Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH3 DNAH8

5.80e-0518853GO:0008569
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 DNAH3 KIF6 MYO18B DNAH8

1.49e-04118855GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH3 DNAH8

2.26e-0428853GO:0051959
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DNAH3 KIF6 DNAH8

2.26e-0470854GO:0003777
GeneOntologyMolecularFunctiontranscription factor binding

EHMT2 KLF5 CD34 CTDP1 SRF NCOA1 CRTC1 FOXP1 RUNX3 MEF2A SMAD3

3.43e-047538511GO:0008134
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH3 DNAH8

5.21e-0437853GO:0045505
GeneOntologyMolecularFunctionDEAD/H-box RNA helicase binding

DROSHA SMAD3

6.32e-049852GO:0017151
GeneOntologyMolecularFunctionprimary miRNA binding

DROSHA SRF

7.88e-0410852GO:0070878
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

KLF5 CD34 CTDP1 SRF NCOA1 CRTC1 FOXP1 MEF2A SMAD3

8.20e-04582859GO:0140297
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

MTMR7 MTMR14

9.61e-0411852GO:0052629
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

MTMR7 MTMR14

1.58e-0314852GO:0004438
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

MTMR7 MTMR14

1.81e-0315852GO:0052744
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

CD34 CTDP1 SRF NCOA1 FOXP1 MEF2A SMAD3

2.01e-03417857GO:0061629
GeneOntologyMolecularFunctiontranscription corepressor binding

EHMT2 RUNX3 SMAD3

2.04e-0359853GO:0001222
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

MTMR7 MTMR14

2.07e-0316852GO:0106018
GeneOntologyBiologicalProcessstriated muscle cell differentiation

ATG7 KLF5 CTDP1 ADGRB3 CASP1 SRF FOXP1 MYO18B CDH2 MEF2A

4.24e-063918410GO:0051146
GeneOntologyBiologicalProcessmuscle structure development

ANK2 ATG7 KLF5 CTDP1 ADGRB3 CASP1 SRF FOXP1 UNC45A MYO18B CDH2 UTRN MEF2A SMAD3

8.83e-068588414GO:0061061
GeneOntologyBiologicalProcessmuscle cell differentiation

ANK2 ATG7 KLF5 CTDP1 ADGRB3 CASP1 SRF FOXP1 MYO18B CDH2 MEF2A

1.01e-055318411GO:0042692
GeneOntologyBiologicalProcesscardiac muscle cell development

ATG7 CTDP1 SRF FOXP1 MYO18B MEF2A

1.06e-05122846GO:0055013
GeneOntologyBiologicalProcesscardiac cell development

ATG7 CTDP1 SRF FOXP1 MYO18B MEF2A

1.66e-05132846GO:0055006
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

ATG7 CTDP1 SRF FOXP1 MYO18B MEF2A

8.57e-05177846GO:0055007
GeneOntologyBiologicalProcessmuscle cell development

ANK2 ATG7 CTDP1 SRF FOXP1 MYO18B MEF2A

9.03e-05259847GO:0055001
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH3 DNAH8

1.40e-0425853GO:0005858
GeneOntologyCellularComponentaxoneme

DNHD1 DNAH3 RSPH3 ATG7 RP1 DNAH8

2.00e-04207856GO:0005930
GeneOntologyCellularComponentciliary plasm

DNHD1 DNAH3 RSPH3 ATG7 RP1 DNAH8

2.05e-04208856GO:0097014
GeneOntologyCellularComponentmicrotubule associated complex

DNHD1 DNAH3 KIF6 RP1 DNAH8

5.09e-04161855GO:0005875
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH3

7.20e-0410852GO:0036156
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.62e-0512803PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.62e-0512803IPR027970
DomainDynein_HC_stalk

