Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	intermediate filament organization	KRT4 KRT76 PLEC DSP	4.11e-06	75	30	4	GO:0045109
GeneOntologyBiologicalProcess	keratinocyte differentiation	KRT4 KRT76 PLEC UBN1 DSP	7.25e-06	189	30	5	GO:0030216
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	KRT4 KRT76 PLEC DSP	1.24e-05	99	30	4	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	KRT4 KRT76 PLEC DSP	1.29e-05	100	30	4	GO:0045103
GeneOntologyBiologicalProcess	epithelial cell differentiation	KRT4 FOXP4 KRT76 SALL1 PLEC UBN1 DSP MAP3K1	2.48e-05	870	30	8	GO:0030855
GeneOntologyBiologicalProcess	positive regulation of protein ubiquitination	DNAJA3 MARCHF7 HUWE1 UBQLN1	3.02e-05	124	30	4	GO:0031398
GeneOntologyBiologicalProcess	epidermal cell differentiation	KRT4 KRT76 PLEC UBN1 DSP	5.13e-05	284	30	5	GO:0009913
GeneOntologyBiologicalProcess	protein polyubiquitination	MARCHF7 ANAPC16 HUWE1 MAP3K1 UBR4	5.58e-05	289	30	5	GO:0000209
GeneOntologyBiologicalProcess	positive regulation of protein modification by small protein conjugation or removal	DNAJA3 MARCHF7 HUWE1 UBQLN1	6.36e-05	150	30	4	GO:1903322
GeneOntologyBiologicalProcess	positive regulation of post-translational protein modification	DNAJA3 MARCHF7 HUWE1 UBQLN1	6.52e-05	151	30	4	GO:1901875
GeneOntologyBiologicalProcess	protein ubiquitination	DNAJA3 MARCHF7 ANAPC16 HUWE1 UBQLN1 MAP3K1 UBR4	1.30e-04	811	30	7	GO:0016567
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNRC6A	1.84e-04	14	30	2	GO:0060213
GeneOntologyBiologicalProcess	skin development	KRT4 KRT76 PLEC UBN1 DSP	1.85e-04	373	30	5	GO:0043588
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	DNAJA3 MARCHF7 ANAPC16 HUWE1 UBQLN1 MAP3K1 UBR4	2.36e-04	893	30	7	GO:0032446
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNRC6A	2.42e-04	16	30	2	GO:0060211
GeneOntologyBiologicalProcess	regulation of protein ubiquitination	DNAJA3 MARCHF7 HUWE1 UBQLN1	3.08e-04	226	30	4	GO:0031396
GeneOntologyBiologicalProcess	epidermis development	KRT4 KRT76 PLEC UBN1 DSP	4.90e-04	461	30	5	GO:0008544
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	DNAJA3 MARCHF7 ANAPC16 HUWE1 UBQLN1 MAP3K1 UBR4	4.96e-04	1009	30	7	GO:0070647
GeneOntologyBiologicalProcess	regulation of protein modification by small protein conjugation or removal	DNAJA3 MARCHF7 HUWE1 UBQLN1	6.10e-04	271	30	4	GO:1903320
GeneOntologyBiologicalProcess	regulation of post-translational protein modification	DNAJA3 MARCHF7 HUWE1 UBQLN1	6.62e-04	277	30	4	GO:1901873
GeneOntologyBiologicalProcess	post-translational protein modification	DNAJA3 MARCHF7 ANAPC16 HUWE1 UBQLN1 MAP3K1 UBR4	7.21e-04	1074	30	7	GO:0043687
GeneOntologyBiologicalProcess	epithelium development	KRT4 FOXP4 KRT76 SALL1 PLEC UBN1 DSP MAP3K1	9.22e-04	1469	30	8	GO:0060429
GeneOntologyBiologicalProcess	proteolysis involved in protein catabolic process	MARCHF7 ANAPC16 HUWE1 UBQLN1 MAP3K1 UBR4	9.65e-04	812	30	6	GO:0051603
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNRC6A	1.05e-03	33	30	2	GO:0000289
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	DNAJA3 KRT4 KRT76 PLEC DSP MAP3K1 RP1L1	2.82e-04	899	31	7	GO:0099513
GeneOntologyCellularComponent	intermediate filament	KRT4 KRT76 PLEC DSP	3.38e-04	227	31	4	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT4 KRT76 PLEC DSP	5.90e-04	263	31	4	GO:0045111
Domain	UBA-like	TNRC6B HUWE1 UBQLN1 TNRC6A	3.21e-06	64	30	4	IPR009060
Domain	Ago_hook	TNRC6B TNRC6A	7.48e-06	3	30	2	PF10427
Domain	TNRC6-PABC_bdg	TNRC6B TNRC6A	7.48e-06	3	30	2	PF16608
Domain	TNRC6_PABC-bd	TNRC6B TNRC6A	7.48e-06	3	30	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6B TNRC6A	7.48e-06	3	30	2	IPR019486
Domain	-	PLEC DSP	3.73e-05	6	30	2	3.90.1290.10
Domain	Plectin_repeat	PLEC DSP	5.21e-05	7	30	2	IPR001101
