Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	immunoglobulin production	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-13 IGKV1D-12 IGKV1D-8	2.73e-12	241	58	12	GO:0002377
GeneOntologyBiologicalProcess	production of molecular mediator of immune response	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.04e-09	403	58	12	GO:0002440
GeneOntologyBiologicalProcess	adaptive immune response	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 ZC3H12A IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-13 IGKV1D-12 IGKV1D-8 TFE3	5.75e-08	838	58	14	GO:0002250
GeneOntologyBiologicalProcess	adherens junction assembly	ZNF703 DLG5 ABI2	7.51e-06	14	58	3	GO:0034333
GeneOntologyBiologicalProcess	zonula adherens assembly	DLG5 ABI2	7.77e-06	2	58	2	GO:0045186
GeneOntologyBiologicalProcess	positive regulation of miRNA metabolic process	ZC3H12A GATA2 SREBF1 AR	5.30e-05	73	58	4	GO:2000630
GeneOntologyBiologicalProcess	positive regulation of protein tyrosine kinase activity	CSF1R ABI2 DVL2	1.30e-04	35	58	3	GO:0061098
GeneOntologyBiologicalProcess	regulation of miRNA metabolic process	ZC3H12A GATA2 SREBF1 AR	2.02e-04	103	58	4	GO:2000628
GeneOntologyCellularComponent	immunoglobulin complex	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-13 IGKV1D-12 IGKV1D-8	3.41e-14	166	59	12	GO:0019814
MousePheno	neurodegeneration	NEFM CSF1R KLC2 CACNA1G IRS2 NPHP4 DCTN1 AR	3.00e-05	468	38	8	MP:0002229
Domain	PH_DOMAIN	PSD ADRM1 PLEKHG3 RALGPS1 PHLPP1 IRS2	5.26e-05	279	45	6	PS50003
Domain	PH	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	2.17e-04	229	45	5	PF00169
Domain	PH	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	5.29e-04	278	45	5	SM00233
Domain	PH_domain	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	5.47e-04	280	45	5	IPR001849
Domain	PP2C	PPM1M PHLPP1	9.46e-04	19	45	2	PF00481
Domain	PP2Cc	PPM1M PHLPP1	1.05e-03	20	45	2	SM00332
Domain	-	PPM1M PHLPP1	1.05e-03	20	45	2	3.60.40.10
Domain	PPM_2	PPM1M PHLPP1	1.05e-03	20	45	2	PS51746
Domain	PPM-type_phosphatase_dom	PPM1M PHLPP1	1.05e-03	20	45	2	IPR001932
Domain	-	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	2.41e-03	391	45	5	2.30.29.30
Domain	PH_dom-like	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	3.48e-03	426	45	5	IPR011993
Domain	Channel_four-helix_dom	KCNA3 CACNA1G	8.33e-03	57	45	2	IPR027359
Domain	-	KCNA3 CACNA1G	8.33e-03	57	45	2	1.20.120.350
Domain	-	GATA2 AR	8.33e-03	57	45	2	3.30.50.10
Domain	Znf_NHR/GATA	GATA2 AR	8.61e-03	58	45	2	IPR013088
Domain	ZF_C3H1	ZC3H12A ZFP36L2	8.61e-03	58	45	2	PS50103
Domain	Intermediate_filament_CS	NEFM KRT71	1.01e-02	63	45	2	IPR018039
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.60e-07	61	39	5	M27581
Pathway	REACTOME_PARASITE_INFECTION	IGKV1-39 IGKV1-12 ABI2 IGKV1D-39 IGKV1D-16 IGKV1D-12	7.13e-07	116	39	6	M29843
Pathway	REACTOME_FCGR_ACTIVATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.23e-06	69	39	5	M27108
Pathway	REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.23e-06	69	39	5	M27150
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.42e-06	71	39	5	M1078
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.42e-06	71	39	5	M27203
Pathway	REACTOME_LEISHMANIA_INFECTION	IGKV1-39 IGKV1-12 ABI2 DVL2 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.00e-06	219	39	7	M29836
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGKV1-39 IGKV1-12 ABI2 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.43e-06	143	39	6	M27107
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.57e-06	80	39	5	M6121
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.90e-06	82	39	5	M27110
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.67e-06	86	39	5	M27206
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.67e-06	86	39	5	M601
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.89e-06	87	39	5	M27205
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.00e-06	95	39	5	M29842
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.99e-06	98	39	5	M27152
Pathway	REACTOME_COMPLEMENT_CASCADE	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.53e-05	115	39	5	M19752
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.20e-05	134	39	5	M29840
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.43e-05	136	39	5	M27207
Pathway	REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.22e-05	154	39	5	M39007
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	8.88e-05	166	39	5	M608
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	IGKV1-39 IGKV1-12 VPS37A DVL2 KLC2 IGKV1D-39 IGKV1D-16 IGKV1D-12 DCTN1	1.26e-04	725	39	9	M27507
