	1.52e-03	68	25	2	C0038220
Disease	Manic Disorder	ANK3 TRPC3	1.65e-03	71	25	2	C0024713
Disease	intellectual disability (implicated_via_orthology)	ANK2 ITSN1	1.84e-03	75	25	2	DOID:1059 (implicated_via_orthology)
Disease	Manic	ANK3 TRPC3	1.99e-03	78	25	2	C0338831
Disease	Depression, Bipolar	ANK3 TRPC3	2.04e-03	79	25	2	C0005587

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKAVKKIKCDMLRYI	CEP152	1271	O94986
RCLSLLYLRMFKLKK	AFF2	1161	P51816
AVLREVKYLLMLKKQ	DNAH11	726	Q96DT5
RLIMKRIVKISKCNL	CC2D2B	796	Q6DHV5
VKLVDLYLMKAVCKK	CCNB3	1186	Q8WWL7
VKAAMRKLVTKYILC	OR4M2B	296	A0A0X1KG70
CKKNRIKVMELLVKY	ANK2	406	Q01484
LHIYQLKTLIRMVKK	CADPS	1281	Q9ULU8
VKAAMRKLVTKYILC	OR4M2	296	Q8NGB6
LFLIVMIFRCAKLVK	CTXND2	26	A0A1B0GV90
YRTCLTIVQKLKKMV	GNLY	66	P22749
QIYCRLMKIILLCKI	B3GNT5	351	Q9BYG0
VCLLKARQKIAVKMV	EDA	351	Q92838
KELIMCNIKLLKALR	ITSN1	1286	Q15811
IACKKNRIKVMELLL	ANK3	406	Q12955
MLVVLILINCKKLKC	CCR2	61	P41597
AVFLILLLMYRMKKK	SDC4	161	P31431
MILITKAAIKAIKLY	SCAF4	26	O95104
KKTLELLVCRVKAML	FANCD2	1361	Q9BXW9
KVLRVLVKIYMNLEK	PSMD1	196	Q99460
MLLIILVYKAKKRCI	SLC10A5	411	Q5PT55
MLYKSIKKELVVLRL	MKRN3	456	Q13064
ARRKKIMIIICCVIL	STX1A	261	Q16623
YQSKARRKKIMIIIC	STX1B	256	P61266
TYLKRFKVMKIKVLR	WNK1	311	Q9H4A3
IMKRLIKRYVLKAQV	TRPC3	766	Q13507
QKIMKRLIKRYVLKA	TRPC7	781	Q9HCX4