Domain	Plectin	PLEC DSP	5.21e-05	7	30	2	PF00681
Domain	PLEC	PLEC DSP	5.21e-05	7	30	2	SM00250
Domain	GrpE_coiled_coil	KRT4 KRT76	1.63e-04	12	30	2	IPR013805
Domain	Keratin_II	KRT4 KRT76	7.91e-04	26	30	2	IPR003054
Domain	Spectrin_repeat	PLEC DSP	9.86e-04	29	30	2	IPR002017
Domain	UBA	HUWE1 UBQLN1	1.06e-03	30	30	2	SM00165
Domain	Spectrin/alpha-actinin	PLEC DSP	1.20e-03	32	30	2	IPR018159
Domain	SPEC	PLEC DSP	1.20e-03	32	30	2	SM00150
Domain	UBA	HUWE1 UBQLN1	1.52e-03	36	30	2	PF00627
Domain	ARM-type_fold	HUWE1 UBQLN1 MAP3K1 UBR4	2.01e-03	339	30	4	IPR016024
Domain	UBA	HUWE1 UBQLN1	2.26e-03	44	30	2	IPR015940
Domain	Keratin_I	KRT4 KRT76	2.26e-03	44	30	2	IPR002957
Domain	UBA	HUWE1 UBQLN1	2.58e-03	47	30	2	PS50030
Domain	Intermediate_filament_CS	KRT4 KRT76	4.58e-03	63	30	2	IPR018039
Domain	Prefoldin	KRT4 DSP	5.95e-03	72	30	2	IPR009053
Domain	IF	KRT4 KRT76	5.95e-03	72	30	2	PS00226
Domain	Filament	KRT4 KRT76	6.11e-03	73	30	2	PF00038
Domain	IF	KRT4 KRT76	6.60e-03	76	30	2	IPR001664
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX	TNRC6B ANAPC16 TNRC6A	3.38e-05	41	22	3	M29748
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6A	3.47e-05	6	22	2	MM15083
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6A	4.86e-05	7	22	2	M46421
Pathway	REACTOME_GENE_SILENCING_BY_RNA	TNRC6B NUP58 TNRC6A	5.80e-05	49	22	3	MM14837
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	TNRC6B TNRC6A	8.31e-05	9	22	2	M27810
Pathway	REACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION	TNRC6B TNRC6A	8.31e-05	9	22	2	M46436
Pathway	REACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS	TNRC6B TNRC6A	1.04e-04	10	22	2	M48013
Pathway	REACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION	TNRC6B TNRC6A	1.79e-04	13	22	2	M46434
Pathway	REACTOME_CELLULAR_SENESCENCE	TNRC6B ANAPC16 UBN1 TNRC6A	2.22e-04	197	22	4	M27188
Pathway	REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6A	3.12e-04	17	22	2	M27788
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT4 KRT76 DSP	3.21e-04	87	22	3	MM15351
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS	TNRC6B TNRC6A	3.91e-04	19	22	2	M48238
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	TNRC6B PLEC TNRC6A	7.65e-04	117	22	3	M19248
Pathway	REACTOME_TGFBR3_EXPRESSION	TNRC6B TNRC6A	8.57e-04	28	22	2	M48253
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT4 KRT76 DSP	1.02e-03	129	22	3	M27649
Pathway	REACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	TNRC6B TNRC6A	1.12e-03	32	22	2	M48012
Pathway	REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6A	1.12e-03	32	22	2	M27900
Pathway	REACTOME_GENE_SILENCING_BY_RNA	TNRC6B NUP58 TNRC6A	1.26e-03	139	22	3	M715
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4	TNRC6B TNRC6A	1.27e-03	34	22	2	M46422
Pathway	REACTOME_ONCOGENE_INDUCED_SENESCENCE	TNRC6B TNRC6A	1.34e-03	35	22	2	M27190
Pathway	REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX	TNRC6B TNRC6A	1.50e-03	37	22	2	M29790
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	PLEC DSP	1.50e-03	37	22	2	MM14488
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	PLEC DSP	1.58e-03	38	22	2	M495
Pathway	REACTOME_KERATINIZATION	KRT4 KRT76 DSP	1.66e-03	153	22	3	MM15343
Pathway	REACTOME_CELL_CELL_COMMUNICATION	TNRC6B PLEC TNRC6A	1.72e-03	155	22	3	M522
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	NUP58 TNRC6A	1.84e-03	41	22	2	MM15200
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	TNRC6B TNRC6A	2.41e-03	47	22	2	M29777
Pathway	REACTOME_SIGNALING_BY_TGFBR3	TNRC6B TNRC6A	2.62e-03	49	22	2	M48250
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	PLEC DSP	2.62e-03	49	22	2	MM15448
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	PLEC DSP	2.94e-03	52	22	2	M2341