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.52e-04	186	39	5	M27175
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.67e-04	190	39	5	M8240
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.85e-04	194	39	5	M16312
Pathway	WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS	GATA2 SREBF1	5.71e-04	13	39	2	M39753
Pathway	REACTOME_SIGNALING_BY_HIPPO	DVL2 NPHP4	1.37e-03	20	39	2	MM14813
Pathway	REACTOME_SIGNALING_BY_HIPPO	DVL2 NPHP4	1.37e-03	20	39	2	M591
Pathway	WP_FOXA2_PATHWAY	SREBF1 IRS2	1.52e-03	21	39	2	M42579
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	IGKV1-39 IGKV1-12 KLC2 IGKV1D-39 IGKV1D-16 IGKV1D-12 DCTN1 ZNRF2	1.65e-03	828	39	8	M1058
Pathway	REACTOME_HEMOSTASIS	IGKV1-39 IGKV1-12 GATA2 KLC2 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.33e-03	679	39	7	M8395
Pubmed	Human myeloperoxidase in innate and acquired immunity.	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	3.47e-21	18	60	9	20399194
Pubmed	Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome.	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	5.98e-18	20	60	8	10427970
Pubmed	Amino acid sequence of the variable region of M149 mouse myeloma light chain: comparison with the nucleotide sequence of K2 and K3 clones.	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.04e-17	11	60	7	6795447
Pubmed	Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.04e-17	11	60	7	279004
Pubmed	Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.04e-17	11	60	7	6767723
Pubmed	Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.	IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	2.54e-13	36	60	7	11298326
Pubmed	Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene.	IGKV1-39 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-13	1.61e-12	9	60	5	6777049
Pubmed	Structure and implied functions of truncated B-cell receptor mRNAs in early embryo and adult mesenchymal stem cells: Cdelta replaces Cmu in mu heavy chain-deficient mice.	IGKV1-39 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-13	5.55e-11	16	60	5	17124007
Pubmed	The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.	IGKV1-12 IGKV1D-43 IGKV1D-13 IGKV1D-12	1.87e-08	17	60	4	8223863
Pubmed	The human immunoglobulin kappa locus. Characterization of the duplicated O regions.	IGKV1-39 IGKV1-37 IGKV1D-39	4.87e-08	5	60	3	1907917
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGKV1-39 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-13	2.32e-07	77	60	5	15608191
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NEK1 DLG5 UBAP2 ZFP36L2 SH3PXD2A PLEKHG3 KLC2 IRS2 N4BP3 ZNRF2	2.02e-06	861	60	10	36931259
Pubmed	Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells.	SREBF1 AR	2.93e-06	2	60	2	22064655
Pubmed	The Pioneering Role of GATA2 in Androgen Receptor Variant Regulation Is Controlled by Bromodomain and Extraterminal Proteins in Castrate-Resistant Prostate Cancer.	GATA2 AR	2.93e-06	2	60	2	30833300
Pubmed	Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma.	IGKV1-12 IGKV1D-12	2.93e-06	2	60	2	6776411
Pubmed	Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus.	IGKV1-12 IGKV1D-12	2.93e-06	2	60	2	8325334
Pubmed	Sterol regulatory element-binding protein-1c represses the transactivation of androgen receptor and androgen-dependent growth of prostatic cells.	SREBF1 AR	2.93e-06	2	60	2	18245227
Pubmed	Phage display of a human antibody against Clostridium tetani toxin.	IGKV1-39 IGKV1D-39	2.93e-06	2	60	2	7926831
Pubmed	Molecular determinants for enzalutamide-induced transcription in prostate cancer.	GATA2 AR	2.93e-06	2	60	2	31501863
Pubmed	Cloning and characterization of 1116NS19.9 heavy and light chain cDNAs and expression of antibody fragments in Escherichia coli.	IGKV1-12 IGKV1D-12	2.93e-06	2	60	2	8372513
Pubmed	Ganoderma tsugae Inhibits the SREBP-1/AR Axis Leading to Suppression of Cell Growth and Activation of Apoptosis in Prostate Cancer Cells.	SREBF1 AR	2.93e-06	2	60	2	30301150
Pubmed	SREBF1 Activity Is Regulated by an AR/mTOR Nuclear Axis in Prostate Cancer.	SREBF1 AR	8.77e-06	3	60	2	29784665
Pubmed	Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice.	SREBF1 IRS2	8.77e-06	3	60	2	10949029
Pubmed	Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.	IGKV1-39 IGKV1D-39	8.77e-06	3	60	2	6091049
Pubmed	Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.	GATA2 AR	8.77e-06	3	60	2	28038451
Pubmed	CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2.	GATA2 AR	8.77e-06	3	60	2	23887938
