Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	1.82e-05	9	126	3	GO:0160063
GeneOntologyBiologicalProcess	protein insertion into ER membrane	WNK1 NOMO1 NOMO2 NOMO3	3.68e-05	31	126	4	GO:0045048
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	1.79e-05	9	127	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	7.59e-05	14	127	3	GO:0072379
GeneOntologyCellularComponent	ciliary pocket membrane	EHD3 EHD1	1.09e-04	3	127	2	GO:0020018
GeneOntologyCellularComponent	ciliary pocket	EHD3 EHD1	1.09e-04	3	127	2	GO:0020016
GeneOntologyCellularComponent	T-tubule	CACNB1 OPRK1 SCN1A SCN2A KCNJ11	1.20e-04	79	127	5	GO:0030315
GeneOntologyCellularComponent	periciliary membrane compartment	ADGRV1 KIF17	5.41e-04	6	127	2	GO:1990075
GeneOntologyCellularComponent	recycling endosome membrane	EHD4 EHD3 MICALL1 CLCN4 EHD1	6.11e-04	112	127	5	GO:0055038
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A UNC80	7.13e-04	29	127	3	GO:0034706
GeneOntologyCellularComponent	sarcolemma	CACNB1 OPRK1 SLC8A3 SCN1A SCN2A KCNJ11	1.08e-03	190	127	6	GO:0042383
GeneOntologyCellularComponent	endosome membrane	ATP6V0A1 TSG101 TMEM9B ATP13A2 EHD4 EHD3 MICALL1 CPTP CLCN4 EHD1 ELAPOR1	1.13e-03	602	127	11	GO:0010008
GeneOntologyCellularComponent	cilium	PDGFRA TSPEAR ADGRV1 EFHB QRICH2 DNAH1 EHD3 CLCN4 EHD1 NME5 TSSK1B DNAH6 KIF17 CFAP46	1.13e-03	898	127	14	GO:0005929
GeneOntologyCellularComponent	platelet dense tubular network membrane	EHD1 ATP2A1	1.28e-03	9	127	2	GO:0031095
GeneOntologyCellularComponent	paraspeckles	PSPC1 NONO	1.60e-03	10	127	2	GO:0042382
GeneOntologyCellularComponent	inner dynein arm	DNAH1 DNAH6	1.60e-03	10	127	2	GO:0036156
GeneOntologyCellularComponent	axoneme	EFHB DNAH1 NME5 DNAH6 KIF17 CFAP46	1.68e-03	207	127	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	EFHB DNAH1 NME5 DNAH6 KIF17 CFAP46	1.72e-03	208	127	6	GO:0097014
GeneOntologyCellularComponent	nuclear outer membrane	SYNE1 CPTP UGT2B10	1.84e-03	40	127	3	GO:0005640
GeneOntologyCellularComponent	platelet dense tubular network	EHD1 ATP2A1	1.94e-03	11	127	2	GO:0031094
GeneOntologyCellularComponent	cell-cell contact zone	PKP4 SCN1A SCN2A KCNJ11	2.60e-03	94	127	4	GO:0044291
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.25e-06	4	128	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.25e-06	4	128	3	IPR019008
Domain	EHD_N	EHD4 EHD3 EHD1	3.11e-06	5	128	3	IPR031692
Domain	EHD_N	EHD4 EHD3 EHD1	3.11e-06	5	128	3	PF16880
Domain	Calx_beta	FRAS1 ADGRV1 SLC8A3	1.72e-05	8	128	3	SM00237
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	1.72e-05	8	128	3	IPR013784
Domain	Calx_beta	FRAS1 ADGRV1 SLC8A3	2.56e-05	9	128	3	IPR003644
Domain	Calx-beta	FRAS1 ADGRV1 SLC8A3	2.56e-05	9	128	3	PF03160
Domain	EF-hand-dom_pair	LRRC74A EFHB STAT5A STAT5B EHD4 EHD3 DUOX1 SCN1A MRPS26 EHD1	2.89e-05	287	128	10	IPR011992
Domain	EF-hand_4	EHD4 EHD3 EHD1	3.64e-05	10	128	3	PF12763
Domain	EHD1/EHD3	EHD3 EHD1	4.66e-05	2	128	2	IPR029951
Domain	EH	EHD4 EHD3 EHD1	4.98e-05	11	128	3	PS50031
Domain	EH	EHD4 EHD3 EHD1	4.98e-05	11	128	3	SM00027
Domain	EH_dom	EHD4 EHD3 EHD1	4.98e-05	11	128	3	IPR000261
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	8.55e-05	13	128	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	8.55e-05	13	128	3	2.60.40.1120
Domain	G_DYNAMIN_dom	EHD4 EHD3 EHD1	1.08e-04	14	128	3	IPR030381
Domain	G_DYNAMIN_2	EHD4 EHD3 EHD1	1.08e-04	14	128	3	PS51718
Domain	Dynamin_GTPase	EHD4 EHD3 EHD1	1.35e-04	15	128	3	IPR001401
Domain	Dynamin_SF	EHD4 EHD3 EHD1	1.35e-04	15	128	3	IPR022812
Domain	Dynamin_N	EHD4 EHD3 EHD1	1.35e-04	15	128	3	PF00350
Domain	NOPS	PSPC1 NONO	1.39e-04	3	128	2	IPR012975
Domain	NOPS	PSPC1 NONO	1.39e-04	3	128	2	PF08075
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	1.99e-04	17	128	3	IPR008969
Domain	Aldehyde_DH_NAD(P)	ALDH3A1 ALDH3B2	2.77e-04	4	128	2	IPR012394
Domain	-	LRRC74A EFHB STAT5A STAT5B EHD4 EHD3 DUOX1 EHD1	4.41e-04	261	128	8	1.10.238.10
Domain	Na_trans_cytopl	SCN1A SCN2A	6.87e-04	6	128	2	PF11933
Domain	EPTP	TSPEAR ADGRV1	6.87e-04	6	128	2	PF03736
Domain	EPTP	TSPEAR ADGRV1	6.87e-04	6	128	2	IPR005492
Domain	Na_trans_cytopl	SCN1A SCN2A	6.87e-04	6	128	2	IPR024583
Domain	STAT_TF_DNA-bd_sub	STAT5A STAT5B	9.57e-04	7	128	2	IPR012345
Domain	STAT	STAT5A STAT5B	9.57e-04	7	128	2	IPR001217
Domain	STAT_int	STAT5A STAT5B	9.57e-04	7	128	2	SM00964
Domain	STAT_TF_DNA-bd	STAT5A STAT5B	9.57e-04	7	128	2	IPR013801
Domain	STAT_bind	STAT5A STAT5B	9.57e-04	7	128	2	PF02864
Domain	STAT_int	STAT5A STAT5B	9.57e-04	7	128	2	PF02865
Domain	-	STAT5A STAT5B	9.57e-04	7	128	2	1.10.532.10
Domain	STAT_alpha	STAT5A STAT5B	9.57e-04	7	128	2	PF01017
Domain	-	STAT5A STAT5B	9.57e-04	7	128	2	1.20.1050.20
Domain	STAT_TF_prot_interaction	STAT5A STAT5B	9.57e-04	7	128	2	IPR013799
Domain	STAT_TF_coiled-coil	STAT5A STAT5B	9.57e-04	7	128	2	IPR015988