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	AFF1 KRT76 ITPRID2 SALL1 PLEC UBQLN1 UBN1 MAP3K1 UBR4	9.84e-11	430	31	9	35044719
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TNRC6B SALL1 HUWE1 PLEC RFX1 DSP UBR4 TNRC6A	2.52e-09	418	31	8	34709266
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	NUP58 HUWE1 PLEC UBQLN1 DSP UBR4	1.89e-07	288	31	6	23383273
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	DNAJA3 ZNF362 SALL1 HUWE1 TAF5 RFX1 DSP	6.65e-07	583	31	7	29844126
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ITPRID2 NUP58 SALL1 HUWE1 UBN1 DSP TNRC6A	7.04e-07	588	31	7	38580884
Pubmed	Functional proteomics mapping of a human signaling pathway.	DNAJA3 AFF1 HUWE1 PLEC UBQLN1 RFX1 UBR4	7.29e-07	591	31	7	15231748
Pubmed	Role of GW182 protein in the cell.	TNRC6B TNRC6A	7.69e-07	2	31	2	29791863
Pubmed	Epithelial structural proteins of the skin and oral cavity: function in health and disease.	KRT4 DSP	7.69e-07	2	31	2	11132762
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	KRT4 HUWE1 DSP UBR4	9.48e-07	84	31	4	29563501
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM131 ITPRID2 HUWE1 UBR4	1.09e-06	87	31	4	12465718
Pubmed	MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.	DNAJA3 PRR18 TNRC6A	1.46e-06	25	31	3	32528060
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6B TNRC6A	2.31e-06	3	31	2	34108231
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6B TNRC6A	2.31e-06	3	31	2	16880270
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6B TNRC6A	2.31e-06	3	31	2	31670606
Pubmed	Human transcription factor protein interaction networks.	TNRC6B FOXP4 SALL1 TAF5 R3HDM1 UBN1 RFX1 UBR4 TNRC6A	2.89e-06	1429	31	9	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	AFF1 ITPRID2 HUWE1 PLEC UBN1 RFX1 DSP	4.34e-06	774	31	7	15302935
Pubmed	TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.	HUWE1 UBR4	4.61e-06	4	31	2	37324936
Pubmed	Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.	TNRC6B TNRC6A	4.61e-06	4	31	2	21063388
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	DNAJA3 TNRC6B UBQLN1 UBR4 TNRC6A	8.02e-06	313	31	5	16196087
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TMEM131 NUP58 HUWE1 PLEC UBQLN1 R3HDM1 DSP UBR4	1.25e-05	1285	31	8	35914814
Pubmed	The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.	TNRC6B TNRC6A	1.61e-05	7	31	2	19383768
Pubmed	Functional dissection of the human TNRC6 (GW182-related) family of proteins.	TNRC6B TNRC6A	1.61e-05	7	31	2	19470757
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	FOXP4 HUWE1 PLEC UBR4	2.04e-05	182	31	4	31067453
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TNRC6B UBN1 DSP TNRC6A	2.13e-05	184	31	4	32908313
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	DNAJA3 TNRC6B FOXP4 PLEC DSP TNRC6A	2.15e-05	655	31	6	35819319
Pubmed	Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases.	PLEC DSP	2.76e-05	9	31	2	15500642
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	PLEC DSP	2.76e-05	9	31	2	12482924
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	HUWE1 UBQLN1 UBR4	2.82e-05	66	31	3	24811749
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TNRC6B TMEM131 ANAPC16 HUWE1 R3HDM1 TNRC6A	4.03e-05	733	31	6	34672954
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	PLEC DSP	4.21e-05	11	31	2	12802069
Pubmed	Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.	HUWE1 UBQLN1 UBR4	4.84e-05	79	31	3	27325702
Pubmed	PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins.	HUWE1 UBQLN1	5.05e-05	12	31	2	31904842
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DNAJA3 TNRC6B HUWE1 PLEC DSP UBR4 TNRC6A	5.24e-05	1139	31	7	36417873
Pubmed	A human MAP kinase interactome.	ITPRID2 NUP58 PLEC DSP TNRC6A	6.57e-05	486	31	5	20936779
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	TNRC6B TNRC6A	6.95e-05	14	31	2	19716330