Pubmed	Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells.	SREBF1 AR	8.77e-06	3	60	2	20071336
Pubmed	Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5.	DLG5 SH3PXD2A	8.77e-06	3	60	2	28390157
Pubmed	FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression.	GATA2 AR	8.77e-06	3	60	2	26751772
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	NEK1 ZC3H12A VPS37A EIF4ENIF1 ZFP36L2 DVL2 IRS2 N4BP3 ZNRF2 TFE3	1.05e-05	1038	60	10	26673895
Pubmed	Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism.	IGKV1-12 IGKV1D-12	1.75e-05	4	60	2	6264318
Pubmed	GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer.	GATA2 AR	1.75e-05	4	60	2	22021428
Pubmed	Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects.	SREBF1 IRS2	1.75e-05	4	60	2	23147115
Pubmed	Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.	DVL2 IRS2	1.75e-05	4	60	2	24616100
Pubmed	A large section of the gene locus encoding human immunoglobulin variable regions of the kappa type is duplicated.	IGKV1D-13 IGKV1D-12	1.75e-05	4	60	2	3927006
Pubmed	The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4.	NEFM GATA2	1.75e-05	4	60	2	10556076
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EIF4ENIF1 ZFP36L2 RALGPS1 HECTD4 GATA2 SREBF1 IRS2 NPHP4 DCTN1 TFE3	1.79e-05	1105	60	10	35748872
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	IGKV1-39 IGKV1-27 MIDN KLC2 IRS2 IGKV1D-39 IGKV1D-16	2.34e-05	497	60	7	36774506
Pubmed	Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type.	IGKV1-13 IGKV1-12	2.92e-05	5	60	2	6086934
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	DLG5 UBAP2 DVL2 KLC2 DCTN1	3.65e-05	216	60	5	31519766
Pubmed	Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway.	PHLPP1 AR	4.37e-05	6	60	2	25216524
Pubmed	TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.	IRS2 TFE3	4.37e-05	6	60	2	16327801
Pubmed	Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.	ZC3H12A ZFP36L2	6.11e-05	7	60	2	18682727
Pubmed	Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding.	VPS37A ABI2	6.11e-05	7	60	2	15509564
Pubmed	GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.	GATA2 AR	6.11e-05	7	60	2	18212046
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	IGKV1-12 KLC2 IRS2 N4BP3 TFE3	8.01e-05	255	60	5	15324660
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	NEFM NEK1 UBAP2 EIF4ENIF1 ZFP36L2 ADRM1 SH3PXD2A NPHP4 DCTN1 ZNRF2	8.07e-05	1321	60	10	27173435
Pubmed	Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.	NEFM DVL2	8.14e-05	8	60	2	15454084
Pubmed	PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation.	CSF1R GATA2	8.14e-05	8	60	2	8777716
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	DLG5 UBAP2 EIF4ENIF1 DVL2 PHLPP1	8.16e-05	256	60	5	33397691
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NEFM NEK1 EIF4ENIF1 DVL2 IRS2 DCTN1	8.42e-05	418	60	6	34709266
Pubmed	Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.	IRS2 AR	1.05e-04	9	60	2	17662267
Pubmed	Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus.	NEFM GATA2	1.05e-04	9	60	2	12885554
Pubmed	Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.	NEFM DLG5	1.59e-04	11	60	2	25232112
Pubmed	Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system.	NEFM GATA2	1.59e-04	11	60	2	10357893
Pubmed	Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a.	NEFM DVL2	1.59e-04	11	60	2	25190059
Pubmed	USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.	PHLPP1 AR	2.26e-04	13	60	2	28363942
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NEFM UBAP2 KCNA3 ABI2 HECTD4 DVL2 DCTN1 UNC13A	2.40e-04	963	60	8	28671696
Pubmed	The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.	NEFM DVL2	3.46e-04	16	60	2	22771245
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	NEFM KCNA3	3.46e-04	16	60	2	28283561
Pubmed	Loss of transforming growth factor-beta 2 leads to impairment of central synapse function.	NEFM UNC13A	4.40e-04	18	60	2	18854036
Pubmed	A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.	ZFP36L2 KLC2 IRS2	4.67e-04	87	60	3	17979178
Pubmed	T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.	NEFM GATA2	6.02e-04	21	60	2	17119020
Pubmed	Jak2 is essential for signaling through a variety of cytokine receptors.	CSF1R GATA2	6.02e-04	21	60	2	9590173
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	EIF4ENIF1 ADRM1 DVL2 SREBF1 KLC2 CACNA1G	6.26e-04	608	60	6	16713569
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DLG5 EIF4ENIF1 ABI2 ZNF185 DVL2 KLC2 DCTN1	6.50e-04	853	60	7	28718761
