Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RASA3 FKBP1B ITPR3

7.59e-0518933GO:0015278
GeneOntologyMolecularFunctionhistone H3K27me2/H3K27me3 demethylase activity

KDM6A UTY

2.13e-045932GO:0071558
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RASA3 FKBP1B ITPR3

4.00e-0431933GO:0099604
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KA1 RPS6KA6

4.44e-047932GO:0004711
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RASA3 FKBP1B ITPR3

4.82e-0433933GO:0005217
GeneOntologyMolecularFunctionATP-dependent activity

DDX12P MDN1 MYO1A ATP8A2 HSPH1 KIF4A ATP13A5 MYH15 ABCG5 AQR

5.73e-046149310GO:0140657
GeneOntologyMolecularFunctionhistone modifying activity

SETD2 BRCA2 KAT2A KDM6A UTY PRDM2

7.08e-04229936GO:0140993
DomainTPR_8

TTC39B CFAP70 KDM6A UTY

1.46e-0453944PF13181
DomainTox-GHH_dom

TENM4 TENM1

1.49e-044942IPR028916
DomainTox-GHH

TENM4 TENM1

1.49e-044942PF15636
DomainTen_N

TENM4 TENM1

1.49e-044942IPR009471
DomainTen_N

TENM4 TENM1

1.49e-044942PF06484
DomainTENEURIN_N

TENM4 TENM1

1.49e-044942PS51361
DomainC2_dom

OTOF RASA3 PIK3CB TNS2 PLCG2 RASAL2

1.80e-04164946IPR000008
DomainYD

TENM4 TENM1

2.48e-045942IPR006530
DomainRibosomal_S6_kinase_II

RPS6KA1 RPS6KA6

3.71e-046942IPR016239
Domain-

MDN1 HMCN1 COL14A1 COL6A5

5.29e-04749443.40.50.410
DomainVWFA

MDN1 HMCN1 COL14A1 COL6A5

7.80e-0482944PS50234
DomainVWA

MDN1 HMCN1 COL14A1 COL6A5

8.54e-0484944SM00327
Domain-

OTOF RASA3 PIK3CB PLCG2 RASAL2

9.10e-041489452.60.40.150
DomainTPR_REGION

TTC39B CFAP70 KDM6A UTY RGPD5

1.48e-03165945PS50293
DomainTPR

TTC39B CFAP70 KDM6A UTY RGPD5

1.48e-03165945PS50005
DomainVWF_A

MDN1 HMCN1 COL14A1 COL6A5

1.57e-0399944IPR002035
DomainNHL

TENM4 TENM1

1.89e-0313942PS51125
DomainRasGAP

RASA3 RASAL2

2.19e-0314942SM00323
DomainRasGAP_CS

RASA3 RASAL2

2.19e-0314942IPR023152
DomainRasGAP

RASA3 RASAL2

2.52e-0315942PF00616
DomainRAS_GTPASE_ACTIV_1

RASA3 RASAL2

2.52e-0315942PS00509
DomainRAS_GTPASE_ACTIV_2

RASA3 RASAL2

2.52e-0315942PS50018
Domain-

RASA3 RASAL2

2.87e-03169421.10.506.10
DomainCarboxyPept-like_regulatory

TENM4 CILP

3.24e-0317942IPR008969
DomainPI3_PI4_kinase

PI4K2B PIK3CB

3.64e-0318942PF00454
DomainPI3_4_KINASE_1

PI4K2B PIK3CB

3.64e-0318942PS00915
DomainPI3_4_KINASE_2

PI4K2B PIK3CB

3.64e-0318942PS00916
DomainPI3/4_kinase_cat_dom

PI4K2B PIK3CB

3.64e-0318942IPR000403
DomainRasGAP_dom

RASA3 RASAL2

3.64e-0318942IPR001936
DomainPI3_4_KINASE_3

PI4K2B PIK3CB

3.64e-0318942PS50290
DomainTPR

TTC39B CFAP70 KDM6A UTY

4.10e-03129944SM00028
Domain-

ATP8A2 ATP13A5 PMM2

4.12e-03649433.40.50.1000
DomainC2

OTOF RASA3 PLCG2 RASAL2

4.33e-03131944PF00168
DomainTPR_repeat

TTC39B CFAP70 KDM6A UTY

4.57e-03133944IPR019734
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SRRT SETD2 POLR3D MDN1 FAM50A KIF4A DIDO1 KAT2A API5 KDM6A AQR NUP153 ESF1

3.90e-061014951332416067
Pubmed

An H-YDb epitope is encoded by a novel mouse Y chromosome gene.

KDM6A UTY

7.38e-0629528944031
Pubmed

Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.