Domain	EAR	TSPEAR ADGRV1	9.57e-04	7	128	2	IPR009039
Domain	-	STAT5A STAT5B	9.57e-04	7	128	2	2.60.40.630
Domain	EAR	TSPEAR ADGRV1	9.57e-04	7	128	2	PS50912
Domain	STAT_TF_alpha	STAT5A STAT5B	1.27e-03	8	128	2	IPR013800
Domain	Chorein_N	ATG2A VPS13D	1.27e-03	8	128	2	PF12624
Domain	VPS13_N	ATG2A VPS13D	1.27e-03	8	128	2	IPR026854
Domain	Na_channel_asu	SCN1A SCN2A	2.02e-03	10	128	2	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A	2.02e-03	10	128	2	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A	2.02e-03	10	128	2	PF06512
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH6	4.02e-03	14	128	2	IPR024317
Domain	Dynein_HC_stalk	DNAH1 DNAH6	4.02e-03	14	128	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH1 DNAH6	4.02e-03	14	128	2	IPR013602
Domain	DHC_N2	DNAH1 DNAH6	4.02e-03	14	128	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH6	4.02e-03	14	128	2	IPR011704
Domain	MT	DNAH1 DNAH6	4.02e-03	14	128	2	PF12777
Domain	AAA_8	DNAH1 DNAH6	4.02e-03	14	128	2	PF12780
Domain	AAA_5	DNAH1 DNAH6	4.02e-03	14	128	2	PF07728
Domain	Growth_fac_rcpt_	FRAS1 EPHA6 STAB1 MEGF6 ELAPOR1	4.43e-03	156	128	5	IPR009030
Domain	DHC_fam	DNAH1 DNAH6	4.62e-03	15	128	2	IPR026983
Domain	Dynein_heavy	DNAH1 DNAH6	4.62e-03	15	128	2	PF03028
Domain	Dynein_heavy_dom	DNAH1 DNAH6	4.62e-03	15	128	2	IPR004273
Domain	fn3	EPHA6 COL20A1 ROBO3 SDK1 IL27RA	5.19e-03	162	128	5	PF00041
Domain	Ald_DH_CS_GLU	ALDH3A1 ALDH3B2	5.25e-03	16	128	2	IPR029510
Domain	Ald_DH_CS_CYS	ALDH3A1 ALDH3B2	5.93e-03	17	128	2	IPR016160
Domain	RUN	RUSC1 SNX29	6.64e-03	18	128	2	SM00593
Domain	ALDEHYDE_DEHYDR_CYS	ALDH3A1 ALDH3B2	6.64e-03	18	128	2	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH3A1 ALDH3B2	6.64e-03	18	128	2	PS00687
Domain	Cation_ATPase_N	ATP13A2 ATP2A1	6.64e-03	18	128	2	SM00831
Pubmed	MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.	EHD4 EHD3 MICALL1 EHD1	2.78e-09	6	130	4	19864458
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	5.10e-08	3	130	3	36011023
Pubmed	Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.	EHD4 EHD3 EHD1	5.10e-08	3	130	3	24019528
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	5.10e-08	3	130	3	25576386
Pubmed	C-terminal EH-domain-containing proteins: consensus for a role in endocytic trafficking, EH?	EHD4 EHD3 EHD1	2.04e-07	4	130	3	16155252
Pubmed	EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.	EHD3 MICALL1 EHD1	2.04e-07	4	130	3	27189942
Pubmed	Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function.	EHD4 EHD3 EHD1	2.04e-07	4	130	3	29212907
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	2.04e-07	4	130	3	31833031
Pubmed	Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans.	EHD4 EHD3 EHD1	2.04e-07	4	130	3	17233914
Pubmed	EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.	EHD4 EHD3 EHD1	2.04e-07	4	130	3	10673336
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	2.04e-07	4	130	3	9267806
Pubmed	EH domain proteins regulate cardiac membrane protein targeting.	EHD4 EHD3 EHD1	5.08e-07	5	130	3	20489164
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII FRAS1 TMC6 CHD8 ATG2A WNK1 ATP13A2 MICALL1 CPTP MEGF6 ZNF827 KCNJ11 STRN4 CPSF1 TANC1 ESPL1 RAI1	8.47e-07	1105	130	17	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	PATZ1 BACH2 PKP4 ANGEL1 CHD8 TSG101 CHEK1 CLPX BRWD3 HMG20A TUBGCP6 THRA UBR5 ZNF827 TANC1 UNC80 RAI1	9.70e-07	1116	130	17	31753913
Pubmed	BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.	BACH2 STAT5A STAT5B	1.01e-06	6	130	3	23852341
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 CHD8 ADGRV1 WNK1 STAB1 MEGF6 UBR5 UNC80	2.24e-06	225	130	8	12168954
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	2.82e-06	8	130	3	15257293
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FRAS1 POGLUT3 ATP6V0A1 SYNE1 PKP4 CLPX ECSIT SNX29 AAR2 NOMO1 EHD4 MICALL1 TUBGCP6 UBR5 NOMO2 MRPS26 TANC1 ESPL1 RAD21	2.86e-06	1487	130	19	33957083
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	4.22e-06	9	130	3	36261522
Pubmed	Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains.	PDGFRA STAT5A STAT5B	4.22e-06	9	130	3	9484840
Pubmed	The endocytic recycling regulatory protein EHD1 Is required for ocular lens development.	EHD4 EHD3 EHD1	8.24e-06	11	130	3	26455409
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	8.24e-06	11	130	3	32820719
Pubmed	Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.	STAT5A STAT5B	1.39e-05	2	130	2	23151802
Pubmed	Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.	STAT5A STAT5B	1.39e-05	2	130	2	26999798
Pubmed	Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.	MICALL1 EHD1	1.39e-05	2	130	2	25287187
Pubmed	A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.	STAT5A STAT5B	1.39e-05	2	130	2	31443474