DNHD1 DNAH3 DNAH8

2.66e-0514803IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH3 DNAH8

2.66e-0514803IPR013602
DomainDHC_N2

DNHD1 DNAH3 DNAH8

2.66e-0514803PF08393
DomainMT

DNHD1 DNAH3 DNAH8

2.66e-0514803PF12777
DomainDHC_fam

DNHD1 DNAH3 DNAH8

3.32e-0515803IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH3 DNAH8

3.32e-0515803IPR004273
DomainDynein_heavy

DNHD1 DNAH3 DNAH8

3.32e-0515803PF03028
DomainMADS

SRF MEF2A

2.69e-046802SM00432
DomainMADS_BOX_1

SRF MEF2A

2.69e-046802PS00350
DomainSRF-TF

SRF MEF2A

2.69e-046802PF00319
DomainMADS_BOX_2

SRF MEF2A

2.69e-046802PS50066
DomainTF_MADSbox

SRF MEF2A

3.75e-047802IPR002100
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH8

1.59e-0314802IPR024317
DomainAAA_8

DNAH3 DNAH8

1.59e-0314802PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH8

1.59e-0314802IPR011704
DomainAAA_5

DNAH3 DNAH8

1.59e-0314802PF07728
DomainGTP_binding_domain

GNL1 URGCP

2.96e-0319802IPR006073
DomainBRCT

CTDP1 BARD1

2.96e-0319802PF00533
DomainTyr_Pase_AS

MTMR7 MTMR14 PTPN21

3.79e-0373803IPR016130
DomainBRCT

CTDP1 BARD1

3.96e-0322802SM00292
DomainActinin_actin-bd_CS

SPTB UTRN

4.32e-0323802IPR001589
DomainSpectrin

SPTB UTRN

4.32e-0323802PF00435
DomainACTININ_2

SPTB UTRN

4.32e-0323802PS00020
DomainACTININ_1

SPTB UTRN

4.32e-0323802PS00019
Domain-

CTDP1 BARD1

4.32e-03238023.40.50.10190
DomainBRCT

CTDP1 BARD1

5.51e-0326802PS50172
DomainBRCT_dom

CTDP1 BARD1

6.37e-0328802IPR001357
DomainSpectrin_repeat

SPTB UTRN

6.82e-0329802IPR002017
Domain-

MTMR7 MTMR14 PTPN21

7.23e-03928033.90.190.10
Domain-

SH3GL2 ICA1L

7.29e-03308021.20.1270.60
DomainAH/BAR-dom

SH3GL2 ICA1L

7.29e-0330802IPR027267
DomainSpectrin/alpha-actinin

SPTB UTRN

8.27e-0332802IPR018159
DomainSPEC

SPTB UTRN

8.27e-0332802SM00150
PathwayREACTOME_RUNX3_REGULATES_BCL2L11_BIM_TRANSCRIPTION

RUNX3 SMAD3

1.54e-045562M27825
PathwayWP_ADIPOGENESIS

KLF5 NCOA1 WWTR1 MEF2A SMAD3

1.68e-04131565M39505
PathwayWP_ADIPOGENESIS_GENES

KLF5 NCOA1 WWTR1 MEF2A SMAD3

2.07e-04137565MM15970
PathwayREACTOME_RUNX3_REGULATES_CDKN1A_TRANSCRIPTION

RUNX3 SMAD3

2.30e-046562MM15534
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5

5.21e-10686420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5

5.21e-10686425930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A7 MYO18B SPATA31A5

3.37e-092486532212159
Pubmed

Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.

ANK2 SPTB CDH2

1.21e-06986328692740
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

CD93 ABR ANK2 EHMT2 DROSHA GCDH MYO18B SMAD3

1.65e-0632986817474147
Pubmed

LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation.

WWTR1 CDH2 SMAD3

2.37e-061186336125128
Pubmed

Transforming growth factor Beta2 is required for valve remodeling during heart development.

CD34 VCAN SMAD3

3.16e-061286321780244
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ANK2 MTMR14 EHMT2 DROSHA SPTB MYO18B UTRN AKAP12 SMAD3

4.01e-0649786923414517
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ABR ANK2 EHMT2 N4BP2 SH3GL2 SEC16A ADGRB3 DCHS1 MPDZ CDH2 CEP170B AKAP12

4.42e-06963861228671696
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EHMT2 KLF5 U2SURP NCOA1 FOXP1 SSBP2 MEF2A

4.77e-0626886733640491
Pubmed

G9A promotes tumor cell growth and invasion by silencing CASP1 in non-small-cell lung cancer cells.

EHMT2 CASP1

6.04e-06286228383547
Pubmed

Runx3 Regulates CD8+ T Cell Local Expansion and CD43 Glycosylation in Mice by H1N1 Influenza A Virus Infection.

SPN RUNX3

6.04e-06286238673806
Pubmed

TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism.

WWTR1 SMAD3

6.04e-06286228739802
Pubmed

Activin A promotes hyaluronan production and upregulates versican expression in human granulosa cells†.

VCAN SMAD3

6.04e-06286235403677
Pubmed

CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks.

EHMT2 CNTN5

6.04e-06286230747104
Pubmed

Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.

KLF5 MEF2A

6.04e-06286220086047
Pubmed

FoxP1 Represses MEF2A in Striated Muscle.

FOXP1 MEF2A

6.04e-06286238483114
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 N4BP2 SEC16A ZNF629 MPDZ CRTC1 WWTR1 UNC45A PTPN21 UTRN CEP170B

9.07e-06861861136931259
Pubmed

Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.

EHMT2 RUNX3

1.81e-05386218850007
Pubmed

Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.

SRF MEF2A

1.81e-05386215728583
Pubmed

SRF-FOXO1 and SRF-NCOA1 Fusion Genes Delineate a Distinctive Subset of Well-differentiated Rhabdomyosarcoma.

SRF NCOA1

1.81e-05386232187044
Pubmed

Steroid receptor coactivator-1 interacts with serum response factor and coactivates serum response element-mediated transactivations.

SRF NCOA1

1.81e-0538629786846
Pubmed

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells.

SRF WWTR1

1.81e-05386226885614
Pubmed

TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis.

KLF5 WWTR1

1.81e-05386222045023
Pubmed

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.

SRF SMAD3

1.81e-05386216824956
Pubmed

Biomarkers of Barrett's Esophagus: From the Laboratory to Clinical Practice.

CRTC1 FOXP1

1.81e-05386229713984
Pubmed

Taz/Tead1 Promotes Alternative Macrophage Activation and Kidney Fibrosis via Transcriptional Upregulation of Smad3.

WWTR1 SMAD3

1.81e-05386239108258
Pubmed

Mechanics-driven nuclear localization of YAP can be reversed by N-cadherin ligation in mesenchymal stem cells.

WWTR1 CDH2

1.81e-05386234711824
Pubmed

Dystrophin involvement in peripheral circadian SRF signalling.

SRF UTRN

1.81e-05386234389686
Pubmed

Enrichment of conserved synaptic activity-responsive element in neuronal genes predicts a coordinated response of MEF2, CREB and SRF.

SRF MEF2A

1.81e-05386223382855
Pubmed

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.

CD93 CD34 IL7R

2.17e-05228639324354
Pubmed

Interaction network of human early embryonic transcription factors.

EHMT2 BAZ1A SEC16A NCOA1 FOXP1 SSBP2 CDH2

2.73e-0535186738297188
Pubmed

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

MPDZ WWTR1 SMAD3

3.23e-052586321145499
Pubmed

Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy.

CRTC1 SMAD3

3.61e-05486223362262
Pubmed

The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells.

FOXP1 SMAD3

3.61e-05486230367168
Pubmed

Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.

ATG7 WWTR1

3.61e-05486238744820
Pubmed

TGFβ-TAZ/SRF signalling regulates vascular smooth muscle cell differentiation.

SRF WWTR1

3.61e-05486228342289
Pubmed

Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells.

FOXP1 IL7R

3.61e-05486221532575
Pubmed

Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

CDH2 SMAD3

3.61e-05486225105734
Pubmed

Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.

ANK2 SPTB

3.61e-05486214593108
Pubmed

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.

SRF MEF2A

3.61e-05486212061776
Pubmed

The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP.