KDM6A UTY

7.38e-06295218434530
Pubmed

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.

KDM6A UTY

7.38e-06295227533081
Pubmed

Positive and negative selection on mammalian Y chromosomes.

KDM6A UTY

7.38e-06295215758204
Pubmed

Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.

KDM6A UTY

7.38e-06295231097364
Pubmed

Oxidative Stress Orchestrates MAPK and Nitric-Oxide Synthase Signal.

RPS6KA1 NOS1

7.38e-06295233228180
Pubmed

A novel role of the chromokinesin Kif4A in DNA damage response.

BRCA2 KIF4A

7.38e-06295218604178
Pubmed

New nomenclature for chromatin-modifying enzymes.

SETD2 KAT2A KDM6A PRDM2

1.85e-055795418022353
Pubmed

The UTX gene escapes X inactivation in mice and humans.

KDM6A UTY

2.21e-0539529499428
Pubmed

Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages.

PLCG2 ITPR3

2.21e-0539529013981
Pubmed

Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample.

ZNF804A NOS1

2.21e-05395219844207
Pubmed

The E3 Ligases Spsb1 and Spsb4 Regulate RevErbα Degradation and Circadian Period.

SPSB1 SPSB4

2.21e-05395231607207
Pubmed

Discovery and refinement of loci associated with lipid levels.

TTC39B SETD2 PMVK BRCA2 APOB ABCG5

2.58e-0521195624097068
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HMCN1 COL14A1 COL6A5 APOB

2.93e-056495422261194
Pubmed

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

TTC39B BPI DIPK1A ATP8A2

2.93e-056495420889312
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

SRRT SETD2 MDN1 BRCA2 KAT2A API5 CAVIN2 FAM83H

3.52e-0545395829656893
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MDN1 MYO1A RPN1 FAM50A HSPH1 TENM1 MYH15 APOB KAT2A HSD17B4 PRX CAVIN2 ESF1 RGPD5

3.68e-051442951435575683
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MTMR6 POLR3D AMMECR1L B3GNT5 DIPK1A HSPH1 CRYBG1 DIDO1 APOB NUP153 PRDM2 ESF1

4.01e-051084951211544199
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM1

4.41e-05495210225957
Pubmed

Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms.

KDM6A UTY

4.41e-0549529854018
Pubmed

ESCRT machinery potentiates HIV-1 utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) signaling cascade.

PLCG2 ITPR3

4.41e-05495221875593
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

RASA3 ITPR3

4.41e-05495210828023
Pubmed

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.

SETD2 KDM6A

4.41e-05495220054297
Pubmed

Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC.

SETD2 KDM6A

4.41e-05495223644518
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM6A UTY

4.41e-05495232732223
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM1

4.41e-05495212000766
Pubmed

Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.

KDM6A UTY

4.41e-05495210767340
Pubmed

Understanding the development of oral epithelial organs through single cell transcriptomic analysis.

KCNH7 COL14A1 PRSS23 SLC4A4

4.92e-057395435831953
Pubmed

A protein interaction landscape of breast cancer.

PHF1 DOCK4 RIN1 MDN1 BRCA2 HSPH1 CAVIN2 NUP153 ITPR3

6.13e-0563495934591612
Pubmed

RSK2 is a modulator of craniofacial development.

RPS6KA1 RPS6KA6

7.34e-05595224416220
Pubmed

Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells.

SPSB1 SPSB4

7.34e-05595216672355
Pubmed

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.

RPS6KA1 RPS6KA6

7.34e-05595237068088
Pubmed

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

SPSB1 SPSB4

7.34e-05595216369487
Pubmed

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.

ZNF804A TBC1D9

7.34e-05595212970790
Pubmed

Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.

RPS6KA1 RPS6KA6

7.34e-05595211160957
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SRRT RIN1 MDN1 RASA3 RPN1 HSPH1 KIF4A PLCG2 AQR RASAL2 ESF1 FAM83H PMM2

7.95e-051353951329467282
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

NDNF TTC39B ATP13A5 PRSS23 ZNF804A NOS1 TBC1D9

7.98e-0537695724154525
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

SRRT SNX14 KCNH7 FKBP1B

8.93e-058595423055939
Pubmed

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

RPS6KA1 RPS6KA6

1.10e-04695212832467
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

PLCG2 ITPR3

1.10e-04695221762810
Pubmed

The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.

SPSB1 SPSB4

1.10e-04695220603330
Pubmed

Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.

SPSB1 SPSB4

1.10e-04695220561531
Pubmed

The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway.