Pubmed	Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site.	ESPL1 RAD21	1.39e-05	2	130	2	31729382
Pubmed	Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.	STAT5A STAT5B	1.39e-05	2	130	2	12377952
Pubmed	Paraspeckles: a novel nuclear domain.	PSPC1 NONO	1.39e-05	2	130	2	11790299
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	1.39e-05	2	130	2	10827969
Pubmed	A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.	STAT5A STAT5B	1.39e-05	2	130	2	21127177
Pubmed	The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.	STAT5A STAT5B	1.39e-05	2	130	2	16289657
Pubmed	Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.	STAT5A STAT5B	1.39e-05	2	130	2	25552366
Pubmed	Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.	STAT5A STAT5B	1.39e-05	2	130	2	25470773
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	1.39e-05	2	130	2	19694741
Pubmed	Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain.	PDGFRA THRA	1.39e-05	2	130	2	28875931
Pubmed	Constitutively active Stat5A and Stat5B promote adipogenesis.	STAT5A STAT5B	1.39e-05	2	130	2	21431790
Pubmed	Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.	STAT5A STAT5B	1.39e-05	2	130	2	28500076
Pubmed	STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.	STAT5A STAT5B	1.39e-05	2	130	2	21826656
Pubmed	Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.	STAT5A STAT5B	1.39e-05	2	130	2	7720707
Pubmed	STAT5A and STAT5B have opposite correlations with drug response gene expression.	STAT5A STAT5B	1.39e-05	2	130	2	27264955
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	1.39e-05	2	130	2	1317301
Pubmed	Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.	STAT5A STAT5B	1.39e-05	2	130	2	22159083
Pubmed	STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.	STAT5A STAT5B	1.39e-05	2	130	2	20008792
Pubmed	STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.	STAT5A STAT5B	1.39e-05	2	130	2	33199496
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	1.39e-05	2	130	2	31439038
Pubmed	HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells.	BACH2 STAT5B	1.39e-05	2	130	2	28887441
Pubmed	SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.	EHD3 EHD1	1.39e-05	2	130	2	26226295
Pubmed	Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.	ESPL1 RAD21	1.39e-05	2	130	2	11509732
Pubmed	The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.	STAT5A STAT5B	1.39e-05	2	130	2	16502315
Pubmed	Stat5: an essential regulator of mast cell biology.	STAT5A STAT5B	1.39e-05	2	130	2	12217382
Pubmed	Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.	STAT5A STAT5B	1.39e-05	2	130	2	31599926
Pubmed	DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.	STAT5A STAT5B	1.39e-05	2	130	2	10594041
Pubmed	UBR5 is a novel regulator of WNK1 stability.	WNK1 UBR5	1.39e-05	2	130	2	35442829
Pubmed	Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.	STAT5A STAT5B	1.39e-05	2	130	2	21036145
Pubmed	Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.	STAT5A STAT5B	1.39e-05	2	130	2	10486277
Pubmed	Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.	STAT5A STAT5B	1.39e-05	2	130	2	16840779
Pubmed	The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.	STAT5A STAT5B	1.39e-05	2	130	2	15128421
Pubmed	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.	STAT5A STAT5B	1.39e-05	2	130	2	30377054
Pubmed	Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.	STAT5A STAT5B	1.39e-05	2	130	2	23565285
Pubmed	Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.	STAT5A STAT5B	1.39e-05	2	130	2	32790723
Pubmed	In vivo identification of novel STAT5 target genes.	STAT5A STAT5B	1.39e-05	2	130	2	18492722
Pubmed	Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.	STAT5A STAT5B	1.39e-05	2	130	2	10066807
Pubmed	Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.	STAT5A STAT5B	1.39e-05	2	130	2	10835485
Pubmed	Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.	STAT5A STAT5B	1.39e-05	2	130	2	35464049
Pubmed	Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.	STAT5A STAT5B	1.39e-05	2	130	2	18286195
Pubmed	Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.	STAT5A STAT5B	1.39e-05	2	130	2	23773921
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	1.39e-05	2	130	2	15249644
Pubmed	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.	STAT5A STAT5B	1.39e-05	2	130	2	8631883
Pubmed	Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.	STAT5A STAT5B	1.39e-05	2	130	2	11030348
Pubmed	Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.	STAT5A STAT5B	1.39e-05	2	130	2	24878107
Pubmed	Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.	STAT5A STAT5B	1.39e-05	2	130	2	12847485
Pubmed	Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.	STAT5A STAT5B	1.39e-05	2	130	2	12835478