Pubmed	Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.	CSF1R GATA2	6.61e-04	22	60	2	9324354
Pubmed	AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.	CSF1R GATA2	6.61e-04	22	60	2	9811459
Pubmed	Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons.	NEFM GATA2	7.23e-04	23	60	2	35815619
Pubmed	Local regulation of fat metabolism in peripheral nerves.	NEFM SREBF1	7.23e-04	23	60	2	14522948
Pubmed	Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons.	NEFM GATA2	7.88e-04	24	60	2	14534138
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DLG5 PLEKHG3 PHLPP1	8.07e-04	105	60	3	9628581
Pubmed	Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.	IRS2 AR	8.56e-04	25	60	2	18992263
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	NEFM UNC13A	9.26e-04	26	60	2	17124501
Pubmed	Retinoic acid deficiency impairs the vestibular function.	NEFM GATA2	9.26e-04	26	60	2	23536097
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	EIF4ENIF1 ZFP36L2 SH3PXD2A KLC2 IRS2	1.04e-03	446	60	5	24255178
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ZNF703 EIF4ENIF1 ZFP36L2	1.28e-03	123	60	3	26912792
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NEFM ZNF185 GATA2 SREBF1 NDRG3 TFE3	1.38e-03	709	60	6	22988430
Pubmed	RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.	NEFM IRS2	1.40e-03	32	60	2	20111592
Pubmed	HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.	AR TFE3	1.40e-03	32	60	2	11748221
Pubmed	Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions.	CSF1R AR	1.49e-03	33	60	2	36922518
Pubmed	Amyotrophic Lateral Sclerosis Overview	NEK1 DCTN1	1.49e-03	33	60	2	20301623
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	VPS37A DCTN1 AR	1.60e-03	133	60	3	15604093
Interaction	YWHAB interactions	NEK1 DLG5 ZFP36L2 ADRM1 ABI2 SH3PXD2A PLEKHG3 RALGPS1 HECTD4 DVL2 KLC2 IRS2 N4BP3 DCTN1 TFE3	4.13e-08	1014	54	15	int:YWHAB
Interaction	YWHAQ interactions	NEK1 DLG5 UBAP2 ZFP36L2 ADRM1 SH3PXD2A PLEKHG3 HECTD4 DVL2 KLC2 IRS2 N4BP3 ZNRF2 AR TFE3	1.48e-07	1118	54	15	int:YWHAQ
Interaction	YWHAG interactions	IGKV1-12 NEK1 DLG5 UBAP2 KCNA3 ZFP36L2 SH3PXD2A PLEKHG3 HECTD4 DVL2 KLC2 IRS2 N4BP3 ZNRF2 TFE3	6.08e-07	1248	54	15	int:YWHAG
Interaction	YWHAH interactions	NEK1 DLG5 UBAP2 ZFP36L2 ABI2 SH3PXD2A PLEKHG3 HECTD4 KLC2 IRS2 N4BP3 DCTN1 ZNRF2 TFE3	8.17e-07	1102	54	14	int:YWHAH
Interaction	YWHAE interactions	NEK1 DLG5 MIDN KCNA3 ZFP36L2 ABI2 SH3PXD2A PLEKHG3 DVL2 KLC2 IRS2 N4BP3 DCTN1 TFE3	3.82e-06	1256	54	14	int:YWHAE
Interaction	YWHAZ interactions	NEFM NEK1 DLG5 ZFP36L2 ABI2 SH3PXD2A PLEKHG3 HECTD4 KLC2 IRS2 N4BP3 DCTN1 AR TFE3	6.73e-06	1319	54	14	int:YWHAZ
Interaction	HOOK3 interactions	DLG5 EIF4ENIF1 ABI2 DVL2 KLC2 DCTN1	1.63e-05	202	54	6	int:HOOK3
Interaction	KRT8 interactions	NEFM DLG5 EIF4ENIF1 KRT71 PHLPP1 NPHP4 DCTN1 AR	2.12e-05	441	54	8	int:KRT8
Interaction	CTDSP2 interactions	NEK1 CSF1R N4BP3 AR	2.44e-05	63	54	4	int:CTDSP2
Interaction	HDAC1 interactions	NEFM NEK1 KCNA3 EIF4ENIF1 ADRM1 DVL2 SREBF1 PHLPP1 IRS2 DCTN1 AR TFE3	2.88e-05	1108	54	12	int:HDAC1
Interaction	ARID5B interactions	GATA2 DVL2 AR TFE3	3.11e-05	67	54	4	int:ARID5B
Interaction	KDM1A interactions	NEFM NEK1 DLG5 VPS37A EIF4ENIF1 PLEKHG3 GATA2 DVL2 IRS2 DCTN1 AR	3.28e-05	941	54	11	int:KDM1A
Interaction	FBXO22 interactions	IGKV1-39 IGKV1-27 MIDN KLC2 PHLPP1 IRS2 IGKV1D-39 IGKV1D-16	8.87e-05	540	54	8	int:FBXO22
Interaction	RPL23 interactions	PWP1 MIDN KCNA3 DVL2 PPM1M AR TFE3 MUC20	8.87e-05	540	54	8	int:RPL23
Interaction	MARK2 interactions	DLG5 KCNA3 SH3PXD2A DVL2 PHLPP1 DCTN1	8.93e-05	274	54	6	int:MARK2
Interaction	KRT19 interactions	NEFM DLG5 EIF4ENIF1 KRT71 ABI2 DVL2	1.05e-04	282	54	6	int:KRT19
Interaction	ZNF703 interactions	ZNF703 MIDN GATA2 CCDC85A	1.13e-04	93	54	4	int:ZNF703
Interaction	DSP interactions	NEFM MIDN KCNA3 PHLPP1 NPHP4 AR TFE3	1.29e-04	423	54	7	int:DSP
Interaction	EPPK1 interactions	NEFM KCNA3 PHLPP1 NPHP4 AR	1.50e-04	189	54	5	int:EPPK1
Interaction	CTTN interactions	NEFM DLG5 KCNA3 SH3PXD2A PLEKHG3 PHLPP1 NPHP4	1.89e-04	450	54	7	int:CTTN
Interaction	NEK5 interactions	NEK1 DVL2	2.51e-04	9	54	2	int:NEK5
Interaction	COL27A1 interactions	KCNA3 DVL2	2.51e-04	9	54	2	int:COL27A1
Interaction	KIAA1217 interactions	ABI2 PHLPP1 DCTN1 AR	2.55e-04	115	54	4	int:KIAA1217
Interaction	CDK6 interactions	EIF4ENIF1 ABI2 PPM1M PHLPP1 AR	2.73e-04	215	54	5	int:CDK6
Interaction	JUP interactions	MIDN KCNA3 KLC2 PHLPP1 NPHP4 AR TFE3	2.98e-04	485	54	7	int:JUP
Interaction	PHF21A interactions	NEFM NEK1 EIF4ENIF1 DVL2 IRS2 AR	3.02e-04	343	54	6	int:PHF21A