SPSB1 SPSB4

1.10e-04695215713673
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD2 MTMR6 RPN1 KIF4A DIDO1 KDM6A ESF1 RGPD5

1.34e-0454995838280479
Pubmed

UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.

KDM6A UTY

1.54e-04795229551674
Pubmed

Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.

SPSB1 SPSB4

1.54e-04795221199876
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM1

1.54e-04795212915301
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SRRT RPN1 HSPH1 CRYBG1 DIDO1 PRSS23 AQR NUP153 RASAL2 ESF1 FAM83H ITPR3

1.62e-041257951236526897
Pubmed

Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.

TENM4 RPN1 NUP153

1.68e-043995324095980
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

RPS6KA1 HSPH1 RNF113A SCYL1 TNS2 MYH15 SLC4A4 PRX ESF1 FAM83H

1.95e-04910951036736316
Pubmed

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.

SPSB1 SPSB4

2.05e-04895228931592
Pubmed

Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.

BRCA2 HSD17B4

2.05e-04895218086758
Pubmed

Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase.

OTOF HSPH1

2.05e-04895214563843
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM1

2.05e-04895210331952
Pubmed

UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.

KDM6A UTY

2.05e-04895236412518
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SRRT SETD2 MDN1 TIGD2 RPN1 KIF4A DIDO1 KAT2A KDM6A NUP153 PRDM2 ITPR3

2.12e-041294951230804502
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

TTC39B SETD2 H1-8 BRCA2 SCYL1 KIF4A DIDO1 APOB PLCG2

2.25e-0475495935906200
Pubmed

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.

KDM6A UTY

2.62e-04995223028370
Pubmed

Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.

APOB ABCG5

2.62e-04995220370913
Pubmed

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.

KDM6A UTY

2.62e-04995222949634
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SRRT SETD2 MDN1 DIDO1 KDM6A NUP153 TBC1D9 PRDM2 ESF1

2.73e-0477495915302935
Pubmed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

KIF4A KDM6A

3.28e-041095229101321
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM1

3.28e-041095238713721
Pubmed

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.

NDNF OTOF NOS1

3.53e-045095336774552
Pubmed

90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling.

RPS6KA1 TNS2

4.00e-041195215117958
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SRRT RPS6KA1 DIDO1 HSD17B4 ZZEF1 AQR RASAL2 ESF1

4.16e-0465095838777146
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SRRT MDN1 RPN1 HSPH1 APOB API5 HSD17B4 AQR NUP153 RASAL2 PRDM2 ESF1

5.06e-041425951230948266
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM6A UTY

5.65e-041395214660691
Pubmed

UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program.

KDM6A UTY

5.65e-041395222192413
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

SETD2 MDN1 PIK3CB SCYL1 ZZEF1

5.98e-0424795532989298
Pubmed

Phenotypic annotation of the mouse X chromosome.

RPS6KA6 KIF4A KDM6A

6.33e-046195320548051
Pubmed

Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.

PIK3CB PLCG2

6.58e-041495220041213
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

CILP COL14A1 CPA3 APOB

7.06e-0414695427068509
Pubmed

Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.

CYP2B6 CYP2U1

7.57e-041595229968852
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

RPN1 TENM1 CRYBG1 UNC80 TBC1D9 PRDM2 PMM2

8.10e-0455295710737800
Pubmed

KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.

KDM6A UTY

8.64e-041695235212626
Pubmed

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

SFTPD SPSB1

9.78e-041795223408915
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

SETD2 BRCA2 KDM6A

9.86e-047195328319113
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

DOCK4 TENM4 UNC80

9.86e-047195333541421
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

MTMR6 SCYL1 APOB API5 UNC80 PMM2

1.05e-0342095628065597
Pubmed

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

SPSB1 SPSB4

1.10e-031895215601820
Pubmed

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics.

NDNF NOS1

1.10e-031895226727548
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

KDM6A UTY

1.10e-031895212023983
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HMCN1 SFTPD COL14A1 COL6A5

1.16e-0316795422159717
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SRRT SETD2 BRCA2 RPN1 KIF4A DIDO1 API5 NUP153 ESF1

1.21e-0395495936373674
Pubmed

The DNA sequence and analysis of human chromosome 13.

MTMR6 BRCA2 ATP8A2 HSPH1

1.24e-0317095415057823
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SRRT SETD2 AQR NUP153 ESF1 ITPR3

1.33e-0344095634244565
Pubmed

The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.

NOS1 KDM6A

1.36e-032095235177643
Pubmed

Enhancer viruses for combinatorial cell-subclass-specific labeling.

NDNF NOS1

1.36e-032095233789083
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

KDM6A UTY

1.36e-032095219047629
Pubmed

Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.