Pubmed	Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.	STAT5A STAT5B	1.39e-05	2	130	2	7568026
Pubmed	Identification of STAT5A and STAT5B target genes in human T cells.	STAT5A STAT5B	1.39e-05	2	130	2	24497979
Pubmed	Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog.	PSPC1 NONO	1.39e-05	2	130	2	25100870
Pubmed	Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.	STAT5A STAT5B	1.39e-05	2	130	2	17536022
Pubmed	STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.	STAT5A STAT5B	1.39e-05	2	130	2	17382296
Pubmed	STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.	STAT5A STAT5B	1.39e-05	2	130	2	17911616
Pubmed	STAT5 signaling in sexually dimorphic gene expression and growth patterns.	STAT5A STAT5B	1.39e-05	2	130	2	10486314
Pubmed	The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.	STAT5A STAT5B	1.39e-05	2	130	2	17599554
Pubmed	MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.	STAT5A STAT5B	1.39e-05	2	130	2	24497923
Pubmed	Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.	STAT5A STAT5B	1.39e-05	2	130	2	24335105
Pubmed	Brain STAT5 signaling modulates learning and memory formation.	STAT5A STAT5B	1.39e-05	2	130	2	29460051
Pubmed	CHD8 haploinsufficiency results in autistic-like phenotypes in mice.	CHD8 REST	1.39e-05	2	130	2	27602517
Pubmed	STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.	STAT5A STAT5B	1.39e-05	2	130	2	28606561
Pubmed	Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.	STAT5A STAT5B	1.39e-05	2	130	2	12393407
Pubmed	The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.	STAT5A STAT5B	1.39e-05	2	130	2	12039059
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	1.39e-05	2	130	2	30693367
Pubmed	Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.	STAT5A STAT5B	1.39e-05	2	130	2	21178171
Pubmed	Eps15 Homology Domain Protein 4 (EHD4) is required for Eps15 Homology Domain Protein 1 (EHD1)-mediated endosomal recruitment and fission.	EHD4 EHD1	1.39e-05	2	130	2	32966336
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	1.39e-05	2	130	2	29649454
Pubmed	Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.	STAT5A STAT5B	1.39e-05	2	130	2	20233708
Pubmed	Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.	STAT5A STAT5B	1.39e-05	2	130	2	16775227
Pubmed	STAT5 isoforms: controversies and clarifications.	STAT5A STAT5B	1.39e-05	2	130	2	17447893
Pubmed	An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.	TSG101 VPS13D	1.39e-05	2	130	2	33623047
Pubmed	Processing, localization, and requirement of human separase for normal anaphase progression.	ESPL1 RAD21	1.39e-05	2	130	2	12672959
Pubmed	EHD proteins are associated with tubular and vesicular compartments and interact with specific phospholipids.	EHD4 EHD1	1.39e-05	2	130	2	17097635
Pubmed	ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein.	TSG101 ATP13A2	1.39e-05	2	130	2	25392495
Pubmed	Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS.	PSPC1 NONO	1.39e-05	2	130	2	32844195
Cytoband	Xp11.4-p11.2	GAGE5 GAGE6	1.18e-04	6	130	2	Xp11.4-p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	PKP4 SCN1A SCN2A TANC1	4.85e-04	127	130	4	chr2q24
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A	8.06e-04	9	87	2	1203
GeneFamily	Fibronectin type III domain containing	EPHA6 COL20A1 ROBO3 SDK1 IL27RA	1.05e-03	160	87	5	555
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 DNAH1 SCN2A UNC79 SDK1 UNC80	1.06e-06	184	128	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 DNAH1 SCN2A UNC79 SDK1 UNC80	1.06e-06	184	128	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 DNAH1 SCN2A UNC79 SDK1 UNC80	1.06e-06	184	128	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 BACH2 SNX29 UBR5 TANC1 UNC79 SDK1	1.23e-06	188	128	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAPSA CACNB1 ADGRV1 DUOX1 MEGF6 SCN1A PLA2G4F	1.41e-06	192	128	7	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDGFRA SYNE1 EHD3 SCN1A SCN2A UNC79 UNC80	1.79e-06	199	128	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SYNE1 ADGRV1 DUOX1 MEGF6 SCN1A PLA2G4F	1.79e-06	199	128	7	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MYH8 EPHA6 ADGRV1 SCN1A UNC80	3.96e-06	145	128	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MUC15 EFHB OPRK1 DNAH1 ALDH3A1 CFAP46	5.01e-06	151	128	6	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MUC15 EFHB OPRK1 DNAH1 ALDH3A1 CFAP46	5.01e-06	151	128	6	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 DNAH1 DNAH6 UNC79 UNC80	9.54e-06	169	128	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL20A1 APMAP QRICH2 HMG20A TUBGCP6 DNAH6	1.16e-05	175	128	6	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	NAPSA SYNE1 ADGRV1 DUOX1 SCN1A PLA2G4F	1.37e-05	180	128	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	PDGFRA PKP4 STRN4 TMEM184B PSPC1	1.39e-05	106	128	5	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	PDGFRA PKP4 STRN4 TMEM184B PSPC1	1.39e-05	106	128	5	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	PDGFRA PKP4 STRN4 TMEM184B PSPC1	1.39e-05	106	128	5	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EPHA6 TSPEAR ADGRV1 OPRK1 TDRD7 CLIP4	1.50e-05	183	128	6	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNK1 FER1L4 ALDH3A1 ALDH3B2 PNOC PCOLCE	1.64e-05	186	128	6	7380af16e537cc49a2bb24ac50663d13c38459a7