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	HUWE1 UBR4	6.95e-05	14	31	2	27626314
Pubmed	MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis.	DSP MAP3K1	6.95e-05	14	31	2	14627958
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	TNRC6B ITPRID2 PLEC DSP TNRC6A	7.10e-05	494	31	5	26831064
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	TNRC6B TNRC6A	8.02e-05	15	31	2	21981923
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TNRC6B TMEM131 R3HDM1 TNRC6A	8.56e-05	263	31	4	34702444
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	DNAJA3 KRT4 KRT76 UBR4	8.95e-05	266	31	4	19380743
Pubmed	Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.	ITPRID2 PLEC DSP	9.21e-05	98	31	3	26561776
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DNAJA3 TNRC6B TMEM131 PLEC DSP TNRC6A	9.32e-05	853	31	6	28718761
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXP4 SALL1 HUWE1 RFX1 DSP UBR4	9.56e-05	857	31	6	25609649
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	ITPRID2 PLEC R3HDM1 TNRC6A	1.00e-04	274	31	4	34244482
Pubmed	Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.	ANAPC16 UBR4	1.04e-04	17	31	2	29033132
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	DNAJA3 KRT76 PLEC DSP	1.15e-04	284	31	4	29459677
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	AFF1 ANAPC16 HUWE1	1.16e-04	106	31	3	31024071
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TNRC6B HUWE1 TAF5 RFX1 DSP	1.16e-04	549	31	5	38280479
Pubmed	Autoregulation of the 26S proteasome by in situ ubiquitination.	HUWE1 UBR4	1.30e-04	19	31	2	24743594
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	DNAJA3 KRT4 KRT76 PLEC DSP	1.32e-04	564	31	5	21565611
Pubmed	EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.	TNRC6B PLEC	1.60e-04	21	31	2	33029523
Pubmed	Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.	TNRC6B TNRC6A	1.76e-04	22	31	2	22187428
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	MUC19 TNRC6B ITPRID2	1.80e-04	123	31	3	26912792
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	DNAJA3 TNRC6B MARCHF7 UBQLN1 R3HDM1	1.87e-04	608	31	5	16713569
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	FOXP4 ZNF362 UBQLN1	1.89e-04	125	31	3	32891193
Pubmed	Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.	TNRC6B TNRC6A	1.92e-04	23	31	2	28811219
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DNAJA3 TNRC6B KRT4 HUWE1 PLEC DSP UBR4	2.02e-04	1415	31	7	28515276
Pubmed	Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.	KRT76 SALL1 UBN1 DSP	2.09e-04	332	31	4	30595499
Pubmed	Tagging genes with cassette-exchange sites.	TMEM131 PLEC TAF5 UBR4	2.17e-04	335	31	4	15741177
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	PLEC DSP	2.28e-04	25	31	2	30309841
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	DNAJA3 TNRC6B TMEM131 ZNF362 ITPRID2 R3HDM1	2.30e-04	1007	31	6	34597346
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	ANAPC16 HUWE1 DSP UBR4 TNRC6A	2.36e-04	639	31	5	23443559
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	KRT76 HUWE1 PLEC UBR4	2.40e-04	344	31	4	30333137
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	TNRC6B HUWE1 PLEC DSP UBR4	2.50e-04	647	31	5	26618866
Pubmed	Proteomic analysis of the NOS2 interactome in human airway epithelial cells.	DNAJA3 HUWE1 PLEC	2.53e-04	138	31	3	23438482
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	DNAJA3 TNRC6B HUWE1 DSP UBR4	2.68e-04	657	31	5	36180527
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DNAJA3 ZNF362 ITPRID2 HUWE1 DSP TNRC6A	2.86e-04	1049	31	6	27880917
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	FOXP4 RFX1	2.86e-04	28	31	2	29365100
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	HUWE1 UBR4	2.86e-04	28	31	2	35474067