BRCA2 PLCG2

1.65e-032295218095154
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

TENM1 CSMD3

1.65e-032295235245678
Pubmed

Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.

SFTPD KDM6A

1.65e-032295225079229
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MDN1 RPN1 HSPH1 API5 HSD17B4 NUP153 FAM83H

1.86e-0363895733239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MDN1 KDM6A UTY CAVIN2 RASAL2 ESF1 ITPR3

1.86e-0363895731182584
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

CYP2B6 PIK3CB APOB ABCG5

1.94e-0319295420602615
Pubmed

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

RIN1 TNS2 PLCG2

1.95e-039095316273093
Pubmed

Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.

MTMR6 UTY

1.96e-032495217452356
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

PLCG2 ITPR3

1.96e-032495210843712
CytobandEnsembl 112 genes in cytogenetic band chr2p23

CLIP4 OTOF TRMT61B FKBP1B

2.70e-04149954chr2p23
Cytoband2p23.2

CLIP4 TRMT61B

3.26e-04139522p23.2
Cytoband13q12.3

BRCA2 HSPH1

9.53e-042295213q12.3
Cytoband13q12

MTMR6 ATP8A2

1.14e-032495213q12
Cytoband3q28

B3GNT5 OSTN

1.77e-03309523q28
CytobandEnsembl 112 genes in cytogenetic band chr3q22

H1-8 PIK3CB COL6A5

2.83e-03135953chr3q22
Cytoband11q14.1

TENM4 PRSS23

3.46e-034295211q14.1
Cytoband3q22.1

H1-8 COL6A5

3.46e-03429523q22.1
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC39B CFAP70 KDM6A UTY RGPD5

1.02e-04115735769
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA3 RASAL2

7.09e-0410732830
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA1 RPS6KA6

8.64e-04117321156
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 HMCN1 TENM1 MYH15 APOB SLC4A4 CSMD3 UNC80

6.03e-091849582cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 HMCN1 TENM1 MYH15 APOB SLC4A4 CSMD3 UNC80

6.03e-09184958ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 HMCN1 TENM1 MYH15 APOB SLC4A4 CSMD3 UNC80

6.03e-091849582b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SETD2 HSPH1 CRYBG1 PLCG2 KDM6A PRDM2 RGPD5

1.79e-071919571ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CNTN3 ATP13A5 MYH15 COL6A5 UNC80

1.23e-06160956c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CNTN3 ATP13A5 MYH15 COL6A5 UNC80

1.23e-0616095625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK4 OSTN SPSB4 PRSS23 SLC4A4 ZNF804A

1.47e-06165956d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ATP13A5 MYH15 CSMD3 NOS1 UNC80

2.07e-06175956887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 SPSB1 COL14A1 SPSB4 PRSS23 SLC4A4

2.44e-06180956c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCellAT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NDNF CYP2B6 SFTPD ATP8A2 CAVIN2 ITPR3

2.86e-061859563b3268e3f99121124e33086cac88479808d31630
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLIP4 MTMR6 OSTN TENM1 SLC4A4 ZNF804A

3.33e-0619095639ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN1 CNTN3 COL14A1 MYH15 NOS1 UNC80

3.87e-06195956d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN1 CNTN3 COL14A1 MYH15 NOS1 UNC80

3.87e-0619595619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OTOF SLC5A12 FKBP1B ABCG5 CAVIN2

1.44e-051449559b59a5723cb1855e0c4a83b7714535cc4de9c8e5
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Platelets|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OTOF SLC5A12 FKBP1B ABCG5 CAVIN2

1.44e-05144955e2d7547bf5152e14003aaf2713f695a153d195a1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 CNTN3 ATP13A5 CSMD3 UNC80

1.49e-0514595596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TENM1 CNTN3 ATP13A5 CSMD3 UNC80

2.54e-05162955bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK4 OSTN SPSB4 PRSS23 SLC4A4

2.85e-0516695559d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-8 BPI HMCN1 SPSB4 VWDE

2.94e-0516795578909f685ccd1321064eb0887caf9263e0e54879
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RIN1 PIK3CB PRX CAVIN2 RASAL2

3.38e-05172955490745024730df6357f6c2b81d7a64e21557c0d5
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 CILP COL6A5 CPA3 CSMD3

3.67e-0517595559249c9e83952d7277010e7be3c779e26399eb5d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 CILP COL6A5 CPA3 CSMD3

3.67e-05175955b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTPD COL14A1 COL6A5 UTY CAVIN2

3.87e-05177955b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PI4K2B CYP2B6 CYP2U1 CFAP70 PLEKHM1

4.20e-0518095512f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PI4K2B CYP2B6 CYP2U1 CFAP70 PLEKHM1