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNK1 FER1L4 ALDH3A1 ALDH3B2 PNOC PCOLCE	1.64e-05	186	128	6	d56ccbe26bfddba0e2c54e7c7a5ca7f46fd3d891
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	NAPSA TMC6 SNX29 CLIP4 DUOX1 SCN1A	1.80e-05	189	128	6	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	1.97e-05	192	128	6	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	NAPSA CACNB1 ADGRV1 DUOX1 SCN1A PLA2G4F	1.97e-05	192	128	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Bronchial_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	MUC15 EFHB NME5 DZIP3 DNAH6 CFAP46	2.03e-05	193	128	6	3e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SYNE1 ADGRV1 DUOX1 SCN1A PLA2G4F	2.03e-05	193	128	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.03e-05	193	128	6	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SYNE1 SCN1A PLA2G4F DNAH6 CFAP46	2.03e-05	193	128	6	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SYNE1 ADGRV1 DUOX1 SCN1A PLA2G4F	2.03e-05	193	128	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.09e-05	194	128	6	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.09e-05	194	128	6	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	RNLS SYNE1 TANC1 DNAH6 SDK1 CFAP46	2.15e-05	195	128	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC15 EFHB NME5 DZIP3 DNAH6 CFAP46	2.15e-05	195	128	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LZTS1 SCN2A ELAPOR1 KIF17 UNC80	2.15e-05	195	128	6	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	RNLS SYNE1 TANC1 DNAH6 SDK1 CFAP46	2.15e-05	195	128	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC15 EFHB NME5 DZIP3 DNAH6 CFAP46	2.15e-05	195	128	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC15 EFHB NME5 DZIP3 DNAH6 CFAP46	2.15e-05	195	128	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SYNE1 ADGRV1 DUOX1 SCN1A PLA2G4F	2.21e-05	196	128	6	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.27e-05	197	128	6	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDGFRA COL20A1 ESCO1 EHD3 ZNF517 UNC80	2.27e-05	197	128	6	b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 SCN1A SCN2A UNC79 TARBP1 UNC80	2.34e-05	198	128	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 SCN1A SCN2A UNC79 TARBP1 UNC80	2.34e-05	198	128	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Bronchial-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NAPSA MUC15 ADGRV1 DUOX1 ELAPOR1 ALDH3A1	2.47e-05	200	128	6	d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	SYNE1 EFHB NME5 DZIP3 DNAH6 CFAP46	2.47e-05	200	128	6	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAPSA ADGRV1 DUOX1 MEGF6 ELAPOR1 PLA2G4F	2.47e-05	200	128	6	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NAPSA ADGRV1 DUOX1 MEGF6 ELAPOR1 PLA2G4F	2.47e-05	200	128	6	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	NAPSA ADGRV1 DUOX1 MEGF6 ELAPOR1 PLA2G4F	2.47e-05	200	128	6	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	(09)_Interm._secr.>cil.\|World / shred by cell type by condition	SYNE1 EFHB NME5 DZIP3 ALDH3A1 DNAH6	2.47e-05	200	128	6	3305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCell	(02)_Cycling_Basal_(regeneration)-(3)_72hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	GDPD1 RNLS TCN2 SLC26A1 ELAPOR1	4.14e-05	133	128	5	32c6a00671af309c4b0b90e93549733729684c61
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 QRICH2 CLIP4 PRR14 ATP2A1	5.47e-05	141	128	5	31e0984f09983e83a814424f74c871c1c5a3a789
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 QRICH2 CLIP4 PRR14 ATP2A1	5.47e-05	141	128	5	d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 SLC26A1 EHD3 KCNJ11 ELAPOR1	6.66e-05	147	128	5	22c9605869dd2e789896cd2790ee8def2605de57
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 SLC26A1 EHD3 KCNJ11 ELAPOR1	6.66e-05	147	128	5	ac272595818d25c6b84b107555b3351e912a01a7
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFHB OPRK1 DNAH1 DNAH6 CFAP46	8.56e-05	155	128	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFHB OPRK1 DNAH1 DNAH6 CFAP46	8.56e-05	155	128	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRA ALDH3A1 SDK1 IL27RA PCOLCE	9.94e-05	160	128	5	6215ac6123a295f3c2f033786602a57b2e2e1177