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	AFF1 PLEC MAP3K1	2.99e-04	146	31	3	20686565
Pubmed	The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.	DNAJA3 UBN1	3.08e-04	29	31	2	12438443
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	TNRC6B R3HDM1 TNRC6A	3.36e-04	152	31	3	38360978
Pubmed	Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes.	UBQLN1 DSP	3.75e-04	32	31	2	19815544
Pubmed	The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle.	HUWE1 UBR4	3.75e-04	32	31	2	36278411
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DNAJA3 TNRC6B FOXP4 ZNF362 TAF5 TNRC6A	3.98e-04	1116	31	6	31753913
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	HUWE1 UBR4	3.99e-04	33	31	2	33567268
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	DNAJA3 SALL1 HUWE1 UBR4	4.08e-04	396	31	4	26687479
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TNRC6B TMEM131 PLEC R3HDM1 TNRC6A	4.18e-04	724	31	5	36232890
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	HUWE1 UBQLN1 DSP UBR4	4.20e-04	399	31	4	37536630
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	TNRC6B HUWE1 TNRC6A	4.35e-04	166	31	3	35687106
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MUC19 HUWE1 DSP SCN3A UBR4	4.51e-04	736	31	5	29676528
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	DNAJA3 TNRC6B TNRC6A	4.58e-04	169	31	3	31462741
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	HUWE1 UBR4 TNRC6A	4.66e-04	170	31	3	23314748
Pubmed	Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.	HUWE1 UBR4	4.75e-04	36	31	2	35379950
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	NUP58 R3HDM1 TNRC6A	5.51e-04	180	31	3	35198878
Pubmed	The von Hippel-Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases.	DNAJA3 TNRC6B	5.87e-04	40	31	2	34004371
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DNAJA3 TNRC6B R3HDM1 TNRC6A	6.38e-04	446	31	4	24255178
Pubmed	Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2.	HUWE1 UBQLN1	6.47e-04	42	31	2	27578003
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MUC19 HUWE1 PLEC DSP UBR4	6.84e-04	807	31	5	30575818
Pubmed	Global landscape of HIV-human protein complexes.	AFF1 HUWE1 DSP UBR4	6.99e-04	457	31	4	22190034
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DNAJA3 TNRC6B MARCHF7 HUWE1 DSP UBR4	7.46e-04	1257	31	6	37317656
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ITPRID2 PLEC DSP	7.70e-04	202	31	3	33005030
Pubmed	Discovery and refinement of loci associated with lipid levels.	AFF1 PLEC MAP3K1	8.73e-04	211	31	3	24097068
Interaction	PHF21A interactions	TNRC6B NUP58 SALL1 HUWE1 PLEC DSP UBR4 TNRC6A	2.74e-08	343	30	8	int:PHF21A
Interaction	SMAD9 interactions	DNAJA3 AFF1 HUWE1 PLEC UBQLN1 RFX1	8.86e-08	153	30	6	int:SMAD9
Interaction	TFDP3 interactions	MARCHF7 ITPRID2 PLEC UBR4	2.27e-07	36	30	4	int:TFDP3
Interaction	CYLD interactions	MUC19 TNRC6B KRT4 FOXP4 HUWE1 PLEC UBQLN1 DSP UBR4 TNRC6A	2.86e-07	868	30	10	int:CYLD
Interaction	KRT19 interactions	TNRC6B KRT4 KRT76 PLEC DSP TNRC6A	3.19e-06	282	30	6	int:KRT19
Interaction	TRIM65 interactions	TNRC6B MARCHF7 HUWE1 TNRC6A	5.83e-06	80	30	4	int:TRIM65
Interaction	UBE2D2 interactions	MARCHF7 HUWE1 PLEC UBQLN1 MAP3K1 UBR4	6.35e-06	318	30	6	int:UBE2D2
Interaction	DDX6 interactions	TNRC6B AFF1 TMEM131 HUWE1 PLEC DSP TNRC6A	7.16e-06	503	30	7	int:DDX6
Interaction	BRCA1 interactions	DNAJA3 TNRC6B ANAPC16 ITPRID2 HUWE1 PLEC DSP MAP3K1 UBR4 TNRC6A	7.72e-06	1249	30	10	int:BRCA1
Interaction	KRT28 interactions	KRT4 KRT76 NUP58	1.18e-05	30	30	3	int:KRT28
Interaction	CNOT3 interactions	TNRC6B TMEM131 HUWE1 DSP TNRC6A	1.26e-05	207	30	5	int:CNOT3
Interaction	SPATA1 interactions	NUP58 RFX1 UBR4	1.30e-05	31	30	3	int:SPATA1
Interaction	KRT18 interactions	KRT4 KRT76 HUWE1 PLEC DSP TNRC6A	3.03e-05	419	30	6	int:KRT18