4.20e-051809551bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PI4K2B CYP2B6 CYP2U1 CFAP70 PLEKHM1

4.20e-051809552a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HMCN1 PRSS23 CAVIN2 RASAL2

4.54e-05183955dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HMCN1 PRSS23 CAVIN2 RASAL2

4.54e-051839554759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTMR6 OSTN TENM1 SLC4A4 ZNF804A

5.16e-051889558de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR6 RASA3 RPN1 ATP8A2 RPS6KA1

5.29e-051899556dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK4 HMCN1 CNTN3 COL14A1 CSMD3

5.29e-05189955203c80030df08ae112f9ae4043709f455d87ce89
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR6 RASA3 RPN1 ATP8A2 RPS6KA1

5.29e-051899553ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR6 RASA3 RPN1 ATP8A2 RPS6KA1

5.29e-05189955875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR6 RASA3 RPN1 ATP8A2 RPS6KA1

5.29e-0518995597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

DOCK4 HMCN1 ATP8A2 COL14A1 CAVIN2

5.43e-0519095571e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 CILP SPSB1 COL14A1 SLC4A4

5.84e-0519395564edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYP2B6 ATP13A5 PRSS23 SLC4A4 CAVIN2

5.99e-051949552172d951896265243d14996eacce5aab5e14e26e
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 HMCN1 ATP8A2 COL6A5 CAVIN2

5.99e-05194955d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 HMCN1 ATP8A2 COL6A5 CAVIN2

5.99e-05194955e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCellmild_COVID-19_(asymptomatic)|World / disease group, cell group and cell class (v2)

MTMR6 OTOF PLCG2 KDM6A CAVIN2

6.29e-051969558cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

NDNF SFTPD COL14A1 COL6A5 UTY

6.44e-051979550a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SCGB1D1 TIGD2 ATP8A2 SPSB4 UNC80

6.44e-05197955ff4df77117165b6b25315e29b0722cc136eba607
ToppCell(7)_Epithelial_cells-(7)_Epithelial-E_(AT2)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

NDNF CYP2B6 HSPH1 PLCG2 UTY

6.60e-05198955498f11441c0a0982738537bcfcfc2877866b7400
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2B6 TENM4 SPSB1 PRSS23 SLC4A4

6.60e-0519895519d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH7 ATP8A2 CSMD3 UNC80 RASAL2

6.60e-051989550ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-05200955f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-05200955cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-05200955c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-052009554fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-05200955310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

TENM1 CNTN3 CSMD3 ZNF804A UNC80

6.92e-05200955961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BPI TNS2 NPIPB2 RASAL2

1.68e-041299542f30b4897343586c9b49a1d2bec3007ec737085c
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like|E16.5-samps / Age Group, Lineage, Cell class and subclass

PHF1 RIN1 PCDHB12 KAT2A

1.83e-041329549633653dba1edee47d915212fb6e68426da49de5
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

KCNH7 ATP8A2 CSMD3 NOS1

2.23e-0413995413247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPSB4 PRSS23 SLC4A4 ZNF804A

2.56e-041449540bbe670454846cf9bc7464ae4e91488415c4111d
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

CLIP4 PI4K2B NDNF SFTPD

2.69e-041469544511916904c1fac252cb68e871b782207f8137b3
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

HMCN1 CILP COL14A1 CPA3

2.91e-041499543904f8ce9078de238600ceceee0116af52256a1c
ToppCellTCGA-Lung|World / Sample_Type by Project: Shred V9

NDNF B3GNT5 SFTPD COL6A5

2.99e-041509548c133206786e8f22bb70f2a7de9c0cb7f9ea9313
ToppCellEpithelial-Epithelial-B_(AT1-AT2-progenitors)|Epithelial / shred on cell class and cell subclass (v4)

PI4K2B MDN1 PMVK SFTPD

3.30e-04154954770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CILP SPSB1 RNF113A COL14A1

3.46e-04156954d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMMECR1L RPS6KA6 KAT2A HSD17B4

3.46e-0415695414e2f693a75f1075f40cc7b16ee430262a5de016
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CILP SPSB1 RNF113A COL14A1

3.46e-04156954363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 HMCN1 MYH15 TBC1D9

3.64e-041589547960337d87afecf2692ab65e5991f052ceddfacc
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OSTN RPS6KA6 CNTN3 PRSS23

3.72e-041599541baf0eaf9684668146a63192e77eec6c3c7a37f8
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLIP4 SFTPD PLCG2 FAM83H

3.72e-04159954a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 CILP PLCG2 TBC1D9