NCOA1 SMAD3

3.61e-05486215688032
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

DOCK4 BAZ1A SPATA31A7 U2SURP CTDP1

4.42e-0515686522952844
Pubmed

p300 cooperates with Smad3/4 and Runx3 in TGFbeta1-induced IgA isotype expression.

RUNX3 SMAD3

6.01e-05586214635047
Pubmed

Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.

FNIP2 MEF2A

6.01e-05586237772772
Pubmed

Sec8 modulates TGF-β induced EMT by controlling N-cadherin via regulation of Smad3/4.

CDH2 SMAD3

6.01e-05586227769780
Pubmed

The spectrin-ankyrin skeleton controls CD45 surface display and interleukin-2 production.

SPN SPTB

6.01e-05586212354383
Pubmed

Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice.

ATG7 CASP1

6.01e-05586232400277
Pubmed

Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction.

ATG7 WWTR1

6.01e-05586231416916
Pubmed

Multiple cadherins are expressed in human fibroblasts.

DCHS1 CDH2

6.01e-0558629199196
Pubmed

β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.

SRF SMAD3

6.01e-05586221965288
Pubmed

RUNX3-mediated up-regulation of miR-29b suppresses the proliferation and migration of gastric cancer cells by targeting KDM2A.

RUNX3 SMAD3

6.01e-05586227497248
Pubmed

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.

ATG7 SEC16A

6.01e-05586227203176
Pubmed

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

WWTR1 SMAD3

6.01e-05586218568018
Pubmed

Inhibitors of oxygen sensing prolyl hydroxylases regulate nuclear localization of the transcription factors Smad2 and YAP/TAZ involved in CTGF synthesis.

WWTR1 SMAD3

6.01e-05586227155083
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

EHMT2 N4BP2 SEC16A CRTC1 FOXP1 UNC45A UTRN

8.18e-0541886734709266
Pubmed

BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.

ATRX BARD1

9.01e-05686228976962
Pubmed

Synergistic induction of CTGF by cytochalasin D and TGFβ-1 in primary human renal epithelial cells: Role of transcriptional regulators MKL1, YAP/TAZ and Smad2/3.

WWTR1 SMAD3

9.01e-05686227721022
Pubmed

The Role of SCL Isoforms in Embryonic Hematopoiesis.

SPN CD34

9.01e-05686237047400
Pubmed

Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation.

CD34 IL7R

9.01e-05686212714519
Pubmed

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus.

RUNX3 IL7R

9.01e-05686223109710
Pubmed

Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins.

CD93 SPN

9.01e-05686221768350
Pubmed

Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex.

DCHS1 MPDZ

9.01e-05686219506035
Pubmed

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver.

ATG7 WWTR1

9.01e-05686234088666
Pubmed

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.

MEF2A SMAD3

9.01e-05686211160896
Pubmed

Role of steroid receptor coactivators in glucocorticoid and transforming growth factor beta regulation of plasminogen activator inhibitor gene expression.

NCOA1 SMAD3

9.01e-05686216423881
Pubmed

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

ATRX BAZ1A BARD1

1.16e-043886311555636
Pubmed

Differential expression of individual gamma-protocadherins during mouse brain development.

PCDHGC5 CDH2

1.26e-04786215964765
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH8

1.26e-0478629256245
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

ANK2 CDH2

1.26e-04786215272007
Pubmed

Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

CASP1 IL7R

1.26e-04786222444631
Pubmed

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43).

FNDC1 CDH2

1.26e-04786219723622
Pubmed

Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.

KLF5 CD34

1.26e-04786218617520
Pubmed

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.

VCAN SMAD3

1.68e-04886221041365
Pubmed

Requirement for core 2 O-glycans for optimal resistance to helminth infection.

SPN CD34

1.68e-04886223555902
Pubmed

Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.

KLF5 SMAD3

1.68e-04886219419955
Pubmed

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter.

RUNX3 SMAD3

1.68e-04886210531362
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

KIAA0586 SEC16A MPDZ UTRN CEP170B

1.75e-0420986536779422
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

U2SURP USP32 UNC45A GNL1 AKAP12

1.87e-0421286533462405
Pubmed

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.

CRTC1 FOXP1

2.15e-04986224121790
Pubmed

HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers.

ATG7 CASP1

2.15e-04986229558368
Pubmed

Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.

VCAN CDH2

2.15e-04986229920846
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

ANK2 CDH2

2.15e-04986217884088
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK2 SPTB

2.68e-041086222159418
Pubmed

Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation.

RUNX3 SMAD3

2.68e-041086215138260
Pubmed

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes.

ATG7 CASP1

2.68e-041086231959973
Pubmed

A fibronectin gradient remodels mixed-phase mesoderm.

WWTR1 CDH2

2.68e-041086239028807
Pubmed

DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse.

VCAN DCHS1

2.68e-041086235200715
Pubmed

Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.

SH3GL2 MPDZ

2.68e-041086211978849
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DNAH3 AKNA NCOA1 ICA1L AKAP12

2.90e-0423386537704626
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CNNM4 ABR ATRX ATG7 SPTB SRF BARD1 FOXP1 UTRN ICA1L MEF2A CEP170B

2.96e-041489861228611215
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

SEC16A GCDH UNC45A UTRN JPT2

3.01e-0423586528378594
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LDLRAP1 UBE4A ANK2 ATRX EHMT2 DROSHA SPTB USP32 ADGRB3 REV3L UTRN

3.25e-041285861135914814
Pubmed

Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches.

CD34 VCAN

3.28e-041186222510689
Pubmed

Mechanical feedback defines organizing centers to drive digit emergence.

CDH2 SMAD3

3.28e-041186235413235
Pubmed

Dchs1-Fat4 regulation of osteogenic differentiation in mouse.

DCHS1 WWTR1

3.28e-041186231358536
Pubmed

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation.

CDH2 IL7R

3.28e-041186219429912
Pubmed

Versican facilitates chondrocyte differentiation and regulates joint morphogenesis.

VCAN SMAD3

3.28e-041186220404343
Pubmed

Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.

CDH2 SMAD3

3.28e-041186222498737
Pubmed

Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2.