Interaction	TRIM37 interactions	TNRC6B ITPRID2 HUWE1 PLEC UBN1 DSP TNRC6A	3.07e-05	630	30	7	int:TRIM37
Interaction	KRT8 interactions	TNRC6B KRT76 PLEC DSP UBR4 TNRC6A	4.03e-05	441	30	6	int:KRT8
Interaction	SYNE3 interactions	TNRC6B TMEM131 ITPRID2 NUP58 PLEC TNRC6A	4.19e-05	444	30	6	int:SYNE3
Interaction	CIC interactions	DNAJA3 ZNF362 SALL1 HUWE1 TAF5 RFX1 DSP	4.67e-05	673	30	7	int:CIC
Interaction	TNRC6C interactions	TNRC6B NUP58 DSP TNRC6A	5.02e-05	138	30	4	int:TNRC6C
Interaction	KDM1A interactions	DNAJA3 TNRC6B HUWE1 PLEC RFX1 DSP UBR4 TNRC6A	5.12e-05	941	30	8	int:KDM1A
Interaction	RCOR1 interactions	TNRC6B SALL1 HUWE1 PLEC DSP UBR4	7.58e-05	494	30	6	int:RCOR1
Interaction	CNOT6 interactions	TNRC6B TMEM131 TNRC6A	7.82e-05	56	30	3	int:CNOT6
Interaction	RTL8A interactions	HUWE1 UBQLN1	1.17e-04	11	30	2	int:RTL8A
Interaction	PAQR9 interactions	HUWE1 UBQLN1	1.17e-04	11	30	2	int:PAQR9
Interaction	ZUP1 interactions	KRT4 HUWE1 DSP UBR4	1.23e-04	174	30	4	int:ZUP1
Interaction	YAP1 interactions	TNRC6B KRT76 HUWE1 PLEC UBQLN1 TAF5 RFX1 DSP	1.48e-04	1095	30	8	int:YAP1
Interaction	PRKD1 interactions	ITPRID2 PLEC DSP UBR4	1.53e-04	184	30	4	int:PRKD1
Interaction	FAM184A interactions	TNRC6B MAP3K1 TNRC6A	1.66e-04	72	30	3	int:FAM184A
Interaction	KRT36 interactions	KRT4 KRT76 MAP3K1	1.80e-04	74	30	3	int:KRT36
Interaction	CNOT8 interactions	TNRC6B TMEM131 TNRC6A	1.80e-04	74	30	3	int:CNOT8
Interaction	KRT14 interactions	KRT4 KRT76 PLEC DSP	1.80e-04	192	30	4	int:KRT14
Interaction	RNF208 interactions	KRT4 KRT76 UBQLN1	1.87e-04	75	30	3	int:RNF208
Interaction	CRK interactions	DNAJA3 KRT4 KRT76 HUWE1 PLEC	1.98e-04	370	30	5	int:CRK
Interaction	PHIP interactions	TNRC6B FOXP4 TAF5 TNRC6A	1.99e-04	197	30	4	int:PHIP
Interaction	KRT16 interactions	KRT4 KRT76 PLEC DSP	1.99e-04	197	30	4	int:KRT16
Interaction	FEV interactions	FOXP4 SALL1 TAF5 RFX1	2.23e-04	203	30	4	int:FEV
Interaction	PRPH interactions	KRT76 PLEC DSP TNRC6A	2.27e-04	204	30	4	int:PRPH
Interaction	RBMS1 interactions	TNRC6B UBQLN1 R3HDM1 TNRC6A	2.40e-04	207	30	4	int:RBMS1
Interaction	PRRC2A interactions	TNRC6B HUWE1 UBQLN1 R3HDM1 TNRC6A	2.50e-04	389	30	5	int:PRRC2A
Interaction	UBXN1 interactions	MARCHF7 HUWE1 UBQLN1 UBR4	2.68e-04	213	30	4	int:UBXN1
Interaction	SCG2 interactions	PLEC UBQLN1	2.87e-04	17	30	2	int:SCG2
Interaction	UNK interactions	TNRC6B HUWE1 UBQLN1 R3HDM1 TNRC6A	3.12e-04	408	30	5	int:UNK
Interaction	SERPINI2 interactions	NUP58 UBQLN1	3.23e-04	18	30	2	int:SERPINI2
Interaction	RAD23A interactions	HUWE1 UBQLN1 MAP3K1 UBR4	3.25e-04	224	30	4	int:RAD23A
Interaction	CNOT6L interactions	TNRC6B TMEM131 TNRC6A	3.53e-04	93	30	3	int:CNOT6L
Interaction	KRT33B interactions	KRT4 KRT76 NUP58	3.53e-04	93	30	3	int:KRT33B
Interaction	AGR2 interactions	MUC19 NUP58 HUWE1 PLEC UBQLN1 DSP UBR4	3.58e-04	934	30	7	int:AGR2
Interaction	CNOT9 interactions	TNRC6B TMEM131 SALL1 TNRC6A	3.65e-04	231	30	4	int:CNOT9
Interaction	SOX17 interactions	FOXP4 SALL1 DSP	3.76e-04	95	30	3	int:SOX17
Interaction	SRGN interactions	UBQLN1 UBR4	4.00e-04	20	30	2	int:SRGN
Interaction	ATXN3 interactions	DNAJA3 HUWE1 UBQLN1 DSP MAP3K1	4.36e-04	439	30	5	int:ATXN3
Interaction	LATS1 interactions	TNRC6B KRT4 PLEC R3HDM1 TNRC6A	4.40e-04	440	30	5	int:LATS1
Interaction	EYA4 interactions	TNRC6B PLEC R3HDM1 TNRC6A	4.42e-04	243	30	4	int:EYA4
Interaction	DNAJB2 interactions	MARCHF7 UBQLN1 MAP3K1	4.63e-04	102	30	3	int:DNAJB2
Interaction	RNF113A interactions	DNAJA3 TNRC6B FOXP4 PLEC DSP TNRC6A	4.71e-04	692	30	6	int:RNF113A
Interaction	ELP2 interactions	AFF1 HUWE1 UBR4	5.04e-04	105	30	3	int:ELP2
Interaction	USP7 interactions	DNAJA3 MARCHF7 SALL1 HUWE1 PLEC UBN1 DSP SCN3A	5.11e-04	1313	30	8	int:USP7