3.81e-0416095486fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

FAM50A TENM1 COL14A1 KAT2A

3.90e-04161954048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell367C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 CYP2U1 FKBP1B ITPR3

3.90e-041619548de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLIP4 PI4K2B NDNF SFTPD

4.00e-0416295406f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLIP4 PI4K2B NDNF SFTPD

4.00e-04162954d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

OSTN SPSB4 PRSS23 ZNF804A

4.09e-04163954db6b7ce6f7221bb73c5e650ac51cdd5d7ef00675
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

DOCK4 RPS6KA6 UNC80 RASAL2

4.09e-041639546ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

DOCK4 RPS6KA6 UNC80 RASAL2

4.09e-0416395426661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH7 ATP8A2 VWDE UNC80

4.19e-04164954be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

ATP8A2 CPA3 PRX CAVIN2

4.28e-041659545fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

ATP8A2 CPA3 PRX CAVIN2

4.28e-0416595493d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TENM4 CNTN3 COL14A1 UNC80

4.38e-0416695465dafed953b01a9830b54309af75c7a561e88336
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLIP4 COL14A1 APOB CFAP70

4.38e-04166954b64ab3d13b76bba3c305ebbfc96f983cd6ca30c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF RPN1 RNF113A FKBP1B

4.38e-04166954dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 CILP CPA3 CSMD3

4.48e-04167954e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH7 ATP8A2 VWDE UNC80

4.48e-04167954c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CLIP4 B3GNT5 ZNF804A FAM83H

4.48e-041679549efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

CLIP4 B3GNT5 ZNF804A FAM83H

4.48e-04167954904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellTuft-tuft-1|World / Class top

KCNH7 SPSB4 PLCG2 ELAC1

4.58e-041689548ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 CILP OSTN UNC80

4.58e-04168954e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TENM4 MYO1A CYP2U1 RGPD5

4.58e-04168954d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF113A CYP2U1 SPSB4 FKBP1B

4.58e-04168954d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 CILP OSTN UNC80

4.58e-04168954b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 TNS2 PRSS23 CAVIN2

4.69e-0416995458136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-8 HMCN1 PRSS23 CAVIN2

4.69e-041699548dba7546adc6b1345933eec81fc77fc9611fae60
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 BRCA2 KIF4A SPSB4

4.69e-04169954e7514956b2e4298222ec443f98b2f5289451786e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 TNS2 PRSS23 CAVIN2

4.69e-0416995404c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TENM4 MYO1A CYP2U1 RGPD5

4.69e-04169954ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCellfacs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-8 HMCN1 PRSS23 CAVIN2

4.69e-04169954d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH7 ATP8A2 VWDE UNC80

4.69e-04169954b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A5 MYH15 CSMD3 UNC80

4.69e-0416995412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 RIN1 MYO1A PRSS23

4.79e-041709548e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 RIN1 MYO1A PRSS23

4.79e-0417095467d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellileum|World / shred on tissue and cell subclass

MYO1A APOB SLC5A12 ABCG5

4.79e-041709549f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2B6 COL6A5 PRSS23 SLC4A4

4.90e-0417195425c1979e972c959e1ce4c57804f976f53a247ad7
DiseaseKabuki syndrome (implicated_via_orthology)

KDM6A UTY

2.88e-053922DOID:0060473 (implicated_via_orthology)
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA1 RPS6KA6

5.75e-054922DOID:3783 (implicated_via_orthology)
DiseasePartial Fetal Alcohol Syndrome

RPS6KA1 NOS1

9.56e-055922C3661483
DiseaseAlcohol Related Neurodevelopmental Disorder

RPS6KA1 NOS1

9.56e-055922C0814154
DiseaseAlcohol Related Birth Defect

RPS6KA1 NOS1

1.43e-046922C3146244
Diseasecholesteryl ester 24:4 measurement

TTC39B TNS2

2.00e-047922EFO_0021447
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

BRCA2 COL14A1 KDM6A

3.79e-0445923DOID:3748 (is_implicated_in)
Diseasepost-traumatic stress disorder

DOCK4 SLC4A4 ZNF804A NOS1 VWDE

4.34e-04202925EFO_0001358
Diseasefree cholesterol to total lipids in small HDL percentage

TTC39B APOB ABCG5

5.48e-0451923EFO_0022285
Diseasecardiomyopathy (biomarker_via_orthology)

FKBP1B NOS1

7.33e-0413922DOID:0050700 (biomarker_via_orthology)
DiseaseFetal Alcohol Spectrum Disorders

RPS6KA1 NOS1

7.33e-0413922C2985290
DiseaseSpastic Paraplegia, Hereditary

UBAP1 CYP2U1

8.54e-0414922C0037773
Diseasemalignant pleural mesothelioma (is_marker_for)