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	POGLUT3 CLIP4 NME5 SDK1 PCOLCE	1.08e-04	163	128	5	e393e5ff885a42b2b44e430d3d5a58f5e50eb732
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MUC15 PKP4 ADGRV1 VPS13D DNAH6	1.08e-04	163	128	5	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	THEMIS2 NAPSA TCN2 STAB1 KCNJ11	1.12e-04	164	128	5	17d5b8bb7c015cf9f0d6e578a0d212eada39cb93
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAPSA RPS6KA1 ROBO3 ATP2A1 UNC79	1.12e-04	164	128	5	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAPSA RPS6KA1 ROBO3 ATP2A1 UNC79	1.12e-04	164	128	5	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PDGFRA COL20A1 ANGEL1 EHD3 MICALL1	1.28e-04	169	128	5	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PDGFRA COL20A1 ANGEL1 EHD3 MICALL1	1.28e-04	169	128	5	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 THRA DZIP3 DHX35 TARBP1	1.39e-04	172	128	5	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA PDGFRA EHD1 ATP2A1 IL27RA	1.43e-04	173	128	5	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PATZ1 BACH2 LZTS1 ELAPOR1 IL27RA	1.68e-04	179	128	5	db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FER1L4 ALDH3A1 ESPL1 CFAP46 PCOLCE	1.77e-04	181	128	5	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB1 MICALL1 MEGF6 PLA2G4F IL27RA	1.86e-04	183	128	5	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MUC15 EFHB NME5 DNAH6 CFAP46	1.86e-04	183	128	5	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MUC15 EFHB NME5 DNAH6 CFAP46	1.86e-04	183	128	5	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	1.91e-04	184	128	5	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	1.91e-04	184	128	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	1.91e-04	184	128	5	2a8338e94937686a148b5433515700ca0f674058
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	THEMIS2 CLIP4 GORASP1 STRN4 TARBP1	1.96e-04	185	128	5	daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFHB EHD3 SLC8A3 ZNF827 LPP	2.01e-04	186	128	5	b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 MEGF6 TANC1 ROBO3 PCOLCE	2.01e-04	186	128	5	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFHB EHD3 SLC8A3 ZNF827 LPP	2.01e-04	186	128	5	cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	2.06e-04	187	128	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	NAPSA ADGRV1 MEGF6 SCN1A PLA2G4F	2.16e-04	189	128	5	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 EPHA6 ADGRV1 OPRK1 CLIP4	2.16e-04	189	128	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFHB NME5 DZIP3 ALDH3A1 DNAH6	2.16e-04	189	128	5	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DNAH6 CFAP46	2.21e-04	190	128	5	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNE1 EFHB NME5 DNAH6 CFAP46	2.21e-04	190	128	5	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	2.21e-04	190	128	5	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB1 MICALL1 MEGF6 PLA2G4F IL27RA	2.21e-04	190	128	5	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MUC15 EFHB NME5 DNAH6 CFAP46	2.27e-04	191	128	5	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC15 EFHB NME5 DNAH6 CFAP46	2.27e-04	191	128	5	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 EPHA6 ADGRV1 OPRK1 ELAPOR1	2.27e-04	191	128	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	2.27e-04	191	128	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MUC15 EFHB NME5 DNAH6 CFAP46	2.27e-04	191	128	5	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	NAPSA ADGRV1 DUOX1 SCN1A PLA2G4F	2.27e-04	191	128	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC15 EFHB NME5 DNAH6 CFAP46	2.27e-04	191	128	5	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHEK1 ALDH3A1 ESPL1 UNC79 SDK1	2.27e-04	191	128	5	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	NAPSA ADGRV1 DUOX1 MEGF6 PLA2G4F	2.27e-04	191	128	5	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MUC15 EFHB NME5 DNAH6 CFAP46	2.27e-04	191	128	5	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 WNK1 UBR5 SDK1 RAD21	2.32e-04	192	128	5	916fbec1c7ab7969bda711886ac88e877e30c280
Drug	sulindac sulfide; Down 200; 50uM; MCF7; HG-U133A	THEMIS2 CACNB1 FRAS1 ATP6V0A1 RPS6KA1 KATNB1 STAT5A STAB1 EHD1	1.90e-06	197	129	9	308_DN
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN1A SCN2A	5.55e-06	9	121	3	C3502809
Disease	Macrocephaly	CHD8 BRWD3 THRA	1.08e-05	11	121	3	C0221355
Disease	Autism Spectrum Disorders	GPR50 CHD8 SCN1A UNC80 RAI1	2.69e-05	85	121	5	C1510586
Disease	Fetal Alcohol Syndrome	PDGFRA RPS6KA1 REST	4.39e-05	17	121	3	C0015923
Disease	Smith-Magenis syndrome	FLII RAI1	9.95e-05	4	121	2	C0795864
Disease	arthrogryposis multiplex congenita (is_implicated_in)	MYH8 SYNE1	9.95e-05	4	121	2	DOID:0080954 (is_implicated_in)
Disease	colon adenocarcinoma (is_implicated_in)	STAT5A STAT5B UBR5	1.63e-04	26	121	3	DOID:234 (is_implicated_in)