Interaction	ZC3H15 interactions	PWP1 KCNA3 PHLPP1 DCTN1	3.20e-04	122	54	4	int:ZC3H15
Interaction	CTNNA1 interactions	DLG5 MIDN KCNA3 EIF4ENIF1 ZFP36L2 AR	3.21e-04	347	54	6	int:CTNNA1
Interaction	MAP7D3 interactions	KCNA3 PHLPP1 DCTN1 CCDC85A	3.30e-04	123	54	4	int:MAP7D3
Interaction	CLTC interactions	MIDN CSF1R ADRM1 KLC2 PHLPP1 DCTN1 AR TFE3	3.31e-04	655	54	8	int:CLTC
Interaction	RCOR1 interactions	NEFM NEK1 EIF4ENIF1 GATA2 DVL2 DCTN1 AR	3.33e-04	494	54	7	int:RCOR1
Cytoband	2p12	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	4.49e-22	117	60	13	2p12
Cytoband	Ensembl 112 genes in cytogenetic band chr2p11	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.36e-18	213	60	13	chr2p11
GeneFamily	Immunoglobulin kappa locus at 2p11.2	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	6.96e-21	83	44	13	351
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD PLEKHG3 RALGPS1 PHLPP1 IRS2	1.38e-04	206	44	5	682
GeneFamily	Protein phosphatases, Mg2+/Mn2+ dependent	PPM1M PHLPP1	7.69e-04	17	44	2	701
Coexpression	RASHI_RESPONSE_TO_IONIZING_RADIATION_6	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.61e-11	132	59	9	MM996
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP	NEFM MIDN PLEKHG3 AEBP2 PHLPP1 TFE3	5.89e-06	200	59	6	M8705
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2	IGKV1-39 IGKV1-27 IGKV1-12 OLFM4 IGKV1D-39	4.87e-05	163	52	5	Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3	IGKV1-39 IGKV1-27 IGKV1-12 OLFM4 IGKV1D-39	6.82e-05	175	52	5	Arv_SC-H9hpx_500_K3
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5	IGKV1-39 IGKV1-27 IGKV1-6 OLFM4 IGKV1D-39	8.43e-05	183	52	5	Arv_SC_fibroblast_1000_K5
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3	IGKV1-39 IGKV1-27 IGKV1-6 OLFM4 IGKV1D-39	8.43e-05	183	52	5	Arv_SC-HD_1000_K3
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	5.13e-19	194	60	13	6ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	5.49e-19	195	60	13	f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 FCRL1 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	4.12e-17	197	60	12	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	IPF-Lymphoid-B_Plasma\|IPF / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-37 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	6.94e-16	176	60	11	e4f33f6cd140dd4fa3002bcd65ac8005d27865d1
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	2.30e-15	196	60	11	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	8.92e-14	190	60	10	79ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	8.92e-14	190	60	10	18762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.04e-13	193	60	10	34f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.04e-13	193	60	10	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.22e-13	196	60	10	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.22e-13	196	60	10	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-37 IGKV1-12 KCNA3 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	2.66e-12	180	60	9	e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCell	Biopsy_Other_PF-Immune-Plasma_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	5.47e-12	195	60	9	d0305c6a68c9e361507b04db94f86873085d49b3
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 FCRL1 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	6.00e-12	197	60	9	2662138671262b30508c5759038bcdcfe6551696
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	5.18e-11	162	60	8	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV1D-8	5.18e-11	162	60	8	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	Control-Lymphoid-B_Plasma\|Control / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	8.37e-11	172	60	8	61e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell	COPD-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	9.60e-11	175	60	8	d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.15e-10	179	60	8	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-12 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.50e-10	185	60	8	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-12 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.50e-10	185	60	8	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGKV1-27 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.56e-10	186	60	8	e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-27 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	1.93e-10	191	60	8	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-37 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-12 IGKV1D-8	2.18e-10	194	60	8	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-8	2.27e-10	195	60	8	13f4ee21568fd747608412d33559d10561dbb3c8