SRF NCOA1

3.28e-041186210847592
InteractionTEAD1 interactions

EHMT2 SRF NCOA1 MPDZ FOXP1 WWTR1 SSBP2 MEF2A

5.93e-07176828int:TEAD1
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

9.64e-058862chr9q12
CytobandEnsembl 112 genes in cytogenetic band chr6p21

KIF6 EHMT2 SRF MICA DNAH8 GNL1

3.77e-04503866chr6p21
Cytoband9p13.1

SPATA31A1 SPATA31A3

9.32e-04248629p13.1
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

SRF MEF2A

8.38e-0555321086
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR7 MTMR14

8.64e-0415532903
GeneFamilyDyneins, axonemal

DNAH3 DNAH8

1.11e-0317532536
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK4 ATRX BAZ1A U2SURP BARD1 NCOA1 WWTR1 SSBP2 REV3L CDH2 MEF2A CREB5 IL7R SMAD3

5.37e-078568414M4500
CoexpressionAtlasalpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3

N4BP2 FOXP1 SSBP2 REV3L DNAH8 UTRN AKAP12 IL7R

2.61e-05302848GSM399362_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

RSPH3 ANK2 ADGRB3 DCHS1 AKNA NCOA1 GCDH WWTR1 SSBP2 RUNX3 CDH2 CREB5

2.99e-057328412Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100

VCAN SSBP2 REV3L

3.90e-0517843gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#1

CNNM4 RSPH3 ATG7 KLF5 CEP170B

5.55e-05103845Facebase_RNAseq_e10.5_Mandibular Arch_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4

RSPH3 KLF5 ADGRB3 NCOA1 SSBP2 RUNX3 CREB5

5.60e-05247847Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#2

RSPH3 ANK2 BAZ1A ADGRB3 AKNA NCOA1 GCDH WWTR1 SSBP2 RUNX3 CREB5

5.62e-056598411Facebase_RNAseq_e10.5_Olfactory Pit_2500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

RSPH3 ANK2 BAZ1A ADGRB3 AKNA NCOA1 GCDH WWTR1 SSBP2 RUNX3 CREB5

8.26e-056888411Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlasgamma delta T cells, Tgd.vg2-.Sp, TCRd+ Vg2- CD44-, Spleen, avg-3

SPN AKNA FOXP1 RUNX3 DNAH8 UTRN IL7R SMAD3

1.35e-04382848GSM476684_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2

RSPH3 ANK2 BAZ1A ADGRB3 AKNA NCOA1 GCDH WWTR1 SSBP2 RUNX3 CREB5

1.70e-047478411Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlasgamma delta T cells, Tgd.vg2-.Sp.TCRbko, TCRd+ Vg2- CD44-, Spleen, avg-3

SPN SRF AKNA RUNX3 DNAH8 UTRN IL7R SMAD3

2.01e-04405848GSM605796_500
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 ADGRB3 WWTR1 UTRN MEF2A

9.34e-0819286727ff3621e177e7932dd44dd6baa81551ea75a874
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX FOXP1 UTRN MEF2A AKAP12 IL7R

1.55e-061848661154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 CD93 CD34 WWTR1 CREB5 IL7R

1.81e-061898665d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

1.98e-0619286628eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.04e-061938662e72309607902dabe3218888b22a77fe941f3570
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK4 CD93 DCHS1 WWTR1 RP1 AKAP12

2.04e-06193866c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.10e-06194866b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

VCAN ADGRB3 NCOA1 SSBP2 REV3L SMAD3

2.16e-06195866ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

LDLRAP1 ATRX N4BP2 CRTC1 FOXP1 IL7R

2.16e-06195866d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.16e-0619586677e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.23e-061968668ad8efb631164b46f0c082572270188e5ead20bf
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 ADGRB3 WWTR1 UTRN

2.23e-06196866ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.23e-061968669606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.23e-06196866145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 WWTR1 UTRN

2.29e-06197866c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 WWTR1 UTRN

2.29e-061978662844dbcd0a673ed81c99920aa45858651a00736d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-0619886607701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-06198866b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-0619886631ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-06198866953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 ADGRB3 UTRN MEF2A

2.36e-061988668689090bce9ab6e8f122426a404037e572c6713b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-06198866fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-061988660a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3 UTRN

2.36e-061988668e45551224fbb30c0658ad47dd98335ecf165437
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CD93 ATRX MPDZ FOXP1 UTRN IL7R

2.50e-06200866dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 CNTN5 ADGRB3

1.47e-051608650d4880f85565d8c540c94a8f8109147b3029279a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32A KLF5 SPTB DCHS1 UTRN

1.52e-05161865dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CASP1 AKNA RUNX3 IL7R

2.15e-051738656397b3fa72e2621a9a0f27f49446de2d3a30e420
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 UTRN CEP170B AKAP12 IL7R

2.33e-0517686529cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 SPTB MYO18B CDH2 CREB5

2.33e-051768659df7a124ebafb0087da0cda133a394275d7bed81
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 UTRN CEP170B AKAP12 IL7R

2.33e-0517686501774a86d7d92f31a056b753f9844f923038003e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 DCHS1

2.53e-051798658f9e538c822940785130297712b75131812a4603
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 CD34 FOXP1 UTRN AKAP12

2.74e-05182865ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 CD34 FOXP1 UTRN AKAP12

2.74e-0518286597a805783a1f2b055c21307db250e3688674eff3
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 C12orf71 ADGRB3 UTRN

2.81e-051838653c4153479fc4ab2d073d92cee120480015555914
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 CD34 WWTR1 CREB5 IL7R

2.81e-05183865e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A KLF5 SPTB UTRN AKAP12

2.89e-05184865e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 CD93 MPDZ REV3L UTRN

2.89e-0518486567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VCAN ADGRB3 CREB5 AKAP12 SMAD3

2.96e-05185865e58a009aaf342be019a909747b1895d5987d4daf
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

2.96e-05185865d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD93 VCAN CNTN5 DNAH8 CREB5

3.04e-0518686523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 CD34 FOXP1 UTRN AKAP12