Interaction	NINL interactions	TNRC6B TMEM131 HUWE1 DSP TNRC6A	5.29e-04	458	30	5	int:NINL
Interaction	DRC3 interactions	MUC19 MARCHF7	5.32e-04	23	30	2	int:DRC3
Interaction	ANKHD1-EIF4EBP3 interactions	TNRC6B HUWE1 TNRC6A	5.47e-04	108	30	3	int:ANKHD1-EIF4EBP3
Interaction	CNOT11 interactions	TNRC6B TMEM131 TNRC6A	6.08e-04	112	30	3	int:CNOT11
Interaction	PIH1D1 interactions	TNRC6B KRT4 HUWE1 PLEC DSP UBR4	6.29e-04	731	30	6	int:PIH1D1
Interaction	GABRD interactions	TMEM131 UBQLN1	6.29e-04	25	30	2	int:GABRD
Interaction	NUP155 interactions	TNRC6B TMEM131 NUP58 HUWE1 TNRC6A	6.36e-04	477	30	5	int:NUP155
Interaction	DUSP4 interactions	ITPRID2 PLEC DSP	7.08e-04	118	30	3	int:DUSP4
Interaction	KIZ interactions	TNRC6B TNRC6A	7.35e-04	27	30	2	int:KIZ
Interaction	GABRA3 interactions	TMEM131 UBQLN1	7.90e-04	28	30	2	int:GABRA3
Interaction	TTC3 interactions	HUWE1 DSP UBR4	8.18e-04	124	30	3	int:TTC3
Interaction	SOX2 interactions	FOXP4 ZNF362 ITPRID2 SALL1 RFX1 DSP UBR4 TNRC6A	8.67e-04	1422	30	8	int:SOX2
Interaction	MAPRE1 interactions	MARCHF7 TMEM131 ITPRID2 NUP58 PLEC	8.90e-04	514	30	5	int:MAPRE1
Interaction	UBE2D1 interactions	MARCHF7 HUWE1 UBQLN1 MAP3K1	9.02e-04	294	30	4	int:UBE2D1
Interaction	R3HDM2 interactions	TNRC6B R3HDM1 TNRC6A	9.17e-04	129	30	3	int:R3HDM2
Interaction	SOCS6 interactions	DNAJA3 PLEC UBQLN1	9.37e-04	130	30	3	int:SOCS6
Interaction	ITGB2 interactions	HUWE1 PLEC UBR4	9.80e-04	132	30	3	int:ITGB2
Interaction	HDAC1 interactions	TNRC6B AFF1 SALL1 PLEC RFX1 UBR4 TNRC6A	9.94e-04	1108	30	7	int:HDAC1
Interaction	PSMD14 interactions	HUWE1 PLEC UBQLN1 DSP UBR4	9.95e-04	527	30	5	int:PSMD14
Interaction	FLNB interactions	UBQLN1 DSP MAP3K1 UBR4	1.02e-03	304	30	4	int:FLNB
Interaction	SERINC5 interactions	HUWE1 UBR4	1.03e-03	32	30	2	int:SERINC5
Interaction	VIM interactions	TNRC6B KRT76 PLEC DSP UBR4 TNRC6A	1.03e-03	804	30	6	int:VIM
Interaction	GRB2 interactions	DNAJA3 KRT4 HUWE1 PLEC MAP3K1 UBR4	1.05e-03	806	30	6	int:GRB2
Interaction	ANAPC5 interactions	ANAPC16 HUWE1 TNRC6A	1.11e-03	138	30	3	int:ANAPC5
Interaction	YTHDF2 interactions	TNRC6B HUWE1 R3HDM1 TNRC6A	1.12e-03	312	30	4	int:YTHDF2
Interaction	CNOT7 interactions	TNRC6B TMEM131 TNRC6A	1.16e-03	140	30	3	int:CNOT7
Interaction	COL17A1 interactions	PLEC DSP	1.17e-03	34	30	2	int:COL17A1
Interaction	CNOT10 interactions	TNRC6B TMEM131 TNRC6A	1.19e-03	141	30	3	int:CNOT10
Interaction	SMG7 interactions	TNRC6B SALL1 R3HDM1 TNRC6A	1.22e-03	319	30	4	int:SMG7
Interaction	UCHL5 interactions	HUWE1 UBQLN1 DSP MAP3K1	1.22e-03	319	30	4	int:UCHL5
Interaction	KRT26 interactions	KRT4 KRT76	1.24e-03	35	30	2	int:KRT26
Interaction	KRT25 interactions	KRT4 KRT76	1.24e-03	35	30	2	int:KRT25
Interaction	GLDC interactions	ITPRID2 PLEC R3HDM1 TNRC6A	1.25e-03	321	30	4	int:GLDC
Interaction	DAZL interactions	TNRC6B R3HDM1 TNRC6A	1.28e-03	145	30	3	int:DAZL
Interaction	CPEB1 interactions	TNRC6B R3HDM1 TNRC6A	1.31e-03	146	30	3	int:CPEB1
Cytoband	12q13.13	KRT4 KRT76	9.49e-04	67	31	2	12q13.13
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	MARCHF7 SCN3A	3.35e-03	127	31	2	chr2q24
GeneFamily	EF-hand domain containing\|Plakins	PLEC DSP	5.11e-05	8	25	2	939
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6B TNRC6A	5.40e-04	25	25	2	775
GeneFamily	Keratins, type II	KRT4 KRT76	6.31e-04	27	25	2	609
Coexpression	GSE21033_1H_VS_12H_POLYIC_STIM_DC_DN	TNRC6B HUWE1 RP1L1 TNRC6A	2.26e-05	141	31	4	M7720
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	AFF1 TMEM131 R3HDM1 TNRC6A	3.44e-05	157	31	4	M7733
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP	KRT4 NUP58 UBN1 PPP1R2C	8.15e-05	196	31	4	M5252
Coexpression	GSE3982_MAC_VS_BCELL_DN	TMEM131 MAP3K1 SCN3A UBR4	8.31e-05	197	31	4	M5495
Coexpression	GSE40273_XBP1_KO_VS_WT_TREG_DN	TNRC6B TMEM131 ZNF362 PLEC	8.64e-05	199	31	4	M9124