Disease	Sjogren-Larsson syndrome (implicated_via_orthology)	ALDH3A1 ALDH3B2	2.47e-04	6	121	2	DOID:14501 (implicated_via_orthology)
Disease	C-C motif chemokine 22 measurement	BACH2 CX3CL1	2.47e-04	6	121	2	EFO_0020196
Disease	Seizures	KATNB1 REST OPRK1 TBC1D20 SLC8A3 KCNJ11	2.88e-04	218	121	6	C0036572
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	3.46e-04	7	121	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	3.46e-04	7	121	2	C0751057
Disease	Febrile Convulsions	SCN1A SCN2A	5.89e-04	9	121	2	C0009952
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A	7.35e-04	10	121	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A	7.35e-04	10	121	2	DOID:0080422 (implicated_via_orthology)
Disease	Leukemia, Myelocytic, Acute	ACSL6 BACH2 EHD3 LPP RAD21	7.51e-04	173	121	5	C0023467
Disease	Generalized seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0234533
Disease	Clonic Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0234535
Disease	Convulsive Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0751494
Disease	Seizures, Sensory	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0751496
Disease	Non-epileptic convulsion	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0751056
Disease	Atonic Absence Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0751123
Disease	Complex partial seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0149958
Disease	Single Seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0751110
Disease	Nonepileptic Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C3495874
Disease	Visual seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0270824
Disease	Epileptic drop attack	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0270846
Disease	Vertiginous seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0422855
Disease	Gustatory seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0422854
Disease	Seizures, Somatosensory	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0422850
Disease	Olfactory seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0422853
Disease	Seizures, Auditory	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0422852
Disease	Generalized Absence Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C4505436
Disease	Jacksonian Seizure	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C0022333
Disease	Epileptic Seizures	REST OPRK1 SLC8A3 KCNJ11	8.08e-04	101	121	4	C4317109
Disease	Absence Seizures	REST OPRK1 SLC8A3 KCNJ11	8.39e-04	102	121	4	C4316903
Disease	Convulsions	REST OPRK1 SLC8A3 KCNJ11	8.39e-04	102	121	4	C4048158
Disease	Tonic Seizures	REST OPRK1 SLC8A3 KCNJ11	8.39e-04	102	121	4	C0270844
Disease	diabetic nephropathy, type 2 diabetes mellitus	OPRK1 LPP	8.95e-04	11	121	2	EFO_0000401, MONDO_0005148
Disease	Seizures, Focal	REST OPRK1 SLC8A3 KCNJ11	9.02e-04	104	121	4	C0751495
Disease	Myoclonic Seizures	REST OPRK1 SLC8A3 KCNJ11	9.02e-04	104	121	4	C4317123
Disease	Tonic - clonic seizures	REST OPRK1 SLC8A3 KCNJ11	9.02e-04	104	121	4	C0494475
Disease	urate measurement, bone density	FRAS1 SYNE1 BACH2 SNX29 HMG20A DNAH1 LZTS1 LPP DHX35	1.05e-03	619	121	9	EFO_0003923, EFO_0004531
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A	1.07e-03	12	121	2	DOID:0060170 (implicated_via_orthology)
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	1.26e-03	13	121	2	C0751122
Disease	Fetal Alcohol Spectrum Disorders	PDGFRA RPS6KA1	1.26e-03	13	121	2	C2985290
Disease	Genetic chronic primary adrenal insufficiency	BACH2 LPP	1.26e-03	13	121	2	Orphanet_101960
Disease	hypothyroidism (implicated_via_orthology)	DUOX1 THRA	1.26e-03	13	121	2	DOID:1459 (implicated_via_orthology)
Disease	leukemia (is_implicated_in)	ACSL6 PDGFRA	1.26e-03	13	121	2	DOID:1240 (is_implicated_in)
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	RPS6KA1 HMG20A	1.47e-03	14	121	2	EFO_0006830, EFO_0006896
Disease	MMR-related febrile seizures	SCN1A SCN2A	1.69e-03	15	121	2	EFO_0006519
Disease	Cannabis use	ATP2A1 SDK1	1.93e-03	16	121	2	EFO_0007585
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.93e-03	16	121	2	C0393706
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	2.44e-03	18	121	2	HP_0002373
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	BACH2 LPP	2.44e-03	18	121	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	Intellectual Disability	TCN2 SYNE1 CHD8 BRWD3 TBC1D20 SCN1A RAI1	2.51e-03	447	121	7	C3714756
Disease	autism spectrum disorder (implicated_via_orthology)	PKP4 CHD8 SCN1A SCN2A	3.61e-03	152	121	4	DOID:0060041 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A	3.65e-03	22	121	2	DOID:2030 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MPAPEQASLVEEGQP	PKP4	1	Q99569
PPEIRGDLQQRVVMP	nan	361	A8MVM7
PRDQMLPEPISFEAA	BACH2	181	Q9BYV9