3.04e-05186865ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 CD34 FOXP1 UTRN AKAP12

3.04e-0518686565e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 CD34 FOXP1 UTRN AKAP12

3.04e-05186865e4f1259725160719e5fd13d76e5a707efed70013
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 CD93 CD34 BTBD18 WWTR1

3.12e-051878653548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 WWTR1

3.12e-0518786535c382c0aabd46906113e5db30ea24bb8e658899
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 CD93 CD34 BTBD18 WWTR1

3.12e-05187865f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 CD93 CD34 BTBD18 WWTR1

3.12e-0518786581754e965848b718be20ee97ce072ce426938a69
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

LDLRAP1 N4BP2 CRTC1 FOXP1 IL7R

3.20e-05188865b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

3.20e-051888656c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A KLF5 SPTB UTRN AKAP12

3.20e-05188865c300accbac71a3bc075fe985543d8a8ead82531b
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

ANK2 CD34 VCAN CREB5 AKAP12

3.20e-05188865706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FNDC1 ANK2 CD34 VCAN CREB5

3.20e-05188865409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 ADGRB3 WWTR1 AKAP12

3.28e-05189865c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCellCOPD-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

DOCK4 CD93 VCAN SSBP2 SMAD3

3.28e-051898656294691231c7d38707323cf31578a107d3b2c622
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 UTRN

3.28e-0518986512b6f1c3bf526b90e112374bf937701f645c5780
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 UTRN

3.36e-05190865bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FNIP2 ANK2 MYO18B CDH2 CREB5

3.36e-0519086593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 SPTB MYO18B CDH2 CREB5

3.36e-05190865918ad5037881212008f9f69d5df5da91fd01422c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 UTRN

3.45e-05191865b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD34 FOXP1 SSBP2 UTRN AKAP12

3.45e-05191865054fa0493b00149313c243d39cf39a264044f074
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

3.54e-0519286530cefa0990ba1f379f350bfbf994a78db145075e
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

3.54e-051928650e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

BAZ1A KLF5 CREB5 AKAP12 SMAD3

3.54e-051928658b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCelldroplet-Kidney-nan-3m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A KLF5 SPTB UTRN AKAP12

3.54e-051928658b625c22dda23c99654c82c529a1233e99e71b54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 ABR CD34 ADGRB3 UTRN

3.54e-0519286556b021c297a21dff357531f21e2464f85186106d
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 CD93 CD34 WWTR1 IL7R

3.62e-05193865aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 CD93 CD34 WWTR1 IL7R

3.62e-05193865c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 CD93 CD34 WWTR1 IL7R

3.62e-05193865e1d546165dcc2392f540162206852c4717d7306f
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

VCAN REV3L CREB5 AKAP12 SMAD3

3.62e-051938657426c291bac59e539c427bcaae18abc7d397d44e
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

3.62e-05193865025836c5c5a711e477c326559e618e47cae42d11
ToppCellT_cell|World / shred by cell class for nasal brushing

SPN KLF5 AKNA RUNX3 IL7R

3.62e-0519386507530bbeffd5951880ed6ea50a962c102b05ccc2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 UTRN

3.62e-051938656a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 UTRN

3.62e-051938650b328f725f6feba263783eaca60c142e80df90f3
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 CD34 VCAN CREB5 AKAP12

3.71e-051948657b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCellCTRL-Myeloid-Monocyte_Macrophage|Myeloid / Disease state, Lineage and Cell class

FNIP2 DOCK4 CD93 VCAN RUNX3

3.71e-0519486573459ee062ae1f1a3bb9719dc0b89aae10600e22
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 UTRN

3.71e-05194865f76808666fb875fc787751cbfd924d9be20a8192
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX N4BP2 FOXP1 AKAP12 IL7R

3.71e-051948658ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellCTRL-Myeloid-Monocyte_Macrophage|CTRL / Disease state, Lineage and Cell class

FNIP2 DOCK4 CD93 VCAN RUNX3

3.71e-05194865927480f56cccd3940b689f3c40ee132fe3e63745
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 UTRN

3.71e-05194865f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 UTRN

3.71e-05194865a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FNIP2 STK32A DCHS1 HHLA1

3.76e-0597864f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 WWTR1 AKAP12

3.81e-05195865a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD34 FOXP1 SSBP2 UTRN AKAP12

3.81e-05195865dc84a910b6f6eb9994cd683aa4fd813a82198e5f
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD93 CD34 DCHS1 AKAP12 IL7R

3.81e-05195865667a2ed4b865e9a37674b3d154bb5bf2188b3ebf
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

VCAN ADGRB3 REV3L AKAP12 SMAD3

3.81e-051958656a02ebbeb3199447ddce64d92d8809436e040eba
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX SEC16A NCOA1 REV3L CDH2

3.81e-051958653e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

DOCK4 CD93 CD34 UTRN MEF2A

3.81e-0519586550a193475db1bb1e05b8590225a553688c372c14
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX SEC16A NCOA1 REV3L CDH2

3.81e-051958657796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

GFY SPN AKNA RUNX3 UTRN

3.81e-051958659990440bda7fac5d00ef80444fab07459be625e1
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

FNDC1 CD34 VCAN CREB5 AKAP12

3.90e-051968657e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UBE4A BAZ1A AKNA UTRN IL7R

3.90e-05196865ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CD93 CD34 MPDZ WWTR1 AKAP12

3.90e-0519686514dd6956ef420b660be0baf52a66960e57d75d16
ToppCellILEUM-non-inflamed-(9)_Enteric_neurons|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 ADGRB3 DCHS1 CDH2 CREB5

3.90e-05196865998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GFY SPN AKNA RUNX3 UTRN

3.90e-05196865418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 CD34 ADGRB3 UTRN

3.90e-05196865ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3

3.90e-051968658f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GFY SPN AKNA RUNX3 UTRN

3.90e-05196865581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CD93 ABR CD34 ADGRB3

3.90e-0519686548b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 ABR CD34 ADGRB3 UTRN