SETD2 KDM6A

8.54e-0414922DOID:7474 (is_marker_for)
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

RPS6KA1 ZZEF1

8.54e-0414922EFO_0006830, EFO_0006896
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

SETD2 CSMD3 ZNF804A KDM6A

1.21e-03148924C0279702
DiseaseFetal Alcohol Syndrome

RPS6KA1 NOS1

1.27e-0317922C0015923
Diseaseschizophrenia (implicated_via_orthology)

CSMD3 ZNF804A NOS1

1.27e-0368923DOID:5419 (implicated_via_orthology)
DiseaseHypercholesterolemia, Familial

APOB ABCG5

1.42e-0318922C0020445
Diseasephosphatidylethanolamine measurement

CNTN3 APOB PLCG2 ZZEF1

2.14e-03173924EFO_0010228
Diseasemental or behavioural disorder

TTC39B BPI DIPK1A ATP8A2

2.42e-03179924EFO_0000677
DiseaseCoronary heart disease

APOB ABCG5

2.54e-0324922C0010068
DiseaseDyslipidemias

APOB ABCG5

2.54e-0324922C0242339
DiseaseDyslipoproteinemias

APOB ABCG5

2.54e-0324922C0598784
Diseasenephrotic syndrome (biomarker_via_orthology)

APOB NOS1

2.54e-0324922DOID:1184 (biomarker_via_orthology)
DiseaseIntellectual Disability

SNX14 SETD2 ATP8A2 RNF113A KIF4A PMM2

2.78e-03447926C3714756
DiseaseHMG CoA reductase inhibitor use measurement

SETD2 BRCA2 APOB ITPR3

2.94e-03189924EFO_0009932

Protein segments in the cluster

PeptideGeneStartEntry
ITVAFIFSKGKPFRK

ATP13A5

1056

Q4VNC0
KKTEAFIPFSLGKRI

CYP2B6

421

P20813
GGFKAPITSEFRKTI

AMMECR1L

256

Q6DCA0
AIDFKSRGFKLFPGK

CSMD3

451

Q7Z407
PFRITFPVRSGKGKK

AQR

746

O60306
KGGTKEKRLAAQFIP

API5

36

Q9BZZ5
GIFAPLSKISKAKGR

CLIP4

341

Q8N3C7
LVKGAKKLGFVFTAR

ATP8A2

531

Q9NTI2
TLAGPFRSEAKKTKV

RASA3

171

Q14644
KRIFSSEKSKPFVFG

RGPD5

1546

Q99666
GFSKDIKVPKSRYLG

KAT2A

626

Q92830
KQVFGILKAPFREKG

ITPR3

516

Q14573
GFAGIKKLQKFLGRP

MDN1

2791

Q9NU22
SKARGATGSFKLVPK

H1-8

116

Q8IZA3
KPIIVGSSKFRSKGR

MTMR6

171

Q9Y217
LAFGKTKIFIRSPKT

MYO1A

671

Q9UBC5
KTVNRKFFGFKFPGL

KCNH7

151

Q9NS40
NKGKLKVLGTAFDPF

HSPH1

216

Q92598
KGPFKTIKFGTNIDL

KDM6A

1076

O15550
SFKPKGGVIFSVKIY

ESF1

371

Q9H501
PFKVPGFFSKRLKGS

RASAL2

36

Q9UJF2
SIFIGGSFILKKKGL

NIPA2

21

Q8N8Q9
KRKGAKFLRFAPVSS

NDNF

356

Q8TB73
QGSFGKVFLVRKKTG

RPS6KA6

81

Q9UK32
KVFLVRKKTGPDAGQ

RPS6KA6

86

Q9UK32
KAVKSGFRSVPLKNG

PLCG2

1156

P16885
TFLFKKPGRKGAAGR

RNF113A

16

O15541
TGGSRSNKFKFLKPI

PCDHB12

756

Q9Y5F1
AGFSRKPTLDFKKTV

HMCN1

321

Q96RW7
GTPTKRRAIGFKKLA

NOS1

726

P29475
IETKKKRSFSGFGSP

OSTN

76

P61366
SGSYFVKDPKRKIIG

PI4K2B

131

Q8TCG2