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP	TMEM131 ANAPC16 ZNF362 R3HDM1	8.81e-05	200	31	4	M9646
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP	ITPRID2 SCN3A UBR4 TNRC6A	8.81e-05	200	31	4	M4033
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	KLHL29 KRT4 FOXP4 NUP58 SALL1 HUWE1 DSP SCN3A	8.79e-06	806	29	8	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500	KLHL29 KRT4 SALL1 HUWE1 DSP SCN3A	1.56e-05	407	29	6	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF1 KRT4 HUWE1 UBN1 DSP	1.73e-07	185	31	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	droplet-Bladder-Unstain\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT4 ITPRID2 PLEC DSP	1.00e-05	196	31	4	f240056e63aca02f25ea29bc9d34eedcf0f1c811
ToppCell	droplet-Bladder-Unstain-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT4 ITPRID2 PLEC DSP	1.00e-05	196	31	4	0d040ae2ce8a0e1a59145a9b9eaa979239c477ff
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNRC6B KRT4 KRT76 DSP	1.02e-05	197	31	4	e621d4f9d4ba5e3ef17d2b477e5e14ea0251147e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT4 KRT76 PLEC DSP	1.02e-05	197	31	4	d968d7d5608b175bb567ea3a315bf473ec3be459
Drug	NSC37726	ITPRID2 PLEC	5.03e-06	3	30	2	CID000003302
Drug	U-1373	ITPRID2 PLEC	5.03e-06	3	30	2	CID000102133
Drug	AsF5	ITPRID2 TAF5	2.51e-05	6	30	2	CID000082223
Drug	3-buten-1-ol	KRT4 SALL1	3.51e-05	7	30	2	CID000069389
Disease	cortical thickness	KLHL29 TNRC6B AFF1 TMEM131 PLEC UBN1 MAP3K1 TNRC6A	1.12e-05	1113	30	8	EFO_0004840
Disease	cortical surface area measurement	KLHL29 TNRC6B AFF1 MARCHF7 TAF5 MAP3K1 RP1L1 TNRC6A	4.35e-05	1345	30	8	EFO_0010736
Disease	Tinnitus	TNRC6B KRT4 TMEM131	3.11e-04	130	30	3	HP_0000360
Disease	body surface area	KLHL29 PLEC UBN1 ACAN TNRC6A	4.39e-04	643	30	5	EFO_0022196
Disease	neuroimaging measurement	DNAJA3 TNRC6B AFF1 PLEC MAP3K1 TNRC6A	6.27e-04	1069	30	6	EFO_0004346

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSSSAGGVSGSSVTG	ANAPC16	6	Q96DE5
TGSESSGSVGSSTGS	R3HDM1	406	Q15032
SGMGSSSGSIQTSGG	KRT76	596	Q01546
SGSSVATSGQQSGGT	PPP1R2C	21	O14990
SVVSGSTSTGGISGG	KRT4	461	P19013
VSGSTGVSAGSITAS	MUC19	1781	Q7Z5P9
SVEATTSAGSGNTAG	MUC19	1906	Q7Z5P9
RTGTTGQSGAESGTT	MUC19	2316	Q7Z5P9
SGTTGTLSGGSSTTR	MUC19	2546	Q7Z5P9
SVIGTRTTGTSSGGS	MUC19	2771	Q7Z5P9
RTTGTSSGGSGATRS	MUC19	2776	Q7Z5P9
TTISSVGGTGTTGQS	MUC19	3006	Q7Z5P9
GVTGTTGSSAGVTGT	MUC19	3761	Q7Z5P9
GVTGTTTVSAGVTGT	MUC19	3801	Q7Z5P9
TGQSVGVTGTTRSSG	MUC19	3906	Q7Z5P9
TGTVGSSAVVTGTTG	MUC19	4171	Q7Z5P9
TETTGSSTGVTGATG	MUC19	4351	Q7Z5P9
SGGVTGTSGISAEVT	MUC19	4816	Q7Z5P9
SAGVTGTIGSSAGVT	MUC19	5236	Q7Z5P9
SAGVTGTIGSSAGVT	MUC19	5616	Q7Z5P9
GTTTVSAGVTGTTGL	MUC19	5711	Q7Z5P9
GATGQSVGVTGTTRS	MUC19	5841	Q7Z5P9
SVGVTGTTRSSGGVT	MUC19	5846	Q7Z5P9
TKTTTSLGGSGTTGA	MUC19	7106	Q7Z5P9
ETTTSLGGSGTTGAE	MUC19	7271	Q7Z5P9
RGTGTTGSGMNTGTT	MUC19	7896	Q7Z5P9
TGSKTGYTVTGSGTT	MUC19	8026	Q7Z5P9
GTTASGTGREVTTGA	FOXP4	36	Q8IVH2
ATSGAGSTTSGVVSG	HUWE1	1846	Q7Z6Z7
STGSGKSSGTVSSVS	ITPRID2	156	P28290
VSGTTSGSGESSGIT	ACAN	1816	P16112
GVGTSSSMGSGVSDD	DSP	2566	P15924
SATTGGSTSDSAQGG	MARCHF7	456	Q9H992
GTVNGVTLTSSGGST	DNAJA3	436	Q96EY1
GGGSSSTGTSAITTS	SALL1	161	Q9NSC2
SAGTGTTAAGTSSGA	PRR18	111	Q8N4B5
TLGSTTVAAGGTSTG	NUP58	11	Q9BVL2
GGTTATTTTASTGLS	NUP58	156	Q9BVL2
GGATSGSSQTSISGD	MAP3K1	616	Q13233
TGASGATVVSGSASG	TAF5	166	Q15542
SGSQVVASSTSTGAG	RFX1	361	P22670
DGNGTTSGVGTGSSV	SCN3A	1066	Q9NY46
ASSVGSQSSAGSVGS	AFF1	1111	P51825
TSSSGVDISSGSGGS	RP1L1	1196	Q8IWN7
SGTASTVGGTTGSTA	UBQLN1	336	Q9UMX0
TVGGTTGSTASGTSG	UBQLN1	341	Q9UMX0
GGGATGATTAAVSTS	TMEM131	6	Q92545
SVSGSGSTAGSRTGS	PLEC	4616	Q15149
HGVSSGSSSSGGTPV	UBN1	911	Q9NPG3
ESSAGAGTGTGTSTP	ZNF362	131	Q5T0B9
GSVSSSTGAISTTTG	UBR4	2931	Q5T4S7
TGGTVESDGSTESTG	TNRC6A	666	Q8NDV7
SSSSTGSEVGGQSTG	TNRC6B	561	Q9UPQ9
THGTTSICSVTSGAG	KLHL29	26	Q96CT2