3.90e-05196865b8f89a50114932c08fc5daac4b549adfe9df8e66
DrugCID11987713

ABR SPN CD34 CASP1 FOXP1 JPT2 IL7R SMAD3

3.88e-07190818CID011987713
DrugPractolol [6673-35-4]; Down 200; 15uM; PC3; HT_HG-U133A

METTL25B ABR U2SURP SH3GL2 UNC45A PTPN21 UTRN

7.06e-061998174603_DN
DrugGly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A

DNAH3 CD34 CASP1 NCOA1 UNC45A PTPN21 RUNX3

7.06e-061998176560_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

CNNM4 BAZ1A KLF5 U2SURP WWTR1 SMAD3

6.20e-051918161063_DN
Druggeldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A

CNNM4 DNAH3 SPN MRM1 KIAA0586 SMAD3

6.57e-051938161653_DN
Drugrapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A

CNNM4 U2SURP SH3GL2 UNC45A PTPN21 IL7R

6.76e-051948165932_DN
DrugMoxalactam disodium salt [64953-12-4]; Down 200; 7uM; PC3; HT_HG-U133A

METTL25B MRM1 U2SURP CTDP1 SSBP2 CDH2

6.76e-051948164648_DN
Drug17-AAG; Down 200; 1uM; SKMEL5; HG-U133A

ABR BAZ1A CRTC1 RUNX3 JPT2 SMAD3

6.96e-05195816505_DN
Drug17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A

DNAH3 METTL25B KLF5 KIAA0586 WWTR1 SMAD3

6.96e-051958166973_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A

SPN VCAN SPTB SRF PTPN21 UTRN

6.96e-051958164433_DN
DrugMorantel tartrate [26155-31-7]; Up 200; 10.8uM; HL60; HT_HG-U133A

SPN CD34 SRF GCDH UTRN CEP170B

7.16e-051968161840_UP
DrugPregnenolone [145-13-1]; Down 200; 12.6uM; PC3; HT_HG-U133A

U2SURP SSBP2 RUNX3 UTRN MEF2A IL7R

7.16e-051968164218_DN
DrugKawain [500-64-1]; Down 200; 17.4uM; PC3; HT_HG-U133A

SPN ZNF629 NCOA1 RUNX3 URGCP SMAD3

7.16e-051968167369_DN
DrugCP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A

DNAH3 VCAN SPTB CRTC1 HHLA1 SMAD3

7.16e-051968167491_DN
DrugHydrocortisone base [50-23-7]; Down 200; 11uM; PC3; HT_HG-U133A

ATRX MRM1 SRF WWTR1 SSBP2 IL7R

7.16e-051968166684_DN
DrugBetazole hydrochloride; Down 200; 27uM; PC3; HT_HG-U133A

CNNM4 METTL25B SPN VCAN SRF URGCP

7.16e-051968166344_DN
DrugThiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

MRM1 CRTC1 GCDH PTPN21 AKAP12 SMAD3

7.16e-051968167479_UP
DrugThyroxine (L) [51-48-9]; Down 200; 5.2uM; HL60; HT_HG-U133A

LDLRAP1 DNAH3 ZNF629 UNC45A JPT2 MEF2A

7.16e-051968161312_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

ABR SPN VCAN SRF UNC45A URGCP

7.36e-051978161732_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A

DOCK4 CD34 CASP1 CRTC1 PTPN21 UTRN

7.36e-051978165605_DN
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A

LDLRAP1 SPN MRM1 VCAN U2SURP CTDP1

7.36e-051978164547_DN
DrugXylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A

SPN CASP1 CRTC1 PTPN21 URGCP CREB5

7.36e-051978164066_DN
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A

METTL25B MRM1 VCAN CRTC1 PTPN21 RUNX3

7.36e-051978164189_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; PC3; HT_HG-U133A

ZNF629 MPDZ GCDH RUNX3 UTRN IL7R

7.36e-051978167293_DN
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; PC3; HT_HG-U133A

SPN U2SURP ZNF629 MPDZ URGCP IL7R

7.57e-051988167251_DN
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A

CNNM4 METTL25B MRM1 KIAA0586 NCOA1 GCDH

7.57e-051988165533_DN
DrugTrimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A

CTDP1 SRF DCHS1 CRTC1 PTPN21 RUNX3

7.57e-051988165479_UP
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A

METTL25B SPN MRM1 GCDH MEF2A SMAD3

7.57e-051988163112_DN
Drug2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A

SPN KLF5 VCAN MPDZ UTRN URGCP

7.57e-051988162700_DN
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

ABR ATG7 SRF MPDZ GCDH UTRN

7.57e-051988161479_DN
DrugICI 182,780; Up 200; 0.01uM; MCF7; HG-U133A

DNAH3 SPN CTDP1 WWTR1 MEF2A SMAD3

7.57e-05198816310_UP
DrugTorsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

VCAN CNTN5 CASP1 NCOA1 CRTC1 PTPN21

7.78e-051998165476_UP
DrugAcemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A

CNNM4 METTL25B SPN MRM1 VCAN PTPN21

7.78e-051998166361_DN
DrugHydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A

MRM1 U2SURP GCDH WWTR1 UNC45A REV3L

8.00e-052008165284_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA

U2SURP CTDP1 NCOA1 WWTR1 PTPN21 AKAP12

8.00e-05200816995_DN
DrugAdiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; HL60; HT_HG-U133A

SPN MRM1 ZNF629 CRTC1 UNC45A CEP170B

8.00e-052008161872_DN
DrugA25618

PCDHGC5 EHMT2 SRF NCOA1 FOXP1 MYO18B RUNX3 MEF2A CREB5 AKAP12 SMAD3

9.38e-057778111CID000005562
Drugbronopol

VCAN JPT2

1.24e-045812CID000002450
Diseaseurate measurement, bone density

FNDC1 KIF6 WDR64 EHMT2 CD34 SEC16A ADGRB3 CRTC1 DNAH8 UTRN AKAP12

1.15e-066198211EFO_0003923, EFO_0004531
DiseaseCarcinoma, Ovarian Epithelial

MTMR14 EHMT2 USP32

7.96e-0530823C4721610
DiseaseColorectal Carcinoma

CD93 DNAH3 ANK2 KLF5 DCHS1 C2CD6 DNAH8 AKAP12 SMAD3

1.45e-04702829C0009402
Diseasegastroesophageal reflux disease

VCAN CRTC1 FOXP1 MON1A

1.84e-04101824EFO_0003948
Diseaseunderweight body mass index status

ANK2 ADGRB3

2.71e-049822EFO_0005936
DiseaseUterine Cancer

BARD1 SMAD3

3.38e-0410822C0153567
Diseasethiamine measurement

N4BP2 CRTC1

3.38e-0410822EFO_0010540
Diseasecentral corneal thickness, intraocular pressure measurement