ATDPKVKTISKGFFG

B3GNT5

336

Q9BYG0
KKETFIPFGIGKRVC

CYP2U1

476

Q7Z449
TPKINSRFFGEGTKK

APOB

291

P04114
DKGKFGFLLPESRIK

CPA3

381

P15088
EKGEKKLFGFSFVPL

DOCK4

496

Q8N1I0
GFVVSVVKKTGLAPF

BRCA2

3076

P51587
PFKFRIGKQEVIKGF

FKBP1B

46

P68106
LKGFKGDTPVTFIRA

CFAP70

21

Q5T0N1
KAPRGKFGGYKLLVT

COL14A1

51

Q05707
GKLDPQKAFFSGRLK

HSD17B4

701

P51659
DFIVTKARGKSGPLF

FAM50A

266

Q14320
IPKESKFRLTTKFFG

BPI

316

P17213
SKSGGFPRIDFALKK

COL6A5

1076

A8TX70
KKSPFGKDVRLVSLG

DDX12P

266

Q92771
KKFPGSAALVGAVRK

DIDO1

626

Q9BTC0
FKTKDSPGVFSKLGV

ABCG5

356

Q9H222
KKGGFVPYRDSKLTR

KIF4A

281

O95239
EKVFDPKVFTFGLGK

CRYBG1

741

Q9Y4K1
PKVFTFGLGKKKESQ

CRYBG1

746

Q9Y4K1
DSKVGKFVPKILGTF

FAM83H

1161

Q6ZRV2
KVSPLTFGRKKVREG

CAVIN2

291

O95810
LFDKPTRGTTVQKFK

DIPK1A

136

Q5T7M9
GLPFSSKIKLRKFSG

CNTN3

266

Q9P232
ATKPILKGKKFGPFV

PRDM2

46

Q13029
VKTLFLKLPGKRGFG

OTOF

886

Q9HC10
FAIATKRGGALKKGP

PHF1

141

O43189
KLPKKRGTFIEFRNG

PMM2

111

O15305
GGPSFFKIITAKAVL

PLEKHM1

741

Q9Y4G2
RRKGPFKTIKFGTNI

UTY

1021

O14607
GGVKKKTFTPNIISR

POLR3D

51

P05423
GDLGPTKREKFKRSF

RIN1

231

Q13671
AGAVVLTPLFKVGKF

SCYL1

326

Q96KG9
SAIPFGEKKRKKGAS

MYH15

641

Q9Y2K3
GTQKLRVGFLKPKFK

PRSS23

186

O95084
RETKIKGKSGRFFTV

RPN1

101

P04843
KGKSGRFFTVKLPVA

RPN1

106

P04843
AAVPSVFGKGIKFAI

TENM1

2516

Q9UKZ4
VSSRGGKKFLPVLKE

PIK3CB

526

P42338
VLLFSGKRKSGKDFV

PMVK

11

Q15126
ITGFLLAGKPVFKFQ

SCGB1D1

31

O95968
PLSGKKFKGPEFVRK

SRRT

716

Q9BXP5
TTKVLPFNKKGSAVF

CILP

551

O75339
CVVGKAKKPRAFKGT

TIGD2

226

Q4W5G0
RVFGKGFKELPSIKC

VWDE

946

Q8N2E2
DKFKTPAKVGLPIGF

UBAP1

26

Q9NZ09
AGKSIPTEKFAVRKA

TTC39B

506

Q5VTQ0
KVKFTSAVKLSEGGP

UNC80

1121

Q8N2C7
KIVGKFPGQILRSSF

TRMT61B

191

Q9BVS5
GEKIFKTAGFVKPFT

SFTPD

261

P35247
FGISRIGSKIKGVFK

SNX14

501

Q9Y5W7
FRGLKGKKLYPVVSA

SPSB4

201

Q96A44
FRGLKGKKLYPVVSA

SPSB1

201

Q96BD6
FSLPKFGLSGPKVAK

PRX

931

Q9BXM0
GFVTVSLKPDKGKRA

TBC1D9

981

Q6ZT07
FGKGVKFALKDGRVT

TENM4

2566

Q6N022
SFGFSVVEKKRPGKL

ELAC1

186

Q9H777
KFSKPIGDFKFGVSS

NUP153

951

P49790
TKKRVSSFPGNKIGL

NPIPB2

106

A6NJ64
IKGPMFKGVASSRFL

SETD2

41

Q9BYW2
FKGVASSRFLPKGTK

SETD2

46

Q9BYW2
KKVTFKAGPRLQFLF

ZZEF1

1161

O43149
TRFLFILLGPKGKAK

SLC4A4

321

Q9Y6R1
GNTTKSGKSLFRFPK

THAP10

11

Q9P2Z0
SSGIGVFFAIKERKK

SLC5A12

21

Q1EHB4
TTSKIFGFVAKKPGS

TNS2

1361

Q63HR2
KIGFSFAFPKKASVK

ZNF804A

211

Q7Z570
GSFGKVFLVRKVTRP

RPS6KA1

71

Q15418