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-12	2.27e-10	195	60	8	df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCell	343B-Lymphocytic-Plasma_cell-\|343B / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-8	1.82e-09	157	60	7	554ddbaf83f5d6eb4669c673efdbb28fd87e2ba8
ToppCell	343B-Lymphocytic-Plasma_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-8	1.82e-09	157	60	7	2cb3deb5313ce734710c601935ca318e4179077e
ToppCell	normal_Lung-B_lymphocytes-MALT_B_cells\|normal_Lung / Location, Cell class and cell subclass	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.99e-09	159	60	7	fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-27 IGKV1-6 DDX3Y IGKV1D-43 IGKV1D-13 IGKV1D-12 IGKV1D-8	2.27e-09	162	60	7	b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-12	2.80e-09	167	60	7	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-12	2.80e-09	167	60	7	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	10x5'-GI_large-bowel\|World / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-8	2.92e-09	168	60	7	1290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCell	wk_08-11-Hematologic_Lymphocytic-B\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	IGKV1-39 IGKV1-13 FCRL1 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-8	3.44e-09	172	60	7	d1ab8f493b70ec995281f9fb0991f1d3aa7b928f
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-37 CSF1R ZNF185 IGKV1D-39 IGKV1D-8 CCDC85A	3.58e-09	173	60	7	b335ca2a247156eba821943b2b9fc9922230b409
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-8	3.58e-09	173	60	7	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-12	4.03e-09	176	60	7	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	IPF-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-37 IGKV1-13 IGKV1-12 IGKV1D-43 IGKV1D-12 IGKV1D-8	4.03e-09	176	60	7	cc0cab6487df6867b529596ec94f55d31aa6ca36
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGKV1-27 IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12	4.03e-09	176	60	7	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGKV1-27 IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12	4.03e-09	176	60	7	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGKV1-39 IGKV1-37 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-8	4.19e-09	177	60	7	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	4.53e-09	179	60	7	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	4.53e-09	179	60	7	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	5.28e-09	183	60	7	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells\|Liver / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-12 IGKV1D-39 IGKV1D-13 IGKV1D-12	5.49e-09	184	60	7	6f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGKV1-39 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	6.61e-09	189	60	7	5a42be62552d912d0abf68f00d75ac80bbd69f2c
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-27 IGKV1-12 KCNA3 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13	7.11e-09	191	60	7	da4062a0f6d0af6d330acf11da216c64b0fa7c73
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 FCRL1 IGKV1D-39 IGKV1D-37	9.11e-09	198	60	7	79c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCell	390C-Lymphocytic-Plasma_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8	6.77e-08	156	60	6	4f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell	390C-Lymphocytic-Plasma_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8	6.77e-08	156	60	6	0de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCell	343B-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-16	9.10e-08	164	60	6	cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell	343B-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-16	9.10e-08	164	60	6	e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCell	390C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8	9.78e-08	166	60	6	4ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell	390C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8	9.78e-08	166	60	6	35f6ae2664935dda0d883b32a050ced843204f2d
ToppCell	metastatic_Brain-B_lymphocytes-Plasma_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-8	1.13e-07	170	60	6	53634da9e9c72f6400639954c286c6e38ea5a188