FOXP1 SMAD3

4.13e-0411822EFO_0004695, EFO_0005213
DiseaseNasal Cavity Polyp

NCOA1 FOXP1 IL7R

4.89e-0455823EFO_1000391
Diseasethyroid gland carcinoma (is_marker_for)

CD93 CD34

4.94e-0412822DOID:3963 (is_marker_for)
Diseasereticulocyte measurement

BAZ1A CNTN5 SPTB U2SURP USP32 FOXP1 GCDH MICA RUNX3 GNL1

6.70e-0410538210EFO_0010700
DiseaseAdenocarcinoma Of Esophagus

CRTC1 FOXP1

6.79e-0414822C0279628
DiseaseHiatus hernia

CRTC1 FOXP1

6.79e-0414822HP_0002036
Diseaseallergic disease

KLF5 MICA RUNX3 IL7R SMAD3

7.75e-04258825MONDO_0005271
Diseasetestosterone measurement

DOCK4 UBE4A ANK2 NICN1 ZNF629 AKNA NCOA1 FOXP1 PTPN21 UTRN JPT2

7.89e-0412758211EFO_0004908
Diseasekeratoconus

KLF5 CRTC1 SMAD3

8.34e-0466823MONDO_0015486
Diseasesquamous cell carcinoma

SEC16A FOXP1 MICA

8.72e-0467823EFO_0000707
Diseaseidiopathic scoliosis (implicated_via_orthology)

KIF6 RUNX3

8.93e-0416822DOID:0060250 (implicated_via_orthology)
Diseaseglutarylcarnitine (C5-DC) measurement

FNIP2 GCDH

1.01e-0317822EFO_0800030
Diseaserhinitis

IL7R SMAD3

1.01e-0317822EFO_0008521
Diseaseesophageal adenocarcinoma, digestive system disease, Barrett's esophagus

CRTC1 FOXP1

1.13e-0318822EFO_0000280, EFO_0000405, EFO_0000478
Diseaseesophageal adenocarcinoma

CRTC1 FOXP1

1.13e-0318822EFO_0000478
Diseaseintellectual disability (implicated_via_orthology)

ANK2 ATRX MEF2A

1.21e-0375823DOID:1059 (implicated_via_orthology)
Diseaseasthma, allergic disease

RUNX3 IL7R SMAD3

1.40e-0379823MONDO_0004979, MONDO_0005271
Diseasecolorectal cancer

KLF5 VCAN CNTN5 ADGRB3 MICA UNC45A SMAD3

1.47e-03604827MONDO_0005575
Diseaseleptin measurement

CD93 SPTB DNAH8

1.51e-0381823EFO_0005000
Diseasediaphragmatic hernia

CRTC1 FOXP1

1.55e-0321822EFO_0008561
Diseasecongestive heart failure (is_marker_for)

CASP1 SRF FOXP1

1.56e-0382823DOID:6000 (is_marker_for)
Diseasebalding measurement

KLF5 MPDZ CRTC1 FOXP1 REV3L RUNX3 AKAP12 SMAD3

1.61e-03792828EFO_0007825
Diseasecorneal resistance factor

CD34 NICN1 VCAN FOXP1 WWTR1 SMAD3

1.62e-03451826EFO_0010067
Diseasepsoriatic arthritis

MICA REV3L RUNX3

1.85e-0387823EFO_0003778
Diseasetrans fatty acid measurement, trans/trans-18:2 fatty acid measurement

CNTN5 MYO18B

2.02e-0324822EFO_0006821, EFO_0006826
Diseaseankylosing spondylitis

MICA RUNX3 IL7R

2.11e-0391823EFO_0003898
DiseaseFEV/FEC ratio

ABR CNTN5 U2SURP KIAA0586 CRTC1 FOXP1 WWTR1 RUNX3 IL7R SMAD3

2.12e-0312288210EFO_0004713
Diseaseatopic asthma

EHMT2 MICA IL7R SMAD3

2.33e-03199824EFO_0010638
Diseaseunipolar depression, depressive symptom measurement

FNIP2 CNTN5

2.37e-0326822EFO_0003761, EFO_0007006
Diseasewhite matter integrity, age at assessment