EPVQEPDGETLPSMQ	CHD8	616	Q9HCK8
QEIPMEVFDPSPQGK	CACNB1	16	Q02641
ELFDRIEPDIGMPEP	CHEK1	91	O14757
IEPDIGMPEPDAQRF	CHEK1	96	O14757
GMIPEFVGRLPVVVP	CLPX	491	O76031
PQSPVMQEEIFGPVL	ALDH3A1	326	P30838
LPTQMFPEGATPAEI	AAR2	211	Q9Y312
VMVTFEVEGGPNPPD	ADGRV1	181	Q8WXG9
DGEYVAVEMPPRSPV	CFAP46	1266	Q8IYW2
TIPRRSPFVPQMGDE	BRWD3	931	Q6RI45
LFVENMPGFPDNIRP	APMAP	296	Q9HDC9
NMTRPVDDIPDRPAG	CLCN4	421	P51793
TEPVMQEEIFGPILP	ALDH3B2	246	P48448
MTIEDLPDFPLEGNP	CLIP4	1	Q8N3C7
ALGFNPPDLDIMDRP	ATP2A1	806	O14983
PPQPLEGLEMFAQTI	ATG2A	146	Q2TAZ0
ELLGSPEQRPGMQDP	RAI1	876	Q7Z5J4
DPVVVEDVNLPGMLP	RBM26	316	Q5T8P6
PPVQEMVDELQGPFS	NOMO3	736	P69849
MGQVEENRGPVLPPE	PCOLCE	401	Q15113
PALSEAGVMLPEQPA	RAD21	246	O60216
LIPFVVDEQRMLPPS	QRICH2	266	Q9H0J4
VDEQRMLPPSVPGRD	QRICH2	271	Q9H0J4
EFLNIRIPPGDPMFD	DUOX1	121	Q9NRD9
DPMFDPDQRGDVVLP	DUOX1	131	Q9NRD9
VPDPDVAFVPLGMTD	PDGFRA	121	P16234
GAQIRPAPDEPVQME	REST	641	Q13127
PPVQEMVDELQGPFS	NOMO2	736	Q5JPE7
PFSPDPEVQMLIFVV	OR10V1	16	Q8NGI7
TTFPRPVTVEPMDQL	NONO	216	Q15233
EVLDVRENPNLVMPP	FLII	366	Q13045
MTAAPQPFRVDILPV	FRAS1	2421	Q86XX4
RDMGPPTFPEDVPAL	LZTS1	486	Q9Y250
ENARDGIPMDDIPPL	MUC15	316	Q8N387
PEVPFPEITRMLGNE	HMG20A	126	Q9NP66
VPGFRPPQSVMADTE	ELAPOR1	476	Q6UXG2
SMQVLEGRAEPEPPQ	FER1L4	346	A9Z1Z3
SPAMDVQFPVPNLEV	KATNB1	421	Q9BVA0
PAVEETPMNVRNVPL	GPR50	356	Q13585
IMDVIEVVPEPGQPL	CPSF1	1141	Q10570
PEGEVVPLHQVDIPM	KCNJ11	226	Q14654
TLTVREDQVFPMNPP	MYH8	71	P13535
FMFPEVIVEPIPIGQ	NME5	141	P56597
PPVQEMVDELQGPFS	NOMO1	736	Q15155
MEQVPEAQPLGDLPI	IL27RA	571	Q6UWB1
GMPPDEIEIEPVRQS	LRRC74A	26	Q0VAA2
EPIMPAPGQEETVRI	LPP	541	Q93052
LVEPRVEQMPQASPG	MICALL1	566	Q8N3F8
PIREQFFEIPMPSII	GDPD1	221	Q8N9F7
MDVRLGLPPVPDNAD	TUBGCP6	226	Q96RT7
LLEQDFPGMRIGPEP	EHD4	81	Q9H223
QQTEDVMPRIEPRLP	MFSD6	656	Q6ZSS7
RGIPFPSIEVGPEDM	PLA2G4F	726	Q68DD2
DIVRQIFDEAMPPPL	DZIP3	406	Q86Y13
PPPVQRVMDPGFLDV	GORASP1	296	Q9BQQ3
MDPIPVEQLIPYVEE	MED30	106	Q96HR3
VRSLFQEQEEPEPGM	PNOC	101	Q13519
MGESIPLAAPVPVEQ	KICS2	1	Q96MD2
SLVDPEVDQQPMGPE	PATZ1	671	Q9HBE1
DILVPIVPPQGTMFV	ITPRIPL1	236	Q6GPH6
QFPVTLELMPPGEGA	HERVK_113	281	P62684
VERFMFEGVEIPLVP	DNAH1	1661	Q9P2D7
PERGQPASLEFLPME	ATP13A2	781	Q9NQ11
VIEDALPGQMNPVLP	DNAH6	4076	Q9C0G6
DQARPGPEIMRTIPE	ESPL1	1476	Q14674
RCLPPVPADMVFLVD	COL20A1	171	Q9P218
TEPLGMRIAEFPLNP	DHX35	476	Q9H5Z1
PEVIGPMRPEQFSDE	GAGE6	21	Q13070
PTREVFLEAMNVGPP	CPTP	166	Q5TA50
GRVLDPIAETMNVPP	EFHB	496	Q8N7U6
EYPDGRIIMVLPEDP	ESCO1	661	Q5FWF5
PEVIGPMRPEQFSDE	GAGE5	21	Q13069
QDFPGMRIGPEPTTD	EHD1	81	Q9H4M9
PVEVFVGEAAPAMAP	SDK1	1691	Q7Z5N4
PRDLPQDPVELAMFG	ECSIT	216	Q9BQ95
LPFVPPEEEFIMGVS	ITGB1BP1	101	O14713
NFPPQGTEREMEETP	PCDHB6	771	Q9Y5E3
DILVMPESPGEVPEY	EPHA6	946	Q9UF33
EMPQPRPFRLESLDI	KIF17	996	Q9P2E2
MDSPIQIFRGEPGPT	OPRK1	1	P41145
EPMVDLDGELPFVRP	MEGF6	456	O75095
RVNMPPAVDPAEFFV	MRPS26	41	Q9BYN8
AQERPLPTDEMAPGR	RUSC1	766	Q9BVN2
SEPLPFQAPGQVLME	TRDMT1	171	O14717
IQLMPFFVDITPPGE	SNX29	766	Q8TEQ0
SVNGIPVPPDQLEDM	SYNE1	471	Q8NF91
VIPEGSPTAMEQPVF	TMEM184B	26	Q9Y519
MLEDIASPRPPAEGF	PRR14	156	Q9BWN1
ESPRVPGDAVIMPFR	TANC1	96	Q9C0D5
QQLPIPGPVEEMLAE	STAT5B	301	P51692
REIPPRFLQEMIAIP	TDRD7	751	Q8NHU6
QDFPGMRIGPEPTTD	EHD3	81	Q9NZN3
MEQTVLVPPGPDSFN	SCN1A	1	P35498
QQLPIPGPVEEMLAE	STAT5A	301	P42229
APRVMLEPAAETIPQ	TCN2	311	P20062
IPEVARQFPEPMPVV	BPIFB2	301	Q8N4F0
FLVGIVVPDPEVMPS	ACSL6	596	Q9UKU0
FLPQRGRPEVTTMPL	ANGEL1	581	Q9UNK9
MIVVFGDEPPVFSRP	TSG101	131	Q99816
PEVRDGMELVPQPED	POGLUT3	476	Q7Z4H8
AEAAAVPLQMPPTEI	TEX13D	251	A0A0J9YY54
RMEEGAQQIFKIPPP	UNC80	1661	Q8N2C7
VVEPMPVRGPDVEAY	TMEM9B	71	Q9NQ34
TPRPVIVEPMEQFDD	PSPC1	226	Q8WXF1
MDESPEPLQQGRGPV	SLC26A1	1	Q9H2B4
PEQFDLIVLTMPVPE	RNLS	151	Q5VYX0
RVGPEDAMPRIVEQP	ROBO3	56	Q96MS0
DAMPRIVEQPPDLLV	ROBO3	61	Q96MS0
MEPVPLQDFVRALDP	THEMIS2	1	Q5TEJ8
EGPFPLSMEILEVPE	THEMIS2	256	Q5TEJ8
YGDIPPEMVSVPLED	SCN2A	66	Q99250
VPPLNDDLDIFGPMI	SMAP1	236	Q8IYB5
DDLDIFGPMISNPLP	SMAP1	241	Q8IYB5
QPEVNHVPLEGPMLE	STAB1	1226	Q9NY15
PSDLREYLEGPPMVV	nan	41	Q6ZUG5
PMPGPQEAVVFEDVA	ZNF517	6	Q6ZMY9
MPEGRVPPERNLFSQ	ZNF827	711	Q17R98
NIPIMDTGENPEVPF	ATP6V0A1	76	Q93050
DTGENPEVPFPRDMI	ATP6V0A1	81	Q93050
PEVPFPRDMIDLEAN	ATP6V0A1	86	Q93050
MAEPPRLPLTFEDVA	ZNF786	1	Q8N393
METEEGPPQQPPETR	TSSK1B	351	Q9BXA7
GIPMVGIPLFFDQPD	UGT2B10	386	P36537
GTPQPRPHEDVFIMD	STRN4	376	Q9NRL3
FLPDDIGQSPIVSMP	THRA	191	P10827
SLRRFPPGMPEEQRE	TBC1D20	106	Q96BZ9
MAQPLAFILDVPETP	TMC6	1	Q7Z403
GLPVDIMADVPFPAT	TSPEAR	176	Q8WU66
GSEILEPFLPAVQMP	TARBP1	911	Q13395
VASPPFMDLEQAVLP	WNK1	1976	Q9H4A3
PVFIMPQRPQTEEKP	ZNF382	281	Q96SR6
GPFLEDEEIPVVVPM	UHRF1BP1	1301	Q6BDS2
FQPMPSITIRPPDDQ	UBR5	2746	O95071
PENSLEREEMGPVPA	CX3CL1	256	P78423
IPENPAMEGFPDARR	UNC79	1561	Q9P2D8
AMEGFPDARRPVIPE	UNC79	1566	Q9P2D8
VVLPAIMPGDSFAVP	VPS13D	3076	Q5THJ4
SMELLGPVPPEQQFI	VPS13D	3751	Q5THJ4
PLMELVPLDPENGQT	RPS6KA1	11	Q15418
NVRIEEEQPEEGMPP	SLC8A3	486	P57103
FPILSVEGVRPPMDV	NAPSA	191	O96009