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-37 IGKV1D-39 IGKV1D-16 IGKV1D-8 CCDC85A	1.25e-07	173	60	6	62abaaaf48cabd1423f17fb27c33b75ea88867f4
ToppCell	10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells\|bone_marrow / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-27 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-13	1.25e-07	173	60	6	300904fd35536a69be81d76fe33fe16544523ceb
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-37 IGKV1D-39 IGKV1D-16 IGKV1D-8 CCDC85A	1.25e-07	173	60	6	09cd878c33534bd476d6a4880f5582076189da8c
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-6 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.43e-07	177	60	6	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-13 IGKV1D-12	1.43e-07	177	60	6	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-6 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.43e-07	177	60	6	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-6 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV1D-8	1.43e-07	177	60	6	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-13 IGKV1D-12	1.43e-07	177	60	6	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-12 FCRL1 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.48e-07	178	60	6	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-13	1.63e-07	181	60	6	e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell	10x5'-Lung-Lymphocytic_B\|Lung / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-12 FCRL1 IGKV1D-39 IGKV1D-12 IGKV1D-8	1.68e-07	182	60	6	310f94437d197eaaaf6e30e68063b33e94befe77
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 FCRL1 IGKV1D-39	1.74e-07	183	60	6	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 FCRL1 IGKV1D-39	1.74e-07	183	60	6	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-27 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.86e-07	185	60	6	0fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-27 IGKV1-6 IGKV1D-39 IGKV1D-13 IGKV1D-8	1.86e-07	185	60	6	79edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1D-39 IGKV1D-12 IGKV1D-8	1.91e-07	186	60	6	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGKV1-6 IGKV1D-39 IGKV1D-37 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.04e-07	188	60	6	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13	2.45e-07	194	60	6	f902e7eb7e7fbb129c1a6e4160166f16798abaf6
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	2.61e-07	196	60	6	b3d5540fe8ab9a9cbb9ab5350f5cb0e1aae93584
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1-12 FCRL1 IGKV1D-39 IGKV1D-13	2.69e-07	197	60	6	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	Biopsy_Control_(H.)-Immune-Plasma_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-8	2.69e-07	197	60	6	275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-13 IGKV1D-8	2.69e-07	197	60	6	b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-27 IGKV1-12 FCRL1 IGKV1D-43 IGKV1D-39	2.77e-07	198	60	6	d51ee880acc5804cd918105fac846a1528333d6c
ToppCell	metastatic_Lymph_Node-B_lymphocytes-Plasma_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-37	1.39e-06	142	60	5	5ba3a33c2ee20be8baaed97536ca6e9d1de6752f
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-6 FCRL1 IGKV1D-39 IGKV1D-8	1.76e-06	149	60	5	2cd860b96ed4be4d26844085d464961c1418054a
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-37	2.42e-06	159	60	5	204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCell	10x5'-Lung-Lymphocytic_B-Naive_B_cells\|Lung / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-12 FCRL1 IGKV1D-39 IGKV1D-13	2.90e-06	165	60	5	1776e7db80d7cf6b449fa8635a111705a59231b4
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-12	3.26e-06	169	60	5	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-12	3.35e-06	170	60	5	ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-12	3.35e-06	170	60	5	d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell	Control-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1D-43 IGKV1D-39	3.35e-06	170	60	5	fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-12	3.35e-06	170	60	5	52787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-16	3.65e-06	173	60	5	0ca2169a275404118038c0489a48062879488765
ToppCell	Plasma_cells\|World / lung cells shred on cell class, cell subclass, sample id	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-8	3.65e-06	173	60	5	52a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCell	10x5'-bone_marrow-Lymphocytic_B_plasma\|bone_marrow / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-13 IGKV1-6 IGKV1D-39 IGKV1D-13	3.75e-06	174	60	5	b1931028cf80af5eff6da15d7f0196205f17926f