VCAN ICA1L

2.37e-0326822EFO_0004641, EFO_0008007
Diseaseoptic disc size measurement

KIF6 VCAN FOXP1 CDH2

2.59e-03205824EFO_0004832
Diseaseupper respiratory tract disorder

IL7R SMAD3

2.75e-0328822MONDO_0004867
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

CDH2 MEF2A

2.75e-0328822DOID:1094 (implicated_via_orthology)
DiseaseBarrett's esophagus

CRTC1 FOXP1

2.75e-0328822EFO_0000280
DiseasePancreatic Neoplasm

ATRX KLF5 FOXP1

2.76e-03100823C0030297

Protein segments in the cluster

PeptideGeneStartEntry
QENMSSRTDSPIPPF

nan

26

A8MT66
DESPTMSPQLSARSQ

ABR

51

Q12979
TGDMNAPPGSRESQT

CTDP1

326

Q9Y5B0
SNMSDEFISLSPGTP

BARD1

381

Q99728
SLVNMSTPDPDANGL

VCAN

2176

P13611
FRDIPNTSSMENPAP

ADGRB3

1451

O60242
MGAGSSTEQRSPEQP

AKAP12

1

Q02952
ESRAMENQYSPTPGT

CD93

636

Q9NPY3
DVPGRADTSQPSARM

EHMT2

571

Q96KQ7
EPTEETFNPMSQLAR

C1orf232

41

A0A0U1RR37
LSGPFMDPTQDQRST

DNHD1

956

Q96M86
VPPGSLNSRDFDQNM

CEP170B

1396

Q9Y4F5
EPLMSESTSNIDQGP

BAZ1A

861

Q9NRL2
TGDPSTPSRMIRTNE

CNTN5

756

O94779
PPMVNVTRSEASEGN

MICA

206

Q29983
TNMDEVPRPQALSGS

LDLRAP1

231

Q5SW96
PSSMDSNSSPEEVQF

ANK2

2696

Q01484
TDNMLSDQTPTPTRF

CREB5

51

Q02930
PEGQDPQTLTMLRAS

DCHS1

1761

Q96JQ0
STVPFRNPDENSRGM

SPN

241

P16150
MKSFPSRSPSQGDED

MTMR7

586

Q9Y216
SDNFFRMGSSPLEVP

MTMR14

521

Q8NCE2
NRMASNIFGPTEEPQ

JPT2

41

Q9H910
MEPPQETNRPFSTLD

C2CD6

1

Q53TS8
LNDNSPSFATPEREM

PCDHGC5

126

Q9Y5F6
FDQSMARSEKSPLPQ

DNAH8

3716

Q96JB1
NESDSSPGRSPMQAV

FOXP1

616

Q9H334
PEEGQRMRLSSAPSQ

KIF6

516

Q6ZMV9
QTDSAMEPTGPTQER

GNL1

341

P36915
FRTPEINNSSGEMDP

IL7R

226

P16871
TRMPGFQTPSEFLEN

METTL25B

101

Q96FB5
PRQEMGRSPVDSLSS

MEF2A

446

Q02078
SSNPSITGSDVMRPD

PTPN21

416

Q16825
TPSDGQSMERAESPT

MON1A

116

Q86VX9
PSGTQPFSSNEQEMS

BTBD18

396

B2RXH4
PFSSNEQEMSPTRTE

BTBD18

401

B2RXH4
ETSSPPRLAMNQNTD

ATRX

31

P46100
SSSDDRMNEPPTSLG

ATG7

606

O95352
SFEQPDGRAQMPTTE

CASP1

376

P29466
SESSDEVFNMQPSPS

DOCK4

1661

Q8N1I0
TFPGSRPMSPEQQLD

DNAH3

196

Q8TD57
EPNSGSDPSSMETRA

GCDH

181

Q92947
SRPEFPETPNTDLMQ

GFY

161

I3L273
MDLPFQTPFQSSGLD

CRTC1

76

Q6UUV9
LGSREDSPMSPSDTQ

FNDC1

546

Q4ZHG4
STPVDMPSRGQNEDR

FNIP2

221

Q9P278
RATPMEFQDSSAPPA

AKNA

256

Q7Z591
MDSFGQPRPEDNQSV

ICA1L

1

Q8NDH6
PSPNMFTINNETGDI

CDH2

316

P19022
MSLDNNGTATPELPT

CD34

31

P28906
NDFSPVEPNSSSLME

MTBP

536

Q96DY7
EPRTSEEPGSITNSM

RP1

1441

P56715
NSPTALSTPGRMDEA

RUNX3

396

Q13761
RSSPPTTAGTEEAMN

HHLA1

351

C9JL84
MSQPSAPDFVQRGFD

UTRN

866

P46939
INIMSRLGQDDPTPS

DROSHA

946

Q9NRR4
SLSNQPGTPRDDGEM

SSBP2

326

P81877
QDPQEPSARSEGLSM

MRM1

321

Q6IN84
LSPQDDTNSGMSIPR

NCOA1

371

Q15788
GETPQNLSRDMKSFP

SPATA31A7

676

Q8IWB4
GLPDPSRVSSEVQQM

NICN1

166

Q9BSH3
MGANTSRKPPVFDEN

STK32A

1

Q8WU08
PRSDPTTDQRMSATG

SRF

226

P11831
FEPPQSDSDGQRRSM

U2SURP

231

O15042
AQQDFQLSSGSPPEM

C12orf71

156

A8MTZ7
LASRMENSPQFPIDG

CNNM4

721

Q6P4Q7
GETPQNLSRDMKSFP

SPATA31A3

676

Q5VYP0
DMPTRTAPGESAFRN

TSGA13

246

Q96PP4
SQPPRGMGSFREDSV

URGCP

241

Q8TCY9
RGSQPPDMASALTDR

RSPH3

136

Q86UC2
RQDENTPSVDISMGP

MPDZ

911

O75970
VSRNNDMLTPTPDSS

REV3L

1841

O60673
GETPQNLSRDMKSFP

SPATA31A1

676

Q5TZJ5
PEEAMSGQQSRNPSS

SEC16A

761

O15027
AMFSELSNPESLPAQ

SEC16A

1076

O15027
GETPQNLSRDMKSFP

SPATA31A5

676

Q5VU36
SQPSMTVDGFTDPSN

SMAD3

251

P84022
MSLEFPTGDSTQPNG

SH3GL2

261

Q99962
MTSATEFENVGNQPP

SPTB

1

P11277
GSRSPDPEQMTSING

MYO18B

111

Q8IUG5
DQTDPFNRSPLTMDQ

UBE4A

1026

Q14139
MSLERSSQDPSVPQN

ZNF629

61

Q9UEG4
DPPGELAVTANSRMS

UNC45A

356

Q9H3U1
NEMFTLTTNGDLPRP

USP32

1021

Q8NFA0
APSQQQVSPGDMDRT

KIAA0586

1456

Q9BVV6
ERNFSQPTDNPTMDL

WDR64

631

B1ANS9
PDMRSITNNSSDPFL

WWTR1

286

Q9GZV5
SSEPGSPDRQAEMLQ

KLF5

306

Q13887
SSEFINPDSSNMTPI

N4BP2

176

Q86UW6