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-12 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.86e-06	175	60	5	c3d3f11602379aaba65842a98835299e54fccd84
ToppCell	COPD-Lymphoid-B_Plasma\|COPD / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1D-39 IGKV1D-8	4.08e-06	177	60	5	1b872d3b1e0fca138362098590a634d748dfca60
ToppCell	BAL-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-39 IGKV1-37 IGKV1-12 FCRL1 IGKV1D-12	4.20e-06	178	60	5	499640cfb1063aa40343ec1563e40fe4645466fb
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-39 IGKV1-37 IGKV1-12 FCRL1 IGKV1D-12	4.20e-06	178	60	5	851fdcf1451880a048885cc6677b4edfff6aee4c
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-39 IGKV1-37 IGKV1-12 FCRL1 IGKV1D-12	4.20e-06	178	60	5	1a3b3b73e81ceb26cec8153cd1bdd7b446887a71
ToppCell	normal_Lymph_Node-B_lymphocytes-Plasma_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	IGKV1-27 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-12	4.55e-06	181	60	5	949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-39 IGKV1-12 IGKV1-6 FCRL1 IGKV1D-39	4.55e-06	181	60	5	700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell	metastatic_Lymph_Node-B_lymphocytes-Plasma_cells\|B_lymphocytes / Location, Cell class and cell subclass	IGKV1-37 IGKV1-27 IGKV1-12 IGKV1D-39 IGKV1D-37	4.68e-06	182	60	5	27d1688fdfc570cedd233aa7030bce7d9b604d42
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	IGKV1-13 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	4.80e-06	183	60	5	a6866951866373a1029e04818f4a4a31278c409d
ToppCell	368C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-8	4.80e-06	183	60	5	7733cf919eda146efe41c93990658ce92db73aa8
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	CSF1R RALGPS1 DVL2 IRS2 N4BP3 AR	3.32e-06	195	48	6	7361_UP
Disease	Amyotrophic Lateral Sclerosis	NEK1 DCTN1 UNC13A	1.40e-04	58	51	3	C0002736
Disease	Insulin Sensitivity	SREBF1 IRS2 AR	1.55e-04	60	51	3	C0920563
Disease	Insulin Resistance	SREBF1 IRS2 AR	1.55e-04	60	51	3	C0021655
Disease	Amyotrophic Lateral Sclerosis With Dementia	NEK1 UNC13A	1.15e-03	29	51	2	C0393554
Disease	Amyotrophic Lateral Sclerosis, Guam Form	NEK1 UNC13A	1.32e-03	31	51	2	C0543859
Disease	amyotrophic lateral sclerosis (is_implicated_in)	NEK1 UNC13A	1.41e-03	32	51	2	DOID:332 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPTGSSRYASSGELS	UNC13A	256	Q9UPW8
ETRSLSPGAASSSSG	AEBP2	136	Q6ZN18
AGASSSLGPSGSASA	DCTN1	161	Q14203
SLGPSGSASAGELSS	DCTN1	166	Q14203
SEGSRSSGSTRSDGG	DVL2	586	O14641
YSSSGSSGGSHPSSR	ABI2	241	Q9NYB9
GSTLSLSRASGGSSP	CCDC60	236	Q8IWA6
DLAGPSAGSGSARFS	RALGPS1	301	Q5JS13
STSSSLGSGESPFSR	NDRG3	331	Q9UGV2
PSRFSGSGSGTDFTL	IGKV1D-39	81	P04432
PSRFSGSGSGTDFTL	IGKV1D-12	81	P01611
LGSGGTIAPSSFSSR	NEK1	426	Q96PY6
SGSSAGPSTRRADTA	MUC20	21	Q8N307
PSRFSGSGSGTDYTL	IGKV1D-43	81	A0A0B4J1Z2
PSRFSGSGSGTDFTL	IGKV1D-37	81	P0DSN7
PSRFSGSGSGTDFTL	IGKV1D-8	81	A0A087WSZ0
PSRFSGSGSGTDFTL	IGKV1D-13	81	A0A0B4J2D9
GSNSLPSSARLGSSS	DLG5	1251	Q8TDM6
TSGSRAGASSFSDPF	KCNA3	281	P22001
SSSGRAREASGAPTS	AR	206	P10275
SSATRSLFGGTSGLS	HECTD4	151	Q9Y4D8
SRFSGGSLLTTGSSR	NPHP4	856	O75161
PGGTGLSDSRTLSSS	KLC2	596	Q9H0B6
SSLGSGTPGTSSDSR	IRS2	956	Q9Y4H2
ASPASSSAGGSAARG	GATA2	191	P23769
LPSSSRSGGSGSSSS	CSF1R	926	P07333
SRRTSSSGSAEPGAA	CACNA1G	1066	O43497
SRSAPSGGGASFNLS	FCRL1	251	Q96LA6
SFRLSSGADGSNSSP	CCDC85A	486	Q96PX6
PSRFSGSGSGTDFTL	IGKV1-6	81	A0A0C4DH72
PSRFSGSGSGTDFTL	IGKV1-12	81	A0A0C4DH73
PSRFSGSGSGTDFTL	IGKV1-13	81	P0DP09
PSRFSGSGSGTDFTL	IGKV1-27	81	A0A075B6S5
PSRFSGSGSGTDFTL	IGKV1-37	81	A0A075B6S9
PSRFSGSGSGTDFTL	IGKV1-39	81	P01597
SSSSGFGASRGSSSR	DDX3Y	606	O15523
SDGSGSAGSSLASSP	DRP2	881	Q13474
RSDSSSSGGGGSPSE	MIDN	426	Q504T8
SGGSGSGSSPFLDLT	PSD	736	A5PKW4
SSGFGSPRLVSRSSS	PLEKHG3	626	A1L390
RSGSSSSRSLGSGGS	OLFM4	51	Q6UX06
FQSSPLSLGSRGSGS	SREBF1	436	P36956
FSNPSRSGSRSSSLG	EIF4ENIF1	341	Q9NRA8
GSSGPPGSSSSSSSR	ADRM1	196	Q16186
ARNSSISGPFGSRSS	PWP1	481	Q13610
RAYSGSDLPSSSSGG	ZNRF2	16	Q8NHG8
GGTPASASSSSSRAA	UBAP2	771	Q5T6F2
ASSSSSSPGGSRGGS	ZNF703	211	Q9H7S9
SGRSLAPSGGSGSSF	ZC3H12A	401	Q5D1E8
TLSASSSAGGSRTPA	TFE3	91	P19532
RGSSGDSDSPGSSSL	SH3PXD2A	636	Q5TCZ1
FLRGSSSSPGAADAS	PPM1M	36	Q96MI6
DRLDPYSSGGGSSSS	PHLPP1	361	O60346
SGSLSSGSLSGSESP	ZFP36L2	461	P47974
PSGRSRATSFSSAGE	ZNF185	56	O15231
GSSRGSLASSRGSLA	WWC3	366	Q9ULE0
ASSSAAGSPGGLTSL	VPS37A	11	Q8NEZ2
SAVLSGGSSSSFRAG	KRT71	21	Q3SY84
PSRFSGSGSGTDFTL	IGKV1D-16	81	P01601
PSLSDSSSGGSFGRS	N4BP3	186	O15049
RSSFSRVSGSPSSGF	NEFM	21	P07197